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MALPGLISVEDFFNPPTRAAATISPDGTRMAFLAPWKDRLNVWVQGLEPDADEPRCVTADDHRSVMHFEW TDDPRWLIYLQDTNGDENWHIHRVDLDDPDAAAVDLTPFPGAMAAPLREVRNGTTTVMLNNRDATLLDVH RLDIATGHLTLIATNPGHVNGWLCSDNGDVFATSLTPDGDVELSRWDSATDTLQPIARFDGSDYPVGIHP LVITPDGTGVWLGSHRDTDRSRLVRVDLVTGEETEADSHPELDIDPRAIVSPIIPAPLIQDRRTGELLGV RYFGERQVIRALDPGFGDILTNLENLSDGDVGRLSSDESGLRWVVGFNHDRDPGATYLYDHSTGESRLLF RPMPHLDPEQLAPMRPVTITSRDGLALHSYLTLPVGVQPEGLPLVLVVHGGPWYRDSWGFDAGVQMLANR GYAVLQVNFRGSLGYGKAFLKAAVGEFAGKMHDDLIDGVHWAVEQGYADPDRIAILGGSYGGYAALVGVT FTPDVFTAAVDYVGISDLANFMRTLPPIARPHLANNWHAYVGDPDDPEQLADMMARSPITKVDRIRTPLL VIQGANDVRVVQAESDNLVAALRARGVEVDYLIQADEGHGAVNPENVIEMWDAVARFLARHLGGRA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5922 | - | - | 100% (626) | peptidase S9 prolyl oligopeptidase |
M. vanbaalenii PYR-1 | Mvan_4095 | - | 4e-30 | 31.29% (310) | peptidase S9 prolyl oligopeptidase |
M. vanbaalenii PYR-1 | Mvan_3954 | - | 6e-21 | 24.75% (707) | peptidase S9 prolyl oligopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0466c | - | 5e-11 | 26.25% (259) | peptidase |
M. gilvum PYR-GCK | Mflv_4393 | - | 0.0 | 83.23% (626) | peptidase S9 prolyl oligopeptidase |
M. tuberculosis H37Rv | Rv0457c | - | 5e-11 | 26.25% (259) | peptidase |
M. leprae Br4923 | MLBr_02226 | ptrB | 5e-05 | 23.56% (191) | protease II |
M. abscessus ATCC 19977 | MAB_4725 | - | 0.0 | 67.78% (627) | peptidase |
M. marinum M | MMAR_0779 | - | 8e-19 | 30.27% (261) | peptidase |
M. avium 104 | MAV_0727 | - | 4e-09 | 25.27% (281) | protease 2 |
M. smegmatis MC2 155 | MSMEG_5523 | - | 0.0 | 66.61% (623) | peptidase |
M. thermoresistible (build 8) | TH_4519 | - | 3e-34 | 35.86% (251) | PUTATIVE peptidase S9, prolyl oligopeptidase active site domain |
M. ulcerans Agy99 | MUL_0498 | ptrB | 7e-11 | 25.38% (327) | protease II (oligopeptidase B), PtrB |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_5922|M.vanbaalenii_PYR-1 ------------------MALPGLISVEDFFNPPTRAAATISPDGTRMAF Mflv_4393|M.gilvum_PYR-GCK ------------------MALPDLIPVEDLFNPPTRAAAKISPDGTRMAF MAB_4725|M.abscessus_ATCC_1997 ------------------MGLPKLITVEEFFEPPVRTSASISPDGTMIAY MSMEG_5523|M.smegmatis_MC2_155 ------------------MPLPQPISVEDFFRPPVRAAAKISPDGTRIAY Mb0466c|M.bovis_AF2122/97 -----------MASMTFEP---APDGAD----PYLWLEDVTGAE--ALDW Rv0457c|M.tuberculosis_H37Rv --------------MTFEP---APDGAD----PYLWLEDVTGAE--ALDW MMAR_0779|M.marinum_M -----------MAPKAPEAPQ-APDAADTTTDPYLWLEDVTGEE--ALDW MAV_0727|M.avium_104 MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPD--VIAH MUL_0498|M.ulcerans_Agy99 MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVE--VIAH MLBr_02226|M.leprae_Br4923 MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPE--VVAY TH_4519|M.thermoresistible__bu ------------------VAEQVRATYGASLSPDATAFAHLVDDG---GF * : Mvan_5922|M.vanbaalenii_PYR-1 LAPWKDRLNVWVQG---LEPDADEPRCVTADDHRSVMHFEWTDDPRWLIY Mflv_4393|M.gilvum_PYR-GCK LAPSNNRLNVWVEN---LDPESGGLRRVTDDDNRSVLHFEWTDDPRWLIY MAB_4725|M.abscessus_ATCC_1997 LAPRKNRLNVWVQG---IG--STEARCVTHDETRSVTGFFWVDDPRWLLY MSMEG_5523|M.smegmatis_MC2_155 LAPWQNRLNIWVEN---VD--GSETRCVTADENRSIYIYEWTGDSRWLLY Mb0466c|M.bovis_AF2122/97 VRARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYN Rv0457c|M.tuberculosis_H37Rv VRARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYN MMAR_0779|M.marinum_M VRARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYD MAV_0727|M.avium_104 LEAESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYY MUL_0498|M.ulcerans_Agy99 LEAENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYY MLBr_02226|M.leprae_Br4923 LDAENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYY TH_4519|M.thermoresistible__bu PRAVQRFLRGWRAS---------SSRDVELPVVGPVRRVLHSPDGGWLAC . . : Mvan_5922|M.vanbaalenii_PYR-1 LQDTNGDENWHIHRVDLDDP---------------------DAAAVDLTP Mflv_4393|M.gilvum_PYR-GCK LQDTNGDENWHVHRVDLDDP---------------------EAPAVDLTP MAB_4725|M.abscessus_ATCC_1997 VQDSGGDENWHLYRVDLSTP---------------------DATAVDLTP MSMEG_5523|M.smegmatis_MC2_155 MQDTGGDEYFHVYRADPDDP---------------------AATAVDLTP Mb0466c|M.bovis_AF2122/97 FWRDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRAD Rv0457c|M.tuberculosis_H37Rv FWRDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRAD MMAR_0779|M.marinum_M FWRDANNPRGLWRRTTLES----------YRTDAPEWDVLIDVDELGRTD MAV_0727|M.avium_104 ARTYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVE--AE MUL_0498|M.ulcerans_Agy99 ARTFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEE--AE MLBr_02226|M.leprae_Br4923 SRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAE--AE TH_4519|M.thermoresistible__bu EVAPDGSDRSQIWVVTTDPD---------------------DRGAHRIDS Mvan_5922|M.vanbaalenii_PYR-1 FPGAMAAPLREVRN--GTTTVMLNNRDATLLDVHRLDIATGHLTLIATNP Mflv_4393|M.gilvum_PYR-GCK FPGAMALPVREVKN--GRTTVMVNNRDATLLDIHELDIATGDLTLIAKNP MAB_4725|M.abscessus_ATCC_1997 FPGARLLGLERPYGRSGKVYIQLNHRRIDQIDLYELDIASGELTMLAENP MSMEG_5523|M.smegmatis_MC2_155 FPGVRTS-FELLKGRPGKVMVQLNKRTSTLMDAAELDIATGELTELAQNP Mb0466c|M.bovis_AF2122/97 DQKWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQL Rv0457c|M.tuberculosis_H37Rv DQKWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQL MMAR_0779|M.marinum_M NKKWVWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFEL MAV_0727|M.avium_104 GHEFFALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EI MUL_0498|M.ulcerans_Agy99 GHDFFALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EI MLBr_02226|M.leprae_Br4923 GHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EI TH_4519|M.thermoresistible__bu WPPDAPEGAAELIAWDGNRIAAILTGQDGVGSSCLIDPADGSTVVLDRRS : * . Mvan_5922|M.vanbaalenii_PYR-1 GHVNGWLCSDNGDVFATSLTPD--------GDVELSRWDSATDTLQPIAR Mflv_4393|M.gilvum_PYR-GCK GHVNGWLSSDDGDLFATALTAD--------GDLELSRWDRDDEALRPIIR MAB_4725|M.abscessus_ATCC_1997 GGVMAWFCGPNHEVFAQSLTPG--------GDIEFSRYESGA--LRPLCV MSMEG_5523|M.smegmatis_MC2_155 GTVTNWQAGPNGDLFTSTQTAE--------GDIEIARWDSAAKTLRTIAT Mb0466c|M.bovis_AF2122/97 PPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETI Rv0457c|M.tuberculosis_H37Rv PPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETI MMAR_0779|M.marinum_M PEAKSQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMI MAV_0727|M.avium_104 ADIAAGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAGSGEA-PELV MUL_0498|M.ulcerans_Agy99 ADIGAGATWAADHRTVYYITVD-----AAWRPDTVWRYRLGSPGS-SERV MLBr_02226|M.leprae_Br4923 VGIGAGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLGSGQP-SEQV TH_4519|M.thermoresistible__bu GGRLVDAWAGAALIRVGPRGYRELIMLHGNTEMALLPSDPGSTTDFGVIL . Mvan_5922|M.vanbaalenii_PYR-1 FDGSDYPVGIHP---------LVITPDGTGVWLGSHRDTDRSRLVRVDLV Mflv_4393|M.gilvum_PYR-GCK FDGTDYPIGIHP---------LVLTPDGTGVWLGFNRGTDRTRLVHVDLA MAB_4725|M.abscessus_ATCC_1997 YDGADYPVGMNP---------TQMTPDGSGMWLGSSRDTDRTRLVRLDLA MSMEG_5523|M.smegmatis_MC2_155 YDGADYPLGIHP---------ISVSPDGTGLWFGSNKGTDRTRLVRLDVA Mb0466c|M.bovis_AF2122/97 FEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAP Rv0457c|M.tuberculosis_H37Rv FEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAP MMAR_0779|M.marinum_M FQGAHTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGTELIPLDVP MAV_0727|M.avium_104 YHEADEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLP MUL_0498|M.ulcerans_Agy99 YHEPDERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLP MLBr_02226|M.leprae_Br4923 YHEADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLP TH_4519|M.thermoresistible__bu DDHSARRLRRGPDGE------LTKLYQPAKRYPRESTEGYVRALIRSDNG . . . . Mvan_5922|M.vanbaalenii_PYR-1 TGEE----------------------------TEADSHPELDIDPRAIVS Mflv_4393|M.gilvum_PYR-GCK TGEE----------------------------TDVDSHPTFDVDPRAAVS MAB_4725|M.abscessus_ATCC_1997 TGAE----------------------------STIDSHPAYDLAA----A MSMEG_5523|M.smegmatis_MC2_155 TGEE----------------------------TEVDSHPSFDLAT----Q Mb0466c|M.bovis_AF2122/97 TDAS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAG Rv0457c|M.tuberculosis_H37Rv TDAS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAG MMAR_0779|M.marinum_M TDASSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSG MAV_0727|M.avium_104 RRDG-VEYSVEHA---VVGGQD------RFLILHNDGAVNFTLTEAPVSD MUL_0498|M.ulcerans_Agy99 RREG-VEYSVEHA---VIGGQD------RFLILHNDGAVNFTLVEAPVDD MLBr_02226|M.leprae_Br4923 RRDG-IEYSVEHAPSGLVGGQD------RFLILHNDGAVNFTLVESPVSN TH_4519|M.thermoresistible__bu AGYA----------------------RLLEVTTTADGVAYQVVAERPGHD . Mvan_5922|M.vanbaalenii_PYR-1 PIIPAPLIQDRRTGELLGVRYFGERQVIRALDPGFG-------------D Mflv_4393|M.gilvum_PYR-GCK PLLPAPLIQDRRTGELLGVRYYGERQTIRALDSRFG-------------D MAB_4725|M.abscessus_ATCC_1997 LGLPPTLIRHRKSGELLAARYLGARQEIRVLDPDFG-------------P MSMEG_5523|M.smegmatis_MC2_155 VMLPFPLILSEATGELIGARYYGERQVIHALDPQFA-------------A Mb0466c|M.bovis_AF2122/97 SAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWR Rv0457c|M.tuberculosis_H37Rv SAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWR MMAR_0779|M.marinum_M TSDLHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWR MAV_0727|M.avium_104 PTRQRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYA MUL_0498|M.ulcerans_Agy99 PTRQRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYG MLBr_02226|M.leprae_Br4923 PEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYG TH_4519|M.thermoresistible__bu LDEFVVSDDLSTVALLWNIDGASELQILQYADNTLS-------------- * : Mvan_5922|M.vanbaalenii_PYR-1 ILTNLENLSDGDVGRLSSDE--SGLRWVVGFNHDRDPGATYLYDHSTGES Mflv_4393|M.gilvum_PYR-GCK ILANLEKLSDGDLGNLSSDE--NGVRWIVGFNHDRDPGATYLYDHSTGES MAB_4725|M.abscessus_ATCC_1997 VLEKLQELSDGDLAEVSSDE--DGRRWVVSFTHDRDPGVTYFYDHATGES MSMEG_5523|M.smegmatis_MC2_155 VLEGVSRLNSGDIGSLSSDS--SGARWVVSFFSDRDPGVTYFYDHATGQS Mb0466c|M.bovis_AF2122/97 REPLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DG Rv0457c|M.tuberculosis_H37Rv REPLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DG MMAR_0779|M.marinum_M REPIAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATT MAV_0727|M.avium_104 RPEEISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGER MUL_0498|M.ulcerans_Agy99 EVEDVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGER MLBr_02226|M.leprae_Br4923 EPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGER TH_4519|M.thermoresistible__bu ---EPIPLPGMVAGELSISAG--GSMVAMTVESPWLPPTVELVDPRTRQW : . : * Mvan_5922|M.vanbaalenii_PYR-1 RLLFR-PMPHLDPEQLAPMRPVTITSRDGLALHSYLTLPVGVQPEGLPLV Mflv_4393|M.gilvum_PYR-GCK RLLFR-PLPQLDPSQLAPMRPVTITARDGLPLQSYLTLPVGVEAKSLPLV MAB_4725|M.abscessus_ATCC_1997 HQLFR-PYPHLDPADLAPVVPVTITARDGLTLNSYLTLPVGTEPEGLPLV MSMEG_5523|M.smegmatis_MC2_155 RKLFR-PHPHLDPDTLAPMTPVTIPARDGLDLPSYLTLPVGIPQENLPMV Mb0466c|M.bovis_AF2122/97 RLAEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLL Rv0457c|M.tuberculosis_H37Rv RLAEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLL MMAR_0779|M.marinum_M QLEQIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSDGPGPTLL MAV_0727|M.avium_104 TLLREQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIEFPAPALI MUL_0498|M.ulcerans_Agy99 TLLREQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMI MLBr_02226|M.leprae_Br4923 TLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVL TH_4519|M.thermoresistible__bu ELIDREPSTGPVTGTPTLER---LTARDGLELTGWLYRPPTGVQPVGAMI . : ** : : .:: Mvan_5922|M.vanbaalenii_PYR-1 LVVHGGPWYRDSWGFDAGVQMLANRGYAVLQVNFRGSLGYGKAFLKAAVG Mflv_4393|M.gilvum_PYR-GCK LVVHGGPWFRDSWGFDGHVQLLANRGYAVLQVNFRGSTGFGKAFLKAAIG MAB_4725|M.abscessus_ATCC_1997 LVVHGGPWHRDSWGFDPTVQLLANRGYAVLQVNFRGSTGYGKAFTKAAIG MSMEG_5523|M.smegmatis_MC2_155 LLVHGGPWARDCWYYQPEVQLLANRGYAVLQVNFRGSTGFGKAFTKAAIG Mb0466c|M.bovis_AF2122/97 NGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMR Rv0457c|M.tuberculosis_H37Rv NGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMR MMAR_0779|M.marinum_M YGYGGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMR MAV_0727|M.avium_104 YGYGAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKL MUL_0498|M.ulcerans_Agy99 YAYGAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKL MLBr_02226|M.leprae_Br4923 YGYGAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKL TH_4519|M.thermoresistible__bu FLHGGPEGQSRPGYN-EYFPPLLDRGITVFTPNVRGSGGFGRSFVHADDK . ** :.**. * : Mvan_5922|M.vanbaalenii_PYR-1 EFAGKMHDDLIDGVHWAVEQGYADPDRIAILGGSYGGYAALVGVTFTPDV Mflv_4393|M.gilvum_PYR-GCK EFAGKMHDDLIDGVNWAVEQGYADPDRVAILGGSYGGYAALVGVTFTPDV MAB_4725|M.abscessus_ATCC_1997 EFAGKMHDDLIDAVDWAVEQGYADPGRIAIFGGSYGGYSALVGVTFTPDV MSMEG_5523|M.smegmatis_MC2_155 EFAGKMHDDLIDAVDWAVKQGYADRDRVAIFGGSYGGYAALVGVTFTPDV Mb0466c|M.bovis_AF2122/97 EGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEK Rv0457c|M.tuberculosis_H37Rv EGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEK MMAR_0779|M.marinum_M EGRHKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEK MAV_0727|M.avium_104 LEKKNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPEL MUL_0498|M.ulcerans_Agy99 LQKKNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPEL MLBr_02226|M.leprae_Br4923 LEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDL TH_4519|M.thermoresistible__bu ENRFRAIDDVADCVHYLVRNGLAPADRIACAGWSYGGYLTQAALAFHPDL . *. . * . : .: * * ** *: Mvan_5922|M.vanbaalenii_PYR-1 FTAAVDYVGISDLANFMRTLPPIARPHLANNWHAYVGDPDDPEQLADMMA Mflv_4393|M.gilvum_PYR-GCK FAAAVDYVGISNLANFMRTLPPIARPQLANNWHAYVGDPDDPEQLADMMA MAB_4725|M.abscessus_ATCC_1997 FAAAVDYVGISNLANFMRTLPPFVRPNLANNWYRYVGDPAVPEQEADMLA MSMEG_5523|M.smegmatis_MC2_155 FAAAIDYVGISSLANFMRTLPDVARPFLANNWHRYVGDHDDPVQEADMLA Mb0466c|M.bovis_AF2122/97 FGALVCDV---PLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISE Rv0457c|M.tuberculosis_H37Rv FGALVCDV---PLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISE MMAR_0779|M.marinum_M FGALVCNV---PLLDMKRYHLLLAGASWVAEYGDPDNPDD----WAFISE MAV_0727|M.avium_104 FAGILAQV---PFVDPLTTILDPSLPLTVTEWDEWGNPLADKDVYFYMKS MUL_0498|M.ulcerans_Agy99 FAGILAQV---PFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEVYAYMKS MLBr_02226|M.leprae_Br4923 FTGILAQV---PFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKS TH_4519|M.thermoresistible__bu FAAGISVCGMSDLTTWYQTTEPWIAQSSYTEYGHPVADRD------LLER * . : : :: : Mvan_5922|M.vanbaalenii_PYR-1 RSPITKVDR--IRTPLLVIQGANDVRVVQAESDNLVAALRAR---GVEVD Mflv_4393|M.gilvum_PYR-GCK RSPITKVDQ--IRTPLFVIQGANDVRVVQAESDNLVNALRDR---GVEVD MAB_4725|M.abscessus_ATCC_1997 RSPISRVDR--IRTPLLVAQGANDVRVVQAESDNIVAALRAR---GVEVE MSMEG_5523|M.smegmatis_MC2_155 RSPITRVDQ--IRAPLLVIQGANDTRVVQAESDNLVEALRAR---GVEVE Mb0466c|M.bovis_AF2122/97 YSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVW Rv0457c|M.tuberculosis_H37Rv YSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVW MMAR_0779|M.marinum_M YSPYQNISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVW MAV_0727|M.avium_104 YSPYENVDA-RRYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFL MUL_0498|M.ulcerans_Agy99 YSPYENVAD-RRYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVL MLBr_02226|M.leprae_Br4923 YSPYENVEA-KQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVL TH_4519|M.thermoresistible__bu LSPLTHAAA--VTAPLLLVHGASDTNVPPSESIQMHTALERL---GRPVK ** . ..:: . * .* .. : **. * . Mvan_5922|M.vanbaalenii_PYR-1 YLIQADEGHGAVNPENVIEMWDAVARFLARHLGGRA-------------- Mflv_4393|M.gilvum_PYR-GCK YLIQTDEGHGAVNAENTIEMWEAVVRFFARHIGGRA-------------- MAB_4725|M.abscessus_ATCC_1997 YMVKADEGHGFLNPENQIDLHRATERFLAQHVGGRQVS------------ MSMEG_5523|M.smegmatis_MC2_155 YMVKDDEGHGFVNPENRIDLFHAVERFLAEHL------------------ Mb0466c|M.bovis_AF2122/97 YYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG--------------- Rv0457c|M.tuberculosis_H37Rv YYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG--------------- MMAR_0779|M.marinum_M YYENIEGGHGGAADNEQLAFKSALSYSFLWRMLGSRK------------- MAV_0727|M.avium_104 LKTQMNAGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPD MUL_0498|M.ulcerans_Agy99 LKTQMNAGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG--------- MLBr_02226|M.leprae_Br4923 LKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGG TH_4519|M.thermoresistible__bu LLMFDDDGHEIVRRENRATLVEAMSHWLMSAFAERRREAS---------- ** . * Mvan_5922|M.vanbaalenii_PYR-1 --- Mflv_4393|M.gilvum_PYR-GCK --- MAB_4725|M.abscessus_ATCC_1997 --- MSMEG_5523|M.smegmatis_MC2_155 --- Mb0466c|M.bovis_AF2122/97 --- Rv0457c|M.tuberculosis_H37Rv --- MMAR_0779|M.marinum_M --- MAV_0727|M.avium_104 PQG MUL_0498|M.ulcerans_Agy99 --- MLBr_02226|M.leprae_Br4923 AQG TH_4519|M.thermoresistible__bu ---