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M. ulcerans Agy99 MUL_0017 (trpG)

annotation: para-aminobenzoate synthase component II
coordinates: 16022 - 16708
length: 228

MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLCDEAAIAAQFDGVLLSPGPGTPERAGASVSLVR
ACAEARTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDS
LPAELEATAHTRSGVIMGVRHTELPIHGVQFHPESILTEGGHRMLANWLAYCGWARDDTLVRRLENEVAS
AIRPHLPVEAGTTDRTSA

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. ulcerans Agy99 MUL_0017 trpG - 100% (228) para-aminobenzoate synthase component II
M. ulcerans Agy99 MUL_0913 guaA 4e-09 28.57% (196) GMP synthase
M. ulcerans Agy99 MUL_1783 carA 5e-09 31.62% (136) carbamoyl phosphate synthase small subunit

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0013 trpG 1e-109 82.76% (232) para-aminobenzoate synthase component II
M. gilvum PYR-GCK Mflv_0813 - 4e-92 70.95% (241) para-aminobenzoate synthase component II
M. tuberculosis H37Rv Rv0013 trpG 1e-109 82.76% (232) para-aminobenzoate synthase component II
M. leprae Br4923 MLBr_00015 pabA 1e-108 82.02% (228) para-aminobenzoate synthase component II
M. abscessus ATCC 19977 MAB_0032 - 3e-94 74.34% (226) para-aminobenzoate synthase component II
M. marinum M MMAR_0015 trpG 1e-130 99.12% (228) anthranilate synthase component II TrpG
M. avium 104 MAV_0018 - 1e-111 83.33% (228) para-aminobenzoate synthase component II
M. smegmatis MC2 155 MSMEG_0029 - 7e-98 76.19% (231) para-aminobenzoate synthase component II
M. thermoresistible (build 8) TH_0292 pabA 1e-100 84.11% (214) POSSIBLE ANTHRANILATE SYNTHASE COMPONENT II TRPG (GLUTAMINE
M. vanbaalenii PYR-1 Mvan_0022 - 1e-100 77.06% (231) para-aminobenzoate synthase component II

CLUSTAL 2.0.9 multiple sequence alignment


MUL_0017|M.ulcerans_Agy99           MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLCDEAAIA---AQF
MMAR_0015|M.marinum_M               MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLSDEAAIA---AQF
Mb0013|M.bovis_AF2122/97            MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF
Rv0013|M.tuberculosis_H37Rv         MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF
MLBr_00015|M.leprae_Br4923          MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIA---AQF
MAV_0018|M.avium_104                MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAVA---RRF
Mflv_0813|M.gilvum_PYR-GCK          MQVLVVDNYDSFVFNLVQYLGQLGVEAKVWRNDDERLVTDADIAEVAGDF
Mvan_0022|M.vanbaalenii_PYR-1       MQVLVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDDRLVTDADVSRVAEEF
MSMEG_0029|M.smegmatis_MC2_155      MQVLVVDNYDSFVFNLVQYLGQLGVHAQVWRNDDARLATEDAIAQAAADF
TH_0292|M.thermoresistible__bu      VQILVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDARLGTEAAIADAVAAV
MAB_0032|M.abscessus_ATCC_1997      MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVA---ADF
                                    : :**:******************: * ****** **     ::     .

MUL_0017|M.ulcerans_Agy99           DGVLLSPGPGTPERAGASVSLVRACAEARTPLLGVCLGHQAIGVAFGATV
MMAR_0015|M.marinum_M               DGVLLSPGPGTPERAGASVSLVRACAAARTPLLGVCLGHQAIGVAFGATV
Mb0013|M.bovis_AF2122/97            DGVLLSPGPGTPERAGASVSMVHACAAAHTPLLGVCLGHQAIGVAFGATV
Rv0013|M.tuberculosis_H37Rv         DGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATV
MLBr_00015|M.leprae_Br4923          DGILLSPGPGTPERAGASINLVRVCAAAHTPLLGVCLGHQAIGVSFGATV
MAV_0018|M.avium_104                DGVLLSPGPGTPERAGASIAVVRACAAEHTPLLGVCLGHQAIGVAFGATV
Mflv_0813|M.gilvum_PYR-GCK          DGVLLSPGPGTPERAGASIPLVHACAEAGTPLLGVCLGHQAIGVAFGGTV
Mvan_0022|M.vanbaalenii_PYR-1       DGVLLSPGPGTPERAGASIGLVHACAAARTPLLGVCLGHQAIGVAFGGTV
MSMEG_0029|M.smegmatis_MC2_155      DGVLLSPGPGTPERAGASIALVKACAAAGTPLLGVCLGHQAIGVAFGGTV
TH_0292|M.thermoresistible__bu      DGVLLSPGPGTPERAGASIPVVRACAAAGTPLLGVCLGHQAIGVAFGATV
MAB_0032|M.abscessus_ATCC_1997      DGVLISPGPGTPESAGASIAMVHSCAKTGTPLLGVCLGHQAIGVAFGGTV
                                    **:*:******** ****: :*: **   ***************:**.**

MUL_0017|M.ulcerans_Agy99           DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA
MMAR_0015|M.marinum_M               DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA
Mb0013|M.bovis_AF2122/97            DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV
Rv0013|M.tuberculosis_H37Rv         DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV
MLBr_00015|M.leprae_Br4923          DRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEV
MAV_0018|M.avium_104                DRAPELLHGKTSSVHHTNAGVLQGLPNPFTATRYHSLTILPESLPPVLEV
Mflv_0813|M.gilvum_PYR-GCK          DRAPELLHGKTSTVHHADEGVLKGLPDPFTATRYHSLTILPETVPDELEV
Mvan_0022|M.vanbaalenii_PYR-1       DRAPELLHGKTSTVHHTNQGVLKGLPDPFTATRYHSLTILPETMPAELEV
MSMEG_0029|M.smegmatis_MC2_155      DRAPELLHGKTSVVHHNDSGVLKGLPDPFTATRYHSLTILPETLPAALEV
TH_0292|M.thermoresistible__bu      DRAPELLHGKTSTVHHTDVGVLQGLPDPFTATRYHSLTILPQTLPAELEV
MAB_0032|M.abscessus_ATCC_1997      DRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRV
                                    ************ * * : ***:***:**************.::*  *..

MUL_0017|M.ulcerans_Agy99           TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN
MMAR_0015|M.marinum_M               TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN
Mb0013|M.bovis_AF2122/97            TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN
Rv0013|M.tuberculosis_H37Rv         TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN
MLBr_00015|M.leprae_Br4923          VART------RSG----VIMAVRHTELPIHGVQFHPESILTEGGHRLLAN
MAV_0018|M.avium_104                TAHT------DSG----VIMGVRHTQLPIHGVQFHPESILTEGGHRMLAN
Mflv_0813|M.gilvum_PYR-GCK          IAWTGRGERSDGGEQRGVIMGVRHRDLPIHGVQFHPESILTQGGHRMLAN
Mvan_0022|M.vanbaalenii_PYR-1       TAKT------EGG----VIMGVRHVELPIHGVQFHPESILTQGGHRMLAN
MSMEG_0029|M.smegmatis_MC2_155      VGQT------DNG----IIMAVRHTELPIHGVQFHPESILTQGGHRMLAN
TH_0292|M.thermoresistible__bu      TART------AGG----VIMGVRHRELPIHGVQFHPESILTEGGHRMLAN
MAB_0032|M.abscessus_ATCC_1997      IART------ASG----VIMGVMHTEHPIHGVQFHPESILTEGGHRMLAN
                                     . *       .*    :**.* *   **************:****:***

MUL_0017|M.ulcerans_Agy99           WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA---
MMAR_0015|M.marinum_M               WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA---
Mb0013|M.bovis_AF2122/97            WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA---
Rv0013|M.tuberculosis_H37Rv         WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA---
MLBr_00015|M.leprae_Br4923          WLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA---
MAV_0018|M.avium_104                WLTECGWVRDDTLVRRLENDVHAAVRPYLPADPA----ATDRTSA---
Mflv_0813|M.gilvum_PYR-GCK          WLGDCGDAPDEALIRALEEEVETAVAA-----------ATTRNSA---
Mvan_0022|M.vanbaalenii_PYR-1       WLGFCGAAPDEALVRRLEDEVADAVAA-----------ATTRNSA---
MSMEG_0029|M.smegmatis_MC2_155      WLGFCGAAPDETLVRRLEDEVARAVAA-----------ATQRSSA---
TH_0292|M.thermoresistible__bu      WLGFCGAAPDDALVRRLEDEVAETVRA-----------ATTRSSA---
MAB_0032|M.abscessus_ATCC_1997      WLTYCGAPLDEPLVRSLEAEVAAALNG-----------VTGRVAALGG
                                    **  **   *:.*:* ** :*  ::             .  *  *

species	id	gene	e-value	identity (len)	annotation
M. ulcerans Agy99	MUL_0017	trpG	-	100% (228)	para-aminobenzoate synthase component II
M. ulcerans Agy99	MUL_0913	guaA	4e-09	28.57% (196)	GMP synthase
M. ulcerans Agy99	MUL_1783	carA	5e-09	31.62% (136)	carbamoyl phosphate synthase small subunit