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NESKQPSGLKNLALAVAGALPLVPRGDTLPTRTLTVEDLTIDPVNVAEYANVTGLRFGNTVPLTYPFALT FPTVMALLTGFDFPFAAMGSVHLENHITQYRPIAVTDTVSVGVHAENMREHRRGLLVDVVTDVKVGNDPA WHQITTFLHQQRTSLSDQPKPPPQKQPKLPPPNAVLRITPAQIRHYASVGGDHNPIHTNAIAAKLFGFPT VIAHGMFSAAAVLANIEGQLPDAVKYSVRFAKPVVLPARAGLYVDRSADAWELTLRHLTKGYPHLQATVT SLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0258 | - | - | 100% (284) | dehydratase |
| M. vanbaalenii PYR-1 | Mvan_5844 | - | 2e-09 | 36.90% (84) | dehydratase |
| M. vanbaalenii PYR-1 | Mvan_4125 | - | 1e-08 | 29.41% (238) | dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0247c | - | 1e-128 | 78.78% (278) | hypothetical protein Mb0247c |
| M. gilvum PYR-GCK | Mflv_0413 | - | 1e-147 | 88.89% (279) | dehydratase |
| M. tuberculosis H37Rv | Rv0241c | - | 1e-128 | 78.78% (278) | hypothetical protein Rv0241c |
| M. leprae Br4923 | MLBr_02566 | - | 1e-126 | 76.70% (279) | hypothetical protein MLBr_02566 |
| M. abscessus ATCC 19977 | MAB_4444 | - | 1e-100 | 60.14% (281) | hypothetical protein MAB_4444 |
| M. marinum M | MMAR_0502 | - | 1e-128 | 77.66% (282) | hypothetical protein MMAR_0502 |
| M. avium 104 | MAV_4917 | - | 1e-128 | 78.78% (278) | MaoC like domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0371 | - | 1e-140 | 84.34% (281) | MaoC like domain-containing protein |
| M. thermoresistible (build 8) | TH_1913 | - | 1e-118 | 75.00% (268) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1165 | - | 1e-127 | 77.30% (282) | hypothetical protein MUL_1165 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0258|M.vanbaalenii_PYR-1 ---------------MNES--KQPSGLKNLALAVAGALPLVPRGDTLPTR
Mflv_0413|M.gilvum_PYR-GCK ---------------MSD---KQPSGLKNLALAAAGALPFVPRGDTLPTR
MSMEG_0371|M.smegmatis_MC2_155 ---------------MADTQTTQPSGLKNMARAVVGALPFVTRSESLPKR
MMAR_0502|M.marinum_M --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
MUL_1165|M.ulcerans_Agy99 --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
Mb0247c|M.bovis_AF2122/97 --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
Rv0241c|M.tuberculosis_H37Rv --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
MLBr_02566|M.leprae_Br4923 MTFGFVLRRLRRHFSVKENTVNQPSGLKNILRAIVGALPLLPRTDQLPSR
MAV_4917|M.avium_104 -------------------MMNQPSGLKNMLCAAAGALPVVSRGSALPTR
TH_1913|M.thermoresistible__bu -----------------------------MVRAAAGALPVVRRDGTLPKR
MAB_4444|M.abscessus_ATCC_1997 --------------------MAQPSGLQNMVMAAVGALPFIPRPSTLPTR
: * .****.: * **.*
Mvan_0258|M.vanbaalenii_PYR-1 TLTVEDLTIDPVNVAEYANVTGLRFGNTVPLTYPFALTFPTVMALLTGFD
Mflv_0413|M.gilvum_PYR-GCK TLTVEDLSIDPVNVAEYADVTGLRFDNTVPLTYPFALTFPTVMQLITGFD
MSMEG_0371|M.smegmatis_MC2_155 TVTVDDLTIDPANVAEYAQVTGLRFGDAVPLTYPFTLTFPAVMSLVTGLD
MMAR_0502|M.marinum_M TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
MUL_1165|M.ulcerans_Agy99 TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
Mb0247c|M.bovis_AF2122/97 TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
Rv0241c|M.tuberculosis_H37Rv TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
MLBr_02566|M.leprae_Br4923 TVTIEELPIDHTNVSAYASVTGLRYGNHVPLTYPFALTFPAMMSLVTGFD
MAV_4917|M.avium_104 TVTVEDLPIDRTNVAEYAAVTGLRYRNHVPLTYPFALTFPALMSLVTGFD
TH_1913|M.thermoresistible__bu TVTATDLPIDAAHVADYAAVTGLLFRDQVPLTYPFALTFPHVMELLSGFD
MAB_4444|M.abscessus_ATCC_1997 VVRTQGVKIDPANVAAYAQVTGLTFSDKVPVTYPFTLQFPSVMSLVASLD
.: : ** .:*: ** **** : : **:****.* ** :* *::.:*
Mvan_0258|M.vanbaalenii_PYR-1 FPFAAMGSVHLENHITQYRPIAVTDTVSVGVHAENMREHRRGLLVDVVTD
Mflv_0413|M.gilvum_PYR-GCK FPFAAMGSVHLENHITQLRPIAVTDTVSVAVHAENMREHRRGLLVDILTD
MSMEG_0371|M.smegmatis_MC2_155 FPFAAMGSVHIENHITQYRPIAVTDTVGVAVHAENLREHRRGLLVDIVTD
MMAR_0502|M.marinum_M FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
MUL_1165|M.ulcerans_Agy99 FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
Mb0247c|M.bovis_AF2122/97 FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
Rv0241c|M.tuberculosis_H37Rv FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
MLBr_02566|M.leprae_Br4923 FPFAAMGSVHTENHITQYRPIAVTDVVGVQVHAENLREHRKGLLVDLVTD
MAV_4917|M.avium_104 FPFAAMGSVHTENHITQYRPIAVTDTVGVRVHAENLREHRKGLLVDLVTD
TH_1913|M.thermoresistible__bu FPFPAIGAVHVENHITQQRPILVTDIVNISVHAENLREHRRGLLVDLVTD
MAB_4444|M.abscessus_ATCC_1997 FPFPAIGTVHLENHITQHRAISATDTVDIEVRAENLREHRKGLLVDVLTD
***.*:*::* ****** *.* .** *.: *:***:****:**:**::*:
Mvan_0258|M.vanbaalenii_PYR-1 VKVGNDPAWHQITTFLHQQRTSLSDQPKPPPQKQPKLPPPNAVLRITPAQ
Mflv_0413|M.gilvum_PYR-GCK VRVGNELAWQQVTTFLHQQRTSLSDEPKPPPQKQPKLPPPNAVLRITPAQ
MSMEG_0371|M.smegmatis_MC2_155 VKVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPNAVLRITPGQ
MMAR_0502|M.marinum_M INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
MUL_1165|M.ulcerans_Agy99 INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
Mb0247c|M.bovis_AF2122/97 VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
Rv0241c|M.tuberculosis_H37Rv VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
MLBr_02566|M.leprae_Br4923 VSVGNDTAWHQVTTFLHLQRTSLSDEPKPPSQKQPKLLPPSAVLQITPRQ
MAV_4917|M.avium_104 VSVGNDTAWHQVTTFLHQQRTSLSDQPKPPPQKQPKLPPPPTVLRITPGL
TH_1913|M.thermoresistible__bu IYVGNEAAWHQVSTFLHQQRTSLSDEPKPPPAKQPKLGPPNAVLRVTPGQ
MAB_4444|M.abscessus_ATCC_1997 ITIGTDTVWQQTMTFLRQQRTSLSGGPKPEPPKAVKLPPPNSTLRISGGQ
: :*.: .*:* ***: ******. *** . * ** ** :.*:::
Mvan_0258|M.vanbaalenii_PYR-1 IRHYASVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLPD
Mflv_0413|M.gilvum_PYR-GCK IKHYASVGGDHNPIHTNGIAARLFGFPTVIAHGMFTAAAVLANVEGQLPD
MSMEG_0371|M.smegmatis_MC2_155 IRHYAAVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLSD
MMAR_0502|M.marinum_M IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
MUL_1165|M.ulcerans_Agy99 IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
Mb0247c|M.bovis_AF2122/97 IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
Rv0241c|M.tuberculosis_H37Rv IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
MLBr_02566|M.leprae_Br4923 IRRYAAVGGDHNPIHTNPIVAKLFGFPTTIAHGMFSAAAVLANIEARLPD
MAV_4917|M.avium_104 IRRYAVVGGDHNPIHTNPIAAKLFGFPTVIAHGMFSAAAVLANIEAAIPD
TH_1913|M.thermoresistible__bu IRRYASVGGDHNPIHTSSLGAKLFGFPTVIAHGMYTAAAVLANIEGRLPD
MAB_4444|M.abscessus_ATCC_1997 IRRYASVGGDHNPIHTSSIGAKALGFPKAIAHGMFTAAAVLGNIQGDIPD
*::** **********. : *: :***..*****::*****.*::. :.*
Mvan_0258|M.vanbaalenii_PYR-1 AVKYSVRFAKPVVLPARAGLYVDRSAD---AWELTLRHLTKGYPHLQATV
Mflv_0413|M.gilvum_PYR-GCK GVKYSVRFAKPVILPARAGLYVDRRAD---GWDLTLRHLTKGHPHLTGTL
MSMEG_0371|M.smegmatis_MC2_155 AVKHSVRFAKPVVLPAKAALYVERDAD---GWELTLRHLTKGYPHLTATV
MMAR_0502|M.marinum_M AVRYSVRFGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
MUL_1165|M.ulcerans_Agy99 AVRYSVRLGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
Mb0247c|M.bovis_AF2122/97 AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
Rv0241c|M.tuberculosis_H37Rv AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
MLBr_02566|M.leprae_Br4923 AVHYSARFVKPVVLPATTGLYVDESAG---NWDLTLRNIAKGYPHLAGTV
MAV_4917|M.avium_104 AVRYSVRFGKPVVLPATTGLYIDEHDG---GWDIALRNIAKGYPHLTGTV
TH_1913|M.thermoresistible__bu AVRYSVRFGKPLVLPAAAGLYVQQTDG---GWELALRHLTKGYPHLTAMV
MAB_4444|M.abscessus_ATCC_1997 AVRYDVKFGKPVLLPAAVGVWIDRPGGPGTAWDIAVRNPRNGDPHVTGSV
.*::..:: **::*** ..::: . *::::*: :* **: . :
Mvan_0258|M.vanbaalenii_PYR-1 TSLR
Mflv_0413|M.gilvum_PYR-GCK TSL-
MSMEG_0371|M.smegmatis_MC2_155 TPL-
MMAR_0502|M.marinum_M KPL-
MUL_1165|M.ulcerans_Agy99 KPL-
Mb0247c|M.bovis_AF2122/97 RGL-
Rv0241c|M.tuberculosis_H37Rv RGL-
MLBr_02566|M.leprae_Br4923 QGV-
MAV_4917|M.avium_104 RAL-
TH_1913|M.thermoresistible__bu TPL-
MAB_4444|M.abscessus_ATCC_1997 TPL-
: