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M. leprae Br4923 MLBr_02226 (ptrB)

annotation: protease II
coordinates: 2642785 - 2644959
length: 724

TKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNE
IKARTKENDLSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAE
GHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLD
ESRRPDTVWRCRLGSGQPSEQVYHEADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVV
LPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLVESPVSNPEQQRTLIPHRDDVRLDSADAFAGY
LVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDL
ATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYGAYEICVDPSFS
IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAG
GLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEA
KQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLL
AAVDVDQYGTATEVDDLGGGAQG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02226ptrB-100% (724)protease II

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0804ptrB0.077.87% (714) protease II PrtB
M. gilvum PYR-GCKMflv_1617-0.070.20% (708) oligopeptidase B
M. tuberculosis H37RvRv0782ptrBb0.077.84% (519) oligopeptidase B
M. abscessus ATCC 19977MAB_0690-0.063.32% (698) protease II
M. marinum MMMAR_4908ptrB0.075.89% (701) protease II (oligopeptidase B), PtrB
M. avium 104MAV_0727-0.075.55% (724) protease 2
M. smegmatis MC2 155MSMEG_5839-0.072.43% (711) protease 2
M. thermoresistible (build 8)TH_1817ptrBa0.072.62% (705) PROBABLE PROTEASE II PTRBB
M. ulcerans Agy99MUL_0498ptrB0.075.46% (701) protease II (oligopeptidase B), PtrB
M. vanbaalenii PYR-1Mvan_5137-0.071.47% (708) oligopeptidase B

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1617|M.gilvum_PYR-GCK          ------MSGDVTAPIAKRVDTRREHHGDVFVDPYEWLRDKENSDVVDYLK
Mvan_5137|M.vanbaalenii_PYR-1       -MKPSEMAG-PPAPIAKRIDTRREHHGDVFIDPYEWLRDKDNREVVDYLE
MSMEG_5839|M.smegmatis_MC2_155      ----MSEQQPVEPPVAKRLNHRREYHGDVFIDPYEWLRDKDDPEVIGYLE
TH_1817|M.thermoresistible__bu      -MDRTLSMTQINPPVAKRVEHRREHHGDVFIDPYEWLRDKSDPDVIAHLE
Mb0804|M.bovis_AF2122/97            ---MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLE
Rv0782|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4908|M.marinum_M               ------MTDHTLPPVAKRIETRREHHGDVFVDPYEWLRDKDSVEVIAHLE
MUL_0498|M.ulcerans_Agy99           MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVEVIAHLE
MLBr_02226|M.leprae_Br4923          --MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLD
MAV_0727|M.avium_104                --MTETHLATSVPPVAKRVDTRREHHGDVFVDPYEWLREKTDPDVIAHLE
MAB_0690|M.abscessus_ATCC_1997      ------MSGPVRPPVANRIDTLREYHGDTFVDPYEWMREKETPEVIAYLE
                                                                                      

Mflv_1617|M.gilvum_PYR-GCK          AENAFTEHVTEALAPLRQKIFDEIKARTKETDLSVPTRRGDWWYYGRSFQ
Mvan_5137|M.vanbaalenii_PYR-1       AENAFTEHVTEKLAPLRQQIFDEIKARTKETDLSVPTRRGDWWYYGRSFQ
MSMEG_5839|M.smegmatis_MC2_155      AENAYTASVTAHLEPLRQKIFDEIKARTKETDLSVPMRRGPWWYYARSFE
TH_1817|M.thermoresistible__bu      AENDYTEQVTAHLEPLRRQIFEEIKSRTKETDLSVPVRRGDWWYYARSFE
Mb0804|M.bovis_AF2122/97            AENDYTERTTAHLEPLRQKIFHEIKARTKETDLSVPTRRGNWWYYARTFE
Rv0782|M.tuberculosis_H37Rv         ----------------------------MTNDIPCGSR------------
MMAR_4908|M.marinum_M               AENTYTDQTTAHLEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYARTFE
MUL_0498|M.ulcerans_Agy99           AENTYTDQTTAHLEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYARTFE
MLBr_02226|M.leprae_Br4923          AENDYVNQMTAHLEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSRTFE
MAV_0727|M.avium_104                AESDYADRMTAHLAPLRQQIFDEIKARTKETDLSVPTRQGRWWYYARTYE
MAB_0690|M.abscessus_ATCC_1997      AENAYVDDQLGHLAELRTTIFGEIKSRTKETDLSIPTRMGQWWYYARSFE
                                                                  .*:.   *            

Mflv_1617|M.gilvum_PYR-GCK          GKQYGVQCRCPVDDPEDWTPPELDENTEIPGEQVLLDENVEAEGHDFFSL
Mvan_5137|M.vanbaalenii_PYR-1       GKQYGVQCRCPVTDPDDWTPPQFDENTEIPGEQVLLDENVEAEGHDFFSL
MSMEG_5839|M.smegmatis_MC2_155      GKQYAVHCRCPVSDPDDWTPPTFDEHTEVPGEQILLDENVEADGHEYFAL
TH_1817|M.thermoresistible__bu      GKQYGVHCRCPVADSDDWTPPQFDEHTEIPGEQVLLDENVEAEGHSFFAL
Mb0804|M.bovis_AF2122/97            GKQYGVHCRCPVTDPDDWNPPEFDERTEIPGEQLLLDENVEADGHDFFAL
Rv0782|M.tuberculosis_H37Rv         -----------------IYAPENSTRTRSPG-------------------
MMAR_4908|M.marinum_M               GRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEEAEGHDFFAL
MUL_0498|M.ulcerans_Agy99           GRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEEAEGHDFFAL
MLBr_02226|M.leprae_Br4923          GKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFAL
MAV_0727|M.avium_104                GKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVEAEGHEFFAL
MAB_0690|M.abscessus_ATCC_1997      GKQYGVHCRCPIGDPNDWTPPALDH--DVPGEQILLDGNVEAAGHDFFSL
                                                       .*        .*                   

Mflv_1617|M.gilvum_PYR-GCK          GAASVSVDGNILAYSVDVKGDERYTLRFKDLRTGKRYDDEITGIGAGVTW
Mvan_5137|M.vanbaalenii_PYR-1       GAATVSVDGNILAYSVDVKGDERYTLRFKDLRTGQRYDDEIVGIGAGATW
MSMEG_5839|M.smegmatis_MC2_155      GAATVSLDGNTLAYSVDVLGDERYTLRFKDLHTGELYDDTITGIGAGGIW
TH_1817|M.thermoresistible__bu      GAATVSLDGNTLAYSVDVVGDERYTLRFKDLRTGQMYDDTITGIAAGATW
Mb0804|M.bovis_AF2122/97            GAASVSLDDNLLAYSVDVVGDERYTLRFKDLRTGEQYPDEIAGIGAGVTW
Rv0782|M.tuberculosis_H37Rv         --------------------------------SERESPGQLT--------
MMAR_4908|M.marinum_M               GAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPDEIADIGAGATW
MUL_0498|M.ulcerans_Agy99           GAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPDEIADIGAGATW
MLBr_02226|M.leprae_Br4923          GTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATW
MAV_0727|M.avium_104                GAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPDEIADIAAGATW
MAB_0690|M.abscessus_ATCC_1997      GAATVSPDGNTLAYSVDVVGHEMYTLRFKNLRTGEMYPDEIADIGAGATW
                                                                    : .   . :.        

Mflv_1617|M.gilvum_PYR-GCK          AADNATVYYVTVDDAWRPDTVWRHRLGSGQPAQRVYHEPDERYWIGVGRT
Mvan_5137|M.vanbaalenii_PYR-1       AADNNTVYYVTVDEAWRPDTVWRHRLGSGLPAERVHHEPDERFWVAVGRT
MSMEG_5839|M.smegmatis_MC2_155      AADNRTFYYTTVDDAWRPDTVWRHRLGAGLPGERVYHEPDERFWVGIGRS
TH_1817|M.thermoresistible__bu      AADNRTIYYTTVDAAWRPDRIWRHRLGSGDDAELVYHEPDERFWLGVGRT
Mb0804|M.bovis_AF2122/97            AADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRFWLAVGRT
Rv0782|M.tuberculosis_H37Rv         ----TTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRFWLAVGRT
MMAR_4908|M.marinum_M               AADHRTVYYITVDAAWRPDTVWRYRLGSPGSSERVYHEPDERFWLGVGRT
MUL_0498|M.ulcerans_Agy99           AADHRTVYYITVDAAWRPDTVWRYRLGSPGSSERVYHEPDERFWLGVGRT
MLBr_02226|M.leprae_Br4923          AADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADERFWLAVGLS
MAV_0727|M.avium_104                AADNRTVYYLTLDAAHRPDKVWRYRAGSGEAPELVYHEADEKFWLGVGLT
MAB_0690|M.abscessus_ATCC_1997      AMDSRTLYYPVIDEAFRPYAIRRYTLGGGAEPVEVFSEPDERFWIGVGRT
                                         *.** .:* : **  : *   *.      *. *.*:::*:.:* :

Mflv_1617|M.gilvum_PYR-GCK          RSNKYVIIAAGSAVTSELRYGDAEDGDTDFTVVWPRRDGVEYSIEHA---
Mvan_5137|M.vanbaalenii_PYR-1       RSNKYVIIAAGSAVTSELRYADAADPQAEFTTVWPRRDSVEYSLDHA---
MSMEG_5839|M.smegmatis_MC2_155      RSDKYVFIAAGSAVTSEVRYGDATDPQAEFTSVWGRRDLVEYSVEHA---
TH_1817|M.thermoresistible__bu      RSDKYVMIVAGSAVTSEVRYADAADPNAEFTVIWPRRDRVEYSVEHA---
Mb0804|M.bovis_AF2122/97            RSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHA---
Rv0782|M.tuberculosis_H37Rv         RSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHA---
MMAR_4908|M.marinum_M               RSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRREGVEYSVEHA---
MUL_0498|M.ulcerans_Agy99           RSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRREGVEYSVEHA---
MLBr_02226|M.leprae_Br4923          RSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSG
MAV_0727|M.avium_104                RSEAYVMIASGSSITSEFRYADAADPHAQFTVVLPRRDGVEYSVEHA---
MAB_0690|M.abscessus_ATCC_1997      RSDRFVAISVHSSVTSEILIGDAEDPAATFSPVWLRRNGIEYTVDHI---
                                    **: :: *   *::***   ..: :  : *: :  **: :**:::*    

Mflv_1617|M.gilvum_PYR-GCK          VVGGQDRFLILHNDGAENFTLVEAPVADPTD-------VTTLIEHREDVR
Mvan_5137|M.vanbaalenii_PYR-1       VVGGEDRFLILHNDGAENFTLVEVPVAEPTD-------VRTLIEHRSDVR
MSMEG_5839|M.smegmatis_MC2_155      VVGGEDRFLILHNDGAENFTLVDAPVSDPND-------FRTLIAHRDDVR
TH_1817|M.thermoresistible__bu      VIGGEDRFLILHNDGAVNFTLVEVPVADPAPDSGR---VRTLIEHRDDVR
Mb0804|M.bovis_AF2122/97            VIAGQDRFLILHNDGAVNFTLVEAPVEDPAR-------QRTLIAHRDDVR
Rv0782|M.tuberculosis_H37Rv         VIAGQDRFLILHNDGAVNFTLVEAPVEDPAR-------QRTLIAHRDDVR
MMAR_4908|M.marinum_M               VIGGQDRFLILHNDGAVNFTLVEAPVDDPTR-------QRTLIPHREDVR
MUL_0498|M.ulcerans_Agy99           VIGGQDRFLILHNDGAVNFTLVEAPVDDPTR-------QRTLIPHREDVR
MLBr_02226|M.leprae_Br4923          LVGGQDRFLILHNDGAVNFTLVESPVSNPEQ-------QRTLIPHRDDVR
MAV_0727|M.avium_104                VVGGQDRFLILHNDGAVNFTLTEAPVSDPTR-------QRTLIPHRDDVR
MAB_0690|M.abscessus_ATCC_1997      VVGGEDRLLILHNDGAVNFALAEMPVAAVVDGPADPSAARTLIAHRDDVR
                                    ::.*:**:******** **:*.: **              *** **.***

Mflv_1617|M.gilvum_PYR-GCK          LDAVDAFDGHLVLSYREDALPRIQLWPVTDTG-YGRAQDITFDSELMSVG
Mvan_5137|M.vanbaalenii_PYR-1       LDSIDAFAGHLVVSYRKDALPCIQLWPVSDTG-YGDPQDITFDSELMSVG
MSMEG_5839|M.smegmatis_MC2_155      LDAVDAFDGFLVVSYRSEALPKIQLWPIDANGEYGRAQEITFASELTAAG
TH_1817|M.thermoresistible__bu      LDAVDAFANHLVVSYRGEALPRIQLWPIRDDGSYGTPEEITFDTELTSAG
Mb0804|M.bovis_AF2122/97            LDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAG
Rv0782|M.tuberculosis_H37Rv         LDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAG
MMAR_4908|M.marinum_M               LDGVDAFAAHLVVSYRIEALPRIQLWPLSADGDYGEVEDVVFDSELMSAG
MUL_0498|M.ulcerans_Agy99           LDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYGEVEDVVFDSELMSAG
MLBr_02226|M.leprae_Br4923          LDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVS
MAV_0727|M.avium_104                LDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYARPEEISFDSELMSAG
MAB_0690|M.abscessus_ATCC_1997      LDGVEAFAQRFVIGYRREALPRIQVWPVTADG-YGSPQEVEFDSELMLSG
                                    **. :*:   :*:.**  *** :*:* :   * *.  ::: * :**   .

Mflv_1617|M.gilvum_PYR-GCK          LSANPNWSAPKLRIGATSFVTPVRIYDLDLATGERTLLREQPVLGDYRPE
Mvan_5137|M.vanbaalenii_PYR-1       LSANPNWSAPKMRIGATSFITPVRVYDLDLATGERTLLREQPVLGDYHPE
MSMEG_5839|M.smegmatis_MC2_155      LAGNPNWSTPKLRIAATSFITPARVYDLDLATGERTLLREQPVLGGYRPE
TH_1817|M.thermoresistible__bu      LSANPNWAAPKLRVGVTSFITPVRVYDIDLATGERTLLREQPVLGGYRPE
Mb0804|M.bovis_AF2122/97            LGPNPNWDSPKLRVGAGSFVTPVRIYDIDLVTGERTLLKEQPVLGGYRRE
Rv0782|M.tuberculosis_H37Rv         LGPNPNWDSPKLRVGAGSFVTPVRIYDIDLVTGERTLLKEQPVLGGYRRE
MMAR_4908|M.marinum_M               LGANPNWDCPKLRVGAGSFITPVRIYDIDLRTGERTLLREQPVLGGYRRE
MUL_0498|M.ulcerans_Agy99           LGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGERTLLREQPVLGGYRRE
MLBr_02226|M.leprae_Br4923          LEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHE
MAV_0727|M.avium_104                LAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGERTLLREQPVLGDYRPA
MAB_0690|M.abscessus_ATCC_1997      LGDNPEWDSPLLRVGCASFITPTRVYDLDVHTGERTLLKEQPVLGGYRRE
                                    *  *.:*  * :*:   *:: *.*:**:*. *******:******.*:  

Mflv_1617|M.gilvum_PYR-GCK          DYVERRDWAVAEDGARVPISIVHRAGVQFPAPAMLYGYGAYESCEDPRFS
Mvan_5137|M.vanbaalenii_PYR-1       DYVERRDWAIAEDGARVPISVVHRAGLEGPAPLLLYGYGAYEACEDPRFS
MSMEG_5839|M.smegmatis_MC2_155      DYVERRDWVIAEDGARVPISIVHRAGVQFPAPTLLYGYGAYESCEDPRFS
TH_1817|M.thermoresistible__bu      DYVERRDWAIAPDGARIPVSIVHRAGAQFPAPTLLYGYGSYEACEDPRFS
Mb0804|M.bovis_AF2122/97            DYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEICEDPRFS
Rv0782|M.tuberculosis_H37Rv         DYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEICEDPRFS
MMAR_4908|M.marinum_M               DYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMIYGYGAYEICEDPRFS
MUL_0498|M.ulcerans_Agy99           DYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMIYAYGAYEICEDPRFS
MLBr_02226|M.leprae_Br4923          DYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYGAYEICVDPSFS
MAV_0727|M.avium_104                DYVERRDWAVADDGTRVPVSIVHRADIEFPAPALIYGYGAYEICIDPSFS
MAB_0690|M.abscessus_ATCC_1997      DYVERREWALAVDGTRVPLSVVHRRGITSPSPTVLYGYGAYEMCEDPQFS
                                    ******:*. . **: :*:*:*:*     *:* ::*.**:** * ** **

Mflv_1617|M.gilvum_PYR-GCK          IARLSLLDRGMVFAVAHVRGGGELGRPWYEHGKMLEKRNTFTDFIAVARH
Mvan_5137|M.vanbaalenii_PYR-1       IARLSLLDRGMIFAVAHVRGGGELGRPWYEHGKLLEKRNTFTDFASVGRH
MSMEG_5839|M.smegmatis_MC2_155      IARLSLLDRGMVFAIAHVRGGGELGRSWYEHGKLLEKKNTFTDFIAVARH
TH_1817|M.thermoresistible__bu      IARLSLLDRGMVFAVAHVRGGGEMGRPWYEHGKMLEKKNSFTDFIAVAEH
Mb0804|M.bovis_AF2122/97            IARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARH
Rv0782|M.tuberculosis_H37Rv         IARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARH
MMAR_4908|M.marinum_M               IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLLQKKNTFTDFIAVAEH
MUL_0498|M.ulcerans_Agy99           IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLLQKKNTFTDFIAVAEH
MLBr_02226|M.leprae_Br4923          IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKH
MAV_0727|M.avium_104                IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFVSAARH
MAB_0690|M.abscessus_ATCC_1997      IGRLSLLDRGVVFVIAHVRGGGEMGRLWYEDGKMLHKKHSFSDFVSAARH
                                    * ********::*.:********:** ***.**:*.*:::*:** :...*

Mflv_1617|M.gilvum_PYR-GCK          LDENGTVRPENLVAYGGSAGGLLVGAVANMAPERFAGILAAVPFVDPLTT
Mvan_5137|M.vanbaalenii_PYR-1       LVDTGTTRPENMVAYGGSAGGLLMGAVANMAPDLFAGILATVPFVDPLTT
MSMEG_5839|M.smegmatis_MC2_155      LIDQGLTRPQNLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDALTT
TH_1817|M.thermoresistible__bu      LIDTGVTRPQNLVAYGGSAGGLLVGAVANMAPQLFAGVLAQVPFVDPLTT
Mb0804|M.bovis_AF2122/97            LVDTGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTT
Rv0782|M.tuberculosis_H37Rv         LVDTGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTT
MMAR_4908|M.marinum_M               LVESGLTQPERLVALGGSAGGLLMGAVANMAPELFAGILAQVPFVDPLTT
MUL_0498|M.ulcerans_Agy99           LVESGLTQPERLVALGGSAGGLLMGAVANMAPELFAGILAQVPFVDPLTT
MLBr_02226|M.leprae_Br4923          LVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTGILAQVPFVDPLTT
MAV_0727|M.avium_104                LVESNVTRPDRLVALGGSAGGLLVGAVANLAPELFAGILAQVPFVDPLTT
MAB_0690|M.abscessus_ATCC_1997      LVDSGVALPNRLVAWGGSAGGLLVGAAVNLAPELFAGVLAQVPFVDPVTT
                                    * : . .  :.:** ********:*...*:**: *:*:** *****.:**

Mflv_1617|M.gilvum_PYR-GCK          ILDPSLPLTVTEWDEWGNPLDDPEVYRYMKSYSPYENVSPANYPSILAMT
Mvan_5137|M.vanbaalenii_PYR-1       ILDPSLPLTVTEWDEWGNPLEDPEVYAYMKSYSPYENVESRNYPAILAMT
MSMEG_5839|M.smegmatis_MC2_155      ILDPSLPLTVTEWDEWGNPLEDPEVYRYMKSYSPYENVTTQDYPPILAMT
TH_1817|M.thermoresistible__bu      ILDPSLPLTVTEWDEWGNPLEDKEVYEYMKSYSPYENVTAQDYPAILAMT
Mb0804|M.bovis_AF2122/97            ILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMT
Rv0782|M.tuberculosis_H37Rv         ILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMT
MMAR_4908|M.marinum_M               ILDPSLPLTVTEWDEWGNPLSDSEVYAYMKSYSPYENVADRRYPAILAMT
MUL_0498|M.ulcerans_Agy99           ILDPSLPLTVTEWDEWGNPLSDSEVYAYMKSYSPYENVADRRYPAILAMT
MLBr_02226|M.leprae_Br4923          MLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAMT
MAV_0727|M.avium_104                ILDPSLPLTVTEWDEWGNPLADKDVYFYMKSYSPYENVDARRYPAIMAMT
MAB_0690|M.abscessus_ATCC_1997      ICDPSLPLTVTEWDEWGNPLENKDVYDYIKSYSPYENIRAADYPSILAMT
                                    : ****************** : :.* *:********:    **.*:***

Mflv_1617|M.gilvum_PYR-GCK          SLNDTRVFYVEPAKWVAALRHAQKDPAAESARVLLKTEMNAGHGGISGRY
Mvan_5137|M.vanbaalenii_PYR-1       SLNDTRVYYVEPAKWVAALRHAQTDPAADAVKVLLKTEMNAGHGGISGRY
MSMEG_5839|M.smegmatis_MC2_155      SLNDTRVYYVEPAKWVAALRHTKTD----NNPVLLKTEMVAGHGGLSGRY
TH_1817|M.thermoresistible__bu      SLNDTRVYYVEPAKWVAALRHHKTD----DRPVLLKTEMTAGHAGISGRY
Mb0804|M.bovis_AF2122/97            SLNDTRVYYVEPAKWVAALRHAKTD----GNSVLLKTQMHAGHGGISGRY
Rv0782|M.tuberculosis_H37Rv         SLNDTRVYYVEPAKWVAALRHAKTD----GNSVLLKTQMHAGHGGISGRY
MMAR_4908|M.marinum_M               SLNDTRVYFVEPAKWVAALRHANGD----GNQVLLKTQMNAGHGGISGRY
MUL_0498|M.ulcerans_Agy99           SLNDTRVYFVEPAKWVAALRHANGD----GNQVLLKTQMNAGHGGISGRY
MLBr_02226|M.leprae_Br4923          SLHDTRVHYVEPAKWIAALRHTKSD----GNPVLLKTQMAAGHAGISGRY
MAV_0727|M.avium_104                SLNDTRVYYVEPAKWVAALRHANPA----GGPFLLKTQMNAGHGGVSGRY
MAB_0690|M.abscessus_ATCC_1997      SLHDSRVLYVEPAKWVAELRHTTTG----ERPILLKTEMTAGHGGISGRY
                                    **:*:** :******:* ***           .****:* ***.*:****

Mflv_1617|M.gilvum_PYR-GCK          ERWKETAFQYAWLLDVAKAETGG--------------
Mvan_5137|M.vanbaalenii_PYR-1       ERWKETAFQFAWLLDAAKAGHDGGA------------
MSMEG_5839|M.smegmatis_MC2_155      ERWREAAFQYAWLLAAADRDQYGSGQVDALFGGPDT-
TH_1817|M.thermoresistible__bu      ERWKEVAFQYAWVLATADPENYDTGRAA---------
Mb0804|M.bovis_AF2122/97            ERWKETAFQYGWLLATADSDRYGGG-QGNDLDGAAPA
Rv0782|M.tuberculosis_H37Rv         ERWKETAFQYGWLLATADSDRYGGG-QGNDLDGAAPA
MMAR_4908|M.marinum_M               ERWKETAFQYAWLLAAAGCDDSGGG------------
MUL_0498|M.ulcerans_Agy99           ERWKETAFQSAWLLAAAGCDDSGGG------------
MLBr_02226|M.leprae_Br4923          KAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG
MAV_0727|M.avium_104                KAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPDPQG
MAB_0690|M.abscessus_ATCC_1997      ERWKESAFQLAWLLDILGAQGETPNAR----------
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