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PNRRRRKLSTAMSAVAALAVASPCAYFLVYESTAGNKAPEHHEFKQAAVMSDLPGELMGALSQGLSQFGI NLPPVPALSGGATSTPGLASPGLGSPGLGSPGLGTPGLGTPGLTNPGLTSPGATSPGLTSPGLTSPGLTS PGLTSPGAAPTTPGLTAPGALPTTPGGGVATPGAGLNPALSNPGLTSPAGTAPGLGSPTVAPSEVPIDSG AGLDPGAGGTYPILGDPSTFGNASPIGGGGTGLGGGSSSGGSGGLVNDVMQAANQLGAGQAIDLLKGLVM PAITQGMHGGAAAGALPGAAGALPGAAGALPGAAGALPGAAGALPAAAGAAGALPAAAGAAPALPPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0207 | - | - | 100% (348) | Erp protein |
| M. avium 104 | MAV_4827 | - | 2e-13 | 36.95% (203) | hypothetical protein MAV_4827 |
| M. avium 104 | MAV_0278 | - | 4e-11 | 27.61% (326) | hypothetical protein MAV_0278 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3840 | pirG | 5e-82 | 55.31% (320) | exported repetitive protein precursor PirG (cell surface |
| M. gilvum PYR-GCK | Mflv_1158 | - | 3e-74 | 51.59% (345) | repeat of unknown function XGLTT |
| M. tuberculosis H37Rv | Rv3810 | pirG | 5e-82 | 55.31% (320) | exported repetitive protein precursor PirG (cell surface |
| M. leprae Br4923 | MLBr_00091 | - | 4e-54 | 44.73% (313) | 28 KDa antigen precursor |
| M. abscessus ATCC 19977 | MAB_0169c | - | 7e-61 | 49.20% (313) | putative exported repetitive protein precursor |
| M. marinum M | MMAR_5374 | erp | 1e-90 | 58.02% (343) | exported repetitive protein precursor Erp |
| M. smegmatis MC2 155 | MSMEG_6405 | - | 1e-82 | 56.31% (325) | Erp protein |
| M. thermoresistible (build 8) | TH_2084 | - | 6e-76 | 52.47% (324) | Erp protein |
| M. ulcerans Agy99 | MUL_4994 | erp | 1e-95 | 59.72% (355) | exported repetitive protein precursor Erp |
| M. vanbaalenii PYR-1 | Mvan_5651 | - | 3e-76 | 51.03% (341) | exported repetitive protein precursor PirG (cell surface |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1158|M.gilvum_PYR-GCK MPNRRRRRLSTALSTVAALAVASPIAVIAVSELSASTLAGRDGAPQHREF
Mvan_5651|M.vanbaalenii_PYR-1 MPNRRRRRLSTALSTVAALAVASPVAVVAITELSAE--PGRDGAPQHREF
MSMEG_6405|M.smegmatis_MC2_155 MPNRRRRKLSTAMSAVAAVAVASPVALIAATQHS--------PAPQHREF
TH_2084|M.thermoresistible__bu ------------MSTVAALAVASPFAAIAVTELVSS----TQPAPQQREF
Mb3840|M.bovis_AF2122/97 MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTET----TERPE-HHEF
Rv3810|M.tuberculosis_H37Rv MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTET----TERPE-HHEF
MMAR_5374|M.marinum_M ------------MSAVAALAVASPCAYFLVYESTTE----TKPTE-HHEF
MUL_4994|M.ulcerans_Agy99 MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTTE----TKPTE-HHEF
MLBr_00091|M.leprae_Br4923 MPNRRRCKLSTAISTVATLAIASPCAYFLVYEPTAS----AKPAAKHYEF
MAV_0207|M.avium_104 MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTAG----NKAPE-HHEF
MAB_0169c|M.abscessus_ATCC_199 MPNRRRRRLSTALSSVAALAVASPFAIALATNMTQA----AAPAPSQQEF
:*:**::*:*** * : . : **
Mflv_1158|M.gilvum_PYR-GCK VQAATITDLPGELMTALSQGLAQFGINLPPLPTGLLTGT-----------
Mvan_5651|M.vanbaalenii_PYR-1 VQAATITDLPGELFNALSQGLSQFGINLPPMPTGLLTGS-----------
MSMEG_6405|M.smegmatis_MC2_155 TQAALVTDLPGELMSALSQGLSQFGINLPPMPS--LTGG--AAT------
TH_2084|M.thermoresistible__bu VQASLLTDLPTELMGALSEGLAQFGINLPPMPS--LTGSGASMS------
Mb3840|M.bovis_AF2122/97 KQAAVLTDLPGELMSALSQGLSQFGINIPPVPS--LTG------------
Rv3810|M.tuberculosis_H37Rv KQAAVLTDLPGELMSALSQGLSQFGINIPPVPS--LTG------------
MMAR_5374|M.marinum_M VRAASVADLPTELMTALSQGLSSFGINLPPVPS--LTGGTGTGM------
MUL_4994|M.ulcerans_Agy99 VRAASVADLPTELMTALSQGLSSFGINLPPVPS--LTGGTGTGM------
MLBr_00091|M.leprae_Br4923 KQAASIADLPGEVLDAISQGLSQFGINLPPVPS--LTG------------
MAV_0207|M.avium_104 KQAAVMSDLPGELMGALSQGLSQFGINLPPVPA--LSGGATSTPGLASPG
MAB_0169c|M.abscessus_ATCC_199 VQAAIVSDLPGEVMGAVQQMTSQFGVQIPGLSGLNIPGLG----------
:*: ::*** *:: *:.: :.**:::* :. :.*
Mflv_1158|M.gilvum_PYR-GCK ----GAAAPTTLSPGLGTAGLTSPGLMPGL--SAAPSLTDPS--LAN---
Mvan_5651|M.vanbaalenii_PYR-1 ----GATSPTTLSPGLGFPSLASPGLTTPG--LTAPTLTDPG--LANPAL
MSMEG_6405|M.smegmatis_MC2_155 ---PSLASPTLTSPGLASPGLTSPGLT-PG--LT-PGLTTPS--LTDPGL
TH_2084|M.thermoresistible__bu ---PGLTSPGLTSPGLTSPGLTSPGLTSPG--LTSPGLTSPG--LTNPGL
Mb3840|M.bovis_AF2122/97 -------------SGDASTGLTGPGLTSPG--LTSPGLTSPG--LTDPAL
Rv3810|M.tuberculosis_H37Rv -------------SGDASTGLTGPGLTSPG--LTSPGLTSPG--LTDPAL
MMAR_5374|M.marinum_M ------------SPGLTSPGLTSPGLTSPG--LTSPGLTTPG--LTSPGL
MUL_4994|M.ulcerans_Agy99 ------------SPGLTSPGLTSPGLTSPG--LTSPGLTSPG--LTSPGL
MLBr_00091|M.leprae_Br4923 -------------TDDPGNGLRTPGLTSPD--LTNQELGTPV--LTAPG-
MAV_0207|M.avium_104 LGSPGLGSPGLGTPGLGTPGLTNPGLTSPG--ATSPGLTSPG--LTSPGL
MAB_0169c|M.abscessus_ATCC_199 ------------GGGLGSLGGANPALTSPGGLTTPGGLTSPSSSLTNPAL
. . *.* : * * *:
Mflv_1158|M.gilvum_PYR-GCK --PALTSPIGATP-GLTTPGLTTPGLTTPGLTDPALA----SPGLTTPAL
Mvan_5651|M.vanbaalenii_PYR-1 TNPALTSPTGAAP-GLTTPGLTTPGLTTPGLTDPALA----SPGLTTPSL
MSMEG_6405|M.smegmatis_MC2_155 TNPALTNPALTSPDGLTSPGLTTPSLTSPGLTTPDAS-LGATPSLTDPGL
TH_2084|M.thermoresistible__bu TSPGLTDPALTTP-GLTTPGLTTPGLTTPGLTTPGLDPAQTTPGLTTPGV
Mb3840|M.bovis_AF2122/97 TSPGLTPT-------------LPGSLAAPGTTLAPTPGVGANPALTNPAL
Rv3810|M.tuberculosis_H37Rv TSPGLTPT-------------LPGSLAAPGTTLAPTPGVGANPALTNPAL
MMAR_5374|M.marinum_M TTPGLTPG-------------MPGDLALPGTTLPPTPGAAVNPALTNPAL
MUL_4994|M.ulcerans_Agy99 TTPGLTPG-------------MPGDLALPGTTLPPTPGAAVNPALTNPAL
MLBr_00091|M.leprae_Br4923 --TGLTPP-------------VTG-----------------SPICTAPDL
MAV_0207|M.avium_104 TSPGLTSPGAAPT---TPGLTAPGALPTTPGGGVATPGAGLNPALSNPGL
MAB_0169c|M.abscessus_ATCC_199 TNPGLTSPSGSTT-----PSLTDPALTNPGLTNPAAP--ASTPGLTPAAG
..** .* : .
Mflv_1158|M.gilvum_PYR-GCK TDPGLTTPGLTTPGLTTP--GLTTP--GLTTPAALTDPALGLPATGEIPI
Mvan_5651|M.vanbaalenii_PYR-1 TDPALASPGLTTPGLSTPP-ALTDP--ALG-ALPISTSGLG---TGEVPI
MSMEG_6405|M.smegmatis_MC2_155 TNPALTTPSLTTPGLATPSTGLTTP--GLDPSLTPISNAAGLPAPGEVPI
TH_2084|M.thermoresistible__bu STPDLTNPALTSP-LGEAPGGLTTPSVGLDPALTPISNTAGLPAPGEVPI
Mb3840|M.bovis_AF2122/97 TSPTGATPGLTSPTGLDPA----------------------LGGANEIPI
Rv3810|M.tuberculosis_H37Rv TSPTGATPGLTSPTGLDPA----------------------LGGANEIPI
MMAR_5374|M.marinum_M TSPTGLAPGLTSPTGLDPS----------------------LGGTNEIPI
MUL_4994|M.ulcerans_Agy99 TSPTGLAPGLTSPTGLDPS----------------------LGGTNEIPI
MLBr_00091|M.leprae_Br4923 N------LGGTCPS--------------------------------EVPI
MAV_0207|M.avium_104 TSPAGTAPGLGSPT----------------------------VAPSEVPI
MAB_0169c|M.abscessus_ATCC_199 TGATGVNPALTDPAAGLTS------------------------PGGEVPI
. . * *:**
Mflv_1158|M.gilvum_PYR-GCK SAPIGLDP-ALGSYPILGDP-SLAATQP----------VATSSGG--LLG
Mvan_5651|M.vanbaalenii_PYR-1 SAPIGLDP-ALGSYPVLGDP-SLAATQP----------VASSSGG--LLG
MSMEG_6405|M.smegmatis_MC2_155 SAPVGLDP-SLGTYPILGDP-SLATMP------------AASTGGGGLFG
TH_2084|M.thermoresistible__bu TAPLGPDP-TLGTYPILGDP-SLAMAPP----------VATSTGGGGLIS
Mb3840|M.bovis_AF2122/97 TTPVGLDPGADGTYPILGDP-TLGTIP--SSPAT------TSTGGGGLVN
Rv3810|M.tuberculosis_H37Rv TTPVGLDPGADGTYPILGDP-TLGTIP--SSPAT------TSTGGGGLVN
MMAR_5374|M.marinum_M TTPVGLDPGMDGTYPILGDP-SLGYGP--GTSSLGGSGLGSSTGGGGILN
MUL_4994|M.ulcerans_Agy99 TTPVGLDPGMDGTYPILGDP-SLGYGP--GTSSLGGSGLGSSTGGG-ILN
MLBr_00091|M.leprae_Br4923 TTPISLDPGTDGTYPILGDPSTLG-----GTSPI-------STSSGELVN
MAV_0207|M.avium_104 DSGAGLDPGAGGTYPILGDPSTFGNASPIGGGGTGLGGGSSSGGSGGLVN
MAB_0169c|M.abscessus_ATCC_199 TPNPALGT--GLTNPALADP-SLAGLG----TPTGLGGGSGLGGGSSLIS
. . .. : * *.** ::. .. :..
Mflv_1158|M.gilvum_PYR-GCK DLTSAANSLGAGEAIDLLKGVLMPAIMSAVKPPVPPVPAAPLATAAGEV-
Mvan_5651|M.vanbaalenii_PYR-1 DLSSAANSLGAGEAIDLLKGVLMPAIMSAVKPPAP-LPAAPVAQAAGTVP
MSMEG_6405|M.smegmatis_MC2_155 DLSAAADQLGAGQAIDLLKGMVLPAITQAIQSGAQ-AAPAAAPAP---VP
TH_2084|M.thermoresistible__bu ELSTAANQLGAGQAIDLLKGVVMPAVTSAIKSAAQPPGPDVAPPPAPEVP
Mb3840|M.bovis_AF2122/97 DVMQVANELGASQAIDLLKGVLMPSIMQAVQNGGAAAPAASPPVPPIPAA
Rv3810|M.tuberculosis_H37Rv DVMQVANELGASQAIDLLKGVLMPSIMQAVQNGGAAAPAASPPVPPIPAA
MMAR_5374|M.marinum_M DVMQAANQLGAGQAIDLLKGVLMPSIMQAVQNGGAAAPAAAAAVPELPAA
MUL_4994|M.ulcerans_Agy99 DVMQAANQLGAGQAIDLLKGVLVSSIMQAVQNGGAAAPAAAAAVPELPAA
MLBr_00091|M.leprae_Br4923 DLLKVANQLGASQVMDLIKGVVMPAVMQGVQNGNVAGDLSGSVTP--AAI
MAV_0207|M.avium_104 DVMQAANQLGAGQAIDLLKGLVMPAITQGMHGGAAAGALPGAAGALPGAA
MAB_0169c|M.abscessus_ATCC_199 DAMGAVNQLGITQAVDLIKGAIPAAASAAAPPPAS---------------
: ..:.** :.:**:** : .: .
Mflv_1158|M.gilvum_PYR-GCK APVEAG------------LGAAEASFETGAEPGA------
Mvan_5651|M.vanbaalenii_PYR-1 AEAEAA------------LGAAEAAIEPGA----------
MSMEG_6405|M.smegmatis_MC2_155 PPA-------------------------------------
TH_2084|M.thermoresistible__bu APDA------------------------------------
Mb3840|M.bovis_AF2122/97 AAVP--------------PTDP--ITVPVA----------
Rv3810|M.tuberculosis_H37Rv AAVP--------------PTDP--ITVPVA----------
MMAR_5374|M.marinum_M AAAP--------------AAAAPAAVAPAAAAAAAAVPPI
MUL_4994|M.ulcerans_Agy99 AAAP--------------AAAAPAAVAPAAAAAAAAVPPI
MLBr_00091|M.leprae_Br4923 SLIP--------------VT--------------------
MAV_0207|M.avium_104 GALPGAAGALPGAAGALPAAAGAAGALPAAAGAAPALPPV
MAB_0169c|M.abscessus_ATCC_199 ----------------------------------------