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AEQVRRIYGASMSPDATAFAHLVDDGGYPRAVQRFLRGWRASSSRDVELPVEGPVTRVMHSADGHWLACQ VAPEGGSRSQIWVVTTDPDDRDARRIDRWPSGVEGTAELISWDGTLVAAILTGEDGVGTSCLLDPSGTTV IVLDRRSGGRLVDAWGGASLVRVGPRGYRDLIMLRALTETALLPYDPGSTTDTGIILDDHSPRRLRSGPE GETTDLYYPVKDYGLDSTEGYVRALIRSENGAQHARLLEVTVTADGVSYQVVAERPGYELDEFTVSDDLS TVAMLWNLHGASELQILEYADQTLHDPIPLPGMVAGELSISAGGTMLAMTVEGPSKPPTVELVDPRTREW ELVDREPSCGPVSDDPTLETIIARDGLTFSGWLFRPPEGVETIGAMLFLHGGPEGQGRPGYNEFFPALLD EGICVFLPNVRGSGGFGRAFMHADDRERRFAAIDDVADAARFLVGNGHAPAGRVACCGWSYGGYLTQAAL TFHPDEFAAGISICGMSDLNSWYRNTEQWIAAAAYPKYGHPVSDQDLLERLSPLPRADKVTAPLLLVHGL NDTNVPPGESQQMYDALTELGRRVELLTFEDDGHEIDKRENRAVLRKAMTAWLVEAFAD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4095 | - | - | 100% (620) | peptidase S9 prolyl oligopeptidase |
M. vanbaalenii PYR-1 | Mvan_5922 | - | 4e-30 | 31.29% (310) | peptidase S9 prolyl oligopeptidase |
M. vanbaalenii PYR-1 | Mvan_0785 | - | 4e-12 | 28.71% (202) | prolyl oligopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0466c | - | 1e-10 | 26.99% (226) | peptidase |
M. gilvum PYR-GCK | Mflv_2548 | - | 0.0 | 89.19% (620) | peptidase S9 prolyl oligopeptidase |
M. tuberculosis H37Rv | Rv0457c | - | 1e-10 | 26.99% (226) | peptidase |
M. leprae Br4923 | MLBr_02226 | ptrB | 2e-07 | 24.35% (230) | protease II |
M. abscessus ATCC 19977 | MAB_4725 | - | 2e-33 | 33.01% (312) | peptidase |
M. marinum M | MMAR_0779 | - | 4e-14 | 27.51% (229) | peptidase |
M. avium 104 | MAV_0727 | - | 6e-09 | 23.66% (262) | protease 2 |
M. smegmatis MC2 155 | MSMEG_4719 | - | 0.0 | 77.99% (618) | peptidase S9, prolyl oligopeptidase |
M. thermoresistible (build 8) | TH_4519 | - | 0.0 | 75.04% (621) | PUTATIVE peptidase S9, prolyl oligopeptidase active site domain |
M. ulcerans Agy99 | MUL_0498 | ptrB | 4e-10 | 26.52% (230) | protease II (oligopeptidase B), PtrB |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_4095|M.vanbaalenii_PYR-1 ----------------------------------------MAEQVRRIYG Mflv_2548|M.gilvum_PYR-GCK ----------------MRALSASATGPPVTTGADRAQSGTVAEQVRRIYG MSMEG_4719|M.smegmatis_MC2_155 ----------------------------------------------MNYG TH_4519|M.thermoresistible__bu ----------------------------------------VAEQVRATYG Mb0466c|M.bovis_AF2122/97 -----------MASMTFEP---APDGAD----PYLWLEDVTGAEALDWVR Rv0457c|M.tuberculosis_H37Rv --------------MTFEP---APDGAD----PYLWLEDVTGAEALDWVR MMAR_0779|M.marinum_M -----------MAPKAPEAPQ-APDAADTTTDPYLWLEDVTGEEALDWVR MAV_0727|M.avium_104 MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPDVIAHLE MUL_0498|M.ulcerans_Agy99 MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVEVIAHLE MLBr_02226|M.leprae_Br4923 MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLD MAB_4725|M.abscessus_ATCC_1997 ------------------------------MGLPKLITVEEFFEPPVRTS Mvan_4095|M.vanbaalenii_PYR-1 ASMSPDATAFAH-----------------LVDDGGYPRAVQR--FLRGWR Mflv_2548|M.gilvum_PYR-GCK ASMSPDATAFAH-----------------LVDDGGYPRAVQR--FLRGWR MSMEG_4719|M.smegmatis_MC2_155 ASLSPDATAFAH-----------------LVDDGGFPRAVQR--FLRGWR TH_4519|M.thermoresistible__bu ASLSPDATAFAH-----------------LVDDGGFPRAVQR--FLRGWR Mb0466c|M.bovis_AF2122/97 ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW Rv0457c|M.tuberculosis_H37Rv ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW MMAR_0779|M.marinum_M ARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYDFW MAV_0727|M.avium_104 AESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYYAR MUL_0498|M.ulcerans_Agy99 AENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYAR MLBr_02226|M.leprae_Br4923 AENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSR MAB_4725|M.abscessus_ATCC_1997 ASISPDGTMIAY----------------------LAPRKNRLNVWVQGIG * . . : : Mvan_4095|M.vanbaalenii_PYR-1 ASSSRDVELPVEGPVTR----------VMHSADGHWLACQVAPEGGSRSQ Mflv_2548|M.gilvum_PYR-GCK ASSSRDVELPVEGPVTR----------VLHSADGHWLACQVAPEGGTRSQ MSMEG_4719|M.smegmatis_MC2_155 ASSSRDVELPVVGPVLR----------VLHSADGHWLACEVAPEGATRSQ TH_4519|M.thermoresistible__bu ASSSRDVELPVVGPVRR----------VLHSPDGGWLACEVAPDGSDRSQ Mb0466c|M.bovis_AF2122/97 RDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRADDQ Rv0457c|M.tuberculosis_H37Rv RDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRADDQ MMAR_0779|M.marinum_M RDANNPRGLWRRTTLES----------YRTDAPEWDVLIDVDELGRTDNK MAV_0727|M.avium_104 TYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVE--AEGH MUL_0498|M.ulcerans_Agy99 TFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEE--AEGH MLBr_02226|M.leprae_Br4923 TFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAE--AEGH MAB_4725|M.abscessus_ATCC_1997 STEARCVTHDETRSVTG----------FFWVDDPRWLLYVQDSGGDENWH . . : : Mvan_4095|M.vanbaalenii_PYR-1 IWVVTTDPDDRDARRIDRWP-SGVEGTAELISWDGTLVAAILTG---EDG Mflv_2548|M.gilvum_PYR-GCK IWVVTTDPDDRAARRIDHWP-SGVDGTAELIGWDGTWVAAILTG---EDG MSMEG_4719|M.smegmatis_MC2_155 IWVVTTDPDDRDARRIDSWP-DGTEGTAELIGWDGTKVAAILTG---DDG TH_4519|M.thermoresistible__bu IWVVTTDPDDRGAHRIDSWPPDAPEGAAELIAWDGNRIAAILTG---QDG Mb0466c|M.bovis_AF2122/97 KWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPP Rv0457c|M.tuberculosis_H37Rv KWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPP MMAR_0779|M.marinum_M KWVWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFELPE MAV_0727|M.avium_104 EFFALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EIAD MUL_0498|M.ulcerans_Agy99 DFFALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EIAD MLBr_02226|M.leprae_Br4923 AFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EIVG MAB_4725|M.abscessus_ATCC_1997 LYRVDLSTPDATAVDLTPFPGARLLGLERPYGRSGKVYIQLNHR--RIDQ : . . Mvan_4095|M.vanbaalenii_PYR-1 VGTSCLLDPSGTTVIVLDRRSGGRLVDAWGG-ASLVRVGPRGYRDLIMLR Mflv_2548|M.gilvum_PYR-GCK VGSSCLIDPSGGTTTVLDRRSGGRLVDSWAG-ASLVRVGPRGYRDLIMLR MSMEG_4719|M.smegmatis_MC2_155 VGSSCLIDPGTGETTVLDRRSSGRLVDSWQG-ASLIRVGPRGYRELIMLW TH_4519|M.thermoresistible__bu VGSSCLIDPADGSTVVLDRRSGGRLVDAWAG-AALIRVGPRGYRELIMLH Mb0466c|M.bovis_AF2122/97 AKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFE Rv0457c|M.tuberculosis_H37Rv AKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFE MMAR_0779|M.marinum_M AKSQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMIFQ MAV_0727|M.avium_104 IAAGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAGSGEA-PELVYH MUL_0498|M.ulcerans_Agy99 IGAGATWAADHRTVYYITVD-----AAWRPDTVWRYRLGSPGS-SERVYH MLBr_02226|M.leprae_Br4923 IGAGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLGSGQP-SEQVYH MAB_4725|M.abscessus_ATCC_1997 IDLYELDIASGELTMLAENPGGVMAWFCGPNHEVFAQSLTPGGDIEFSRY : Mvan_4095|M.vanbaalenii_PYR-1 ALTETALLPYDPGSTTDTGIILDDHSP----RRLRSGPEGETTDLYYPVK Mflv_2548|M.gilvum_PYR-GCK GLTETGLLPYDPGSTTDTGVILDDHHP----RRLRTGPDGELSELYHPAK MSMEG_4719|M.smegmatis_MC2_155 GQREIALLPYDPGSTTDYGVILDDHSP----RRVRSGLDGETVTLMEPHK TH_4519|M.thermoresistible__bu GNTEMALLPSDPGSTTDFGVILDDHSA----RRLRRGPDGELTKLYQPAK Mb0466c|M.bovis_AF2122/97 GAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTD Rv0457c|M.tuberculosis_H37Rv GAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTD MMAR_0779|M.marinum_M GAHTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGTELIPLDVPTD MAV_0727|M.avium_104 EADEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLPRR MUL_0498|M.ulcerans_Agy99 EPDERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRR MLBr_02226|M.leprae_Br4923 EADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRR MAB_4725|M.abscessus_ATCC_1997 ESGALRPLCVYDGADYPVGMNPTQMTPDGSGMWLGSSRDTDRTRLVR--- : Mvan_4095|M.vanbaalenii_PYR-1 DYGLD--------STEGYVR-------ALIRSENGAQHARLLEVTVTADG Mflv_2548|M.gilvum_PYR-GCK IYGVN--------STEGYVR-------ALIRSENGAEHARLLEVTVSAEG MSMEG_4719|M.smegmatis_MC2_155 YFQADGESHTTEGTTEGYVR-------ALIRSENGASHARLLEVTVTADG TH_4519|M.thermoresistible__bu RYPRE--------STEGYVR-------ALIRSDNGAGYARLLEVTTTADG Mb0466c|M.bovis_AF2122/97 AS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSA Rv0457c|M.tuberculosis_H37Rv AS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSA MMAR_0779|M.marinum_M ASSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSGTS MAV_0727|M.avium_104 DG-VEYSVEHA---VVGGQD------RFLILHNDGAVNFTLTEAPVSDPT MUL_0498|M.ulcerans_Agy99 EG-VEYSVEHA---VIGGQD------RFLILHNDGAVNFTLVEAPVDDPT MLBr_02226|M.leprae_Br4923 DG-IEYSVEHAPSGLVGGQD------RFLILHNDGAVNFTLVESPVSNPE MAB_4725|M.abscessus_ATCC_1997 --------------------------LDLATGAESTIDSHPAYDLAAALG .: Mvan_4095|M.vanbaalenii_PYR-1 VSYQVVAERPGYELDEFTVSDDLSTVAMLWNLHGASELQILEYADQTLHD Mflv_2548|M.gilvum_PYR-GCK VTYQVVAERPGCELDEFTVSDDLSTVAILWNIHGASELQILEYADGTLYD MSMEG_4719|M.smegmatis_MC2_155 VSYHVVAERPGYELDEFVVSDDLSTVAMLWNVDGRSELQILEYADETLSE TH_4519|M.thermoresistible__bu VAYQVVAERPGHDLDEFVVSDDLSTVALLWNIDGASELQILQYADNTLSE Mb0466c|M.bovis_AF2122/97 ELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRRE Rv0457c|M.tuberculosis_H37Rv ELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRRE MMAR_0779|M.marinum_M DLHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWRRE MAV_0727|M.avium_104 RQRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYARP MUL_0498|M.ulcerans_Agy99 RQRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYGEV MLBr_02226|M.leprae_Br4923 QQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEP MAB_4725|M.abscessus_ATCC_1997 LPPTLIRHRKSGELLAARYLGARQEIRVLDPDFG-----------PVLEK :. * : Mvan_4095|M.vanbaalenii_PYR-1 PIPLPGMVAGELSISAGG----TMLAMTVEGPSKPPTVELVDPRTREWEL Mflv_2548|M.gilvum_PYR-GCK PIPLPGMVAGELSISAGG----SMLALTVEGPSKPPTVELVDPRTREWEL MSMEG_4719|M.smegmatis_MC2_155 PIPLPGMVASQLSISAGG----SMVAMTVQGPSLPPTVELVDPRTREWER TH_4519|M.thermoresistible__bu PIPLPGMVAGELSISAGG----SMVAMTVESPWLPPTVELVDPRTRQWEL Mb0466c|M.bovis_AF2122/97 PLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRL Rv0457c|M.tuberculosis_H37Rv PLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRL MMAR_0779|M.marinum_M PIAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATTQL MAV_0727|M.avium_104 EEISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGERTL MUL_0498|M.ulcerans_Agy99 EDVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGERTL MLBr_02226|M.leprae_Br4923 EEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTL MAB_4725|M.abscessus_ATCC_1997 LQELSDGDLAEVSSDEDG----RRWVVSFTHDRDPGVTYFYDHATGESHQ . : * Mvan_4095|M.vanbaalenii_PYR-1 VDREPSCGPVSDD---PTLETIIARDGLTFSGWLFRPPEGV-ETIGAMLF Mflv_2548|M.gilvum_PYR-GCK VDREPSSGPVSAD---PTLETVTARDGLTFTGWLFRPREGV-ETIGAMLF MSMEG_4719|M.smegmatis_MC2_155 IDREPSGGPVTGT---PTLEMITARDGLELNSWLYWPHT---EPIGAMLF TH_4519|M.thermoresistible__bu IDREPSTGPVTGT---PTLERLTARDGLELTGWLYRPPTGV-QPVGAMIF Mb0466c|M.bovis_AF2122/97 AEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDAD-NPGPTLLN Rv0457c|M.tuberculosis_H37Rv AEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDAD-NPGPTLLN MMAR_0779|M.marinum_M EQIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSD-GPGPTLLY MAV_0727|M.avium_104 LREQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIE-FPAPALIY MUL_0498|M.ulcerans_Agy99 LREQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQ-LPAPAMIY MLBr_02226|M.leprae_Br4923 LREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIR-FPAPAVLY MAB_4725|M.abscessus_ATCC_1997 LFR-PYPHLDPADLAPVVPVTITARDGLTLNSYLTLPVGTEPEGLPLVLV . : ** . : :: Mvan_4095|M.vanbaalenii_PYR-1 LHGGPEGQGRPGYN-EFFPALLDEGICVFLPNVRGSGGFGRAFMHADDRE Mflv_2548|M.gilvum_PYR-GCK LHGGPEGQGRPGYN-EFFPALLDEGICVFLPNVRGSGGFGRSFMHADDRE MSMEG_4719|M.smegmatis_MC2_155 LHGGPEGQARPEYN-EFYPQLLEAGIAVLTPNVRGSGGFGRAFMHADDKE TH_4519|M.thermoresistible__bu LHGGPEGQSRPGYN-EYFPPLLDRGITVFTPNVRGSGGFGRSFVHADDKE Mb0466c|M.bovis_AF2122/97 GYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMRE Rv0457c|M.tuberculosis_H37Rv GYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMRE MMAR_0779|M.marinum_M GYGGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMRE MAV_0727|M.avium_104 GYGAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKLL MUL_0498|M.ulcerans_Agy99 AYGAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLL MLBr_02226|M.leprae_Br4923 GYGAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLL MAB_4725|M.abscessus_ATCC_1997 VHGGPWHRDSWGFD-PTVQLLANRGYAVLQVNFRGSTGYGKAFTKAAIGE :*. :. * :.**. * : Mvan_4095|M.vanbaalenii_PYR-1 RRFAAIDDVADAARFLVGNGHAPAGRVACCGWSYGGYLTQAALTFHPDEF Mflv_2548|M.gilvum_PYR-GCK RRFAAIDDVADCVRFLVGNGHAPAGKVACCGWSYGGYLTQAALAFHPDEF MSMEG_4719|M.smegmatis_MC2_155 RRFAAIDDVADCVQYLVDKGLAPADKIACTGWSYGGYLTLAALTFHPELF TH_4519|M.thermoresistible__bu NRFRAIDDVADCVHYLVRNGLAPADRIACAGWSYGGYLTQAALAFHPDLF Mb0466c|M.bovis_AF2122/97 GRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKF Rv0457c|M.tuberculosis_H37Rv GRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKF MMAR_0779|M.marinum_M GRHKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEKF MAV_0727|M.avium_104 EKKNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPELF MUL_0498|M.ulcerans_Agy99 QKKNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPELF MLBr_02226|M.leprae_Br4923 EKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLF MAB_4725|M.abscessus_ATCC_1997 FAGKMHDDLIDAVDWAVEQGYADPGRIAIFGGSYGGYSALVGVTFTPDVF *. . * . : .: * * ** *: * Mvan_4095|M.vanbaalenii_PYR-1 AAGISICGMSDLNSWYRNTEQWIAAAAYPKYGHPVSD----QDLLERLSP Mflv_2548|M.gilvum_PYR-GCK AAGISICGMSDLNSWYRSTEQWIAAAAYPKYGHPVSD----QSLLEQLSP MSMEG_4719|M.smegmatis_MC2_155 AAGISICGMSDLNTFYRNTEPWIAAAAYPKYGHPVAD----RDLLEKLSP TH_4519|M.thermoresistible__bu AAGISVCGMSDLTTWYQTTEPWIAQSSYTEYGHPVAD----RDLLERLSP Mb0466c|M.bovis_AF2122/97 GALVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD-----WKFISEYSP Rv0457c|M.tuberculosis_H37Rv GALVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD-----WKFISEYSP MMAR_0779|M.marinum_M GALVCNVPLLDMKRYHLLLAGASWVAEYGDPDNPDD-----WAFISEYSP MAV_0727|M.avium_104 AGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLADKDV-YFYMKSYSP MUL_0498|M.ulcerans_Agy99 AGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEV-YAYMKSYSP MLBr_02226|M.leprae_Br4923 TGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDF-YSYIKSYSP MAB_4725|M.abscessus_ATCC_1997 AAAVDYVGISNLANFMRTLPPFVRPNLANNWYRYVGDPAVPEQEADMLAR . : : : . . . : Mvan_4095|M.vanbaalenii_PYR-1 LP--RADKVTAPLLLVHGLNDTNVPPGESQQMYDALTEL---GRRVELLT Mflv_2548|M.gilvum_PYR-GCK LP--RADAISAPLLLVHGLNDTNVPPGESEQMWEALTAL---GREVELLT MSMEG_4719|M.smegmatis_MC2_155 LP--RAHALTAPLLLVHGANDTNVPPSESLQMYDALHDL---GRPVELLM TH_4519|M.thermoresistible__bu LT--HAAAVTAPLLLVHGASDTNVPPSESIQMHTALERL---GRPVKLLM Mb0466c|M.bovis_AF2122/97 YQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYE Rv0457c|M.tuberculosis_H37Rv YQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYE MMAR_0779|M.marinum_M YQNISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVWYYE MAV_0727|M.avium_104 YENVDA-RRYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFLLKT MUL_0498|M.ulcerans_Agy99 YENVAD-RRYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVLLKT MLBr_02226|M.leprae_Br4923 YENVEA-KQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKT MAB_4725|M.abscessus_ATCC_1997 SPISRVDRIRTPLLVAQGANDVRVVQAESDNIVAALRAR---GVEVEYMV ..:: . * .* .. : ** * . Mvan_4095|M.vanbaalenii_PYR-1 FEDDGHEIDKRENRAVLRKAMTAWLVEAFAD------------------- Mflv_2548|M.gilvum_PYR-GCK FEDDGHEIDKRENRAVLRKTMCEWLTAAFAE------------------- MSMEG_4719|M.smegmatis_MC2_155 FADDGHEIIKRENRAVLVDAMERWLVKAFTA------------------- TH_4519|M.thermoresistible__bu FDDDGHEIVRRENRATLVEAMSHWLMSAFAERRREAS------------- Mb0466c|M.bovis_AF2122/97 NIEGGHAGAADNAQIAFKSALSFAFLWRMLAG------------------ Rv0457c|M.tuberculosis_H37Rv NIEGGHAGAADNAQIAFKSALSFAFLWRMLAG------------------ MMAR_0779|M.marinum_M NIEGGHGGAADNEQLAFKSALSYSFLWRMLGSRK---------------- MAV_0727|M.avium_104 QMNAGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPDPQG MUL_0498|M.ulcerans_Agy99 QMNAGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG------------ MLBr_02226|M.leprae_Br4923 QMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG MAB_4725|M.abscessus_ATCC_1997 KADEGHGFLNPENQIDLHRATERFLAQHVGGRQVS--------------- ** . . :