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MTEALIPAPSQISLTRDEVRRYSRHLIIPDIGVNGQQRLKDARVLCIGAGGLGSPALLYLAAAGVGTIGI IDGDHVDESNLQRQIIHGTSDVGRPKVESAAEAVAEINPHVRVTQYREMLTHDNALEIFGDHDLIVDGTD NFTTRYLINDAAVLAGKPYVWGSIYRFNGQTSVFWPGRGPCYRCLHPAPPPPGLVPSCAEGGVLGAICAT IASIQVTEVLKLLTGVGTPLVGRLLMYEALDATYHQIRIAKNPDCAICGDAPTITELVDDSVSCASTQSV DPELVISCDELRTKQQSDQNFLLVDVREPAEFDIAHIPGSILIPKGEIGSAAGLAQLPLDKEIVLYCKSG IRSAQALTTLKAAGLHNVKHLDGGIAEWTRTIDSSLLVY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3116 | moeB2 | - | 100% (389) | PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB2 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) |
| M. tuberculosis H37Rv | Rv3206c | moeB1 | e-122 | 56.27% (391) | molybdopterin biosynthesis-like protein MoeZ |
| M. tuberculosis H37Rv | Rv2338c | moeW | 4e-11 | 34.58% (107) | hypothetical protein Rv2338c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3143 | moeB2 | 0.0 | 100.00% (389) | molybdenum cofactor biosynthesis protein MoeB |
| M. gilvum PYR-GCK | Mflv_4670 | - | 1e-121 | 56.77% (384) | molybdopterin biosynthesis-like protein MoeZ |
| M. leprae Br4923 | MLBr_00817 | moeZ | 1e-121 | 57.55% (384) | molybdopterin biosynthesis-like protein MoeZ |
| M. abscessus ATCC 19977 | MAB_3525c | - | 1e-125 | 58.33% (384) | molybdenum cofactor biosynthesis protein MoeB1 |
| M. marinum M | MMAR_1352 | moeB1 | 1e-123 | 57.29% (398) | molybdenum cofactor biosynthesis protein MoeB1 |
| M. avium 104 | MAV_4153 | - | 1e-119 | 57.62% (387) | molybdopterin biosynthesis-like protein MoeZ |
| M. smegmatis MC2 155 | MSMEG_1937 | - | 1e-122 | 57.29% (384) | molybdopterin biosynthesis-like protein MoeZ |
| M. thermoresistible (build 8) | TH_0450 | moeZ | 1e-122 | 57.81% (384) | PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 |
| M. ulcerans Agy99 | MUL_2527 | moeB1 | 1e-123 | 57.29% (398) | molybdopterin biosynthesis-like protein MoeZ |
| M. vanbaalenii PYR-1 | Mvan_1797 | - | 1e-121 | 56.04% (389) | molybdopterin biosynthesis-like protein MoeZ |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1352|M.marinum_M ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MUL_2527|M.ulcerans_Agy99 ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MLBr_00817|M.leprae_Br4923 -MSTSSTSLPPLVEPAGQLSRDEVIRYSRHLIIPDIGVDGQMRLKSARVL
Mflv_4670|M.gilvum_PYR-GCK ----MSTPLPPLVEPAAELTKEEVARYSRHLIIPDLGLDGQKRLKNARVL
Mvan_1797|M.vanbaalenii_PYR-1 ----MSTPLPPLVEPAAELTREEVARYSRHLIIPDVGLDGQKRLKNARVL
MSMEG_1937|M.smegmatis_MC2_155 MSANLDVSLPPLVEPADELTREEVARYSRHLIIPDLGLDGQKRLKNAKVL
MAB_3525c|M.abscessus_ATCC_199 ----MPT-LPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVL
TH_0450|M.thermoresistible__bu ----VSSPLPPLVEPAAELTREEVARYSRHLIIPDVGVEGQKRLKNARVL
MAV_4153|M.avium_104 ----MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVL
Rv3116|M.tuberculosis_H37Rv ----MTEALIPAPS-QISLTRDEVRRYSRHLIIPDIGVNGQQRLKDARVL
Mb3143|M.bovis_AF2122/97 ----MTEALIPAPS-QISLTRDEVRRYSRHLIIPDIGVNGQQRLKDARVL
* * *: :*: ****:****.:*::** ***.*:**
MMAR_1352|M.marinum_M VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MUL_2527|M.ulcerans_Agy99 VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MLBr_00817|M.leprae_Br4923 VIGAGGLGAPVLLYLAAAGVGTIGIIDFDVVDESNLQRQIIHGVADVGRS
Mflv_4670|M.gilvum_PYR-GCK VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRP
Mvan_1797|M.vanbaalenii_PYR-1 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDLVDESNLQRQIIHGQSDIGRS
MSMEG_1937|M.smegmatis_MC2_155 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
MAB_3525c|M.abscessus_ATCC_199 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
TH_0450|M.thermoresistible__bu VIGAGGLGSPALLYLAAAGVGTLGVIDFDVVDESNLQRQVIHGQADVGRP
MAV_4153|M.avium_104 VIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRS
Rv3116|M.tuberculosis_H37Rv CIGAGGLGSPALLYLAAAGVGTIGIIDGDHVDESNLQRQIIHGTSDVGRP
Mb3143|M.bovis_AF2122/97 CIGAGGLGSPALLYLAAAGVGTIGIIDGDHVDESNLQRQIIHGTSDVGRP
*******:*.***********:*::: * *:*******:*** :*:**.
MMAR_1352|M.marinum_M KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MUL_2527|M.ulcerans_Agy99 KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MLBr_00817|M.leprae_Br4923 KAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGTDNFATR
Mflv_4670|M.gilvum_PYR-GCK KAQSAKDSVLEVNPLVTVNLHEFRLEPDNAVELFEQYDLILDGTDNFATR
Mvan_1797|M.vanbaalenii_PYR-1 KAQSAKDSIAEINPLVNVVLHEFRLEPDNAVDLFAQYDLILDGTDNFATR
MSMEG_1937|M.smegmatis_MC2_155 KAQSARDSIAEINPLVTVNLHEFRLEPDNAVDLFGQYDLILDGTDNFATR
MAB_3525c|M.abscessus_ATCC_199 KAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATR
TH_0450|M.thermoresistible__bu KAESARDTIRAINPFVDVRLHQFRLDRSNAVDLFSEYDLILDGTDNFATR
MAV_4153|M.avium_104 KAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATR
Rv3116|M.tuberculosis_H37Rv KVESAAEAVAEINPHVRVTQYREMLTHDNALEIFGDHDLIVDGTDNFTTR
Mb3143|M.bovis_AF2122/97 KVESAAEAVAEINPHVRVTQYREMLTHDNALEIFGDHDLIVDGTDNFTTR
*. ** ::: :** : * :. * .*.:::* .:***:******:**
MMAR_1352|M.marinum_M YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MUL_2527|M.ulcerans_Agy99 YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MLBr_00817|M.leprae_Br4923 YLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAP-----DGLGLNYRDLY
Mflv_4670|M.gilvum_PYR-GCK YLVNDAAVLAGKPYVWGSIYRFEGQVSIFWEDAP-----NGLGLNYRDLY
Mvan_1797|M.vanbaalenii_PYR-1 YLVNDAAVLAGKPYVWGSIYRFEGQISVFWEDAPADEAGNERGLNYRDLY
MSMEG_1937|M.smegmatis_MC2_155 YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAB_3525c|M.abscessus_ATCC_199 YLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
TH_0450|M.thermoresistible__bu YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----NGQGLNYRDLY
MAV_4153|M.avium_104 YLINDAAVLAGKPYVWGSIYRFEGQASVCWEDAP-----DGRGLNYRDLY
Rv3116|M.tuberculosis_H37Rv YLINDAAVLAGKPYVWGSIYRFNGQTSVFW---P------GRGPCYRCLH
Mb3143|M.bovis_AF2122/97 YLINDAAVLAGKPYVWGSIYRFNGQTSVFW---P------GRGPCYRCLH
**:******* *******:***:** *: * * * ** *:
MMAR_1352|M.marinum_M PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MUL_2527|M.ulcerans_Agy99 PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MLBr_00817|M.leprae_Br4923 LEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIGAPLLGRLMI
Mflv_4670|M.gilvum_PYR-GCK PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDPLLGRLMV
Mvan_1797|M.vanbaalenii_PYR-1 PEPPPPGMVPSCAEGGVLGILCASVGSVMGTEAIKLITGIGETLLGRLMV
MSMEG_1937|M.smegmatis_MC2_155 PEPPPPGMVPSCAEGGVLGILCSSIASIMGTEAIKLITGIGEPLLGRLMV
MAB_3525c|M.abscessus_ATCC_199 PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
TH_0450|M.thermoresistible__bu PEPPPPGMVPSCAEGGVLGILPATIGAIQGTEAIKLITGIGETLLGQLLI
MAV_4153|M.avium_104 PEPPPPGAVPSCAEGGVLGVVCAAIASVMSTEVIKLITGIGESLLGRLMI
Rv3116|M.tuberculosis_H37Rv PAPPPPGLVPSCAEGGVLGAICATIASIQVTEVLKLLTGVGTPLVGRLLM
Mb3143|M.bovis_AF2122/97 PAPPPPGLVPSCAEGGVLGAICATIASIQVTEVLKLLTGVGTPLVGRLLM
***** *********** : :::.:: **.:**:**:* .*:*:*::
MMAR_1352|M.marinum_M YDALEMTYRTIRIRKDP------ATPKITALIDYEQFCG---VVSDDVAR
MUL_2527|M.ulcerans_Agy99 YDALEMTYRTIRIRKDP------ATPKITALIDYEQFCG---VVSDDVAR
MLBr_00817|M.leprae_Br4923 YNALEMSYRRIRIHKDP------SRPKITELTDYQQFCG---VVSDDAAQ
Mflv_4670|M.gilvum_PYR-GCK YDALDMSYRTIKIRKDP------STPKITELIDYEAFCG---VVSDAAAE
Mvan_1797|M.vanbaalenii_PYR-1 YDALDMTYRTIKIRKDP------STPKITELIDYEAFCG---VVSDAAAE
MSMEG_1937|M.smegmatis_MC2_155 YDALDMTYRTIRIRKDP------STPKITELIDYEEFCG---VVSDEAAA
MAB_3525c|M.abscessus_ATCC_199 YDALDMTYRTIKIRKDP------ATPKITELIDYEAFCG---VISDEASA
TH_0450|M.thermoresistible__bu YDALEMSYRKIRIRKDP------STPAITELIDYEEFCG---VVSDAAAE
MAV_4153|M.avium_104 YDALEMSYRTIAIRRDPCD---ASRPAITTLVDYEQLCGAAPAASTDAAT
Rv3116|M.tuberculosis_H37Rv YEALDATYHQIRIAKNPDCAICGDAPTITELVDDSVSCA-------STQS
Mb3143|M.bovis_AF2122/97 YEALDATYHQIRIAKNPDCAICGDAPTITELVDDSVSCA-------STQS
*:**: :*: * * ::* * ** * * . *. .
MMAR_1352|M.marinum_M AASDSTITPQELRAMIDSGKKLALIDVREQVEWDIVHIDGAQLIPKSLIS
MUL_2527|M.ulcerans_Agy99 AASDSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQLIPKSLIS
MLBr_00817|M.leprae_Br4923 VATGSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIPRSLIN
Mflv_4670|M.gilvum_PYR-GCK AAADSTITPRELRELLDSGKPLALIDVREPVEWDINRIEGAELIPKGGFE
Mvan_1797|M.vanbaalenii_PYR-1 AAAESTITPRELRELMDSGKPLALIDVREPVEWDINHIEGAELIPKGAFE
MSMEG_1937|M.smegmatis_MC2_155 AAADSTVTPRELKELLDSGKPLALIDVRERVEWDINHIEGAELIPKPTFE
MAB_3525c|M.abscessus_ATCC_199 AVADSTITPRELRELLDTDKKVALIDVREPVEWDIVHIDGAELVPKSTLE
TH_0450|M.thermoresistible__bu AAADSTVTPRELRELLDAGK-VALVDVREPVEWEINRIEGAELIPKSEIE
MAV_4153|M.avium_104 GGAEAAITPRQLRELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSIN
Rv3116|M.tuberculosis_H37Rv VDPELVISCDELRTKQQSDQNFLLVDVREPAEFDIAHIPGSILIPKGEIG
Mb3143|M.bovis_AF2122/97 VDPELVISCDELRTKQQSDQNFLLVDVREPAEFDIAHIPGSILIPKGEIG
. :: :*: ::. . *:**** .*::* :: *: *:*: :
MMAR_1352|M.marinum_M TGEGLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAVHLQGGIVAWA
MUL_2527|M.ulcerans_Agy99 TGEGLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAAHLQGGIVAWA
MLBr_00817|M.leprae_Br4923 SGEGLAKLPQDRMSVLYCKTGVRSAETLATVKKAGFSDAVHLQGGIVAWA
Mflv_4670|M.gilvum_PYR-GCK SGEALSKLDNDRTPVFYCKTGIRSAEVLAIVKKAGFADAMHVQGGIVAWG
Mvan_1797|M.vanbaalenii_PYR-1 SGEALSKLKVDRTPVFYCKTGIRSAEVLAIVKKAGFSDAMHVQGGIVAWG
MSMEG_1937|M.smegmatis_MC2_155 SGAALAKLPTDRTPVFYCKTGVRSAEVLAIAKKAGFSDAVHLQGGIVAWA
MAB_3525c|M.abscessus_ATCC_199 SGDGLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWA
TH_0450|M.thermoresistible__bu SGVGLAKLPMDRAPVLYCKTGVRSAEALAAVKRAGFADAMHLQGGIVAWA
MAV_4153|M.avium_104 SGEGLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWA
Rv3116|M.tuberculosis_H37Rv SAAGLAQLPLDKEIVLYCKSGIRSAQALTTLKAAGLHNVKHLDGGIAEWT
Mb3143|M.bovis_AF2122/97 SAAGLAQLPLDKEIVLYCKSGIRSAQALTTLKAAGLHNVKHLDGGIAEWT
:. .*::* *: *:***:*:***:.*. : **: :. *::***. *
MMAR_1352|M.marinum_M NQMQPDMVMY
MUL_2527|M.ulcerans_Agy99 NQMQPDMVMY
MLBr_00817|M.leprae_Br4923 KQVQPDMVIY
Mflv_4670|M.gilvum_PYR-GCK KQLEPDMVMY
Mvan_1797|M.vanbaalenii_PYR-1 KQLEPDMVMY
MSMEG_1937|M.smegmatis_MC2_155 KQLEPDMVMY
MAB_3525c|M.abscessus_ATCC_199 KQVDPDMVMY
TH_0450|M.thermoresistible__bu KQLEPDMVMY
MAV_4153|M.avium_104 QQMQPDMILY
Rv3116|M.tuberculosis_H37Rv RTIDSSLLVY
Mb3143|M.bovis_AF2122/97 RTIDSSLLVY
. ::..:::*