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M. thermoresistible (build 8) TH_3347 (-)

annotation: putative HpcH/HpaI aldolase
coordinates: 3446210 - 3446947
length: 246

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3347--100% (246)putative HpcH/HpaI aldolase
M. thermoresistible (build 8)TH_0281-1e-0730.26% (152) 4-hydroxy-2-oxovalerate aldolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4105-7e-2234.95% (186) HpcH/HpaI aldolase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0401-3e-2236.61% (183) hypothetical protein MMAR_0401
M. avium 104MAV_1907-4e-2430.43% (230) 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
M. smegmatis MC2 155MSMEG_2565-2e-2037.70% (183) 4-hydroxy-2-oxovalerate aldolase
M. ulcerans Agy99MUL_1051-8e-2236.61% (183) hypothetical protein MUL_1051
M. vanbaalenii PYR-1Mvan_6019-6e-3837.77% (233) HpcH/HpaI aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4105|M.gilvum_PYR-GCK          -----------MTSRLQQALSSGGPVWGGWVVGPTVIGPEEYAAAGYDYV
MSMEG_2565|M.smegmatis_MC2_155      ----------MTASRLQQALADRQTVWGGWVVGPTILGPEEFAAAGYDYV
MMAR_0401|M.marinum_M               ---------MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYV
MUL_1051|M.ulcerans_Agy99           ---------MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYV
MAV_1907|M.avium_104                ----------------------------MWLASGSGYVTEICAGSGIDWV
TH_3347|M.thermoresistible__bu      ---------------------------MALMHSRTPDVPGLAAAAGYDAV
Mvan_6019|M.vanbaalenii_PYR-1       MRKPAADTLRVSNTVLDVLKRGDVATALSIRLVRTPEIVLLARSAGFDAV
                                                                      :         :* * *

Mflv_4105|M.gilvum_PYR-GCK          GIDVQHSYLSDADVALMLRRLEHVP-IATVVRLPDAAPAPIGRVLDAGAD
MSMEG_2565|M.smegmatis_MC2_155      GFDVQHGYLDDADVALLLRRLEHVP-IATAVRLPSPDPAPIGRVLDAGAD
MMAR_0401|M.marinum_M               GFDTQHGYLDDADVAGLLRRLEGVP-IATVVRLPNADPAPIGRVLDAGAD
MUL_1051|M.ulcerans_Agy99           GFDTQHGYLDDADVAGLLRRLEGVP-IATVVRLPNADPGPIGRVLDAGAD
MAV_1907|M.avium_104                LLDSEHAPNDLRTILEQLQVLSGYPDVDVLVRPPSADPVFIKRLLDVGAQ
TH_3347|M.thermoresistible__bu      YIDLEHTATPLETVAMLCAAAAGAD-ISALVRVPSHDPSVIARVLDIGAV
Mvan_6019|M.vanbaalenii_PYR-1       FVDLEHSTITDDATSQINMTALAAG-ITPLIHVRSAYAETIGAGLDGGAL
                                     .* :*                    :   ::  .  .  *   ** ** 

Mflv_4105|M.gilvum_PYR-GCK          GVIIAMVESAADAAAAVAATRYAPGGVRSFGPLRASLG-------LDPSA
MSMEG_2565|M.smegmatis_MC2_155      AVIIAMVETPEQAAAALAATRYAPEGVRSFGPLRASLG-------HDTVA
MMAR_0401|M.marinum_M               AVIIAMIESAEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAE
MUL_1051|M.ulcerans_Agy99           AVIIAMIESAEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAE
MAV_1907|M.avium_104                NLIVPMIDDAGEAARAVAATRYPPEGIRGVGSALARASR-WNRISDYLAT
TH_3347|M.thermoresistible__bu      GVIVPHVNSKSEAESVVHSARFPPAGRRSISGPNPVTGFRPRTAPELAAE
Mvan_6019|M.vanbaalenii_PYR-1       GIIVPHVDSVEDAEAAVKAARYAPRGERGISSALPFFDFRAVQPEAATAA
                                     :*:. ::   :*  .: ::*:.* * *. .   .  .            

Mflv_4105|M.gilvum_PYR-GCK          LQERASVFAMIETTRGLAAVDEICRVDGLTGIYVGPADLAISMGHGPTDA
MSMEG_2565|M.smegmatis_MC2_155      LQERASVIAMIETATGVAAVQDIAAVAGLTGLYVGPADLAISMGNQPTDA
MMAR_0401|M.marinum_M               LQSRAGVYAMVETAAALSTIDDICAVDGLAGIYVGPADLAISLGTGVVGA
MUL_1051|M.ulcerans_Agy99           LQSRAGVYAMVETAAAVSTIDDICAVDGPAGIYVGPADLAISLGTGVVGA
MAV_1907|M.avium_104                ADASVSLTVQVESLAGMEHLGDIAEVDGVDAVFIGPADLAASMGR--LGQ
TH_3347|M.thermoresistible__bu      IDRYTVVAAMVETPQAVESVDDIAAVAGLDMILLGPSDLTAEMGIH--GD
Mvan_6019|M.vanbaalenii_PYR-1       VDAATLVIAMVESQTALDRIDEIAAVDGVDVLLVGANDLTADIGVP--GH
                                     :  . : . :*:  .:  : :*. * *   : :*. **: .:*    . 

Mflv_4105|M.gilvum_PYR-GCK          WSRRDVFDVILTAQRAAAAAGVVSGIHAS--AGSAGNMLAQNGFQMITLA
MSMEG_2565|M.smegmatis_MC2_155      WTHPDVLAAFVTVRQAADAAGLAGGIHAG--TGRAGKAAADMGFRMITLA
MMAR_0401|M.marinum_M               LDHPAVRQAVVGIHRAASAASLHTGIHAG--AAKAGKAMAQLGFEMITLA
MUL_1051|M.ulcerans_Agy99           LDHAAVRQAVVGIHRAASAANLHTGIHAG--AAKAGKAMAQLGFEMITLA
MAV_1907|M.avium_104                PEHPDVVNTIETALAAIVELGKSAGVNAF--NKAIAQRYLAAGASFVLVG
TH_3347|M.thermoresistible__bu      FENHRFHEAVGAVAEACREHGVAFGIAGIRSPD-LLAHFVDLGLRFISAG
Mvan_6019|M.vanbaalenii_PYR-1       HGSPEAWAAYRRVIGAAEAAGKFAGIGGVPIEGGVLREVIQAGMRFVSAG
                                            .      *    .   *: .              *  ::  .

Mflv_4105|M.gilvum_PYR-GCK          SESQALRRGAAAHLSDARGESG--DGR---
MSMEG_2565|M.smegmatis_MC2_155      SESQALRRGAVEHLDEATGAGGGHEQRGYL
MMAR_0401|M.marinum_M               AESQALRRGAAEYLNEATAGTR--------
MUL_1051|M.ulcerans_Agy99           AESQALRRGAAEYLNEATAGTR--------
MAV_1907|M.avium_104                ADVALLARGAEKLVDEYKEMRS--------
TH_3347|M.thermoresistible__bu      TDVGMLTDAASARARELRALHRSHRT----
Mvan_6019|M.vanbaalenii_PYR-1       PEIRHLGRAVTAWNHEVRSAM---------
                                    .:   *  ..     :