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MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVAGQFDGVLLSPGPGTPERAGASVSIVH ACAAAHTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKS LPAVLRVTARTSSGVIMAVQHTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLT AISPHFPTSTASAGEATGRTSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0013 | trpG | - | 100% (232) | para-aminobenzoate synthase component II |
| M. tuberculosis H37Rv | Rv3396c | guaA | 6e-07 | 27.98% (193) | GMP synthase |
| M. tuberculosis H37Rv | Rv1383 | carA | 1e-06 | 28.99% (138) | carbamoyl phosphate synthase small subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0013 | trpG | 1e-134 | 99.57% (232) | para-aminobenzoate synthase component II |
| M. gilvum PYR-GCK | Mflv_0813 | - | 1e-89 | 72.12% (226) | para-aminobenzoate synthase component II |
| M. leprae Br4923 | MLBr_00015 | pabA | 1e-109 | 79.74% (232) | para-aminobenzoate synthase component II |
| M. abscessus ATCC 19977 | MAB_0032 | - | 3e-92 | 76.06% (213) | para-aminobenzoate synthase component II |
| M. marinum M | MMAR_0015 | trpG | 1e-110 | 83.62% (232) | anthranilate synthase component II TrpG |
| M. avium 104 | MAV_0018 | - | 1e-107 | 81.03% (232) | para-aminobenzoate synthase component II |
| M. smegmatis MC2 155 | MSMEG_0029 | - | 5e-94 | 74.11% (224) | para-aminobenzoate synthase component II |
| M. thermoresistible (build 8) | TH_0292 | pabA | 4e-96 | 76.79% (224) | POSSIBLE ANTHRANILATE SYNTHASE COMPONENT II TRPG (GLUTAMINE |
| M. ulcerans Agy99 | MUL_0017 | trpG | 1e-109 | 82.76% (232) | para-aminobenzoate synthase component II |
| M. vanbaalenii PYR-1 | Mvan_0022 | - | 8e-96 | 76.85% (216) | para-aminobenzoate synthase component II |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0013|M.tuberculosis_H37Rv MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF
Mb0013|M.bovis_AF2122/97 MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF
MMAR_0015|M.marinum_M MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLSDEAAIA---AQF
MUL_0017|M.ulcerans_Agy99 MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLCDEAAIA---AQF
MLBr_00015|M.leprae_Br4923 MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIA---AQF
MAV_0018|M.avium_104 MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAVA---RRF
Mflv_0813|M.gilvum_PYR-GCK MQVLVVDNYDSFVFNLVQYLGQLGVEAKVWRNDDERLVTDADIAEVAGDF
Mvan_0022|M.vanbaalenii_PYR-1 MQVLVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDDRLVTDADVSRVAEEF
MSMEG_0029|M.smegmatis_MC2_155 MQVLVVDNYDSFVFNLVQYLGQLGVHAQVWRNDDARLATEDAIAQAAADF
TH_0292|M.thermoresistible__bu VQILVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDARLGTEAAIADAVAAV
MAB_0032|M.abscessus_ATCC_1997 MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVA---ADF
: :**:******************: * ****** ** :: .
Rv0013|M.tuberculosis_H37Rv DGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATV
Mb0013|M.bovis_AF2122/97 DGVLLSPGPGTPERAGASVSMVHACAAAHTPLLGVCLGHQAIGVAFGATV
MMAR_0015|M.marinum_M DGVLLSPGPGTPERAGASVSLVRACAAARTPLLGVCLGHQAIGVAFGATV
MUL_0017|M.ulcerans_Agy99 DGVLLSPGPGTPERAGASVSLVRACAEARTPLLGVCLGHQAIGVAFGATV
MLBr_00015|M.leprae_Br4923 DGILLSPGPGTPERAGASINLVRVCAAAHTPLLGVCLGHQAIGVSFGATV
MAV_0018|M.avium_104 DGVLLSPGPGTPERAGASIAVVRACAAEHTPLLGVCLGHQAIGVAFGATV
Mflv_0813|M.gilvum_PYR-GCK DGVLLSPGPGTPERAGASIPLVHACAEAGTPLLGVCLGHQAIGVAFGGTV
Mvan_0022|M.vanbaalenii_PYR-1 DGVLLSPGPGTPERAGASIGLVHACAAARTPLLGVCLGHQAIGVAFGGTV
MSMEG_0029|M.smegmatis_MC2_155 DGVLLSPGPGTPERAGASIALVKACAAAGTPLLGVCLGHQAIGVAFGGTV
TH_0292|M.thermoresistible__bu DGVLLSPGPGTPERAGASIPVVRACAAAGTPLLGVCLGHQAIGVAFGATV
MAB_0032|M.abscessus_ATCC_1997 DGVLISPGPGTPESAGASIAMVHSCAKTGTPLLGVCLGHQAIGVAFGGTV
**:*:******** ****: :*: ** ***************:**.**
Rv0013|M.tuberculosis_H37Rv DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV
Mb0013|M.bovis_AF2122/97 DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV
MMAR_0015|M.marinum_M DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA
MUL_0017|M.ulcerans_Agy99 DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA
MLBr_00015|M.leprae_Br4923 DRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEV
MAV_0018|M.avium_104 DRAPELLHGKTSSVHHTNAGVLQGLPNPFTATRYHSLTILPESLPPVLEV
Mflv_0813|M.gilvum_PYR-GCK DRAPELLHGKTSTVHHADEGVLKGLPDPFTATRYHSLTILPETVPDELEV
Mvan_0022|M.vanbaalenii_PYR-1 DRAPELLHGKTSTVHHTNQGVLKGLPDPFTATRYHSLTILPETMPAELEV
MSMEG_0029|M.smegmatis_MC2_155 DRAPELLHGKTSVVHHNDSGVLKGLPDPFTATRYHSLTILPETLPAALEV
TH_0292|M.thermoresistible__bu DRAPELLHGKTSTVHHTDVGVLQGLPDPFTATRYHSLTILPQTLPAELEV
MAB_0032|M.abscessus_ATCC_1997 DRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRV
************ * * : ***:***:**************.::* *..
Rv0013|M.tuberculosis_H37Rv TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN
Mb0013|M.bovis_AF2122/97 TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN
MMAR_0015|M.marinum_M TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN
MUL_0017|M.ulcerans_Agy99 TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN
MLBr_00015|M.leprae_Br4923 VART------RSG----VIMAVRHTELPIHGVQFHPESILTEGGHRLLAN
MAV_0018|M.avium_104 TAHT------DSG----VIMGVRHTQLPIHGVQFHPESILTEGGHRMLAN
Mflv_0813|M.gilvum_PYR-GCK IAWTGRGERSDGGEQRGVIMGVRHRDLPIHGVQFHPESILTQGGHRMLAN
Mvan_0022|M.vanbaalenii_PYR-1 TAKT------EGG----VIMGVRHVELPIHGVQFHPESILTQGGHRMLAN
MSMEG_0029|M.smegmatis_MC2_155 VGQT------DNG----IIMAVRHTELPIHGVQFHPESILTQGGHRMLAN
TH_0292|M.thermoresistible__bu TART------AGG----VIMGVRHRELPIHGVQFHPESILTEGGHRMLAN
MAB_0032|M.abscessus_ATCC_1997 IART------ASG----VIMGVMHTEHPIHGVQFHPESILTEGGHRMLAN
. * .* :**.* * **************:****:***
Rv0013|M.tuberculosis_H37Rv WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA---
Mb0013|M.bovis_AF2122/97 WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA---
MMAR_0015|M.marinum_M WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA---
MUL_0017|M.ulcerans_Agy99 WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA---
MLBr_00015|M.leprae_Br4923 WLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA---
MAV_0018|M.avium_104 WLTECGWVRDDTLVRRLENDVHAAVRPYLPADPA----ATDRTSA---
Mflv_0813|M.gilvum_PYR-GCK WLGDCGDAPDEALIRALEEEVETAVAA-----------ATTRNSA---
Mvan_0022|M.vanbaalenii_PYR-1 WLGFCGAAPDEALVRRLEDEVADAVAA-----------ATTRNSA---
MSMEG_0029|M.smegmatis_MC2_155 WLGFCGAAPDETLVRRLEDEVARAVAA-----------ATQRSSA---
TH_0292|M.thermoresistible__bu WLGFCGAAPDDALVRRLEDEVAETVRA-----------ATTRSSA---
MAB_0032|M.abscessus_ATCC_1997 WLTYCGAPLDEPLVRSLEAEVAAALNG-----------VTGRVAALGG
** ** *:.*:* ** :* :: . * *