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M. tuberculosis H37Rv Rv2524c (fas)

annotation: PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE)
coordinates: 2840123 - 2849332
length: 3069

TIHEHDRVSADRGGDSPHTTHALVDRLMAGEPYAVAFGGQGSAWLETLEELVSATGIETELATLVGEAEL
LLDPVTDELIVVRPIGFEPLQWVRALAAEDPVPSDKHLTSAAVSVPGVLLTQIAATRALARQGMDLVATP
PVAMAGHSQGVLAVEALKAGGARDVELFALAQLIGAAGTLVARRRGISVLGDRPPMVSVTNADPERIGRL
LDEFAQDVRTVLPPVLSIRNGRRAVVITGTPEQLSRFELYCRQISEKEEADRKNKVRGGDVFSPVFEPVQ
VEVGFHTPRLSDGIDIVAGWAEKAGLDVALARELADAILIRKVDWVDEITRVHAAGARWILDLGPGDILT
RLTAPVIRGLGIGIVPAATRGGQRNLFTVGATPEVARAWSSYAPTVVRLPDGRVKLSTKFTRLTGRSPIL
LAGMTPTTVDAKIVAAAANAGHWAELAGGGQVTEEIFGNRIEQMAGLLEPGRTYQFNALFLDPYLWKLQV
GGKRLVQKARQSGAAIDGVVISAGIPDLDEAVELIDELGDIGISHVVFKPGTIEQIRSVIRIATEVPTKP
VIMHVEGGRAGGHHSWEDLDDLLLATYSELRSRANITVCVGGGIGTPRRAAEYLSGRWAQAYGFPLMPID
GILVGTAAMATKESTTSPSVKRMLVDTQGTDQWISAGKAQGGMASSRSQLGADIHEIDNSASRCGRLLDE
VAGDAEAVAERRDEIIAAMAKTAKPYFGDVADMTYLQWLRRYVELAIGEGNSTADTASVGSPWLADTWRD
RFEQMLQRAEARLHPQDFGPIQTLFTDAGLLDNPQQAIAALLARYPDAETVQLHPADVPFFVTLCKTLGK
PVNFVPVIDQDVRRWWRSDSLWQAHDARYDADAVCIIPGTASVAGITRMDEPVGELLDRFEQAAIDEVLG
AGVEPKDVASRRLGRADVAGPLAVVLDAPDVRWAGRTVTNPVHRIADPAEWQVHDGPENPRATHSSTGAR
LQTHGDDVALSVPVSGTWVDIRFTLPANTVDGGTPVIATEDATSAMRTVLAIAAGVDSPEFLPAVANGTA
TLTVDWHPERVADHTGVTATFGEPLAPSLTNVPDALVGPCWPAVFAAIGSAVTDTGEPVVEGLLSLVHLD
HAARVVGQLPTVPAQLTVTATAANATDTDMGRVVPVSVVVTGADGAVIATLEERFAILGRTGSAELADPA
RAGGAVSANATDTPRRRRRDVTITAPVDMRPFAVVSGDHNPIHTDRAAALLAGLESPIVHGMWLSAAAQH
AVTATDGQARPPARLVGWTARFLGMVRPGDEVDFRVERVGIDQGAEIVDVAARVGSDLVMSASARLAAPK
TVYAFPGQGIQHKGMGMEVRARSKAARKVWDTADKFTRDTLGFSVLHVVRDNPTSIIASGVHYHHPDGVL
YLTQFTQVAMATVAAAQVAEMREQGAFVEGAIACGHSVGEYTALACVTGIYQLEALLEMVFHRGSKMHDI
VPRDELGRSNYRLAAIRPSQIDLDDADVPAFVAGIAESTGEFLEIVNFNLRGSQYAIAGTVRGLEALEAE
VERRRELTGGRRSFILVPGIDVPFHSRVLRVGVAEFRRSLDRVMPRDADPDLIIGRYIPNLVPRLFTLDR
DFIQEIRDLVPAEPLDEILADYDTWLRERPREMARTVFIELLAWQFASPVRWIETQDLLFIEEAAGGLGV
ERFVEIGVKSSPTVAGLATNTLKLPEYAHSTVEVLNAERDAAVLFATDTDPEPEPEEDEPVAESPAPDVV
SEAAPVAPAASSAGPRPDDLVFDAADATLALIALSAKMRIDQIEELDSIESITDGASSRRNQLLVDLGSE
LNLGAIDGAAESDLAGLRSQVTKLARTYKPYGPVLSDAINDQLRTVLGPSGKRPGAIAERVKKTWELGEG
WAKHVTVEVALGTREGSSVRGGAMGHLHEGALADAASVDKVIDAAVASVAARQGVSVALPSAGSGGGATI
DAAALSEFTDQITGREGVLASAARLVLGQLGLDDPVNALPAAPDSELIDLVTAELGADWPRLVAPVFDPK
KAVVFDDRWASAREDLVKLWLTDEGDIDADWPRLAERFEGAGHVVATQATWWQGKSLAAGRQIHASLYGR
IAAGAENPEPGRYGGEVAVVTGASKGSIAASVVARLLDGGATVIATTSKLDEERLAFYRTLYRDHARYGA
ALWLVAANMASYSDVDALVEWIGTEQTESLGPQSIHIKDAQTPTLLFPFAAPRVVGDLSEAGSRAEMEMK
VLLWAVQRLIGGLSTIGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSWAARVS
LAHALIGWTRGTGLMGHNDAIVAAVEEAGVTTYSTDEMAALLLDLCDAESKVAAARSPIKADLTGGLAEA
NLDMAELAAKAREQMSAAAAVDEDAEAPGAIAALPSPPRGFTPAPPPQWDDLDVDPADLVVIVGGAEIGP
YGSSRTRFEMEVENELSAAGVLELAWTTGLIRWEDDPQPGWYDTESGEMVDESELVQRYHDAVVQRVGIR
EFVDDGAIDPDHASPLLVSVFLEKDFAFVVSSEADARAFVEFDPEHTVIRPVPDSTDWQVIRKAGTEIRV
PRKTKLSRVVGGQIPTGFDPTVWGISADMAGSIDRLAVWNMVATVDAFLSSGFSPAEVMRYVHPSLVANT
QGTGMGGGTSMQTMYHGNLLGRNKPNDIFQEVLPNIIAAHVVQSYVGSYGAMIHPVAACATAAVSVEEGV
DKIRLGKAQLVVAGGLDDLTLEGIIGFGDMAATADTSMMCGRGIHDSKFSRPNDRRRLGFVEAQGGGTIL
LARGDLALRMGLPVLAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGKDSPLARALAKLGVAADDVAVISK
HDTSTLANDPNETELHERLADALGRSEGAPLFVVSQKSLTGHAKGGAAVFQMMGLCQILRDGVIPPNRSL
DCVDDELAGSAHFVWVRDTLRLGGKFPLKAGMLTSLGFGHVSGLVALVHPQAFIASLDPAQRADYQRRAD
ARLLAGQRRLASAIAGGAPMYQRPGDRRFDHHAPERPQEASMLLNPAARLGDGEAYIG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2524cfas-100% (3069)PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE)
M. tuberculosis H37RvRv2245kasA1e-1928.00% (300) 3-oxoacyl-(acyl carrier protein) synthase II
M. tuberculosis H37RvRv2246kasB3e-1829.07% (289) 3-oxoacyl-(acyl carrier protein) synthase II

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2553cfas0.099.97% (3069) fatty acid synthase
M. gilvum PYR-GCKMflv_2532-0.078.67% (3085) dehydratase
M. leprae Br4923MLBr_01191fas0.085.84% (3080) fatty acid synthase
M. abscessus ATCC 19977MAB_1512-0.077.40% (3093) fatty acid synthase Fas
M. marinum MMMAR_3962fas0.090.46% (3072) fatty acid synthase Fas
M. avium 104MAV_1650-0.088.67% (3089) fatty acid synthase
M. smegmatis MC2 155MSMEG_4757-0.081.80% (3088) fatty acid synthase
M. thermoresistible (build 8)TH_1319fas0.082.08% (1289) PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE)
M. ulcerans Agy99MUL_3818fas0.090.30% (3072) fatty acid synthase Fas
M. vanbaalenii PYR-1Mvan_4125-0.078.46% (3096) dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2532|M.gilvum_PYR-GCK          --MTINDQHRATT----DSNGRPDKDFEPLTGTHALVDRFHSGEPYAVAF
Mvan_4125|M.vanbaalenii_PYR-1       --MTINDQHRATT----DSDGQVAQGFEPLTGTHALVDRLHSGEPYAVAF
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      --MTIYEHDRVPAGWNDESGSDRTADGNAADTAHALVDRLSAGEPYAVAF
Rv2524c|M.tuberculosis_H37Rv        --MTIHEHDRVSADR--GGDSPH--------TTHALVDRLMAGEPYAVAF
Mb2553c|M.bovis_AF2122/97           --MTIHEHDRVSADR--GGDSPH--------TTHALVDRLMAGEPYAVAF
MMAR_3962|M.marinum_M               --MTIHEHDRVSADR--DETGPH--------STHALVDRLTTGEPFAVAF
MUL_3818|M.ulcerans_Agy99           MNVTIHEHDRVSADR--DETGPH--------STHALVDRLTAGEPFAVAF
MLBr_01191|M.leprae_Br4923          --MTIHEHDQVSADR--NGNSLH--------GSRALADRLKAGEPYVVAF
MAV_1650|M.avium_104                --MTIHEHDRVSADR--DGQGPHGVKHPPAGDTHALVDRLAAGEPYAVAF
MAB_1512|M.abscessus_ATCC_1997      --MTINEYDKVTSSEDPDANGAVDPG---PSAGPALIDRLESGEPYAVAF
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          GGQGGPWLENLEELVNSAGIESEISQLVAEAELLLEPLARELVVVRPIGF
Mvan_4125|M.vanbaalenii_PYR-1       GGQGGPWLENLEELVNSAGIESEISQLVAEAELMLEPLARELVVVRPIGF
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      GGQGSAWLETLEELVSSAGIESELATLAGEAELLLEPVASELVVVRPIGF
Rv2524c|M.tuberculosis_H37Rv        GGQGSAWLETLEELVSATGIETELATLVGEAELLLDPVTDELIVVRPIGF
Mb2553c|M.bovis_AF2122/97           GGQGSAWLETLEELVSATGIETELATLVGEAELLLDPVTDELIVVRPIGF
MMAR_3962|M.marinum_M               GGQGSAWLETLEELVSAAGIESELAALVGEVELLLEPVSKELVVVRPIGF
MUL_3818|M.ulcerans_Agy99           GGQGSAWLETLEELVSAPGIESELAALVGEVELLLEPVSKELVVVRPIGF
MLBr_01191|M.leprae_Br4923          GGQGSAWLETLEELVSSAGLEADLATLVCEVELLLEPVAKELVVVRPIGF
MAV_1650|M.avium_104                GGQGSAWLETLEELVSSAGIEPELATLVGEVDLLLEPVAKELVVVRPIGF
MAB_1512|M.abscessus_ATCC_1997      GGQGSDWLESLADLAASAGIESELATLAGEAELRLEPVAKELVVVRPVGF
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          EPMRWIRALAAEEPLPSTKDLTTAAISGPGILLTQMAAQRALKRQGLDLD
Mvan_4125|M.vanbaalenii_PYR-1       EPMKWIRALAADEPLPAAKDLTTAAISGPGILLTQMAAQRALKRQGLDLD
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      EPLQWVRALAAEEPVPSDKQLTSAAVSVPGVLLTQIAAVRALARQGMDLT
Rv2524c|M.tuberculosis_H37Rv        EPLQWVRALAAEDPVPSDKHLTSAAVSVPGVLLTQIAATRALARQGMDLV
Mb2553c|M.bovis_AF2122/97           EPLQWVRALAAEDPVPSDKHLTSAAVSVPGVLLTQIAATRALARQGMDLV
MMAR_3962|M.marinum_M               EPLQWVRALAAEDPVPSDKHLTSSAVSLPGVLLTQVAAVRALARQGMDLI
MUL_3818|M.ulcerans_Agy99           EPLQWVRALAAEDPVPSDKHLTSSAVSLPGVLLTQVAAVRALARQGMDLI
MLBr_01191|M.leprae_Br4923          EPLQWVRALLAEDLVPSDKHLTSAAVSVPGVLLTQIAVGRALARQGMDLI
MAV_1650|M.avium_104                EPLSWVRALAAEDPVPSNKHLTSAAVSIPGVLLTQIAAVRALARQGMDLT
MAB_1512|M.abscessus_ATCC_1997      SPLTWVRALTAEEPVPAAAQLTSAAVSMPGVLLAQLAAVRALKIQGLDLA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          AHPPVAVAGHSQGVTAVESLKAGGARDVELLAIGQLIGAAGSLVSRRCGM
Mvan_4125|M.vanbaalenii_PYR-1       GHPPVAIAGHSQGVTAVESLKAGGTRDVELLAIGQLIGAAGSLVSRRCGM
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      ATPPVAVAGHSQGVLAVQALAAKGAKDVELLALAQLIGAAGTLVARRRGI
Rv2524c|M.tuberculosis_H37Rv        ATPPVAMAGHSQGVLAVEALKAGGARDVELFALAQLIGAAGTLVARRRGI
Mb2553c|M.bovis_AF2122/97           ATPPVAMAGHSQGVLAVEALKAGGARDVELFALAQLIGAAGTLVARRRGI
MMAR_3962|M.marinum_M               ATPPVVSVGHSQGVLAVEALNAGGARDVELLALAQLIGAAGTLVARRRGI
MUL_3818|M.ulcerans_Agy99           ATPPVVSVGHSQGVLAVEALNAGGARDVELLALAQLIGAAGTLVARRRGI
MLBr_01191|M.leprae_Br4923          ATPPVGIVGHSQGVLAVEALKAGGARDAELLAMAQLIGAAGTLVARRRGI
MAV_1650|M.avium_104                ATPPVAVAGHSQGVLAVEALKGAGARDVELLALAQLIGAAGTLVARRRGI
MAB_1512|M.abscessus_ATCC_1997      QLPPVAVIGHSQGVLAVEALKAHGARDVELLAIAQLVGAAATLVARRRGI
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          VSRGDKAPMVSVLNVDPARIAELLEEFAQDVRTVLPPALSIRNGRRSVVI
Mvan_4125|M.vanbaalenii_PYR-1       VGRGDKSPMVSVLNVDPARIAELLHDFAQDVRTVLPPALSIRNGRRSVVI
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      TVLGDRPPMVSVTNADPERIYELLEEFSSDVRTVLPPVLSIRNGRRSVVI
Rv2524c|M.tuberculosis_H37Rv        SVLGDRPPMVSVTNADPERIGRLLDEFAQDVRTVLPPVLSIRNGRRAVVI
Mb2553c|M.bovis_AF2122/97           SVLGDRPPMVSVTNADPERIGRLLDEFAQDVRTVLPPVLSIRNGRRAVVI
MMAR_3962|M.marinum_M               SVLGDRPPMVSVTNADPERIQQLLEDFAQDVRTVLPPVLSIRNGRRSVVI
MUL_3818|M.ulcerans_Agy99           SVLGDRPPMVSVTNADPERIQQLLEDFAQDVRTVLPPVLSIRSGRRSVVI
MLBr_01191|M.leprae_Br4923          SVLGDRPPMVSVTNADPERIRRLLDEFAQDVRTVLPPVLSIRNGWRSVVI
MAV_1650|M.avium_104                SVLGDRPPMVSVTNADPERISRLLDEFAQDVRTVLPPVLSIRNGRRSVVI
MAB_1512|M.abscessus_ATCC_1997      VVRGNRTPMVSVTNVDPERMKALLDEFAQDVRTVQPPALSIRNGRRSVVI
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          TGTPEQLARFELYCEKITEKEEAERKNKTRGGAIFRPVFNQLSVEVGFHT
Mvan_4125|M.vanbaalenii_PYR-1       TGTPEQLARFELYCEKITEKEEAERKNKVRGGAIFRPVFNQLNVEVGFHT
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      TGTPEQLSRFELYCTQIAEKEEAERKNKLRGGAVFAPVFDPVQVEVGFHT
Rv2524c|M.tuberculosis_H37Rv        TGTPEQLSRFELYCRQISEKEEADRKNKVRGGDVFSPVFEPVQVEVGFHT
Mb2553c|M.bovis_AF2122/97           TGTPEQLSRFELYCRQISEKEEADRKNKVRGGDVFSPVFEPVQVEVGFHT
MMAR_3962|M.marinum_M               TGTPEQLSRFELYCRQISEKEEAERKSKVRGGDVFAPVFDPVKVEVGFHT
MUL_3818|M.ulcerans_Agy99           TGTPEQLSRFELYCRQISEKEEAERKSKVRGGDVFAPVFDPVKVEVGFHT
MLBr_01191|M.leprae_Br4923          TGTPEQLSRFERYCRQISDKEEEDRRKKIRGGDIFAPVFDPVQVEIGFHT
MAV_1650|M.avium_104                TGTPEQLSRFELYCRQISEKEEAERKNKLRGGDVFAPVFDPVQVEVGFHT
MAB_1512|M.abscessus_ATCC_1997      TGTPEQLSRFELYCEQIAEREAAERKDKVRGGAIFSPVFDPVDVEVGFHT
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          PRLAGGVDLVNEWASRTGLDRELTRTLAETIFVNPVDWVAEVEGLAATGA
Mvan_4125|M.vanbaalenii_PYR-1       PRLAGGVELVNEWASRTGLDRELTRKLTEAIFIDPVDWVSEVEGLAEAGA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      PRLSDGIEIVGRWAETVGLDVELAKELTESILVRQVDWVDEITELHEAGA
Rv2524c|M.tuberculosis_H37Rv        PRLSDGIDIVAGWAEKAGLDVALARELADAILIRKVDWVDEITRVHAAGA
Mb2553c|M.bovis_AF2122/97           PRLSDGIDIVAGWAEKAGLDVALARELADAILIRKVDWVDEITRVHAAGA
MMAR_3962|M.marinum_M               PRLADGIDIVGGWAEKVGLDVALARQLAEAILVDTVDWVSDINRVHEAGA
MUL_3818|M.ulcerans_Agy99           PRLADGIDIVGGWAEKVGLDVALARQLAEAILVDTVDWVSDINRVHEAGA
MLBr_01191|M.leprae_Br4923          PHLADGIGIVGGWAEKVGLDVTLARELTEAILVRGVDWVREITRVHGAGV
MAV_1650|M.avium_104                PRLADGIDIVGGWAEKVGLDVALARELTEAILVRRVDWVQEITRVHESGA
MAB_1512|M.abscessus_ATCC_1997      PRLADGVEIAGRWAAAAGLDVELTKSLTEAILVTPVDWVNEVNHVADAGA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          KWIVDLGPSDTVTRLTAPVIRGLGIGIVPAATRAGQRSLFTVGAAPAVAP
Mvan_4125|M.vanbaalenii_PYR-1       KWIVDLGPSDTVTRLTAPVIRGLGIGIVAAATRAGQRSLFTVGAAPAVAP
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      RWILDLGPGDILTRLTAPVIRGLGIGIVPAATRGGQRNLFTVGAVPEVAR
Rv2524c|M.tuberculosis_H37Rv        RWILDLGPGDILTRLTAPVIRGLGIGIVPAATRGGQRNLFTVGATPEVAR
Mb2553c|M.bovis_AF2122/97           RWILDLGPGDILTRLTAPVIRGLGIGIVPAATRGGQRNLFTVGATPEVAR
MMAR_3962|M.marinum_M               RWILDLGPGDILTRLTASVIRGLGIGIVPAATRGGQRNLFTVGATPEVAR
MUL_3818|M.ulcerans_Agy99           RWILDLGPGDILTRLTAPVIRGSGIGIVPAATRGGQRNLFTVGATPEVAR
MLBr_01191|M.leprae_Br4923          RWIIDLGPGDILTRLTAPVIRGLGVGIVPVANRGGQRTLFTVGAVPEVVR
MAV_1650|M.avium_104                RWILDLGPGDILTRLTAPVIRGLGVGIVPAATRGGQRNLFTVGAVPEVAR
MAB_1512|M.abscessus_ATCC_1997      RWILDLGPGDLLTRLTAPVIRGLGIGIVPTATRGGQRNLFMHGAVPEVAR
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          AWASYAPKPVALPDGSVKASTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
Mvan_4125|M.vanbaalenii_PYR-1       AWSSYAPQPIALPDGSVKASTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      PWSSYAPTVVKLPDGSVKLETKFTRLTGRSPILLAGMTPTTVDAKIVAAA
Rv2524c|M.tuberculosis_H37Rv        AWSSYAPTVVRLPDGRVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
Mb2553c|M.bovis_AF2122/97           AWSSYAPTVVRLPDGRVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
MMAR_3962|M.marinum_M               AWSSYAPTAVRLPDGRVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
MUL_3818|M.ulcerans_Agy99           AWSSYAPTAVRLPDGRVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
MLBr_01191|M.leprae_Br4923          AWLSYAPTVVQLPDGRIKLSTKFTRLTGRSPILLAGMTPTTVDANIVAAA
MAV_1650|M.avium_104                AWSSYAPTLVRLPDGRVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
MAB_1512|M.abscessus_ATCC_1997      AWTSFAPTVVSLPDGSVKLSTKFTRLTGRSPILLAGMTPTTVDAKIVAAA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          ANAGHWAELAGGGQVTEEIFDARIEELTELLEPGRAIQFNSLFLDPYLWK
Mvan_4125|M.vanbaalenii_PYR-1       ANAGHWAELAGGGQVTEEIFDARIKELTQLLEPGRAIQFNSLFLDPYLWK
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      ANAGHWAELAGGGQVTEQIFNDRIAELETLLEPGRAIQFNTLFLDPYLWK
Rv2524c|M.tuberculosis_H37Rv        ANAGHWAELAGGGQVTEEIFGNRIEQMAGLLEPGRTYQFNALFLDPYLWK
Mb2553c|M.bovis_AF2122/97           ANAGHWAELAGGGQVTEEIFGNRIEQMAGLLEPGRTYQFNALFLDPYLWK
MMAR_3962|M.marinum_M               ANAGHWAELAGGGQVTEEIFADRINEMSGLLEPGRTYQFNALFLDPYLWK
MUL_3818|M.ulcerans_Agy99           ANAGHWAELAGGGQVTEEIFADRINEMSGLLEPGRTYQFNALFLDPYLWK
MLBr_01191|M.leprae_Br4923          ANAGHWAELAGGGQVTEEIFANRVEQLSGLLEPGRTYQFNALFLDPYLWK
MAV_1650|M.avium_104                ANAGHWAELAGGGQVTEEIFAARIEELSGLLEEGRTYQFNALFLDPYLWK
MAB_1512|M.abscessus_ATCC_1997      ANAGHWSELAGGGQVTEEIFSKRIEELTGLLEPGRQIQFNSLFLDPYLWK
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          LQIGGKRLVQKARQSGAPIDGVVVTAGIPDLEEAVELIEELHTVGISNIV
Mvan_4125|M.vanbaalenii_PYR-1       LQVGGKRLVQKARQSGAPIDGVVVTAGIPDLEEAVELIEELHTVGISNVV
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      LQVGGKRLVQRARQSGAPIDGLVVSAGIPDLEEAVDIIDELNEVGISHVV
Rv2524c|M.tuberculosis_H37Rv        LQVGGKRLVQKARQSGAAIDGVVISAGIPDLDEAVELIDELGDIGISHVV
Mb2553c|M.bovis_AF2122/97           LQVGGKRLVQKARQSGAAIDGVVISAGIPDLDEAVELIDELGDIGISHVV
MMAR_3962|M.marinum_M               LQLGGKRLVQKARQSGAAIDGVVISAGIPDLEEAVELIDELNDIGISHVV
MUL_3818|M.ulcerans_Agy99           LQLGGKRLVQKARQSGAAIDGVVISAGIPDLEEAVELIDELNDIGISHVV
MLBr_01191|M.leprae_Br4923          LQVGGKRLVQKARQSGAAIDGVVISGGILDLEDAVELIEELGGIGISYVV
MAV_1650|M.avium_104                LQVGGKRLVQKARQSGAAIDGLVISAGIPELEEAVELIEELGDVGISNIV
MAB_1512|M.abscessus_ATCC_1997      LQVGSKRLVQKARQAGAPIDGVVVTAGIPELEEAVALIDELTEIGFSHIV
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          FKPGTVDQIKSVIKIAVEVPDRDVIVHVEGGRAGGHHSWEDLDDLLISTY
Mvan_4125|M.vanbaalenii_PYR-1       FKPGTVDQIKSVIKIAAEVPGRDVIVHIEGGRAGGHHSWEDLDDLLLTTY
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      FKPGTVEQIRSVIRIAAEVPTKPVIVHIEGGRAGGHHSWEDLDDLLLATY
Rv2524c|M.tuberculosis_H37Rv        FKPGTIEQIRSVIRIATEVPTKPVIMHVEGGRAGGHHSWEDLDDLLLATY
Mb2553c|M.bovis_AF2122/97           FKPGTIEQIRSVIRIATEVPTKPVIMHVEGGRAGGHHSWEDLDDLLLATY
MMAR_3962|M.marinum_M               FKPGTIEQIRSVIRIATEVPTKPVIMHVEGGRAGGHHSWEDLDDLLLATY
MUL_3818|M.ulcerans_Agy99           FKPGTIEQIRSVIRIATEVPTKPVIMHVEGGRAGGHHSWEDLDDLLLATY
MLBr_01191|M.leprae_Br4923          FKPGTIEQIRSVIRIATEMSTKPVIMHVEGGRAGGHHSWEDLDDLLLATY
MAV_1650|M.avium_104                FKPGTVEQIRSVIRIATEVSTKPVIVHIEGGRAGGHHSWEDLDDLLLATY
MAB_1512|M.abscessus_ATCC_1997      FKPGTVEQIRSVVRIAAEVPTRPIIMHVEGGRAGGHHSWEDLDDLLLTTY
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          GELRKYSNITICVGGGIGTPERAADYLSGEWAQAYGFPAMPVDGILVGTA
Mvan_4125|M.vanbaalenii_PYR-1       GELRKYSNVTICVGGGIGTPERAAEYLSGEWAKAYGFPDMPVDGILVGTA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      SELRSRSNITICVGGGIGTPERSAEYLSGRWAEVHGYPLMPIDGILVGTA
Rv2524c|M.tuberculosis_H37Rv        SELRSRANITVCVGGGIGTPRRAAEYLSGRWAQAYGFPLMPIDGILVGTA
Mb2553c|M.bovis_AF2122/97           SELRSRANITVCVGGGIGTPRRAAEYLSGRWAQAYGFPLMPIDGILVGTA
MMAR_3962|M.marinum_M               SELRSRANITVCVGGGIGTPERAAEYLSGRWAQAYGFPLMPIDGILVGTA
MUL_3818|M.ulcerans_Agy99           SELRSRANITVCVGGGIGTPERAAEYLSGRWAQAYGFPLMPIDGILVGTA
MLBr_01191|M.leprae_Br4923          SELRSHANITVCVGGGIGTPEKAAEYLSGRWAQAYGFPLMPIDGILVGTA
MAV_1650|M.avium_104                SELRSRPNITVCVGGGIGTPERAAEYLSGRWAEKYGFPLMPIDGILVGTA
MAB_1512|M.abscessus_ATCC_1997      SELRSRSNITVCVGGGIGTPEQAAEYLSGRWALKFGFPLMPVDGILVGTA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          AMATLEATTSPAVKQMLVETTGTDTWVGAGKAINGMASGRSQLGADIHEI
Mvan_4125|M.vanbaalenii_PYR-1       AMATLEATTSPAVKQLLVETTGTETWVGAGNAINGMASGRSQLGADIHEI
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      AMATLEATTSPQVKQLLVETKGTEAWVGAGKAANGMASGRSQLGADIHEI
Rv2524c|M.tuberculosis_H37Rv        AMATKESTTSPSVKRMLVDTQGTDQWISAGKAQGGMASSRSQLGADIHEI
Mb2553c|M.bovis_AF2122/97           AMATKESTTSPSVKRMLVDTQGTDQWISAGKAQGGMASSRSQLGADIHEI
MMAR_3962|M.marinum_M               AMAALEATTSPSVKKMLVETQGTGEWIGAGKAQGGMASSRSQLGADIHEI
MUL_3818|M.ulcerans_Agy99           AMAALEATTSPSVKKMLVETQGTGEWIGAGKAQGGMASSRSQLGADIHEI
MLBr_01191|M.leprae_Br4923          AMATKEATTSPSVKRMLVETQGTDQWIGSGKAQGGMASSRSQLGADIHEI
MAV_1650|M.avium_104                AMATLESTTSPSVKRMLVETQGTEHWIGAGKAVGGMASSRSQLGADIHEI
MAB_1512|M.abscessus_ATCC_1997      AMATLEATTSPSVKQMLVQTQGTPEWVPAGKAQGGMASGRSQLGADIHEI
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          DNTASRCGRLLDEVAGDADAVAERRDEIIAAMADTAKPYFGDVADMTYLQ
Mvan_4125|M.vanbaalenii_PYR-1       DNTASRCGRLLDEVAGDADAVAERRDELIAAMANTAKPYFGDVGDMTYLQ
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      DNAASRCGRLLDEVAGDADAVAERRDEIIAAMAQTAKPYFGDVAEMTYLQ
Rv2524c|M.tuberculosis_H37Rv        DNSASRCGRLLDEVAGDAEAVAERRDEIIAAMAKTAKPYFGDVADMTYLQ
Mb2553c|M.bovis_AF2122/97           DNSASRCGRLLDEVAGDAEAVAERRDEIIAAMAKTAKPYFGDVADMTYLQ
MMAR_3962|M.marinum_M               DNSASRCGQLLDEVAGDADAVAERRDEIIAAMAKTAKPYFGDIADMTYLQ
MUL_3818|M.ulcerans_Agy99           DNSASRCGQLLDEVAGDADAVAERRDEIITAMAKTAKPYFGDIADMTYLQ
MLBr_01191|M.leprae_Br4923          DNAASRCGRLLDEVAGDAEAVAERRDEIIAAMANTAKPYFGDVSEMTYLQ
MAV_1650|M.avium_104                DNSASRCGRLLDEVAGDAEAVAERRDEIIAAMAKTAKPYFGDVGEMTYLQ
MAB_1512|M.abscessus_ATCC_1997      DNAASRCGRLLDDVAGDADAVAKRRDEIIAAMELTAKQYFGDVAEMSYAQ
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          WLQRYVELAIGDGDSTADTAAPGSPWLADTWRDRFEEMLTRAEARLNEKD
Mvan_4125|M.vanbaalenii_PYR-1       WLQRYIELAIGDGDSTADTAAPGSPWLADTWRERFEEMLKRAEARLNEKD
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      WLRRYVELAIGDGNSTADTKRPDSPWLDITWRDRFEQMLKRAEARLHPQD
Rv2524c|M.tuberculosis_H37Rv        WLRRYVELAIGEGNSTADTASVGSPWLADTWRDRFEQMLQRAEARLHPQD
Mb2553c|M.bovis_AF2122/97           WLRRYVELAIGEGNSTADTASVGSPWLADTWRDRFEQMLQRAEARLHPQD
MMAR_3962|M.marinum_M               WLQRYVELAIGEGNSTADTAAPGSPWLADTWRDRFQQMLQRAEARLHPQD
MUL_3818|M.ulcerans_Agy99           WLQRYVELAIGEGNSTADTAAPGSPWLADTWRDRFQQMLQRAEARLHPQD
MLBr_01191|M.leprae_Br4923          WLQRYVELTIGEGNSTADTASPGSPWLADTWRDRFQKMLQRAESRLHPSD
MAV_1650|M.avium_104                WLQRYVELAIGDGDSTADTASPGSPWLADTWRDRFEQMLQRAEARLHAKD
MAB_1512|M.abscessus_ATCC_1997      WLNRYVELSIGDGDSTADTAVAHSPWLDITWRDRFEQMLKRAEARLHPKD
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          SGPIESLLAAD-----GKALLETPDVAIDALLTRYPDAETVKLHPADVPF
Mvan_4125|M.vanbaalenii_PYR-1       SGPIESLFSDSGASSGGQALLDNPDAAIAALLARYPDAESVKLHPADVPF
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      FGPIETLFDADAD---GERLLEDPEAAITALLQRYPDAETVVLHPADVPF
Rv2524c|M.tuberculosis_H37Rv        FGPIQTLFT-------DAGLLDNPQQAIAALLARYPDAETVQLHPADVPF
Mb2553c|M.bovis_AF2122/97           FGPIQTLFT-------DAGLLDNPQQAIAALLARYPDAETVQLHPADVPF
MMAR_3962|M.marinum_M               FGPIETAFA-------DPALLENPTQTIAALLARYPDAETVQLHPADVPF
MUL_3818|M.ulcerans_Agy99           FGPIETAFA-------DPALLENPTQTIAALLARYPDAETVQLHPADVPF
MLBr_01191|M.leprae_Br4923          FGLIKTIFT-------DPVLLEKPNQAIAALLKYYPDAETVQLHPADAPF
MAV_1650|M.avium_104                FGPIETLFDGSTED--GARLLENPAEAIATLLAHYPDAESVQLHPADVPF
MAB_1512|M.abscessus_ATCC_1997      FGPVETLFA-------DDTLLERPAEAIAALLQRYPDAESVKLHPADVPF
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          FVTLCKKPGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYTADQVCIIPGT
Mvan_4125|M.vanbaalenii_PYR-1       FVTLCKKPGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYSADQVCIIPGT
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      FVELCKTLGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYEADQVCVIPGT
Rv2524c|M.tuberculosis_H37Rv        FVTLCKTLGKPVNFVPVIDQDVRRWWRSDSLWQAHDARYDADAVCIIPGT
Mb2553c|M.bovis_AF2122/97           FVTLCKTLGKPVNFVPVIDQDVRRWWRSDSLWQAHDARYDADAVCIIPGT
MMAR_3962|M.marinum_M               FVTLCKTLGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYDADQVCIIPGP
MUL_3818|M.ulcerans_Agy99           FVTLCKTLGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYDADQVCIIPGP
MLBr_01191|M.leprae_Br4923          FVMLCQMLGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYDADQVCIIPGI
MAV_1650|M.avium_104                FVTLCKTPGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYDADQVCIIPGT
MAB_1512|M.abscessus_ATCC_1997      FVALCKTLGKPVNFVPVIDKDVRRWWRSDSLWQAHDARYTAEQVCIIPGT
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          QAVAGITRVDEPVGELLDRFEQEIVDRVLAAGAEPTPVVSRRQARADVSG
Mvan_4125|M.vanbaalenii_PYR-1       QAVAGITRVDEPVGELLDRFEQEIVDRVLAAGVQPVPVVSRRQARADVSG
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      AAVAGITRVDEPVGELLDRFEQAAVDEVLGAGAEPVEVLSRRQARRDASG
Rv2524c|M.tuberculosis_H37Rv        ASVAGITRMDEPVGELLDRFEQAAIDEVLGAGVEPKDVASRRLGRADVAG
Mb2553c|M.bovis_AF2122/97           ASVAGITRMDEPVGELLDRFEQAAIDEVLGAGVEPKDVASRRLGRADVAG
MMAR_3962|M.marinum_M               AAVAGITRMDEPVGELLDRFERAAIDEVLGSDGDAKAVTSRRLGRPDVTG
MUL_3818|M.ulcerans_Agy99           AAVAGITRMDEPVGELLDRFERAAIDEVLGSDGDAKAVTSRRLGRPDVTG
MLBr_01191|M.leprae_Br4923          AAVAGITQMDEPVGELLDRFEQAAIDEVLAGGAEPVVVMSRRLGRADVAG
MAV_1650|M.avium_104                AAVAGITRMDEPVGELLDRFEQAAIDEALAAGVQPAAVTSRRTGRADVTG
MAB_1512|M.abscessus_ATCC_1997      AAVAGITRVDEPVGELLNRFEQAAVDEVVAAGVEPLPVRSRLRRRWDVEG
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          PLAVVLDSPDVLWAGRTAINPVHRIGAPSEWQVNDVPGKPSATHPNTGAR
Mvan_4125|M.vanbaalenii_PYR-1       PLAVVLDSPDVLWAGRTAINPVHRIGAPGEWQVNDVPGKPSATHPNTGAR
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      PLAVVLDAPDVLWAGRMSVNPVHRIAAPTEWQVREGSDNRSASHPSTGAR
Rv2524c|M.tuberculosis_H37Rv        PLAVVLDAPDVRWAGRTVTNPVHRIADPAEWQVHDGPENPRATHSSTGAR
Mb2553c|M.bovis_AF2122/97           PLAVVLDAPDVRWAGRTVTNPVHRIADPAEWQVHDGPENPRATHSSTGAR
MMAR_3962|M.marinum_M               PLAVVLDAPDVLWAGRTATNPVHRIADPSEWQVHDGPESPRATHTSTGAR
MUL_3818|M.ulcerans_Agy99           PLAVVLDAPDVLWAGRTATNPVHRIADPSEWQVHDGPESPRATHTSTGAR
MLBr_01191|M.leprae_Br4923          PLAVVLDAPDVLWAGRIATNPVHRIADPNEWQVNG---NLSATHSSTGAQ
MAV_1650|M.avium_104                PLAVVLDAPDVQWAGRTAINPVHRIAEPGDWLVHDGPDSRRATHSSTGAR
MAB_1512|M.abscessus_ATCC_1997      PLATVLDAPDVLWSGRIAVNPVHRIAPDGAWQVFEDR---TASHPSTGAR
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          LELAGDGS----------VTLSVPLSDIWIDIRFTLPAATVDGGAPIVTV
Mvan_4125|M.vanbaalenii_PYR-1       LEQATDDSGHV------SVTLSVPLSDIWIDIRFTLPAATVDGGAPIVTV
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      LEVADDQH----------VVLSVPLSGTWIEIRFTLTDVVRSGGAPIVEV
Rv2524c|M.tuberculosis_H37Rv        LQTHGDD-----------VALSVPVSGTWVDIRFTLPANTVDGGTPVIAT
Mb2553c|M.bovis_AF2122/97           LQTHGDD-----------VALSVPVSGTWVDIRFTLPANTVDGGTPVIAT
MMAR_3962|M.marinum_M               LQIQGSD-----------VVLSVPVSATWIDIRFTLPANTVDGGIPVVST
MUL_3818|M.ulcerans_Agy99           LQVQGSD-----------VVLSVPVSATWIDIRFTLPANTVDGGIPVVST
MLBr_01191|M.leprae_Br4923          LQVKSEDQ---------QVVLSVPVSNGWIDIPFTLPTNTVDGGALLVST
MAV_1650|M.avium_104                LQVEGDR-----------VVLSVPVSGTWVEIPFTLPPNTIDGGTPVVST
MAB_1512|M.abscessus_ATCC_1997      LEVIGAAGSATSSEADGIVRLSVPLSGTWVDIDLTLPTTTRDGGTPVVTT
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          EDASKAMRSVLAIAAGVDGPDSLPAVENNTATVTVEWDPQKVADHTGVTA
Mvan_4125|M.vanbaalenii_PYR-1       EDAAKAMRSVLAIAAGVEGPESLPPVQGDTAAVTVEWDPEKVADHTGVTA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      DDAATAMRAVLAIAAGVEGPENLPKVVDNTATVTVDWDPERVADHTGVTA
Rv2524c|M.tuberculosis_H37Rv        EDATSAMRTVLAIAAGVDSPEFLPAVANGTATLTVDWHPERVADHTGVTA
Mb2553c|M.bovis_AF2122/97           EDATSAMRTVLAIAAGVDSPEFLPAVANGTATLTVDWHPERVADHTGVTA
MMAR_3962|M.marinum_M               DDATTAMRSVLAIAAGVDGPESLPPVTDGTATVTVDWDPEKVADHTGVTA
MUL_3818|M.ulcerans_Agy99           DDATTAMRSVLAIAAGVDGPESLPSVTDGTATVTVDWDPEKVADHTGVTA
MLBr_01191|M.leprae_Br4923          EDATSAMRAVLAIVAGVDGPELLSPVKDGTAIVTVDWNPERVADHTGVTA
MAV_1650|M.avium_104                DDAATAMRAVLAIAAGVDGPEFLPKVVDGAATVTVDWDPERVADHTGVTA
MAB_1512|M.abscessus_ATCC_1997      EAASAAMRTVLAVAGGADTPEGLPPVENGIARVVAHWDPERVADHTGVTA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          TFGAPLAPGLTLVPDALVGLCWPAVFSAIGSAVTDDGFPVVEGLLSLVHL
Mvan_4125|M.vanbaalenii_PYR-1       TFGAPLAPGLTLVPDALVGLCWPAVFSAIGSALTEDGFPVVEGLLSLVHL
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      TFGAPLAPTLTVVPDALVGRCWPAVFAAIGSAATEAGFPVIEGLLSLVHL
Rv2524c|M.tuberculosis_H37Rv        TFGEPLAPSLTNVPDALVGPCWPAVFAAIGSAVTDTGEPVVEGLLSLVHL
Mb2553c|M.bovis_AF2122/97           TFGEPLAPSLTNVPDALVGPCWPAVFAAIGSAVTDTGEPVVEGLLSLVHL
MMAR_3962|M.marinum_M               TFGEPLAPSLTTVPDALVGQCWPAVFAAIGSAVTDSGVPVVEGLLSLVHL
MUL_3818|M.ulcerans_Agy99           TFGEPLAPSLTTVPDALVGQCWPAVFAAIGSAVTDSGVPVVEGLLSLVHL
MLBr_01191|M.leprae_Br4923          TFREPLAPSLATVPDALVGACWPAVFSAIGSAVTEAGVLVVEGLLNLLHL
MAV_1650|M.avium_104                TFGEPLAPSLTTVPDALVGLCWPAVFAAIGAAATDTGVPVVEGLLSLVHL
MAB_1512|M.abscessus_ATCC_1997      VLPAPLAPGSSVVPDALVGLCWPAVFAAIGDAKTTDGTGVIEGLLSLVHL
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          DHAAHLLAALPSSTAELTVTATASAATDTEVGRVVPVEVTIA---DSEGT
Mvan_4125|M.vanbaalenii_PYR-1       DHAAHLLTSMPSSKSELTVTATASAATDTEVGRVVPVDVTIA---DSEGT
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      DHAARLLAELPKEPAEFTVTAKASAATDTEVGRVVPVSVEVRN--AADGA
Rv2524c|M.tuberculosis_H37Rv        DHAARVVGQLPTVPAQLTVTATAANATDTDMGRVVPVSVVV---TGADGA
Mb2553c|M.bovis_AF2122/97           DHAARVVGQLPTVPAQLTVTATAANATDTDMGRVVPVSVVV---TGADGA
MMAR_3962|M.marinum_M               DHAARVVGDLPKIPAQLSVTATTSSATDTDMGRVVPVSVTV---AGPDGA
MUL_3818|M.ulcerans_Agy99           DHAARVVGDLPKIPAQLTVTATASNATDTDMGRAVPVSVTV---AGPDGA
MLBr_01191|M.leprae_Br4923          DHAVCVVGKLPTVPAQLTVTATVSLAIDTDMGRVVPVSVTIRDTTGADGA
MAV_1650|M.avium_104                DHAAHMVGKLPTTLAQLTVTATASAAADTDMGRVVPVSVTI---ADAGGQ
MAB_1512|M.abscessus_ATCC_1997      DHAAHLMADLPAESAELTVTATASAAIDTEVGRVVPVDVTVA---AADGA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          VLATLSERFAIRGRTGAVELTDPPRAGGAITDNATDTPRRRRRDVIVTAP
Mvan_4125|M.vanbaalenii_PYR-1       VLATLSERFAIRGRTGAAELADPPRAGGAITDNATDTPRRRRRDVVVNAP
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      LLATLEERFAIRGRTGAAELTDPVRAGGAISDNATDTPRRRRRDVTVGAP
Rv2524c|M.tuberculosis_H37Rv        VIATLEERFAILGRTGSAELADPARAGGAVSANATDTPRRRRRDVTITAP
Mb2553c|M.bovis_AF2122/97           VIATLEERFAILGRTGSAELADPARAGGAVSANATDTPRRRRRDVTITAP
MMAR_3962|M.marinum_M               TIATLEERFAILGRTGTAELSDPVRAGGTVSENATDTPRRRRRDVTLTAP
MUL_3818|M.ulcerans_Agy99           TIATLEERFAILGRTGTAELSDPVRAGGTVSENATDTPRRRRRDVTLTAP
MLBr_01191|M.leprae_Br4923          VLATLEERFVILGRTGTAELTGPVRAGGAISENATDTPRRRRRDVTLTAP
MAV_1650|M.avium_104                VIATLDERFAILGRTGPAELTDPARAGGAVSENATDTPRRRRRDVTITAP
MAB_1512|M.abscessus_ATCC_1997      VLATLQERFAILGRNGAAELTDPVRAGGALSEHEVDTTRRRRRDVKIFAP
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          VDMSAFAVVSGDHNPIHTDRAAALLAGLKMPIVHGMWLSAAAQHAVTATD
Mvan_4125|M.vanbaalenii_PYR-1       VDMSAFAVVSGDHNPIHTDRAAALLAGLKTPIVHGMWLSAAAQHAVTATD
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      VDMRPFAVVSGDHNPIHTDRAAALLAGLEGPIVHGMWLSAAAQHVVTATD
Rv2524c|M.tuberculosis_H37Rv        VDMRPFAVVSGDHNPIHTDRAAALLAGLESPIVHGMWLSAAAQHAVTATD
Mb2553c|M.bovis_AF2122/97           VDMRPFAVVSGDHNPIHTDRAAALLAGLESPIVHGMWLSAAAQHAVTATD
MMAR_3962|M.marinum_M               VDMRPFAVVSGDHNPIHTDRSAALLAGLESPIVHGMWLSAAAQHTVTATD
MUL_3818|M.ulcerans_Agy99           VDMRPFAVVSGDHNPVHTDRSAALLAGLESPIVHGMWLSAAAQHTVTATD
MLBr_01191|M.leprae_Br4923          IDMRPFAVVSGDHNPIHTDRTAALLAGLESPIVHGMWLSAAAQHVVMATD
MAV_1650|M.avium_104                VDMRPFAVVSGDHNPIHTDRAAALLAGLETPIVHGMWLSAAAQHAVTATD
MAB_1512|M.abscessus_ATCC_1997      TDMSAFAVVSGDHNPIHTDKSAALLAGLGSPIVHGMWLSAAAQHVVTSAD
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          GRATPPARLVGWTSRFLGMVLPGDEIEFRVDRVGIDRGAEIVEVAAKVGG
Mvan_4125|M.vanbaalenii_PYR-1       GRATPPARLVGWTSRFLGMVLPGDEIEFRVDRVGIDRGAEIIEVAAKVGG
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      GKPVPPAKLIGWTARFLGMVKPGDQVDFRVDRVGIDVGAEVLEVSARIGS
Rv2524c|M.tuberculosis_H37Rv        GQARPPARLVGWTARFLGMVRPGDEVDFRVERVGIDQGAEIVDVAARVGS
Mb2553c|M.bovis_AF2122/97           GQARPPARLVGWTARFLGMVRPGDEVDFRVERVGIDQGAEIVDVAARVGS
MMAR_3962|M.marinum_M               GKARPPARLVGWTARFLGMVRPGDDVDFRVERVGIDQGAEVLEVSARIGS
MUL_3818|M.ulcerans_Agy99           GKARPPARLVGWTARFLGMVRPGDDVDFRVERVGIDQGAEVLEVSARIGS
MLBr_01191|M.leprae_Br4923          GQARPAARLIGWTARFLGMAHPGDKVDFRVDRIGIDQGAEILEVSARISS
MAV_1650|M.avium_104                GQARPPARLIGWTARFLGMVRPGDEVAFRVDRVGIDQGAEVLEVAARVGS
MAB_1512|M.abscessus_ATCC_1997      ASSTPPRTLIGWTSRFLGMVQPGDEVDIRVDRVGIDSGAEVVEVQAKVGA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          ELVMAATAQLAAPKTVYAFPGQGIQSKGMGMDVRARSKAARKVWDTADKF
Mvan_4125|M.vanbaalenii_PYR-1       ELVMSATAQLAAPKTVYAFPGQGIQSKGMGMDVRARSKAARAVWDTADKF
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      ELVMAATARLAAPKTVYAFPGQGIQHKGMGMEVRARSKAARKVWDSADKF
Rv2524c|M.tuberculosis_H37Rv        DLVMSASARLAAPKTVYAFPGQGIQHKGMGMEVRARSKAARKVWDTADKF
Mb2553c|M.bovis_AF2122/97           DLVMSASARLAAPKTVYAFPGQGIQHKGMGMEVRARSKAARKVWDTADKF
MMAR_3962|M.marinum_M               DLVMSASARLAAPKTVYAFPGQGIQHKGMGMEVRARSKAARKVWDTADRF
MUL_3818|M.ulcerans_Agy99           DLVMSASARLAAPKTVYAFPGQGIQHKGMGMEVRARSKAARKVWDIADRF
MLBr_01191|M.leprae_Br4923          GLVMSATARLAAPKTVYAFPGQGIQHKGMGMDVRARSKAARRVWDDADKF
MAV_1650|M.avium_104                DLVMSATARLAAPRTVYAFPGQGIQHKGMGMDVRARSKAARKVWDKADKF
MAB_1512|M.abscessus_ATCC_1997      DLVMSATARLAAPKTVYAFPGQGIQHKGMGMDVRSRSKAARKVWDKADKF
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          TRETLGFSVLHVVRDNPTSLIASGVHYHHPEGVLYLTQFTQVAMATVAAA
Mvan_4125|M.vanbaalenii_PYR-1       TRETLGFSVLHVVRDNPTSLIASGVHYHHPEGVLYLTQFTQVAMATVAAA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      TRETLGFSVLHVVRDNPTSLIASGVHYHHPDGVLFLTQFTQVAMATVAAA
Rv2524c|M.tuberculosis_H37Rv        TRDTLGFSVLHVVRDNPTSIIASGVHYHHPDGVLYLTQFTQVAMATVAAA
Mb2553c|M.bovis_AF2122/97           TRDTLGFSVLHVVRDNPTSIIASGVHYHHPDGVLYLTQFTQVAMATVAAA
MMAR_3962|M.marinum_M               TRDTLGFSVLHVVRDNPTSLIASGVHYHHPDGVLYLTQFTQVAMATVAAA
MUL_3818|M.ulcerans_Agy99           TRDTLGFSVLHVVRDNPTSLIASGVHYHHPDGVLYLTQFTQVAMATVAAA
MLBr_01191|M.leprae_Br4923          TRSGLGFSVLHVVRDNPTNITANGVHYHHPDGVLYLTQFTQVAMATVAVA
MAV_1650|M.avium_104                TRDTLGFSVLHVVRDNPTSIIASGVHYNHPEGVLYLTQFTQVAMATVAAA
MAB_1512|M.abscessus_ATCC_1997      TRDRLGFSVLHVVKDNPTSLIAGGVHYQHPEGVLYLTQFTQVAMATVAAA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          QVAEMREQGAFVEGAIACGHSVGEYTALACVSGVYPLEALLEVVFHRGSK
Mvan_4125|M.vanbaalenii_PYR-1       QVAEMREQGAFVEGAIACGHSVGEYTALACVSGVYELPALLEVVFHRGSK
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      QVAEMREQGAFVEGAIACGHSVGEYTALACVSGVYELEALLEVVFHRGSK
Rv2524c|M.tuberculosis_H37Rv        QVAEMREQGAFVEGAIACGHSVGEYTALACVTGIYQLEALLEMVFHRGSK
Mb2553c|M.bovis_AF2122/97           QVAEMREQGAFVEGAIACGHSVGEYTALACVTGIYQLEALLEMVFHRGSK
MMAR_3962|M.marinum_M               QVAEMREQGAFVEGAIACGHSVGEYTALACVTGIYELEALLEMVFHRGSK
MUL_3818|M.ulcerans_Agy99           QVAEMREQGAFVEGAIACGHSVGEYTALACVTGIYELEALLEMVFHRGSK
MLBr_01191|M.leprae_Br4923          QVAEMREQGAFVEGAIACGHSVGEYTALACVMGVYELEALLETVFHRGSK
MAV_1650|M.avium_104                QVAEMREQGAFVEDAIACGHSVGEYTALACVTGIYELEALLETVFHRGSK
MAB_1512|M.abscessus_ATCC_1997      QIAEMKESGSFVEDAITCGHSVGEYTALATVSGVIELEGLLEVVFHRGSA
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          MHDIVPRDAQGRSNYRLAAIRPSQIDLDDDDVTAFVAEVSERTGEFLEIV
Mvan_4125|M.vanbaalenii_PYR-1       MHDIVPRDAQGRSNYRLAAIRPSQIDLDDADVKDFVAEISDRTGEFLEIV
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      MHDIVPRDELGRSNYRLAAIRPSQIDLDDADVKDFVAEISERTGEFLEIV
Rv2524c|M.tuberculosis_H37Rv        MHDIVPRDELGRSNYRLAAIRPSQIDLDDADVPAFVAGIAESTGEFLEIV
Mb2553c|M.bovis_AF2122/97           MHDIVPRDELGRSNYRLAAIRPSQIDLDDADVPAFVAGIAESTGEFLEIV
MMAR_3962|M.marinum_M               MHDIVPRDELGRSNYRLAAIRPSQIDLDDNDVPAFVAGIAESTGEFLEIV
MUL_3818|M.ulcerans_Agy99           MHDIVPRDELGRSNYRLAAIRPSQIDLDDNDVPAFVAGIAESTGEFLEIV
MLBr_01191|M.leprae_Br4923          MHDIVLRDELGRSNYRLAAIRPSQIGLPDDEVPAFVRGIAESTGEFLEIV
MAV_1650|M.avium_104                MHDIVPRDELGRSNYRLAAIRPSQIDLPDDEVPAFVAGIAERTGEFLEIV
MAB_1512|M.abscessus_ATCC_1997      MHDIVPRDELGRSNYRLAAIRPSQIGLDDADVDAFVAEIAERSGEFLQIV
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          NFNLRGAQYAIAGTVAGLEALEEEVERRREISGGKRSFILVPGIDVPFHS
Mvan_4125|M.vanbaalenii_PYR-1       NYNLRGSQYAIAGTVAGLEALEAEVERRRELSGGKRSFILVPGIDVPFHS
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      NFNLRGSQYAIAGTVAGLEALEEEIERRRQITGGKRSFILVPGIDVPFHS
Rv2524c|M.tuberculosis_H37Rv        NFNLRGSQYAIAGTVRGLEALEAEVERRRELTGGRRSFILVPGIDVPFHS
Mb2553c|M.bovis_AF2122/97           NFNLRGSQYAIAGTVRGLEALEAEVERRRELTGGRRSFILVPGIDVPFHS
MMAR_3962|M.marinum_M               NFNLRGSQYAIAGTVRGLEALEAEVERRRELSGGRRSFILVPGIDVPFHS
MUL_3818|M.ulcerans_Agy99           NFNLRGSQYAIAATVRGLEALEAEVERRRELSGGRRSFILVPGIDVPFHS
MLBr_01191|M.leprae_Br4923          NFNLRGSQYAIAGTVHGLEALEAEVERRRELTGGRRSFILVPGIDVPFHS
MAV_1650|M.avium_104                NFNLRGSQYAIAGTVRGLEALEEEVERRREITGGKRSFILVPGIDVPFHS
MAB_1512|M.abscessus_ATCC_1997      NFNLRGSQYAIAGTVRGLELLEAEVERRREEFGGRRSFILVPGIDVPFHS
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          SVLRVGVADFRRALERVMPTDADPELLIGRYIPNLVPRPFTLDRDFIEEI
Mvan_4125|M.vanbaalenii_PYR-1       SVLRVGVADFRRALERVMPNPNDPNLLVGRYIPNLVPRPFTLDRDFIQEI
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      SVLRVGVADFRRSLERVMPRDKDPELIIGRYIPNLVPRPFTLDRDFIQEI
Rv2524c|M.tuberculosis_H37Rv        RVLRVGVAEFRRSLDRVMPRDADPDLIIGRYIPNLVPRLFTLDRDFIQEI
Mb2553c|M.bovis_AF2122/97           RVLRVGVAEFRRSLDRVMPRDADPDLIIGRYIPNLVPRLFTLDRDFIQEI
MMAR_3962|M.marinum_M               RVLRVGVAEFRRSLDRVMPRDADPDLIIGRYIPNLVPRLFNLDRDFIQEI
MUL_3818|M.ulcerans_Agy99           RVLRVGVAEFRRSLDRVMPRDADPDLIIGRYIPNLVPRLFNLDRDFIQEI
MLBr_01191|M.leprae_Br4923          RVLRVGVAEFRRSLDRVLPQDQDPDWIIGRYIPNLVPRPFTLARDFIQEI
MAV_1650|M.avium_104                RVLRVGVAEFRRSLDRVMPRDKDPDIIIGRYIPNLVPRPFTLDRDFIQEI
MAB_1512|M.abscessus_ATCC_1997      KVLRVGVAEFRRSLERVLPMDGDPNLIIGKYIPNLVPKPFTLDREFIQEI
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          RDLVPAEPLDEVLADYDTWRNERPRELMRKIVIELLAWQFASPVRWIETQ
Mvan_4125|M.vanbaalenii_PYR-1       RDLVPAEPLDEILADYDTWRNERPSELCRKIVIELLAWQFASPVRWIETQ
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      RDLVPAEPLDEVLADYDTWRNEKPKELCRKVVIELLAWQFASPVRWIETQ
Rv2524c|M.tuberculosis_H37Rv        RDLVPAEPLDEILADYDTWLRERPREMARTVFIELLAWQFASPVRWIETQ
Mb2553c|M.bovis_AF2122/97           RDLVPAEPLDEILADYDTWLRERPREMARTVFIELLAWQFASPVRWIETQ
MMAR_3962|M.marinum_M               RDLVPAEPLDEILADYDTWIRERPRELARTVFIELLAWQFASPVRWIETQ
MUL_3818|M.ulcerans_Agy99           RDLVPAEPLDEILADYDTWIRERPRELARTVFIELLAWQFASPVRWIETQ
MLBr_01191|M.leprae_Br4923          RDLVPAEPLDDILADYDTWRRERPSEMARRVLIELLAWQFASPVRWIETQ
MAV_1650|M.avium_104                RDLVPAEPLDPILADYDTWLAERRIEMARTVLIELLAWQFASPVRWIETQ
MAB_1512|M.abscessus_ATCC_1997      RDLVPAEPLDEVLANYDTWRNEKPVLLCRKVLIELLAWQFASPVRWIETQ
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          DLLFIEEAAGGLGVERFVEIGVKNAPTVAGLATNTLKLPEYSHNTTEVLN
Mvan_4125|M.vanbaalenii_PYR-1       DLLFIEEAAGGLGVERFVEIGVKNAPTVAGLAANTLKLPEYSHNTTEVLN
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      DLLFIEEAAGGLGVERFVEIGVKSAPTVAGLATNTLKLPEYSHSTVEVLN
Rv2524c|M.tuberculosis_H37Rv        DLLFIEEAAGGLGVERFVEIGVKSSPTVAGLATNTLKLPEYAHSTVEVLN
Mb2553c|M.bovis_AF2122/97           DLLFIEEAAGGLGVERFVEIGVKSSPTVAGLATNTLKLPEYAHSTVEVLN
MMAR_3962|M.marinum_M               DLLFIEEAAGGLGVERFVEIGVKTSPTVAGLATNTLKLPEYAHSTVEVLN
MUL_3818|M.ulcerans_Agy99           DLLFIEEAAGGLGVERFVEIGVKTSPTVAGLATNTLKLPEYAHSTVEVLN
MLBr_01191|M.leprae_Br4923          DLLFTEEAAGGLGVERFVEIGVKSAPTVAGLATDTLKLPEYSHNTVEVLN
MAV_1650|M.avium_104                DLLFTEEAAGGLGVERFVEIGVKSAPTVAGLATNTLKLPEYAHSTVEVLN
MAB_1512|M.abscessus_ATCC_1997      DLLFTEEAAGGLGVERFVEVGVKSAPTVTGLANNTLKLPEYSHSSIEVLN
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          AERDAAVLFATDTDPEPDFEDAAPEAP--AAAAPAEAAPAEAAPAAPAPA
Mvan_4125|M.vanbaalenii_PYR-1       AERDAAVLFATDTDPEPDPEDDVADATPAAETAPAEAVPAEAAPAAPAPA
TH_1319|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4757|M.smegmatis_MC2_155      SERDAAVLFATDTDPEPEPEADEPTADAPAEAAPAAAA----APAPVAAP
Rv2524c|M.tuberculosis_H37Rv        AERDAAVLFATDTDPEPEPEEDE----PVAESPAPDVVSEAAP-VAPAAS
Mb2553c|M.bovis_AF2122/97           AERDAAVLFATDTDPEPEPEEDE----PVAESPAPDVVSEAAP-VAPAAS
MMAR_3962|M.marinum_M               AERDAAVLFATDTDPEPEPEPEA----EEPAAEAGDAAAAPAPAAAPAAP
MUL_3818|M.ulcerans_Agy99           AERDAAVLFATDTDPEPEPEPEA----EEPAAEAGDAAAAAAPAAAPAAP
MLBr_01191|M.leprae_Br4923          VERDAAVLFATDTDPELEPEPEN----VSDASAALPAESALALGTVAPAP
MAV_1650|M.avium_104                AERDAAVLFATDTDPEPEPEADE----ASDSAVPASSDGAPMSDVAPAPA
MAB_1512|M.abscessus_ATCC_1997      VERDHAVLFGTDSDPEPEPEIEEP-----VESTAAASGSVEAAPAPAAAP
                                                                                      

Mflv_2532|M.gilvum_PYR-GCK          AAPSGGPRPEDLTFDAADATMALIALSAKIRIDQIEALDSIESITDGASS
Mvan_4125|M.vanbaalenii_PYR-1       AAPSGGPRPDDLAFDAADATMALIALSAKIRIDQIEALDSIESITDGASS
TH_1319|M.thermoresistible__bu      --------------------MALIALSAKMRLDQIEPLDSIESITDGASS
MSMEG_4757|M.smegmatis_MC2_155      AAPSGGPRPDDITFDAADATVALIALSAKMRIDQIEALDSIESITDGASS
Rv2524c|M.tuberculosis_H37Rv        SA---GPRPDDLVFDAADATLALIALSAKMRIDQIEELDSIESITDGASS
Mb2553c|M.bovis_AF2122/97           SA---GPRPDDLVFDAADATLALIALSAKMRIDQIEELDSIESITDGASS
MMAR_3962|M.marinum_M               SG---GPRPDDIGFDAADATLALIALSAKMRLDQIEELDSIESITDGASS
MUL_3818|M.ulcerans_Agy99           SG---GPRPDDIGFDAADATLALIALSAKMRLDQIEQLDSIESITDGASS
MLBr_01191|M.leprae_Br4923          VVPS-GPRPEDISFGAADATLALIALSAKMRLDQIEEMDSIESITDGASS
MAV_1650|M.avium_104                AAPSGAPRPEDIPFDAADATLALIALSAKMRIDQIEELDSIESITDGASS
MAB_1512|M.abscessus_ATCC_1997      AAPSGGPRPDDLGFDASDATLALIALSTKMRIDQIEPVDSIESLTDGASS
                                                        :******:*:*:**** :*****:******

Mflv_2532|M.gilvum_PYR-GCK          RRNQMLVDLGSELNLGAIDGAAEADLAGLKGQVTKLARTYKPFGPVLSDA
Mvan_4125|M.vanbaalenii_PYR-1       RRNQMLVDLGSELNLGAIDGAAEADLAGLKGQVTKLARTYKPFGPVLSDA
TH_1319|M.thermoresistible__bu      RRNQLLVDLGSELNLGAIDGAAEADLGSLKGQVTKLARTYKPFGPVLSDA
MSMEG_4757|M.smegmatis_MC2_155      RRNQLLVDLGSELNLGAIDGAAEADLGALKGQVTKLARTYKPFGPVLSDA
Rv2524c|M.tuberculosis_H37Rv        RRNQLLVDLGSELNLGAIDGAAESDLAGLRSQVTKLARTYKPYGPVLSDA
Mb2553c|M.bovis_AF2122/97           RRNQLLVDLGSELNLGAIDGAAESDLAGLRSQVTKLARTYKPYGPVLSDA
MMAR_3962|M.marinum_M               RRNQLLVDLGSELNLGAIDGAAEADLAGLRSQVTKLARTYKPYGPVLSDA
MUL_3818|M.ulcerans_Agy99           RRNQLLVDLGSELNLGAIDGAAEADLAGLRSKVTKLARTYKPYGPVLSDA
MLBr_01191|M.leprae_Br4923          RRNQLLVDLGSELSLGAIDGVAEADLAGLRSQVTKLARTYKPYGPVLSEL
MAV_1650|M.avium_104                RRNQLLVDLGSELNLGAIDGAAEADLAGLRTQVTKLARTYKPYGPVLSDA
MAB_1512|M.abscessus_ATCC_1997      RRNQLLVDLGSELNLSAIDGAAEADLSGLRVQVTKLARTYKPFGPVLSDS
                                    ****:********.*.****.**:**..*: :**********:*****: 

Mflv_2532|M.gilvum_PYR-GCK          INDQLRTVLGPSGKRPAYIVERVKKTWELGDGWGKHVTVEVALGTREGTS
Mvan_4125|M.vanbaalenii_PYR-1       INDQLRTVFGPSGKRPAYIAERVKKTWELGDGWAKHATVEVALGTREGSS
TH_1319|M.thermoresistible__bu      INDQLRTVLGPSGKRPAYIAERVAKTWELGEGWAKHVTVEVALGTREGSS
MSMEG_4757|M.smegmatis_MC2_155      INDQLRTVLGPSGKRPAYITERVTKTWELGPGWAKHVTVEFALGTREGSS
Rv2524c|M.tuberculosis_H37Rv        INDQLRTVLGPSGKRPGAIAERVKKTWELGEGWAKHVTVEVALGTREGSS
Mb2553c|M.bovis_AF2122/97           INDQLRTVLGPSGKRPGAIAERVKKTWELGEGWAKHVTVEVALGTREGSS
MMAR_3962|M.marinum_M               INDQLRTVLGPSGKRPGAIAERVKKTWELGDGWAKHVTVEVALGTREGSS
MUL_3818|M.ulcerans_Agy99           INDQLRTVLGPSGKRPGAIAERVKKTWELGDGWAKHVTVEVALGTREGSS
MLBr_01191|M.leprae_Br4923          INDQLRSALGPSGKRPGVIAERVKKIWELGDGWVKHVTVEIALGTREGTS
MAV_1650|M.avium_104                INDQLRTVLGPSGKRPGAIAERVKKTWELGEGWAKHVTVEVALGTREGTS
MAB_1512|M.abscessus_ATCC_1997      INDQLKTVFGPSGKRPTAIAERVTKTWELGPGWVKHVTVELALGTREGTS
                                    *****::.:*******  *.*** * **** ** **.***.*******:*

Mflv_2532|M.gilvum_PYR-GCK          VRGGALGGLHDGALADAAAVDKAIDAAVAAVGARRGVPVSLPSAAGGGGG
Mvan_4125|M.vanbaalenii_PYR-1       VRGGALGGLHDGALADAAAVDKAIDAAVAAIGARKGVSVSLPSAAGGGGG
TH_1319|M.thermoresistible__bu      VRGGDLGGLHDGALADAAAVDKVIDAAVGAVAARHGVAVSLPSSGGAGGG
MSMEG_4757|M.smegmatis_MC2_155      VRGGDLGGLHAGALASAADVDKVIDGAVAAVAARRGISVSLPSAGGASGG
Rv2524c|M.tuberculosis_H37Rv        VRGGAMGHLHEGALADAASVDKVIDAAVASVAARQGVSVALPSAGSGGG-
Mb2553c|M.bovis_AF2122/97           VRGGAMGHLHEGALADAASVDKVIDAAVASVAARQGVSVALPSAGSGGG-
MMAR_3962|M.marinum_M               VRGGALGNLHEGALADAASVDKVVDAAVASVAARRGVAVALPSAGGGGG-
MUL_3818|M.ulcerans_Agy99           VRGGALGNLHEGALADAASVDKVVDAAVASVAARRGVAVALPSAGGGGG-
MLBr_01191|M.leprae_Br4923          VRGGPLGNLNEGALADVDSVDKAVDAAVASVAARHGVVVALPSAGSGGS-
MAV_1650|M.avium_104                VRGGALGHLHEGALADAAAVDKAIDAAVAAVAARRGITVALPSAGGGGAG
MAB_1512|M.abscessus_ATCC_1997      VRGGDLGGLAPSTLADGNAVDTAIDAAVAAVAGRHGVGVTLPSAGGGGG-
                                    **** :* *  .:**.   **..:*.**.::..*:*: *:***:..... 

Mflv_2532|M.gilvum_PYR-GCK          GVVDSAALGEFAEQVTGRNGVLASAARLILDQLGHSQVA--SAPESTADA
Mvan_4125|M.vanbaalenii_PYR-1       -VVDSAALGEFAEQVTGPDGVLASAARTILDQLGLGNQF--VTPDASADA
TH_1319|M.thermoresistible__bu      -MVDSAALGEFAEQVTGRDGVLASAARLVLNQLGFDDTV--SVPEQATDS
MSMEG_4757|M.smegmatis_MC2_155      -VVDSAALGEFAEKVTGPDGVLASAARLVLNQLGLSDVV--TTPEAATDA
Rv2524c|M.tuberculosis_H37Rv        ATIDAAALSEFTDQITGREGVLASAARLVLGQLGLDDPV--NALPAAPDS
Mb2553c|M.bovis_AF2122/97           ATIDAAALSEFTDQITGREGVLASAARLVLGQLGLDDPV--NALPAAPDS
MMAR_3962|M.marinum_M               ATVDAAALAEFTDQITGRDGVLASAARLVLGQLGLDAPA--TALPAATDA
MUL_3818|M.ulcerans_Agy99           ATVDAAALAEFTDQITGRDGVLASAARLVLGQLGLDAPA--TALPAATDA
MLBr_01191|M.leprae_Br4923          ATVDVAALSEFTDQITGHDGVLASAARLVLGQLGLDGPV--TAAPATTDT
MAV_1650|M.avium_104                ATIDAVALGEFTEQITGRDGVLASAARLVLNQLGLDEPAGAAAASAATDA
MAB_1512|M.abscessus_ATCC_1997      ATVDAAALSEFTDQITGRDGVLASAARLVLDQLGLSAPV--AVPDGATDT
                                      :* .**.**::::** :******** :*.*** .      .   :.*:

Mflv_2532|M.gilvum_PYR-GCK          ELIDLVTAELGSDWPRLVAPVFDSRKAVVLDDRWASAREDLVKIWLMDED
Mvan_4125|M.vanbaalenii_PYR-1       ELIDLVTAELGSDWPRLVAPVFDGRKAVVLDDRWASAREDLARIWLMDEG
TH_1319|M.thermoresistible__bu      ELIDLVTAELGSDWPRLVAPAFDARKAVLLDDRWASAREDLVKIWLADED
MSMEG_4757|M.smegmatis_MC2_155      ELIDLVTAELGSDWPRLVAPTFDARKAVVFDDRWASAREDLVKLWLAEEG
Rv2524c|M.tuberculosis_H37Rv        ELIDLVTAELGADWPRLVAPVFDPKKAVVFDDRWASAREDLVKLWLTDEG
Mb2553c|M.bovis_AF2122/97           ELIDLVTAELGADWPRLVAPVFDPKKAVVFDDRWASAREDLVKLWLTDEG
MMAR_3962|M.marinum_M               DLIELVTAELGSDWPRLVAPVFDGKKAVVFDDRWASAREDLVKLWLTDEG
MUL_3818|M.ulcerans_Agy99           DLIELVTAELGSDWPRLVAPVFDGKKAVVFDDRWASAREDLVKLWLTDEG
MLBr_01191|M.leprae_Br4923          GLIDLVTAELSTDWPRLVAPVFDVKKAVVFDDRWASAREDLVRLWLNDEG
MAV_1650|M.avium_104                ELIDLVTAELGADWPRLVAPVFDPKKAVLFDDRWASAREDLVKLWLADEG
MAB_1512|M.abscessus_ATCC_1997      ELVELVSAELGSDWPRLVAPTFDGKKAVVFDDRWASAREDLARLWITEES
                                     *::**:***.:********.** :***::***********.::*: :*.

Mflv_2532|M.gilvum_PYR-GCK          DIDADWARLSSRFEGAGHVVGTQATYWQGKALAVGRNVHASLYARAAAGA
Mvan_4125|M.vanbaalenii_PYR-1       DIDADWARLSERFEGAGHVVGTQATYWQGKALAAGRTVHASLYARAAAGA
TH_1319|M.thermoresistible__bu      DIDADWPRLAERFEGTGHVVATQANWWQGKALAAGRNVHASLFGRIAAGA
MSMEG_4757|M.smegmatis_MC2_155      DIDAQWEQLSQRFEGTGHVVATQANWWQGKALAAGRNVHASLFGRIAAGA
Rv2524c|M.tuberculosis_H37Rv        DIDADWPRLAERFEGAGHVVATQATWWQGKSLAAGRQIHASLYGRIAAGA
Mb2553c|M.bovis_AF2122/97           DIDADWPRLAERFEGAGHVVATQATWWQGKSLAAGRQIHASLYGRIAAGA
MMAR_3962|M.marinum_M               DIDADWARLSQRFEGAGHVVATQATWWQGKSLAAGRQIHASLYGRIAAGA
MUL_3818|M.ulcerans_Agy99           DIDADWARLSQRFEGAGHVVATQATWWQGKSLAAGRQIHASLYGRIAAGA
MLBr_01191|M.leprae_Br4923          EIEAQWSHLSERFEGAGHVVATQATWWQGKSLAAGRQIHASLYGRIAAGA
MAV_1650|M.avium_104                DIDSQWLHLSERFEGAGHVVATQATWWQGKALSAGRAVHASLYGRIAAGA
MAB_1512|M.abscessus_ATCC_1997      EIDGQWESLGLQFEGAGHAVATQANWWQGKSLAQGRNVHASLYGRIAAGA
                                    :*:.:*  *. :***:**.*.***.:****:*: ** :****:.* ****

Mflv_2532|M.gilvum_PYR-GCK          ENPGKGRYSDEVAVVTGASKGSIAASVVAQLLDGGATVVATTSRLDDSRL
Mvan_4125|M.vanbaalenii_PYR-1       ENPGKGRYHDEVAVVTGASKGSIAASVVAQLLDGGATVVATTSKLDDNRL
TH_1319|M.thermoresistible__bu      ENPGSGRYSDEVAVVTGASKGSIAAAVVAQLLDGGATVIATTSRLDDDRL
MSMEG_4757|M.smegmatis_MC2_155      ENPGKGRYSDEVAVVTGASKGSIAASVVGQLLDGGATVIATTSRLDDDRL
Rv2524c|M.tuberculosis_H37Rv        ENPEPGRYGGEVAVVTGASKGSIAASVVARLLDGGATVIATTSKLDEERL
Mb2553c|M.bovis_AF2122/97           ENPEPGRYGGEVAVVTGASKGSIAASVVARLLDGGATVIATTSKLDEERL
MMAR_3962|M.marinum_M               ENPDPGPDSSEVAVVTGASKGSIAASVVARLLDGGATVIATTSKLDDERL
MUL_3818|M.ulcerans_Agy99           ENPDPGPDSSEVAVVTGASKGSIAASVVARLLDGGATVIATTSKLDDERL
MLBr_01191|M.leprae_Br4923          QNPDRGLYSSEIAVVTGASKGSIAASVAARLLDGGATVIATTSKLDEERI
MAV_1650|M.avium_104                ENPDPGRYSHEVAVVTGASKGSIASSVVARLLDGGATVIATTSKLDDERL
MAB_1512|M.abscessus_ATCC_1997      ESPEQGKWGSEVAVVTGASKGSIAASVVAALLSGGATVIATTSRLDEDRL
                                    :.*  *    *:************::*.. **.*****:****:**:.*:

Mflv_2532|M.gilvum_PYR-GCK          GFYRQLYRDNARFGAKLWVLPANMASYNDIDALVDWIGTEQSESLGPKSI
Mvan_4125|M.vanbaalenii_PYR-1       AFYRQLYRDSARFGAKLWVLPANMASYNDIDALVEWIGTEQSESLGPKSV
TH_1319|M.thermoresistible__bu      EFYKSLYRDNARFDAKLWVVPANMASYSDIDALVEWIGSEQVENLGPQSI
MSMEG_4757|M.smegmatis_MC2_155      AFYKQLYRDHARFDATLWVVPANMASYSDIDKLVEWVGTEQTESLGPQSI
Rv2524c|M.tuberculosis_H37Rv        AFYRTLYRDHARYGAALWLVAANMASYSDVDALVEWIGTEQTESLGPQSI
Mb2553c|M.bovis_AF2122/97           AFYRTLYRDHARYGAALWLVAANMASYSDVDALVEWIGTEQTESLGPQSI
MMAR_3962|M.marinum_M               AFYRTLYRDHARYGAALWVVAANMASYSDIDALVEWVGSEQTESLGPQSI
MUL_3818|M.ulcerans_Agy99           AFYRTLYRDHARYGAALWVVAANMASYSDIDALVEWVGSEQTESLGPQSI
MLBr_01191|M.leprae_Br4923          TFYRALYRDHARYGAALWVVAANMASYSDIDALVEWIGNEQTESLGPQSI
MAV_1650|M.avium_104                AFYRGLYRDHARYGAALWVVAANMASYSDIDALVEWIGTEQTESLGPQSI
MAB_1512|M.abscessus_ATCC_1997      AFYRNLYRESARFGAKLWVVPANMASYADIDALVQWVGTEQSESLGPMSI
                                     **: ***: **:.* **::.****** *:* **:*:*.** *.*** *:

Mflv_2532|M.gilvum_PYR-GCK          HIKDALTPTLLFPFAAPRVGGDLSEAGARAEMEMKVLLWAVQRLIAGLSH
Mvan_4125|M.vanbaalenii_PYR-1       HIKDALTPTLLFPFAAPRVGGDLSDAGSRSEMEMKVLLWAVQRLIGGLSH
TH_1319|M.thermoresistible__bu      HLKDAQTPTLLFPFAAPRVAGDMSEAGSRAEMEMKVLLWAVERLITGLAT
MSMEG_4757|M.smegmatis_MC2_155      HLKDAQTPTLLFPFAAPRVAGDMSEVGSRAEMEMKVLLWAVQRLISGLSK
Rv2524c|M.tuberculosis_H37Rv        HIKDAQTPTLLFPFAAPRVVGDLSEAGSRAEMEMKVLLWAVQRLIGGLST
Mb2553c|M.bovis_AF2122/97           HIKDAQTPTLLFPFAAPRVVGDLSEAGSRAEMEMKVLLWAVQRLIGGLST
MMAR_3962|M.marinum_M               HIKDAQTPTLLFPFAAPRVVGDLSEAGSRSEMEMKVLLWAVQRLIGGLST
MUL_3818|M.ulcerans_Agy99           HIKDAQTPTLLFPFAAPRVVGDLSEAGSRSEMEMKVLLWAVQRLIGGLST
MLBr_01191|M.leprae_Br4923          HIKDAQTPTLLFPFAAPRVIGDLSEAGARSEIEMKVLLWAVQRLIVGLSK
MAV_1650|M.avium_104                HIKDAQTPTLLFPFAAPRVAGDLSEAGSRSEMEMKVLLWAVQRLIGGLSK
MAB_1512|M.abscessus_ATCC_1997      HLKDAQTPTLLFPFAAPKVVGDLSEAGSRAEMEMKVLLWAVQRLIGGLSA
                                    *:*** ***********:* **:*:.*:*:*:*********:*** **: 

Mflv_2532|M.gilvum_PYR-GCK          IGADRDIAARLHVVLPGSPNRGMFGGDGAYGESKSALDAVVSRWKAETSW
Mvan_4125|M.vanbaalenii_PYR-1       ISADRDIAARLHVVLPGSPNRGMFGGDGAYGESKAALDAVVSRWKAETSW
TH_1319|M.thermoresistible__bu      IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKAALDAVVTRWKAESSW
MSMEG_4757|M.smegmatis_MC2_155      IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDALENRWSAEKSW
Rv2524c|M.tuberculosis_H37Rv        IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSW
Mb2553c|M.bovis_AF2122/97           IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSW
MMAR_3962|M.marinum_M               IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSW
MUL_3818|M.ulcerans_Agy99           IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSW
MLBr_01191|M.leprae_Br4923          IGTERDVASRLHVVLPGSPNRGMFGGDGAYGEAKSALDAVVSRWHAESSW
MAV_1650|M.avium_104                IGAERDIASRLHVVLPGSPNRGMFGGDGAYGEAKSALDALVSRWHAESSW
MAB_1512|M.abscessus_ATCC_1997      IGAERDIASRLHVVLPGSPNRGMFGGDGAYGESKAALDALVTRWKAESSW
                                    *.::**:*:***********************:*:****: .** **.**

Mflv_2532|M.gilvum_PYR-GCK          AQRVSLAHALIGWTRGTGLMGHNDVIVDAVEEAGVTTYSTEQMAAMLLDL
Mvan_4125|M.vanbaalenii_PYR-1       AQRVSLAHALIGWTRGTGLMGHNDVIVDAVEEAGVTTYSTEQMASMLLDL
TH_1319|M.thermoresistible__bu      AQRVSLAHALIGWTKGTGLMGHNDAIVDAVEAAGLTTYTTSEMASKLLSL
MSMEG_4757|M.smegmatis_MC2_155      AERVSLAHALIGWTKGTGLMGQNDAIVSAVEEAGVTTYTTDEMAAMLLDL
Rv2524c|M.tuberculosis_H37Rv        AARVSLAHALIGWTRGTGLMGHNDAIVAAVEEAGVTTYSTDEMAALLLDL
Mb2553c|M.bovis_AF2122/97           AARVSLAHALIGWTRGTGLMGHNDAIVAAVEEAGVTTYSTDEMAALLLDL
MMAR_3962|M.marinum_M               AARVSLAHALIGWTRGTGLMGHNDAIVSAVEEAGVTTYSTDEMAAMLLGL
MUL_3818|M.ulcerans_Agy99           AARVSLAHALIGWTRGTGLMGHNDAIVSAVEEAGVTTYSTDEMAAMLLGL
MLBr_01191|M.leprae_Br4923          AARVSLAHALIGWTRGTGLMGHNDVIVSAVEEAGVTTYSTDEMAAMLLDL
MAV_1650|M.avium_104                AARVSLAHALIGWTRGTGLMGHNDAIVDAVEQAGVTTYSTDEMAAMLLDL
MAB_1512|M.abscessus_ATCC_1997      ASRVSLAHALIGWTRGTGLMGHNDAIVTAVEEAGVTTYSTADMASMLLAL
                                    * ************:******:**.** *** **:***:* :**: ** *

Mflv_2532|M.gilvum_PYR-GCK          CDVEHKVAAAREPVLADLTGGLAEVELDLSALAAKARENAAVADEDETV-
Mvan_4125|M.vanbaalenii_PYR-1       CDVETKVAAAREPVLADLTGGLAEVELDLSALATKAREEATSTSADEDG-
TH_1319|M.thermoresistible__bu      CDAEAKAAAAREPIEADFTGGLGDIDIDMAELAAKAREEHAASTQQD---
MSMEG_4757|M.smegmatis_MC2_155      CTVETKVAAAGAPVKVDLTGGLGDIKIDMAELAAKAREEMSGAADES---
Rv2524c|M.tuberculosis_H37Rv        CDAESKVAAARSPIKADLTGGLAEANLDMAELAAKAREQMSAAAAVDED-
Mb2553c|M.bovis_AF2122/97           CDAESKVAAARSPIKADLTGGLAEANLDMAELAAKAREQMSAAAAVDED-
MMAR_3962|M.marinum_M               CDVESKVAAASTPIKADLTGGLAEANLDMAELAAKAREEMSTEATADDE-
MUL_3818|M.ulcerans_Agy99           CDVESKVAAASTPIKADLTGGLAEANLDMAELAAKAREEMSTEATADDE-
MLBr_01191|M.leprae_Br4923          CNAESKVAAAGTPITVDLTGGLGEVDLDMAELAAKAREDHAAQAAEDEAT
MAV_1650|M.avium_104                CDVESKVAAASAPIKADLTGGLGEADLDMAELAAKAREQATGAEPAADD-
MAB_1512|M.abscessus_ATCC_1997      CTPEARVQAAQAPVEKDLTGGLAEVQLDMAELAAKAREDLESRAAKSNEI
                                    *  * :. **  *:  *:****.: .:*:: **:****:           

Mflv_2532|M.gilvum_PYR-GCK          EDEAADHTIAALPSPPRPPAPAPVPDWADLDVDPADLVVIVGGAELGPYG
Mvan_4125|M.vanbaalenii_PYR-1       DDEAADHLIAALPSPPRPVTPAHAPEWADLDVDPADLVVIVGGAELGPYG
TH_1319|M.thermoresistible__bu      DEEPAAATIAALPSPPRVPVPAPAPQWADLDIDPADMVVIVGGAELGPYG
MSMEG_4757|M.smegmatis_MC2_155      DDEAPAGTIRALPSPPRGYNPAPAPEWDDLDVDPADLVVIVGGAELGPYG
Rv2524c|M.tuberculosis_H37Rv        --AEAPGAIAALPSPPRGFTPAPPPQWDDLDVDPADLVVIVGGAEIGPYG
Mb2553c|M.bovis_AF2122/97           --AEAPGAIAALPSPPRGFTPAPPPQWDDLDVDPADLVVIVGGAEIGPYG
MMAR_3962|M.marinum_M               --ESTEGAIPALPSPPRGYTPAPPPHWDDLDVDPSDLVVIVGGAELGPYG
MUL_3818|M.ulcerans_Agy99           --ESTEGAIPALPSPPRGYTPAPPPHWDDLDVDPSDLVVIVGGAELGPYG
MLBr_01191|M.leprae_Br4923          EASEVAGTIAALPSPPRGYTPASP-HWDDLDVDPADLVVIVGGAEIGPYG
MAV_1650|M.avium_104                --GPTPGTIAALPSPPRGFTPAPPPEWADLDVDPADLVVIVGGAELGPYG
MAB_1512|M.abscessus_ATCC_1997      DDEDDPNVIAALPSPPRGYTSTLPPEWADLDVDPADLVVIVGGGELGPLG
                                            * *******   .:   .* ***:**:*:******.*:** *

Mflv_2532|M.gilvum_PYR-GCK          SSRTRFEMEVDNELSAAGVLELAWTTGLIKWEDDPQPGWYDTESGDLVDE
Mvan_4125|M.vanbaalenii_PYR-1       SSRTRFEMEVDNELSAAGVLELAWTTGLVKWEDDPQPGWYDTESGDLVDE
TH_1319|M.thermoresistible__bu      SSRTRYEMEVDNELSAAGVLELAWTTGMITWENDPQPGWYDTETGELVPE
MSMEG_4757|M.smegmatis_MC2_155      SSRTRFEMEVSGELSAAGVLELAWTTGMVKWEDDPKAGWYDTETGELVPE
Rv2524c|M.tuberculosis_H37Rv        SSRTRFEMEVENELSAAGVLELAWTTGLIRWEDDPQPGWYDTESGEMVDE
Mb2553c|M.bovis_AF2122/97           SSRTRFEMEVENELSAAGVLELAWTTGLIRWEDDPQPGWYDTESGEMVDE
MMAR_3962|M.marinum_M               SSRTRFEMEVENELSAAGVLELAWTTGLVRWEDDPQPGWYDTGTGELVDE
MUL_3818|M.ulcerans_Agy99           SSRTRFEMEVENELSAAGVLELAWTTGLVRWEDDPQPGWYDTGTGELVDE
MLBr_01191|M.leprae_Br4923          SSRTRFEMEVAGELSAAGVLELVWTTGLIRWEDDPQPGWYDTESGELVDE
MAV_1650|M.avium_104                SSRTRFEMEVDNELSAAGVLELAWTTGLIRWEDDPQPGWYDTESGELVDE
MAB_1512|M.abscessus_ATCC_1997      SSRTRYEMEVDDELSAAGVLELAWTTGLVKWENDPEAGWYDTETGELVPE
                                    *****:**** .**********.****:: **:**:.***** :*::* *

Mflv_2532|M.gilvum_PYR-GCK          ADLVERYHDVVVERVGIREFVGDAAIDPDHSAPLLVSVFLDKDFSFVVSS
Mvan_4125|M.vanbaalenii_PYR-1       SELVERYHDAVVERCGIREFVDDGAIDPDHGSPLLVSVFLDKDFRFVVSS
TH_1319|M.thermoresistible__bu      EELVERYHDAVVERCGIREFVDDGAIDPDHASPLLVSVFLDKDFTFVVSS
MSMEG_4757|M.smegmatis_MC2_155      CEIVERYHDAVVERCGIREFVDDGAIDPDHASPLLVSVFLDKDFTFVVSS
Rv2524c|M.tuberculosis_H37Rv        SELVQRYHDAVVQRVGIREFVDDGAIDPDHASPLLVSVFLEKDFAFVVSS
Mb2553c|M.bovis_AF2122/97           SELVQRYHDAVVQRVGIREFVDDGAIDPDHASPLLVSVFLEKDFAFVVSS
MMAR_3962|M.marinum_M               AELVERYHDTVVERVGIREFVDDGTIDSDHSSPLLVSVFLDKDFSFVVSS
MUL_3818|M.ulcerans_Agy99           AELVERYHDVVVERVGIREFVDDGTIDSDHSSPLLVSVFLDKDFSFVVSS
MLBr_01191|M.leprae_Br4923          SELVERYHDTVVQRCGIREFVDDGTIDPDHAYPLLVSVFLDKDFAFVVSS
MAV_1650|M.avium_104                SELVERYHDTVVARCGIREFVDDGAIDPDHASPLLVSVFLDKDFTFVVSS
MAB_1512|M.abscessus_ATCC_1997      AELVERYHDKVVANIGVREFVDDGAIDPDHASPLLVSVFLDKDFTFTVST
                                     ::*:**** ** . *:****.*.:**.**. ********:*** *.**:

Mflv_2532|M.gilvum_PYR-GCK          EADARAFVQFDPEHTVISPVPDSSDWTVTRKAGTEIRVPRKAKLSRTVGA
Mvan_4125|M.vanbaalenii_PYR-1       EADARAFVQFDPEHTLARPIPDSGDWEVIRKAGTEIRVPRKTKLSRTVGA
TH_1319|M.thermoresistible__bu      EADARAFVEFDPEHTVIRPVPDSTDWQVTRKAGTEIRVPRKTKLSRTVGA
MSMEG_4757|M.smegmatis_MC2_155      EADARAFVQFDPEHTVARPLPDSSDWEVTRKAGTEIRVPRKTKLSRTVGA
Rv2524c|M.tuberculosis_H37Rv        EADARAFVEFDPEHTVIRPVPDSTDWQVIRKAGTEIRVPRKTKLSRVVGG
Mb2553c|M.bovis_AF2122/97           EADARAFVEFDPEHTVIRPVPDSTDWQVIRKAGTEIRVPRKTKLSRVVGG
MMAR_3962|M.marinum_M               EADARAFADFDPEHTVIRPVPDSGDWQVIRKAGTEIRVPRKTTLSRVVGA
MUL_3818|M.ulcerans_Agy99           EADARAFADFDPEHTVIRPVPDSGDWQVIRKAGTEIRVPRKTTLSRVVGA
MLBr_01191|M.leprae_Br4923          EADARAFVEFDPEHTVIRPVPDSSDWQVIRKAGTEIRVPRKMKLSRVVGG
MAV_1650|M.avium_104                EADARAFVEFDPEHTIIRPVPDSSDWQVTRKAGTEIRVPRKTKLSRVVGG
MAB_1512|M.abscessus_ATCC_1997      EAEAREFVKWDPEHTVIQPLADGSDWQVTRKSGTEVRVPRKTKLSRTVGA
                                    **:** *..:*****:  *:.*. ** * **:***:***** .***.**.

Mflv_2532|M.gilvum_PYR-GCK          QIPTGFDPQVWGVTPDMANSIDRVALWNLVATVDAFLSAGFSPTELMRWV
Mvan_4125|M.vanbaalenii_PYR-1       QIPTGFDPTVWGISPDMATSVDRVALWNIVATVDAFLSSGFTPSELMRWV
TH_1319|M.thermoresistible__bu      QIPTGWDPTVWGISQDMANSIDRVALWNIVATVDAFLSAGFTPAELMRWV
MSMEG_4757|M.smegmatis_MC2_155      QIPTGFDPTVWGISPDMASSIDRVALWNIVATVDAFLSSGFTPTELMRWV
Rv2524c|M.tuberculosis_H37Rv        QIPTGFDPTVWGISADMAGSIDRLAVWNMVATVDAFLSSGFSPAEVMRYV
Mb2553c|M.bovis_AF2122/97           QIPTGFDPTVWGISADMAGSIDRLAVWNMVATVDAFLSSGFSPAEVMRYV
MMAR_3962|M.marinum_M               QLPTGFDPTVWGISQDMASSIDRVAVWNIVATVDAFLSAGFSPTEVMRYV
MUL_3818|M.ulcerans_Agy99           QLPTGFDPTVWGISQDMASSIDRVAVWNIVATVDAFLSAGFSPTEVMRYV
MLBr_01191|M.leprae_Br4923          QIPTGFDPTVWGISPDMVSSIDRVAVWSIVATVDAFLSAGFTPAEVMRYV
MAV_1650|M.avium_104                QLPTGFDPTVWGISPDMASSIDRVAVWNIVATVDAFLSAGFSPAEVMRYV
MAB_1512|M.abscessus_ATCC_1997      QIPTGFDPTVWGITPDMVSSIDRVALWNMVATVDAFLSAGFTPTELMRWV
                                    *:***:** ***:: **. *:**:*:*.:*********:**:*:*:**:*

Mflv_2532|M.gilvum_PYR-GCK          HPSLVASTQGTGMGGLTSMQTMFHGNLLDKNKPNDILQETLPNVVAAHVI
Mvan_4125|M.vanbaalenii_PYR-1       HPSLVASTQGTGMGGMTSMQTMFHGNLLGRSKPNDILQEVLPNVVAAHVM
TH_1319|M.thermoresistible__bu      HPTQVASTQGTGMGGMTSMQTMYHGNLLGRNKPNDILQEVLPNVVAAHVV
MSMEG_4757|M.smegmatis_MC2_155      HPSQVASTQGTGMGGMTSMQTMYHGNLLGRAKPNDILQEVLPNVVAAHVM
Rv2524c|M.tuberculosis_H37Rv        HPSLVANTQGTGMGGGTSMQTMYHGNLLGRNKPNDIFQEVLPNIIAAHVV
Mb2553c|M.bovis_AF2122/97           HPSLVANTQGTGMGGGTSMQTMYHGNLLGRNKPNDIFQEVLPNIIAAHVV
MMAR_3962|M.marinum_M               HPSLVANTMGTGMGGGTSMQTMYHGNLLGRNKPNDIFQEILPNIVAAHVV
MUL_3818|M.ulcerans_Agy99           HPSLVANTMGTGVGGGTSMQTMYHGNLLGRNKPNDIFQEILPNIVAAHVV
MLBr_01191|M.leprae_Br4923          HPSLVANTMGTGMGGGTSIQRLYHSSLLGRNKPNDIFQEILPNIVAAHVV
MAV_1650|M.avium_104                HPSLVANTMGTGMGGGTSMQTLYHGNLLGRNKPNDIFQEILPNIVAAHVV
MAB_1512|M.abscessus_ATCC_1997      HPSQVANTQGTGMGGMTSMQTMYHGNLLGRNKPNDILQEVLPNVVAAHVV
                                    **: **.* ***:** **:* ::*..**.: *****:** ***::****:

Mflv_2532|M.gilvum_PYR-GCK          QSYVGSYGSMIHPVGACATAAVSLEEGVDKIRLGKAELVVTGGYDDLTLE
Mvan_4125|M.vanbaalenii_PYR-1       QSYVGGYGAMVHPVGACATAAVSVEEGVDKIRLGKAELVVAGGFDDMTLE
TH_1319|M.thermoresistible__bu      QSYIGSYGAMIHPVAACATAAVSVEEGVDKIRLGKAELVVTGGFDDLTLE
MSMEG_4757|M.smegmatis_MC2_155      QSYVGGYGAMVHPVGACATAAVSVEEGVDKIKLGKADLVIAGGFDDLTLE
Rv2524c|M.tuberculosis_H37Rv        QSYVGSYGAMIHPVAACATAAVSVEEGVDKIRLGKAQLVVAGGLDDLTLE
Mb2553c|M.bovis_AF2122/97           QSYVGSYGAMIHPVAACATAAVSVEEGVDKIRLGKAQLVVAGGLDDLTLE
MMAR_3962|M.marinum_M               QSYIGSYGSMIHPVAACATAAVSVEEGVDKIRLGKAEMVVAGGIDDLTLE
MUL_3818|M.ulcerans_Agy99           QSYIGSYGSMIHPVAACATAAVSVEEGVDKIRLGKAEMVVAGGIDDLTLE
MLBr_01191|M.leprae_Br4923          QSYIGSYGSMIHPVAACATAAVSVEEGVDKIRLGKAELVVAGGIDDLTLE
MAV_1650|M.avium_104                QSYIGSYGAMIHPVAACATAAVSVEEGVDKIRLGKAEMVVAGGIDDLTLE
MAB_1512|M.abscessus_ATCC_1997      QSYVGSYGAMIHPVAACATAAVSVEEGVDKIRLGKAQLALAGGFDDLTLE
                                    ***:*.**:*:***.********:*******:****::.::** **:***

Mflv_2532|M.gilvum_PYR-GCK          AVIGFGDMAATADTEVMRAKGISDARFSRANDRRRLGFVEAQGGGTILLA
Mvan_4125|M.vanbaalenii_PYR-1       AIIGFGDMAATADTEMMRAKGISDSKFSRANDRRRLGFLEAEGGGTVLLA
TH_1319|M.thermoresistible__bu      AIIGFGDMAATAETAMMRAKGISDSKFSRANDRRRLGFVEAQGGGTILLA
MSMEG_4757|M.smegmatis_MC2_155      AIIGFGDMAATADTEMMRAKGISDSKFSRANDRRRLGFLEAQGGGTILLA
Rv2524c|M.tuberculosis_H37Rv        GIIGFGDMAATADTSMMCGRGIHDSKFSRPNDRRRLGFVEAQGGGTILLA
Mb2553c|M.bovis_AF2122/97           GIIGFGDMAATADTSMMRGRGIHDSKFSRPNDRRRLGFVEAQGGGTILLA
MMAR_3962|M.marinum_M               GIIGFGDMAATADTAMMRGRGIADSKFSRPNDRRRLGFVEAQGGGTILLA
MUL_3818|M.ulcerans_Agy99           GIIGFGDMAATADTAMMRGRGIADSKFSRPNDRRRLGFVEAQGGGTILLA
MLBr_01191|M.leprae_Br4923          GIIGFGDMAATADTAMMRGRGIHDSKFSRPNDRRRLGFVEAQGGGTILLA
MAV_1650|M.avium_104                GIIGFGDMAATADTGMMRGRGISDAKFSRPNDRRRLGFVEAQGGGTILLA
MAB_1512|M.abscessus_ATCC_1997      AIIGFGDMAATADTEMMRAKGIADKRFSRANDRRRLGFVEAQGGGSVLLA
                                    .:**********:* :* .:** * :***.********:**:***::***

Mflv_2532|M.gilvum_PYR-GCK          RGDLALRMGLPVLAVVAYAQSYADGVHTSIPAPGLGALGAGRGGRESVLA
Mvan_4125|M.vanbaalenii_PYR-1       RGDLALKMGLPVLAVVGYAQSFADGVHTSIPAPGLGALGAGRGGRDSVLA
TH_1319|M.thermoresistible__bu      RGDLALKMGLPVLAVVAYAQSFGDGVHTSIPAPGLGALGAGRGGRDSALA
MSMEG_4757|M.smegmatis_MC2_155      RGDLALKMGLPVLAVVGYAQSFADGVHTSIPAPGLGALGAARGGRESTLA
Rv2524c|M.tuberculosis_H37Rv        RGDLALRMGLPVLAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGKDSPLA
Mb2553c|M.bovis_AF2122/97           RGDLALRMGLPVLAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGKDSPLA
MMAR_3962|M.marinum_M               RGDLALKMGLPVLAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGRDSALA
MUL_3818|M.ulcerans_Agy99           RGDLALKMGLPVLAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGRDSALA
MLBr_01191|M.leprae_Br4923          RGDLALKMGLPVFAVVAFAQSFGDGVHTSIPAPGLGALGAGRGGKDSPLV
MAV_1650|M.avium_104                RGDLALKMGLPVLAVVAYAQSFADGVHTSIPAPGLGALGAGRGGKDSPLA
MAB_1512|M.abscessus_ATCC_1997      RGDLALKMGLPVLAVVAYAQSFGDGVHTSIPAPGLGALAAGRGGKDSDLA
                                    ******:*****:***.:***:.***************.*.***::* *.

Mflv_2532|M.gilvum_PYR-GCK          RSLNKLGVGADDIAVISKHDTSTLANDPNEQELHERLADSLGRSDGAPLF
Mvan_4125|M.vanbaalenii_PYR-1       RSLAKLGVGADDIAVISKHDTSTLANDPNETELHERLAASLGRSDGAPLF
TH_1319|M.thermoresistible__bu      RSLARLGVGPDDIAVVSKHDTSTLANDPNETELHERLADSLGRSPGNPMF
MSMEG_4757|M.smegmatis_MC2_155      RSLAQLGVGADDIAVISKHDTSTLANDPNETELHERIADSMGRAPGNPLF
Rv2524c|M.tuberculosis_H37Rv        RALAKLGVAADDVAVISKHDTSTLANDPNETELHERLADALGRSEGAPLF
Mb2553c|M.bovis_AF2122/97           RALAKLGVAADDVAVISKHDTSTLANDPNETELHERLADALGRSEGAPLF
MMAR_3962|M.marinum_M               RALAKLGVGADDIAIISKHDTSTLANDPNETELHERLADSLGRSEGAPLF
MUL_3818|M.ulcerans_Agy99           RALAKLGVGADDIAIISKHDTSTLANDPNETELHERLADSLGRSEGAPLF
MLBr_01191|M.leprae_Br4923          QSLAKLGVSADDIAVISKHDTSTLANDPNETELHERLADAMGRSAGAPLF
MAV_1650|M.avium_104                RALAKLGVGADDVAVISKHDTSTLANDPNETELHERLADSLGRSEGAPLF
MAB_1512|M.abscessus_ATCC_1997      RALNKLGVTADDIAVISKHDTSTLANDPNETELHERLAASLGRSDGAPLF
                                    ::* :*** .**:*::************** *****:* ::**: * *:*

Mflv_2532|M.gilvum_PYR-GCK          VVSQKSLTGHAKGGAAVFQTMGLCQILRDGVIPPNRSLDCVDEDLATSAH
Mvan_4125|M.vanbaalenii_PYR-1       VISQKSLTGHAKGGAAVFQMMGLCQVLRDGVIPPNRSLDCVDDELATSAH
TH_1319|M.thermoresistible__bu      VVSQKTLTGHAKGGAAVFQLMGLCQILRDGVVPPNRSLDCVDDELAGSEH
MSMEG_4757|M.smegmatis_MC2_155      IVSQKTLTGHAKGGAAVFQMMGLCQILRDGVIPPNRSLDCVDDELATSGH
Rv2524c|M.tuberculosis_H37Rv        VVSQKSLTGHAKGGAAVFQMMGLCQILRDGVIPPNRSLDCVDDELAGSAH
Mb2553c|M.bovis_AF2122/97           VVSQKSLTGHAKGGAAVFQMMGLCQILRDGVIPPNRSLDCVDDELAGSAH
MMAR_3962|M.marinum_M               VVSQKSMTGHAKGGAAVFQMMGLCQILRDGVIPPNRSLDCVDDELAGAAH
MUL_3818|M.ulcerans_Agy99           VVSQKSMTGHAKGGAAVFQMMGLCQILRDGVIPPNRSLDCVDDELAGAAH
MLBr_01191|M.leprae_Br4923          VVSQKSLTGHAKGGAAVFQMMGLCQMLRDGVIPPNRSLDCVDEELAGAAH
MAV_1650|M.avium_104                VVSQKSLTGHAKGGAAVFQMMGLCQMLRDGVIPPNRSLDCVDDELAGSAH
MAB_1512|M.abscessus_ATCC_1997      IISQKNLTGHAKGGAAVFQMLGLCQVLRDGVIPPNRSLDCVDDELSTSQH
                                    ::***.:************ :****:*****:**********::*: : *

Mflv_2532|M.gilvum_PYR-GCK          FVWPRETLRLGEKYPLKAGLITSLGFGHVSGLIALVHPQAFLATLTAEQR
Mvan_4125|M.vanbaalenii_PYR-1       FVWPRETLRLGEKYPLKAGLVTSLGFGHVSGLIALVHPQAFLATLTPEQR
TH_1319|M.thermoresistible__bu      FVWPRETLRLGEKFPLKAGLVTSLGFGHVSGLIALVHPQAFLAALSPEER
MSMEG_4757|M.smegmatis_MC2_155      FVWVREPLDLRGKFPLKAGLVTSLGFGHVSGLVALVHPEAFIAALDPSER
Rv2524c|M.tuberculosis_H37Rv        FVWVRDTLRLGGKFPLKAGMLTSLGFGHVSGLVALVHPQAFIASLDPAQR
Mb2553c|M.bovis_AF2122/97           FVWVRDTLRLGGKFPLKAGMLTSLGFGHVSGLVALVHPQAFIASLDPAQR
MMAR_3962|M.marinum_M               FVWVRDALRLGGKFPLKAGMLTSLGFGHVSGLVALVHPQAFIASLAPEQR
MUL_3818|M.ulcerans_Agy99           FVWVRDALRLGGKFPLKAGMLTSLGFGHVSGLVALVHPQAFIASLAPEQR
MLBr_01191|M.leprae_Br4923          FVWLRDTLRLGEKFPLKAGMLTSLGFGHVSGLVALVHPQAFIAALDPGQR
MAV_1650|M.avium_104                FVWVRETLRLGDKFPLKAGMVTSLGFGHVSGLVALVHPQAFLAALDPEQR
MAB_1512|M.abscessus_ATCC_1997      FVWLRESLPLKEKLPLKAGLVTSLGFGHVSGLVALVHPQAFIASLRPEDR
                                    *** *:.* *  * *****::***********:*****:**:*:* . :*

Mflv_2532|M.gilvum_PYR-GCK          ADYTALAQERTLAGQRRLVSAIAGGRPMYERPDGRRFDSDH--PEKTQEA
Mvan_4125|M.vanbaalenii_PYR-1       AAYTAQAQERVLAGQRRLASAIAGGRPMFERPADRRFDHDE--SEKAQEA
TH_1319|M.thermoresistible__bu      EAYTKRAEQRLLAGQRRLASAIAGGPPMYEKPSGRRFDQDV--PEKRQEA
MSMEG_4757|M.smegmatis_MC2_155      EDYRTRAEQRMLAGQRRLVSAIAGGRPMYEKPADRRFDHDV--PEKRQEA
Rv2524c|M.tuberculosis_H37Rv        ADYQRRADARLLAGQRRLASAIAGGAPMYQRPGDRRFDHHA--PERPQEA
Mb2553c|M.bovis_AF2122/97           ADYQRRADARLLAGQRRLASAIAGGAPMYQRPGDRRFDHHA--PERPQEA
MMAR_3962|M.marinum_M               ADYQRRADTRLLAGQRRLASAMAGGEPMYQRPPDRRFDHDT--AEKPQEA
MUL_3818|M.ulcerans_Agy99           ADYERRADTRLLAGQRRLASAMAGGEPMYQRPPDRRFDHDT--AEKPQEA
MLBr_01191|M.leprae_Br4923          DDYQRRANVRLLAGQRRLASAIAGGAPMYERPPDRRFDHHV--PEKLQEA
MAV_1650|M.avium_104                ADYQQRANARLLAGQRRLVSAIAGGAPMYQRPPDRRFDHDV--PEKRQEA
MAB_1512|M.abscessus_ATCC_1997      ADYETRSRERVLAGQRRLASAMAGGRPMYERPDGRRFDHDHDESEKRQEA
                                      *   :  * *******.**:*** **:::* .**** .   .*: ***

Mflv_2532|M.gilvum_PYR-GCK          GMLLDVASRLDENGVYRR------
Mvan_4125|M.vanbaalenii_PYR-1       AMLLDAASRLGEDGVYRR------
TH_1319|M.thermoresistible__bu      AMLLSTDARLGEDGVYVLGGDVGA
MSMEG_4757|M.smegmatis_MC2_155      AMLLSTDARLGENDQYVL------
Rv2524c|M.tuberculosis_H37Rv        SMLLNPAARLGDGEAYIG------
Mb2553c|M.bovis_AF2122/97           SMLLNPAARLGDGEAYIG------
MMAR_3962|M.marinum_M               AMLLNPAARLGDGEAYIG------
MUL_3818|M.ulcerans_Agy99           AMLLNPAARLGDGEAYIG------
MLBr_01191|M.leprae_Br4923          AMLLNPAARLGDGDAYIG------
MAV_1650|M.avium_104                AMLLDPASRLGDGDAYQVSAG---
MAB_1512|M.abscessus_ATCC_1997      SMLLDPGARLSEDEVYHR------
                                    .***.  :**.:.  *