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MAGQSDRKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTASANLQALKSGGLVEA RREGTRQYYRIAGEDVARLFALVQVVADEHLADVAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRP HEEYQAGHIPGAINIPIAELADRLAELTGDRDIVAYCRGAYCVMAPDAVRIARDAGREVKRLDDGMLEWR LAGLPVDEGAPVGHGD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0324 | - | - | 100% (226) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) |
M. tuberculosis H37Rv | Rv1674c | - | 3e-45 | 45.33% (214) | transcriptional regulatory protein |
M. tuberculosis H37Rv | Rv3116 | moeB2 | 6e-10 | 34.21% (114) | molybdenum cofactor biosynthesis protein MoeB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0332 | - | 1e-124 | 99.56% (226) | ArsR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_1138 | - | 5e-08 | 40.00% (85) | rhodanese domain-containing protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2562c | - | 4e-08 | 31.00% (100) | transcriptional regulatory protein ArsR |
M. marinum M | MMAR_2139 | - | 7e-07 | 35.53% (76) | transcriptional regulatory protein |
M. avium 104 | MAV_5108 | - | 2e-07 | 32.41% (108) | transcriptional regulator, ArsR family protein |
M. smegmatis MC2 155 | MSMEG_6425 | - | 5e-08 | 32.50% (120) | rhodanese-like domain-containing protein |
M. thermoresistible (build 8) | TH_1234 | - | 2e-08 | 48.21% (56) | metallo-beta-lactamase family protein |
M. ulcerans Agy99 | MUL_2527 | moeB1 | 1e-05 | 33.33% (111) | molybdopterin biosynthesis-like protein MoeZ |
M. vanbaalenii PYR-1 | Mvan_4028 | - | 2e-07 | 37.50% (88) | rhodanese domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv0324|M.tuberculosis_H37Rv -------------------------------------------------- Mb0332|M.bovis_AF2122/97 -------------------------------------------------- Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu MKFIQYYLDCLSHASYLIADDKTGRAVVVDPQRDVAEYLSDAEKYGYTIE MUL_2527|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv -------------------------------------------------- Mb0332|M.bovis_AF2122/97 -------------------------------------------------- Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu LVIETHFHADFLSGHLELAEATGAKIVYSSVAETEFESMGVADGERYSLG MUL_2527|M.ulcerans_Agy99 -----------MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQK MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv -------------------------------------------------- Mb0332|M.bovis_AF2122/97 -------------------------------------------------- Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu DVTLEFLHTPGHTPESLSIVVYEHADDEIPYGVLTGDTLFIGDVGRPDLL MUL_2527|M.ulcerans_Agy99 RLKNARVLVIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIH MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv -------------------------------------------------- Mb0332|M.bovis_AF2122/97 -------------------------------------------------- Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu ASIGYTREELADKLYDSLHHKLMTLPDATRVYPAHGAGSACGKNLSTELW MUL_2527|M.ulcerans_Agy99 GVADVGRSK--------------AQSARDSIVAINPLIEVRLHEFRLESD MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv --------------------------------------------MAGQSD Mb0332|M.bovis_AF2122/97 --------------------------------------------MAGQSD Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu STIGEQRETNYALRAPDKATFIELVTEGQPPAPGYFVYDAILNRKNRGLL MUL_2527|M.ulcerans_Agy99 NAVDLFGHYDLIIDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSV MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS Mb0332|M.bovis_AF2122/97 RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS Mflv_1138|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_6425|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4028|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2562c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5108|M.avium_104 -------------------------------------------------- TH_1234|M.thermoresistible__bu DETALPPVLSYDEMLAAVERGAVLVDGRSPEEFAQGHLRGAINIGLDGRY MUL_2527|M.ulcerans_Agy99 FWEDAPGGLGLNYRDLYPEPPPPGMVPSCAEGGVLGIICASIASVMGTEA MMAR_2139|M.marinum_M -------------------------------------------------- Rv0324|M.tuberculosis_H37Rv ANLQALKSGGLVEARREGTRQYYRIAGEDVAR---LFALVQVVADEHLAD Mb0332|M.bovis_AF2122/97 ANLQALKSGGLVEARREGTRQYYRIAGEDVAR---LFALVQVVADEHLAD Mflv_1138|M.gilvum_PYR-GCK -----------------------------------------------MDD MSMEG_6425|M.smegmatis_MC2_155 -----------------------------------------------MDD Mvan_4028|M.vanbaalenii_PYR-1 -----------------------------------------------MDV MAB_2562c|M.abscessus_ATCC_199 -----------------------------------------MDARQPLYR MAV_5108|M.avium_104 ----------------------------------------MADSRQPLYR TH_1234|M.thermoresistible__bu AEFAGSVLPADVDIVLFTEPGDELEAKNRLAR---IGFDRVIGHLDRPFE MUL_2527|M.ulcerans_Agy99 VKLITGIGETLLGRLMIYDALEMTYRTIRIRKDPATPKITALIDYEQFCG MMAR_2139|M.marinum_M ------------------------------------MPMKIADDAPPTAS Rv0324|M.tuberculosis_H37Rv VAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAI Mb0332|M.bovis_AF2122/97 VAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAI Mflv_1138|M.gilvum_PYR-GCK PDVPQAAISD-----------VPSTFGDGVVLLDVREDDEWQRGHAPQAR MSMEG_6425|M.smegmatis_MC2_155 VEVAKADISA-----------VPTTFDQSVVLLDVREDDEWQRGHVAGAQ Mvan_4028|M.vanbaalenii_PYR-1 LEVDPTGATG-----------LVD--GSGAILLDVREDNEWSAGHAPGAV MAB_2562c|M.abscessus_ATCC_199 MKADFFKTLG---------------HPVRIRVLELLSERDQAVSEMLPEV MAV_5108|M.avium_104 MKAEFFKTLG---------------HPARIRVLELLSSREYAVSEMLPEV TH_1234|M.thermoresistible__bu VMMAHPDRVQVASRLTVKAFDQRAAELPDLQIVDVRNPGEVALGAIPGAI MUL_2527|M.ulcerans_Agy99 VVSDDVARAASDSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQ MMAR_2139|M.marinum_M PREDLAGAVALFHS---------LSDPTRLAIARRLADGERRVVDLTREL : : Rv0324|M.tuberculosis_H37Rv NIP--IAELADRLAELTGDRDIVAYCR---GAYCVMAPDAVRIARDAGRE Mb0332|M.bovis_AF2122/97 NIP--IAELADRLAELAGDRDIVAYCR---GAYCVMAPDAVRIARDAGRE Mflv_1138|M.gilvum_PYR-GCK HIP--MGDVPARLAELDADAELYVVCH---VGGRSQR--VAQYLARNGFR MSMEG_6425|M.smegmatis_MC2_155 HIP--MGEVPARMAEIDPDAELYVICH---AGGRSLR--VANYLARNGYT Mvan_4028|M.vanbaalenii_PYR-1 HVR--LGDLDPR--SFDTTSPVVAVCR---SGNRSGS--AAKKLAAAGVT MAB_2562c|M.abscessus_ATCC_199 GIE--AANLSQQLAVLRRAGLVTARREGLSVLYTLTSPQVAQLLATARTI MAV_5108|M.avium_104 GVE--PANLSQQLSILRRAGLVTARREGLSVRYALTSPQVAELLVVARTI TH_1234|M.thermoresistible__bu AIP--VGQLPDRLTELDPTRPTVVYCA----GGYRSSVAASLLRRSGFTD MUL_2527|M.ulcerans_Agy99 LIPKSLISTGEGLAKLPQDRTTVLYCK----TGVRSAEALAALKKAGFAD MMAR_2139|M.marinum_M GLP--QSTVSSHLACLRDCGLIAGRPEGRQVFYALAVPDLLDLFAAAETV : : Rv0324|M.tuberculosis_H37Rv VKRLDDGMLEWRLAGLPVDEGAPVGHGD--------------- Mb0332|M.bovis_AF2122/97 VKRLDDGMLEWRLAGLPVDEGAPVGHGD--------------- Mflv_1138|M.gilvum_PYR-GCK PVNVTGGMLAWAGAGRPVVTDAGNVGTV--------------- MSMEG_6425|M.smegmatis_MC2_155 PINVEGGMLAWAGAGRPMVTDDGSAGAI--------------- Mvan_4028|M.vanbaalenii_PYR-1 VYNLVGGMKAWREAGRPVIRDDGSAGTVV-------------- MAB_2562c|M.abscessus_ATCC_199 LTGVVADQAEWLDGAGPVPVGPAEATRARR------------- MAV_5108|M.avium_104 LTGVVAGQAETLEEIPESLL--AEPTG---------------- TH_1234|M.thermoresistible__bu VSDILGGYGAWVDARQVA------------------------- MUL_2527|M.ulcerans_Agy99 AAHLQGGIVAWANQMQPDMVMY--------------------- MMAR_2139|M.marinum_M LAATGNAVTLCPNYGTRPTRASASRRRGVKRAAPGVADWSPGR