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GSRSAAHGGRSWRSGRHRKQRRIEPYAWLGAGAVTLGIGAAALSGAGIAAADDPSTDSTSTSSSTEDNTS SDPRTPSSTRSTDAEEPSNDKNIEPPGNDSDDEADHEVDTTTETDAAARDGADGVDEEPRRNKGREDGIE TYDPSPSVDKQDNDTEANELTAVVDEDDAPRPRGAESQQRPAVGAVSPALTNTQSAPVPLAPHETTTTQL SPETPENATTTRLLDAPTEPFDSPLAWLLLASSRRQIGRVADEDAHSPAADALAVDAENTAPTAALRGQS SPGWFTGRVTGRVAASDVDGDRLSFTGMTTAKGTVTVTPWGTFTYRPSKAARHAAAATTASDAEKFDTFA ITVSDGNGGWTEVPVTVAVRPVNSSPSWLRSTKTKPNPVSGEVNGRIIAIDRDGDAFTYTASAPGKGAVV VNLDGTFSYTASDSARAAARNTWYTDTDRFIVVVNDGHGGTRSVSVRVEVAPSNNAPTTGAPNLDAPDPG TGAVRGTVNAVDPDGDRITYRRETIMTAKGVLTIGSTGAFNYTPTTAARHAAATSDPNLAADSVTITARD RFGGVGAIVLTIPIAPTNTSPVGSAAGAGVTDPVTGVVRGTVTATDSDGDDLLFSGTTTTEKGSVVVDSI GTYTYTPTTAARHHVNAEDATDADRRDSFVVTVTDGHGGTAQVLVSVAIAPSSNQAPGGVSYSANPNTDT GVVEGRVTATDPEGDSLTFSGSAETGKGTVAVAPDGSFVYTPTDDARLSAGAPGAPVASKEDSFVVDVSD GHGGTTSISVSVEIVPLIDNESPVAGTPIVGDPTPGTGVVSGTLGFTDPEGSSLAYTVTGPPAKGLVSID TTGGFTYTPNPEDRPEAGEAPGYDAFTVVATDPQGLAAQVTVDVVVAPLLPPSDGPVVGTPPYDIDSVDE VTGVISGHVTAYTSNGTALTFAVAESPDVASGRVALDSATGRWTFTPTASTLVSAWSSDTPTPVTFTIRV SDGEKSTDITVSATVSPSEQAVINSVEYLGSEPSGVTVGPDGRMYVIDSGANTLSIINPADASMITVTVG KNPTSVASDDLGRLWVTNSGDHTVTVLNAEAEILRTVQVGLVPASVVIRGDLAYIANFGGNSLSVIDAAD DYSVRSVDVGTNPIDIAIGSDGRIYVANFGNGTISVLRPDDMDDVLLVDSGGEHPHGILVDDDGTVYVTH PLDDTVTVLNPAPVNRFSLRSLFSADATSGQYTYRSVTVIGAPTKITKDTAGRIYVTNSSGATITVLDPL TLAANEIHTGANPSSVYVDRFGNLYVTNAGQKTVAVIHAQTRNITTYRADVKTSQVTTDDDGNLVMVSTY DGHRSVLSTDTVSTGADALQIANVWGSYGSLVASPDGKWLYAVRNRRVDTTGGLYPNRYDIVAIDTSNNS VRTFAWDAHINGSMVLTMNRDGDRLYAAYYTLDPEVFDGVVAKVAIINVDGSTLQLDGAPVELNLGSTTA FVSDIVVNPAGTKVFVIGDRLAVPGQWDAPEGQWNMYGNLWMVDLENDRAVSRPPIPRPLQAEGGVPDLA ISPDGRYAYLVMTPLPGWEGNHYLGIFDTQSFALTTVLLGHFEAPNGVRRLVVSPDGTRIYLSDGQIVGV TGTQHELLEDRIQGIDQERFVDIAINPEGTRLYTTTWDGVLTTIDTSTGLPVGNPTDLGNRAWGMTFGPK GDTLYVRRGVDYVASHRAPQSIADLWENVRDLPNGDNEGIFTQVVRHADGTNRMVVYLGGTNPRNWLVGE QAIGENVVSELGILKDEHLGAITRALAHCRNDATCGDIADVMLVGFSQGGIDGQNFASQWDRLGFGVQLS ALVTFGSPITKNPNVPTLHIQDIDDEVVNTELLARLAATVQYVPMPSWLRINFAAATVTAMARGQLYQGA ADTDISVLDIFAVHGNRATYQQLASEMDARTGTDFAALGPVRTFFGGTALIPGDPTPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1720 | - | - | 100% (1949) | YVTN beta-propeller repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5913 | - | e-133 | 48.09% (549) | putative outer membrane adhesin like proteiin |
| M. vanbaalenii PYR-1 | Mvan_3594 | - | 1e-98 | 40.88% (548) | YVTN beta-propeller repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1006c | PE_PGRS18 | 2e-15 | 33.13% (163) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_2913 | - | 2e-88 | 40.11% (551) | YVTN beta-propeller repeat-containing protein |
| M. tuberculosis H37Rv | Rv0980c | PE_PGRS18 | 1e-15 | 31.28% (195) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4577 | pknD | 5e-15 | 26.14% (417) | transmembrane serine/threonine-protein kinase D PknD |
| M. avium 104 | MAV_4238 | - | 1e-11 | 24.93% (345) | serine/threonine-protein kinase PknD |
| M. smegmatis MC2 155 | MSMEG_4365 | - | 3e-12 | 28.66% (328) | hypothetical protein MSMEG_4365 |
| M. thermoresistible (build 8) | TH_0100 | - | 4e-09 | 26.13% (333) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0230 | - | 3e-06 | 23.94% (355) | hypothetical protein MUL_0230 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 MGSRSAAHGGRSWRSGRHRKQRRIEPYAWLGAGAVTLGIGAAALSGAGIA
Mflv_2913|M.gilvum_PYR-GCK --------------------MRHSACIGRIGALAFALGVGIGLGATPAVA
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------MGRIGALAVALGIGAALTTGTGVA
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 AADDPSTDSTSTSSSTEDNTSSDPRTPSSTRSTDAEEPSNDKNIEPPGND
Mflv_2913|M.gilvum_PYR-GCK LADETASSSASSEGGPSK--PQRPASESSGAESDSSDTDTGASHDTNVDT
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 WADDSGASGGSTS-------SSSSASDSSSSSAGGSSGSASGGADAAKPR
Mb1006c|M.bovis_AF2122/97 ------------------------------------------------MS
Rv0980c|M.tuberculosis_H37Rv ------------------------------------------------MS
MMAR_4577|M.marinum_M -----------MSETGPGSRVGSRFGPYELVRLIGRGGMGEVYEAEDTRK
MAV_4238|M.avium_104 -----------MSDNGPAAQVGSWFGPYRLVRLLRQGGMGEVYEAEDTRK
TH_0100|M.thermoresistible__bu ---VTVIGAQQVVDIALAEAARRGKADETMVLVTDRADASLRWAGNSMTT
Mvan_1720|M.vanbaalenii_PYR-1 SDDEADHEVDTTTETDAAARDGADGVDEEPRRNKGREDGIETYDPSPSVD
Mflv_2913|M.gilvum_PYR-GCK DADAEDRAADADADADVTEVDPEDSTRATPISVQDEATEVDVAEEPEPAD
MUL_0230|M.ulcerans_Agy99 ---------------------MSDVNGQQTGWNDRDGGDVQVFELGTAPD
MSMEG_4365|M.smegmatis_MC2_155 KPGVTKPRIQPTGKIAESLKKTAKAVEGAVADAHKRAQQSAAQQAEKRAE
Mb1006c|M.bovis_AF2122/97 F---VNVAPQLVSTAAADAA------------------------------
Rv0980c|M.tuberculosis_H37Rv F---VNVAPQLVSTAAADAA------------------------------
MMAR_4577|M.marinum_M R---RVVALKLISTQYSGNP------------------------------
MAV_4238|M.avium_104 H---RLVALKLISQQFSGNP------------------------------
TH_0100|M.thermoresistible__bu NGESVSRTTTVVSVVRRENS------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 KQDNDTEANELTAVVDEDDAPRPRGAESQQRPAVGAVSPALTNTQSAPVP
Mflv_2913|M.gilvum_PYR-GCK SAPALGVPTEAPSPAPEPTN------------------------------
MUL_0230|M.ulcerans_Agy99 FPTSVEIAVANGPIGDIGIS------------------------------
MSMEG_4365|M.smegmatis_MC2_155 RRAKLRAQIRPGKDTDKQAP------------------------------
Mb1006c|M.bovis_AF2122/97 -----RIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSH-------
Rv0980c|M.tuberculosis_H37Rv -----RIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSH-------
MMAR_4577|M.marinum_M -----TFRARMQREADTAGRLTEPHIVPIHDYGEIDDQFFVEMRLIDGVS
MAV_4238|M.avium_104 -----EFSARLQREADIAGRLTEPHVVPIHDYGEIDGRFFVEMRLVDGID
TH_0100|M.thermoresistible__bu -----THVASVRSSEVDPAAIPALVAASQDAALTAPEARDSAPPLPGDTT
Mvan_1720|M.vanbaalenii_PYR-1 LAPHETTTTQLSPETPENATTTRLLDAPTEPFDSPLAWLLLASSRRQIGR
Mflv_2913|M.gilvum_PYR-GCK --PQAEATVDIPAPPSEEQTPAPMPAPTAVTLSSILSSLLTPTDTPNTPA
MUL_0230|M.ulcerans_Agy99 -----PDGSRLMVTNYGDNSVSVIDTDTCRVVETITG-------------
MSMEG_4365|M.smegmatis_MC2_155 --EKQAGNEAKNAAQPATKTQRQLPAAPAVKVPDVITSVRARS-------
.
Mb1006c|M.bovis_AF2122/97 -----GQHYQAISAQVAAYQERFVLALSQASST-----------------
Rv0980c|M.tuberculosis_H37Rv -----GQHYQAISAQVAAYQERFVLALSQASST-----------------
MMAR_4577|M.marinum_M LRAMLTQFGPLTPARAVAIVRQIAAALDAAHSNGVTHRDVK---------
MAV_4238|M.avium_104 LGSLLHREGPLAPPRAIAIIRQVAAALDAAHAAGVTHRDVT---------
TH_0100|M.thermoresistible__bu PDDWDDPVPGTGVGEFTAIADGLVRGFRGADRLYGYARHIV---------
Mvan_1720|M.vanbaalenii_PYR-1 VADEDAHSPAADALAVDAENTAPTAALRGQSSPGWFTGRVTGRVAASDVD
Mflv_2913|M.gilvum_PYR-GCK ESPLWLVAAAALRRQIDPATTYQATANSTSLTAEQADAIRRLG-------
MUL_0230|M.ulcerans_Agy99 -----LDEAFAVTAGGPAANRAYVSTVSTAYDA-----------------
MSMEG_4365|M.smegmatis_MC2_155 -----DEVAREITTGVTGIRTAIENAAPRIALPDLR--------------
Mb1006c|M.bovis_AF2122/97 -----------------------------------YAVAEAAS-------
Rv0980c|M.tuberculosis_H37Rv -----------------------------------YAVAEAAS-------
MMAR_4577|M.marinum_M -------------------PENILVADNDFAYLVDFGIARAAA-------
MAV_4238|M.avium_104 -------------------PGNILVTPSDFAYLADFGIARAAS-------
TH_0100|M.thermoresistible__bu -------------------ETTFLATSNGLRRRYTQPTGSVEINAKRDGA
Mvan_1720|M.vanbaalenii_PYR-1 GDRLSFTGMTTAKGTVTVTPWGTFTYRPSKAARHAAAATTASDAEKFDTF
Mflv_2913|M.gilvum_PYR-GCK -------------EILLDGPPTAMVATDTRAYLAHAGSKSITVIDTLKG-
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 -------------------PTTNLARPVTPVALKAAQPVQVSP-------
Mb1006c|M.bovis_AF2122/97 ------------ATPLQNVLDAINAPVQSLTGRPLIGDGANG--------
Rv0980c|M.tuberculosis_H37Rv ------------ATPLQNVLDAINAPVQSLTGRPLIGDGANG--------
MMAR_4577|M.marinum_M ------------DPGLTQGGMAVGTYNYMAPERFTGNDVTYR--------
MAV_4238|M.avium_104 ------------DPGLTQVGTAIGTYYYMAPERFTDDEVTNS--------
TH_0100|M.thermoresistible__bu SAWVGLNAPDFTAVTVDSMLEELSTRLGWARRRVELPAGRYETIMPPSTV
Mvan_1720|M.vanbaalenii_PYR-1 AITVSDGNGGWTEVPVTVAVRPVNSSPSWLRSTKTKPNPVSGEVNG-RII
Mflv_2913|M.gilvum_PYR-GCK ----------AVLQTISLRYTPTNLAVTPSGNRLYISNGIAG--------
MUL_0230|M.ulcerans_Agy99 ------------IAVIDVATNAVVSTHPLALSVSDLAASSDGK-------
MSMEG_4365|M.smegmatis_MC2_155 -----------PRPTITGLVRGLLTAAAGFSPRAATAPVAPAP-------
:
Mb1006c|M.bovis_AF2122/97 --------IDGTGQAGGNGGWLWGNGG-----------------------
Rv0980c|M.tuberculosis_H37Rv --------IDGTGQAGGNGGWLWGNGG-----------------------
MMAR_4577|M.marinum_M --------ADIYALACVLGECLTGAPP-----------------------
MAV_4238|M.avium_104 --------VDIYSLACVLTECLTGVPP-----------------------
TH_0100|M.thermoresistible__bu ADMLIYLNWHMDGRGAQEGRTALSAPG-----------------------
Mvan_1720|M.vanbaalenii_PYR-1 AIDRDGDAFTYTASAPGKGAVVVNLDGTFSYTASDSARAAARNTWYTDTD
Mflv_2913|M.gilvum_PYR-GCK ---------TVSVLNTATESVIKTIRVG----------------------
MUL_0230|M.ulcerans_Agy99 --------YVYASRNGARGADIAVLDT-----------------------
MSMEG_4365|M.smegmatis_MC2_155 ------SPAAWALLAFARREFERAFTPG----------------------
Mb1006c|M.bovis_AF2122/97 ----------NGGSGAP---------------------------GQAGGA
Rv0980c|M.tuberculosis_H37Rv ----------NGGSGAP---------------------------GQAGGA
MMAR_4577|M.marinum_M ----------YRADSVERLIAAHLMEPPPRPSQ----------LRPGRVP
MAV_4238|M.avium_104 ----------YRADTVERLVAAHLTKTAPPLSQ----------LRPGGFP
TH_0100|M.thermoresistible__bu ----------GGTRVGEKLTDLPLTMYSDPTADGLECLPFVAVPASSDRV
Mvan_1720|M.vanbaalenii_PYR-1 RFIVVVNDGHGGTRSVSVRVEVAPSNNAPTTGAPNLDAPDPGTGAVRGTV
Mflv_2913|M.gilvum_PYR-GCK -----------RTPTALAVNANGSRVYVVNSDDGTVSKISMLTNTVVGKV
MUL_0230|M.ulcerans_Agy99 ---------------------------------------------ATGRV
MSMEG_4365|M.smegmatis_MC2_155 ----------AATALAAPAITTSAVTSAAVVN------------PLPGRL
Mb1006c|M.bovis_AF2122/97 GGAAG-----------------LIGNGGAGG-------AGGQGLPFEAGA
Rv0980c|M.tuberculosis_H37Rv GGAAG-----------------LIGNGGAGG-------AGGQGLPFEAGA
MMAR_4577|M.marinum_M AALDE-----------------VIAKGMAKNPDERYMSAGDLAIAAHEAL
MAV_4238|M.avium_104 PALDR-----------------VIAKGMAKRPEDRYRTAGEFAAAAHEAL
TH_0100|M.thermoresistible__bu SVFDN-----------------GLAIGRVDWIRDGVINALAYPRAAAEEF
Mvan_1720|M.vanbaalenii_PYR-1 NAVDPDGDRITYRRETIMTAKGVLTIGSTGAFNYTPTTAARHAAATSDPN
Mflv_2913|M.gilvum_PYR-GCK YGVAEG--------------VSEITISPDGSTIYTLSSTTGQVSRFSSTA
MUL_0230|M.ulcerans_Agy99 DVVDI---------------------------------ATKPGLTTECVR
MSMEG_4365|M.smegmatis_MC2_155 DSVPVG---------------WVTGVSNPSGNWPQTNNTAGFDIWGTDLG
:
Mb1006c|M.bovis_AF2122/97 NGGA----------------------------------------------
Rv0980c|M.tuberculosis_H37Rv NGGA----------------------------------------------
MMAR_4577|M.marinum_M TTPE----------------------------------------------
MAV_4238|M.avium_104 TTSE----------------------------------------------
TH_0100|M.thermoresistible__bu HAPV----------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 LAADSVTITARDRFGGVGAIVLTIPIAPTNTSPVGSAAGAGVTDPVTGVV
Mflv_2913|M.gilvum_PYR-GCK LRAQ----------------------------------------------
MUL_0230|M.ulcerans_Agy99 VSAD----------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 IMWDG---------------------------------------------
Mb1006c|M.bovis_AF2122/97 -------GGAGGWLFGNGGAGGVGG-------------------------
Rv0980c|M.tuberculosis_H37Rv -------GGAGGWLFGNGGAGGVGG-------------------------
MMAR_4577|M.marinum_M -------QRQEATILRQGDNMALMTPAVDPGAGGSWTNYSGSGAQPPAPQ
MAV_4238|M.avium_104 -------QRKAATILRDGQIAALGAGAAEQRS----THWPDS--------
TH_0100|M.thermoresistible__bu -------AVPADNLLMTGGTASVRDMVARTERGLLLTTFWYIR-------
Mvan_1720|M.vanbaalenii_PYR-1 RGTVTATDSDGDDLLFSGTTTTEKGSVVVDSIGTYTYTPTTAARHHVNAE
Mflv_2913|M.gilvum_PYR-GCK -------QTVAVTPASQGITFSADGSRVFVADIAGSIRVLDAATGQQVDS
MUL_0230|M.ulcerans_Agy99 -----------GNRVDVGANGPSGGQLIVVAT------------------
MSMEG_4365|M.smegmatis_MC2_155 ------GEWNGQRFVHTAFGDTFSGPNMSGWWRSNVLLISTDN-------
.
Mb1006c|M.bovis_AF2122/97 ------------------------------------------------AG
Rv0980c|M.tuberculosis_H37Rv ------------------------------------------------AG
MMAR_4577|M.marinum_M PVAPPPQYPTGDETVARPVPASTTGWRSRPDVSDQRTQAAPVITGTSWPS
MAV_4238|M.avium_104 -FAPSP----SAETVVGPSPARAG------------------------AP
TH_0100|M.thermoresistible__bu -TVDPTTLLVTGLTRDGVYLVEDGEVTAAVNNFRFNESPLDVLRRATEAG
Mvan_1720|M.vanbaalenii_PYR-1 DATDADRRDSFVVTVTDGHGGTAQVLVSVAIAPSSNQAPGGVSYSANPNT
Mflv_2913|M.gilvum_PYR-GCK IAVTAGVPFDIAASPDGTTLYVAR-------------SEDGKLSAYDIAT
MUL_0230|M.ulcerans_Agy99 ------------------------------------------------HA
MSMEG_4365|M.smegmatis_MC2_155 ----------------------------------------------VLSD
Mb1006c|M.bovis_AF2122/97 GAGTTFGVAGGDGGTGG---------------------------------
Rv0980c|M.tuberculosis_H37Rv GAGTTFGVAGGDGGTGG---------------------------------
MMAR_4577|M.marinum_M QSGIRPAVGTGSSPSATPPASQP---------------------------
MAV_4238|M.avium_104 SSGLIRAAPTGSGRVYAPGPDFG---------------------------
TH_0100|M.thermoresistible__bu ASEYTLPREWGDWATRAKMPALXXXVRAAALVDILSGQEVSLFWSKNTIP
Mvan_1720|M.vanbaalenii_PYR-1 DTGVVEGRVTATDPEGDSLTFSGSAETGKGTVAVAPDGSFVYTPTDDARL
Mflv_2913|M.gilvum_PYR-GCK KTELTSVIANPYEVDGPPLISVS---------------------------
MUL_0230|M.ulcerans_Agy99 ESELNPVRGGRARSRGR---------------------------------
MSMEG_4365|M.smegmatis_MC2_155 GLGLVQTGTAYQFIPASGRNLFG---------------------------
Mb1006c|M.bovis_AF2122/97 ------------------------------------------VGGHGGLI
Rv0980c|M.tuberculosis_H37Rv ------------------------------------------VGGHGGLI
MMAR_4577|M.marinum_M -------------ATAPPASPKKSRKNWIIG--AAVVAVLLVVAGATAFV
MAV_4238|M.avium_104 -------------RPVAPTDNK--RKQWIIVGAVALVALVAFVVAVVGYL
TH_0100|M.thermoresistible__bu QRLWPSQGCPAGQRGLLSGLQRLDNVQPKPADGRTPHPMAAPMAGAHQQA
Mvan_1720|M.vanbaalenii_PYR-1 SAGAPGAPVASKEDSFVVDVSDGHGGTTSISVSVEIVPLIDNESPVAGTP
Mflv_2913|M.gilvum_PYR-GCK -----------------PDGTQLYWAEFGGTRVNVIALVPDNADPVAQAP
MUL_0230|M.ulcerans_Agy99 -----------------------------------------NGQGVAGSV
MSMEG_4365|M.smegmatis_MC2_155 -----------------------LFGGSEVTVIPTAGVQIDGTQYVNYMS
Mb1006c|M.bovis_AF2122/97 GVGGHGGDGGTGG-------------------------------------
Rv0980c|M.tuberculosis_H37Rv GVGGHGGDGGTGG-------------------------------------
MMAR_4577|M.marinum_M LAKPKG-STEPRGQVV----------------------------------
MAV_4238|M.avium_104 STASSGPAKQAGGQSV----------------------------------
TH_0100|M.thermoresistible__bu RYTPQNPPGAAPGWRL----------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 IVGDPTPGTGVVSGTLGFTDPEGSSLAYTVTGPPAKGLVSIDTTGGFTYT
Mflv_2913|M.gilvum_PYR-GCK VVNAPNTSGEVTGSVT----------------------------------
MUL_0230|M.ulcerans_Agy99 VQQFPRDLRIIDTIEIG---------------------------------
MSMEG_4365|M.smegmatis_MC2_155 VRSWDTPGRWTTNFSAIS--------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 PNPEDRPEAGEAPGYDAFTVVATDPQGLAAQVTVDVVVAPLLPPSDGPVV
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------TGGAVSLARAGTAGGAGGGP-AGG
Rv0980c|M.tuberculosis_H37Rv --------------------------TGGAVSLARAGTAGGAGGGP-AGG
MMAR_4577|M.marinum_M -----------------------LPFTGLNFRFAPGGVAVDANGTVYVTN
MAV_4238|M.avium_104 -----------------------LPFNGIDFRLSPGGVTLDGAGNVYVTS
TH_0100|M.thermoresistible__bu -----------------------DRITGPSRLFGANGLRTGPDGRVYIAQ
Mvan_1720|M.vanbaalenii_PYR-1 GTPPYDIDSVDEVTGVISGHVTAYTSNGTALTFAVAESPDVASGRVALDS
Mflv_2913|M.gilvum_PYR-GCK ----------------------VTDPEGRPLTYEVITTDKGSVTVTRGAD
MUL_0230|M.ulcerans_Agy99 -----------------------------SSVRDVAISPDGTTAYVASCG
MSMEG_4365|M.smegmatis_MC2_155 ----------------------VYDPSTDTWVLAPSTIRSAGWFRSSTLY
Mb1006c|M.bovis_AF2122/97 IGGTGGVGGAG-----------------------------------GAAG
Rv0980c|M.tuberculosis_H37Rv IGGAGGVGGAG-----------------------------------GAAG
MMAR_4577|M.marinum_M QTMYGRVVALP-----------------------------------AGSS
MAV_4238|M.avium_104 EGMYGRVVKLA-----------------------------------AGSG
TH_0100|M.thermoresistible__bu VTGS-QISALD-----------------------------------IATG
Mvan_1720|M.vanbaalenii_PYR-1 ATGRWTFTPTASTLVSAWSSDTPTPVTFTIRVSDGEKSTDITVSATVSPS
Mflv_2913|M.gilvum_PYR-GCK GAFAFTYKATS-----------------------------------AARH
MUL_0230|M.ulcerans_Agy99 ADFGAVIDVVD-----------------------------------TRTH
MSMEG_4365|M.smegmatis_MC2_155 VPGSQNFQQAA-----------------------------------YVLQ
Mb1006c|M.bovis_AF2122/97 AVTTITHAS--FNDPHGVAVNPGGNIYVTNQGSNTVSVIDPV--------
Rv0980c|M.tuberculosis_H37Rv AVTTITHAS--FNDPHGVAVNPGGNIYVTNQGSNTVSVIDPV--------
MMAR_4577|M.marinum_M TPTVKPFNG--LYEPQGVAVDTSGKIYVTDFNNRVVALAAGS--------
MAV_4238|M.avium_104 ATTVLPFNG--LYQPQGLAVDGAGTVYVADFNNRVLSMAAGS--------
TH_0100|M.thermoresistible__bu ALETISPKGGDIISPDDVAFDPHGNLVATEVMEGRVSLRDTAGRARVLRD
Mvan_1720|M.vanbaalenii_PYR-1 EQAVINSVEYLGSEPSGVTVGPDGRMYVIDSGANTLSIINPADASMITVT
Mflv_2913|M.gilvum_PYR-GCK EAAADDAAPETKQDTFVLTFTDGQRGVVSVPITVTIPPANAAPTATVR--
MUL_0230|M.ulcerans_Agy99 KITGTRKIEEIGGLITRLSIGGNGERAYLVSEDRVTVLSARS--------
MSMEG_4365|M.smegmatis_MC2_155 PEDQVGEDGIRYLYAFGTPSGRAGSAYLSRVPEDAVTDLSKYEYWD----
.
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu DIPSANGITFHRG-------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VGKNPTSVASDDLGRLWVTNSGDHTVTVLNAEAEILRTVQVGLVPASVVI
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 ---------------------TNTVTGSITDGNGPSGVAVSPVTGLVFVT
Rv0980c|M.tuberculosis_H37Rv ---------------------TNTVTGSITDGNGPSGVAVSPVTGLVFVT
MMAR_4577|M.marinum_M ---------------------NNQVELPFNGLNYPEGIAVDAQGNVYVAD
MAV_4238|M.avium_104 ---------------------NSQKELPFSGLNYPEGVAVDSQGGVYVAD
TH_0100|M.thermoresistible__bu --RLFIGECREGGRLLEFSLNGDAPRVLLDNVPSPNAMEVGPDGLLYFPV
Mvan_1720|M.vanbaalenii_PYR-1 RGDLAYIANFGGNSLSVIDAADDYSVRSVDVGTNPIDIAIGSDGRIYVAN
Mflv_2913|M.gilvum_PYR-GCK ---------------------SSVSWLSAKVLGTITARDADRDTLTYLAS
MUL_0230|M.ulcerans_Agy99 ----------------------QDVIGTVRVNQPSAAIESPGGDRLYVAD
MSMEG_4365|M.smegmatis_MC2_155 ---------------------GNRWVTGNAAVAAPVIGDSTRSTGLFGFI
.
Mb1006c|M.bovis_AF2122/97 NFDSNTVSVIDPNTNTVTGSIPVGT-GAYGVAVNPGGNIYVTNQFSNTVS
Rv0980c|M.tuberculosis_H37Rv NFDSNTVSVIDPNTNTVTGSIPVGT-GAYGVAVNPGGNIYVTNQFSNTVS
MMAR_4577|M.marinum_M RGNNRVVKMPAGSTSQVVLPFNGLK-NPDGVAVDSDGNVYVTDTDNNRVL
MAV_4238|M.avium_104 RGNSRVLKLAAGSQNQTVLPFTGLN-NPDGVAVDPAGNVYVADTDNNRVV
TH_0100|M.thermoresistible__bu MGANEIWRIDPDQPGAAPQTVATGLGVPDAVKFDPAGHIVSTQVATGQVL
Mvan_1720|M.vanbaalenii_PYR-1 FGNGTISVLRPDDMDDVLLVDSGGE-HPHGILVDDDGTVYVTHPLDDTVT
Mflv_2913|M.gilvum_PYR-GCK PTAKGGTVTIGNDGRFTYTPTAAAR------HAAANANATEADKQDTFDV
MUL_0230|M.ulcerans_Agy99 YSGTVTMTLVDLGVSAIDNALCQGL---------------SADWVMPELL
MSMEG_4365|M.smegmatis_MC2_155 VDWANDPNVLGGYLGGLVGAKTGGN--------VSELSVQYNEYLGKYVV
.
Mb1006c|M.bovis_AF2122/97 VIDPATNTVTGSP-------------------------------------
Rv0980c|M.tuberculosis_H37Rv VIDPATNTVTGSP-------------------------------------
MMAR_4577|M.marinum_M QLDAGTSNQSVLP-------------------------------------
MAV_4238|M.avium_104 KLDAASNTQSELP-------------------------------------
TH_0100|M.thermoresistible__bu RIDPRTGEQTVLATLTPGLDNLTFVGDRLFVSNFTGEITEILGDGSTRAT
Mvan_1720|M.vanbaalenii_PYR-1 VLNPAPVNRFSLRSLFSADATSGQYTYRSVTVIG------------APTK
Mflv_2913|M.gilvum_PYR-GCK VINDGHGGLTTLT-------------------------------------
MUL_0230|M.ulcerans_Agy99 QFEAALA-------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 LYGDGNNNIQMR--------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu LPGGLNWPLDLAVGADGALYVADGTYFYAVRPDGSLQTVGMLFSSGYPGF
Mvan_1720|M.vanbaalenii_PYR-1 ITKDTAGRIYVTNSSGATITVLDPLTLAANEIHTGANPSSVYVDRFGNLY
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu IRGVEPSGPGEFVVTTSGGQVTRYRPADSESEVLADGLDQLYGLALAGDG
Mvan_1720|M.vanbaalenii_PYR-1 VTNAGQKTVAVIHAQTRNITTYRADVKTSQVTTDDDGNLVMVSTYDGHRS
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 -----------------------IPVGLDPTGVAVNPVTGVVYVTNS---
Rv0980c|M.tuberculosis_H37Rv -----------------------IPVGLDPTGVAVNPVTGVVYVTNS---
MMAR_4577|M.marinum_M -----------------------FSNLTAPWGITVDSAGNVYVTEHD---
MAV_4238|M.avium_104 -----------------------FHDLSVPWGIAVDNGGTVYVTEHD---
TH_0100|M.thermoresistible__bu TVVCAEQGTGRLLAVRGGEVEVLATGLTQPVGVALDPDGTPLVAESG---
Mvan_1720|M.vanbaalenii_PYR-1 VLSTDTVSTGADALQIANVWGSYGSLVASPDGKWLYAVRNRRVDTTGGLY
Mflv_2913|M.gilvum_PYR-GCK -----------------------VTVTVKPGNDAPDARVRTTASWFG---
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 -------------------------IADRPEGPWSDPIELASSADYPG--
Mb1006c|M.bovis_AF2122/97 --LDDTVSVITG--------------------------------------
Rv0980c|M.tuberculosis_H37Rv --LDDTVSVITG--------------------------------------
MMAR_4577|M.marinum_M --NNAVAKLAAG--------------------------------------
MAV_4238|M.avium_104 --KNDVVKYPPG--------------------------------------
TH_0100|M.thermoresistible__bu --AGRIVRVAGGRTDTVVDQLSCPQGILVRGNQLYIVDATAKELLAVDLA
Mvan_1720|M.vanbaalenii_PYR-1 PNRYDIVAIDTSNNSVRTFAWDAHINGSMVLTMNRDGDRLYAAYYTLDPE
Mflv_2913|M.gilvum_PYR-GCK ---PEVYGTVVAR-------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 -LYAPMIHPWSG--------------------------------------
Mb1006c|M.bovis_AF2122/97 ---------------------EPARSVCSAAI------------------
Rv0980c|M.tuberculosis_H37Rv ---------------------EPARSVCSAAI------------------
MMAR_4577|M.marinum_M ---------------------ATTSTELPFTGLNTPLS-VAVDKK-----
MAV_4238|M.avium_104 ---------------------ATSGTVLPFTALNTPLA-VAVDRD-----
TH_0100|M.thermoresistible__bu TGQRQRIATGLPVGSPPGVQPKPLKGMPPFSGPQGPFAGITAGPD-----
Mvan_1720|M.vanbaalenii_PYR-1 VFDGVVAKVAIINVDGSTLQLDGAPVELNLGSTTAFVSDIVVNPAGTKVF
Mflv_2913|M.gilvum_PYR-GCK ---------------------DQDRDGLTFTASDTAKGGVIVMDSR----
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 ------------------------TGMLEDDNGDPDVNNLYWNMS-----
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M ----------------------GNVYVADRGNGRVLKLAQGS--------
MAV_4238|M.avium_104 ----------------------QSVYVADRGDDRVVKLAQ----------
TH_0100|M.thermoresistible__bu ----------------------GTLYLSADGDGSVLALRRTR--------
Mvan_1720|M.vanbaalenii_PYR-1 VIGDRLAVPGQWDAPEGQWNMYGNLWMVDLENDRAVSRPPIPRPLQAEGG
Mflv_2913|M.gilvum_PYR-GCK ----------------------GRFTYTPAEAARHAAAAAEATAADKQ--
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------LWGDYNVVLMQTDLSGLKTVAV--------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VPDLAISPDGRYAYLVMTPLPGWEGNHYLGIFDTQSFALTTVLLGHFEAP
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------DTFDIT
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 NGVRRLVVSPDGTRIYLSDGQIVGVTGTQHELLEDRIQGIDQERFVDIAI
Mflv_2913|M.gilvum_PYR-GCK VDDGHGGVTTVAVTVRIKPVNAAPRGASAAELFANPNSGLTTGKITAVDA
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 NPEGTRLYTTTWDGVLTTIDTSTGLPVGNPTDLGNRAWGMTFGPKGDTLY
Mflv_2913|M.gilvum_PYR-GCK DGDSLTYRVSPSTGRGIVDVATDGTFTYRPTEAAREAASRPFAPSWVR--
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VRRGVDYVASHRAPQSIADLWENVRDLPNGDNEGIFTQVVRHADGTNRMV
Mflv_2913|M.gilvum_PYR-GCK --------------------------------TDRFRVTVDDGHGGTTTL
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VYLGGTNPRNWLVGEQAIGENVVSELGILKDEHLGAITRALAHCRNDATC
Mflv_2913|M.gilvum_PYR-GCK TVRVPIAPTGYVNQAPTDGKYTAGQPNPSSGKVSGTVTAADP--------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 GDIADVMLVGFSQGGIDGQNFASQWDRLGFGVQLSALVTFGSPITKNPNV
Mflv_2913|M.gilvum_PYR-GCK -ERDDIYYLGSGQTAKGGTVVVERDGRFVYTPTDAARQQAASPDASDEDR
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 PTLHIQDIDDEVVNTELLARLAATVQYVPMPSWLRINFAAATVTAMARGQ
Mflv_2913|M.gilvum_PYR-GCK QDSFVVTAIDQYAATLAVPVTVSILPWAASIAGLV---------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 --------------------------------------------------
Rv0980c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4577|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 LYQGAADTDISVLDIFAVHGNRATYQQLASEMDARTGTDFAALGPVRTFF
Mflv_2913|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0230|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
Mb1006c|M.bovis_AF2122/97 -------------
Rv0980c|M.tuberculosis_H37Rv -------------
MMAR_4577|M.marinum_M -------------
MAV_4238|M.avium_104 -------------
TH_0100|M.thermoresistible__bu -------------
Mvan_1720|M.vanbaalenii_PYR-1 GGTALIPGDPTPL
Mflv_2913|M.gilvum_PYR-GCK -------------
MUL_0230|M.ulcerans_Agy99 -------------
MSMEG_4365|M.smegmatis_MC2_155 -------------