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MVTRPEGVSDGQIAEGEGQRRREDPFGSGGVGRRDVGCRGRPAMRSVAGASTQVEVPVPRGGRRADAGGA QRRRTRGWQPRATSAAPGERRAQARPGRGDGAVADLAARSSLGRPSPFTDLETLREAAGLPVSKFAPLAG IPERTYRRRLARLRAGSADKGPWPAPVVDRIEALAAKYAEQWPAWGYRKIAALMRADGYEVTNSSVQRAL RRRGLLLPQGFRADRKSWAALRRRVFHDPPTERNRVWQTDFSEFETAHGGIWRISAVIDYVTKYCLAITV TPTSRGRDAVSCVRLAVEEATRVLNLADLRLDRADMDVLDADDNVIGRTPASIAIVSDNGPCYRGRDFQT LFCGHDPLLRHIRTRIKSPQTNGVIERFFETLKYEHLFRGYIGDGDALDMEAHRFRIIYNTIRPHQALQD RTPKQAYLAAKTPENLPTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5965 | - | - | 100% (440) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0458 | - | 8e-11 | 24.85% (334) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_1111 | - | 1e-10 | 28.03% (157) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4763 | - | 7e-11 | 25.59% (211) | integrase catalytic subunit |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3784 | - | 2e-12 | 27.93% (179) | transposase, ISMyma01_aa2-like protein |
| M. avium 104 | MAV_3347 | - | 8e-07 | 37.78% (90) | transposase |
| M. smegmatis MC2 155 | MSMEG_6600 | - | 7e-08 | 36.27% (102) | transposase |
| M. thermoresistible (build 8) | TH_2026 | - | 1e-07 | 35.56% (90) | transposase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3347|M.avium_104 --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155 --------------------------------------------------
TH_2026|M.thermoresistible__bu MPLLRHLDQNTGLPVRRPKPRRYEHPAPGDLVHVDVKKLGRIPDGGGHRK
Mflv_4763|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3784|M.marinum_M --------------------------------------------------
Mvan_5965|M.vanbaalenii_PYR-1 -------------------------------------MMVTRPEGVSDGQ
MAV_3347|M.avium_104 -----------------------------MKCELLKNAQLTPEVFVSHRN
MSMEG_6600|M.smegmatis_MC2_155 ---------------------------------------------MVHRN
TH_2026|M.thermoresistible__bu LGRQAGRRNRCGMGYTFLHHAVDDHSRLAYSEDLADERKETAAGFWKRAS
Mflv_4763|M.gilvum_PYR-GCK --------------------------MPASGDHRVDVAPLDCPVRRHESQ
MMAR_3784|M.marinum_M --------------------------------------------------
Mvan_5965|M.vanbaalenii_PYR-1 IAEGEGQRRR-------------EDPFGSGGVGRRDVGCRGRPAMRSVAG
MAV_3347|M.avium_104 APLSETGRLRLARCVVEDGWSLRR-------------------------A
MSMEG_6600|M.smegmatis_MC2_155 APLSETGRLRLARCVVDDGWSRRR-------------------------A
TH_2026|M.thermoresistible__bu AFFADHG-ITVKRVLTDNGSCYRSKNFAEALGPDIAHKRTRPYRPQTNGK
Mflv_4763|M.gilvum_PYR-GCK RGQTAQGTRSRERPAQEAGRQPGPRHR---------------------HA
MMAR_3784|M.marinum_M --------------------------------------------------
Mvan_5965|M.vanbaalenii_PYR-1 ASTQVEVPVPRGGRRADAGGAQRRRTRG--------------WQPRATSA
MAV_3347|M.avium_104 AERFQVAVTTAQRWASRYRELGPAG-------MADRSSRPLR--------
MSMEG_6600|M.smegmatis_MC2_155 AERFQVSVTTVCRWVNRYLELGEAG-------MADRSSRPHH--------
TH_2026|M.thermoresistible__bu VERFNRTLTTEWAYAQTYRSEAERAGTYQHWLHHYNHHRPHTGIGGMTPI
Mflv_4763|M.gilvum_PYR-GCK QGDFGGKLLTPNRKRSAVIALRERFG------VSERRACTVVG-------
MMAR_3784|M.marinum_M -------------------MLRERFG------VSERRACTVVG-------
Mvan_5965|M.vanbaalenii_PYR-1 APGERRAQARPGRGDGAVADLAARSSLGRPSPFTDLETLREAAG------
MAV_3347|M.avium_104 ----------SPNQTPTRTER----------------------RIIKVRV
MSMEG_6600|M.smegmatis_MC2_155 ----------SPNRTPTRTER----------------------RIIGVRV
TH_2026|M.thermoresistible__bu DRLRVHNLPVKNNQCPTSISRPPHCRGSKEAVSQFDALCANEPELAALRA
Mflv_4763|M.gilvum_PYR-GCK -----------LHRSTMRLTP---------------------APVTTEEA
MMAR_3784|M.marinum_M -----------LHRSTMRLQS---------------------APITTEEA
Mvan_5965|M.vanbaalenii_PYR-1 ---LPVSKFAPLAGIPERTYR---------------------RRLARLRA
. : ..
MAV_3347|M.avium_104 LRR-----------WGPAR--------IAYLLGLNVS--TVHRVLTRYKL
MSMEG_6600|M.smegmatis_MC2_155 TRR-----------WGPAR--------IAYLLRLNVS--TVHNVLRRYRI
TH_2026|M.thermoresistible__bu SVRDFLKADRAEFGWQPDVDSWLGQWDEAFSARLGAAGFVGLTIPKKYGG
Mflv_4763|M.gilvum_PYR-GCK ELR-------------------------AWLRRFSTD-------RPRWGW
MMAR_3784|M.marinum_M ELR-------------------------AWLRRFSTD-------WPRWGW
Mvan_5965|M.vanbaalenii_PYR-1 GSAD------------------KGPWPAPVVDRIEALAAKYAEQWPAWGY
. : . :
MAV_3347|M.avium_104 AKLRWLDR--------------ATGQVVRRMEAACCGDLVHVDVKK---L
MSMEG_6600|M.smegmatis_MC2_155 ARLRWLDR--------------ATGRVVRRMESAACGDLVHADVKK---L
TH_2026|M.thermoresistible__bu AGLTHLHRYVVIEELLAQGAPVAAHWVADRQVVPSLLSYGSEDQRKRL-L
Mflv_4763|M.gilvum_PYR-GCK RRAAKMAR--------------RAGWKANNKRIRRLWREEGLRVPQR--R
MMAR_3784|M.marinum_M RRAAKMAR--------------RAGWAVNNKRIRRLWREEGLRVPQR--R
Mvan_5965|M.vanbaalenii_PYR-1 RKIAALMR--------------ADGYEVTNSSVQRALRRRGLLLPQGFRA
: * . . :
MAV_3347|M.avium_104 GKIPAGGGWRMLGRTVG--NRNAQADKTSGERSKHRHPLRGYHFLHT-AI
MSMEG_6600|M.smegmatis_MC2_155 GKIPAGGGWRMLGRTAG--RKNSLADKSSGVKTRNGDPARGYHFLHS-AL
TH_2026|M.thermoresistible__bu PRIAAGTFFSSIGMSEHGAGSDLAAVQTKAVSADGGWLLNGTKVWTSGAH
Mflv_4763|M.gilvum_PYR-GCK RKKRLTGIGVAVGAMSPIRPNVIWAMDFQFDTTADGRTLKMLNVIDEFTR
MMAR_3784|M.marinum_M KKKRLTGIGVEVGAMSPICPNVIWAMDFQFDTTADGRTLKMLNVIDEFTR
Mvan_5965|M.vanbaalenii_PYR-1 DRKSWAALRRRVFHDPPTERNRVWQTDFSEFETAHGGIWRISAVIDYVTK
: : . . : . . :
MAV_3347|M.avium_104 DAHSRLAYSELL---------------------TDERKETAAAFWLRAQA
MSMEG_6600|M.smegmatis_MC2_155 DAHSRLVYSEML---------------------ADERKDTASEFWKRANS
TH_2026|M.thermoresistible__bu KAHQVVVLARTS---------------------PPDRQMRHSGFSQFLVP
Mflv_4763|M.gilvum_PYR-GCK EALAIEVDRAIN---------------------ADG--------VVDVLD
MMAR_3784|M.marinum_M EALAIEVDRAIN---------------------ADG--------VVAVLD
Mvan_5965|M.vanbaalenii_PYR-1 YCLAITVTPTSRGRDAVSCVRLAVEEATRVLNLADLRLDRADMDVLDADD
. . .
MAV_3347|M.avium_104 WFTTCGFTVRKVLTDNGSCYRSHAFRDALG------------------DI
MSMEG_6600|M.smegmatis_MC2_155 WFFEQGVIVRTVLTDNGSCYRSHSFREALGD-----------------DI
TH_2026|M.thermoresistible__bu CGTDGVRIEPILMMNGDHHFNEVSFEDVFVPESDVLGQIGQGWHQVTAEL
Mflv_4763|M.gilvum_PYR-GCK RLALTYGAPHYVRFDNGPEFVANAVADWCRFNSAGSLFIDP---------
MMAR_3784|M.marinum_M RLTAQRATPHYVRFDNGPEFVAHAVSDWCRFNSAGSLFIDP---------
Mvan_5965|M.vanbaalenii_PYR-1 NVIGRTPASIAIVSDNGPCYRGRDFQTLFCGHDPLLRHIRTR--------
: :.. : .
MAV_3347|M.avium_104 EHRRTRP------------------YRPQTNGKVERFH------------
MSMEG_6600|M.smegmatis_MC2_155 EHRRTRP------------------YRPQTNGKVERFH------------
TH_2026|M.thermoresistible__bu SFERSGPERILSTVPLIVAAIRVLGNTPTTDDTTAGILGDLLARLISLRQ
Mflv_4763|M.gilvum_PYR-GCK -------------------------GSPWQNAWIESFN------------
MMAR_3784|M.marinum_M -------------------------GSPWQNAWIESFN------------
Mvan_5965|M.vanbaalenii_PYR-1 ------------------------IKSPQTNGVIERFF------------
* : :
MAV_3347|M.avium_104 ------RTLADEWAYARLYRSDAERCAEFPR-----WLHTYNHHRGHTAL
MSMEG_6600|M.smegmatis_MC2_155 ------RTLADEWAYARLYTSDEQRCQEYPR-----WLHTYNHHRGHTAL
TH_2026|M.thermoresistible__bu LSIWVARTLNESHAAANQAALVKDLGTQFEQESTDVIIDVLNAVEATPEL
Mflv_4763|M.gilvum_PYR-GCK ------GRLRDELLNLWRFDSLLEARVIIED-----WRRDYNANRPHSAH
MMAR_3784|M.marinum_M ------GRLRDELLNSWRFDSLLEAQVLIED-----WRRDYNANRPHTAH
Mvan_5965|M.vanbaalenii_PYR-1 ------ETLKYEHLFRGYIGDGDALDMEAHR-----FRIIYNTIRPHQAL
* . * .
MAV_3347|M.avium_104 GGQPPATRVPN------------LSGQYI------
MSMEG_6600|M.smegmatis_MC2_155 GGQPPASRVPN------------LSGQYT------
TH_2026|M.thermoresistible__bu AALSATAMLHKPVFTLRGGTNEVLRGVVARGMGLR
Mflv_4763|M.gilvum_PYR-GCK GELTPAEFALQ------------WTTTHQPQVA--
MMAR_3784|M.marinum_M GELTPTEFALQ------------WTTTHQPQAA--
Mvan_5965|M.vanbaalenii_PYR-1 QDRTPKQAYLA-----------AKTPENLPTS---
..