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SKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYALDGQDWEPGQSQLTDVAQVAMVQ NLLTEDNLPSYHREIAMNFSMDGPWGQWVNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGF SPGQNQQGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDENLHMIFYRDVSAAG LDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVIIAVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGE AAWMRDDLGVLIKELEQAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3646 | desA1_1 | - | 100% (338) | acyl- |
| M. ulcerans Agy99 | MUL_0445 | desA1 | e-155 | 77.15% (337) | acyl- |
| M. ulcerans Agy99 | MUL_0187 | desA2 | 3e-37 | 30.92% (262) | acyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 1e-154 | 75.67% (337) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 1e-145 | 73.56% (329) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 1e-154 | 75.67% (337) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 1e-153 | 75.00% (336) | acyl- |
| M. abscessus ATCC 19977 | MAB_3354 | - | 1e-139 | 70.28% (323) | acyl- |
| M. marinum M | MMAR_3704 | desA1_1 | 0.0 | 100.00% (338) | acyl- |
| M. avium 104 | MAV_1793 | - | 1e-176 | 87.83% (337) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5773 | - | 1e-154 | 80.13% (317) | fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-154 | 79.56% (318) | fatty acid desaturase |
| M. vanbaalenii PYR-1 | Mvan_5085 | - | 1e-147 | 74.16% (329) | fatty acid desaturase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3646|M.ulcerans_Agy99 -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MMAR_3704|M.marinum_M -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MAV_1793|M.avium_104 -MPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
Mb0847c|M.bovis_AF2122/97 -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923 -MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
TH_1577|M.thermoresistible__bu -MHENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
Mflv_1668|M.gilvum_PYR-GCK -MSKDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1 -MSKDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
MAB_3354|M.abscessus_ATCC_1997 MAQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKAL
. *:*.** **:**** .** * ******:*******: :
MUL_3646|M.ulcerans_Agy99 DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MMAR_3704|M.marinum_M DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MAV_1793|M.avium_104 GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1 GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
MAB_3354|M.abscessus_ATCC_1997 GGQDWDPEQCKLSEVARVAMVTNLLTEDNLPAYHREIAMNFTMDGPWGTW
.**** * : :*.:**:.*:: **:******:*******.: ***.** *
MUL_3646|M.ulcerans_Agy99 VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MMAR_3704|M.marinum_M VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MAV_1793|M.avium_104 VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1 VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
MAB_3354|M.abscessus_ATCC_1997 VNRWTAEENRHSIAIRDYLVVTRSVDPVELEKLRMEQMTRGFSPGQNRQG
******** **. ::******** ****** **:* :.********
MUL_3646|M.ulcerans_Agy99 QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MMAR_3704|M.marinum_M QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MAV_1793|M.avium_104 QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
Mb0847c|M.bovis_AF2122/97 QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MLBr_02185|M.leprae_Br4923 QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MSMEG_5773|M.smegmatis_MC2_155 QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
TH_1577|M.thermoresistible__bu QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1 EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
MAB_3354|M.abscessus_ATCC_1997 GDELFAESLFDSVAYVSFQELATRVSHRNTGVACAEPIAQELLKHISNDE
**::: **: **:*******:****** .. :.:*::*: ::* **
MUL_3646|M.ulcerans_Agy99 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MMAR_3704|M.marinum_M NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MAV_1793|M.avium_104 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1 NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
MAB_3354|M.abscessus_ATCC_1997 NLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTIPGFRRNAVTI
********:: *.:::.*: *: ::* :* :* ***: :* ***.** *
MUL_3646|M.ulcerans_Agy99 AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MMAR_3704|M.marinum_M AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MAV_1793|M.avium_104 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1 ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
MAB_3354|M.abscessus_ATCC_1997 ATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLK
* **:** ::** ::* ***:****:**:*:.**. *::: : :*:
MUL_3646|M.ulcerans_Agy99 QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MMAR_3704|M.marinum_M QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MAV_1793|M.avium_104 DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKR-EMKNLLVSSSSS----
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKK-AAKNLLVGSSAS----
Mvan_5085|M.vanbaalenii_PYR-1 EAVDKFEVAKQRREERLRQMAEKK-AAKNLLVGSSAS----
MAB_3354|M.abscessus_ATCC_1997 KTASDFDEVKAKYLERQAKRAERQAAKV-------------
: ..*: * : :* : ::