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MRFGLFIPQGWRLDLVGIDPREQWRVMSDLATYVDAGDAWDSLWVYDHFHTVPVPTDEATHEAWSLMSAY AATTSRVKLGQMCTAMSYRNPAYLAKVAATADVISGGRIQMGIGGGWYEHEWRAYGYGFPSAGTRLARLD EGVQIMRDAWRDGVVSFDGKHYQVDGAIVAPRPLQDGGLPLWIAGGGEKVTLRIAAKYAQYTNFTSEPDG FEHKSRVLAEHCKDVGTDFDAIVRSANINVVVGTSEADVEDRLARVRSRISDLTGEAAADAMLNAMNSPQ AGSGTPEQLVESLQRLRDLGCEYVICYFPEAAYDRSSIEMFEREIMPALA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1696 | - | - | 100% (330) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4098 | - | 3e-39 | 34.48% (290) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1117 | - | 1e-37 | 36.70% (218) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 4e-34 | 36.59% (205) | oxidoreductase |
| M. tuberculosis H37Rv | Rv1855c | - | 4e-34 | 36.59% (205) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 7e-19 | 28.25% (315) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0858 | - | 1e-134 | 68.40% (326) | luciferase-like monooxygenase |
| M. marinum M | MMAR_4673 | - | 1e-157 | 77.58% (330) | hypothetical protein MMAR_4673 |
| M. avium 104 | MAV_0986 | - | 1e-157 | 77.88% (330) | hypothetical protein MAV_0986 |
| M. smegmatis MC2 155 | MSMEG_5715 | - | 1e-157 | 76.97% (330) | hypothetical protein MSMEG_5715 |
| M. thermoresistible (build 8) | TH_4607 | - | 1e-149 | 73.03% (330) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0292 | - | 1e-149 | 76.73% (318) | hypothetical protein MUL_0292 |
| M. vanbaalenii PYR-1 | Mvan_5062 | - | 1e-175 | 86.36% (330) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1886c|M.bovis_AF2122/97 -------------MTIRLGLQIPN----FSYGTGVEKLFPSVIAQAREAE
Rv1855c|M.tuberculosis_H37Rv -------------MTIRLGLQIPN----FSYGTGVEKLFPSVIAQAREAE
Mflv_1696|M.gilvum_PYR-GCK ---------------MRFGLFIPQGWRLDLVGIDPREQWRVMSDLATYVD
Mvan_5062|M.vanbaalenii_PYR-1 ---------------MRFGIFVPQGWRLDLVGIAPRDQWQVMRDLASYVD
MMAR_4673|M.marinum_M ---------------MRFGLFIPQGWRMDLVGIAPEQHWAVMRDLATYAD
MUL_0292|M.ulcerans_Agy99 ---------------------------MDLVGIAPEQHWAVMRDLATYAD
MAV_0986|M.avium_104 MKTVAVRPVRLESRGMRFGLFIPQGWRMDLVGIEPDEHWAVMRDLAQRAD
MSMEG_5715|M.smegmatis_MC2_155 ---------------MRFGLFIPQGWRLDLVDIPTDRHWSVMRDLAAYAD
TH_4607|M.thermoresistible__bu ---------------MRFGLFIPQGWRLDLVDIPPERHWQVMRDLAVYAD
MAB_0858|M.abscessus_ATCC_1997 --------MAQVAETLEFGVFIPQGWRLDLVGIAPERHWDVMRDLVHYAE
MLBr_00269|M.leprae_Br4923 ----------------------MAELRLGYKASAEQFAPRELVELGVAAE
: .:
Mb1886c|M.bovis_AF2122/97 AAG-YDSLFVMDHFYQLPMLGTPDQPMLEAYTALGALATATERLQLGALV
Rv1855c|M.tuberculosis_H37Rv AAG-YDSLFVMDHFYQLPMLGTPDQPMLEAYTALGALATATERLQLGALV
Mflv_1696|M.gilvum_PYR-GCK AGDAWDSLWVYDHFHTVPVP--TDEATHEAWSLMSAYAATTSRVKLGQMC
Mvan_5062|M.vanbaalenii_PYR-1 EGGVWDSLWVYDHFHTVPVP--TAEATHEAWSLMSAYAATTSRIKLGQMC
MMAR_4673|M.marinum_M ASA-WDSLWVYDHFHTVPLP--SDEATHEAWSLMAAYAAVTSRIKLGQMC
MUL_0292|M.ulcerans_Agy99 ASA-WDSLWVYDHFHTVPLP--SDEATHEAWSLMAAYAAVTSRIKLGQMC
MAV_0986|M.avium_104 RDVGWDSLWVYDHFHTVPVP--TGEATHEAWSLMAAYAAVTSRIKLGQMC
MSMEG_5715|M.smegmatis_MC2_155 GSQAWDSLWVYDHFHTVPVP--TGEATHEAWTLMAAYAATTSRIKLGQMC
TH_4607|M.thermoresistible__bu QS-AWDSIWVYDHFHTVPMP--THEATHEAWSLMAAYAASTRSIKLGQMC
MAB_0858|M.abscessus_ATCC_1997 GGP-WDSVWVYDHFHTVPVP--TDEATHEAWTLMSAFAAVTSRIKLGQMC
MLBr_00269|M.leprae_Br4923 AHG-MDSATVSDHFQPWRHQ---GGHASFSLSWMTAVGERTNRILLGTSV
** * *** : : : * . * : **
Mb1886c|M.bovis_AF2122/97 TGNTYR-SPTLLAKIITTLDVVSAGRAILGIGAGWFELEHR-QLGFEFGT
Rv1855c|M.tuberculosis_H37Rv TGNTYR-SPTLLAKIITTLDVVSAGRAILGIGAGWFELEHR-QLGFEFGT
Mflv_1696|M.gilvum_PYR-GCK TAMSYR-NPAYLAKVAATADVISGGRIQMGIGGGWYEHEWR-AYGYGFPS
Mvan_5062|M.vanbaalenii_PYR-1 TAMSYR-NPVYLAKVAATADIISGGRIQMGIGGGWYEHEWR-AYGYGFPS
MMAR_4673|M.marinum_M TAMSYR-NPVYLAKVAATTDIISGGRIQMGIGGGWYEHEWR-AYGYGFPS
MUL_0292|M.ulcerans_Agy99 TAMSYR-NPVYLAKVAATADIISGGRIQMGIGGGWYEHEWR-AYGYGFPS
MAV_0986|M.avium_104 TAMSYR-NPVYLAKVAATADIISGGRIQMGIGAGWYEHEWR-AYGYGFPS
MSMEG_5715|M.smegmatis_MC2_155 TAMSYR-NPVYLAKVAATTDVISGGRVQMGIGGGWYEHEWR-AYGYGFPS
TH_4607|M.thermoresistible__bu TAMSFR-NPVYLAKVAATVDVISGGRVQMGIGAGWYEHEWR-AYGYGFPP
MAB_0858|M.abscessus_ATCC_1997 TAMGYR-NPVYLAKIAATVDIISGGRAQMGIGGGWYEHEWR-AYGYGFPG
MLBr_00269|M.leprae_Br4923 LTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPE
:* .*. :.: :* . : .* :*:* * * :
Mb1886c|M.bovis_AF2122/97 FSDRFNRLEEALQILEPMVKGERPTFFGDWYTTESAMAEPR--YRDRIPI
Rv1855c|M.tuberculosis_H37Rv FSDRFNRLEEALQILEPMVKGERPTFFGDWYTTESAMAEPR--YRDRIPI
Mflv_1696|M.gilvum_PYR-GCK AGTRLARLDEGVQIMRDAWRDGVVSFDGKHYQVDGAIVAPRPLQDGGLPL
Mvan_5062|M.vanbaalenii_PYR-1 AGVRLARLDEGVQIMRDAWRDGTVTFDGKHYQADGAIVAPRPLQQAGIPL
MMAR_4673|M.marinum_M AGTRLGRLDEGVQIMRDAWRDGKVSFDGKHYQVDGAIVAPKPLQNNGIPL
MUL_0292|M.ulcerans_Agy99 AGVRLGRLDEGVQIMRDAWRDGKVSFDGKHYQVDGAIVAPKPLQNNGIPL
MAV_0986|M.avium_104 AGVRLGRLDEGVQIMRDAWRDGKVSFNGRHYQVDGAIVAPKPLQDNGIPL
MSMEG_5715|M.smegmatis_MC2_155 AGERLGRLDEGVQIMRDAWRDGRVSFDGKHYQADGAIVSPTPLQEDGIPL
TH_4607|M.thermoresistible__bu AKVRLGRLDEGVQIMHDAWLNGIVSFDGEHYQVDGAIVEPRPLQDERIPL
MAB_0858|M.abscessus_ATCC_1997 AAERLGRLREGVRIMRDAWRDGRVSLDGTYYQVDDAIVAPTPLQSNGIPL
MLBr_00269|M.leprae_Br4923 FKERFARLRESVRLMRELWRGDRVDFDGDYYQLKGASIYDVP--EGGVPI
*: ** *.::::. . : * * ..* :*:
Mb1886c|M.bovis_AF2122/97 LIGGGGEKKTFAIAARFADHLNIVAAVDELPRK--MRALAARCDEAGRDR
Rv1855c|M.tuberculosis_H37Rv LIGGGGEKKTFAIAARFADHLNIVAAVDELPRK--MRALAARCDEAGRDR
Mflv_1696|M.gilvum_PYR-GCK WIAGGGEKVTLRIAAKYAQYTNFTSEPDGFEHK--SRVLAEHCKDVGTDF
Mvan_5062|M.vanbaalenii_PYR-1 WIAGGGEKVTLRIAAKYAQYTNFTSEPEGFAHK--SQVLAEHCRDVGTDF
MMAR_4673|M.marinum_M WVAGGGEKVTLRIAAQYAQYTNFTPQPEQFAHK--SQVLAEHCRKLGTEF
MUL_0292|M.ulcerans_Agy99 WVAGGGEKVTLRIAAQYAQYTNFTPQPEQFAHK--SQVLAEHCRKLGTEF
MAV_0986|M.avium_104 WIAGGGEKVTLRIAAEYAQYTNFTPESAAFAHK--SEVLAAHCRDVGTDF
MSMEG_5715|M.smegmatis_MC2_155 WIAGGGEKVTLKIAAKYAQYTNFTSEPEAFRRK--SQILAEHCRTVGTDF
TH_4607|M.thermoresistible__bu WIAGGGEKVTLRIAAKYADYTNYTCDPEGFERK--SEILAEHCHDVGTDF
MAB_0858|M.abscessus_ATCC_1997 WIAGGGEKVTLRIAARYAQYTNFGQTAEEFGHK--SRVLAAHCKDIGTDF
MLBr_00269|M.leprae_Br4923 YIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDA
:..** : : . . : : : . * :
Mb1886c|M.bovis_AF2122/97 STLQTSLLLTVMIDETLS-------------------------------P
Rv1855c|M.tuberculosis_H37Rv STLQTSLLLTVMIDETLS-------------------------------P
Mflv_1696|M.gilvum_PYR-GCK DAIVRSANINVVVGTSEADVEDRL----------ARVRSRISDLTGEAAA
Mvan_5062|M.vanbaalenii_PYR-1 DKIVRSANINAVVGSSESDVKDRL----------ARVRSRISALTGEPAA
MMAR_4673|M.marinum_M DAIVRSANFTAVLGTSEADVKDRM----------GRVRDRLVGYVPEAVA
MUL_0292|M.ulcerans_Agy99 DAIVRSANFTAVLGTAEADVKDRL----------GRVRDRLVGYVPEAVA
MAV_0986|M.avium_104 DAIVRSVNVNAVVGASRADVDDRL----------RRIRDRMAGYVGESAA
MSMEG_5715|M.smegmatis_MC2_155 DAIVRSANFNAVIGESEKDVKERI----------ERLRARQSPVAGEDAV
TH_4607|M.thermoresistible__bu EAIVRSANFNAVLGETESEVADRL----------QQVRARLVSRVGEDAA
MAB_0858|M.abscessus_ATCC_1997 DAIVRSANMNIVIGSDAGEVADRL----------AAIKARLVPIIGEDVA
MLBr_00269|M.leprae_Br4923 DDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVA
. : .. .
Mb1886c|M.bovis_AF2122/97 DAIPAEMSGR-VVVGSPAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVI
Rv1855c|M.tuberculosis_H37Rv DAIPAEMSGR-VVVGSPAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVI
Mflv_1696|M.gilvum_PYR-GCK DAMLNAMNSP-QAGSGTPEQLVESLQRLRDLGCEYVICYFPEAAYDRSSI
Mvan_5062|M.vanbaalenii_PYR-1 DAMLNSMSSP-EAGSGTPEQLIDTLRRLRELGCEYVICYFPEAAYDRSGI
MMAR_4673|M.marinum_M DSMVGGLP---DSATGTPEQVIERLAQIRDLGCEYAICYFPEAAYDRSGI
MUL_0292|M.ulcerans_Agy99 DSMVGGLP---DSATGTPEQVIERLAQIRDLGCEYAICYFPEAAYDRSGI
MAV_0986|M.avium_104 DAMIAGTSGV-DSATGTTEQVIERLARLRDLGCDYVICYFPEAAYDRSGI
MSMEG_5715|M.smegmatis_MC2_155 DAMLSTMSAP-ESASGTPEQVIEKLKRVRDLGCEYAILYFPEAAYDRSGI
TH_4607|M.thermoresistible__bu DGMVDSIKAP-SSATGTPDQVIERLQRMRDLGCEYAIMYFPEAAYDRSGI
MAB_0858|M.abscessus_ATCC_1997 EGTVANLA----TTAGTPEQIAERLAEYRGLGLGYAICNFPEAAYDRSGI
MLBr_00269|M.leprae_Br4923 DALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQ-RRFL
:. . .: . * : . :
Mb1886c|M.bovis_AF2122/97 TTAAEALRPLLGV--
Rv1855c|M.tuberculosis_H37Rv TTAAEALRPLLGV--
Mflv_1696|M.gilvum_PYR-GCK EMFEREIMPALA---
Mvan_5062|M.vanbaalenii_PYR-1 ELFEREVIPALS---
MMAR_4673|M.marinum_M ELFEREVIPALS---
MUL_0292|M.ulcerans_Agy99 ELFEREVIPALS---
MAV_0986|M.avium_104 ELFEREIIPALS---
MSMEG_5715|M.smegmatis_MC2_155 ELFEQKVIPALS---
TH_4607|M.thermoresistible__bu EMFEQKVIPALS---
MAB_0858|M.abscessus_ATCC_1997 DLFVREVIGV-----
MLBr_00269|M.leprae_Br4923 ELFEKDLAPRLRRLG
. :