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PMVNVGIGLQALGHDICVLTGAEFSDAVHAAGLQMIPLPDSVRIDPPAAAPALLRKLPVAVRRFWLGRAE LASVFAEPLAAEAQSLRAVLRNGSVDAIVADVAFTGVLPVLLQDSPRPPVVVCGVGPLTISSRDTPPFGV AWQPERGLDYRRMTTAAHRVIMRSSQRRFNHALRQAGSDACPLFVSDWPRLADGLLQLSVQALEYPRGDL PATVEFVGPVLPAGPEDFDPPHWWGDVMNAGAVVHVTQGTFDNADLDQLIAPTLEALGDRADLLVVATTG GRQGQRIHGRIPANARIADWIPYSALLPHVDVMITNGGYGGVQHALAHGVPLVVAGETSDKAEVAARVDY SGVGIDLKTATPTPEAIRAAVDHVRRDGRYRSAAERLRSAIEASTPVDAIANAIKRLCNA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4886 | - | - | 100% (411) | UDP-glucuronosyl/UDP-glucosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4034 | - | 3e-83 | 44.28% (411) | glycosyl transferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4035 | - | 3e-79 | 43.20% (419) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2986c | - | 7e-22 | 34.51% (226) | glycosyl transferase |
| M. gilvum PYR-GCK | Mflv_1849 | - | 1e-169 | 70.63% (412) | UDP-glucuronosyl/UDP-glucosyltransferase |
| M. tuberculosis H37Rv | Rv2962c | - | 7e-22 | 34.51% (226) | glycosyl transferase |
| M. leprae Br4923 | MLBr_00125 | - | 1e-21 | 33.33% (228) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_3062c | - | 4e-14 | 27.29% (414) | hypothetical protein MAB_3062c |
| M. marinum M | MMAR_1755 | - | 1e-16 | 29.32% (249) | glycosyl transferase |
| M. avium 104 | MAV_3631 | - | 2e-12 | 25.55% (411) | hypothetical protein MAV_3631 |
| M. smegmatis MC2 155 | MSMEG_4670 | - | 4e-80 | 43.07% (397) | N-glycosylation |
| M. thermoresistible (build 8) | TH_3465 | - | 1e-143 | 60.00% (410) | PUTATIVE UDP-glucuronosyl/UDP-glucosyltransferase |
| M. ulcerans Agy99 | MUL_3383 | - | 4e-14 | 27.93% (401) | glycosyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4886|M.vanbaalenii_PYR-1 -----------------------------------------MPMVNVGIG
Mflv_1849|M.gilvum_PYR-GCK -----------------------------------------MPMVDVGAG
TH_3465|M.thermoresistible__bu --VGGYGLTRTRLLGRRLSSGSEDEFLARYLLAATPLSGHVAPLVQIGAT
MSMEG_4670|M.smegmatis_MC2_155 --------------------------MADILIASHSPIGHIGPLLNVAYG
MAV_3631|M.avium_104 ---------------------------MRVAVVAGPDPGHSFPAIALCRR
MUL_3383|M.ulcerans_Agy99 ---------------------------MRVAVVAGPDPGHSFPAIALCRR
MAB_3062c|M.abscessus_ATCC_199 ---------------------------MRVAVVAGPDPGHAFPALALCLK
Mb2986c|M.bovis_AF2122/97 MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE
Rv2962c|M.tuberculosis_H37Rv MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE
MMAR_1755|M.marinum_M -------------------------MSIATN---AP-QPVRRQRVLFVAE
MLBr_00125|M.leprae_Br4923 ---------------------MGKDAGMSTAPDTVPECQSRRMRILFIAE
: .
Mvan_4886|M.vanbaalenii_PYR-1 LQALGHDICVLTGAEFSDAVHAAGLQMIPLPDSVRIDPPAAAPALLRKLP
Mflv_1849|M.gilvum_PYR-GCK LQSLGHEVTILTAAEYADLVEAAGLQMLCLPGSVVIDPPAAAPVVMRRMP
TH_3465|M.thermoresistible__bu LRSRGHTVTVLTTTEFADAVTRAGLRFTALPAGTAIDPPAAPPWWARYLP
MSMEG_4670|M.smegmatis_MC2_155 LVGRGDRVTVLTSAQHTDAIRASGAAPVALPDAG--DPDADRLDIENPKR
MAV_3631|M.avium_104 FADAGDTPTLFTGAEWLDTARGAGVDAVELDGLAA--TDEDVDAGARIHR
MUL_3383|M.ulcerans_Agy99 FLAAGDIPTLLTGVEWLDTARAAGVDAIELAGLVA--TDEDLDAGARIHR
MAB_3062c|M.abscessus_ATCC_199 FAAAGDDPVLLTGTRWLDQARAAGVESVELLGLQPRVDDDDADSGAKIHQ
Mb2986c|M.bovis_AF2122/97 AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP
Rv2962c|M.tuberculosis_H37Rv AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP
MMAR_1755|M.marinum_M ATTLAHVVRPFVVALSLDPSRYEVHFACDPRFNKLLGPIPFPHHPIYTIP
MLBr_00125|M.leprae_Br4923 AVTLAHVVRPFAVARLLDPSRYEVHFACDPRYNNLLGPLPFPHHPIHTVP
.. :. . *
Mvan_4886|M.vanbaalenii_PYR-1 VAVRRFWLGRAELASVFAEPLAAEAQSLRAVLRNGSVDAIVADVAFTGVL
Mflv_1849|M.gilvum_PYR-GCK PAVRRFWLGRAELDAIFAKPLAAEAESLTSALAATTYDAVVADVTFTGVL
TH_3465|M.thermoresistible__bu SQARRFLLGRAELDSVYIRPLGHQAAALRSVLDREPADAVLVDMTFTGAA
MSMEG_4670|M.smegmatis_MC2_155 ARTSGIARINVDIVAFFVAPMAHQADALAKLLAQHRFDAVIADYGFFGIL
MAV_3631|M.avium_104 RAARMAVLNVPALRDLAPDLVVSDVITAGGGMAAELLG------------
MUL_3383|M.ulcerans_Agy99 RAAQMALLNAPALSDLAPDLVVSDVITACGGMAAERLG------------
MAB_3062c|M.abscessus_ATCC_199 RAAHMALANLDQLRALAPDLIVSDVITACGGMAGELLG------------
Mb2986c|M.bovis_AF2122/97 SERFFGNLTQGR--FYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSV
Rv2962c|M.tuberculosis_H37Rv SERFFGNLTQGR--FYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSV
MMAR_1755|M.marinum_M SERFLGNLVQGR--FYTTRTLRQYVEEDSRVLAEVAPDLVVGDLRISLSA
MLBr_00125|M.leprae_Br4923 SKRFLDNMAQGRLFLYGPRTLRKYVEEDSKLLSEIEPDLVVGDLRWSLSV
: . : .
Mvan_4886|M.vanbaalenii_PYR-1 PVLLQDSP-RPPVVVCGVGPLTISSRDTPPFGVAWQPE----RGLDYRRM
Mflv_1849|M.gilvum_PYR-GCK PMLLRDDA-RPPVVVCGVGPLTISSTDTPPFGMAWQPE----AGVDYTQM
TH_3465|M.thermoresistible__bu ALLLDDRP-RPPLLVCSVGPLTLSSADTPPFGMAWQPR----PGVDYRGM
MSMEG_4670|M.smegmatis_MC2_155 PFLLGNRADRPPFLTYSTTPLMLSSRDTAPAGLGLPPPRHAVERLRNRAL
MAV_3631|M.avium_104 ----------IPWIELSPHPLYLPSKGLPPIGSGLATG----TGLRGR--
MUL_3383|M.ulcerans_Agy99 ----------IPWIELNPHPLYRPSKGLPPIGSGLAPG----TGIRGR--
MAB_3062c|M.abscessus_ATCC_199 ----------VPWVELNPHPLYLPSKGLPPLGSGLAPG----VGLRGR--
Mb2986c|M.bovis_AF2122/97 SARLAG----IPYIAIANAYWSPYAQRRFPLPDVIWTR---LFGVRLVKL
Rv2962c|M.tuberculosis_H37Rv SARLAG----IPYIAIANAYWSPYAQRRFPLPDVIWTR---LFGVRLVKL
MMAR_1755|M.marinum_M SARLAG----IPYVAIANAYWSPYSRRRFPLPEVFWSR---LFGVRLVKR
MLBr_00125|M.leprae_Br4923 SARLAS----IPYIAIANAYWSSHARRRFPLPDVLYTH---LLGVRLVKL
* : : * . :
Mvan_4886|M.vanbaalenii_PYR-1 TT-AAHRVIMRSSQRRFNHALRQAGSDACPLFVSDWPRLADGLLQLSVQA
Mflv_1849|M.gilvum_PYR-GCK TA-VAHRVIMRASQRRFDRALRRAGCGRSPVFISDWPRLADGILQLSVRD
TH_3465|M.thermoresistible__bu TA-VAHRVIMAGSRRRFDRALRTAGAGPAPVFLSDWPALADRLIQLGVPG
MSMEG_4670|M.smegmatis_MC2_155 ET-LTHKVLLRASQRAVQEQLHRMNCRPLPVFLFDGAVLSERVIAPTVPQ
MAV_3631|M.avium_104 ---LRDATMRALTARSWRAGLRQRAAARAEIGLPARDPGPLRRLIATLPA
MUL_3383|M.ulcerans_Agy99 ---LRDTTMRALTARSWRAGLRQRAAVRAEIGLAEHDPGPLRRLIATLPA
MAB_3062c|M.abscessus_ATCC_199 ---LRDGLMRRLTQKSIDQGLRQRSQARVEIGLPARDPGPMRRLIATLPA
Mb2986c|M.bovis_AF2122/97 LYRLERPLLFALQCMPLNWVRRRHGLSSLGWNLCRIFTDGDHTLYADVPE
Rv2962c|M.tuberculosis_H37Rv LYRLERPLLFALQCMPLNWVRRRHGLSSLGWNLCRIFTDGDHTLYADVPE
MMAR_1755|M.marinum_M AYRLERPLFFALQCMPLNRVRRKHGLPSLGLNLCRIFTDGDQTLYADIPE
MLBr_00125|M.leprae_Br4923 LYRLERPLFFAFQCLPLNWVRRKHGLPSLGFNLCRIFTDGDYTLYADVPE
: : : : :
Mvan_4886|M.vanbaalenii_PYR-1 LEYPRGDLPATVEFVGPVLPAGPEDFDPPHWWGDVMNAG-AVVHVTQGTF
Mflv_1849|M.gilvum_PYR-GCK FEYPRSDLPATVEYVGPVLPDGTAGFVPPPWWREIERDGTTVVHVTQGTF
TH_3465|M.thermoresistible__bu FEYHRGDLPSTVDFAGPVLPTGLDGVTLPAWWDDIRSAA-TVVHVTQGTF
MSMEG_4670|M.smegmatis_MC2_155 FDYHRSDLPKNVRYVGAVHPMPNQGFRRPMWWRLLDGDR-PVVHVTQGTV
MAV_3631|M.avium_104 LEVPRPDWPDEAVLVGPLHFEPTDRVLD-------IPAGSGPVVVVAPST
MUL_3383|M.ulcerans_Agy99 LEVPRPDWPAEAIVVGPLHFEPTDQLLK-------VPAGSGPVLVIAPST
MAB_3062c|M.abscessus_ATCC_199 LEVPRPDWPAEAVVVGPLHWEPTDVVLQ-------PPSGSGPVVVIAPST
Mb2986c|M.bovis_AF2122/97 LMP-TYDLPANHEYLGPVLWSPAGKPPT------WWDSLPTDRPIVYATL
Rv2962c|M.tuberculosis_H37Rv LMP-TYDLPANHEYLGPVLWSPAGKPPT------WWDSLPTDRPIVYATL
MMAR_1755|M.marinum_M LQP-TYNRPDNHQYLGPVLWSPSGETPD------WWDSLPADRPIVYATL
MLBr_00125|M.leprae_Br4923 LVP-TYDLPANHQYLGPVLWSPAGELPR------WWDSLPTDRPIVYATL
: : * *.: : :
Mvan_4886|M.vanbaalenii_PYR-1 DNADLDQLIAPTLEALGDRADLLVVATTGGRQGQRIHGRIPANARIADWI
Mflv_1849|M.gilvum_PYR-GCK DNTDLNQLIGPTFEALEDLDDVLVVATTGGRAGQRIADRIPSNVLVAEWI
TH_3465|M.thermoresistible__bu DNTDLDQLVVPTLEALTDRPDVLVVATTGGRPGQRSGFRVPGNARVTGWL
MSMEG_4670|M.smegmatis_MC2_155 DNTDLTRLLEPTLEALAD-EDVVVIASTGGRDLDVLRTPVPANTYVAKYI
MAV_3631|M.avium_104 AQTGARGLAEVALSCLTPGETLPAGARLVVSRLAGPELAAPP-WAVVGLG
MUL_3383|M.ulcerans_Agy99 ALSGTAGLAEVALESLIPGGTLSSGSRLVVSRLGGDDLVTPS-WAAVGLG
MAB_3062c|M.abscessus_ATCC_199 AFTGAEGMTELAVQALES-----AGARVVISALEPPSSGLPS-WAIAGLA
Mb2986c|M.bovis_AF2122/97 GTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKT----VPANAFVADYL
Rv2962c|M.tuberculosis_H37Rv GTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKT----VPANAFVADYL
MMAR_1755|M.marinum_M GTSGGRNLLQVVLNGLADLPVTVIAATADRSDLDD----IPANAYVADYL
MLBr_00125|M.leprae_Br4923 GTSGGKNLLQVVLDALADLPVTVIAATAGRSELQN----VPANAFVADYL
:. : ... * : * .
Mvan_4886|M.vanbaalenii_PYR-1 PYSALLPHVDVMITNGGYGGVQHALAHGVPLVVAGETSDKAEVAARVDYS
Mflv_1849|M.gilvum_PYR-GCK PYSALLPNVDVMITNGGYGGVQYALGHGVPLIVAGETSDKAEVAARVAYT
TH_3465|M.thermoresistible__bu PYRMLMPHVDVMITNGGYGGVQYALSHGVPLIVAGETSDKAEIAARVEFC
MSMEG_4670|M.smegmatis_MC2_155 PHDLLMPKVDVLVTNGGYGTVQRALSCGVPLVVAGKTEDKPEVAARVAWS
MAV_3631|M.avium_104 SQAELLRHADVVVCGGGHGMVAKTLLAGVPLVAVPGGGDQWEIANRVVRQ
MUL_3383|M.ulcerans_Agy99 SQAELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGGGDQWEIANRVVRQ
MAB_3062c|M.abscessus_ATCC_199 RQDLLLSGADLAVCGGGHGFLSKALLAGVPTVVVPGGGDQWELANRVVRQ
Mb2986c|M.bovis_AF2122/97 PGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERA
Rv2962c|M.tuberculosis_H37Rv PGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERA
MMAR_1755|M.marinum_M PGEAAAARSDVVICNGGSLTTQQALVAGVPVLGIASNLDQHLNMQAIEAA
MLBr_00125|M.leprae_Br4923 PGEAAAARSAVVICNGGSLTTQQAFVAGVPVVGIAGNLDQHLNMEAVEAA
: : .** :: *** : *: :
Mvan_4886|M.vanbaalenii_PYR-1 GVGIDLKTATPTPEAIRAAVDHVRRDGRYRSAAERLRSAIEA-STPVDAI
Mflv_1849|M.gilvum_PYR-GCK GVGIDLGTSSPSAAAIRAAVDAVRRDDRYREAAGKLRTVIEA-STPIDAI
TH_3465|M.thermoresistible__bu GAGIDLGTATPTVRALRAGFDRIRDQDRYRTAARRLAREIRS-AAPLDSI
MSMEG_4670|M.smegmatis_MC2_155 GAGIDLRTGTPTPAAIRDAVREVLTDKRYLSRARTLEAAFAQ-RDGVAEI
MAV_3631|M.avium_104 GSARLIRPLS--ADALVAAVNEVLSSPGYRAAAQRAAAGIAD-VADPVRV
MUL_3383|M.ulcerans_Agy99 GSARLIRPLG--ADALAAAVNEVLSSPGYREAAQRAAASIAD-VADPVQV
MAB_3062c|M.abscessus_ATCC_199 GSAELVRPLS--RDSLASAIGRVLGEPRYREAARRAAAGAIA-VEDPVRV
Mb2986c|M.bovis_AF2122/97 GAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAARLADAFGRDRVGFPQH
Rv2962c|M.tuberculosis_H37Rv GAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAARLADAFGRDRVGFPQH
MMAR_1755|M.marinum_M GAGLLLRTERLKARSVSAAVCQLLDRPGYRQSAEELAEVFGRELARFPQH
MLBr_00125|M.leprae_Br4923 GAGILLRSERLKVRRVADAVNRVLGQSEYRQAAQRLAEVLERHVAGLPQH
* . : . : .. : * *
Mvan_4886|M.vanbaalenii_PYR-1 ANAIKRLCNA----------------------------------
Mflv_1849|M.gilvum_PYR-GCK ASVLKRCADA----------------------------------
TH_3465|M.thermoresistible__bu AATLERIVAADALNRSARTGSAGAPDPDSTDDRPAPRPARPRVH
MSMEG_4670|M.smegmatis_MC2_155 IALVDEVIAERRAEVGGELACEVTHEQR----------------
MAV_3631|M.avium_104 CREALAG-------------------------------------
MUL_3383|M.ulcerans_Agy99 CHEALALAG-----------------------------------
MAB_3062c|M.abscessus_ATCC_199 CQDVLAALR-----------------------------------
Mb2986c|M.bovis_AF2122/97 VENALRLMPENRPRTWLAS-------------------------
Rv2962c|M.tuberculosis_H37Rv VENALRLMPENRPRTWLAS-------------------------
MMAR_1755|M.marinum_M VESALRRVSEGAVAKSAAG-------------------------
MLBr_00125|M.leprae_Br4923 MENVLHTVSQNPPPTSLARQKRPLRFG-----------------