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MSSLWTDGRIEIASRPDEVAQAHTADVLVVGAGITGLTTAVLLARAGKKVLVVEARHVGACATGNTTGKV SVLQGTKLARIRAKHGPDVLSAYVTGNAEGRDWLIRYHDDHGLAYQREDDHSYAQAESGLSTARDVLAAC REAGVDAQWVDEADVPFPFQGGVRVREQAQLDPVPYLGSLVTELEKHGGTLLQGVRATTVTGTDPVRVRF RLTDTAQDTRDEQFSVTARHCVLATGTPILDRGMFFARVEAKRSYCLAFDVPGDITTPMFLSVDSPTRSV RYAPTAAGSKLIVGGAGHPVGRADNPSKAVAELSHWAALHYPGAVQTHYWSAQDYHPDDEVPFIGPLLPM HESVLVATGFDKWGMTNGVAAALALSARILGGRMDWAQTFASWRLHELRGVPTALQANMKVGLHLANGWL APLTSSAEEPADGTGVVSGPPWRLRATSVVDGVQRTVSPVCPHLGGIVKWNDSDRAWECPLHGSRFAPDG ALLEGPATRGLSGCRPAQLRNVSEGLRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0117 | - | - | 100% (518) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5513 | - | 4e-07 | 23.97% (388) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1755 | - | 3e-06 | 39.24% (79) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0732 | - | 0.0 | 75.30% (502) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2503c | - | 1e-145 | 49.90% (505) | putative iron-sulfur binding oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2749 | - | 1e-169 | 57.56% (509) | FAD dependent oxidoreductase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0637 | - | 1e-179 | 61.86% (506) | iron-sulfur binding oxidoreductase |
| M. thermoresistible (build 8) | TH_1303 | - | 1e-178 | 60.67% (506) | iron-sulfur binding oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0117|M.vanbaalenii_PYR-1 -------------------MSSLWTDGRIE-IASRPDEVAQAH-TADVLV
Mflv_0732|M.gilvum_PYR-GCK -------------------MSSLWTDGRVE-TPSRPDEVAAVR-TADVVV
MAV_2749|M.avium_104 -------------------MTSLWMSERTE-RPWAASQLDQGPASADVIV
TH_1303|M.thermoresistible__bu -------------------MTSLWLADRTN-QPPPPRTLDAGDRRADVVV
MSMEG_0637|M.smegmatis_MC2_155 MSGRSFRFGHDGYREAMTAATSLWLAGRAE-RPTPP-YLDETNCTADVVV
MAB_2503c|M.abscessus_ATCC_199 -------------------MNSIWLEGRSGLVARVPLAPDDTTQTVDIAV
.*:* * . . .*: *
Mvan_0117|M.vanbaalenii_PYR-1 VGAGITGLTTAVLLARAGKKVLVVEARHVGACATGNTTGKVSVLQGTKLA
Mflv_0732|M.gilvum_PYR-GCK VGAGITGLTTALLLARAGKKVVVVEARHIGACATGNTTGKVSVLQGSKLA
MAV_2749|M.avium_104 VGAGITGLMTAALLARAGKDVLVLEARTVGACATANTTAKISLLQGSQLS
TH_1303|M.thermoresistible__bu VGAGITGLITAVLLARGGKDVLVVEAAYVGAGATGNTTAKISVLQGSRMS
MSMEG_0637|M.smegmatis_MC2_155 VGAGITGLITAVLLARAGKDVLVLEAYTAGAGTTGNTTAKVSLLQGTKMS
MAB_2503c|M.abscessus_ATCC_199 IGAGITGLTTALLLARAGLEVVVLEARSAGDGTTGNSTGKISALHGTKLS
:******* ** ****.* .*:*:** * :*.*:*.*:* *:*::::
Mvan_0117|M.vanbaalenii_PYR-1 RIRAKHGPDVLSAYVTGNAEGRDWLIRYHDDHGLAYQREDDHSYAQAESG
Mflv_0732|M.gilvum_PYR-GCK NVAGKHGTDTLRAYVLGNTEGRDWLLRYCDEHGISAQREDDHAYAQNEKG
MAV_2749|M.avium_104 KVLPRHGREVTRAYVDGNREGQEWVLGHCEAHGVAVQREDAYTYAQSVRG
TH_1303|M.thermoresistible__bu KILAKHGPRRARQYVEGNLEGLEWLVRHCAAHGLSVQREDAYTFAQSLQG
MSMEG_0637|M.smegmatis_MC2_155 KILRKHGAKVAGQYVQGNLEGQEWLAGYCDANGLSLQREDAYTYAQSEKG
MAB_2503c|M.abscessus_ATCC_199 RIAHRHGHAVARAYTTGNTEGRDWLLRYCEEHGVPTQTEDAYTYAQTREG
.: :** *. ** ** :*: : :*:. * ** :::** *
Mvan_0117|M.vanbaalenii_PYR-1 LSTARDVLAACREAGVDAQWVDEAD---VPFPFQGGVRVREQAQLDPVPY
Mflv_0732|M.gilvum_PYR-GCK LGTARKILAACREANLDAQWVDEAD---VPFPFAGGVRLREQAQIDPMPY
MAV_2749|M.avium_104 VPSARAEFEACQAVGLPVVWQDDAE---VPFAYHGGVRLADQAQFDPMPF
TH_1303|M.thermoresistible__bu VPAARTEYLAAKIAGLDVEWVDDAEG-GVPFPFHGAVRLADQAQFDPMPL
MSMEG_0637|M.smegmatis_MC2_155 LASARAEYDACREVGLDADWVDAADAPDVPFPFAGGVRLPDQAQFDPMPL
MAB_2503c|M.abscessus_ATCC_199 TAGARDEWNACLQAGLPVRWETTAD---TPFPYYGGVRLPDQAQFNPAQL
** *. ..: . * *: .**.: *.**: :***::*
Mvan_0117|M.vanbaalenii_PYR-1 LGSLVTELEKHGGTLLQGVRATTVTG-TDPVRVRFRLTDTAQDTRDEQFS
Mflv_0732|M.gilvum_PYR-GCK LSSVVAELESHGGTVLQGVRATSVSG-VRSVTVTLRMTTRPDDTRDEDFS
MAV_2749|M.avium_104 LDSLAVELLGRGGRLVEHTRVRRVSWRGKGVRVHANQGS---DAAGHDVE
TH_1303|M.thermoresistible__bu LDSLVVELEERGGRLVQGLRVHKVSGRGDGLTLHARSG------AGDEFD
MSMEG_0637|M.smegmatis_MC2_155 LDKLIVELDERNGRLVEGTRVLGVSQDSSGLKIKVRSH------TGTELD
MAB_2503c|M.abscessus_ATCC_199 VESMVAQLEDHGAHFFSGMRVRSISG-RGPLRIKGDYAH---DAGAGEFA
: .: .:* :.. ... *. :: : : :.
Mvan_0117|M.vanbaalenii_PYR-1 VTARHCVLATGTPILDRGMFFARVEAKRSYCLAFDVPGDITTPMFLSVDS
Mflv_0732|M.gilvum_PYR-GCK ITAERCVLATGIPVLDRGFFFARAEPMRSYCMAFDVPGELTRSMYISVDS
MAV_2749|M.avium_104 LHADQLVLATGIPILDRGGYFARVKPSRSYCLAFKVPGNITRPMMISTDS
TH_1303|M.thermoresistible__bu LRADRCVLATGIPILDRGGFFARLEPNRSYCLAYEVPGEITRGMYISTDS
MSMEG_0637|M.smegmatis_MC2_155 VRAGQCVLATGIPILDRGGFFARLSPHRSYCLAFRVPGAVTRGMYISTDS
MAB_2503c|M.abscessus_ATCC_199 LEAQRCVLATGTPILDRGGFFAKLTANRSYCMSFDVPGPITRAMYLSVDA
: * : ***** *:**** :**: . ****::: *** :* * :*.*:
Mvan_0117|M.vanbaalenii_PYR-1 PTRSVRYAPTAAGSKLIVGGAGHPVGRADNPSKAVAELSHWAALHYPGAV
Mflv_0732|M.gilvum_PYR-GCK PTRSVRYAPTPGGEKLIVGGAGHPVGRADDPKSAVDELGRWATLHYPGAV
MAV_2749|M.avium_104 PTRSVRYAPVPDGERLIVGGAGHTVGREKSPSAALDELSAWTRKHFPGAV
TH_1303|M.thermoresistible__bu PTRSLRYAPTGAGDLLIVGGAGHPVGHEKNPASSVAELDEWARRHFPGAQ
MSMEG_0637|M.smegmatis_MC2_155 PTRSVRYAPTADGDRLIVGGAGHTVGRRSHPSDDVDELASWAKVHWPGAI
MAB_2503c|M.abscessus_ATCC_199 PLRSVRYAPSSTGDRLVVGGAGHVVGHPAHAREALRELAGWAQTHYPGAT
* **:**** *. *:****** **: . : ** *: *:***
Mvan_0117|M.vanbaalenii_PYR-1 QTHYWSAQDYHPDDEVPFIGPLLPMHESVLVATGFDKWGMTNGVAAALAL
Mflv_0732|M.gilvum_PYR-GCK QTHFWSAQDYHPADELPYVGPLLPKLENILVATGFDKWGMTNGVAAALAL
MAV_2749|M.avium_104 QTHFWSAQDYTPIDHLPYVGPILPNSETIFVATGFNKWGMTNGAAAALAL
TH_1303|M.thermoresistible__bu QRYFWSAQDYSPIDDLPYVGPILPGNESIFVAIGFDKWGMTNGAAAALAL
MSMEG_0637|M.smegmatis_MC2_155 QTHYWSAQDYTPVDELPYVGPLLPGNEKVFVATGFDKWGMTNGTAAALAL
MAB_2503c|M.abscessus_ATCC_199 RTHSWAAQDYATISELPYAGPLLPGGKRIYLATGYDKWGMTNGIAASLAL
: : *:**** . ..:*: **:** : : :* *::******* **:***
Mvan_0117|M.vanbaalenii_PYR-1 SARILGGRMDWAQTFASWRLHELRGVPTALQANMKVGLHLANGWLAPLTS
Mflv_0732|M.gilvum_PYR-GCK TSRILGGRMDWARAFASWSPHELSGIPTALQMNFEVGLHLAKGWVTPVTT
MAV_2749|M.avium_104 SSRILGGRMDWARAFASWSPHELSGLATAVQANLEVGFNLTKGWITPAVR
TH_1303|M.thermoresistible__bu SSRILGGRTDWAEAFASWSPHEVSGIPKAMMLNLQVGMYLARGWLTPVTR
MSMEG_0637|M.smegmatis_MC2_155 SSRILGGRMDWSQAFDSWSPHELSGIPTALKVNLEVGFNMAKGWVTPILR
MAB_2503c|M.abscessus_ATCC_199 SSQILGGRMDWANAFASWSALDLRAIPAAIRLGSRVARDFASGWATAMLT
:::***** **:.:* ** :: .:. *: . .*. :: ** :.
Mvan_0117|M.vanbaalenii_PYR-1 S-AEEPADG-TGVVSGPPWRLRATSVVDGVQRTVSPVCPHLGGIVKWNDS
Mflv_0732|M.gilvum_PYR-GCK P-AGPPAEG-EGIVTGPPWNLRACSVVDGVERTVSPVCPHLGGIVEWNNI
MAV_2749|M.avium_104 IGRRSPVDGDGGVVSGPPWHLQARCRVDGTEHRVSPVCPHLGGIVNWNDA
TH_1303|M.thermoresistible__bu TGDRSPDDG-CGVVSGPPWHLQARSRVDGVEHRVSPVCPHLGGIVNWNDA
MSMEG_0637|M.smegmatis_MC2_155 RGDGVPDDG--GVVAGPPWRMEACSVVDGVERRVSPVCPHLGGIVEWNDS
MAB_2503c|M.abscessus_ATCC_199 S-----------------------------RPEHAPVCTHLGGITTWNDA
. :***.*****. **:
Mvan_0117|M.vanbaalenii_PYR-1 DRAWECPLHGSRFAPDGALLEGPATRGLSGCRPAQLRNVSEGLRP
Mflv_0732|M.gilvum_PYR-GCK DHAWECPLHGSRFAPDGTLLEGPATRGLT----------------
MAV_2749|M.avium_104 DKAWECPLHGSRFAPDGTLLEGPATRDLTASR-------------
TH_1303|M.thermoresistible__bu DQAWECPLHGSRFAPDGALLEGPATRGLTAS--------------
MSMEG_0637|M.smegmatis_MC2_155 DEAWECPLHGSRFAPDGTLLEGPATHGLTPAP-------------
MAB_2503c|M.abscessus_ATCC_199 EDIWECPLHGSCFDSGGSVLWGPATEPLDRLPADGAR--------
: ******** * ..*::* ****. *