For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
QVLVVDNYDSFVFNLVQYLGQLGVEAKVWRNDDERLVTDADIAEVAGDFDGVLLSPGPGTPERAGASIPL VHACAEAGTPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSTVHHADEGVLKGLPDPFTATRYHSLTILP ETVPDELEVIAWTGRGERSDGGEQRGVIMGVRHRDLPIHGVQFHPESILTQGGHRMLANWLGDCGDAPDE ALIRALEEEVETAVAAATTRNSA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0813 | - | - | 100% (234) | para-aminobenzoate synthase component II |
M. gilvum PYR-GCK | Mflv_4903 | guaA | 2e-07 | 28.86% (201) | bifunctional GMP synthase/glutamine amidotransferase protein |
M. gilvum PYR-GCK | Mflv_3744 | - | 1e-06 | 28.47% (144) | carbamoyl phosphate synthase small subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0013 | trpG | 8e-90 | 72.12% (226) | para-aminobenzoate synthase component II |
M. tuberculosis H37Rv | Rv0013 | trpG | 8e-90 | 72.12% (226) | para-aminobenzoate synthase component II |
M. leprae Br4923 | MLBr_00015 | pabA | 2e-89 | 71.56% (225) | para-aminobenzoate synthase component II |
M. abscessus ATCC 19977 | MAB_0032 | - | 2e-92 | 72.22% (234) | para-aminobenzoate synthase component II |
M. marinum M | MMAR_0015 | trpG | 2e-91 | 70.54% (241) | anthranilate synthase component II TrpG |
M. avium 104 | MAV_0018 | - | 2e-90 | 70.95% (241) | para-aminobenzoate synthase component II |
M. smegmatis MC2 155 | MSMEG_0029 | - | 1e-104 | 79.49% (234) | para-aminobenzoate synthase component II |
M. thermoresistible (build 8) | TH_0292 | pabA | 1e-103 | 78.21% (234) | POSSIBLE ANTHRANILATE SYNTHASE COMPONENT II TRPG (GLUTAMINE |
M. ulcerans Agy99 | MUL_0017 | trpG | 3e-92 | 70.95% (241) | para-aminobenzoate synthase component II |
M. vanbaalenii PYR-1 | Mvan_0022 | - | 1e-109 | 83.33% (234) | para-aminobenzoate synthase component II |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0015|M.marinum_M MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLSDEAAIA---AQF MUL_0017|M.ulcerans_Agy99 MPILVVDNYDSFVFNLVQYLGQLGVRAEVWRNDDPRLCDEAAIA---AQF Mb0013|M.bovis_AF2122/97 MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF Rv0013|M.tuberculosis_H37Rv MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA---GQF MLBr_00015|M.leprae_Br4923 MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIA---AQF MAV_0018|M.avium_104 MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAVA---RRF Mflv_0813|M.gilvum_PYR-GCK MQVLVVDNYDSFVFNLVQYLGQLGVEAKVWRNDDERLVTDADIAEVAGDF Mvan_0022|M.vanbaalenii_PYR-1 MQVLVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDDRLVTDADVSRVAEEF MSMEG_0029|M.smegmatis_MC2_155 MQVLVVDNYDSFVFNLVQYLGQLGVHAQVWRNDDARLATEDAIAQAAADF TH_0292|M.thermoresistible__bu VQILVVDNYDSFVFNLVQYLGQLGVDAQVWRNDDARLGTEAAIADAVAAV MAB_0032|M.abscessus_ATCC_1997 MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVA---ADF : :**:******************: * ****** ** :: . MMAR_0015|M.marinum_M DGVLLSPGPGTPERAGASVSLVRACAAARTPLLGVCLGHQAIGVAFGATV MUL_0017|M.ulcerans_Agy99 DGVLLSPGPGTPERAGASVSLVRACAEARTPLLGVCLGHQAIGVAFGATV Mb0013|M.bovis_AF2122/97 DGVLLSPGPGTPERAGASVSMVHACAAAHTPLLGVCLGHQAIGVAFGATV Rv0013|M.tuberculosis_H37Rv DGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATV MLBr_00015|M.leprae_Br4923 DGILLSPGPGTPERAGASINLVRVCAAAHTPLLGVCLGHQAIGVSFGATV MAV_0018|M.avium_104 DGVLLSPGPGTPERAGASIAVVRACAAEHTPLLGVCLGHQAIGVAFGATV Mflv_0813|M.gilvum_PYR-GCK DGVLLSPGPGTPERAGASIPLVHACAEAGTPLLGVCLGHQAIGVAFGGTV Mvan_0022|M.vanbaalenii_PYR-1 DGVLLSPGPGTPERAGASIGLVHACAAARTPLLGVCLGHQAIGVAFGGTV MSMEG_0029|M.smegmatis_MC2_155 DGVLLSPGPGTPERAGASIALVKACAAAGTPLLGVCLGHQAIGVAFGGTV TH_0292|M.thermoresistible__bu DGVLLSPGPGTPERAGASIPVVRACAAAGTPLLGVCLGHQAIGVAFGATV MAB_0032|M.abscessus_ATCC_1997 DGVLISPGPGTPESAGASIAMVHSCAKTGTPLLGVCLGHQAIGVAFGGTV **:*:******** ****: :*: ** ***************:**.** MMAR_0015|M.marinum_M DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA MUL_0017|M.ulcerans_Agy99 DRAPELLHGKTSSVYHTNVGVLQGLPDPFTATRYHSLTILPDSLPAELEA Mb0013|M.bovis_AF2122/97 DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV Rv0013|M.tuberculosis_H37Rv DRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRV MLBr_00015|M.leprae_Br4923 DRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEV MAV_0018|M.avium_104 DRAPELLHGKTSSVHHTNAGVLQGLPNPFTATRYHSLTILPESLPPVLEV Mflv_0813|M.gilvum_PYR-GCK DRAPELLHGKTSTVHHADEGVLKGLPDPFTATRYHSLTILPETVPDELEV Mvan_0022|M.vanbaalenii_PYR-1 DRAPELLHGKTSTVHHTNQGVLKGLPDPFTATRYHSLTILPETMPAELEV MSMEG_0029|M.smegmatis_MC2_155 DRAPELLHGKTSVVHHNDSGVLKGLPDPFTATRYHSLTILPETLPAALEV TH_0292|M.thermoresistible__bu DRAPELLHGKTSTVHHTDVGVLQGLPDPFTATRYHSLTILPQTLPAELEV MAB_0032|M.abscessus_ATCC_1997 DRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRV ************ * * : ***:***:**************.::* *.. MMAR_0015|M.marinum_M TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN MUL_0017|M.ulcerans_Agy99 TAHT------RSG----VIMGVRHTELPIHGVQFHPESILTEGGHRMLAN Mb0013|M.bovis_AF2122/97 TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN Rv0013|M.tuberculosis_H37Rv TART------SSG----VIMAVQHTGLPIHGVQFHPESILTEGGHRILAN MLBr_00015|M.leprae_Br4923 VART------RSG----VIMAVRHTELPIHGVQFHPESILTEGGHRLLAN MAV_0018|M.avium_104 TAHT------DSG----VIMGVRHTQLPIHGVQFHPESILTEGGHRMLAN Mflv_0813|M.gilvum_PYR-GCK IAWTGRGERSDGGEQRGVIMGVRHRDLPIHGVQFHPESILTQGGHRMLAN Mvan_0022|M.vanbaalenii_PYR-1 TAKT------EGG----VIMGVRHVELPIHGVQFHPESILTQGGHRMLAN MSMEG_0029|M.smegmatis_MC2_155 VGQT------DNG----IIMAVRHTELPIHGVQFHPESILTQGGHRMLAN TH_0292|M.thermoresistible__bu TART------AGG----VIMGVRHRELPIHGVQFHPESILTEGGHRMLAN MAB_0032|M.abscessus_ATCC_1997 IART------ASG----VIMGVMHTEHPIHGVQFHPESILTEGGHRMLAN . * .* :**.* * **************:****:*** MMAR_0015|M.marinum_M WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA--- MUL_0017|M.ulcerans_Agy99 WLAYCGWARDDTLVRRLENEVASAIRPHLPVEAG----TTDRTSA--- Mb0013|M.bovis_AF2122/97 WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA--- Rv0013|M.tuberculosis_H37Rv WLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA--- MLBr_00015|M.leprae_Br4923 WLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA--- MAV_0018|M.avium_104 WLTECGWVRDDTLVRRLENDVHAAVRPYLPADPA----ATDRTSA--- Mflv_0813|M.gilvum_PYR-GCK WLGDCGDAPDEALIRALEEEVETAVAA-----------ATTRNSA--- Mvan_0022|M.vanbaalenii_PYR-1 WLGFCGAAPDEALVRRLEDEVADAVAA-----------ATTRNSA--- MSMEG_0029|M.smegmatis_MC2_155 WLGFCGAAPDETLVRRLEDEVARAVAA-----------ATQRSSA--- TH_0292|M.thermoresistible__bu WLGFCGAAPDDALVRRLEDEVAETVRA-----------ATTRSSA--- MAB_0032|M.abscessus_ATCC_1997 WLTYCGAPLDEPLVRSLEAEVAAALNG-----------VTGRVAALGG ** ** *:.*:* ** :* :: . * *