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MWLASGSGYVTEICAGSGIDWVLLDSEHAPNDLRTILEQLQVLSGYPDVDVLVRPPSADPVFIKRLLDVG AQNLIVPMIDDAGEAARAVAATRYPPEGIRGVGSALARASRWNRISDYLATADASVSLTVQVESLAGMEH LGDIAEVDGVDAVFIGPADLAASMGRLGQPEHPDVVNTIETALAAIVELGKSAGVNAFNKAIAQRYLAAG ASFVLVGADVALLARGAEKLVDEYKEMRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1907 | - | - | 100% (239) | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| M. avium 104 | MAV_2618 | - | e-108 | 81.28% (235) | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| M. avium 104 | MAV_5121 | - | 1e-24 | 30.77% (234) | HpcH/HpaI aldolase/citrate lyase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4105 | - | 2e-22 | 31.14% (228) | HpcH/HpaI aldolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0401 | - | 4e-28 | 35.71% (238) | hypothetical protein MMAR_0401 |
| M. smegmatis MC2 155 | MSMEG_2565 | - | 2e-24 | 32.63% (236) | 4-hydroxy-2-oxovalerate aldolase |
| M. thermoresistible (build 8) | TH_3347 | - | 4e-24 | 30.43% (230) | PUTATIVE putative HpcH/HpaI aldolase |
| M. ulcerans Agy99 | MUL_1051 | - | 2e-26 | 35.29% (238) | hypothetical protein MUL_1051 |
| M. vanbaalenii PYR-1 | Mvan_2241 | - | 3e-23 | 29.74% (232) | HpcH/HpaI aldolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4105|M.gilvum_PYR-GCK --MTSRLQQALSSGGPVWGGWVVGPTVIGPEEYAAAGYDYVGIDVQHSYL
Mvan_2241|M.vanbaalenii_PYR-1 --MASRLQDALADNAQIWGGWVVGPTVLGPEEFAAAGYDYVGFDVQHGYL
MSMEG_2565|M.smegmatis_MC2_155 -MTASRLQQALADRQTVWGGWVVGPTILGPEEFAAAGYDYVGFDVQHGYL
MMAR_0401|M.marinum_M MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYVGFDTQHGYL
MUL_1051|M.ulcerans_Agy99 MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYVGFDTQHGYL
MAV_1907|M.avium_104 -------------------MWLASGSGYVTEICAGSGIDWVLLDSEHAPN
TH_3347|M.thermoresistible__bu ------------------MALMHSRTPDVPGLAAAAGYDAVYIDLEHTAT
: . : . * :* * * :* :*
Mflv_4105|M.gilvum_PYR-GCK SDADVALMLRRLEHVP-IATVVRLPDAAPAPIGRVLDAGADGVIIAMVES
Mvan_2241|M.vanbaalenii_PYR-1 SDADVALLLRRLEHVP-IATVVRLPGVDAAPIGRVLDAGADGVVIAMVES
MSMEG_2565|M.smegmatis_MC2_155 DDADVALLLRRLEHVP-IATAVRLPSPDPAPIGRVLDAGADAVIIAMVET
MMAR_0401|M.marinum_M DDADVAGLLRRLEGVP-IATVVRLPNADPAPIGRVLDAGADAVIIAMIES
MUL_1051|M.ulcerans_Agy99 DDADVAGLLRRLEGVP-IATVVRLPNADPGPIGRVLDAGADAVIIAMIES
MAV_1907|M.avium_104 DLRTILEQLQVLSGYPDVDVLVRPPSADPVFIKRLLDVGAQNLIVPMIDD
TH_3347|M.thermoresistible__bu PLETVAMLCAAAAGAD-ISALVRVPSHDPSVIARVLDIGAVGVIVPHVNS
: : . ** *. . * *:** ** :::. ::
Mflv_4105|M.gilvum_PYR-GCK AADAAAAVAATRYAPGGVRSFGPLRASLG-------LDPSALQERASVFA
Mvan_2241|M.vanbaalenii_PYR-1 AAQAAAAVAATRYAPGGVRSFGPLRAGLG-------IEPAALQARASVFA
MSMEG_2565|M.smegmatis_MC2_155 PEQAAAALAATRYAPEGVRSFGPLRASLG-------HDTVALQERASVIA
MMAR_0401|M.marinum_M AEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAELQSRAGVYA
MUL_1051|M.ulcerans_Agy99 AEQAAAAVAATRYPPAGVRSYGPLRASLG-------TDPAELQSRAGVYA
MAV_1907|M.avium_104 AGEAARAVAATRYPPEGIRGVGSALARASRWNRIS-DYLATADASVSLTV
TH_3347|M.thermoresistible__bu KSEAESVVHSARFPPAGRRSISGPNPVTGFRPRTAPELAAEIDRYTVVAA
:* .: ::*:.* * *. . . . : . : .
Mflv_4105|M.gilvum_PYR-GCK MIETTRGLAAVDEICRVDGLTGIYVGPADLAISMGHGPTDAWSRRDVFDV
Mvan_2241|M.vanbaalenii_PYR-1 MVETARGLAAIDEICRVEGLTGIYVGPADLAISLGHGPTEAWTRPDVLNA
MSMEG_2565|M.smegmatis_MC2_155 MIETATGVAAVQDIAAVAGLTGLYVGPADLAISMGNQPTDAWTHPDVLAA
MMAR_0401|M.marinum_M MVETAAALSTIDDICAVDGLAGIYVGPADLAISLGTGVVGALDHPAVRQA
MUL_1051|M.ulcerans_Agy99 MVETAAAVSTIDDICAVDGPAGIYVGPADLAISLGTGVVGALDHAAVRQA
MAV_1907|M.avium_104 QVESLAGMEHLGDIAEVDGVDAVFIGPADLAASMGR--LGQPEHPDVVNT
TH_3347|M.thermoresistible__bu MVETPQAVESVDDIAAVAGLDMILLGPSDLTAEMGIH--GDFENHRFHEA
:*: .: : :*. * * : :**:**: .:* . . .
Mflv_4105|M.gilvum_PYR-GCK ILTAQRAAAAAGVVSGIHAS-AGSAGNMLAQNGFQMITLASESQALRRGA
Mvan_2241|M.vanbaalenii_PYR-1 MQHLQRTAAKAGLVTGIHAN-TGTIGNAMAQKGFQMITLASESQALRRGA
MSMEG_2565|M.smegmatis_MC2_155 FVTVRQAADAAGLAGGIHAG-TGRAGKAAADMGFRMITLASESQALRRGA
MMAR_0401|M.marinum_M VVGIHRAASAASLHTGIHAG-AAKAGKAMAQLGFEMITLAAESQALRRGA
MUL_1051|M.ulcerans_Agy99 VVGIHRAASAANLHTGIHAG-AAKAGKAMAQLGFEMITLAAESQALRRGA
MAV_1907|M.avium_104 IETALAAIVELGKSAGVNAF-NKAIAQRYLAAGASFVLVGADVALLARGA
TH_3347|M.thermoresistible__bu VGAVAEACREHGVAFGIAGIRSPDLLAHFVDLGLRFISAGTDVGMLTDAA
. : . *: . * :: .:: * .*
Mflv_4105|M.gilvum_PYR-GCK AAHLSDARGES---GDGR--
Mvan_2241|M.vanbaalenii_PYR-1 AAHLAEATGQSVAPGQQRYC
MSMEG_2565|M.smegmatis_MC2_155 VEHLDEATGAGGGHEQRGYL
MMAR_0401|M.marinum_M AEYLNEATAGTR--------
MUL_1051|M.ulcerans_Agy99 AEYLNEATAGTR--------
MAV_1907|M.avium_104 EKLVDEYKEMRS--------
TH_3347|M.thermoresistible__bu SARARELRALHRSHRT----
: