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RKPAADTLRVSNTVLDVLKRGDVATALSIRLVRTPEIVLLARSAGFDAVFVDLEHSTITDDATSQINMTA LAAGITPLIHVRSAYAETIGAGLDGGALGIIVPHVDSVEDAEAAVKAARYAPRGERGISSALPFFDFRAV QPEAATAAVDAATLVIAMVESQTALDRIDEIAAVDGVDVLLVGANDLTADIGVPGHHGSPEAWAAYRRVI GAAEAAGKFAGIGGVPIEGGVLREVIQAGMRFVSAGPEIRHLGRAVTAWNHEVRSAM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_6019 | - | - | 100% (268) | HpcH/HpaI aldolase |
| M. vanbaalenii PYR-1 | Mvan_2241 | - | 2e-18 | 31.08% (222) | HpcH/HpaI aldolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4105 | - | 1e-19 | 29.65% (226) | HpcH/HpaI aldolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0401 | - | 3e-17 | 30.84% (227) | hypothetical protein MMAR_0401 |
| M. avium 104 | MAV_1907 | - | 1e-19 | 30.59% (219) | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| M. smegmatis MC2 155 | MSMEG_2565 | - | 5e-16 | 30.53% (226) | 4-hydroxy-2-oxovalerate aldolase |
| M. thermoresistible (build 8) | TH_3347 | - | 5e-38 | 37.77% (233) | PUTATIVE putative HpcH/HpaI aldolase |
| M. ulcerans Agy99 | MUL_1051 | - | 8e-17 | 30.40% (227) | hypothetical protein MUL_1051 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4105|M.gilvum_PYR-GCK -----------MTSRLQQALSSGGPVWGGWVVGPTVIGPEEYAAAGYDYV
MSMEG_2565|M.smegmatis_MC2_155 ----------MTASRLQQALADRQTVWGGWVVGPTILGPEEFAAAGYDYV
MMAR_0401|M.marinum_M ---------MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYV
MUL_1051|M.ulcerans_Agy99 ---------MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYV
MAV_1907|M.avium_104 ----------------------------MWLASGSGYVTEICAGSGIDWV
Mvan_6019|M.vanbaalenii_PYR-1 MRKPAADTLRVSNTVLDVLKRGDVATALSIRLVRTPEIVLLARSAGFDAV
TH_3347|M.thermoresistible__bu ---------------------------MALMHSRTPDVPGLAAAAGYDAV
: :* * *
Mflv_4105|M.gilvum_PYR-GCK GIDVQHSYLSDADVALMLRRLEHVP-IATVVRLPDAAPAPIGRVLDAGAD
MSMEG_2565|M.smegmatis_MC2_155 GFDVQHGYLDDADVALLLRRLEHVP-IATAVRLPSPDPAPIGRVLDAGAD
MMAR_0401|M.marinum_M GFDTQHGYLDDADVAGLLRRLEGVP-IATVVRLPNADPAPIGRVLDAGAD
MUL_1051|M.ulcerans_Agy99 GFDTQHGYLDDADVAGLLRRLEGVP-IATVVRLPNADPGPIGRVLDAGAD
MAV_1907|M.avium_104 LLDSEHAPNDLRTILEQLQVLSGYPDVDVLVRPPSADPVFIKRLLDVGAQ
Mvan_6019|M.vanbaalenii_PYR-1 FVDLEHSTITDDATSQINMTALAAG-ITPLIHVRSAYAETIGAGLDGGAL
TH_3347|M.thermoresistible__bu YIDLEHTATPLETVAMLCAAAAGAD-ISALVRVPSHDPSVIARVLDIGAV
.* :* : :: . . * ** **
Mflv_4105|M.gilvum_PYR-GCK GVIIAMVESAADAAAAVAATRYAPGGVRSFGPLRASLG-------LDPSA
MSMEG_2565|M.smegmatis_MC2_155 AVIIAMVETPEQAAAALAATRYAPEGVRSFGPLRASLG-------HDTVA
MMAR_0401|M.marinum_M AVIIAMIESAEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAE
MUL_1051|M.ulcerans_Agy99 AVIIAMIESAEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAE
MAV_1907|M.avium_104 NLIVPMIDDAGEAARAVAATRYPPEGIRGVGSALARASR-WNRISDYLAT
Mvan_6019|M.vanbaalenii_PYR-1 GIIVPHVDSVEDAEAAVKAARYAPRGERGISSALPFFDFRAVQPEAATAA
TH_3347|M.thermoresistible__bu GVIVPHVNSKSEAESVVHSARFPPAGRRSISGPNPVTGFRPRTAPELAAE
:*:. :: :* .: ::*:.* * *. . . .
Mflv_4105|M.gilvum_PYR-GCK LQERASVFAMIETTRGLAAVDEICRVDGLTGIYVGPADLAISMGHGPTDA
MSMEG_2565|M.smegmatis_MC2_155 LQERASVIAMIETATGVAAVQDIAAVAGLTGLYVGPADLAISMGNQPTDA
MMAR_0401|M.marinum_M LQSRAGVYAMVETAAALSTIDDICAVDGLAGIYVGPADLAISLGTGVVGA
MUL_1051|M.ulcerans_Agy99 LQSRAGVYAMVETAAAVSTIDDICAVDGPAGIYVGPADLAISLGTGVVGA
MAV_1907|M.avium_104 ADASVSLTVQVESLAGMEHLGDIAEVDGVDAVFIGPADLAASMGR--LGQ
Mvan_6019|M.vanbaalenii_PYR-1 VDAATLVIAMVESQTALDRIDEIAAVDGVDVLLVGANDLTADIGVP--GH
TH_3347|M.thermoresistible__bu IDRYTVVAAMVETPQAVESVDDIAAVAGLDMILLGPSDLTAEMGIH--GD
: . : . :*: .: : :*. * * : :*. **: .:* .
Mflv_4105|M.gilvum_PYR-GCK WSRRDVFDVILTAQRAAAAAGVVSGIHAS--AGSAGNMLAQNGFQMITLA
MSMEG_2565|M.smegmatis_MC2_155 WTHPDVLAAFVTVRQAADAAGLAGGIHAG--TGRAGKAAADMGFRMITLA
MMAR_0401|M.marinum_M LDHPAVRQAVVGIHRAASAASLHTGIHAG--AAKAGKAMAQLGFEMITLA
MUL_1051|M.ulcerans_Agy99 LDHAAVRQAVVGIHRAASAANLHTGIHAG--AAKAGKAMAQLGFEMITLA
MAV_1907|M.avium_104 PEHPDVVNTIETALAAIVELGKSAGVNAF--NKAIAQRYLAAGASFVLVG
Mvan_6019|M.vanbaalenii_PYR-1 HGSPEAWAAYRRVIGAAEAAGKFAGIGGVPIEGGVLREVIQAGMRFVSAG
TH_3347|M.thermoresistible__bu FENHRFHEAVGAVAEACREHGVAFGIAGIRSPD-LLAHFVDLGLRFISAG
. * . *: . * :: .
Mflv_4105|M.gilvum_PYR-GCK SESQALRRGAAAHLSDARGESG--DGR---
MSMEG_2565|M.smegmatis_MC2_155 SESQALRRGAVEHLDEATGAGGGHEQRGYL
MMAR_0401|M.marinum_M AESQALRRGAAEYLNEATAGTR--------
MUL_1051|M.ulcerans_Agy99 AESQALRRGAAEYLNEATAGTR--------
MAV_1907|M.avium_104 ADVALLARGAEKLVDEYKEMRS--------
Mvan_6019|M.vanbaalenii_PYR-1 PEIRHLGRAVTAWNHEVRSAM---------
TH_3347|M.thermoresistible__bu TDVGMLTDAASARARELRALHRSHRT----
.: * .. :