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M. vanbaalenii PYR-1 Mvan_5922 (-)

annotation: peptidase S9 prolyl oligopeptidase
coordinates: 6312264 - 6314144
length: 626

MALPGLISVEDFFNPPTRAAATISPDGTRMAFLAPWKDRLNVWVQGLEPDADEPRCVTADDHRSVMHFEW
TDDPRWLIYLQDTNGDENWHIHRVDLDDPDAAAVDLTPFPGAMAAPLREVRNGTTTVMLNNRDATLLDVH
RLDIATGHLTLIATNPGHVNGWLCSDNGDVFATSLTPDGDVELSRWDSATDTLQPIARFDGSDYPVGIHP
LVITPDGTGVWLGSHRDTDRSRLVRVDLVTGEETEADSHPELDIDPRAIVSPIIPAPLIQDRRTGELLGV
RYFGERQVIRALDPGFGDILTNLENLSDGDVGRLSSDESGLRWVVGFNHDRDPGATYLYDHSTGESRLLF
RPMPHLDPEQLAPMRPVTITSRDGLALHSYLTLPVGVQPEGLPLVLVVHGGPWYRDSWGFDAGVQMLANR
GYAVLQVNFRGSLGYGKAFLKAAVGEFAGKMHDDLIDGVHWAVEQGYADPDRIAILGGSYGGYAALVGVT
FTPDVFTAAVDYVGISDLANFMRTLPPIARPHLANNWHAYVGDPDDPEQLADMMARSPITKVDRIRTPLL
VIQGANDVRVVQAESDNLVAALRARGVEVDYLIQADEGHGAVNPENVIEMWDAVARFLARHLGGRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5922--100% (626)peptidase S9 prolyl oligopeptidase
M. vanbaalenii PYR-1Mvan_4095-4e-3031.29% (310) peptidase S9 prolyl oligopeptidase
M. vanbaalenii PYR-1Mvan_3954-6e-2124.75% (707) peptidase S9 prolyl oligopeptidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0466c-5e-1126.25% (259) peptidase
M. gilvum PYR-GCKMflv_4393-0.083.23% (626) peptidase S9 prolyl oligopeptidase
M. tuberculosis H37RvRv0457c-5e-1126.25% (259) peptidase
M. leprae Br4923MLBr_02226ptrB5e-0523.56% (191) protease II
M. abscessus ATCC 19977MAB_4725-0.067.78% (627) peptidase
M. marinum MMMAR_0779-8e-1930.27% (261) peptidase
M. avium 104MAV_0727-4e-0925.27% (281) protease 2
M. smegmatis MC2 155MSMEG_5523-0.066.61% (623) peptidase
M. thermoresistible (build 8)TH_4519-3e-3435.86% (251) PUTATIVE peptidase S9, prolyl oligopeptidase active site domain
M. ulcerans Agy99MUL_0498ptrB7e-1125.38% (327) protease II (oligopeptidase B), PtrB

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_5922|M.vanbaalenii_PYR-1       ------------------MALPGLISVEDFFNPPTRAAATISPDGTRMAF
Mflv_4393|M.gilvum_PYR-GCK          ------------------MALPDLIPVEDLFNPPTRAAAKISPDGTRMAF
MAB_4725|M.abscessus_ATCC_1997      ------------------MGLPKLITVEEFFEPPVRTSASISPDGTMIAY
MSMEG_5523|M.smegmatis_MC2_155      ------------------MPLPQPISVEDFFRPPVRAAAKISPDGTRIAY
Mb0466c|M.bovis_AF2122/97           -----------MASMTFEP---APDGAD----PYLWLEDVTGAE--ALDW
Rv0457c|M.tuberculosis_H37Rv        --------------MTFEP---APDGAD----PYLWLEDVTGAE--ALDW
MMAR_0779|M.marinum_M               -----------MAPKAPEAPQ-APDAADTTTDPYLWLEDVTGEE--ALDW
MAV_0727|M.avium_104                MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPD--VIAH
MUL_0498|M.ulcerans_Agy99           MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVE--VIAH
MLBr_02226|M.leprae_Br4923          MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPE--VVAY
TH_4519|M.thermoresistible__bu      ------------------VAEQVRATYGASLSPDATAFAHLVDDG---GF
                                                                    *          :      

Mvan_5922|M.vanbaalenii_PYR-1       LAPWKDRLNVWVQG---LEPDADEPRCVTADDHRSVMHFEWTDDPRWLIY
Mflv_4393|M.gilvum_PYR-GCK          LAPSNNRLNVWVEN---LDPESGGLRRVTDDDNRSVLHFEWTDDPRWLIY
MAB_4725|M.abscessus_ATCC_1997      LAPRKNRLNVWVQG---IG--STEARCVTHDETRSVTGFFWVDDPRWLLY
MSMEG_5523|M.smegmatis_MC2_155      LAPWQNRLNIWVEN---VD--GSETRCVTADENRSIYIYEWTGDSRWLLY
Mb0466c|M.bovis_AF2122/97           VRARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYN
Rv0457c|M.tuberculosis_H37Rv        VRARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYN
MMAR_0779|M.marinum_M               VRARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYD
MAV_0727|M.avium_104                LEAESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYY
MUL_0498|M.ulcerans_Agy99           LEAENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYY
MLBr_02226|M.leprae_Br4923          LDAENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYY
TH_4519|M.thermoresistible__bu      PRAVQRFLRGWRAS---------SSRDVELPVVGPVRRVLHSPDGGWLAC
                                      . .                                         :   

Mvan_5922|M.vanbaalenii_PYR-1       LQDTNGDENWHIHRVDLDDP---------------------DAAAVDLTP
Mflv_4393|M.gilvum_PYR-GCK          LQDTNGDENWHVHRVDLDDP---------------------EAPAVDLTP
MAB_4725|M.abscessus_ATCC_1997      VQDSGGDENWHLYRVDLSTP---------------------DATAVDLTP
MSMEG_5523|M.smegmatis_MC2_155      MQDTGGDEYFHVYRADPDDP---------------------AATAVDLTP
Mb0466c|M.bovis_AF2122/97           FWRDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRAD
Rv0457c|M.tuberculosis_H37Rv        FWRDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRAD
MMAR_0779|M.marinum_M               FWRDANNPRGLWRRTTLES----------YRTDAPEWDVLIDVDELGRTD
MAV_0727|M.avium_104                ARTYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVE--AE
MUL_0498|M.ulcerans_Agy99           ARTFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEE--AE
MLBr_02226|M.leprae_Br4923          SRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAE--AE
TH_4519|M.thermoresistible__bu      EVAPDGSDRSQIWVVTTDPD---------------------DRGAHRIDS
                                                                                      

Mvan_5922|M.vanbaalenii_PYR-1       FPGAMAAPLREVRN--GTTTVMLNNRDATLLDVHRLDIATGHLTLIATNP
Mflv_4393|M.gilvum_PYR-GCK          FPGAMALPVREVKN--GRTTVMVNNRDATLLDIHELDIATGDLTLIAKNP
MAB_4725|M.abscessus_ATCC_1997      FPGARLLGLERPYGRSGKVYIQLNHRRIDQIDLYELDIASGELTMLAENP
MSMEG_5523|M.smegmatis_MC2_155      FPGVRTS-FELLKGRPGKVMVQLNKRTSTLMDAAELDIATGELTELAQNP
Mb0466c|M.bovis_AF2122/97           DQKWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQL
Rv0457c|M.tuberculosis_H37Rv        DQKWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQL
MMAR_0779|M.marinum_M               NKKWVWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFEL
MAV_0727|M.avium_104                GHEFFALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EI
MUL_0498|M.ulcerans_Agy99           GHDFFALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EI
MLBr_02226|M.leprae_Br4923          GHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EI
TH_4519|M.thermoresistible__bu      WPPDAPEGAAELIAWDGNRIAAILTGQDGVGSSCLIDPADGSTVVLDRRS
                                                          :             *           . 

Mvan_5922|M.vanbaalenii_PYR-1       GHVNGWLCSDNGDVFATSLTPD--------GDVELSRWDSATDTLQPIAR
Mflv_4393|M.gilvum_PYR-GCK          GHVNGWLSSDDGDLFATALTAD--------GDLELSRWDRDDEALRPIIR
MAB_4725|M.abscessus_ATCC_1997      GGVMAWFCGPNHEVFAQSLTPG--------GDIEFSRYESGA--LRPLCV
MSMEG_5523|M.smegmatis_MC2_155      GTVTNWQAGPNGDLFTSTQTAE--------GDIEIARWDSAAKTLRTIAT
Mb0466c|M.bovis_AF2122/97           PPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETI
Rv0457c|M.tuberculosis_H37Rv        PPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETI
MMAR_0779|M.marinum_M               PEAKSQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMI
MAV_0727|M.avium_104                ADIAAGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAGSGEA-PELV
MUL_0498|M.ulcerans_Agy99           ADIGAGATWAADHRTVYYITVD-----AAWRPDTVWRYRLGSPGS-SERV
MLBr_02226|M.leprae_Br4923          VGIGAGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLGSGQP-SEQV
TH_4519|M.thermoresistible__bu      GGRLVDAWAGAALIRVGPRGYRELIMLHGNTEMALLPSDPGSTTDFGVIL
                                                                      .               

Mvan_5922|M.vanbaalenii_PYR-1       FDGSDYPVGIHP---------LVITPDGTGVWLGSHRDTDRSRLVRVDLV
Mflv_4393|M.gilvum_PYR-GCK          FDGTDYPIGIHP---------LVLTPDGTGVWLGFNRGTDRTRLVHVDLA
MAB_4725|M.abscessus_ATCC_1997      YDGADYPVGMNP---------TQMTPDGSGMWLGSSRDTDRTRLVRLDLA
MSMEG_5523|M.smegmatis_MC2_155      YDGADYPLGIHP---------ISVSPDGTGLWFGSNKGTDRTRLVRLDVA
Mb0466c|M.bovis_AF2122/97           FEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAP
Rv0457c|M.tuberculosis_H37Rv        FEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAP
MMAR_0779|M.marinum_M               FQGAHTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGTELIPLDVP
MAV_0727|M.avium_104                YHEADEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLP
MUL_0498|M.ulcerans_Agy99           YHEPDERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLP
MLBr_02226|M.leprae_Br4923          YHEADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLP
TH_4519|M.thermoresistible__bu      DDHSARRLRRGPDGE------LTKLYQPAKRYPRESTEGYVRALIRSDNG
                                     . .   .                                    .     

Mvan_5922|M.vanbaalenii_PYR-1       TGEE----------------------------TEADSHPELDIDPRAIVS
Mflv_4393|M.gilvum_PYR-GCK          TGEE----------------------------TDVDSHPTFDVDPRAAVS
MAB_4725|M.abscessus_ATCC_1997      TGAE----------------------------STIDSHPAYDLAA----A
MSMEG_5523|M.smegmatis_MC2_155      TGEE----------------------------TEVDSHPSFDLAT----Q
Mb0466c|M.bovis_AF2122/97           TDAS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAG
Rv0457c|M.tuberculosis_H37Rv        TDAS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAG
MMAR_0779|M.marinum_M               TDASSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSG
MAV_0727|M.avium_104                RRDG-VEYSVEHA---VVGGQD------RFLILHNDGAVNFTLTEAPVSD
MUL_0498|M.ulcerans_Agy99           RREG-VEYSVEHA---VIGGQD------RFLILHNDGAVNFTLVEAPVDD
MLBr_02226|M.leprae_Br4923          RRDG-IEYSVEHAPSGLVGGQD------RFLILHNDGAVNFTLVESPVSN
TH_4519|M.thermoresistible__bu      AGYA----------------------RLLEVTTTADGVAYQVVAERPGHD
                                                                        .             

Mvan_5922|M.vanbaalenii_PYR-1       PIIPAPLIQDRRTGELLGVRYFGERQVIRALDPGFG-------------D
Mflv_4393|M.gilvum_PYR-GCK          PLLPAPLIQDRRTGELLGVRYYGERQTIRALDSRFG-------------D
MAB_4725|M.abscessus_ATCC_1997      LGLPPTLIRHRKSGELLAARYLGARQEIRVLDPDFG-------------P
MSMEG_5523|M.smegmatis_MC2_155      VMLPFPLILSEATGELIGARYYGERQVIHALDPQFA-------------A
Mb0466c|M.bovis_AF2122/97           SAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWR
Rv0457c|M.tuberculosis_H37Rv        SAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWR
MMAR_0779|M.marinum_M               TSDLHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWR
MAV_0727|M.avium_104                PTRQRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYA
MUL_0498|M.ulcerans_Agy99           PTRQRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYG
MLBr_02226|M.leprae_Br4923          PEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYG
TH_4519|M.thermoresistible__bu      LDEFVVSDDLSTVALLWNIDGASELQILQYADNTLS--------------
                                                   *           :                      

Mvan_5922|M.vanbaalenii_PYR-1       ILTNLENLSDGDVGRLSSDE--SGLRWVVGFNHDRDPGATYLYDHSTGES
Mflv_4393|M.gilvum_PYR-GCK          ILANLEKLSDGDLGNLSSDE--NGVRWIVGFNHDRDPGATYLYDHSTGES
MAB_4725|M.abscessus_ATCC_1997      VLEKLQELSDGDLAEVSSDE--DGRRWVVSFTHDRDPGVTYFYDHATGES
MSMEG_5523|M.smegmatis_MC2_155      VLEGVSRLNSGDIGSLSSDS--SGARWVVSFFSDRDPGVTYFYDHATGQS
Mb0466c|M.bovis_AF2122/97           REPLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DG
Rv0457c|M.tuberculosis_H37Rv        REPLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DG
MMAR_0779|M.marinum_M               REPIAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATT
MAV_0727|M.avium_104                RPEEISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGER
MUL_0498|M.ulcerans_Agy99           EVEDVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGER
MLBr_02226|M.leprae_Br4923          EPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGER
TH_4519|M.thermoresistible__bu      ---EPIPLPGMVAGELSISAG--GSMVAMTVESPWLPPTVELVDPRTRQW
                                                   :  .         :       *             

Mvan_5922|M.vanbaalenii_PYR-1       RLLFR-PMPHLDPEQLAPMRPVTITSRDGLALHSYLTLPVGVQPEGLPLV
Mflv_4393|M.gilvum_PYR-GCK          RLLFR-PLPQLDPSQLAPMRPVTITARDGLPLQSYLTLPVGVEAKSLPLV
MAB_4725|M.abscessus_ATCC_1997      HQLFR-PYPHLDPADLAPVVPVTITARDGLTLNSYLTLPVGTEPEGLPLV
MSMEG_5523|M.smegmatis_MC2_155      RKLFR-PHPHLDPDTLAPMTPVTIPARDGLDLPSYLTLPVGIPQENLPMV
Mb0466c|M.bovis_AF2122/97           RLAEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLL
Rv0457c|M.tuberculosis_H37Rv        RLAEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLL
MMAR_0779|M.marinum_M               QLEQIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSDGPGPTLL
MAV_0727|M.avium_104                TLLREQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIEFPAPALI
MUL_0498|M.ulcerans_Agy99           TLLREQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMI
MLBr_02226|M.leprae_Br4923          TLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVL
TH_4519|M.thermoresistible__bu      ELIDREPSTGPVTGTPTLER---LTARDGLELTGWLYRPPTGVQPVGAMI
                                          .                  : **  :   :           .::

Mvan_5922|M.vanbaalenii_PYR-1       LVVHGGPWYRDSWGFDAGVQMLANRGYAVLQVNFRGSLGYGKAFLKAAVG
Mflv_4393|M.gilvum_PYR-GCK          LVVHGGPWFRDSWGFDGHVQLLANRGYAVLQVNFRGSTGFGKAFLKAAIG
MAB_4725|M.abscessus_ATCC_1997      LVVHGGPWHRDSWGFDPTVQLLANRGYAVLQVNFRGSTGYGKAFTKAAIG
MSMEG_5523|M.smegmatis_MC2_155      LLVHGGPWARDCWYYQPEVQLLANRGYAVLQVNFRGSTGFGKAFTKAAIG
Mb0466c|M.bovis_AF2122/97           NGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMR
Rv0457c|M.tuberculosis_H37Rv        NGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMR
MMAR_0779|M.marinum_M               YGYGGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMR
MAV_0727|M.avium_104                YGYGAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKL
MUL_0498|M.ulcerans_Agy99           YAYGAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKL
MLBr_02226|M.leprae_Br4923          YGYGAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKL
TH_4519|M.thermoresistible__bu      FLHGGPEGQSRPGYN-EYFPPLLDRGITVFTPNVRGSGGFGRSFVHADDK
                                        .                   **      :.**.   *  :      

Mvan_5922|M.vanbaalenii_PYR-1       EFAGKMHDDLIDGVHWAVEQGYADPDRIAILGGSYGGYAALVGVTFTPDV
Mflv_4393|M.gilvum_PYR-GCK          EFAGKMHDDLIDGVNWAVEQGYADPDRVAILGGSYGGYAALVGVTFTPDV
MAB_4725|M.abscessus_ATCC_1997      EFAGKMHDDLIDAVDWAVEQGYADPGRIAIFGGSYGGYSALVGVTFTPDV
MSMEG_5523|M.smegmatis_MC2_155      EFAGKMHDDLIDAVDWAVKQGYADRDRVAIFGGSYGGYAALVGVTFTPDV
Mb0466c|M.bovis_AF2122/97           EGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEK
Rv0457c|M.tuberculosis_H37Rv        EGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEK
MMAR_0779|M.marinum_M               EGRHKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEK
MAV_0727|M.avium_104                LEKKNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPEL
MUL_0498|M.ulcerans_Agy99           LQKKNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPEL
MLBr_02226|M.leprae_Br4923          LEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDL
TH_4519|M.thermoresistible__bu      ENRFRAIDDVADCVHYLVRNGLAPADRIACAGWSYGGYLTQAALAFHPDL
                                        .   *.   .   *  . :   .:   * * **          *: 

Mvan_5922|M.vanbaalenii_PYR-1       FTAAVDYVGISDLANFMRTLPPIARPHLANNWHAYVGDPDDPEQLADMMA
Mflv_4393|M.gilvum_PYR-GCK          FAAAVDYVGISNLANFMRTLPPIARPQLANNWHAYVGDPDDPEQLADMMA
MAB_4725|M.abscessus_ATCC_1997      FAAAVDYVGISNLANFMRTLPPFVRPNLANNWYRYVGDPAVPEQEADMLA
MSMEG_5523|M.smegmatis_MC2_155      FAAAIDYVGISSLANFMRTLPDVARPFLANNWHRYVGDHDDPVQEADMLA
Mb0466c|M.bovis_AF2122/97           FGALVCDV---PLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISE
Rv0457c|M.tuberculosis_H37Rv        FGALVCDV---PLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISE
MMAR_0779|M.marinum_M               FGALVCNV---PLLDMKRYHLLLAGASWVAEYGDPDNPDD----WAFISE
MAV_0727|M.avium_104                FAGILAQV---PFVDPLTTILDPSLPLTVTEWDEWGNPLADKDVYFYMKS
MUL_0498|M.ulcerans_Agy99           FAGILAQV---PFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEVYAYMKS
MLBr_02226|M.leprae_Br4923          FTGILAQV---PFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKS
TH_4519|M.thermoresistible__bu      FAAGISVCGMSDLTTWYQTTEPWIAQSSYTEYGHPVADRD------LLER
                                    * . :       :                 ::               :  

Mvan_5922|M.vanbaalenii_PYR-1       RSPITKVDR--IRTPLLVIQGANDVRVVQAESDNLVAALRAR---GVEVD
Mflv_4393|M.gilvum_PYR-GCK          RSPITKVDQ--IRTPLFVIQGANDVRVVQAESDNLVNALRDR---GVEVD
MAB_4725|M.abscessus_ATCC_1997      RSPISRVDR--IRTPLLVAQGANDVRVVQAESDNIVAALRAR---GVEVE
MSMEG_5523|M.smegmatis_MC2_155      RSPITRVDQ--IRAPLLVIQGANDTRVVQAESDNLVEALRAR---GVEVE
Mb0466c|M.bovis_AF2122/97           YSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVW
Rv0457c|M.tuberculosis_H37Rv        YSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVW
MMAR_0779|M.marinum_M               YSPYQNISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVW
MAV_0727|M.avium_104                YSPYENVDA-RRYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFL
MUL_0498|M.ulcerans_Agy99           YSPYENVAD-RRYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVL
MLBr_02226|M.leprae_Br4923          YSPYENVEA-KQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVL
TH_4519|M.thermoresistible__bu      LSPLTHAAA--VTAPLLLVHGASDTNVPPSESIQMHTALERL---GRPVK
                                     **  .       ..::   .  * .*   .. :   **.     *  . 

Mvan_5922|M.vanbaalenii_PYR-1       YLIQADEGHGAVNPENVIEMWDAVARFLARHLGGRA--------------
Mflv_4393|M.gilvum_PYR-GCK          YLIQTDEGHGAVNAENTIEMWEAVVRFFARHIGGRA--------------
MAB_4725|M.abscessus_ATCC_1997      YMVKADEGHGFLNPENQIDLHRATERFLAQHVGGRQVS------------
MSMEG_5523|M.smegmatis_MC2_155      YMVKDDEGHGFVNPENRIDLFHAVERFLAEHL------------------
Mb0466c|M.bovis_AF2122/97           YYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG---------------
Rv0457c|M.tuberculosis_H37Rv        YYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG---------------
MMAR_0779|M.marinum_M               YYENIEGGHGGAADNEQLAFKSALSYSFLWRMLGSRK-------------
MAV_0727|M.avium_104                LKTQMNAGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPD
MUL_0498|M.ulcerans_Agy99           LKTQMNAGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG---------
MLBr_02226|M.leprae_Br4923          LKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGG
TH_4519|M.thermoresistible__bu      LLMFDDDGHEIVRRENRATLVEAMSHWLMSAFAERRREAS----------
                                           **     .       *                           

Mvan_5922|M.vanbaalenii_PYR-1       ---
Mflv_4393|M.gilvum_PYR-GCK          ---
MAB_4725|M.abscessus_ATCC_1997      ---
MSMEG_5523|M.smegmatis_MC2_155      ---
Mb0466c|M.bovis_AF2122/97           ---
Rv0457c|M.tuberculosis_H37Rv        ---
MMAR_0779|M.marinum_M               ---
MAV_0727|M.avium_104                PQG
MUL_0498|M.ulcerans_Agy99           ---
MLBr_02226|M.leprae_Br4923          AQG
TH_4519|M.thermoresistible__bu      ---