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M. tuberculosis H37Rv Rv0189c (ilvD)

annotation: dihydroxy-acid dehydratase
coordinates: 219996 - 221723
length: 575

PQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNEITPCNLSLDRL
ANAVKEGVFSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVEVVMQAERLDGSVLLAGCDKSL
PGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTIIDAFEAVGACSRGLMSRADVDAIERAICPGE
GACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAI
AVVMAFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMSDVDHIGGVPVVMKALL
DAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGFDSDV
FEGTARVFDGERAALDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFS
GGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFASRQQDFSPPPPRYTTGVLSKY
VKLVSSAAVGAVCG*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv0189c ilvD - 100% (575) dihydroxy-acid dehydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0195c ilvD 0.0 100.00% (575) dihydroxy-acid dehydratase
M. gilvum PYR-GCK Mflv_0486 - 0.0 85.34% (566) dihydroxy-acid dehydratase
M. leprae Br4923 MLBr_02608 ilvD 0.0 90.00% (560) dihydroxy-acid dehydratase
M. abscessus ATCC 19977 MAB_4545 - 0.0 85.19% (567) dihydroxy-acid dehydratase
M. marinum M MMAR_0432 ilvD 0.0 91.62% (561) dihydroxy-acid dehydratase IlvD
M. avium 104 MAV_4989 ilvD 0.0 90.96% (575) dihydroxy-acid dehydratase
M. smegmatis MC2 155 MSMEG_0229 ilvD 0.0 85.15% (559) dihydroxy-acid dehydratase
M. thermoresistible (build 8) TH_0983 ilvD 0.0 90.34% (559) PROBABLE DIHYDROXY-ACID DEHYDRATASE ILVD (DAD)
M. ulcerans Agy99 MUL_1082 ilvD 0.0 91.44% (561) dihydroxy-acid dehydratase
M. vanbaalenii PYR-1 Mvan_0173 - 0.0 88.55% (559) dihydroxy-acid dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


Rv0189c|M.tuberculosis_H37Rv        ---------------MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARG
Mb0195c|M.bovis_AF2122/97           ---------------MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARG
MLBr_02608|M.leprae_Br4923          --------------------------MMPPDIKPRSRDVTDGLEKAAARG
MMAR_0432|M.marinum_M               --------------------------MPEADIKPRSRDVTDGLEKAAARG
MUL_1082|M.ulcerans_Agy99           --------------------------MPEADIKPRSRDVTDGLEKAAARG
MAV_4989|M.avium_104                ---------------MPTTDSARAADIKQPDIKPRSRDVTDGLEKAAARG
TH_0983|M.thermoresistible__bu      ------------------------MAQNQPDIKPRSRDVTDGLEKAAARG
Mvan_0173|M.vanbaalenii_PYR-1       -------------------------MPSSPDIKPRSRDVTDGLEKAAARG
Mflv_0486|M.gilvum_PYR-GCK          MWPMNRRAHNHPMPSDSRSHSLRASGSS-VDIKPRSRDVTDGLERTAARG
MAB_4545|M.abscessus_ATCC_1997      ------------MSAPHKPDSLRASGSSQPDIKPRSRDVTDGLEKTAARG
MSMEG_0229|M.smegmatis_MC2_155      ------------MPSDDKS-------TETPDIKPRSRDVTDGLEKAAARG
                                                                  **************::****

Rv0189c|M.tuberculosis_H37Rv        MLRAVGMDDEDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGVFSAGGY
Mb0195c|M.bovis_AF2122/97           MLRAVGMDDEDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGVFSAGGY
MLBr_02608|M.leprae_Br4923          MLRAVGMNDDDFAKAQIGVASSWNEITPCNLSLDRLAKAVKEGVFSAGGY
MMAR_0432|M.marinum_M               MLRAVGMVDEDFAKAQIGVASSWNEITPCNLSLDRLAKSVKEGVFAAGGY
MUL_1082|M.ulcerans_Agy99           MLRAVGMVDEDFAKAQIGVASSWNEITPCNLSLDRLAKSVKEGVFAAGGY
MAV_4989|M.avium_104                MLRAVGMGDEDFAKPQIGVASSWNEITPCNLSLDRLAKAVKEGVFAAGGY
TH_0983|M.thermoresistible__bu      MLRAVGMGDEDFAKPQIGVASSWNEITPCNLSLDRLAKAVKDGVHAAGGY
Mvan_0173|M.vanbaalenii_PYR-1       MLRAVGMGDEDFAKPQIGVGSSWNEITPCNLSLDRLAKAVKEGVFEAGGF
Mflv_0486|M.gilvum_PYR-GCK          MLRAVGMTDDDWVKPQIGVGSSWNEITPCNMSLQRLAQAVKGGVHEAGGY
MAB_4545|M.abscessus_ATCC_1997      MLRAVGMGDDDWVKPQIGVGSSWNEITPCNMSLQRLAHSVKDGVHEAGGY
MSMEG_0229|M.smegmatis_MC2_155      MLRAVGMGDADWAKPQIGVGSSWNEITPCNMSLQRLAKSVKDGVHEAGGY
                                    ******* * *:.*.****.**********:**:***::** **. ***:

Rv0189c|M.tuberculosis_H37Rv        PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVEVVMQAERLDGSVLLA
Mb0195c|M.bovis_AF2122/97           PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVEVVMQAERLDGSVLLA
MLBr_02608|M.leprae_Br4923          PLEFGTISVSDGISMGHQGMHFSLVSREVIADSVETVMQAERLDGSVLLA
MMAR_0432|M.marinum_M               PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLA
MUL_1082|M.ulcerans_Agy99           PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLA
MAV_4989|M.avium_104                PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLA
TH_0983|M.thermoresistible__bu      PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLA
Mvan_0173|M.vanbaalenii_PYR-1       PMEFGTISVSDGISMGHEGMHFSLVSREIIADSVETVMQAERLDGSVLLA
Mflv_0486|M.gilvum_PYR-GCK          PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVVQAERLDGTVLLA
MAB_4545|M.abscessus_ATCC_1997      PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLA
MSMEG_0229|M.smegmatis_MC2_155      PLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVVQAERLDGTVLLA
                                    *:***************:**********:******.*:*******:****

Rv0189c|M.tuberculosis_H37Rv        GCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTIIDAFE
Mb0195c|M.bovis_AF2122/97           GCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTIIDAFE
MLBr_02608|M.leprae_Br4923          GCDKSLPGMLMAAARLDLASVFLYAGSILPGRTKLSDGTEHEVTLIDAFE
MMAR_0432|M.marinum_M               GCDKSLPGMLMAAARLDLASVFLYAGSILPGVAKLSDGSEREVTIIDAFE
MUL_1082|M.ulcerans_Agy99           GCDKSLPGMLMAAARLDLASVFLYAGSILPGVAKLSDGSEREVTIIDAFE
MAV_4989|M.avium_104                GCDKSLPGMLMAAARLDLASVFLYAGSILPGVAKLSDGSEREVTIIDAFE
TH_0983|M.thermoresistible__bu      GCDKSLPGMLMAAARLDLAAVFLYAGSILPGIAKLSDGTEREVTIIDAFE
Mvan_0173|M.vanbaalenii_PYR-1       GCDKSLPGMLMAAARLDLASVFLYAGSILPGRVKLSDGSEKDVTIIDAFE
Mflv_0486|M.gilvum_PYR-GCK          GCDKSIPGMLMAAARLDLASVFFYNGSIMPGVAKLTDGSEKEVTIIDAFE
MAB_4545|M.abscessus_ATCC_1997      GCDKSIPGMLMAAARLDLASVFLYNGSIMPGKAKLTDGTEKEVTIIDAFE
MSMEG_0229|M.smegmatis_MC2_155      GCDKSIPGMLMAAARLDLASVFFYNGSIMPGVAKLTDGTEKEVTIIDAFE
                                    *****:*************:**:* ***:** .**:**:*::**:*****

Rv0189c|M.tuberculosis_H37Rv        AVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
Mb0195c|M.bovis_AF2122/97           AVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
MLBr_02608|M.leprae_Br4923          AVGACSRGLMPRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
MMAR_0432|M.marinum_M               AVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
MUL_1082|M.ulcerans_Agy99           AVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
MAV_4989|M.avium_104                AVGACARGLMPREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
TH_0983|M.thermoresistible__bu      AVGACARGLMPREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
Mvan_0173|M.vanbaalenii_PYR-1       AVGACARGLMPREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLP
Mflv_0486|M.gilvum_PYR-GCK          AVGACARGLMSREDVDIIERAICPGEGACGGMYTANTMASAAEALGMSLP
MAB_4545|M.abscessus_ATCC_1997      AVGACARGLMSREDVDIIERAICPGEGACGGMYTANTMASAAEALGMSLP
MSMEG_0229|M.smegmatis_MC2_155      AVGACVRGLMSREDVDIIERAICPGEGACGGMYTANTMASAAEALGLSLP
                                    ***** ****.* *** *****************************:***

Rv0189c|M.tuberculosis_H37Rv        GSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVM
Mb0195c|M.bovis_AF2122/97           GSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVM
MLBr_02608|M.leprae_Br4923          GSAAPPATDRRRDGFARRSGQAVIELLRRGITARDILTKEAFENAIAVVM
MMAR_0432|M.marinum_M               GSAAPPATDRRRDGFARQSGQAVIELLRQGITARDIMTREAFENAIAVVM
MUL_1082|M.ulcerans_Agy99           GSAAPPATDRRRDGFARQSGQAVIELLRQGITARDIMTREAFENAIAVVM
MAV_4989|M.avium_104                GSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVM
TH_0983|M.thermoresistible__bu      GSAAPPATDRRRDGFARKSGQAVVELLRRGITARDILTKEAFENAIAVVM
Mvan_0173|M.vanbaalenii_PYR-1       GSAAPPATDRRRDGFARKSGMAVVELLRRGITARDILTKEAFENAIAVVM
Mflv_0486|M.gilvum_PYR-GCK          GSASPVAIDKRRDDFARRSGEAVVEMLRRGITARDILTKEAFENAIAVVM
MAB_4545|M.abscessus_ATCC_1997      GSASPVAIDKRREEYARKSGEAVVEMLRRGITARDILTKEAFENAIAVVM
MSMEG_0229|M.smegmatis_MC2_155      GSASPVAIDKRRDEFARRSGEAVVDMLRRGITARDILTKEAFENAIAVVM
                                    ***:* * *:**: :**:** **:::**:*******:*:***********

Rv0189c|M.tuberculosis_H37Rv        AFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMS
Mb0195c|M.bovis_AF2122/97           AFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMS
MLBr_02608|M.leprae_Br4923          AFGGSTNAILHLLAIAHEADVTLSLEDFSRIGFKVPHIADVKPFGRHVMF
MMAR_0432|M.marinum_M               AFGGSTNAVLHLLAIAHEANVELTLDDFSRIGSKVPHLADVKPFGRHVMS
MUL_1082|M.ulcerans_Agy99           AFGGSTNAVLHLLAIAHEANVELTLDDFSRIGSKVPHLADVKPFGRHVMS
MAV_4989|M.avium_104                AFGGSTNAVLHLLAIAHEADVALSLDDFSRIGSKVPHLADVKPFGRHVMT
TH_0983|M.thermoresistible__bu      AFGGSTNAVLHLLAIAHEANVKLTLEDFTRIGNKVPHLADVKPFGAHVMF
Mvan_0173|M.vanbaalenii_PYR-1       AFGGSTNAVLHLLAIAYEANVKLTLEDFTRVGAKVPHLADVKPFGAYVMN
Mflv_0486|M.gilvum_PYR-GCK          AFGGSTNAVLHLLAIAWEAQVELTLADFTRIGQKVPHLADVKPFGAYVMK
MAB_4545|M.abscessus_ATCC_1997      AFGGSTNAVLHLLAIAKEAEVELSLADFTRIGNKVPHLADVKPFGRHVMK
MSMEG_0229|M.smegmatis_MC2_155      AFGGSTNAVLHLLAIAREAEVELTLDDFTRVGSKVPHLADVKPFGRHVMK
                                    ********:******* **:* *:* **:*:*  ***:******* :** 

Rv0189c|M.tuberculosis_H37Rv        DVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVL
Mb0195c|M.bovis_AF2122/97           DVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVL
MLBr_02608|M.leprae_Br4923          DVDHIGGVPVVMKALLDAGLLHGDCLTVTGQTMAENLASIAPPDPDGQVI
MMAR_0432|M.marinum_M               HVDHIGGVPVVMKTLLDAGLLHGDCLTVTGRTVAENLEAIAPPDPDGKVL
MUL_1082|M.ulcerans_Agy99           HVDHIGGVPVVMKTLLDAGLLHGDCLTVTGRTVAENLEAIAPPDPDGKVL
MAV_4989|M.avium_104                DVDHIGGVPVMMKALLDAGLLNGDCLTVTGATVAQNLAAIAPPDPDGKVL
TH_0983|M.thermoresistible__bu      DVDHIGGVPVIMKTLLDAGLLHGDCLTVTGKTMAENLAHIAPPDPDGKVL
Mvan_0173|M.vanbaalenii_PYR-1       DVDRIGGVPVVMKALLDAGLLHGDCLTVTGKTMAENLAHIAPPDPDGKVL
Mflv_0486|M.gilvum_PYR-GCK          HVDEIGGVPVVMRALLDAGLLHGDCLTVTGQTMAENLAHIEPPDPDGKVL
MAB_4545|M.abscessus_ATCC_1997      DVDEIGGVPVVMRALLDAGLLHGDCLTVTGKTMAENLAHIAPPDPDGKVL
MSMEG_0229|M.smegmatis_MC2_155      HVDEIGGVPVVMRALLDAGLLNGECLTVTGKTMAENLAHIAPPDPDGKVL
                                    .**.******:*::*******:*:****** *:*:**  * ******:*:

Rv0189c|M.tuberculosis_H37Rv        RALANPIHPSGGITILHGSLAPEGAVVKTAGFDSDVFEGTARVFDGERAA
Mb0195c|M.bovis_AF2122/97           RALANPIHPSGGITILHGSLAPEGAVVKTAGFDSDVFEGTARVFDGERAA
MLBr_02608|M.leprae_Br4923          RTLHNPIHPTGGITILRGSLAPDGAVVKTAGLDSDVFEGTARVFDGERAA
MMAR_0432|M.marinum_M               RALNNPIHATGGITILRGSLAPEGAVVKTAGLDTDVFEGTARVFDGERAA
MUL_1082|M.ulcerans_Agy99           RALINPIHATGGITILRGSLAPEGAVVKTAGLDTDVFEGTARVFDGERAA
MAV_4989|M.avium_104                RALSDPLHPTGGITILRGSLAPEGAVVKSAGFDSDVFEGTARVFDGERAA
TH_0983|M.thermoresistible__bu      RALSNPIHPTGGITILHGSLAPEGAVVKSAGFDTSVFEGTARVFDRERAA
Mvan_0173|M.vanbaalenii_PYR-1       RALSRPIHPTGGITILHGSLAPEGAVVKSAGFDSDVFEGTARVFERERAA
Mflv_0486|M.gilvum_PYR-GCK          RAMNNPIHPTGGITILHGSLAPEGAVVKSAGFDSDVFEGTARVFERERAA
MAB_4545|M.abscessus_ATCC_1997      RAMNDPIHPTGGITILHGSLAPEGAVVKSAGFESDVFEGTARVFERERAA
MSMEG_0229|M.smegmatis_MC2_155      RAMNNPIHPTGGITILHGSLAPEGAVVKSAGFDSDVFEGTARVFDRERAA
                                    *::  *:*.:******:*****:*****:**:::.*********: ****

Rv0189c|M.tuberculosis_H37Rv        LDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
Mb0195c|M.bovis_AF2122/97           LDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
MLBr_02608|M.leprae_Br4923          LDALKDGTIAKGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
MMAR_0432|M.marinum_M               LDALEDGTITHGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
MUL_1082|M.ulcerans_Agy99           LDALEDGTITHGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
MAV_4989|M.avium_104                LDALEDGTITKGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
TH_0983|M.thermoresistible__bu      MDALEDGTIQAGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLL
Mvan_0173|M.vanbaalenii_PYR-1       LDALEDGTITHGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLM
Mflv_0486|M.gilvum_PYR-GCK          LDALEDGTITHGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLM
MAB_4545|M.abscessus_ATCC_1997      LDALEDGTITHGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLM
MSMEG_0229|M.smegmatis_MC2_155      MDALEDGTIQAGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLM
                                    :***:****  **.***********************************:

Rv0189c|M.tuberculosis_H37Rv        TDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLAD
Mb0195c|M.bovis_AF2122/97           TDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLAD
MLBr_02608|M.leprae_Br4923          TDGRFSGGTTGFCVGHIAPEAVEAGPIAFLRDGDRVLLDVVGCSLDVLVD
MMAR_0432|M.marinum_M               TDGRFSGGTTGFCVGHIAPEAVDAGPIAFVRDGDRIRLDVAGRTLDVLTD
MUL_1082|M.ulcerans_Agy99           TDGRFSGGTTGFCVGHIAPEAVDAGPIAFVRDGDRIRLDVAGRTLDVLTD
MAV_4989|M.avium_104                TDGRFSGGTTGLCVGHIAPEAVDAGPIAFLRDGDRIRLDVANRVLDVLVD
TH_0983|M.thermoresistible__bu      TDGRFSGGTTGLCVGHVAPEAVDGGPIAFLRDGDRIRLDVAKGTLDVLVD
Mvan_0173|M.vanbaalenii_PYR-1       TDGRFSGGTTGLCVGHIAPEAVDGGPIAFIKDGDKIRLDVAKGTLDVVVD
Mflv_0486|M.gilvum_PYR-GCK          TDGRFSGGTTGLCVGHIAPEAVDGGPIAFVRDGDRIRLDVANGTLDILVD
MAB_4545|M.abscessus_ATCC_1997      TDGRFSGGTTGLCVGHIAPEAVDGGPIAFVRDGDRIRLDVANGKLDLLVD
MSMEG_0229|M.smegmatis_MC2_155      TDGRFSGGTTGLCVGHIAPEAVDGGPIAFVRDGDRIRLDVAKGTLDVLVD
                                    ***********:****:*****:.****::::**:: ***.   **::.*

Rv0189c|M.tuberculosis_H37Rv        PAEFASRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG
Mb0195c|M.bovis_AF2122/97           PAEFASRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG
MLBr_02608|M.leprae_Br4923          PVEFSSRKKDFIPPAPRYTTGVLAKYVKLVSSATVGAVCG
MMAR_0432|M.marinum_M               PAEFAARQQNFTPPAPRYKTGVLAKYVKLVGSAAIGAVCG
MUL_1082|M.ulcerans_Agy99           PPEFAARQQNFTPPAPRYKTGVLAKYVKLVGSAAIGAVCG
MAV_4989|M.avium_104                PAEFDSRRTAFTPPPPRYKTGVLAKYVKLVGSAAIGAVCG
TH_0983|M.thermoresistible__bu      PAEFEARKKDWEPLPPRYTTGVLAKYTKLVGSAATGAVCT
Mvan_0173|M.vanbaalenii_PYR-1       KDEFEARKVGFEPLPPVYTTGVLAKYTKLVGSAATGAVCT
Mflv_0486|M.gilvum_PYR-GCK          EAEFESRKAGFEPLPPVYTTGVLAKYTKLVGSAAVGAVCS
MAB_4545|M.abscessus_ATCC_1997      EAEIAERRKGFEPLPPRYKTGVLAKYTKLVQSAAVGAVCG
MSMEG_0229|M.smegmatis_MC2_155      EEEFEARKAGFEPLPPRYKTGVLAKYTKLVQSAAVGAVCT
                                      *:  *:  : * .* *.****:**.*** **: ****

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv0189c	ilvD	-	100% (575)	dihydroxy-acid dehydratase