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KSCPAMCYEFRMSSAPEQPTPATPGTTAFHDLDEFLALPRVAGLAVSPDGTRVVTTVSRLDDKRTEFVSA LWELDPSGQQPARRLTFGAKGESAPEFTADGDLLFLAARPTGDDDEPTRKALWRLPAAGGEAHEVATLPG GVDRVTSAREAATTLITSAMLASATDVDDDKRLRAARKDNKVSAVLHAGYPVRYWDHDLGPEQPHLFDIT EERPRDLTPTPGQALREAHFDLSRDGAFLVTTWQGPAPGAALRTTLVHVDVATGRRTTIVDDRDADLGNP AVSPDGQSVAYTRETISTPRKAPRITLCLLRFGEEPVELTTGWDRWPTSVTWSADGSSVIITADDHGRGP IFAVDPDTGAVRTLVADDFTYSDVRPAPGGVLFALRSSYAAPQHPVRIDADGTVTVLDCVALPDLPGTLT EVTATTADGRTVRSWMVLPHGEAAGSYSSRERSSAPLLLWIHGGPLASWNAWHWRWNPWVMAARGYAVLL PDPALSTGYGQEFIQRGWGSWGFAPYTDLMAATDAACAHPRVDETRTAAMGGSFGGYMANWIAGHTDRFA AIVTHASLWALDQFGATTDGGYWWAREMTPEMAAANSPHLFVSQIATPMLVIHGDKDYRVPIGEALRLWY ELLSSSALPAADDGSTEHRFLYFPSENHWVLSPQHAKIWYQVVLAFLAHHVLGQDSELPEMLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3954 | - | - | 100% (694) | peptidase S9 prolyl oligopeptidase |
| M. vanbaalenii PYR-1 | Mvan_5922 | - | 7e-21 | 25.14% (708) | peptidase S9 prolyl oligopeptidase |
| M. vanbaalenii PYR-1 | Mvan_4095 | - | 2e-10 | 24.27% (342) | peptidase S9 prolyl oligopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2627 | - | 0.0 | 75.51% (686) | peptidase S9 prolyl oligopeptidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4725 | - | 3e-23 | 32.74% (281) | peptidase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4633 | - | 0.0 | 68.40% (674) | peptidase S9, prolyl oligopeptidase |
| M. thermoresistible (build 8) | TH_4519 | - | 2e-10 | 22.16% (379) | PUTATIVE peptidase S9, prolyl oligopeptidase active site domain |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3954|M.vanbaalenii_PYR-1 MKSCPAMCYEFRMSSAPEQPTPATPGTTAFHDLDEFLALPRVAGLAVSPD
Mflv_2627|M.gilvum_PYR-GCK ------------MTAAPD-PNPVSP--TPFHDLDEFLSLPRVSGLAVSRD
MSMEG_4633|M.smegmatis_MC2_155 ------------MN------------STPFHDLDAYLDLPRVSGLAVSPD
MAB_4725|M.abscessus_ATCC_1997 ------------------------MGLPKLITVEEFFEPPVRTSASISPD
TH_4519|M.thermoresistible__bu ----------------------------------VAEQVRATYGASLSPD
. ::* *
Mvan_3954|M.vanbaalenii_PYR-1 GTRVVTTVSRLDDKRTEFVSALWELDPSGQQPARRLTFGAKGESAPEFTA
Mflv_2627|M.gilvum_PYR-GCK GARVVTTVATLNDTRTEFVSALWELDPVGREPARRITRGVTGESAPEFTA
MSMEG_4633|M.smegmatis_MC2_155 GTRVVTTVSTLNAKRTEFVTALWELDPAGQQPARRLTRGLKGESAPVFTA
MAB_4725|M.abscessus_ATCC_1997 GTMIAYLAPRKNR------LNVWVQG-IGSTEARCVTHDETRSVTGFFWV
TH_4519|M.thermoresistible__bu ATAFAHLVDDGGFPR----AVQRFLRGWRASSSRDVELPVVGPVRRVLHS
.: .. . . :* : :
Mvan_3954|M.vanbaalenii_PYR-1 DGDLLFLAARPTGDDDEPTRKALWRLPAAGGEAHEVATLPGGVDRVTSAR
Mflv_2627|M.gilvum_PYR-GCK DGDLLFLAARPTADDDKPP-KSLWCLPVAGGEAYEVCQMPGGVDGVASA-
MSMEG_4633|M.smegmatis_MC2_155 DGDVLFLAVRPTEDDEKPP-AALWRLPAHGGEAHEMLSLPGGVSAAASAR
MAB_4725|M.abscessus_ATCC_1997 DDPRWLLYVQDSGGDENWH-LYRVDLSTPDATAVDLTPFPGARLLGLERP
TH_4519|M.thermoresistible__bu PDGGWLACEVAPDGSDRSQ-IWVVTTDPDDRGAHRIDSWPPDAPEGAAEL
. : . ..:. . * : *
Mvan_3954|M.vanbaalenii_PYR-1 EAATTLITSAMLASATDVDDDKRLRAARKDNKVSAVLHAGYPVRYWDHD-
Mflv_2627|M.gilvum_PYR-GCK -GGATVVVSSMLPSAVDIDADERLRTARKDNKVSALLHTGYPVRAWDHD-
MSMEG_4633|M.smegmatis_MC2_155 TADVTVVAAPLLPSAADVEADRSLRKARKDNKVSAILHTGYPVRQWDHD-
MAB_4725|M.abscessus_ATCC_1997 YGRSGKVYIQLNHRRIDQIDLYELDIASGELTMLAENPGGVMAWFCGPNH
TH_4519|M.thermoresistible__bu IAWDGNRIAAILTGQDGVGSSCLIDPADGSTVVLDRRSGGRLVDAWAGAA
. : . : * . : * .
Mvan_3954|M.vanbaalenii_PYR-1 --LGPEQPHLFDITEERPRDLTPTPGQALREAHFDLSRDGAFLVTTWQGP
Mflv_2627|M.gilvum_PYR-GCK --IGPARTHLFDADTKR--DVTPDPGDALRDSHFDVSPDGGFLVASWNVP
MSMEG_4633|M.smegmatis_MC2_155 --LGPDLPHLFDADGAR--NLTERPGVALRESTFDVSPDGAFVVATWHVP
MAB_4725|M.abscessus_ATCC_1997 EVFAQSLTPGGDIEFSRYESGALRPLCVYDGADYPVGMNPTQMTPDGSGM
TH_4519|M.thermoresistible__bu LIRVGPRGYRELIMLHGNTEMALLPSDPGSTTDFGVILDDHSARRLRRGP
. : * : : : :
Mvan_3954|M.vanbaalenii_PYR-1 APG---AALRTTLVHVDVATGRRTTIVDDRDADLGNPAVSPDGQSVAYTR
Mflv_2627|M.gilvum_PYR-GCK APG---AALRSTLVRIDVNTGDRAVIVDDPESDAGFPAIAPDGTSVAYLR
MSMEG_4633|M.smegmatis_MC2_155 APG---AATRSTLVRIDRETGARTTIAEDPQADLEHPVIAPDGGALAFTR
MAB_4725|M.abscessus_ATCC_1997 WLGSSRDTDRTRLVRLDLATGAESTIDSHPAYDLAAALGLPP----TLIR
TH_4519|M.thermoresistible__bu DGE-----LTKLYQPAKRYPRESTEGYVRALIRSDNGAGYARLLEVTTTA
. . . : . :
Mvan_3954|M.vanbaalenii_PYR-1 ETISTPRKAPRITLCLLRFGEEP------VELTTGWDRWPTSVTWSADGS
Mflv_2627|M.gilvum_PYR-GCK ETLSTPHHAPRITLALLHFGEEP------RELTAHWDRWPTSVTWSADGS
MSMEG_4633|M.smegmatis_MC2_155 ETHSTPTEPPRITLCCMRFGNDDEQLGEWAEVATEWDRWPSSLAWSADAS
MAB_4725|M.abscessus_ATCC_1997 HRKSGELLAARYLGARQEI----------RVLDPDFGPVLEKLQELSDGD
TH_4519|M.thermoresistible__bu DGVAYQVVAERPGHDLDEF-----------VVSDDLSTVALLWNIDGASE
. : . * .: : . . ..
Mvan_3954|M.vanbaalenii_PYR-1 SVIITADDHGRGPIFAVDPDTGAVRTLVADDFTYSDVRPAPGGVLFALRS
Mflv_2627|M.gilvum_PYR-GCK TLLVTADDDGRGPIFAVDPQTGAVRTLVSDDYTYTDVRAAPGGVIFALRS
MSMEG_4633|M.smegmatis_MC2_155 ALIVTADDNGRGPVFSVHPDTGTVTRLTDDDHTYTDVCPAPGGIIYALRS
MAB_4725|M.abscessus_ATCC_1997 LAEVSSDEDGRRWVVSFTHDR-------------------DPGVTYFYDH
TH_4519|M.thermoresistible__bu LQILQYADNTLSEPIPLPGMVAG------------ELSISAGGSMVAMTV
: :. ... *
Mvan_3954|M.vanbaalenii_PYR-1 SYAAPQHPVRIDADGTVTVLDCVALPDL---PGTLTEVTATTADGRTVRS
Mflv_2627|M.gilvum_PYR-GCK SYAAPQHPVRIDPDGTITVLDCVPLPSL---PGTLTEIEATAADGQRVRS
MSMEG_4633|M.smegmatis_MC2_155 SYAVPPHPVRIDPDGTVTELPCFDAPAL---PGSLTEITATAEDGTPVRS
MAB_4725|M.abscessus_ATCC_1997 ATGESHQLFRPYP---------HLDPAD---LAPVVPVTITARDGLTLNS
TH_4519|M.thermoresistible__bu ESPWLPPTVELVDPRTRQWELIDREPSTGPVTGTPTLERLTARDGLELTG
.. * .. . *: ** : .
Mvan_3954|M.vanbaalenii_PYR-1 WMVLP-HGEAAGSYSSRERSSAPLLLWIHGGPLASWNAWHWRWNPWVMAA
Mflv_2627|M.gilvum_PYR-GCK WLVLP-EGDHP----------APLLLWIHGGPLASWNAWHWRWNPWLMAA
MSMEG_4633|M.smegmatis_MC2_155 WLTLP-ESTDP----------APLVLWVHGGPLGSWNTWHWRWNPWLLTA
MAB_4725|M.abscessus_ATCC_1997 YLTLP-VGTEP--------EGLPLVLVVHGGPWH-RDSWGFDPTVQLLAN
TH_4519|M.thermoresistible__bu WLYRPPTGVQP----------VGAMIFLHGGPEGQSRPGYNEYFPPLLDR
:: * . . :: :**** . ::
Mvan_3954|M.vanbaalenii_PYR-1 RGYAVLLPDPALSTGYGQEFIQRGWGSWGFAPYTDLMAATDAACAHPRVD
Mflv_2627|M.gilvum_PYR-GCK GGYAVLLPDPALSTGYGQEFIERGWGAWGFAPYTDLMAATDAACAHPRID
MSMEG_4633|M.smegmatis_MC2_155 HGYAVLMPDPALSTGYGQDFIARGWGAWGEAPYTDLMAATDAACEHPRVD
MAB_4725|M.abscessus_ATCC_1997 RGYAVLQVNFRGSTGYGKAFTKAAIGEFAGKMHDDLIDAVDWAVEQGYAD
TH_4519|M.thermoresistible__bu -GITVFTPNVRGSGGFGRSFVHADDKENRFRAIDDVADCVHYLVRNGLAP
* :*: : * *:*: * *: ... :
Mvan_3954|M.vanbaalenii_PYR-1 ETRTAAMGGSFGGYMANWIAGHT-DRFAAIVTHASLWALDQFGATTD---
Mflv_2627|M.gilvum_PYR-GCK ETRTAVMGGSFGGYMANWIAGHT-DRFAAIVTHAGLWALDQFGATTD---
MSMEG_4633|M.smegmatis_MC2_155 ASRTAAMGGSFGGYMANWVAGHT-DRFDAIVTHASLWALDQFAPTTD---
MAB_4725|M.abscessus_ATCC_1997 PGRIAIFGGSYGGYSALVGVTFTPDVFAAAVDYVGISNLANFMRTLPPFV
TH_4519|M.thermoresistible__bu ADRIACAGWSYGGYLTQAALAFHPDLFAAGISVCGMSDLTTWYQTTEP--
* * * *:*** : . * * * : .: * : *
Mvan_3954|M.vanbaalenii_PYR-1 ----GGYWWAREMTPEMAA------ANSPHLFVSQIATPMLVIHGDKDYR
Mflv_2627|M.gilvum_PYR-GCK ----GSYWWSREMTPKMAS------ANSPHLFVSDIRTPMLVIHGDKDYR
MSMEG_4633|M.smegmatis_MC2_155 ----GAYWWAREMTPEMMQ------RNSPHRFVDQINTPMLVIHGDKDYR
MAB_4725|M.abscessus_ATCC_1997 RPNLANNWYRYVGDPAVPEQEADMLARSPISRVDRIRTPLLVAQGANDVR
TH_4519|M.thermoresistible__bu --WIAQSSYTEYGHPVADR--DLLERLSPLTHAAAVTAPLLLVHGASDTN
. : * ** . : :*:*: :* .* .
Mvan_3954|M.vanbaalenii_PYR-1 VPIGEALRLWYELLSSSALPAADDG----STEHRFLYFPSENHWVLSPQH
Mflv_2627|M.gilvum_PYR-GCK VPIGEALRLWYDLLSRSGLPAADSGPEAGTTQHRFLYFPSENHWILSPQH
MSMEG_4633|M.smegmatis_MC2_155 VPIGEALRLWYELLTESALPADDNG----DSPHRFLYYPAENHWVLTPQH
MAB_4725|M.abscessus_ATCC_1997 VVQAESDNIVAALRARG-------------VEVEYMVKADEGHGFLNPEN
TH_4519|M.thermoresistible__bu VPPSESIQMHTALERLG-------------RPVKLLMFDDDGHEIVRREN
* .*: .: * . . : :.* .: ::
Mvan_3954|M.vanbaalenii_PYR-1 AKIWYQVVLAFLAHHVLGQDSELPEMLG
Mflv_2627|M.gilvum_PYR-GCK AKLWYQVVLGFLNLHVLGQDADVPELLG
MSMEG_4633|M.smegmatis_MC2_155 AKLWYQVVTAFLDENLRNEPAQWPELLG
MAB_4725|M.abscessus_ATCC_1997 QIDLHRATERFLAQHVGGRQVS------
TH_4519|M.thermoresistible__bu RATLVEAMSHWLMSAFAERRREAS----
.. :* . . .