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M. vanbaalenii PYR-1 Mvan_6064 (-)

annotation: integral membrane protein MviN
coordinates: 6477501 - 6481175
length: 1224

MRDAAPRRAPTRRPRSSPPPPPPPPRRPQAARPEMSDAAVVSRSWGMALATLVSRLTGFARIVLLAAILG
AALSSAFTVANQLPNMIAALVLEATFTAIFVPVLARAERDDPDGGAAFIRRLLTLATTLLLVVTIISTVA
APLLVDLMLGPDPLVDRPLTTAFAYLLLPQIIFYGLSSVFMAILNTRNVFGPPAWAPVVNNVVAILTLGL
YVLVPGELSLNPVQMGDAKLLVLGVGTTLGVVAQAGVLFMAIRRQRVSLRPLWGIDARLKKFGMMAVAMV
LYVLISQVGFIVGNQVASTAAASGPAIYNYTWLILQLPFGIVGVTVLTVVMPRLSRNAAADDAPAVLADL
SLATRLTMITLIPIVAMMTVGGPAIGSALFSYGNFGAVDAGYLGMAITLSAFTLIPYTLVLLQLRVFYAR
EEPWTPILLIIVITIVKIAASLAAPHLTADPQLVAGYLGLANGLGFLAGATVGYLLLRARLDPPGGRLLD
NAVIRTILVTITASLAAGLTAHVVDQLAGLENLTTHWGAAGSLLRLLALGLVMVPIIAAVMLTAKVPEAQ
AALAAVRRRLGTRGPAAEPSVRPRPSDTLTYPDHKNRSSLRRRQLPRSAARGPSAEAADDGRRKGFAVSD
KPTSGSPGGPDSAATTRITRPSPDDFQPDVPEDAGTHVLPQAPARPTGPESAARPTGPESAARPAGPESA
ARPPVSDYAGDPTREALPFDPPREPATEAATTAEDMHLIPGATIVDGRYRLLVSHGGPAHLQFWQALDTA
LDRQVALTFVDPDATMPDRAVQEILDRTQRLSRIDMPGVARVLDVVSTGVGGLVVSEWIRGGSLAEVADT
CPSPIGGARAIQSLAAAAEVAHRNGVALSIDHPSRIRVSIDGDVALAFPATLPDASPDDDIRGIGASLYA
LLVNRWPLPETGEPSGLAPADLDAAGQPVEPRSVDRDIPFQISAAAAHAVQEGGGIRSAPTLLNLLQQAT
AIADRTDHIAPVDDPAPPPSGAGFAAELDPEAAARRRKGLIVGLSVAGAIAVIAVVLLATVLSRIFGDVG
DGLGGDELGLNSPSSSTTAQPGQSGSALKPVSVTVFSPEGEADAPKLAGLAIDGNPATVWPIDTYTDAAP
FPNFKNGVGLMLQLPEPAKIGSVTVNLNSTGTSVQIRSSETATPSSLEDTTALTDPTPVKPGSNTIEVED
AEPTSYVLVWISTLGQVDGESRSDIAEVTLNAAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_6064--100% (1224)integral membrane protein MviN
M. vanbaalenii PYR-1Mvan_3539-7e-0830.26% (152) protein kinase
M. vanbaalenii PYR-1Mvan_5401-8e-0723.37% (338) protein kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3940-0.064.86% (1215) transmembrane protein
M. gilvum PYR-GCKMflv_0842-0.079.77% (1221) integral membrane protein MviN
M. tuberculosis H37RvRv3910-0.064.86% (1215) transmembrane protein
M. leprae Br4923MLBr_02700-0.060.48% (1212) hypothetical protein MLBr_02700
M. abscessus ATCC 19977MAB_4937-0.051.51% (1225) hypothetical protein MAB_4937
M. marinum MMMAR_5474-0.065.65% (1208) transmembrane protein
M. avium 104MAV_5298-0.063.41% (1238) virulence factor mvin family protein
M. smegmatis MC2 155MSMEG_6929-0.069.98% (1236) integral membrane protein MviN, putative
M. thermoresistible (build 8)TH_2415-0.065.02% (626) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_5063-0.064.86% (1218) transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_6064|M.vanbaalenii_PYR-1       ------------MRDAAPRRAPTRRPRSSPPPPPPPPRRPQAARPEMSDA
Mflv_0842|M.gilvum_PYR-GCK          ---------------------------------------MPDARPEMSDR
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      -----------------MNATQPQRPPGPRRLPRGPAPRRRAGQEELSDA
Mb3940|M.bovis_AF2122/97            -------------------------MRPSPGEVPTASQ----RQPELSDA
Rv3910|M.tuberculosis_H37Rv         -------------------------MRPSPGEVPTASQ----RQPELSDA
MMAR_5474|M.marinum_M               ---------------------------MPYGQAAAGPP----KRAELSDA
MUL_5063|M.ulcerans_Agy99           ---------------------------MPYGPAAAGPP----KRAELSDA
MAV_5298|M.avium_104                MNPAYRQAAPHHRRLPEPPRRPRMPGSPPTGPLPPVPAGIDRRRPELSDS
MLBr_02700|M.leprae_Br4923          --------------MKPAPRWTQSQSAQQVTHAMRPCRELSAQQPELSDA
MAB_4937|M.abscessus_ATCC_1997      ---------------------------MREPLDPLPDPEADDTIEELSDA
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       AVVSRSWGMALATLVSRLTGFARIVLLAAILGAALSSAFTVANQLPNMIA
Mflv_0842|M.gilvum_PYR-GCK          AVVSRSWGMAVATLVSRLTGFARIVLLAAILGAALSSAFTVANQLPNMIA
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      AVVSRSWGMAMATLISRITGFIRIVLLAAILGAALSSAFSVANQLPNLIA
Mb3940|M.bovis_AF2122/97            ALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVA
Rv3910|M.tuberculosis_H37Rv         ALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVA
MMAR_5474|M.marinum_M               ALVSRSWGMALATLVSRITGFARIVLLAAILGAALSSSFSVANQLPNLVA
MUL_5063|M.ulcerans_Agy99           ALVSRSWGMALATLVSRITGFARIVLLAAILGAALSSSFSVANQLPNLVA
MAV_5298|M.avium_104                ALVSRSWAMAFATLVSRLTGFARVVLLAAILGAALSSAFSVANQLPNLVA
MLBr_02700|M.leprae_Br4923          ALVSRSWAMAFATLISRITGFARVVLLAAILGAALSSAFSVANQLPNLVA
MAB_4937|M.abscessus_ATCC_1997      AVVSHSGSMAVATLVSRITGFIKLLLITAALGAASASAFSTANTLPNIIA
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       ALVLEATFTAIFVPVLARAERDDPDGGAAFIRRLLTLATTLLLVVTIIST
Mflv_0842|M.gilvum_PYR-GCK          ALVLEATFTAIFVPVLARAERDDPDGGAAFIRRLLTLATALLLAVTIIST
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      ALVLEATFTAIFVPVLARAERDDPDGGAAFVRRLVTLVTTLLLVTTLVSV
Mb3940|M.bovis_AF2122/97            ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSV
Rv3910|M.tuberculosis_H37Rv         ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSV
MMAR_5474|M.marinum_M               ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLTTTLLIVATTLSV
MUL_5063|M.ulcerans_Agy99           ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLTTALLIVATTLSV
MAV_5298|M.avium_104                ALVLEATFTAIFVPVLARAEQSDPDGGAAFVRRLVTLTTALLIVATALSV
MLBr_02700|M.leprae_Br4923          ALVLEATFTAIFVPVLVRAERSDPDGGTAFVRQLITLTTTLLLLSTTLSV
MAB_4937|M.abscessus_ATCC_1997      ALVLEATFTAIFIPVLTRAEREDADGGEAFIRKLLTIVTTLLLVTTLLSV
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       VAAPLLVDLMLGPDPLVDRPLTTAFAYLLLPQIIFYGLSSVFMAILNTRN
Mflv_0842|M.gilvum_PYR-GCK          VGAPLLVNLMLGSEPLVNQPLTTAFAFLLLPQIIFYGLSSVFMAILNTRN
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      AAAPALVRLMLGDDPQVNEPLTTAFAYLLLPQVLFYGLSSVFMAILNTRN
Mb3940|M.bovis_AF2122/97            LAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
Rv3910|M.tuberculosis_H37Rv         LAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
MMAR_5474|M.marinum_M               LAAPLLVRLMLGRDPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
MUL_5063|M.ulcerans_Agy99           LAAPLLVRLMLGRDPQVNEPLTTAFAYLLLPQVLVYGLSSVFIAILNTRN
MAV_5298|M.avium_104                AAAPLLVRLMLGRTPQVNEPLTVAFAYLLLPQVLAYGLTSVFMAILNTRN
MLBr_02700|M.leprae_Br4923          LAAPLLVRLMLGRNPQVNEPLTTAFAYLLLPQVLAYGLSSVFMAILNTRN
MAB_4937|M.abscessus_ATCC_1997      LAAPLLAGIMLGGDPKVNTPLTTALAYLLLPQVFFYGLSSLFMAILNTRN
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       VFGPPAWAPVVNNVVAILTLGLYVLVPGELSLNPVQMGDAKLLVLGVGTT
Mflv_0842|M.gilvum_PYR-GCK          IFGPPAWAPVVNNVVAIATLGLYVLVPGELSLDPVRMGDAKLLVLGIGTT
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      VFGPPAWAPVLNNVVAIATLGAYLLVPGELSVDPVQMGNAKLLVLGVGTT
Mb3940|M.bovis_AF2122/97            VFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTT
Rv3910|M.tuberculosis_H37Rv         VFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTT
MMAR_5474|M.marinum_M               VFGPPAWAPVINNVVAIATLLVYLAVPGELAIDPVKMGNAKLLVLGVGTT
MUL_5063|M.ulcerans_Agy99           VFGPPAWAPVINNGVAIATLLVYLAVPGELAVDPVKMGNAKLLVLGVGTT
MAV_5298|M.avium_104                VFGPTAWAPVVNNVVALATLAVYALVPGELSVDPVRMGNAKLLVLAVGTT
MLBr_02700|M.leprae_Br4923          VFGPPAWAPVINNIVAIAALVGYLVTPGELSVDPVRMGNAKLLVLGIGTT
MAB_4937|M.abscessus_ATCC_1997      VFGPPAWAPVWNNLVAIATLVLYWLMPGELTLDPIRMSDPKLLVLGIGTT
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       LGVVAQAGVLFMAIRRQRVSLRPLWGIDARLKKFGMMAVAMVLYVLISQV
Mflv_0842|M.gilvum_PYR-GCK          LGVVAQAAVLFVAIRRERISLRPLWGIDARLKKFGMMALAMVLYVLVSQV
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      LGVVAQCSVLLPAIRRERISLRPLWGIDDRLKKFGAMAAAMVLYVLISQI
Mb3940|M.bovis_AF2122/97            AGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQL
Rv3910|M.tuberculosis_H37Rv         AGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQL
MMAR_5474|M.marinum_M               LGVFAQAAVLLVAIGRQHISLRPLWGIDDRLKRFGAMAAAMVLYVLISQL
MUL_5063|M.ulcerans_Agy99           LGVFAQAAVLLVAIGRQHISLRPLWGIDDRLKRFGAMAAAMVLYVLVSQL
MAV_5298|M.avium_104                LGVFAQTGVLLVALRRQHVDLRPLWGIDQRLKRFGTLAAAMVLYVLISQL
MLBr_02700|M.leprae_Br4923          AGAFAQTAVLLVALGREHISLHPLWGLDQRLKRFGAMATAMVLYVLISQL
MAB_4937|M.abscessus_ATCC_1997      LGVAAQAMVLLPAIRRQQIPLRPLWGLDDRLKQFGGMAAAMFAYVAISQF
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       GFIVGNQVASTAAASGPAIYNYTWLILQLPFGIVGVTVLTVVMPRLSRNA
Mflv_0842|M.gilvum_PYR-GCK          GFIVGNQVASASAASGPAIYNYTWLILQLPFGIVGVTVLTVVMPRLSRNA
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      GLVVGNQIASGAAASGPAIYNYAWLVLQLPFGMIGVTVLTVVMPRLSRNA
Mb3940|M.bovis_AF2122/97            GLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
Rv3910|M.tuberculosis_H37Rv         GLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MMAR_5474|M.marinum_M               GLIVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MUL_5063|M.ulcerans_Agy99           GLIVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MAV_5298|M.avium_104                GLVVGNQIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MLBr_02700|M.leprae_Br4923          GLVVTNQIASTTAASGPAIYNYTWLVLMLPFGIIGVTVLTVVMPRLSRNA
MAB_4937|M.abscessus_ATCC_1997      GYVIANRIAAGAAESGPIIYSQTWMILQLPYGVVGVTILTAIMPRLSRNA
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       AADDAPAVLADLSLATRLTMITLIPIVAMMTVGGPAIGSALFSYGNFGAV
Mflv_0842|M.gilvum_PYR-GCK          ASGDGGAVLADLSLATRLTMLTLIPIVALMTVGGPAIGSALFSYGNFGAV
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      AKNDIPAVLGDLSLATRLTMITLIPIVALMTVGGPAIGTALFAYGNFGRV
Mb3940|M.bovis_AF2122/97            AADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDV
Rv3910|M.tuberculosis_H37Rv         AADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDV
MMAR_5474|M.marinum_M               AAEDIPAVLADLSLATRLTMITLIPTVAFMTVGGSAMGSALFAYGNFGKV
MUL_5063|M.ulcerans_Agy99           AAEDILAVLADLSLATRLTMITLIPTVAFMTVGGSAMGSALFAYGNFGKV
MAV_5298|M.avium_104                AADDTRAVLADLSLATRLTLITLIPIVAFMTVGGPAMGSALFAYGHFGDV
MLBr_02700|M.leprae_Br4923          AANDTPAMLADLSLATRLTLITLIPTVAFMTAGGSAMGSVLFAYGHFGEV
MAB_4937|M.abscessus_ATCC_1997      AAQDTPAVLGDMSLATRLTMTVLIPVVAVMTVAGPAMGPALFAYGNFHLG
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       DAGYLGMAITLSAFTLIPYTLVLLQLRVFYAREEPWTPILLIIVITIVKI
Mflv_0842|M.gilvum_PYR-GCK          DAGYLGMAITLSAFTLIPYTMVLLQLRVFYAREEPWTPIVLIVVITIVKI
TH_2415|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6929|M.smegmatis_MC2_155      DAGYLGLAISLSAFTLIPYALVLLQLRVFYARERAWTPIIVIIVITVVKI
Mb3940|M.bovis_AF2122/97            DAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKI
Rv3910|M.tuberculosis_H37Rv         DAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKI
MMAR_5474|M.marinum_M               DAGYLGAAIALSAFTLIPYALVLLGLRVFYAREQPWTPILIIIIITSVKI
MUL_5063|M.ulcerans_Agy99           DAGYLGAAIALSAFTLIPYALVLLGLRVFYAREQPWTPILIIIIITSVKI
MAV_5298|M.avium_104                DAGYLGAAIALSAFTLIPYGLVLLQLRVFYAREQPWTPIVIILVITAVKI
MLBr_02700|M.leprae_Br4923          DAGYLGTAIVLSAFTLIPYGLVLLQLRVFYAREQPWTPIVIIVVITAVRI
MAB_4937|M.abscessus_ATCC_1997      SAHYLGLSISLSAFTLIPYALVLLQLRVFYARHEAWTPTLMIIVITAVKV
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       AASLAAPHLTADPQLVAGYLGLANGLGFLAGATVGYLLLRARLDPPGGRL
Mflv_0842|M.gilvum_PYR-GCK          AASLASPHLTDDPQLVAGYLGLANGLGFLAGATVGYLLLRARLDPPGGHL
TH_2415|M.thermoresistible__bu      --------VTDDP---------ATGAAPTPDRTT-----TTRLPRPSAAE
MSMEG_6929|M.smegmatis_MC2_155      AGSVAAPHLTNNPEMVAGYLGAANGLGFMAGAIVGHVLLRANLDPPGGRL
Mb3940|M.bovis_AF2122/97            LGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQL
Rv3910|M.tuberculosis_H37Rv         LGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQL
MMAR_5474|M.marinum_M               GASVLAPHLTNDPDMVAGYLGLANGLGFLAGAIVGYYLLRRALRPGGGQL
MUL_5063|M.ulcerans_Agy99           GASVLAPHLTNDPDMVAGYLGLANGLGFLAGAIVGYYLLRRALCPGGGQL
MAV_5298|M.avium_104                LGSVLAPHLTGDPKLVAGFLGLANGVGFLAGAVIGYVLLRRTLLPGGGHL
MLBr_02700|M.leprae_Br4923          IVSVLAPYVISNPELVAGYLGMANGLGFAAGAIVGYYLLRRALLPTGGHL
MAB_4937|M.abscessus_ATCC_1997      IGSVAAPHLTDDPDLVAGYLGAANGLGFVAGALCGYLLLRRSLGRAAGPL
                                            :  :*         *.* .  ..           *   ..  

Mvan_6064|M.vanbaalenii_PYR-1       LDNAVIRTILVTITASLAAGLTAHVVDQLAGLENLTTHWGAAGSLLRLLA
Mflv_0842|M.gilvum_PYR-GCK          VSRDVVRTILVTITASLAAGLIAHIADQILGLEQLTEHWGGGGSLIRLAV
TH_2415|M.thermoresistible__bu      SSR----------SASLAG-------------------------------
MSMEG_6929|M.smegmatis_MC2_155      VSLTVVRTILVTITASLLAVLVSVVVDQLLGVEQLTVRFGAGGSMIRLVV
Mb3940|M.bovis_AF2122/97            IGVGEARTALVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSV
Rv3910|M.tuberculosis_H37Rv         IGVGEARTVLVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSV
MMAR_5474|M.marinum_M               VGTREVHTILVTIAASLLAGLLAYVVDRLAGLGQLTVFGGGIGSLLRLLI
MUL_5063|M.ulcerans_Agy99           VGTREVHTILVTIAASLLAGLLAYVVDRLAGLGQLTVFDGGIGSLLRLLI
MAV_5298|M.avium_104                IGVGEVRTILVTLTAAMLAGLVAHVADRLLGLSALTAHGGGAGSLLRLLV
MLBr_02700|M.leprae_Br4923          FGVQEIRTVLVTIAASLLAGLAAHIADRLLRLNELTMHGGGAGSLLRLTV
MAB_4937|M.abscessus_ATCC_1997      IGPDVARTALVALAASVTAAAVGLGIDRGFGLDLLTQRGGGLGSILRLAI
                                     .           :*:: .                               

Mvan_6064|M.vanbaalenii_PYR-1       LGLVMVPIIAAVMLTAKVPEAQAALAAVRRRLGTRGPAAEPSVRPRPSDT
Mflv_0842|M.gilvum_PYR-GCK          LGLVMGPIILGVLIAAKVPDALAGVAAVRRRLGARGATTGSPVPQMSPRA
TH_2415|M.thermoresistible__bu      -------------------------------------EARPSADDFEPDV
MSMEG_6929|M.smegmatis_MC2_155      LGLIMLPIIAGVLIAAKVPEAQAAIRVVRGRLGRFGGKETPAVDAAEKVA
Mb3940|M.bovis_AF2122/97            LALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQTQNVLDQS
Rv3910|M.tuberculosis_H37Rv         LALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQTQNVLDQS
MMAR_5474|M.marinum_M               LGVIMAPIVIAVLLAGQVPEAQAALNVVRNRIGTRLGKPGPRSVAVPDAS
MUL_5063|M.ulcerans_Agy99           LGVIMAPIVIAVLLAGQVPEAQAALNVVRNRIGTRLGKPGPRSVAVLDPS
MAV_5298|M.avium_104                LALIMVPITAAVMLRAQVPEARAALDAVRFRITGR--GPRPRKPAAPDRS
MLBr_02700|M.leprae_Br4923          LTSIMLPTMAVVMLRGHVPEVHAALGAVRGQIMSRNWIAKLQKATVPDQS
MAB_4937|M.abscessus_ATCC_1997      LGIVMLAVTFALMVAVKLPEALSVVAMLQRRLGGR-LGARLRAETQDHAS
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       LTYPDHKNRSSLRRRQLPRSAARGPSAEAADDGRRKGFAVSDKPTSGSPG
Mflv_0842|M.gilvum_PYR-GCK          LTYADRSNR-------------RGPSAETADDGRRKGSAVSDKPTSDSPS
TH_2415|M.thermoresistible__bu      LEAD-------------------GGGAHPAD-------------------
MSMEG_6929|M.smegmatis_MC2_155      LQTNGPAVPPR-----------TAGAVTYPDQRNSSPGRGPTTPAPGWVG
Mb3940|M.bovis_AF2122/97            SRPG--------------------PVTYPERRRLAPPRGKSVVHEPIRRR
Rv3910|M.tuberculosis_H37Rv         SRPG--------------------PVTYPERRRLAPPRGKSVVHEPIRRR
MMAR_5474|M.marinum_M               SGDH--------------------DVTYPEQRKSSLP-GENVVQEPIRRK
MUL_5063|M.ulcerans_Agy99           SGDH--------------------DVTYPEQRKSSLP-GENVVQEPIRRK
MAV_5298|M.avium_104                SHRR--------------------PVTYPEQRNSSPP-GVNAVQEPIRRR
MLBr_02700|M.leprae_Br4923          SRPI--------------------TVTYPGQNNSSPP-RVNAIQESIRSR
MAB_4937|M.abscessus_ATCC_1997      VMGN----------------------------------------------
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       GPDSAATTR----------------------ITRPSPDDFQPDVPEDAGT
Mflv_0842|M.gilvum_PYR-GCK          GPDSTAPPSGPNSTAPPSGPNSTAPPSGPNSTAPPSADDFQPDVPDSYQP
TH_2415|M.thermoresistible__bu      GP---------------------------------------PEVAG----
MSMEG_6929|M.smegmatis_MC2_155      APASVAGAG----------------TRKGSPVTDESAGGPALDGTATTKL
Mb3940|M.bovis_AF2122/97            PPEQVARAG---------------------RAKGPEVIDRPSE-NASFG-
Rv3910|M.tuberculosis_H37Rv         PPEQVARAG---------------------RAKGPEVIDRPSE-NASFG-
MMAR_5474|M.marinum_M               PP--VIRAG---------------------IAKGPSVTDRPSDSTASSS-
MUL_5063|M.ulcerans_Agy99           PP--VIRAG---------------------IAKGPSVTDRPSDSTASSS-
MAV_5298|M.avium_104                PPERANRAR---------------------LVKGPEVTDRPMESAASSAG
MLBr_02700|M.leprae_Br4923          PPERIAKAQ---------------------IAKGPEVSDRPVESASSRSA
MAB_4937|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mvan_6064|M.vanbaalenii_PYR-1       HVLPQAPARPTGPESAARPTGPESAARPAG--PESAARPPVSDYAGDPTR
Mflv_0842|M.gilvum_PYR-GCK          DPAADDSATTALP-AQGVPTQSPSKSPTET--PTEAVKRPRADYSNDPTR
TH_2415|M.thermoresistible__bu      ---ATESVDRRAIDRRAIDTGTAATTETAR--PVMSGRPP-ADYGGDPSR
MSMEG_6929|M.smegmatis_MC2_155      PRQAPDDFQPDVADDESEAAGAEPTVEETVSLPNGSGRPP-ADYGGDPTR
Mb3940|M.bovis_AF2122/97            AASGA--ELPRPVADELQLDAPAG-RDPGPVSRPHPSDLQNGDLPADAAR
Rv3910|M.tuberculosis_H37Rv         AASGA--ELPRPVADELQLDAPAG-RDPGPVSRPHPSDLQNGDLPADAAR
MMAR_5474|M.marinum_M               SASDI--DLPRPVADDFQPDIPAG-PDRGRGASQRPSDQSNGDS-VGYTR
MUL_5063|M.ulcerans_Agy99           SASDI--DLPRPVADDFQPDIPAG-PDRGRGASLRPSDLSNGDS-VGYTR
MAV_5298|M.avium_104                PGTGS--GAPRPVADDFQPDIPADQPDRPRKADPRPADQKNGDA--GTRR
MLBr_02700|M.leprae_Br4923          SDTGLPSELPRPVAGNSQPYISAN-LELEHVASLHPPEQQKVDFPAYPAR
MAB_4937|M.abscessus_ATCC_1997      ---SPGPSLPYPDSGDPVGGSDAIGSTTAN----KPAHGGGADTRKGRAV
                                                                       .      *       

Mvan_6064|M.vanbaalenii_PYR-1       EALPFDPPR-EPATEAATTAEDMHLIPGATIVDGRYRLLVSHGGPAHLQF
Mflv_0842|M.gilvum_PYR-GCK          EALAFDPPR-EPAIETATPAEDTHLIPGATIAGGRYRLLVSHGGPEHLQF
TH_2415|M.thermoresistible__bu      EPLAFDYPR-EPAIEAATAEEDVHLIPGATVGGGRYRLLVFHGGPEHLQF
MSMEG_6929|M.smegmatis_MC2_155      EPISFAPPR-EPAVESATSGDDVHLIPGATIADGRYRLLVFHGGPPHLQF
Mb3940|M.bovis_AF2122/97            GPIAFDALR-EPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVPPLQF
Rv3910|M.tuberculosis_H37Rv         GPIAFDALR-EPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVPPLQF
MMAR_5474|M.marinum_M               GPIPFDAPR-ERSAEPSTPQDDVNLVPGARIANGRYRLLVFHGGIPPLQF
MUL_5063|M.ulcerans_Agy99           GPIPFDAPR-ECSAEPSTPQDDVNLVPGARIANGRYRLLVFHGGIPPLQF
MAV_5298|M.avium_104                G--PFDVPR-ERAADSSA--DDVHLVPGARIAGGRYRLLVFHGGAPPLQF
MLBr_02700|M.leprae_Br4923          RPIRFEVSR-ERGGEQSSPTGDVHLVPGACIAGGRYRLLAFHGGAPSLQF
MAB_4937|M.abscessus_ATCC_1997      TDTPGSSTRPVPTQSPSTGPVPTSVMPGASIAGGRYRLLTSHGGPDGLQF
                                            *     . ::      ::*** : .******  ***   ***

Mvan_6064|M.vanbaalenii_PYR-1       WQALDTALDRQVALTFVDPDATMPDRAVQEILDRTQRLSRIDMPGVARVL
Mflv_0842|M.gilvum_PYR-GCK          WQATDTALDRQVALTFVAPDATMPDQQVQGILDRTQRLSQIDMPGVARVL
TH_2415|M.thermoresistible__bu      WQALDTALDRQVALTFVDPDAMLPDEQVQQILSRTLKLSRLNMPGIARVL
MSMEG_6929|M.smegmatis_MC2_155      WQALDTALDRQVALTFVDPDAKLPDSQVQDILSRTLKLSRLDVPGIARVL
Mb3940|M.bovis_AF2122/97            WQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVL
Rv3910|M.tuberculosis_H37Rv         WQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVL
MMAR_5474|M.marinum_M               WQALDTALDRQVALTFVDPDGTLPEDVLQEILARTLRLSRIDKPGVARVL
MUL_5063|M.ulcerans_Agy99           WQALDTALDRQVALTFVDPDGTLPEDVLQEILARTLRLSRIDKPGVARVL
MAV_5298|M.avium_104                WQALDTALDRQVALTFVDPDRALPDEVLQEILSRTLRLSRIDKPGIARVL
MLBr_02700|M.leprae_Br4923          WQALDTALDRQVALTFVNPDGALPDDSLQETLSRTLRLSRIDMPGVAQVL
MAB_4937|M.abscessus_ATCC_1997      WQATDTELNRPVALTIIDG-AAFTADQVQDILSNTLRLSKIESSGLARVL
                                    *** ** *:* ****::     :.   :*  * .* :**::: .*:*:**

Mvan_6064|M.vanbaalenii_PYR-1       DVVSTGVGGLVVSEWIRGGSLAEVADTCPSPIGGARAIQSLAAAAEVAHR
Mflv_0842|M.gilvum_PYR-GCK          DVLKTATGGLVVSEWIRGGSLAEVAATNPSPIGGARAIQSLAAAAEVAHR
TH_2415|M.thermoresistible__bu      DVLNTGSGGLIVSEWIRGGSLAEVADTSPSPIGGARAIQSLAAAAEAAHR
MSMEG_6929|M.smegmatis_MC2_155      DVAHSGSGGLIVSEWIRGGSLAEVADTAPSPIGGARAIQSLAAAAEAAHR
Mb3940|M.bovis_AF2122/97            DVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHR
Rv3910|M.tuberculosis_H37Rv         DVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHR
MMAR_5474|M.marinum_M               DVLHTASGGLVVSEWIRGGSLQEVADTAPSPVGAIRAMQSLAAAADAAHR
MUL_5063|M.ulcerans_Agy99           DVLHTASGGLVVSEWIRGGSLQEVADTAPSPVGAIRAIQSLAAAADAAHR
MAV_5298|M.avium_104                DVVHTGSGGLVVSEWIRGGSLQEVADTAPSPVGAVRAMQSLAAAADAAHR
MLBr_02700|M.leprae_Br4923          DVIHTGSGGLVVSEWIRGGSLHEVADTSPSPVGAIRAMQSLAAAADAAHR
MAB_4937|M.abscessus_ATCC_1997      DAVHEGNGGIVVAQWVRGGSLREVADTEPSAVGASRAVRSLAEAADAAFE
                                    *.     **::*::*:***** *** * **.:*. **::*** **:.*..

Mvan_6064|M.vanbaalenii_PYR-1       NGVALSIDHPSRIRVSIDGDVALAFPATLPDASPDDDIRGIGASLYALLV
Mflv_0842|M.gilvum_PYR-GCK          NGVALSIDHPSRIRVSIDGDVALAFPATLPDATPDDDIRGIGASLYALLI
TH_2415|M.thermoresistible__bu      DGVALSIDHPARVRVSIEGDVALAFPATMPDAEPEDDIRGIGAALYALLI
MSMEG_6929|M.smegmatis_MC2_155      AGVALSIDHPSRVRVSIEGDVALAFPATLPDATPDDDIRGIGAALYALLV
Mb3940|M.bovis_AF2122/97            AGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLV
Rv3910|M.tuberculosis_H37Rv         AGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLV
MMAR_5474|M.marinum_M               AGVALSLDHPGRVRVSIEGDVVLAYPATMPDANPQDDIRGIGAALYALLV
MUL_5063|M.ulcerans_Agy99           AGVALSLDHPGRVRVSIEGDVVLAYPATMPDANPQDDIRGIGAALYALLV
MAV_5298|M.avium_104                AGVALSIDHPSRVRVSIEGDVVLAYPATMPDANPQDDIRGIGAALYALLV
MLBr_02700|M.leprae_Br4923          AGVALSIDHPSRVRVSTEGDVVLAYPATMPDANHHTDIRGIGATLYALLV
MAB_4937|M.abscessus_ATCC_1997      AGSALSIDHPDRVRISIDGDAVLAFPATLSSASADEDVRGLGAALYALTT
                                     * ***:*** *:*:* :**..**:***:..*  . *:**:**:****  

Mvan_6064|M.vanbaalenii_PYR-1       NRWPLPETGEPSGLAPADLDAAGQPVEPRSVDRDIPFQISAAAAHAVQEG
Mflv_0842|M.gilvum_PYR-GCK          NRWPLPETGEPSGLAPAELDAAGQPAEPRSIDRDIPFQISAAAAHAVQEG
TH_2415|M.thermoresistible__bu      NRWPLPESGSPSGLAPAARDAAGEAVEPRTVDRDIPFQISAAAARAVQEG
MSMEG_6929|M.smegmatis_MC2_155      NRWPLPESGEPSGLEPAALDAAGQPVEPRAVDRDIPFQISAAAARAVQPG
Mb3940|M.bovis_AF2122/97            NRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGD
Rv3910|M.tuberculosis_H37Rv         NRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGD
MMAR_5474|M.marinum_M               NRWPLPEAGADSGFAPAERDASGNPVEPAAVDRDIPFQISAVTVRSVQED
MUL_5063|M.ulcerans_Agy99           NRWPLPEAGADSGFAPAERDASGNPVEPAAVDRDIPFQISAVTVRSVQED
MAV_5298|M.avium_104                NRWPLAESGVRSGLAPAERDSSGNPVEPMAIDRDIPFQISAVAVRAVQDD
MLBr_02700|M.leprae_Br4923          NRWPLPEAGMHSGLAPAQQDTTGQPVEPAVIDQNIPTQISAVTVRAVQED
MAB_4937|M.abscessus_ATCC_1997      RRWPLAETGQPSGLPAANRAPDGRPVEARVLIPTVPAEISDVAARALSDD
                                    .****.*:*  **: .*   . *.. *.  :   :* :** .:.:::. .

Mvan_6064|M.vanbaalenii_PYR-1       GGIRSAPTLLNLLQQATAIADRTDHIAPVDDP--------------APPP
Mflv_0842|M.gilvum_PYR-GCK          GGIRSAPTLLNLLQQATAIADRTDHISPVDEP--------------SPAA
TH_2415|M.thermoresistible__bu      GGIRSAPTLLNLLQQATAVADRTEVITTVDEG--------------DELP
MSMEG_6929|M.smegmatis_MC2_155      GGIRSAPTLLNLLQQATAIADRTELLESVEQT--------------PAAA
Mb3940|M.bovis_AF2122/97            GGIRSASTLLNLMQQATAVADRTEVLGPIDE---------------APVS
Rv3910|M.tuberculosis_H37Rv         GGIRSASTLLNLMQQATAVADRTEVLGPIDE---------------APVS
MMAR_5474|M.marinum_M               GGIRSASTLLNLLQQATAVADRTEVLGPIEP---------------PAPP
MUL_5063|M.ulcerans_Agy99           GGIRSASTLLNLLQQATAVADRTEVLGPIEP---------------PAPP
MAV_5298|M.avium_104                GGIRSASTLLNLLQQATAVADRTEVLGPIDD---------------SPSP
MLBr_02700|M.leprae_Br4923          GGILRASTLLNLLQQATAVADRTEVLSPIDDR--------------SPTP
MAB_4937|M.abscessus_ATCC_1997      PG--SAAELLDGLESAIASVDHTTMLEPAAAAPTQALDVGRRPSFEDPAD
                                     *   *. **: ::.* * .*:*  : .                      

Mvan_6064|M.vanbaalenii_PYR-1       SG-AGFAAELD--PEAAARRRKGLIVGLSVAGAIAVIAVVLLATVLSRIF
Mflv_0842|M.gilvum_PYR-GCK          VADTSWSADPEDAEEAAARRRRNLTIGLSVAGVIVVVAVILLATVLSRIF
TH_2415|M.thermoresistible__bu      PP-TRFHDAPDEDPEVQARRRKALLIGVGVGAAIIILALVVLGSILSRIF
MSMEG_6929|M.smegmatis_MC2_155      AA-----TPHTDGADAEARRRRALIVGLSAGAAIIVVALVVMATILSRIF
Mb3940|M.bovis_AF2122/97            AA---PRTSAPNS-ETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIF
Rv3910|M.tuberculosis_H37Rv         AA---PRTSAPNS-ETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIF
MMAR_5474|M.marinum_M               AP---ARSPAPTG-ATFGRRRRNLLIGIGAGAAILLVALLVLASVLNKMF
MUL_5063|M.ulcerans_Agy99           AP---ARSPAPTG-ATFGRRSRNLLIGIGAGAAILLVALLVLASVLNKMF
MAV_5298|M.avium_104                ST---ALISPGNDPATFARRRRNVLIGVGAGLAVLVAALLVLASIVSKIF
MLBr_02700|M.leprae_Br4923          TA---FCPTTARDPVVFAQRRRNLLIGIGAAVVILVVALLVMASVINKVF
MAB_4937|M.abscessus_ATCC_1997      SDDEDYEDYEEEDPEEAARHRKIFLIGLGVVGVLVISLCIALGVWVTRIF
                                                      :: : . :*:..  .: :   : :.  :.::*

Mvan_6064|M.vanbaalenii_PYR-1       GDVGDGLGGDELGLN--SPSSSTTAQP--GQSGSALKPVSVTVFSPEGEA
Mflv_0842|M.gilvum_PYR-GCK          GDVGSGLGGDELGLN--APSSSQTDSPS-TATGSALEPVRATVFSPEGEA
TH_2415|M.thermoresistible__bu      GDVGGNLNRESLGLGGTTPTASATRES--GPPGEVIKPVRATVFSPMGGA
MSMEG_6929|M.smegmatis_MC2_155      GDVGGGINRDQLGLNAPSSETESEGGDT-AAAGATVKPVRATVFSPEGEA
Mb3940|M.bovis_AF2122/97            GDVSGGLNKDELGLNAPTASTSAASS---APPGSVVKPTKVTVFSPDGGA
Rv3910|M.tuberculosis_H37Rv         GDVSGGLNKDELGLNAPTASTSAASS---APPGSVVKPTKVTVFSPDGGA
MMAR_5474|M.marinum_M               GNVGGGLDRDQLGLNAPTASTSAAASS--APAGSVVKPTKATVFSPDGEA
MUL_5063|M.ulcerans_Agy99           GNVGGGLDQDQLGLNAPTASTSAAASS--ASAGSVVKPTKATVFSPDGEA
MAV_5298|M.avium_104                GNVGGGLNKDELGLNGPSSSTSAPQTTTSAAAGSVVKPTRASVFSLDGDA
MLBr_02700|M.leprae_Br4923          GHLGSGLNNDKLGLNTPTSSTSSSPTS-SVPEGSIVKPTKATVFSPDGEA
MAB_4937|M.abscessus_ATCC_1997      GDVG-PLDKINIGIGLPTQSSGGDAAK----PGSPAKIVQATVFPPGPDA
                                    *.:.  :.  .:*:.  :  :           *   : . .:**.    *

Mvan_6064|M.vanbaalenii_PYR-1       DAPKLAGLAIDGNPATVWPIDTYTDAAPFPN-FKNGVGLMLQLPEPAKIG
Mflv_0842|M.gilvum_PYR-GCK          DAPDAASLAIDGDPSTVWPIDTYTDPVPFPN-FKNGVGLMLQLSEPARIG
TH_2415|M.thermoresistible__bu      DSPGQAGLAIDGDPSTAWPTDTYTDPVPFPN-FKNGVGLMLDLPEETEVG
MSMEG_6929|M.smegmatis_MC2_155      DNPGQAELAIDGSSSTMWSTDTYSDPVPFPG-FKNGVGLILQLPQPTVIG
Mb3940|M.bovis_AF2122/97            DNPGEADLAIDGNPATSWKTDIYTDPVPFPS-FKNGVGLMLQLPQATVVG
Rv3910|M.tuberculosis_H37Rv         DNPGEADLAIDGNPATSWKTDIYTDPVPFPS-FKNGVGLMLQLPQATVVG
MMAR_5474|M.marinum_M               DNPGQADMAIDGDSTTSWETDTYNDPVPFPG-FKNGVGLMLQLPQPTVVG
MUL_5063|M.ulcerans_Agy99           DNPGQADMAIDGDSTTSWETDTYNDPVPFPG-FKNGVGLVLQLPQPTVVG
MAV_5298|M.avium_104                DNPGTAGQAIDGDPSTAWATEVYTDAVPFPS-FKQGEGLILQLPSPTVVG
MLBr_02700|M.leprae_Br4923          DNPDDAGLAIDGNPATSWQTDIYNDAVPFPG-FKNGVGLMLHLPKPTVVS
MAB_4937|M.abscessus_ATCC_1997      DQPGKAGLAVDGNPSTSWITDTYTDADPFPVLFKPGVGLLLDLQSSSALS
                                    * *  *  *:**..:* *  : *.*. ***  ** * **:*.* . : :.

Mvan_6064|M.vanbaalenii_PYR-1       SVTVNLNSTGTSVQIRSSETATPSSLEDTTALTDPTPVKPGSNTIEVEDA
Mflv_0842|M.gilvum_PYR-GCK          SVTVNLNSTGTAVQIRSSSTATPSSLEDTTALTEPTTLKPGSNTIEVDDA
TH_2415|M.thermoresistible__bu      SVTVRLNSTGTEIQIRSADSANPSSLEDTTALTQPTRMRPGSNTIEIDNP
MSMEG_6929|M.smegmatis_MC2_155      SVDLNVTSTGTAVQLRAANSNSPSSLSDTTELTSPTTLKTGSNTISVGRA
Mb3940|M.bovis_AF2122/97            TVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPGHNTISVEAA
Rv3910|M.tuberculosis_H37Rv         TVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPGHNTISVEAA
MMAR_5474|M.marinum_M               SVTLDVPSTGTKVEIRSSPTPNPSKLDDTTVLTSATALKPGSNTIAVNAS
MUL_5063|M.ulcerans_Agy99           SVTLDVPSTGTNVEIRSSPTPNPSKLDDTTVLTSATALKPGSNTIAVNAS
MAV_5298|M.avium_104                QVSIDTPSTGTKVEIRAASSPTPAGLNDTTVLAPAFTLKPGHNVIPVRAG
MLBr_02700|M.leprae_Br4923          AVTIDVASIGTKVEIRSASTPTPAKLADTTVLIPATALKPGHNVIEVNSG
MAB_4937|M.abscessus_ATCC_1997      SVTIESHSVGTQVQIRSADSATPGSINDTKEISATATLQSGKTTIPITSS
                                     * :   * ** :::*:: : .*. : **  :  .  ::.* ..* :   

Mvan_6064|M.vanbaalenii_PYR-1       EPTSYVLVWISTLGQVDGESRSDIAEVTLNAAS-
Mflv_0842|M.gilvum_PYR-GCK          EPTSYVLVWVSTLGQVGGQSRSDIAEITLNAAS-
TH_2415|M.thermoresistible__bu      RATEHLLVWISTLGQVDGENRTDIAEITLRAPGE
MSMEG_6929|M.smegmatis_MC2_155      APTQYLLVWISTLGTVDGKSKTDISDITVKAAS-
Mb3940|M.bovis_AF2122/97            APTSNLLVWISTLGTTDGKSQADISEITIYAAS-
Rv3910|M.tuberculosis_H37Rv         APTSNLLVWISTLGTTDGKSQADISEITIYAAS-
MMAR_5474|M.marinum_M               SPTSNLLVWISTLGTTDGKSRSAISGLTIRAAS-
MUL_5063|M.ulcerans_Agy99           SPTSNLLVWISTLGTTDGKSRSAISQLTIRAAS-
MAV_5298|M.avium_104                SPTSNLLVWISTLGTTNGKSQAGFSEITVQAAS-
MLBr_02700|M.leprae_Br4923          SPMSNLLVWISTLGSTGGKSLAVISEITIHTPS-
MAB_4937|M.abscessus_ATCC_1997      SQVSHVLVWINKLGSTNGDHHAEISEITVSTAS-
                                       . :***:..** ..*.  : :: :*: :..