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TQPSGLKNLLRAAAGALPVVPRTDQLPNRTVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPS VMSLVTGFDFPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTNVSVGNDVAWHQ VTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAKIRRYAAVGGDHNPIHTNPIAAKLFGFPTVIA HGMFTAAAVLANIEARFPDAVRYSVRFAKPVLLPATAGLYVAEGDGGWDLTLRNMAKGYPHLTATVRGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0241c | - | - | 100% (280) | hypothetical protein Rv0241c |
| M. tuberculosis H37Rv | Rv2524c | fas | 6e-07 | 52.38% (42) | fatty acid synthase |
| M. tuberculosis H37Rv | Rv0636 | - | 5e-06 | 35.44% (79) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0247c | - | 1e-162 | 100.00% (280) | hypothetical protein Mb0247c |
| M. gilvum PYR-GCK | Mflv_0413 | - | 1e-125 | 76.98% (278) | dehydratase |
| M. leprae Br4923 | MLBr_02566 | - | 1e-136 | 82.14% (280) | hypothetical protein MLBr_02566 |
| M. abscessus ATCC 19977 | MAB_4444 | - | 2e-99 | 60.42% (283) | hypothetical protein MAB_4444 |
| M. marinum M | MMAR_0502 | - | 1e-140 | 84.10% (283) | hypothetical protein MMAR_0502 |
| M. avium 104 | MAV_4917 | - | 1e-137 | 83.57% (280) | MaoC like domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0371 | - | 1e-128 | 78.85% (279) | MaoC like domain-containing protein |
| M. thermoresistible (build 8) | TH_1913 | - | 1e-118 | 74.54% (271) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1165 | - | 1e-139 | 83.75% (283) | hypothetical protein MUL_1165 |
| M. vanbaalenii PYR-1 | Mvan_0258 | - | 1e-128 | 78.78% (278) | dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0413|M.gilvum_PYR-GCK ---------------MSD---KQPSGLKNLALAAAGALPFVPRGDTLPTR
Mvan_0258|M.vanbaalenii_PYR-1 ---------------MNES--KQPSGLKNLALAVAGALPLVPRGDTLPTR
MSMEG_0371|M.smegmatis_MC2_155 ---------------MADTQTTQPSGLKNMARAVVGALPFVTRSESLPKR
Rv0241c|M.tuberculosis_H37Rv --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
Mb0247c|M.bovis_AF2122/97 --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
MMAR_0502|M.marinum_M --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
MUL_1165|M.ulcerans_Agy99 --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
MLBr_02566|M.leprae_Br4923 MTFGFVLRRLRRHFSVKENTVNQPSGLKNILRAIVGALPLLPRTDQLPSR
MAV_4917|M.avium_104 -------------------MMNQPSGLKNMLCAAAGALPVVSRGSALPTR
TH_1913|M.thermoresistible__bu -----------------------------MVRAAAGALPVVRRDGTLPKR
MAB_4444|M.abscessus_ATCC_1997 --------------------MAQPSGLQNMVMAAVGALPFIPRPSTLPTR
: * .****.: * **.*
Mflv_0413|M.gilvum_PYR-GCK TLTVEDLSIDPVNVAEYADVTGLRFDNTVPLTYPFALTFPTVMQLITGFD
Mvan_0258|M.vanbaalenii_PYR-1 TLTVEDLTIDPVNVAEYANVTGLRFGNTVPLTYPFALTFPTVMALLTGFD
MSMEG_0371|M.smegmatis_MC2_155 TVTVDDLTIDPANVAEYAQVTGLRFGDAVPLTYPFTLTFPAVMSLVTGLD
Rv0241c|M.tuberculosis_H37Rv TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
Mb0247c|M.bovis_AF2122/97 TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
MMAR_0502|M.marinum_M TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
MUL_1165|M.ulcerans_Agy99 TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
MLBr_02566|M.leprae_Br4923 TVTIEELPIDHTNVSAYASVTGLRYGNHVPLTYPFALTFPAMMSLVTGFD
MAV_4917|M.avium_104 TVTVEDLPIDRTNVAEYAAVTGLRYRNHVPLTYPFALTFPALMSLVTGFD
TH_1913|M.thermoresistible__bu TVTATDLPIDAAHVADYAAVTGLLFRDQVPLTYPFALTFPHVMELLSGFD
MAB_4444|M.abscessus_ATCC_1997 VVRTQGVKIDPANVAAYAQVTGLTFSDKVPVTYPFTLQFPSVMSLVASLD
.: : ** .:*: ** **** : : **:****.* ** :* *::.:*
Mflv_0413|M.gilvum_PYR-GCK FPFAAMGSVHLENHITQLRPIAVTDTVSVAVHAENMREHRRGLLVDILTD
Mvan_0258|M.vanbaalenii_PYR-1 FPFAAMGSVHLENHITQYRPIAVTDTVSVGVHAENMREHRRGLLVDVVTD
MSMEG_0371|M.smegmatis_MC2_155 FPFAAMGSVHIENHITQYRPIAVTDTVGVAVHAENLREHRRGLLVDIVTD
Rv0241c|M.tuberculosis_H37Rv FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
Mb0247c|M.bovis_AF2122/97 FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
MMAR_0502|M.marinum_M FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
MUL_1165|M.ulcerans_Agy99 FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
MLBr_02566|M.leprae_Br4923 FPFAAMGSVHTENHITQYRPIAVTDVVGVQVHAENLREHRKGLLVDLVTD
MAV_4917|M.avium_104 FPFAAMGSVHTENHITQYRPIAVTDTVGVRVHAENLREHRKGLLVDLVTD
TH_1913|M.thermoresistible__bu FPFPAIGAVHVENHITQQRPILVTDIVNISVHAENLREHRRGLLVDLVTD
MAB_4444|M.abscessus_ATCC_1997 FPFPAIGTVHLENHITQHRAISATDTVDIEVRAENLREHRKGLLVDVLTD
***.*:*::* ****** *.* .** *.: *:***:****:**:**::*:
Mflv_0413|M.gilvum_PYR-GCK VRVGNELAWQQVTTFLHQQRTSLSDEPKPPPQKQPKLPPPNAVLRITPAQ
Mvan_0258|M.vanbaalenii_PYR-1 VKVGNDPAWHQITTFLHQQRTSLSDQPKPPPQKQPKLPPPNAVLRITPAQ
MSMEG_0371|M.smegmatis_MC2_155 VKVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPNAVLRITPGQ
Rv0241c|M.tuberculosis_H37Rv VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
Mb0247c|M.bovis_AF2122/97 VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
MMAR_0502|M.marinum_M INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
MUL_1165|M.ulcerans_Agy99 INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
MLBr_02566|M.leprae_Br4923 VSVGNDTAWHQVTTFLHLQRTSLSDEPKPPSQKQPKLLPPSAVLQITPRQ
MAV_4917|M.avium_104 VSVGNDTAWHQVTTFLHQQRTSLSDQPKPPPQKQPKLPPPPTVLRITPGL
TH_1913|M.thermoresistible__bu IYVGNEAAWHQVSTFLHQQRTSLSDEPKPPPAKQPKLGPPNAVLRVTPGQ
MAB_4444|M.abscessus_ATCC_1997 ITIGTDTVWQQTMTFLRQQRTSLSGGPKPEPPKAVKLPPPNSTLRISGGQ
: :*.: .*:* ***: ******. *** . * ** ** :.*:::
Mflv_0413|M.gilvum_PYR-GCK IKHYASVGGDHNPIHTNGIAARLFGFPTVIAHGMFTAAAVLANVEGQLPD
Mvan_0258|M.vanbaalenii_PYR-1 IRHYASVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLPD
MSMEG_0371|M.smegmatis_MC2_155 IRHYAAVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLSD
Rv0241c|M.tuberculosis_H37Rv IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
Mb0247c|M.bovis_AF2122/97 IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
MMAR_0502|M.marinum_M IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
MUL_1165|M.ulcerans_Agy99 IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
MLBr_02566|M.leprae_Br4923 IRRYAAVGGDHNPIHTNPIVAKLFGFPTTIAHGMFSAAAVLANIEARLPD
MAV_4917|M.avium_104 IRRYAVVGGDHNPIHTNPIAAKLFGFPTVIAHGMFSAAAVLANIEAAIPD
TH_1913|M.thermoresistible__bu IRRYASVGGDHNPIHTSSLGAKLFGFPTVIAHGMYTAAAVLANIEGRLPD
MAB_4444|M.abscessus_ATCC_1997 IRRYASVGGDHNPIHTSSIGAKALGFPKAIAHGMFTAAAVLGNIQGDIPD
*::** **********. : *: :***..*****::*****.*::. :.*
Mflv_0413|M.gilvum_PYR-GCK GVKYSVRFAKPVILPARAGLYVDRRAD---GWDLTLRHLTKGHPHLTGTL
Mvan_0258|M.vanbaalenii_PYR-1 AVKYSVRFAKPVVLPARAGLYVDRSAD---AWELTLRHLTKGYPHLQATV
MSMEG_0371|M.smegmatis_MC2_155 AVKHSVRFAKPVVLPAKAALYVERDAD---GWELTLRHLTKGYPHLTATV
Rv0241c|M.tuberculosis_H37Rv AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
Mb0247c|M.bovis_AF2122/97 AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
MMAR_0502|M.marinum_M AVRYSVRFGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
MUL_1165|M.ulcerans_Agy99 AVRYSVRLGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
MLBr_02566|M.leprae_Br4923 AVHYSARFVKPVVLPATTGLYVDESAG---NWDLTLRNIAKGYPHLAGTV
MAV_4917|M.avium_104 AVRYSVRFGKPVVLPATTGLYIDEHDG---GWDIALRNIAKGYPHLTGTV
TH_1913|M.thermoresistible__bu AVRYSVRFGKPLVLPAAAGLYVQQTDG---GWELALRHLTKGYPHLTAMV
MAB_4444|M.abscessus_ATCC_1997 AVRYDVKFGKPVLLPAAVGVWIDRPGGPGTAWDIAVRNPRNGDPHVTGSV
.*::..:: **::*** ..::: . *::::*: :* **: . :
Mflv_0413|M.gilvum_PYR-GCK TSL-
Mvan_0258|M.vanbaalenii_PYR-1 TSLR
MSMEG_0371|M.smegmatis_MC2_155 TPL-
Rv0241c|M.tuberculosis_H37Rv RGL-
Mb0247c|M.bovis_AF2122/97 RGL-
MMAR_0502|M.marinum_M KPL-
MUL_1165|M.ulcerans_Agy99 KPL-
MLBr_02566|M.leprae_Br4923 QGV-
MAV_4917|M.avium_104 RAL-
TH_1913|M.thermoresistible__bu TPL-
MAB_4444|M.abscessus_ATCC_1997 TPL-
: