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VPYGQAAAGPPKRAELSDAALVSRSWGMALATLVSRITGFARIVLLAAILGAALSSSFSVANQLPNLVAA LVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLTTTLLIVATTLSVLAAPLLVRLMLGRDPQVNEPL TTAFAYLLLPQVLVYGLSSVFMAILNTRNVFGPPAWAPVINNVVAIATLLVYLAVPGELAIDPVKMGNAK LLVLGVGTTLGVFAQAAVLLVAIGRQHISLRPLWGIDDRLKRFGAMAAAMVLYVLISQLGLIVGNQIASG AAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAAEDIPAVLADLSLATRLTMITLIPTVAFMT VGGSAMGSALFAYGNFGKVDAGYLGAAIALSAFTLIPYALVLLGLRVFYAREQPWTPILIIIIITSVKIG ASVLAPHLTNDPDMVAGYLGLANGLGFLAGAIVGYYLLRRALRPGGGQLVGTREVHTILVTIAASLLAGL LAYVVDRLAGLGQLTVFGGGIGSLLRLLILGVIMAPIVIAVLLAGQVPEAQAALNVVRNRIGTRLGKPGP RSVAVPDASSGDHDVTYPEQRKSSLPGENVVQEPIRRKPPVIRAGIAKGPSVTDRPSDSTASSSSASDID LPRPVADDFQPDIPAGPDRGRGASQRPSDQSNGDSVGYTRGPIPFDAPRERSAEPSTPQDDVNLVPGARI ANGRYRLLVFHGGIPPLQFWQALDTALDRQVALTFVDPDGTLPEDVLQEILARTLRLSRIDKPGVARVLD VLHTASGGLVVSEWIRGGSLQEVADTAPSPVGAIRAMQSLAAAADAAHRAGVALSLDHPGRVRVSIEGDV VLAYPATMPDANPQDDIRGIGAALYALLVNRWPLPEAGADSGFAPAERDASGNPVEPAAVDRDIPFQISA VTVRSVQEDGGIRSASTLLNLLQQATAVADRTEVLGPIEPPAPPAPARSPAPTGATFGRRRRNLLIGIGA GAAILLVALLVLASVLNKMFGNVGGGLDRDQLGLNAPTASTSAAASSAPAGSVVKPTKATVFSPDGEADN PGQADMAIDGDSTTSWETDTYNDPVPFPGFKNGVGLMLQLPQPTVVGSVTLDVPSTGTKVEIRSSPTPNP SKLDDTTVLTSATALKPGSNTIAVNASSPTSNLLVWISTLGTTDGKSRSAISGLTIRAAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5474 | - | - | 100% (1180) | transmembrane protein |
| M. marinum M | MMAR_2941 | - | 3e-47 | 44.49% (236) | membrane-anchored serine/threonine-protein kinase |
| M. marinum M | MMAR_3211 | pknL | 2e-09 | 23.81% (315) | transmembrane serine/threonine-protein kinase L PknL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3940 | - | 0.0 | 79.09% (1181) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0842 | - | 0.0 | 63.08% (1216) | integral membrane protein MviN |
| M. tuberculosis H37Rv | Rv3910 | - | 0.0 | 79.09% (1181) | transmembrane protein |
| M. leprae Br4923 | MLBr_02700 | - | 0.0 | 73.54% (1179) | hypothetical protein MLBr_02700 |
| M. abscessus ATCC 19977 | MAB_4937 | - | 0.0 | 51.51% (1190) | hypothetical protein MAB_4937 |
| M. avium 104 | MAV_5298 | - | 0.0 | 77.47% (1176) | virulence factor mvin family protein |
| M. smegmatis MC2 155 | MSMEG_6929 | - | 0.0 | 69.50% (1210) | integral membrane protein MviN, putative |
| M. thermoresistible (build 8) | TH_2416 | - | 0.0 | 77.42% (496) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_5063 | - | 0.0 | 98.22% (1180) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_6064 | - | 0.0 | 65.65% (1208) | integral membrane protein MviN |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0842|M.gilvum_PYR-GCK ---------------------------------------MPDARPEMSDR
Mvan_6064|M.vanbaalenii_PYR-1 ------------MRDAAPRRAPTRRPRSSPPPPPPPPRRPQAARPEMSDA
MSMEG_6929|M.smegmatis_MC2_155 ------------MNATQPQRPPGPRRLPRGPAP-----RRRAGQEELSDA
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M ---------------------------MPYGQAAAGPP----KRAELSDA
MUL_5063|M.ulcerans_Agy99 ---------------------------MPYGPAAAGPP----KRAELSDA
Mb3940|M.bovis_AF2122/97 -------------------------MRPSPGEVPTASQ----RQPELSDA
Rv3910|M.tuberculosis_H37Rv -------------------------MRPSPGEVPTASQ----RQPELSDA
MAV_5298|M.avium_104 MNPAYRQAAPHHRRLPEPPRRPRMPGSPPTGPLPPVPAGIDRRRPELSDS
MLBr_02700|M.leprae_Br4923 --------------MKPAPRWTQSQSAQQVTHAMRPCRELSAQQPELSDA
MAB_4937|M.abscessus_ATCC_1997 ---------------------------MREPLDPLPDPEADDTIEELSDA
Mflv_0842|M.gilvum_PYR-GCK AVVSRSWGMAVATLVSRLTGFARIVLLAAILGAALSSAFTVANQLPNMIA
Mvan_6064|M.vanbaalenii_PYR-1 AVVSRSWGMALATLVSRLTGFARIVLLAAILGAALSSAFTVANQLPNMIA
MSMEG_6929|M.smegmatis_MC2_155 AVVSRSWGMAMATLISRITGFIRIVLLAAILGAALSSAFSVANQLPNLIA
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M ALVSRSWGMALATLVSRITGFARIVLLAAILGAALSSSFSVANQLPNLVA
MUL_5063|M.ulcerans_Agy99 ALVSRSWGMALATLVSRITGFARIVLLAAILGAALSSSFSVANQLPNLVA
Mb3940|M.bovis_AF2122/97 ALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVA
Rv3910|M.tuberculosis_H37Rv ALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVA
MAV_5298|M.avium_104 ALVSRSWAMAFATLVSRLTGFARVVLLAAILGAALSSAFSVANQLPNLVA
MLBr_02700|M.leprae_Br4923 ALVSRSWAMAFATLISRITGFARVVLLAAILGAALSSAFSVANQLPNLVA
MAB_4937|M.abscessus_ATCC_1997 AVVSHSGSMAVATLVSRITGFIKLLLITAALGAASASAFSTANTLPNIIA
Mflv_0842|M.gilvum_PYR-GCK ALVLEATFTAIFVPVLARAERDDPDGGAAFIRRLLTLATALLLAVTIIST
Mvan_6064|M.vanbaalenii_PYR-1 ALVLEATFTAIFVPVLARAERDDPDGGAAFIRRLLTLATTLLLVVTIIST
MSMEG_6929|M.smegmatis_MC2_155 ALVLEATFTAIFVPVLARAERDDPDGGAAFVRRLVTLVTTLLLVTTLVSV
TH_2416|M.thermoresistible__bu --VLEATFTAIFVPVLARAERDDPDGGTAFIRRLVTLATTLLLVTTLISV
MMAR_5474|M.marinum_M ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLTTTLLIVATTLSV
MUL_5063|M.ulcerans_Agy99 ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLTTALLIVATTLSV
Mb3940|M.bovis_AF2122/97 ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSV
Rv3910|M.tuberculosis_H37Rv ALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSV
MAV_5298|M.avium_104 ALVLEATFTAIFVPVLARAEQSDPDGGAAFVRRLVTLTTALLIVATALSV
MLBr_02700|M.leprae_Br4923 ALVLEATFTAIFVPVLVRAERSDPDGGTAFVRQLITLTTTLLLLSTTLSV
MAB_4937|M.abscessus_ATCC_1997 ALVLEATFTAIFIPVLTRAEREDADGGEAFIRKLLTIVTTLLLVTTLLSV
**********:***.***:.*.*** **:*:*:*:.*:**: * :*.
Mflv_0842|M.gilvum_PYR-GCK VGAPLLVNLMLGSEPLVNQPLTTAFAFLLLPQIIFYGLSSVFMAILNTRN
Mvan_6064|M.vanbaalenii_PYR-1 VAAPLLVDLMLGPDPLVDRPLTTAFAYLLLPQIIFYGLSSVFMAILNTRN
MSMEG_6929|M.smegmatis_MC2_155 AAAPALVRLMLGDDPQVNEPLTTAFAYLLLPQVLFYGLSSVFMAILNTRN
TH_2416|M.thermoresistible__bu AAAPALTRLMLGGDPQVNEPLTTAFAYLLLPQVLFYGLSSVFMAILNTRN
MMAR_5474|M.marinum_M LAAPLLVRLMLGRDPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
MUL_5063|M.ulcerans_Agy99 LAAPLLVRLMLGRDPQVNEPLTTAFAYLLLPQVLVYGLSSVFIAILNTRN
Mb3940|M.bovis_AF2122/97 LAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
Rv3910|M.tuberculosis_H37Rv LAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRN
MAV_5298|M.avium_104 AAAPLLVRLMLGRTPQVNEPLTVAFAYLLLPQVLAYGLTSVFMAILNTRN
MLBr_02700|M.leprae_Br4923 LAAPLLVRLMLGRNPQVNEPLTTAFAYLLLPQVLAYGLSSVFMAILNTRN
MAB_4937|M.abscessus_ATCC_1997 LAAPLLAGIMLGGDPKVNTPLTTALAYLLLPQVFFYGLSSLFMAILNTRN
.** *. :*** * *: ***.*:*:*****:: ***:*:*:*******
Mflv_0842|M.gilvum_PYR-GCK IFGPPAWAPVVNNVVAIATLGLYVLVPGELSLDPVRMGDAKLLVLGIGTT
Mvan_6064|M.vanbaalenii_PYR-1 VFGPPAWAPVVNNVVAILTLGLYVLVPGELSLNPVQMGDAKLLVLGVGTT
MSMEG_6929|M.smegmatis_MC2_155 VFGPPAWAPVLNNVVAIATLGAYLLVPGELSVDPVQMGNAKLLVLGVGTT
TH_2416|M.thermoresistible__bu VFGPPAWAPVVNNVVAIATLGLYLLVPGELSVDPVEMGNAKLLVLGIGTT
MMAR_5474|M.marinum_M VFGPPAWAPVINNVVAIATLLVYLAVPGELAIDPVKMGNAKLLVLGVGTT
MUL_5063|M.ulcerans_Agy99 VFGPPAWAPVINNGVAIATLLVYLAVPGELAVDPVKMGNAKLLVLGVGTT
Mb3940|M.bovis_AF2122/97 VFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTT
Rv3910|M.tuberculosis_H37Rv VFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTT
MAV_5298|M.avium_104 VFGPTAWAPVVNNVVALATLAVYALVPGELSVDPVRMGNAKLLVLAVGTT
MLBr_02700|M.leprae_Br4923 VFGPPAWAPVINNIVAIAALVGYLVTPGELSVDPVRMGNAKLLVLGIGTT
MAB_4937|M.abscessus_ATCC_1997 VFGPPAWAPVWNNLVAIATLVLYWLMPGELTLDPIRMSDPKLLVLGIGTT
:***.***** ** **: :* * ****:::*:.*.:.*****.:***
Mflv_0842|M.gilvum_PYR-GCK LGVVAQAAVLFVAIRRERISLRPLWGIDARLKKFGMMALAMVLYVLVSQV
Mvan_6064|M.vanbaalenii_PYR-1 LGVVAQAGVLFMAIRRQRVSLRPLWGIDARLKKFGMMAVAMVLYVLISQV
MSMEG_6929|M.smegmatis_MC2_155 LGVVAQCSVLLPAIRRERISLRPLWGIDDRLKKFGAMAAAMVLYVLISQI
TH_2416|M.thermoresistible__bu LGVVAQCGVLVVAIRRERISLRPLWGIDDRLKRFGTMAAAMVLYVLISQI
MMAR_5474|M.marinum_M LGVFAQAAVLLVAIGRQHISLRPLWGIDDRLKRFGAMAAAMVLYVLISQL
MUL_5063|M.ulcerans_Agy99 LGVFAQAAVLLVAIGRQHISLRPLWGIDDRLKRFGAMAAAMVLYVLVSQL
Mb3940|M.bovis_AF2122/97 AGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQL
Rv3910|M.tuberculosis_H37Rv AGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQL
MAV_5298|M.avium_104 LGVFAQTGVLLVALRRQHVDLRPLWGIDQRLKRFGTLAAAMVLYVLISQL
MLBr_02700|M.leprae_Br4923 AGAFAQTAVLLVALGREHISLHPLWGLDQRLKRFGAMATAMVLYVLISQL
MAB_4937|M.abscessus_ATCC_1997 LGVAAQAMVLLPAIRRQQIPLRPLWGLDDRLKQFGGMAAAMFAYVAISQF
*. ** **. *: *::: *:****:* ***:** :* **. ** :**.
Mflv_0842|M.gilvum_PYR-GCK GFIVGNQVASASAASGPAIYNYTWLILQLPFGIVGVTVLTVVMPRLSRNA
Mvan_6064|M.vanbaalenii_PYR-1 GFIVGNQVASTAAASGPAIYNYTWLILQLPFGIVGVTVLTVVMPRLSRNA
MSMEG_6929|M.smegmatis_MC2_155 GLVVGNQIASGAAASGPAIYNYAWLVLQLPFGMIGVTVLTVVMPRLSRNA
TH_2416|M.thermoresistible__bu GLVVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MMAR_5474|M.marinum_M GLIVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MUL_5063|M.ulcerans_Agy99 GLIVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
Mb3940|M.bovis_AF2122/97 GLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
Rv3910|M.tuberculosis_H37Rv GLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MAV_5298|M.avium_104 GLVVGNQIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNA
MLBr_02700|M.leprae_Br4923 GLVVTNQIASTTAASGPAIYNYTWLVLMLPFGIIGVTVLTVVMPRLSRNA
MAB_4937|M.abscessus_ATCC_1997 GYVIANRIAAGAAESGPIIYSQTWMILQLPYGVVGVTILTAIMPRLSRNA
* :: *::*: :* *** **. :*::* **:*::***:**.:********
Mflv_0842|M.gilvum_PYR-GCK ASGDGGAVLADLSLATRLTMLTLIPIVALMTVGGPAIGSALFSYGNFGAV
Mvan_6064|M.vanbaalenii_PYR-1 AADDAPAVLADLSLATRLTMITLIPIVAMMTVGGPAIGSALFSYGNFGAV
MSMEG_6929|M.smegmatis_MC2_155 AKNDIPAVLGDLSLATRLTMITLIPIVALMTVGGPAIGTALFAYGNFGRV
TH_2416|M.thermoresistible__bu AAEDVPAVLRDFALAIRLTMVTLIPIVAVMTVGGPAIGTALFAYGNFGSV
MMAR_5474|M.marinum_M AAEDIPAVLADLSLATRLTMITLIPTVAFMTVGGSAMGSALFAYGNFGKV
MUL_5063|M.ulcerans_Agy99 AAEDILAVLADLSLATRLTMITLIPTVAFMTVGGSAMGSALFAYGNFGKV
Mb3940|M.bovis_AF2122/97 AADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDV
Rv3910|M.tuberculosis_H37Rv AADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDV
MAV_5298|M.avium_104 AADDTRAVLADLSLATRLTLITLIPIVAFMTVGGPAMGSALFAYGHFGDV
MLBr_02700|M.leprae_Br4923 AANDTPAMLADLSLATRLTLITLIPTVAFMTAGGSAMGSVLFAYGHFGEV
MAB_4937|M.abscessus_ATCC_1997 AAQDTPAVLGDMSLATRLTMTVLIPVVAVMTVAGPAMGPALFAYGNFHLG
* * *:* *::** ***: .*** **.**..*.*:*..**:**:*
Mflv_0842|M.gilvum_PYR-GCK DAGYLGMAITLSAFTLIPYTMVLLQLRVFYAREEPWTPIVLIVVITIVKI
Mvan_6064|M.vanbaalenii_PYR-1 DAGYLGMAITLSAFTLIPYTLVLLQLRVFYAREEPWTPILLIIVITIVKI
MSMEG_6929|M.smegmatis_MC2_155 DAGYLGLAISLSAFTLIPYALVLLQLRVFYARERAWTPIIVIIVITVVKI
TH_2416|M.thermoresistible__bu DAGYLGMAITLSAFTLIPYALVLLQLRVFYARERPWTPIIVIVVITAVKI
MMAR_5474|M.marinum_M DAGYLGAAIALSAFTLIPYALVLLGLRVFYAREQPWTPILIIIIITSVKI
MUL_5063|M.ulcerans_Agy99 DAGYLGAAIALSAFTLIPYALVLLGLRVFYAREQPWTPILIIIIITSVKI
Mb3940|M.bovis_AF2122/97 DAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKI
Rv3910|M.tuberculosis_H37Rv DAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKI
MAV_5298|M.avium_104 DAGYLGAAIALSAFTLIPYGLVLLQLRVFYAREQPWTPIVIILVITAVKI
MLBr_02700|M.leprae_Br4923 DAGYLGTAIVLSAFTLIPYGLVLLQLRVFYAREQPWTPIVIIVVITAVRI
MAB_4937|M.abscessus_ATCC_1997 SAHYLGLSISLSAFTLIPYALVLLQLRVFYARHEAWTPTLMIIVITAVKV
.* *** :* ********* :*** *******...*** :*::** *::
Mflv_0842|M.gilvum_PYR-GCK AASLASPHLTDDPQLVAGYLGLANGLGFLAGATVGYLLLRARLDPPGGHL
Mvan_6064|M.vanbaalenii_PYR-1 AASLAAPHLTADPQLVAGYLGLANGLGFLAGATVGYLLLRARLDPPGGRL
MSMEG_6929|M.smegmatis_MC2_155 AGSVAAPHLTNNPEMVAGYLGAANGLGFMAGAIVGHVLLRANLDPPGGRL
TH_2416|M.thermoresistible__bu AASVAAPHLTSDPDLVAGYLGLANGLGFAAGAVVGHLLLRAHLDPPGGRL
MMAR_5474|M.marinum_M GASVLAPHLTNDPDMVAGYLGLANGLGFLAGAIVGYYLLRRALRPGGGQL
MUL_5063|M.ulcerans_Agy99 GASVLAPHLTNDPDMVAGYLGLANGLGFLAGAIVGYYLLRRALCPGGGQL
Mb3940|M.bovis_AF2122/97 LGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQL
Rv3910|M.tuberculosis_H37Rv LGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQL
MAV_5298|M.avium_104 LGSVLAPHLTGDPKLVAGFLGLANGVGFLAGAVIGYVLLRRTLLPGGGHL
MLBr_02700|M.leprae_Br4923 IVSVLAPYVISNPELVAGYLGMANGLGFAAGAIVGYYLLRRALLPTGGHL
MAB_4937|M.abscessus_ATCC_1997 IGSVAAPHLTDDPDLVAGYLGAANGLGFVAGALCGYLLLRRSLGRAAGPL
*: :*:: :*.:**.:** ***:** **: *: :** * .* *
Mflv_0842|M.gilvum_PYR-GCK VSRDVVRTILVTITASLAAGLIAHIADQILGLEQLTEHWGGGGSLIRLAV
Mvan_6064|M.vanbaalenii_PYR-1 LDNAVIRTILVTITASLAAGLTAHVVDQLAGLENLTTHWGAAGSLLRLLA
MSMEG_6929|M.smegmatis_MC2_155 VSLTVVRTILVTITASLLAVLVSVVVDQLLGVEQLTVRFGAGGSMIRLVV
TH_2416|M.thermoresistible__bu LEPAVVRTVLVTIAASLTAALIGQIADQLLGLEQLTANGGGAGSLLRLLV
MMAR_5474|M.marinum_M VGTREVHTILVTIAASLLAGLLAYVVDRLAGLGQLTVFGGGIGSLLRLLI
MUL_5063|M.ulcerans_Agy99 VGTREVHTILVTIAASLLAGLLAYVVDRLAGLGQLTVFDGGIGSLLRLLI
Mb3940|M.bovis_AF2122/97 IGVGEARTALVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSV
Rv3910|M.tuberculosis_H37Rv IGVGEARTVLVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSV
MAV_5298|M.avium_104 IGVGEVRTILVTLTAAMLAGLVAHVADRLLGLSALTAHGGGAGSLLRLLV
MLBr_02700|M.leprae_Br4923 FGVQEIRTVLVTIAASLLAGLAAHIADRLLRLNELTMHGGGAGSLLRLTV
MAB_4937|M.abscessus_ATCC_1997 IGPDVARTALVALAASVTAAAVGLGIDRGFGLDLLTQRGGGLGSILRLAI
. :* **:::*:: * . *: : ** *. **::**
Mflv_0842|M.gilvum_PYR-GCK LGLVMGPIILGVLIAAKVPDALAGVAAVRRRLGARG--------------
Mvan_6064|M.vanbaalenii_PYR-1 LGLVMVPIIAAVMLTAKVPEAQAALAAVRRRLGTRG--------------
MSMEG_6929|M.smegmatis_MC2_155 LGLIMLPIIAGVLIAAKVPEAQAAIRVVRGRLGRFGGKETPAVDAAEKVA
TH_2416|M.thermoresistible__bu LGLIMAPVIAAFLWFARVPEAEAAVAAVRRRFGKTP--------------
MMAR_5474|M.marinum_M LGVIMAPIVIAVLLAGQVPEAQAALNVVRNRIGTRLGKPGPR--------
MUL_5063|M.ulcerans_Agy99 LGVIMAPIVIAVLLAGQVPEAQAALNVVRNRIGTRLGKPGPR--------
Mb3940|M.bovis_AF2122/97 LALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQ--------
Rv3910|M.tuberculosis_H37Rv LALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQ--------
MAV_5298|M.avium_104 LALIMVPITAAVMLRAQVPEARAALDAVRFRITGR--GPRPR--------
MLBr_02700|M.leprae_Br4923 LTSIMLPTMAVVMLRGHVPEVHAALGAVRGQIMSRNWIAKLQ--------
MAB_4937|M.abscessus_ATCC_1997 LGIVMLAVTFALMVAVKLPEALSVVAMLQRRLGGRLG-------------
* :* . . ::*:. : : :: ::
Mflv_0842|M.gilvum_PYR-GCK -ATTGSPVPQMSPRALTYADRSNR--------------RGPSAETADDGR
Mvan_6064|M.vanbaalenii_PYR-1 -PAAEPSVRPRPSDTLTYPDHKNRSSL-RRRQLPRSAARGPSAEAADDGR
MSMEG_6929|M.smegmatis_MC2_155 LQTNGPAVPPRTAGAVTYPDQRNSSPG-RGPTTPAPGWVGAPASVAGAGT
TH_2416|M.thermoresistible__bu -------------------------------------ASGPAPVTAGDRR
MMAR_5474|M.marinum_M --SVAVPDASSGDHDVTYPEQRKSSLP-GENVVQEPIRRKPP--VIRAGI
MUL_5063|M.ulcerans_Agy99 --SVAVLDPSSGDHDVTYPEQRKSSLP-GENVVQEPIRRKPP--VIRAGI
Mb3940|M.bovis_AF2122/97 --TQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRRRPPEQVARAGR
Rv3910|M.tuberculosis_H37Rv --TQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRRRPPEQVARAGR
MAV_5298|M.avium_104 --KPAAPDRSSHRRPVTYPEQRNSSPP-GVNAVQEPIRRRPPERANRARL
MLBr_02700|M.leprae_Br4923 --KATVPDQSSRPITVTYPGQNNSSPP-RVNAIQESIRSRPPERIAKAQI
MAB_4937|M.abscessus_ATCC_1997 ----------------------------------ARLRAETQDHASVMGN
.
Mflv_0842|M.gilvum_PYR-GCK RKGSAVSDKPTSDSPSGPDSTAPPSGPNSTAPPSGPNSTAPPSGPNSTAP
Mvan_6064|M.vanbaalenii_PYR-1 RKGFAVSDKPTSGSPGGPDSAATTR----------------------ITR
MSMEG_6929|M.smegmatis_MC2_155 RKGSPVTDESAGG--PALDGTATTK----------------------LPR
TH_2416|M.thermoresistible__bu CTG-----------------------------------------------
MMAR_5474|M.marinum_M AKGPSVTDRPSDSTASSS-SASDI----------------------DLPR
MUL_5063|M.ulcerans_Agy99 AKGPSVTDRPSDSTASSS-SASDI----------------------DLPR
Mb3940|M.bovis_AF2122/97 AKGPEVIDRPSE-NASFG-AASGA----------------------ELPR
Rv3910|M.tuberculosis_H37Rv AKGPEVIDRPSE-NASFG-AASGA----------------------ELPR
MAV_5298|M.avium_104 VKGPEVTDRPMESAASSAGPGTGS----------------------GAPR
MLBr_02700|M.leprae_Br4923 AKGPEVSDRPVESASSRSASDTGLP--------------------SELPR
MAB_4937|M.abscessus_ATCC_1997 SPGPSLPYPDSGDPVGGSDAIGST-----------------------TAN
*
Mflv_0842|M.gilvum_PYR-GCK PSADDFQPDVPDSYQPDPAADDSATTALP-AQGVPTQSPSKSPTETPTEA
Mvan_6064|M.vanbaalenii_PYR-1 PSPDDFQPDVPEDAGTHVLPQAPARPTGPESAARPTGPESAARPAGPESA
MSMEG_6929|M.smegmatis_MC2_155 QAPDDFQPDVADDES----EAAGAEPTVEETVSLPNGS------------
TH_2416|M.thermoresistible__bu --AD----------------------------------------------
MMAR_5474|M.marinum_M PVADDFQPDIPAG--PDRGRGASQRPS-----------------------
MUL_5063|M.ulcerans_Agy99 PVADDFQPDIPAG--PDRGRGASLRPS-----------------------
Mb3940|M.bovis_AF2122/97 PVADELQLDAPAG--RDPGPVSRPHPS-----------------------
Rv3910|M.tuberculosis_H37Rv PVADELQLDAPAG--RDPGPVSRPHPS-----------------------
MAV_5298|M.avium_104 PVADDFQPDIPADQ-PDRPRKADPRPA-----------------------
MLBr_02700|M.leprae_Br4923 PVAGNSQPYISAN--LELEHVASLHPP-----------------------
MAB_4937|M.abscessus_ATCC_1997 KPAHGGGADTRKG-------------------------------------
.
Mflv_0842|M.gilvum_PYR-GCK VKRPRADYSNDPTREALAFDPPREPAIETATPAEDTHLIPGATIAGGRYR
Mvan_6064|M.vanbaalenii_PYR-1 ARPPVSDYAGDPTREALPFDPPREPATEAATTAEDMHLIPGATIVDGRYR
MSMEG_6929|M.smegmatis_MC2_155 -GRPPADYGGDPTREPISFAPPREPAVESATSGDDVHLIPGATIADGRYR
TH_2416|M.thermoresistible__bu -SQPGGDYRG------------RIPARSAFP-------VP----------
MMAR_5474|M.marinum_M -DQSNGDS-VGYTRGPIPFDAPRERSAEPSTPQDDVNLVPGARIANGRYR
MUL_5063|M.ulcerans_Agy99 -DLSNGDS-VGYTRGPIPFDAPRECSAEPSTPQDDVNLVPGARIANGRYR
Mb3940|M.bovis_AF2122/97 -DLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYR
Rv3910|M.tuberculosis_H37Rv -DLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYR
MAV_5298|M.avium_104 -DQKNGDA--GTRRG--PFDVPRERAADSSA--DDVHLVPGARIAGGRYR
MLBr_02700|M.leprae_Br4923 -EQQKVDFPAYPARRPIRFEVSRERGGEQSSPTGDVHLVPGACIAGGRYR
MAB_4937|M.abscessus_ATCC_1997 --RAVTDTPGSSTRP--------VPTQSPSTGPVPTSVMPGASIAGGRYR
* . . :*
Mflv_0842|M.gilvum_PYR-GCK LLVSHGGPEHLQFWQATDTALDRQVALTFVAPDATMPDQQVQGILDRTQR
Mvan_6064|M.vanbaalenii_PYR-1 LLVSHGGPAHLQFWQALDTALDRQVALTFVDPDATMPDRAVQEILDRTQR
MSMEG_6929|M.smegmatis_MC2_155 LLVFHGGPPHLQFWQALDTALDRQVALTFVDPDAKLPDSQVQDILSRTLK
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M LLVFHGGIPPLQFWQALDTALDRQVALTFVDPDGTLPEDVLQEILARTLR
MUL_5063|M.ulcerans_Agy99 LLVFHGGIPPLQFWQALDTALDRQVALTFVDPDGTLPEDVLQEILARTLR
Mb3940|M.bovis_AF2122/97 LLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLR
Rv3910|M.tuberculosis_H37Rv LLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLR
MAV_5298|M.avium_104 LLVFHGGAPPLQFWQALDTALDRQVALTFVDPDRALPDEVLQEILSRTLR
MLBr_02700|M.leprae_Br4923 LLAFHGGAPSLQFWQALDTALDRQVALTFVNPDGALPDDSLQETLSRTLR
MAB_4937|M.abscessus_ATCC_1997 LLTSHGGPDGLQFWQATDTELNRPVALTIIDG-AAFTADQVQDILSNTLR
Mflv_0842|M.gilvum_PYR-GCK LSQIDMPGVARVLDVLKTATGGLVVSEWIRGGSLAEVAATNPSPIGGARA
Mvan_6064|M.vanbaalenii_PYR-1 LSRIDMPGVARVLDVVSTGVGGLVVSEWIRGGSLAEVADTCPSPIGGARA
MSMEG_6929|M.smegmatis_MC2_155 LSRLDVPGIARVLDVAHSGSGGLIVSEWIRGGSLAEVADTAPSPIGGARA
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M LSRIDKPGVARVLDVLHTASGGLVVSEWIRGGSLQEVADTAPSPVGAIRA
MUL_5063|M.ulcerans_Agy99 LSRIDKPGVARVLDVLHTASGGLVVSEWIRGGSLQEVADTAPSPVGAIRA
Mb3940|M.bovis_AF2122/97 LSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRA
Rv3910|M.tuberculosis_H37Rv LSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRA
MAV_5298|M.avium_104 LSRIDKPGIARVLDVVHTGSGGLVVSEWIRGGSLQEVADTAPSPVGAVRA
MLBr_02700|M.leprae_Br4923 LSRIDMPGVAQVLDVIHTGSGGLVVSEWIRGGSLHEVADTSPSPVGAIRA
MAB_4937|M.abscessus_ATCC_1997 LSKIESSGLARVLDAVHEGNGGIVVAQWVRGGSLREVADTEPSAVGASRA
Mflv_0842|M.gilvum_PYR-GCK IQSLAAAAEVAHRNGVALSIDHPSRIRVSIDGDVALAFPATLPDATPDDD
Mvan_6064|M.vanbaalenii_PYR-1 IQSLAAAAEVAHRNGVALSIDHPSRIRVSIDGDVALAFPATLPDASPDDD
MSMEG_6929|M.smegmatis_MC2_155 IQSLAAAAEAAHRAGVALSIDHPSRVRVSIEGDVALAFPATLPDATPDDD
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M MQSLAAAADAAHRAGVALSLDHPGRVRVSIEGDVVLAYPATMPDANPQDD
MUL_5063|M.ulcerans_Agy99 IQSLAAAADAAHRAGVALSLDHPGRVRVSIEGDVVLAYPATMPDANPQDD
Mb3940|M.bovis_AF2122/97 MQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDD
Rv3910|M.tuberculosis_H37Rv MQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDD
MAV_5298|M.avium_104 MQSLAAAADAAHRAGVALSIDHPSRVRVSIEGDVVLAYPATMPDANPQDD
MLBr_02700|M.leprae_Br4923 MQSLAAAADAAHRAGVALSIDHPSRVRVSTEGDVVLAYPATMPDANHHTD
MAB_4937|M.abscessus_ATCC_1997 VRSLAEAADAAFEAGSALSIDHPDRVRISIDGDAVLAFPATLSSASADED
Mflv_0842|M.gilvum_PYR-GCK IRGIGASLYALLINRWPLPETGEPSGLAPAELDAAGQPAEPRSIDRDIPF
Mvan_6064|M.vanbaalenii_PYR-1 IRGIGASLYALLVNRWPLPETGEPSGLAPADLDAAGQPVEPRSVDRDIPF
MSMEG_6929|M.smegmatis_MC2_155 IRGIGAALYALLVNRWPLPESGEPSGLEPAALDAAGQPVEPRAVDRDIPF
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M IRGIGAALYALLVNRWPLPEAGADSGFAPAERDASGNPVEPAAVDRDIPF
MUL_5063|M.ulcerans_Agy99 IRGIGAALYALLVNRWPLPEAGADSGFAPAERDASGNPVEPAAVDRDIPF
Mb3940|M.bovis_AF2122/97 IRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPF
Rv3910|M.tuberculosis_H37Rv IRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPF
MAV_5298|M.avium_104 IRGIGAALYALLVNRWPLAESGVRSGLAPAERDSSGNPVEPMAIDRDIPF
MLBr_02700|M.leprae_Br4923 IRGIGATLYALLVNRWPLPEAGMHSGLAPAQQDTTGQPVEPAVIDQNIPT
MAB_4937|M.abscessus_ATCC_1997 VRGLGAALYALTTRRWPLAETGQPSGLPAANRAPDGRPVEARVLIPTVPA
Mflv_0842|M.gilvum_PYR-GCK QISAAAAHAVQEGGGIRSAPTLLNLLQQATAIADRTDHISPVDEP-----
Mvan_6064|M.vanbaalenii_PYR-1 QISAAAAHAVQEGGGIRSAPTLLNLLQQATAIADRTDHIAPVDDP-----
MSMEG_6929|M.smegmatis_MC2_155 QISAAAARAVQPGGGIRSAPTLLNLLQQATAIADRTELLESVEQT-----
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M QISAVTVRSVQEDGGIRSASTLLNLLQQATAVADRTEVLGPIEP------
MUL_5063|M.ulcerans_Agy99 QISAVTVRSVQEDGGIRSASTLLNLLQQATAVADRTEVLGPIEP------
Mb3940|M.bovis_AF2122/97 QISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDE------
Rv3910|M.tuberculosis_H37Rv QISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDE------
MAV_5298|M.avium_104 QISAVAVRAVQDDGGIRSASTLLNLLQQATAVADRTEVLGPIDD------
MLBr_02700|M.leprae_Br4923 QISAVTVRAVQEDGGILRASTLLNLLQQATAVADRTEVLSPIDDR-----
MAB_4937|M.abscessus_ATCC_1997 EISDVAARALSDDPG--SAAELLDGLESAIASVDHTTMLEPAAAAPTQAL
Mflv_0842|M.gilvum_PYR-GCK ---------SPAAVADTSWSADPEDAEEAAARRRRNLTIGLSVAGVIVVV
Mvan_6064|M.vanbaalenii_PYR-1 ---------APPPSG-AGFAAELD--PEAAARRRKGLIVGLSVAGAIAVI
MSMEG_6929|M.smegmatis_MC2_155 ----------PAAAAATPHTDGAD----AEARRRRALIVGLSAGAAIIVV
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M ---------PAPPAPARSPAPTG----ATFGRRRRNLLIGIGAGAAILLV
MUL_5063|M.ulcerans_Agy99 ---------PAPPAPARSPAPTG----ATFGRRSRNLLIGIGAGAAILLV
Mb3940|M.bovis_AF2122/97 ---------APVSAAPRTSAPNS----ETYTRRRRNLLIGIGAGAAVLMV
Rv3910|M.tuberculosis_H37Rv ---------APVSAAPRTSAPNS----ETYTRRRRNLLIGIGAGAAVLMV
MAV_5298|M.avium_104 ---------SPSPSTALISPGNDP---ATFARRRRNVLIGVGAGLAVLVA
MLBr_02700|M.leprae_Br4923 ---------SPTPTAFCPTTARDP---VVFAQRRRNLLIGIGAAVVILVV
MAB_4937|M.abscessus_ATCC_1997 DVGRRPSFEDPADSDDEDYEDYEEEDPEEAARHRKIFLIGLGVVGVLVIS
Mflv_0842|M.gilvum_PYR-GCK AVILLATVLSRIFGDVGSGLGGDELGLNAPSSSQTDSPS---TATGSALE
Mvan_6064|M.vanbaalenii_PYR-1 AVVLLATVLSRIFGDVGDGLGGDELGLNSPSSSTTAQP----GQSGSALK
MSMEG_6929|M.smegmatis_MC2_155 ALVVMATILSRIFGDVGGGINRDQLGLNAPSSETESEGGD-TAAAGATVK
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M ALLVLASVLNKMFGNVGGGLDRDQLGLNAPTASTSAAASS--APAGSVVK
MUL_5063|M.ulcerans_Agy99 ALLVLASVLNKMFGNVGGGLDQDQLGLNAPTASTSAAASS--ASAGSVVK
Mb3940|M.bovis_AF2122/97 ALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASS---APPGSVVK
Rv3910|M.tuberculosis_H37Rv ALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASS---APPGSVVK
MAV_5298|M.avium_104 ALLVLASIVSKIFGNVGGGLNKDELGLNGPSSSTSAPQTTTSAAAGSVVK
MLBr_02700|M.leprae_Br4923 ALLVMASVINKVFGHLGSGLNNDKLGLNTPTSSTSSSPTS-SVPEGSIVK
MAB_4937|M.abscessus_ATCC_1997 LCIALGVWVTRIFGDVGP-LDKINIGIGLPTQSSGGDAAK----PGSPAK
Mflv_0842|M.gilvum_PYR-GCK PVRATVFSPEGEADAPDAASLAIDGDPSTVWPIDTYTDPVPFPN-FKNGV
Mvan_6064|M.vanbaalenii_PYR-1 PVSVTVFSPEGEADAPKLAGLAIDGNPATVWPIDTYTDAAPFPN-FKNGV
MSMEG_6929|M.smegmatis_MC2_155 PVRATVFSPEGEADNPGQAELAIDGSSSTMWSTDTYSDPVPFPG-FKNGV
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M PTKATVFSPDGEADNPGQADMAIDGDSTTSWETDTYNDPVPFPG-FKNGV
MUL_5063|M.ulcerans_Agy99 PTKATVFSPDGEADNPGQADMAIDGDSTTSWETDTYNDPVPFPG-FKNGV
Mb3940|M.bovis_AF2122/97 PTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPS-FKNGV
Rv3910|M.tuberculosis_H37Rv PTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPS-FKNGV
MAV_5298|M.avium_104 PTRASVFSLDGDADNPGTAGQAIDGDPSTAWATEVYTDAVPFPS-FKQGE
MLBr_02700|M.leprae_Br4923 PTKATVFSPDGEADNPDDAGLAIDGNPATSWQTDIYNDAVPFPG-FKNGV
MAB_4937|M.abscessus_ATCC_1997 IVQATVFPPGPDADQPGKAGLAVDGNPSTSWITDTYTDADPFPVLFKPGV
Mflv_0842|M.gilvum_PYR-GCK GLMLQLSEPARIGSVTVNLNSTGTAVQIRSSSTATPSSLEDTTALTEPTT
Mvan_6064|M.vanbaalenii_PYR-1 GLMLQLPEPAKIGSVTVNLNSTGTSVQIRSSETATPSSLEDTTALTDPTP
MSMEG_6929|M.smegmatis_MC2_155 GLILQLPQPTVIGSVDLNVTSTGTAVQLRAANSNSPSSLSDTTELTSPTT
TH_2416|M.thermoresistible__bu --------------------------------------------------
MMAR_5474|M.marinum_M GLMLQLPQPTVVGSVTLDVPSTGTKVEIRSSPTPNPSKLDDTTVLTSATA
MUL_5063|M.ulcerans_Agy99 GLVLQLPQPTVVGSVTLDVPSTGTNVEIRSSPTPNPSKLDDTTVLTSATA
Mb3940|M.bovis_AF2122/97 GLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATA
Rv3910|M.tuberculosis_H37Rv GLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATA
MAV_5298|M.avium_104 GLILQLPSPTVVGQVSIDTPSTGTKVEIRAASSPTPAGLNDTTVLAPAFT
MLBr_02700|M.leprae_Br4923 GLMLHLPKPTVVSAVTIDVASIGTKVEIRSASTPTPAKLADTTVLIPATA
MAB_4937|M.abscessus_ATCC_1997 GLLLDLQSSSALSSVTIESHSVGTQVQIRSADSATPGSINDTKEISATAT
Mflv_0842|M.gilvum_PYR-GCK LKPGSNTIEVDDAEPTSYVLVWVSTLGQVGGQSRSDIAEITLNAAS
Mvan_6064|M.vanbaalenii_PYR-1 VKPGSNTIEVEDAEPTSYVLVWISTLGQVDGESRSDIAEVTLNAAS
MSMEG_6929|M.smegmatis_MC2_155 LKTGSNTISVGRAAPTQYLLVWISTLGTVDGKSKTDISDITVKAAS
TH_2416|M.thermoresistible__bu ----------------------------------------------
MMAR_5474|M.marinum_M LKPGSNTIAVNASSPTSNLLVWISTLGTTDGKSRSAISGLTIRAAS
MUL_5063|M.ulcerans_Agy99 LKPGSNTIAVNASSPTSNLLVWISTLGTTDGKSRSAISQLTIRAAS
Mb3940|M.bovis_AF2122/97 LRPGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS
Rv3910|M.tuberculosis_H37Rv LRPGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS
MAV_5298|M.avium_104 LKPGHNVIPVRAGSPTSNLLVWISTLGTTNGKSQAGFSEITVQAAS
MLBr_02700|M.leprae_Br4923 LKPGHNVIEVNSGSPMSNLLVWISTLGSTGGKSLAVISEITIHTPS
MAB_4937|M.abscessus_ATCC_1997 LQSGKTTIPITSSSQVSHVLVWINKLGSTNGDHHAEISEITVSTAS