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M. leprae Br4923 MLBr_02566 (-)

annotation: hypothetical protein MLBr_02566
coordinates: 3061237 - 3062139
length: 300

LTFGFVLRRLRRHFSVKENTVNQPSGLKNILRAIVGALPLLPRTDQLPSRTVTIEELPIDHTNVSAYASV
TGLRYGNHVPLTYPFALTFPAMMSLVTGFDFPFAAMGSVHTENHITQYRPIAVTDVVGVQVHAENLREHR
KGLLVDLVTDVSVGNDTAWHQVTTFLHLQRTSLSDEPKPPSQKQPKLLPPSAVLQITPRQIRRYAAVGGD
HNPIHTNPIVAKLFGFPTTIAHGMFSAAAVLANIEARLPDAVHYSARFVKPVVLPATTGLYVDESAGNWD
LTLRNIAKGYPHLAGTVQGV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02566--100% (300)hypothetical protein MLBr_02566
M. leprae Br4923MLBr_01909-3e-0733.33% (81) (3R)-hydroxyacyl-ACP dehydratase subunit HadB
M. leprae Br4923MLBr_01191fas9e-0741.18% (68) fatty acid synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0247c-1e-13682.14% (280) hypothetical protein Mb0247c
M. gilvum PYR-GCKMflv_0413-1e-12073.45% (275) dehydratase
M. tuberculosis H37RvRv0241c-1e-13682.14% (280) hypothetical protein Rv0241c
M. abscessus ATCC 19977MAB_4444-1e-9257.91% (278) hypothetical protein MAB_4444
M. marinum MMMAR_0502-1e-13178.65% (281) hypothetical protein MMAR_0502
M. avium 104MAV_4917-1e-13582.50% (280) MaoC like domain-containing protein
M. smegmatis MC2 155MSMEG_0371-1e-12374.82% (282) MaoC like domain-containing protein
M. thermoresistible (build 8)TH_1913-1e-11069.40% (268) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1165-1e-13078.29% (281) hypothetical protein MUL_1165
M. vanbaalenii PYR-1Mvan_0258-1e-12676.70% (279) dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0413|M.gilvum_PYR-GCK          ---------------MSD---KQPSGLKNLALAAAGALPFVPRGDTLPTR
Mvan_0258|M.vanbaalenii_PYR-1       ---------------MNES--KQPSGLKNLALAVAGALPLVPRGDTLPTR
MSMEG_0371|M.smegmatis_MC2_155      ---------------MADTQTTQPSGLKNMARAVVGALPFVTRSESLPKR
MLBr_02566|M.leprae_Br4923          MTFGFVLRRLRRHFSVKENTVNQPSGLKNILRAIVGALPLLPRTDQLPSR
MAV_4917|M.avium_104                -------------------MMNQPSGLKNMLCAAAGALPVVSRGSALPTR
MMAR_0502|M.marinum_M               --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
MUL_1165|M.ulcerans_Agy99           --------------------MNQPSGLKNMLRAAAGALPVVPRGDALPNR
Mb0247c|M.bovis_AF2122/97           --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
Rv0241c|M.tuberculosis_H37Rv        --------------------MTQPSGLKNLLRAAAGALPVVPRTDQLPNR
TH_1913|M.thermoresistible__bu      -----------------------------MVRAAAGALPVVRRDGTLPKR
MAB_4444|M.abscessus_ATCC_1997      --------------------MAQPSGLQNMVMAAVGALPFIPRPSTLPTR
                                                                 :  * .****.: *   **.*

Mflv_0413|M.gilvum_PYR-GCK          TLTVEDLSIDPVNVAEYADVTGLRFDNTVPLTYPFALTFPTVMQLITGFD
Mvan_0258|M.vanbaalenii_PYR-1       TLTVEDLTIDPVNVAEYANVTGLRFGNTVPLTYPFALTFPTVMALLTGFD
MSMEG_0371|M.smegmatis_MC2_155      TVTVDDLTIDPANVAEYAQVTGLRFGDAVPLTYPFTLTFPAVMSLVTGLD
MLBr_02566|M.leprae_Br4923          TVTIEELPIDHTNVSAYASVTGLRYGNHVPLTYPFALTFPAMMSLVTGFD
MAV_4917|M.avium_104                TVTVEDLPIDRTNVAEYAAVTGLRYRNHVPLTYPFALTFPALMSLVTGFD
MMAR_0502|M.marinum_M               TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
MUL_1165|M.ulcerans_Agy99           TVSVEELPIDHTNVAAYAAVTGLRYRNNVPLTYPFVLAFPSVMALVTGFD
Mb0247c|M.bovis_AF2122/97           TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
Rv0241c|M.tuberculosis_H37Rv        TVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFD
TH_1913|M.thermoresistible__bu      TVTATDLPIDAAHVADYAAVTGLLFRDQVPLTYPFALTFPHVMELLSGFD
MAB_4444|M.abscessus_ATCC_1997      VVRTQGVKIDPANVAAYAQVTGLTFSDKVPVTYPFTLQFPSVMSLVASLD
                                    .:    : ** .:*: ** **** : : **:****.* ** :* *::.:*

Mflv_0413|M.gilvum_PYR-GCK          FPFAAMGSVHLENHITQLRPIAVTDTVSVAVHAENMREHRRGLLVDILTD
Mvan_0258|M.vanbaalenii_PYR-1       FPFAAMGSVHLENHITQYRPIAVTDTVSVGVHAENMREHRRGLLVDVVTD
MSMEG_0371|M.smegmatis_MC2_155      FPFAAMGSVHIENHITQYRPIAVTDTVGVAVHAENLREHRRGLLVDIVTD
MLBr_02566|M.leprae_Br4923          FPFAAMGSVHTENHITQYRPIAVTDVVGVQVHAENLREHRKGLLVDLVTD
MAV_4917|M.avium_104                FPFAAMGSVHTENHITQYRPIAVTDTVGVRVHAENLREHRKGLLVDLVTD
MMAR_0502|M.marinum_M               FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
MUL_1165|M.ulcerans_Agy99           FPFAAMGSVHTENHITQYRPIAVTDTVGVKVHAENLREHRKGLMVDLVTD
Mb0247c|M.bovis_AF2122/97           FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
Rv0241c|M.tuberculosis_H37Rv        FPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTN
TH_1913|M.thermoresistible__bu      FPFPAIGAVHVENHITQQRPILVTDIVNISVHAENLREHRRGLLVDLVTD
MAB_4444|M.abscessus_ATCC_1997      FPFPAIGTVHLENHITQHRAISATDTVDIEVRAENLREHRKGLLVDVLTD
                                    ***.*:*::* ****** *.* .** *.: *:***:****:**:**::*:

Mflv_0413|M.gilvum_PYR-GCK          VRVGNELAWQQVTTFLHQQRTSLSDEPKPPPQKQPKLPPPNAVLRITPAQ
Mvan_0258|M.vanbaalenii_PYR-1       VKVGNDPAWHQITTFLHQQRTSLSDQPKPPPQKQPKLPPPNAVLRITPAQ
MSMEG_0371|M.smegmatis_MC2_155      VKVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPNAVLRITPGQ
MLBr_02566|M.leprae_Br4923          VSVGNDTAWHQVTTFLHLQRTSLSDEPKPPSQKQPKLLPPSAVLQITPRQ
MAV_4917|M.avium_104                VSVGNDTAWHQVTTFLHQQRTSLSDQPKPPPQKQPKLPPPPTVLRITPGL
MMAR_0502|M.marinum_M               INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
MUL_1165|M.ulcerans_Agy99           INVGNELAWHQVTTFLHQQRTSLSGEPKPPPQKQPKLPPPAAVLRITPAQ
Mb0247c|M.bovis_AF2122/97           VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
Rv0241c|M.tuberculosis_H37Rv        VSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAK
TH_1913|M.thermoresistible__bu      IYVGNEAAWHQVSTFLHQQRTSLSDEPKPPPAKQPKLGPPNAVLRVTPGQ
MAB_4444|M.abscessus_ATCC_1997      ITIGTDTVWQQTMTFLRQQRTSLSGGPKPEPPKAVKLPPPNSTLRISGGQ
                                    : :*.: .*:*  ***: ******. *** . *  ** ** :.*:::   

Mflv_0413|M.gilvum_PYR-GCK          IKHYASVGGDHNPIHTNGIAARLFGFPTVIAHGMFTAAAVLANVEGQLPD
Mvan_0258|M.vanbaalenii_PYR-1       IRHYASVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLPD
MSMEG_0371|M.smegmatis_MC2_155      IRHYAAVGGDHNPIHTNAIAAKLFGFPTVIAHGMFSAAAVLANIEGQLSD
MLBr_02566|M.leprae_Br4923          IRRYAAVGGDHNPIHTNPIVAKLFGFPTTIAHGMFSAAAVLANIEARLPD
MAV_4917|M.avium_104                IRRYAVVGGDHNPIHTNPIAAKLFGFPTVIAHGMFSAAAVLANIEAAIPD
MMAR_0502|M.marinum_M               IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
MUL_1165|M.ulcerans_Agy99           IRRYAAVGGDHNPIHTNSIAAKLFGFPTVIAHGMFSAAAVLANIEAKIPD
Mb0247c|M.bovis_AF2122/97           IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
Rv0241c|M.tuberculosis_H37Rv        IRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPD
TH_1913|M.thermoresistible__bu      IRRYASVGGDHNPIHTSSLGAKLFGFPTVIAHGMYTAAAVLANIEGRLPD
MAB_4444|M.abscessus_ATCC_1997      IRRYASVGGDHNPIHTSSIGAKALGFPKAIAHGMFTAAAVLGNIQGDIPD
                                    *::** **********. : *: :***..*****::*****.*::. :.*

Mflv_0413|M.gilvum_PYR-GCK          GVKYSVRFAKPVILPARAGLYVDRRAD---GWDLTLRHLTKGHPHLTGTL
Mvan_0258|M.vanbaalenii_PYR-1       AVKYSVRFAKPVVLPARAGLYVDRSAD---AWELTLRHLTKGYPHLQATV
MSMEG_0371|M.smegmatis_MC2_155      AVKHSVRFAKPVVLPAKAALYVERDAD---GWELTLRHLTKGYPHLTATV
MLBr_02566|M.leprae_Br4923          AVHYSARFVKPVVLPATTGLYVDESAG---NWDLTLRNIAKGYPHLAGTV
MAV_4917|M.avium_104                AVRYSVRFGKPVVLPATTGLYIDEHDG---GWDIALRNIAKGYPHLTGTV
MMAR_0502|M.marinum_M               AVRYSVRFGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
MUL_1165|M.ulcerans_Agy99           AVRYSVRLGKPVLLPATAGLYIDEADAADPGWEIALRNMSKGYPHLTATI
Mb0247c|M.bovis_AF2122/97           AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
Rv0241c|M.tuberculosis_H37Rv        AVRYSVRFAKPVLLPATAGLYVAEGDG---GWDLTLRNMAKGYPHLTATV
TH_1913|M.thermoresistible__bu      AVRYSVRFGKPLVLPAAAGLYVQQTDG---GWELALRHLTKGYPHLTAMV
MAB_4444|M.abscessus_ATCC_1997      AVRYDVKFGKPVLLPAAVGVWIDRPGGPGTAWDIAVRNPRNGDPHVTGSV
                                    .*::..:: **::*** ..::: .       *::::*:  :* **: . :

Mflv_0413|M.gilvum_PYR-GCK          TSL-
Mvan_0258|M.vanbaalenii_PYR-1       TSLR
MSMEG_0371|M.smegmatis_MC2_155      TPL-
MLBr_02566|M.leprae_Br4923          QGV-
MAV_4917|M.avium_104                RAL-
MMAR_0502|M.marinum_M               KPL-
MUL_1165|M.ulcerans_Agy99           KPL-
Mb0247c|M.bovis_AF2122/97           RGL-
Rv0241c|M.tuberculosis_H37Rv        RGL-
TH_1913|M.thermoresistible__bu      TPL-
MAB_4444|M.abscessus_ATCC_1997      TPL-
                                      :