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M. tuberculosis H37Rv Rv0457c (-)

annotation: PROBABLE PEPTIDASE
coordinates: 547586 - 549607
length: 673

TFEPAPDGADPYLWLEDVTGAEALDWVRARNKPTTAAFCDAEFERMRVEALEVLDTDARIPYVNRRGNYL
YNFWRDAANPRGLWRRTTLDSYRTDSPGWDVLIDVDELGRADDQKWVWGGAGVIEPDYTRALIGLSPGGS
DASIVREFDMLTREFVEDGFQLPPAKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAE
TIFEGAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTDASVSIHRDWLLIELRT
DWTVATTRYTAGSLLAAEYDEFLAGSAELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATPGS
WRREPLSGIPAATNTVIVSADSHGDEFFLDSSGFDTPSRLMRGTDDGRLAEIKSAPAFFDAENMAVTQYF
ATSDDGTSIPYFVVRRTDADNPGPTLLNGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPG
WHTQAMREGRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGALVCDVPLLDM
KRYHLLLAGASWMAEYGDPDNPDDWKFISEYSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQ
AAGHPVWYYENIEGGHAGAADNAQIAFKSALSFAFLWRMLAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0457c--100% (673)PROBABLE PEPTIDASE
M. tuberculosis H37RvRv0782ptrBb2e-3534.16% (281) oligopeptidase B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0466c-0.0100.00% (673) peptidase
M. gilvum PYR-GCKMflv_0127-0.073.20% (668) prolyl oligopeptidase
M. leprae Br4923MLBr_02226ptrB3e-3435.23% (264) protease II
M. abscessus ATCC 19977MAB_4130-0.067.72% (666) peptidase
M. marinum MMMAR_0779-0.076.90% (684) peptidase
M. avium 104MAV_0727-6e-3333.98% (256) protease 2
M. smegmatis MC2 155MSMEG_0899-0.066.06% (663) prolyl oligopeptidase family protein
M. thermoresistible (build 8)TH_3439-0.071.36% (660) PUTATIVE Prolyl oligopeptidase
M. ulcerans Agy99MUL_0498ptrB8e-3425.11% (713) protease II (oligopeptidase B), PtrB
M. vanbaalenii PYR-1Mvan_0785-0.073.76% (663) prolyl oligopeptidase

CLUSTAL 2.0.9 multiple sequence alignment


Rv0457c|M.tuberculosis_H37Rv        ---------------MTFEP--APDGAD----PYLWLEDVTGAEALDWVR
Mb0466c|M.bovis_AF2122/97           ------------MASMTFEP--APDGAD----PYLWLEDVTGAEALDWVR
MMAR_0779|M.marinum_M               ------------MAPKAPEAPQAPDAADTTTDPYLWLEDVTGEEALDWVR
Mflv_0127|M.gilvum_PYR-GCK          -------------MGEVTDTRPEPTAHAPETDPYLWLEDVTGDDALAWVR
Mvan_0785|M.vanbaalenii_PYR-1       -------------MVGVTDTDSK------QTDPYLWLEEVTGDDALAWVR
MAB_4130|M.abscessus_ATCC_1997      -------------MTSARRS----------LDPYLWLEDIGGDEPLNWVR
TH_3439|M.thermoresistible__bu      -------------VDDERAREQHLD-----SDPYLWLEDITGDDALEWVR
MSMEG_0899|M.smegmatis_MC2_155      -------------MWVADDD------------PHLWLEDITGDDALEWVR
MAV_0727|M.avium_104                MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPDVIAHLE
MUL_0498|M.ulcerans_Agy99           MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVEVIAHLE
MLBr_02226|M.leprae_Br4923          MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLD
                                                                    *: **.:  . : :  : 

Rv0457c|M.tuberculosis_H37Rv        ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW
Mb0466c|M.bovis_AF2122/97           ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW
MMAR_0779|M.marinum_M               ARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYDFW
Mflv_0127|M.gilvum_PYR-GCK          AHNEPTVTELG----GERFEQMRAEALEVLDTDARIPYVRRRGEYLYNFW
Mvan_0785|M.vanbaalenii_PYR-1       KHNDPTVADLG----GERFEQMRADALEVLDTDARIPYVRRRGAHLYNFW
MAB_4130|M.abscessus_ATCC_1997      EHNAITTSEFS----GARFEEMRDEALAILNTDAQIPYVRRRGEYLYNFW
TH_3439|M.thermoresistible__bu      RHNEPTLAEFG----GDRFEQMRAEALEVLDTDARIPYVRRRGEYLYNFW
MSMEG_0899|M.smegmatis_MC2_155      AHNDPTLEALG----GERFETIRGELLEVLDTDARIPYVRRRGEYLYNFW
MAV_0727|M.avium_104                AESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYYAR
MUL_0498|M.ulcerans_Agy99           AENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYAR
MLBr_02226|M.leprae_Br4923          AENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSR
                                     ..  .            :.    : :    .:  :.   *:.   *   

Rv0457c|M.tuberculosis_H37Rv        RDAANPRGLWRRTTLDSYRTDSPG--------WDVLIDVDELGRADDQKW
Mb0466c|M.bovis_AF2122/97           RDAANPRGLWRRTTLDSYRTDSPG--------WDVLIDVDELGRADDQKW
MMAR_0779|M.marinum_M               RDANNPRGLWRRTTLESYRTDAPE--------WDVLIDVDELGRTDNKKW
Mflv_0127|M.gilvum_PYR-GCK          RDAANPKGLWRRTTLESYRAENTD--------WDVIIDVDELARTDGENW
Mvan_0785|M.vanbaalenii_PYR-1       RDATNPKGLWRRTTLESYLTEKPA--------WDVIIDVDELARADGQNW
MAB_4130|M.abscessus_ATCC_1997      RDATNSRGLWRRTTLDRYRRHDPE--------WDVVIDVDALAATEDENW
TH_3439|M.thermoresistible__bu      RDADNPRGLWRRTTLDSYRQESPD--------WEVLIDVDELARADDENW
MSMEG_0899|M.smegmatis_MC2_155      RDEANPKGVWRRTTLESYRTDEPE--------WDVIIDVDELAREDGENW
MAV_0727|M.avium_104                TYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVEAEGHEF
MUL_0498|M.ulcerans_Agy99           TFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEEAEGHDF
MLBr_02226|M.leprae_Br4923          TFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAF
                                        .   :  * .        .             : :*     :.. :

Rv0457c|M.tuberculosis_H37Rv        VWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPPAK
Mb0466c|M.bovis_AF2122/97           VWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPPAK
MMAR_0779|M.marinum_M               VWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFELPEAK
Mflv_0127|M.gilvum_PYR-GCK          VWAGADVLEPTHSVALISLSRGGADAAVVREFDMRTRTFVDGGFELAEAK
Mvan_0785|M.vanbaalenii_PYR-1       VWAGADVIEPDHSLALISLSRGGSDAAVVREFDMRTREFVTGGFELSEAK
MAB_4130|M.abscessus_ATCC_1997      VWAGAAVLRPDFQRALVSLSRGGSDAVVVREFDLETRQFVAGGFELPEAK
TH_3439|M.thermoresistible__bu      VWAGATVIEPDFSLALIELSRGGADATVVREFDMVTKQFVKDGFELPEAK
MSMEG_0899|M.smegmatis_MC2_155      VWSGAEVIEPEYTLALISLSRGGADAVVTREFDMRTRAFVTDGFHLPEAK
MAV_0727|M.avium_104                FALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EIADIA
MUL_0498|M.ulcerans_Agy99           FALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EIADIG
MLBr_02226|M.leprae_Br4923          FALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EIVGIG
                                    .  *:  :          :.  * :    *  *: *     .  .:    

Rv0457c|M.tuberculosis_H37Rv        SQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFEGA
Mb0466c|M.bovis_AF2122/97           SQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFEGA
MMAR_0779|M.marinum_M               SQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMIFQGA
Mflv_0127|M.gilvum_PYR-GCK          SQVSWEDENTLLIGTDFGAGSLTESGYPRLVKRWRRGQALTDAETLFSGA
Mvan_0785|M.vanbaalenii_PYR-1       SQVSWEDADTLLVGTDFGEGSLTESGYPRLVKRWRRGQPLAEAETVFSGS
MAB_4130|M.abscessus_ATCC_1997      TQISWVDADTVYVGTDFGPGSLTDSGYPRLVKRWKRGQSLDDAELVFSGE
TH_3439|M.thermoresistible__bu      TTIAWQDRDTVLVGTDFGPGSLTESGYPRIAKRWRRGRPLEEAETIFEGE
MSMEG_0899|M.smegmatis_MC2_155      SSTSWEDENTLLVCTDFGPGSMTESGYPRVAKRWRRGEPLENAETVYEAE
MAV_0727|M.avium_104                AGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAG-SGEAPELVYHEA
MUL_0498|M.ulcerans_Agy99           AGATWAADHRTVYYITVD-----AAWRPDTVWRYRLG-SPGSSERVYHEP
MLBr_02226|M.leprae_Br4923          AGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLG-SGQPSEQVYHEA
                                    :   *   .       ..      :  *    * : * .   .* ::   

Rv0457c|M.tuberculosis_H37Rv        GTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGS-ELIRIEAPTDA
Mb0466c|M.bovis_AF2122/97           GTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGS-ELIRIEAPTDA
MMAR_0779|M.marinum_M               HTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGT-ELIPLDVPTDA
Mflv_0127|M.gilvum_PYR-GCK          ESDVLVAGSRDHTPGFERTLIARAFDFFNEQVYELRGG-ELIRIDTPTDA
Mvan_0785|M.vanbaalenii_PYR-1       ESDVVVAGSRDRTDGFERTLVSRALDFFNEQVYELRDG-ELIRIDTPTDA
MAB_4130|M.abscessus_ATCC_1997      ASDVTVGASFDDTPGFERTLISRATDFFNSEVHELTADGELLRIDVPTDA
TH_3439|M.thermoresistible__bu      VTDVSVSAGYDATPGYERLVVGRSIDFFNRRRFELRDG-ELIEIKVPTDA
MSMEG_0899|M.smegmatis_MC2_155      PTDIRVIAGVDRTPGYEHTRLGRYTDFYNRVRYEVRDG-ELVLIDVPTDS
MAV_0727|M.avium_104                DEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLPRRDG
MUL_0498|M.ulcerans_Agy99           DERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRREG
MLBr_02226|M.leprae_Br4923          DERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDG
                                       .    .   :  :     .                 ::  :    :.

Rv0457c|M.tuberculosis_H37Rv        S-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSAE
Mb0466c|M.bovis_AF2122/97           S-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSAE
MMAR_0779|M.marinum_M               SSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSGTSD
Mflv_0127|M.gilvum_PYR-GCK          S-ISLHREWLLIELRTEWQ------HLGHTYPAGSLLAADYEEFLAGAAE
Mvan_0785|M.vanbaalenii_PYR-1       S-ISIHRQWLLIELRTDWS------YRFQNYPAGSLLAADYEEFLDGRGE
MAB_4130|M.abscessus_ATCC_1997      S-ASIHREWLLIELKSSWQ------VGDIEYSAGTLLAARYRDYVAGDRT
TH_3439|M.thermoresistible__bu      G-VSVHRDWLLIRLRSEWT------VGSTTYPAGCLLAARYDDYLAGTAD
MSMEG_0899|M.smegmatis_MC2_155      T-LSLHQEWMLIALRTEWQ------VGEVTYPAGSLLATTFDEYLSGARD
MAV_0727|M.avium_104                VEYSVEHA---VVGGQDRF--------LILHNDGAVNFTLTEAPVSDPTR
MUL_0498|M.ulcerans_Agy99           VEYSVEHA---VIGGQDRF--------LILHNDGAVNFTLVEAPVDDPTR
MLBr_02226|M.leprae_Br4923          IEYSVEHAPSGLVGGQDRF--------LILHNDGAVNFTLVESPVSNPEQ
                                       *:.:    :    .             :  * :  :     : .   

Rv0457c|M.tuberculosis_H37Rv        LQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRREP
Mb0466c|M.bovis_AF2122/97           LQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRREP
MMAR_0779|M.marinum_M               LHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWRREP
Mflv_0127|M.gilvum_PYR-GCK          LQVVFTPDAHTCLHHYAWTRDRLVVVTLADVASRVEVYTP---GEWTSEP
Mvan_0785|M.vanbaalenii_PYR-1       VQVVFTPDAHTCLHHYAWTRDRLVVVTLADVASRVQVYTP---GTWTAEP
MAB_4130|M.abscessus_ATCC_1997      LTPVFVPDEHASLHHYAWTRDRLTVAILRDVASEILVFTP---GSWRSEP
TH_3439|M.thermoresistible__bu      LAVVFEPDPHTSLETFAWTRDRLVMISLVDVVSRVEVVTP---GSWERTQ
MSMEG_0899|M.smegmatis_MC2_155      LTIVYEPDPHSCLSSFSWTKDKLILVTLRDVVSHIEIVTP---GTWERRD
MAV_0727|M.avium_104                QRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYARPE
MUL_0498|M.ulcerans_Agy99           QRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYGEVE
MLBr_02226|M.leprae_Br4923          QRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPE
                                       :     .  *         * :     . ..: :      * :    

Rv0457c|M.tuberculosis_H37Rv        LSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRLA
Mb0466c|M.bovis_AF2122/97           LSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRLA
MMAR_0779|M.marinum_M               IAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATTQLE
Mflv_0127|M.gilvum_PYR-GCK          VHGLPENTNTVIVAADD--LGDEIFLDSSGFDTPSRLLYGTG---GGELA
Mvan_0785|M.vanbaalenii_PYR-1       VADLPQNTNTTIAAADP--LGDEIFLDSSGFDTPSRLLHGTA---GGPLS
MAB_4130|M.abscessus_ATCC_1997      LPGVPDNATTQIVAIDD--LGDEIFLDTSGFTQPSTLLRGEVGPAGASVS
TH_3439|M.thermoresistible__bu      VAGIPPNTNTMLVDADE--FGDEIFLDSSGFDTPSRLLWGRA---GGEIT
MSMEG_0899|M.smegmatis_MC2_155      APDIPPVASTVVVDADH--LGDEVFYDSSGFTSPSRLLYGTA---GGPLV
MAV_0727|M.avium_104                EISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGERTLL
MUL_0498|M.ulcerans_Agy99           DVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGERTLL
MLBr_02226|M.leprae_Br4923          EISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTLL
                                       .           :      ..   :..:  *  :           : 

Rv0457c|M.tuberculosis_H37Rv        EIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLLNGY
Mb0466c|M.bovis_AF2122/97           EIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLLNGY
MMAR_0779|M.marinum_M               QIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSDGPGPTLLYGY
Mflv_0127|M.gilvum_PYR-GCK          EIKRAPSFFDAADLEVSQFFATSDDGTEIPYFVVGHRHRQGPGPTLLGGY
Mvan_0785|M.vanbaalenii_PYR-1       EIKQAPSFFDSADLEVSQYFATSDDGTRVPYFVVGHRHRQGPGPTLLGGY
MAB_4130|M.abscessus_ATCC_1997      PIKTAPSFFDDAAFEVAQHFARSDDGTSIPYFVVRAKGSEAAGPTLLGGY
TH_3439|M.thermoresistible__bu      EIKRAPSFFDTADLAVSQHFAISDDGTRIPYFVVGQRHKKIPGPTLLSGY
MSMEG_0899|M.smegmatis_MC2_155      QLKSAPAFFDADGIEVEQFFATSDDGTQVPYFVVGRRSE--PAPTYLYGY
MAV_0727|M.avium_104                REQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIEFPAPALIYGY
MUL_0498|M.ulcerans_Agy99           REQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQLPAPAMIYAY
MLBr_02226|M.leprae_Br4923          REQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGY
                                      : .   :        : :* ::*** :*  :*       ..*: : .*

Rv0457c|M.tuberculosis_H37Rv        GGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMREGR
Mb0466c|M.bovis_AF2122/97           GGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMREGR
MMAR_0779|M.marinum_M               GGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMREGR
Mflv_0127|M.gilvum_PYR-GCK          GGFEVSRTPGYDGVMGRLWLSRGGTYVLANIRGGGEYGPTWHTQAMREGR
Mvan_0785|M.vanbaalenii_PYR-1       GGFEVARTPGYDGVLGRLWLARGGTYVLANIRGGGEYGPTWHTQAMREGR
MAB_4130|M.abscessus_ATCC_1997      GGFEVARTPGYDGVLGRLWLSRGGTYVLANIRGGGEYGPVWHTQAMREGR
TH_3439|M.thermoresistible__bu      GGFEVSNTPSYSGVLGRLWLSRGGTYVLANIRGGGEYGPTWHTQAMRENR
MSMEG_0899|M.smegmatis_MC2_155      GGFQSAQTPGYGGGIGRAWLSRGGTFVQANIRGGGEYGPQWHTQAMRENR
MAV_0727|M.avium_104                GAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKLLEK
MUL_0498|M.ulcerans_Agy99           GAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLLQK
MLBr_02226|M.leprae_Br4923          GAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEK
                                    *.:: .  * :.       * **  :. *::***** *  *: :.    :

Rv0457c|M.tuberculosis_H37Rv        DKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGA
Mb0466c|M.bovis_AF2122/97           DKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGA
MMAR_0779|M.marinum_M               HKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEKFGA
Mflv_0127|M.gilvum_PYR-GCK          HLVYEDFAAVAKDLVARGITTVEQLGAQGGSNGGLLMGVMLTRYPDLFGA
Mvan_0785|M.vanbaalenii_PYR-1       HLVAEDFASVARDLAARGITTVEQLGAQGGSNGGLLMGIMLTKYPELFGA
MAB_4130|M.abscessus_ATCC_1997      HLVYEDFAAVARDLVARGITTAAQLGAQGGSNGGLLMGVMLTAYPELFGA
TH_3439|M.thermoresistible__bu      HLVYEDFAAVARDLVERGVTTVEQLGAQGGSNGGLLMGVMLTRYPELFGA
MSMEG_0899|M.smegmatis_MC2_155      HLVYEDFAAIAADLVRRGITTVDQLGASGGSNGGLLMGVMLTQYPELFGA
MAV_0727|M.avium_104                KNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPELFAG
MUL_0498|M.ulcerans_Agy99           KNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPELFAG
MLBr_02226|M.leprae_Br4923          KNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTG
                                    . .  ** : * .*.  . *   .* * *** ****:* : .  *: * .

Rv0457c|M.tuberculosis_H37Rv        LVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISEYSPYQN
Mb0466c|M.bovis_AF2122/97           LVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD----WKFISEYSPYQN
MMAR_0779|M.marinum_M               LVCNVPLLDMKRYHLLLAGASWVAEYGDPDNPDD----WAFISEYSPYQN
Mflv_0127|M.gilvum_PYR-GCK          LVCSVPLLDMKRFHLLLAGASWMAEYGNPDDPDD----WAFISEYSPYQN
Mvan_0785|M.vanbaalenii_PYR-1       LVCSVPLLDMKRFHLLLAGASWVAEYGDPDNPDD----WAFISEYSPYQN
MAB_4130|M.abscessus_ATCC_1997      LVCQVPLLDMRRYHLLLAGASWVAEYGDPDNPED----WEFISKYSPYQN
TH_3439|M.thermoresistible__bu      LVCSVPLLDMRRFHLLLAGASWVAEYGDPDNPDD----WEFISEYSPYHN
MSMEG_0899|M.smegmatis_MC2_155      LVCSVPLLDMKRFHLLLAGASWVAEYGNPDDPAD----WEFISKYSPYQN
MAV_0727|M.avium_104                ILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLADKDVYFYMKSYSPYEN
MUL_0498|M.ulcerans_Agy99           ILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEVYAYMKSYSPYEN
MLBr_02226|M.leprae_Br4923          ILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYEN
                                    ::..**::*     *  : .  ::*:.: .:*      : ::..****.*

Rv0457c|M.tuberculosis_H37Rv        ISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYENIE
Mb0466c|M.bovis_AF2122/97           ISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYENIE
MMAR_0779|M.marinum_M               ISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVWYYENIE
Mflv_0127|M.gilvum_PYR-GCK          ISADRRYPPVLITTSTRDDRVHPGHARKMTAALEAA---GHPVSYYENIE
Mvan_0785|M.vanbaalenii_PYR-1       ISADRRYPPVLITTSTRDDRVHPGHARKMTAALEAA---GHPVRYYENIE
MAB_4130|M.abscessus_ATCC_1997      ISMDRRYPPVLVTTSTRDDRVHPGHARKMTAALQEA---GQPVWYYENIE
TH_3439|M.thermoresistible__bu      ISTDRSYPPILITTSTRDDRVHPGHARKMTAALEEA---GHRVHYYENIE
MSMEG_0899|M.smegmatis_MC2_155      ISADGKYPPILITTSTRDDRVHPGHARKMTAALEAA---GHRVYYYENIE
MAV_0727|M.avium_104                VDAR-RYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFLLKTQMN
MUL_0498|M.ulcerans_Agy99           VADR-RYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVLLKTQMN
MLBr_02226|M.leprae_Br4923          VEAK-QYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMA
                                    :     **.::  ** .* **:  .. *  ***. :   *  .    :: 

Rv0457c|M.tuberculosis_H37Rv        GGHAGAADNAQIAFKSALSFAFLWRMLAG------------------
Mb0466c|M.bovis_AF2122/97           GGHAGAADNAQIAFKSALSFAFLWRMLAG------------------
MMAR_0779|M.marinum_M               GGHGGAADNEQLAFKSALSYSFLWRMLGSRK----------------
Mflv_0127|M.gilvum_PYR-GCK          GGHAGASDNPQVAFRSALVYEYLLRTLGG------------------
Mvan_0785|M.vanbaalenii_PYR-1       GGHAGASDNPQIAFRSALIYEFLHRTLNGN-----------------
MAB_4130|M.abscessus_ATCC_1997      GGHGGAANNEQSAFKAALAIEFLWRQLAP------------------
TH_3439|M.thermoresistible__bu      GGHAGAADNAQTAFRAALIYEFLHRTVGAAPADG-------------
MSMEG_0899|M.smegmatis_MC2_155      GGHGGAADNKQAAFKGALTYEFLWRMLTGGNLD--------------
MAV_0727|M.avium_104                AGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPDPQG
MUL_0498|M.ulcerans_Agy99           AGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG------------
MLBr_02226|M.leprae_Br4923          AGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG
                                    .**.* :.. :   . *    :*