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VSVARFIADQRTKYRVPHTITCVLLSVSESWFYKWITRAENTNGLHTDTDRRRAELDTAVAAAFKAAKGL HGSPRLIADLRDVGWEVSEKTVADSMRRQGLVARHIKRRNGLTRQGKTAPKFPDLVKRNFTADAPNRKWV GDMTEIPTGSGQKLYLATVIDLYSRRLLGAAMGLHPDADLACAAIKMAVTARGGRQGIWRDEESERVIFH TDRGSTYTANAFTKLCRQLGIRQSMGRVGSCFDNAAAEAFFSSLEWEVLSRNQFRDTIHAQAVVIDWCYT FYNHQRRHSAADGLSPVNYEIRESKSKPEAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2522 | - | - | 100% (311) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0583 | - | 3e-46 | 38.56% (319) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0575 | - | 3e-46 | 38.56% (319) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 9e-26 | 31.43% (280) | transposase |
| M. gilvum PYR-GCK | Mflv_0576 | - | 4e-43 | 37.93% (319) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3475 | - | 2e-26 | 30.48% (315) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 2e-31 | 35.02% (237) | transposase |
| M. marinum M | MMAR_3786 | - | 3e-31 | 32.31% (260) | transposase |
| M. avium 104 | MAV_1454 | - | 2e-25 | 30.43% (253) | transposase |
| M. smegmatis MC2 155 | MSMEG_4105 | - | 1e-33 | 31.99% (297) | transposase subunit |
| M. thermoresistible (build 8) | TH_3162 | - | 4e-36 | 38.66% (238) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2522|M.vanbaalenii_PYR-1 --------------------------------------------MSVARF
TH_3162|M.thermoresistible__bu --------------------------------------------------
Mflv_0576|M.gilvum_PYR-GCK --------------------------------------------MSRFQF
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4105|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3786|M.marinum_M ---------------------------------------MPRQYSSSVRR
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_1454|M.avium_104 --------------------------------------------------
Mvan_2522|M.vanbaalenii_PYR-1 IADQRTKYRVPHTITCVLLSVSESWFYKWITRAENTNGLHTDTDRRR---
TH_3162|M.thermoresistible__bu --------------------------------------------------
Mflv_0576|M.gilvum_PYR-GCK VADRLHAFEVK--WLCAVVEVARSSFYAWLAGADG----RAARRAAD---
MAB_2088|M.abscessus_ATCC_1997 -------------MTRRVLKLARQPYYRWRANPITDAELVEAYR------
MSMEG_4105|M.smegmatis_MC2_155 -MKELAADGIPVAVTCRVLKLARQPYYRWLAAPVTDADLVEAYR------
MMAR_3786|M.marinum_M QIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGVIEGTPSVEADE
Mb2838c|M.bovis_AF2122/97 ------------------MPIAPSTYYDHINREPSRRELRDGELK-----
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELK-----
MAV_1454|M.avium_104 --------------------MALSTYYDTKARVPSARALRDAVLG-----
Mvan_2522|M.vanbaalenii_PYR-1 ----------------AELDTAVAAAFKAAKGLHGSPRLIADLRD-----
TH_3162|M.thermoresistible__bu ------------------LDAKVAAFHKASDGVYGAPRILADLRE-----
Mflv_0576|M.gilvum_PYR-GCK ----------------EALAERIRAVHDEDN-TYGAPRITAELNDGAP--
MAB_2088|M.abscessus_ATCC_1997 --------------------ANALFDAHGEDPEFGYRYLVEEAREAG---
MSMEG_4105|M.smegmatis_MC2_155 --------------------ANALFDAHHEDPEFGYRYLAEEARDAG---
MMAR_3786|M.marinum_M LAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAITEGLIARGHSA
Mb2838c|M.bovis_AF2122/97 --------------------EHISRVHAANYGVYGARKVWLTLNREG---
Rv3475|M.tuberculosis_H37Rv --------------------EHISRVHAANYGVYGARKVWLTLNREG---
MAV_1454|M.avium_104 --------------------PALCQLWKDNYCVYGARKLWKTARREG---
:
Mvan_2522|M.vanbaalenii_PYR-1 -----------------VGWEVSEKTVADSMRRQGLVARHIKRRNGLTRQ
TH_3162|M.thermoresistible__bu -----------------DGEKVSRKTVAASLRRQGLAGISPRTFAPVTTI
Mflv_0576|M.gilvum_PYR-GCK -----------------EGQRVNHKRVARVMRGAGIAGYRRRRRVKTTVA
MAB_2088|M.abscessus_ATCC_1997 -------------------EPMAERTAWRICSQQQLWSVFGK-KRGKNGK
MSMEG_4105|M.smegmatis_MC2_155 -------------------EPMAERTAWRICSHNRLWSVFGKRKRGKNGK
MMAR_3786|M.marinum_M RSACRVTGLARSLLQYHRRRLVPDREVRRLIVADTITEIYQR-SRGTYGR
Mb2838c|M.bovis_AF2122/97 -------------------IEVARCTVERLMTKLGLSGTTRGKARRTTIA
Rv3475|M.tuberculosis_H37Rv -------------------IEVARCTVERLMTKLGLSGTTRGKARRTTIA
MAV_1454|M.avium_104 -------------------HDVGRDQVARLMRAAGIEGVRRGKRVRTTKP
: . :
Mvan_2522|M.vanbaalenii_PYR-1 GK----------------------------------------TAPKFP-D
TH_3162|M.thermoresistible__bu VD----------------------------------------LDTPVPKD
Mflv_0576|M.gilvum_PYR-GCK DP----------------------------------------ANQKVP-D
MAB_2088|M.abscessus_ATCC_1997 P------------------------------------------GPPVHDD
MSMEG_4105|M.smegmatis_MC2_155 P------------------------------------------GPPVHDD
MMAR_3786|M.marinum_M KRVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKPNLIGVHTPVD
Mb2838c|M.bovis_AF2122/97 DP-----------------------------------------ATARPAD
Rv3475|M.tuberculosis_H37Rv DP-----------------------------------------ATARPAD
MAV_1454|M.avium_104 DP-----------------------------------------AAARHPD
*
Mvan_2522|M.vanbaalenii_PYR-1 LVKRNFTADAPNRKWVGDMTEIPTGSGQKLYLATVIDLYSRRLLGAAMGL
TH_3162|M.thermoresistible__bu LVNRRFDVGELDRVWTSDITYLRTGEG-WLYLCAVRDGCSRRVIGWAIDD
Mflv_0576|M.gilvum_PYR-GCK LLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCSRRVAGWAIAD
MAB_2088|M.abscessus_ATCC_1997 LVQRDFTAETPNMLWLSDITEHYTGDG-KLYLCAIKDAFSNRIVGYSIDS
MSMEG_4105|M.smegmatis_MC2_155 LVERDFTAEAPNQLWLADITEHRTGEG-KLYLCAIKDVFSNRIVGYSIDS
MMAR_3786|M.marinum_M LINRRFTATKPNELWCTDITEHPARDG-KVYCCAILDCFSRMIVARTFST
Mb2838c|M.bovis_AF2122/97 LVQRRFGPPAPNRLWVADLTYVSTWAG-FAYVAFVTDAYARRILGWRVAS
Rv3475|M.tuberculosis_H37Rv LVQRRFGPPAPNRLWVADLTYVSTWAG-FAYVAFVTDAYARRILGWRVAS
MAV_1454|M.avium_104 LVKRNFTATAPNQLWVTDLTFVPTWAG-VAYVCFIIDAYSRMIVGWRVAS
*::* * : : *:* * * . : * :. : . .
Mvan_2522|M.vanbaalenii_PYR-1 HPDADLACAAIKMAVTARGGRQGIWRDEESERVIFHTDRGSTYTANAFTK
TH_3162|M.thermoresistible__bu HMHTDLVESAVAMAVAMRG--------QLAEQVVLHADRGCQFTSAQLAR
Mflv_0576|M.gilvum_PYR-GCK HMRTELVIDALKAAAALRG---------SLAGAIFHADHGSQYTSRDFAN
MAB_2088|M.abscessus_ATCC_1997 RMKSRLATAALRNAVGRRG---------VVAGCVVHTDRGSQFRSRKFVQ
MSMEG_4105|M.smegmatis_MC2_155 RMKSRLATRALHSAVARRG---------DVAGCILHSDRGSQFRSRRFVH
MMAR_3786|M.marinum_M TADTALVNNAVNMAVDHRN---------RSGPTILHADHGTQFTSWSFGE
Mb2838c|M.bovis_AF2122/97 TMATSMVLDAIEQAIWTRQQEGV----LDLKDVIHHTDRGSQYTSIRFSE
Rv3475|M.tuberculosis_H37Rv TMATSMVLDAIEQAIWTRQQEGV----LDLKDVIHHTDRGSQYTSIRFSE
MAV_1454|M.avium_104 HMRTSMVLDALEMARWSRGN--------MLPGLRCHSDAGSQFTSIRYGE
: :. *: * * *:* * : : .
Mvan_2522|M.vanbaalenii_PYR-1 LCRQLGIRQSMGRVGSCFDNAAAEAFFSSLEWEVLS----RNQFRDTIHA
TH_3162|M.thermoresistible__bu FSRGHNLARSVGRTGVCWDNAQHESFWGTMKVEFYD----RHLWPTKAAA
Mflv_0576|M.gilvum_PYR-GCK LCRDLGVVQSMGAVGSSADNALAESFNAALKREILQD---RACWPDAAIC
MAB_2088|M.abscessus_ATCC_1997 ALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRRWATREEL
MSMEG_4105|M.smegmatis_MC2_155 ALHHHDMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRRWRTREEL
MMAR_3786|M.marinum_M NMRRWGLLGSFGTVGDCFDNAAMESFWARLQVELLN----TRKWATTIEL
Mb2838c|M.bovis_AF2122/97 RLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDV
Rv3475|M.tuberculosis_H37Rv RLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDV
MAV_1454|M.avium_104 RLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIYGPARTGPWKTVEDV
. *.* .* . *** *:. . : :. :
Mvan_2522|M.vanbaalenii_PYR-1 QAVVIDWCYTFYNHQRRHSAADGLSPVNYEI-RESKSKPEAA-----
TH_3162|M.thermoresistible__bu KLAVGDWIERVYNRRRRPSATP-----------AAAATQRSA-----
Mflv_0576|M.gilvum_PYR-GCK RREVFRWLAR-YNTTRRHSYCRHSSPATYERNLTPATLPEAA-----
MAB_2088|M.abscessus_ATCC_1997 RIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA------
MSMEG_4105|M.smegmatis_MC2_155 RIAIVIWIERTYHRRRRQAGLDRLTPIEFEAIMTTPASQAA------
MMAR_3786|M.marinum_M AAAMADYIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA----
Mb2838c|M.bovis_AF2122/97 ELATARWVDW-FNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
Rv3475|M.tuberculosis_H37Rv ELATARWVDW-FNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
MAV_1454|M.avium_104 ELATLSWVYW-HNTSRLHSYLGDIPPAEFEAAFYDAYRTDQPLIGIQ
: .: *