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VNSLALCHRFRVIARRALCALLGASLLFAFVAIDVGADPAADALAELTEQSRLAEQTTEQIHTAQIDLDE RLAAQQVAEKKAASDRVRVDAASADLAKYQAAVDKLAAAAYMGGRTDTLAAALTATSPQELIDQLAIQKT VASELTVQMAAFRSASARAATAADQSAMSAAQARGAADEAAAVRTDLEAKQRRMQEQIAVVQARYEALTT GQRAILADPGPPPPPLPPSSPANDPSIVAMPGPAVGGSPGGATAVVQAALTRVGSPYSWGATGPDAFDCS GLIKWAFLQNGKSLPRSSQALAQGGQPVATSDLQPGDIVTFYDDISHAGIYIGEGMMVHASTYGTPVKVA PISSAPIHNVRRY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0888 | - | - | 100% (363) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_2808 | - | e-116 | 65.17% (333) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_2959 | - | e-110 | 55.80% (371) | NLP/P60 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2213c | - | 1e-105 | 54.13% (375) | hypothetical protein Mb2213c |
| M. tuberculosis H37Rv | Rv2190c | - | 1e-105 | 54.13% (375) | hypothetical protein Rv2190c |
| M. leprae Br4923 | MLBr_00885 | - | 1e-100 | 51.92% (364) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1974 | - | 9e-93 | 51.79% (363) | hypothetical protein MAB_1974 |
| M. marinum M | MMAR_3234 | - | 1e-102 | 52.66% (376) | hypothetical protein MMAR_3234 |
| M. avium 104 | MAV_2304 | - | 3e-99 | 55.52% (344) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 1e-110 | 56.18% (372) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_3014 | - | 1e-111 | 58.02% (374) | PUTATIVE NLP/P60 family protein |
| M. ulcerans Agy99 | MUL_3545 | - | 8e-98 | 51.06% (378) | hypothetical protein MUL_3545 |
| M. vanbaalenii PYR-1 | Mvan_3713 | - | 1e-117 | 65.47% (333) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0888|M.gilvum_PYR-GCK ------MNSLALCHRFRVIARRALCALLGASLLFAFV-AIDVGADPAADA
Mvan_3713|M.vanbaalenii_PYR-1 -------------------MAIVLALTLGNSAGIG-------WADPAADA
Mb2213c|M.bovis_AF2122/97 ------MRLDQRWLIARVIMRSAIGFFASFTVSSGVL-AANVLADPADDA
Rv2190c|M.tuberculosis_H37Rv ------MRLDQRWLIARVIMRSAIGFFASFTVSSGVL-AANVLADPADDA
MMAR_3234|M.marinum_M ------MRLDCRQLTARVIRRSAIGSLASFTALSGFV-AAGAMADPAEDA
MUL_3545|M.ulcerans_Agy99 ------MRLDCRQLTARVIRRSAIGSLASFTALSGFV-AAGAMADQAEDA
MAV_2304|M.avium_104 --------------------------------------------------
MLBr_00885|M.leprae_Br4923 ------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFF-VATAMADPAEDA
MSMEG_4256|M.smegmatis_MC2_155 ------MRHARAHRPTSRFKRPIAGAIASLALGAGLL-AGSVQADPADDA
TH_3014|M.thermoresistible__bu ------LRIDRAHRIIRSVHRPLIALIAGLTLLATGI-AAPGHADPADDA
MAB_1974|M.abscessus_ATCC_1997 MSVGRLLRNHSDRLTPSPLRRAMLAVTAAALVGGVFTGAQTATADPNNDA
Mflv_0888|M.gilvum_PYR-GCK LAELTEQSRLAEQTTEQIHTAQIDLDERLAAQQVAEKKAASDRVRVDAAS
Mvan_3713|M.vanbaalenii_PYR-1 LARLTELSREAEQTTEAVYSAELDLEAKLAAQRRAEDRQRAELEAMTAAR
Mb2213c|M.bovis_AF2122/97 LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
Rv2190c|M.tuberculosis_H37Rv LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
MMAR_3234|M.marinum_M LAKLNELSRQAEQTTEAMHSAELDLGAKLAAQQAAENKLTDDQAALDAAK
MUL_3545|M.ulcerans_Agy99 LAKLNELSRQAEQTTEAMHSAELELGAKLAAQQAAENKLTDDQAALDATK
MAV_2304|M.avium_104 MAKLNELSRQAEQTTEAMHSAQLDLNEKLAAQRAAEKKHDDDQAAVDAAK
MLBr_00885|M.leprae_Br4923 LAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKKYTDDQAALADAQ
MSMEG_4256|M.smegmatis_MC2_155 LAKLNELSRQAEQTTEAMHSAQLDLDNKLAAQQAAEKKHSEDAAAAEQAR
TH_3014|M.thermoresistible__bu LAKLQELSRQAEQTTEAMHSARLDLEEKLAAQRAAEEKAAADAAAADAAT
MAB_1974|M.abscessus_ATCC_1997 VKKLNELSRQAEATSEAANTAKIDLDAKLAAQRDAEKTVLADEAVAKAAR
: .* * ** ** *:* :*.::* :****: *:. : :
Mflv_0888|M.gilvum_PYR-GCK ADLAKYQAAVDKLAAAAYMGGRTDTLAAALTATSPQELIDQLAIQKTVAS
Mvan_3713|M.vanbaalenii_PYR-1 ADLGEYQAAVNQVAAASYMGGSTSTISAALTAESPQRLLDELSSSRVMAT
Mb2213c|M.bovis_AF2122/97 ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
Rv2190c|M.tuberculosis_H37Rv ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
MMAR_3234|M.marinum_M GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMAH
MUL_3545|M.ulcerans_Agy99 GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMVH
MAV_2304|M.avium_104 AHLASYQNAVNNLAAATYMGGRVDGMEAILTAGSPQGLIDKLAVQRLMAT
MLBr_00885|M.leprae_Br4923 VRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQLINKLALQRVLGV
MSMEG_4256|M.smegmatis_MC2_155 AQLATFQASVNRVAAAQYMGGRTSGVDAILTADSPQQLIDQLAVQRVMAT
TH_3014|M.thermoresistible__bu AQLANYQTAVDKLAASQYMGGRTDGFNAILTARSPQQLIDQLAVQRVMAT
MAB_1974|M.abscessus_ATCC_1997 MAVSTYQVDVNKAMVAAYMGGTTSGYGAVLTSNSPQNLIDQLSVQRTVGG
:. :* *:. .: **.* : **: *** *:: *: .: :
Mflv_0888|M.gilvum_PYR-GCK ELTVQMAAFRSASARAATAADQSAMSAAQARGAADEAAAVRTDLEAKQRR
Mvan_3713|M.vanbaalenii_PYR-1 QMSDRIKAFRAASTRADDAARAAQSSALAARTAAEQASAVRASLQSKQSR
Mb2213c|M.bovis_AF2122/97 QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
Rv2190c|M.tuberculosis_H37Rv QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
MMAR_3234|M.marinum_M QMATQMSGFRTAREQAAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
MUL_3545|M.ulcerans_Agy99 QMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
MAV_2304|M.avium_104 QMASQMKSYRIAGEQAAKAERESAKSAADAKSAAEQAAAVRASLQSKQSQ
MLBr_00885|M.leprae_Br4923 QMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAAVVRAGLQSKQSK
MSMEG_4256|M.smegmatis_MC2_155 EMATQMQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQSQ
TH_3014|M.thermoresistible__bu EMSEQMHRFRLAQEEAAKAAEASAKSAAEARTAAEQAAAVRAELQAKQSE
MAB_1974|M.abscessus_ATCC_1997 EMRSRMDSYRAAQTSADEAEQRSRDAAEAARVAAEQAKNVRASLQAKQSQ
:: :: :: . : * : :* *: **::* **: *: ** .
Mflv_0888|M.gilvum_PYR-GCK MQEQIAVVQARYEALTTGQRAILADPGPPPPPLPPSSP------------
Mvan_3713|M.vanbaalenii_PYR-1 LRTQIAEVEALYRALTPDQRAALADPGP-VPPAPPVPP------------
Mb2213c|M.bovis_AF2122/97 LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
Rv2190c|M.tuberculosis_H37Rv LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
MMAR_3234|M.marinum_M LQVQIAVVKSQYLALTPDQRTALADPGQVPAGLPGAPG-PAPEGTPPGGP
MUL_3545|M.ulcerans_Agy99 LQVQIAVVKSQYLALTPDQRTALVDPGQVPAGLPGAPG-PAPEGTPPGGP
MAV_2304|M.avium_104 LQVQIAVVKSQYMSLTADQRTALANPGPAVPAAATAPGAPAPEAAPPG-T
MLBr_00885|M.leprae_Br4923 LQLQIAVVKSHYLSLSPRQRTTLAEPGPVPAVAT-LPG-----AASAGVS
MSMEG_4256|M.smegmatis_MC2_155 LQVQIAIVKSQYEALTPQQREALATAPPPPAAPPAPAP-----DALPPAN
TH_3014|M.thermoresistible__bu LQQQIEVVKAQYEALTPDQREALAAMPP---VPPGTPT-----GELPGQH
MAB_1974|M.abscessus_ATCC_1997 LQVQIAVVKSQYNTLSPGQRAQLAAPAPVPPPPAAEPG------------
:: ** *:: * :*:. :* *. . .
Mflv_0888|M.gilvum_PYR-GCK ----------ANDPSI-VAMPG--PAVGGSPGG---ATAVVQAALTRVGS
Mvan_3713|M.vanbaalenii_PYR-1 ----------AANPAI-MAMPEAIPPVGPGPSSSPEGAAVVQAALTRVGA
Mb2213c|M.bovis_AF2122/97 PPGDGPAPGVAPPP---GGMPGLPFVQPDGAGG--DRTAVVQAALTQVGA
Rv2190c|M.tuberculosis_H37Rv PPGDGPAPGVAPPP---GGMPGLPFVQPDGAGG--DRTAVVQAALTQVGA
MMAR_3234|M.marinum_M PPAGAPVPGEAPPP---GGVSAMPFTPPDGAGG--DRAAVVQAALTQVGT
MUL_3545|M.ulcerans_Agy99 PPAGAPVPGEAPPPGA-GGVSAMPFTPPDGAGG--DRAAVVQAALTQVGT
MAV_2304|M.avium_104 PPG-GPGPGEAPPP---GGAPGMAPGGGGVGGG--DRATVVQAALTQVGS
MLBr_00885|M.leprae_Br4923 PPP------DAAPP---GGLLGVAP-APFAGGG--DRAAVVQAALTQIGS
MSMEG_4256|M.smegmatis_MC2_155 DPGVLAAPPEGIPP---GDIAPPDAAIPGGPSP--VSNTVIQAALSRIGS
TH_3014|M.thermoresistible__bu DTEVLAAP--GIPP---GDLAP-EAAVPGGPSN--DRATVVQAALSRIGS
MAB_1974|M.abscessus_ATCC_1997 ------EAGDAPEPLMQAAAAAPAPEAAIGGGGSPAGAGAVAAALTRIGA
. * . .: ***:::*:
Mflv_0888|M.gilvum_PYR-GCK PYSWGATGPDAFDCSGLIKWAFLQ-NGKSLPRSSQALAQGGQPVATSDLQ
Mvan_3713|M.vanbaalenii_PYR-1 PYSWGATGPDAFDCSGLIKWAFLQ-NGKSLPRSSQALAAGGQPVATTEVQ
Mb2213c|M.bovis_AF2122/97 PYAWGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQ
Rv2190c|M.tuberculosis_H37Rv PYAWGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQ
MMAR_3234|M.marinum_M PYAWGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVSLSDLQ
MUL_3545|M.ulcerans_Agy99 PYAWGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHEGQPVSLSDLQ
MAV_2304|M.avium_104 PYVWGGAAPGGFDCSGLVMWAFQQ-AGISLPHSSQALAHGGQPVSLSDLQ
MLBr_00885|M.leprae_Br4923 PYAWGGAAPGGFDCSGLVMWAYQQ-AGIALPHSSQALARGGQPVSLSELQ
MSMEG_4256|M.smegmatis_MC2_155 PYSWGGSGPNAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMDNIQ
TH_3014|M.thermoresistible__bu PYSWGGSGPNAFDCSGLVMWAFRQGAGINLPHSSQALARGGQPVSMADIQ
MAB_1974|M.abscessus_ATCC_1997 PYSWGGSGPNAFDCSGLVMWAYGQ-QGVSLPHSSQALARGGTPVSLSELQ
** **.:.*..******: *:: * * **:****** * **: ::*
Mflv_0888|M.gilvum_PYR-GCK PGDIVTFYDDISHAGIYIGEGMMVHASTYGTPVKVAPISS-APIHNVRRY
Mvan_3713|M.vanbaalenii_PYR-1 PGDIVTFYSDASHAGIYIGDGNMVHASTYGTPVKVAPISS-APIYNVRRY
Mb2213c|M.bovis_AF2122/97 PGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
Rv2190c|M.tuberculosis_H37Rv PGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
MMAR_3234|M.marinum_M PGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
MUL_3545|M.ulcerans_Agy99 PGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
MAV_2304|M.avium_104 PGDVLTFYSDASHAGIYIGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MLBr_00885|M.leprae_Br4923 PGDVLTFYSDASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MSMEG_4256|M.smegmatis_MC2_155 PGDLVTYYSDASHVGIYIGDGMMVHASTYGSPVRVAPVNN-APIYNVRRY
TH_3014|M.thermoresistible__bu PGDVVTYYSDASHAAIYIGNGMMVHASTYGTPVRVAPVNN-APIYNIRRY
MAB_1974|M.abscessus_ATCC_1997 PGDVINFYGDASHTGIYVGNGMMVHASTYGVPVAVVPITSSGPIYNARRY
***::.:*.* **..**:*:* *:*:**** ** *.*: . .**:: ***