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M. tuberculosis H37Rv Rv0324 (-)

annotation: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY)
coordinates: 391352 - 392032
length: 226

MAGQSDRKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTASANLQALKSGGLVEA
RREGTRQYYRIAGEDVARLFALVQVVADEHLADVAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRP
HEEYQAGHIPGAINIPIAELADRLAELTGDRDIVAYCRGAYCVMAPDAVRIARDAGREVKRLDDGMLEWR
LAGLPVDEGAPVGHGD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0324--100% (226)POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY)
M. tuberculosis H37RvRv1674c-3e-4545.33% (214) transcriptional regulatory protein
M. tuberculosis H37RvRv3116moeB26e-1034.21% (114) molybdenum cofactor biosynthesis protein MoeB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0332-1e-12499.56% (226) ArsR family transcriptional regulator
M. gilvum PYR-GCKMflv_1138-5e-0840.00% (85) rhodanese domain-containing protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2562c-4e-0831.00% (100) transcriptional regulatory protein ArsR
M. marinum MMMAR_2139-7e-0735.53% (76) transcriptional regulatory protein
M. avium 104MAV_5108-2e-0732.41% (108) transcriptional regulator, ArsR family protein
M. smegmatis MC2 155MSMEG_6425-5e-0832.50% (120) rhodanese-like domain-containing protein
M. thermoresistible (build 8)TH_1234-2e-0848.21% (56) metallo-beta-lactamase family protein
M. ulcerans Agy99MUL_2527moeB11e-0533.33% (111) molybdopterin biosynthesis-like protein MoeZ
M. vanbaalenii PYR-1Mvan_4028-2e-0737.50% (88) rhodanese domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv0324|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0332|M.bovis_AF2122/97            --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      MKFIQYYLDCLSHASYLIADDKTGRAVVVDPQRDVAEYLSDAEKYGYTIE
MUL_2527|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0332|M.bovis_AF2122/97            --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      LVIETHFHADFLSGHLELAEATGAKIVYSSVAETEFESMGVADGERYSLG
MUL_2527|M.ulcerans_Agy99           -----------MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQK
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0332|M.bovis_AF2122/97            --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      DVTLEFLHTPGHTPESLSIVVYEHADDEIPYGVLTGDTLFIGDVGRPDLL
MUL_2527|M.ulcerans_Agy99           RLKNARVLVIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIH
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0332|M.bovis_AF2122/97            --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      ASIGYTREELADKLYDSLHHKLMTLPDATRVYPAHGAGSACGKNLSTELW
MUL_2527|M.ulcerans_Agy99           GVADVGRSK--------------AQSARDSIVAINPLIEVRLHEFRLESD
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         --------------------------------------------MAGQSD
Mb0332|M.bovis_AF2122/97            --------------------------------------------MAGQSD
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      STIGEQRETNYALRAPDKATFIELVTEGQPPAPGYFVYDAILNRKNRGLL
MUL_2527|M.ulcerans_Agy99           NAVDLFGHYDLIIDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSV
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS
Mb0332|M.bovis_AF2122/97            RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS
Mflv_1138|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4028|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2562c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5108|M.avium_104                --------------------------------------------------
TH_1234|M.thermoresistible__bu      DETALPPVLSYDEMLAAVERGAVLVDGRSPEEFAQGHLRGAINIGLDGRY
MUL_2527|M.ulcerans_Agy99           FWEDAPGGLGLNYRDLYPEPPPPGMVPSCAEGGVLGIICASIASVMGTEA
MMAR_2139|M.marinum_M               --------------------------------------------------
                                                                                      

Rv0324|M.tuberculosis_H37Rv         ANLQALKSGGLVEARREGTRQYYRIAGEDVAR---LFALVQVVADEHLAD
Mb0332|M.bovis_AF2122/97            ANLQALKSGGLVEARREGTRQYYRIAGEDVAR---LFALVQVVADEHLAD
Mflv_1138|M.gilvum_PYR-GCK          -----------------------------------------------MDD
MSMEG_6425|M.smegmatis_MC2_155      -----------------------------------------------MDD
Mvan_4028|M.vanbaalenii_PYR-1       -----------------------------------------------MDV
MAB_2562c|M.abscessus_ATCC_199      -----------------------------------------MDARQPLYR
MAV_5108|M.avium_104                ----------------------------------------MADSRQPLYR
TH_1234|M.thermoresistible__bu      AEFAGSVLPADVDIVLFTEPGDELEAKNRLAR---IGFDRVIGHLDRPFE
MUL_2527|M.ulcerans_Agy99           VKLITGIGETLLGRLMIYDALEMTYRTIRIRKDPATPKITALIDYEQFCG
MMAR_2139|M.marinum_M               ------------------------------------MPMKIADDAPPTAS
                                                                                      

Rv0324|M.tuberculosis_H37Rv         VAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAI
Mb0332|M.bovis_AF2122/97            VAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAI
Mflv_1138|M.gilvum_PYR-GCK          PDVPQAAISD-----------VPSTFGDGVVLLDVREDDEWQRGHAPQAR
MSMEG_6425|M.smegmatis_MC2_155      VEVAKADISA-----------VPTTFDQSVVLLDVREDDEWQRGHVAGAQ
Mvan_4028|M.vanbaalenii_PYR-1       LEVDPTGATG-----------LVD--GSGAILLDVREDNEWSAGHAPGAV
MAB_2562c|M.abscessus_ATCC_199      MKADFFKTLG---------------HPVRIRVLELLSERDQAVSEMLPEV
MAV_5108|M.avium_104                MKAEFFKTLG---------------HPARIRVLELLSSREYAVSEMLPEV
TH_1234|M.thermoresistible__bu      VMMAHPDRVQVASRLTVKAFDQRAAELPDLQIVDVRNPGEVALGAIPGAI
MUL_2527|M.ulcerans_Agy99           VVSDDVARAASDSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQ
MMAR_2139|M.marinum_M               PREDLAGAVALFHS---------LSDPTRLAIARRLADGERRVVDLTREL
                                                                   :       :          

Rv0324|M.tuberculosis_H37Rv         NIP--IAELADRLAELTGDRDIVAYCR---GAYCVMAPDAVRIARDAGRE
Mb0332|M.bovis_AF2122/97            NIP--IAELADRLAELAGDRDIVAYCR---GAYCVMAPDAVRIARDAGRE
Mflv_1138|M.gilvum_PYR-GCK          HIP--MGDVPARLAELDADAELYVVCH---VGGRSQR--VAQYLARNGFR
MSMEG_6425|M.smegmatis_MC2_155      HIP--MGEVPARMAEIDPDAELYVICH---AGGRSLR--VANYLARNGYT
Mvan_4028|M.vanbaalenii_PYR-1       HVR--LGDLDPR--SFDTTSPVVAVCR---SGNRSGS--AAKKLAAAGVT
MAB_2562c|M.abscessus_ATCC_199      GIE--AANLSQQLAVLRRAGLVTARREGLSVLYTLTSPQVAQLLATARTI
MAV_5108|M.avium_104                GVE--PANLSQQLSILRRAGLVTARREGLSVRYALTSPQVAELLVVARTI
TH_1234|M.thermoresistible__bu      AIP--VGQLPDRLTELDPTRPTVVYCA----GGYRSSVAASLLRRSGFTD
MUL_2527|M.ulcerans_Agy99           LIPKSLISTGEGLAKLPQDRTTVLYCK----TGVRSAEALAALKKAGFAD
MMAR_2139|M.marinum_M               GLP--QSTVSSHLACLRDCGLIAGRPEGRQVFYALAVPDLLDLFAAAETV
                                     :             :                                  

Rv0324|M.tuberculosis_H37Rv         VKRLDDGMLEWRLAGLPVDEGAPVGHGD---------------
Mb0332|M.bovis_AF2122/97            VKRLDDGMLEWRLAGLPVDEGAPVGHGD---------------
Mflv_1138|M.gilvum_PYR-GCK          PVNVTGGMLAWAGAGRPVVTDAGNVGTV---------------
MSMEG_6425|M.smegmatis_MC2_155      PINVEGGMLAWAGAGRPMVTDDGSAGAI---------------
Mvan_4028|M.vanbaalenii_PYR-1       VYNLVGGMKAWREAGRPVIRDDGSAGTVV--------------
MAB_2562c|M.abscessus_ATCC_199      LTGVVADQAEWLDGAGPVPVGPAEATRARR-------------
MAV_5108|M.avium_104                LTGVVAGQAETLEEIPESLL--AEPTG----------------
TH_1234|M.thermoresistible__bu      VSDILGGYGAWVDARQVA-------------------------
MUL_2527|M.ulcerans_Agy99           AAHLQGGIVAWANQMQPDMVMY---------------------
MMAR_2139|M.marinum_M               LAATGNAVTLCPNYGTRPTRASASRRRGVKRAAPGVADWSPGR