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TFEPAPDGADPYLWLEDVTGAEALDWVRARNKPTTAAFCDAEFERMRVEALEVLDTDARIPYVNRRGNYL YNFWRDAANPRGLWRRTTLDSYRTDSPGWDVLIDVDELGRADDQKWVWGGAGVIEPDYTRALIGLSPGGS DASIVREFDMLTREFVEDGFQLPPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAE TIFEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTDASVSIHRDWLLIELRT DWTVATTRYTAGSLLAAEYDEFLAGSAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATPGS WRREPLSGIPAATNTVIVSADSHGDEFFLDSSGFDTPSRLMRGTDDGRLAEIKSAPAFFDAENMAVTQYF ATSDDGTSIPYFVVRRTDADNPGPTLLNGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPG WHTQAMREGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGALVCDVPLLDM KRYHLLLAGASWMAEYGDPDNPDDWKFISEYSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQ AAGHPVWYYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0457c | - | - | 100% (673) | PROBABLE PEPTIDASE |
M. tuberculosis H37Rv | Rv0782 | ptrBb | 2e-35 | 34.16% (281) | oligopeptidase B |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0466c | - | 0.0 | 100.00% (673) | peptidase |
M. gilvum PYR-GCK | Mflv_0127 | - | 0.0 | 73.20% (668) | prolyl oligopeptidase |
M. leprae Br4923 | MLBr_02226 | ptrB | 3e-34 | 35.23% (264) | protease II |
M. abscessus ATCC 19977 | MAB_4130 | - | 0.0 | 67.72% (666) | peptidase |
M. marinum M | MMAR_0779 | - | 0.0 | 76.90% (684) | peptidase |
M. avium 104 | MAV_0727 | - | 6e-33 | 33.98% (256) | protease 2 |
M. smegmatis MC2 155 | MSMEG_0899 | - | 0.0 | 66.06% (663) | prolyl oligopeptidase family protein |
M. thermoresistible (build 8) | TH_3439 | - | 0.0 | 71.36% (660) | PUTATIVE Prolyl oligopeptidase |
M. ulcerans Agy99 | MUL_0498 | ptrB | 8e-34 | 25.11% (713) | protease II (oligopeptidase B), PtrB |
M. vanbaalenii PYR-1 | Mvan_0785 | - | 0.0 | 73.76% (663) | prolyl oligopeptidase |
CLUSTAL 2.0.9 multiple sequence alignment Rv0457c|M.tuberculosis_H37Rv ---------------MTFEP--APDGAD----PYLWLEDVTGAEALDWVR Mb0466c|M.bovis_AF2122/97 ------------MASMTFEP--APDGAD----PYLWLEDVTGAEALDWVR MMAR_0779|M.marinum_M ------------MAPKAPEAPQAPDAADTTTDPYLWLEDVTGEEALDWVR Mflv_0127|M.gilvum_PYR-GCK -------------MGEVTDTRPEPTAHAPETDPYLWLEDVTGDDALAWVR Mvan_0785|M.vanbaalenii_PYR-1 -------------MVGVTDTDSK------QTDPYLWLEEVTGDDALAWVR MAB_4130|M.abscessus_ATCC_1997 -------------MTSARRS----------LDPYLWLEDIGGDEPLNWVR TH_3439|M.thermoresistible__bu -------------VDDERAREQHLD-----SDPYLWLEDITGDDALEWVR MSMEG_0899|M.smegmatis_MC2_155 -------------MWVADDD------------PHLWLEDITGDDALEWVR MAV_0727|M.avium_104 MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPDVIAHLE MUL_0498|M.ulcerans_Agy99 MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVEVIAHLE MLBr_02226|M.leprae_Br4923 MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLD *: **.: . : : : Rv0457c|M.tuberculosis_H37Rv ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW Mb0466c|M.bovis_AF2122/97 ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW MMAR_0779|M.marinum_M ARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYDFW Mflv_0127|M.gilvum_PYR-GCK AHNEPTVTELG----GERFEQMRAEALEVLDTDARIPYVRRRGEYLYNFW Mvan_0785|M.vanbaalenii_PYR-1 KHNDPTVADLG----GERFEQMRADALEVLDTDARIPYVRRRGAHLYNFW MAB_4130|M.abscessus_ATCC_1997 EHNAITTSEFS----GARFEEMRDEALAILNTDAQIPYVRRRGEYLYNFW TH_3439|M.thermoresistible__bu RHNEPTLAEFG----GDRFEQMRAEALEVLDTDARIPYVRRRGEYLYNFW MSMEG_0899|M.smegmatis_MC2_155 AHNDPTLEALG----GERFETIRGELLEVLDTDARIPYVRRRGEYLYNFW MAV_0727|M.avium_104 AESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYYAR MUL_0498|M.ulcerans_Agy99 AENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYAR MLBr_02226|M.leprae_Br4923 AENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSR .. . :. : : .: :. *:. * Rv0457c|M.tuberculosis_H37Rv RDAANPRGLWRRTTLDSYRTDSPG--------WDVLIDVDELGRADDQKW Mb0466c|M.bovis_AF2122/97 RDAANPRGLWRRTTLDSYRTDSPG--------WDVLIDVDELGRADDQKW MMAR_0779|M.marinum_M RDANNPRGLWRRTTLESYRTDAPE--------WDVLIDVDELGRTDNKKW Mflv_0127|M.gilvum_PYR-GCK RDAANPKGLWRRTTLESYRAENTD--------WDVIIDVDELARTDGENW Mvan_0785|M.vanbaalenii_PYR-1 RDATNPKGLWRRTTLESYLTEKPA--------WDVIIDVDELARADGQNW MAB_4130|M.abscessus_ATCC_1997 RDATNSRGLWRRTTLDRYRRHDPE--------WDVVIDVDALAATEDENW TH_3439|M.thermoresistible__bu RDADNPRGLWRRTTLDSYRQESPD--------WEVLIDVDELARADDENW MSMEG_0899|M.smegmatis_MC2_155 RDEANPKGVWRRTTLESYRTDEPE--------WDVIIDVDELAREDGENW MAV_0727|M.avium_104 TYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVEAEGHEF MUL_0498|M.ulcerans_Agy99 TFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEEAEGHDF MLBr_02226|M.leprae_Br4923 TFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAF . : * . . : :* :.. : Rv0457c|M.tuberculosis_H37Rv VWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPPAK Mb0466c|M.bovis_AF2122/97 VWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPPAK MMAR_0779|M.marinum_M VWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFELPEAK Mflv_0127|M.gilvum_PYR-GCK VWAGADVLEPTHSVALISLSRGGADAAVVREFDMRTRTFVDGGFELAEAK Mvan_0785|M.vanbaalenii_PYR-1 VWAGADVIEPDHSLALISLSRGGSDAAVVREFDMRTREFVTGGFELSEAK MAB_4130|M.abscessus_ATCC_1997 VWAGAAVLRPDFQRALVSLSRGGSDAVVVREFDLETRQFVAGGFELPEAK TH_3439|M.thermoresistible__bu VWAGATVIEPDFSLALIELSRGGADATVVREFDMVTKQFVKDGFELPEAK MSMEG_0899|M.smegmatis_MC2_155 VWSGAEVIEPEYTLALISLSRGGADAVVTREFDMRTRAFVTDGFHLPEAK MAV_0727|M.avium_104 FALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EIADIA MUL_0498|M.ulcerans_Agy99 FALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EIADIG MLBr_02226|M.leprae_Br4923 FALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EIVGIG . *: : :. * : * *: * . .: Rv0457c|M.tuberculosis_H37Rv SQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFEGA Mb0466c|M.bovis_AF2122/97 SQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFEGA MMAR_0779|M.marinum_M SQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMIFQGA Mflv_0127|M.gilvum_PYR-GCK SQVSWEDENTLLIGTDFGAGSLTESGYPRLVKRWRRGQALTDAETLFSGA Mvan_0785|M.vanbaalenii_PYR-1 SQVSWEDADTLLVGTDFGEGSLTESGYPRLVKRWRRGQPLAEAETVFSGS MAB_4130|M.abscessus_ATCC_1997 TQISWVDADTVYVGTDFGPGSLTDSGYPRLVKRWKRGQSLDDAELVFSGE TH_3439|M.thermoresistible__bu TTIAWQDRDTVLVGTDFGPGSLTESGYPRIAKRWRRGRPLEEAETIFEGE MSMEG_0899|M.smegmatis_MC2_155 SSTSWEDENTLLVCTDFGPGSMTESGYPRVAKRWRRGEPLENAETVYEAE MAV_0727|M.avium_104 AGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAG-SGEAPELVYHEA MUL_0498|M.ulcerans_Agy99 AGATWAADHRTVYYITVD-----AAWRPDTVWRYRLG-SPGSSERVYHEP MLBr_02226|M.leprae_Br4923 AGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLG-SGQPSEQVYHEA : * . .. : * * : * . .* :: Rv0457c|M.tuberculosis_H37Rv GTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGS-ELIRIEAPTDA Mb0466c|M.bovis_AF2122/97 GTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGS-ELIRIEAPTDA MMAR_0779|M.marinum_M HTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGT-ELIPLDVPTDA Mflv_0127|M.gilvum_PYR-GCK ESDVLVAGSRDHTPGFERTLIARAFDFFNEQVYELRGG-ELIRIDTPTDA Mvan_0785|M.vanbaalenii_PYR-1 ESDVVVAGSRDRTDGFERTLVSRALDFFNEQVYELRDG-ELIRIDTPTDA MAB_4130|M.abscessus_ATCC_1997 ASDVTVGASFDDTPGFERTLISRATDFFNSEVHELTADGELLRIDVPTDA TH_3439|M.thermoresistible__bu VTDVSVSAGYDATPGYERLVVGRSIDFFNRRRFELRDG-ELIEIKVPTDA MSMEG_0899|M.smegmatis_MC2_155 PTDIRVIAGVDRTPGYEHTRLGRYTDFYNRVRYEVRDG-ELVLIDVPTDS MAV_0727|M.avium_104 DEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLPRRDG MUL_0498|M.ulcerans_Agy99 DERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRREG MLBr_02226|M.leprae_Br4923 DERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDG . . : : . :: : :. Rv0457c|M.tuberculosis_H37Rv S-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSAE Mb0466c|M.bovis_AF2122/97 S-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSAE MMAR_0779|M.marinum_M SSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSGTSD Mflv_0127|M.gilvum_PYR-GCK S-ISLHREWLLIELRTEWQ------HLGHTYPAGSLLAADYEEFLAGAAE Mvan_0785|M.vanbaalenii_PYR-1 S-ISIHRQWLLIELRTDWS------YRFQNYPAGSLLAADYEEFLDGRGE MAB_4130|M.abscessus_ATCC_1997 S-ASIHREWLLIELKSSWQ------VGDIEYSAGTLLAARYRDYVAGDRT TH_3439|M.thermoresistible__bu G-VSVHRDWLLIRLRSEWT------VGSTTYPAGCLLAARYDDYLAGTAD MSMEG_0899|M.smegmatis_MC2_155 T-LSLHQEWMLIALRTEWQ------VGEVTYPAGSLLATTFDEYLSGARD MAV_0727|M.avium_104 VEYSVEHA---VVGGQDRF--------LILHNDGAVNFTLTEAPVSDPTR MUL_0498|M.ulcerans_Agy99 VEYSVEHA---VIGGQDRF--------LILHNDGAVNFTLVEAPVDDPTR MLBr_02226|M.leprae_Br4923 IEYSVEHAPSGLVGGQDRF--------LILHNDGAVNFTLVESPVSNPEQ *:.: : . : * : : : . Rv0457c|M.tuberculosis_H37Rv LQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRREP Mb0466c|M.bovis_AF2122/97 LQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRREP MMAR_0779|M.marinum_M LHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWRREP Mflv_0127|M.gilvum_PYR-GCK LQVVFTPDAHTCLHHYAWTRDRLVVVTLADVASRVEVYTP---GEWTSEP Mvan_0785|M.vanbaalenii_PYR-1 VQVVFTPDAHTCLHHYAWTRDRLVVVTLADVASRVQVYTP---GTWTAEP MAB_4130|M.abscessus_ATCC_1997 LTPVFVPDEHASLHHYAWTRDRLTVAILRDVASEILVFTP---GSWRSEP TH_3439|M.thermoresistible__bu LAVVFEPDPHTSLETFAWTRDRLVMISLVDVVSRVEVVTP---GSWERTQ MSMEG_0899|M.smegmatis_MC2_155 LTIVYEPDPHSCLSSFSWTKDKLILVTLRDVVSHIEIVTP---GTWERRD MAV_0727|M.avium_104 QRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYARPE MUL_0498|M.ulcerans_Agy99 QRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYGEVE MLBr_02226|M.leprae_Br4923 QRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPE : . * * : . ..: : * : Rv0457c|M.tuberculosis_H37Rv LSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRLA Mb0466c|M.bovis_AF2122/97 LSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRLA MMAR_0779|M.marinum_M IAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATTQLE Mflv_0127|M.gilvum_PYR-GCK VHGLPENTNTVIVAADD--LGDEIFLDSSGFDTPSRLLYGTG---GGELA Mvan_0785|M.vanbaalenii_PYR-1 VADLPQNTNTTIAAADP--LGDEIFLDSSGFDTPSRLLHGTA---GGPLS MAB_4130|M.abscessus_ATCC_1997 LPGVPDNATTQIVAIDD--LGDEIFLDTSGFTQPSTLLRGEVGPAGASVS TH_3439|M.thermoresistible__bu VAGIPPNTNTMLVDADE--FGDEIFLDSSGFDTPSRLLWGRA---GGEIT MSMEG_0899|M.smegmatis_MC2_155 APDIPPVASTVVVDADH--LGDEVFYDSSGFTSPSRLLYGTA---GGPLV MAV_0727|M.avium_104 EISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGERTLL MUL_0498|M.ulcerans_Agy99 DVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGERTLL MLBr_02226|M.leprae_Br4923 EISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTLL . : .. :..: * : : Rv0457c|M.tuberculosis_H37Rv EIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLLNGY Mb0466c|M.bovis_AF2122/97 EIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLLNGY MMAR_0779|M.marinum_M QIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSDGPGPTLLYGY Mflv_0127|M.gilvum_PYR-GCK EIKRAPSFFDAADLEVSQFFATSDDGTEIPYFVVGHRHRQGPGPTLLGGY Mvan_0785|M.vanbaalenii_PYR-1 EIKQAPSFFDSADLEVSQYFATSDDGTRVPYFVVGHRHRQGPGPTLLGGY MAB_4130|M.abscessus_ATCC_1997 PIKTAPSFFDDAAFEVAQHFARSDDGTSIPYFVVRAKGSEAAGPTLLGGY TH_3439|M.thermoresistible__bu EIKRAPSFFDTADLAVSQHFAISDDGTRIPYFVVGQRHKKIPGPTLLSGY MSMEG_0899|M.smegmatis_MC2_155 QLKSAPAFFDADGIEVEQFFATSDDGTQVPYFVVGRRSE--PAPTYLYGY MAV_0727|M.avium_104 REQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIEFPAPALIYGY MUL_0498|M.ulcerans_Agy99 REQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMIYAY MLBr_02226|M.leprae_Br4923 REQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGY : . : : :* ::*** :* :* ..*: : .* Rv0457c|M.tuberculosis_H37Rv GGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMREGR Mb0466c|M.bovis_AF2122/97 GGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMREGR MMAR_0779|M.marinum_M GGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMREGR Mflv_0127|M.gilvum_PYR-GCK GGFEVSRTPGYDGVMGRLWLSRGGTYVLANIRGGGEYGPTWHTQAMREGR Mvan_0785|M.vanbaalenii_PYR-1 GGFEVARTPGYDGVLGRLWLARGGTYVLANIRGGGEYGPTWHTQAMREGR MAB_4130|M.abscessus_ATCC_1997 GGFEVARTPGYDGVLGRLWLSRGGTYVLANIRGGGEYGPVWHTQAMREGR TH_3439|M.thermoresistible__bu GGFEVSNTPSYSGVLGRLWLSRGGTYVLANIRGGGEYGPTWHTQAMRENR MSMEG_0899|M.smegmatis_MC2_155 GGFQSAQTPGYGGGIGRAWLSRGGTFVQANIRGGGEYGPQWHTQAMRENR MAV_0727|M.avium_104 GAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKLLEK MUL_0498|M.ulcerans_Agy99 GAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLLQK MLBr_02226|M.leprae_Br4923 GAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEK *.:: . * :. * ** :. *::***** * *: :. : Rv0457c|M.tuberculosis_H37Rv DKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGA Mb0466c|M.bovis_AF2122/97 DKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGA MMAR_0779|M.marinum_M HKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEKFGA Mflv_0127|M.gilvum_PYR-GCK HLVYEDFAAVAKDLVARGITTVEQLGAQGGSNGGLLMGVMLTRYPDLFGA Mvan_0785|M.vanbaalenii_PYR-1 HLVAEDFASVARDLAARGITTVEQLGAQGGSNGGLLMGIMLTKYPELFGA MAB_4130|M.abscessus_ATCC_1997 HLVYEDFAAVARDLVARGITTAAQLGAQGGSNGGLLMGVMLTAYPELFGA TH_3439|M.thermoresistible__bu HLVYEDFAAVARDLVERGVTTVEQLGAQGGSNGGLLMGVMLTRYPELFGA MSMEG_0899|M.smegmatis_MC2_155 HLVYEDFAAIAADLVRRGITTVDQLGASGGSNGGLLMGVMLTQYPELFGA MAV_0727|M.avium_104 KNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPELFAG MUL_0498|M.ulcerans_Agy99 KNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPELFAG MLBr_02226|M.leprae_Br4923 KNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTG . . ** : * .*. . * .* * *** ****:* : . *: * . Rv0457c|M.tuberculosis_H37Rv LVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISEYSPYQN Mb0466c|M.bovis_AF2122/97 LVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISEYSPYQN MMAR_0779|M.marinum_M LVCNVPLLDMKRYHLLLAGASWVAEYGDPDNPDD----WAFISEYSPYQN Mflv_0127|M.gilvum_PYR-GCK LVCSVPLLDMKRFHLLLAGASWMAEYGNPDDPDD----WAFISEYSPYQN Mvan_0785|M.vanbaalenii_PYR-1 LVCSVPLLDMKRFHLLLAGASWVAEYGDPDNPDD----WAFISEYSPYQN MAB_4130|M.abscessus_ATCC_1997 LVCQVPLLDMRRYHLLLAGASWVAEYGDPDNPED----WEFISKYSPYQN TH_3439|M.thermoresistible__bu LVCSVPLLDMRRFHLLLAGASWVAEYGDPDNPDD----WEFISEYSPYHN MSMEG_0899|M.smegmatis_MC2_155 LVCSVPLLDMKRFHLLLAGASWVAEYGNPDDPAD----WEFISKYSPYQN MAV_0727|M.avium_104 ILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLADKDVYFYMKSYSPYEN MUL_0498|M.ulcerans_Agy99 ILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEVYAYMKSYSPYEN MLBr_02226|M.leprae_Br4923 ILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYEN ::..**::* * : . ::*:.: .:* : ::..****.* Rv0457c|M.tuberculosis_H37Rv ISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYENIE Mb0466c|M.bovis_AF2122/97 ISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYENIE MMAR_0779|M.marinum_M ISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVWYYENIE Mflv_0127|M.gilvum_PYR-GCK ISADRRYPPVLITTSTRDDRVHPGHARKMTAALEAA---GHPVSYYENIE Mvan_0785|M.vanbaalenii_PYR-1 ISADRRYPPVLITTSTRDDRVHPGHARKMTAALEAA---GHPVRYYENIE MAB_4130|M.abscessus_ATCC_1997 ISMDRRYPPVLVTTSTRDDRVHPGHARKMTAALQEA---GQPVWYYENIE TH_3439|M.thermoresistible__bu ISTDRSYPPILITTSTRDDRVHPGHARKMTAALEEA---GHRVHYYENIE MSMEG_0899|M.smegmatis_MC2_155 ISADGKYPPILITTSTRDDRVHPGHARKMTAALEAA---GHRVYYYENIE MAV_0727|M.avium_104 VDAR-RYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFLLKTQMN MUL_0498|M.ulcerans_Agy99 VADR-RYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVLLKTQMN MLBr_02226|M.leprae_Br4923 VEAK-QYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMA : **.:: ** .* **: .. * ***. : * . :: Rv0457c|M.tuberculosis_H37Rv GGHAGAADNAQIAFKSALSFAFLWRMLAG------------------ Mb0466c|M.bovis_AF2122/97 GGHAGAADNAQIAFKSALSFAFLWRMLAG------------------ MMAR_0779|M.marinum_M GGHGGAADNEQLAFKSALSYSFLWRMLGSRK---------------- Mflv_0127|M.gilvum_PYR-GCK GGHAGASDNPQVAFRSALVYEYLLRTLGG------------------ Mvan_0785|M.vanbaalenii_PYR-1 GGHAGASDNPQIAFRSALIYEFLHRTLNGN----------------- MAB_4130|M.abscessus_ATCC_1997 GGHGGAANNEQSAFKAALAIEFLWRQLAP------------------ TH_3439|M.thermoresistible__bu GGHAGAADNAQTAFRAALIYEFLHRTVGAAPADG------------- MSMEG_0899|M.smegmatis_MC2_155 GGHGGAADNKQAAFKGALTYEFLWRMLTGGNLD-------------- MAV_0727|M.avium_104 AGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPDPQG MUL_0498|M.ulcerans_Agy99 AGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG------------ MLBr_02226|M.leprae_Br4923 AGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG .**.* :.. : . * :*