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VGKDAGMSTAPDTVPECQSRRMRILFIAEAVTLAHVVRPFAVARLLDPSRYEVHFACDPRYNNLLGPLPF PHHPIHTVPSKRFLDNMAQGRLFLYGPRTLRKYVEEDSKLLSEIEPDLVVGDLRWSLSVSARLASIPYIA IANAYWSSHARRRFPLPDVLYTHLLGVRLVKLLYRLERPLFFAFQCLPLNWVRRKHGLPSLGFNLCRIFT DGDYTLYADVPELVPTYDLPANHQYLGPVLWSPAGELPRWWDSLPTDRPIVYATLGTSGGKNLLQVVLDA LADLPVTVIAATAGRSELQNVPANAFVADYLPGEAAAARSAVVICNGGSLTTQQAFVAGVPVVGIAGNLD QHLNMEAVEAAGAGILLRSERLKVRRVADAVNRVLGQSEYRQAAQRLAEVLERHVAGLPQHMENVLHTVS QNPPPTSLARQKRPLRFG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_00125 | - | - | 100% (438) | putative glycosyl transferase |
M. leprae Br4923 | MLBr_00128 | - | 0.0 | 93.27% (431) | putative glycosyl transferase |
M. leprae Br4923 | MLBr_00985 | - | 8e-10 | 31.77% (192) | putative glycosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2986c | - | 0.0 | 77.46% (426) | glycosyl transferase |
M. gilvum PYR-GCK | Mflv_2592 | - | 1e-23 | 35.05% (214) | glycosyl transferase family protein |
M. tuberculosis H37Rv | Rv2962c | - | 0.0 | 77.46% (426) | glycosyl transferase |
M. abscessus ATCC 19977 | MAB_3062c | - | 2e-09 | 28.49% (186) | hypothetical protein MAB_3062c |
M. marinum M | MMAR_1755 | - | 1e-179 | 74.39% (410) | glycosyl transferase |
M. avium 104 | MAV_3631 | - | 6e-09 | 31.61% (193) | hypothetical protein MAV_3631 |
M. smegmatis MC2 155 | MSMEG_4670 | - | 2e-21 | 39.11% (179) | N-glycosylation |
M. thermoresistible (build 8) | TH_3465 | - | 1e-19 | 38.25% (183) | PUTATIVE UDP-glucuronosyl/UDP-glucosyltransferase |
M. ulcerans Agy99 | MUL_3383 | - | 5e-09 | 30.21% (192) | glycosyl transferase |
M. vanbaalenii PYR-1 | Mvan_4034 | - | 2e-21 | 35.10% (208) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2592|M.gilvum_PYR-GCK ---------------------------------------MNAMPDILITA Mvan_4034|M.vanbaalenii_PYR-1 ------------------------------------------MPEILIAT MSMEG_4670|M.smegmatis_MC2_155 ------------------------------------------MADILIAS TH_3465|M.thermoresistible__bu ------------------VGGYGLTRTRLLGRRLSSGSEDEFLARYLLAA MAV_3631|M.avium_104 -------------------------------------------MRVAVVA MUL_3383|M.ulcerans_Agy99 -------------------------------------------MRVAVVA MAB_3062c|M.abscessus_ATCC_199 -------------------------------------------MRVAVVA Mb2986c|M.bovis_AF2122/97 MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE Rv2962c|M.tuberculosis_H37Rv MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE MMAR_1755|M.marinum_M -------------------------MSIATN---AP-QPVRRQRVLFVAE MLBr_00125|M.leprae_Br4923 ---------------------MGKDAGMSTAPDTVPECQSRRMRILFIAE :. Mflv_2592|M.gilvum_PYR-GCK CPPVGHIGPLLNVAHGLVAHGHRVTVLTSARHADKIRAVGADPRPLPYGA Mvan_4034|M.vanbaalenii_PYR-1 CPPVGHLSPLLNVARGLVARGDRVTVLTSARHADKIRAVGAEPRPLPHAA MSMEG_4670|M.smegmatis_MC2_155 HSPIGHIGPLLNVAYGLVGRGDRVTVLTSAQHTDAIRASGAAPVALPDAG TH_3465|M.thermoresistible__bu TPLSGHVAPLVQIGATLRSRGHTVTVLTTTEFADAVTRAGLRFTALPAGT MAV_3631|M.avium_104 GPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLDTARGAGVDAVELDGLA MUL_3383|M.ulcerans_Agy99 GPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAAGVDAIELAGLV MAB_3062c|M.abscessus_ATCC_199 GPDPGHAFPALALCLKFAAAGDDPVLLTGTRWLDQARAAGVESVELLGLQ Mb2986c|M.bovis_AF2122/97 AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP Rv2962c|M.tuberculosis_H37Rv AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP MMAR_1755|M.marinum_M ATTLAHVVRPFVVALSLDPSRYEVHFACDPRFNKLLGPIPFPHHPIYTIP MLBr_00125|M.leprae_Br4923 AVTLAHVVRPFAVARLLDPSRYEVHFACDPRYNNLLGPLPFPHHPIHTVP .* . : : . . . : Mflv_2592|M.gilvum_PYR-GCK DYD----DARLDADLPGRAHTSGIARINFDVEHVFVRPMPYQFSAVQELL Mvan_4034|M.vanbaalenii_PYR-1 DYD----DSTLDADLPGRAATAGLARINFDIESIFVRPLPHQFSALQELL MSMEG_4670|M.smegmatis_MC2_155 DPD----ADRLDIENPKRARTSGIARINVDIVAFFVAPMAHQADALAKLL TH_3465|M.thermoresistible__bu AIDPPAAPPWWARYLPSQARRFLLGRA--ELDSVYIRPLGHQAAALRSVL MAV_3631|M.avium_104 A-----------------------TDEDVDAGARIHRRAARMAVLNVPAL MUL_3383|M.ulcerans_Agy99 A-----------------------TDEDLDAGARIHRRAAQMALLNAPAL MAB_3062c|M.abscessus_ATCC_199 PRV---------------------DDDDADSGAKIHQRAAHMALANLDQL Mb2986c|M.bovis_AF2122/97 SER------------------FFGNLTQGR--FYAMRTLRKYVEADLRVL Rv2962c|M.tuberculosis_H37Rv SER------------------FFGNLTQGR--FYAMRTLRKYVEADLRVL MMAR_1755|M.marinum_M SER------------------FLGNLVQGR--FYTTRTLRQYVEEDSRVL MLBr_00125|M.leprae_Br4923 SKR------------------FLDNMAQGRLFLYGPRTLRKYVEEDSKLL * Mflv_2592|M.gilvum_PYR-GCK AANSFDAVITDAFFLGVIPLLLDPTLARPPIMAYSTTPLFLSSRDTAPAG Mvan_4034|M.vanbaalenii_PYR-1 VTDRFDAVIADALFLGTLPLLLGDPAKRPPILSYSTTPLFLTSRDTAPAG MSMEG_4670|M.smegmatis_MC2_155 AQHRFDAVIADYGFFGILPFLLGNRADRPPFLTYSTTPLMLSSRDTAPAG TH_3465|M.thermoresistible__bu DREPADAVLVDMTFTGAAALLLDDRP-RPPLLVCSVGPLTLSSADTPPFG MAV_3631|M.avium_104 RDLAPDLVVSDVITAGGG---MAAELLGIPWIELSPHPLYLPSKGLPPIG MUL_3383|M.ulcerans_Agy99 SDLAPDLVVSDVITACGG---MAAERLGIPWIELNPHPLYRPSKGLPPIG MAB_3062c|M.abscessus_ATCC_199 RALAPDLIVSDVITACGG---MAGELLGVPWVELNPHPLYLPSKGLPPLG Mb2986c|M.bovis_AF2122/97 DEIAPDLVVGDLRISLSVS----ARLAGIPYIAIAN--AYWSPYAQRRFP Rv2962c|M.tuberculosis_H37Rv DEIAPDLVVGDLRISLSVS----ARLAGIPYIAIAN--AYWSPYAQRRFP MMAR_1755|M.marinum_M AEVAPDLVVGDLRISLSAS----ARLAGIPYVAIAN--AYWSPYSRRRFP MLBr_00125|M.leprae_Br4923 SEIEPDLVVGDLRWSLSVS----ARLASIPYIAIAN--AYWSSHARRRFP * :: * * : .. Mflv_2592|M.gilvum_PYR-GCK PGILPMPGAVGRLRNRLLGLLSRAVLLRPAHRSAERMLRAMGLPDLPVFV Mvan_4034|M.vanbaalenii_PYR-1 PGIAPMPGMIGRLRNRVLARATQSVLLRPGQRAADRMLEAMGLPELPVFI MSMEG_4670|M.smegmatis_MC2_155 LGLPPPRHAVERLRNRALETLTHKVLLRASQRAVQEQLHRMNCRPLPVFL TH_3465|M.thermoresistible__bu MAWQPRPG----VDYRGMTAVAHRVIMAGSRRRFDRALRTAGAGPAPVFL MAV_3631|M.avium_104 SGLATGTGLRGRLRDATMRALTARSWRAG--------LRQRAAARAEIGL MUL_3383|M.ulcerans_Agy99 SGLAPGTGIRGRLRDTTMRALTARSWRAG--------LRQRAAVRAEIGL MAB_3062c|M.abscessus_ATCC_199 SGLAPGVGLRGRLRDGLMRRLTQKSIDQG--------LRQRSQARVEIGL Mb2986c|M.bovis_AF2122/97 LPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNL Rv2962c|M.tuberculosis_H37Rv LPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNL MMAR_1755|M.marinum_M LPEVFWSRLFGVRLVKRAYRLERPLFFALQCMPLNRVRRKHGLPSLGLNL MLBr_00125|M.leprae_Br4923 LPDVLYTHLLGVRLVKLLYRLERPLFFAFQCLPLNWVRRKHGLPSLGFNL . : Mflv_2592|M.gilvum_PYR-GCK LECAILADRVIVPTVPDFEYPRRDLPAHVRFVGAVSPLPGDDFIAPAWWG Mvan_4034|M.vanbaalenii_PYR-1 LDSAVLADRVIVPTVPEFEYRRSDLPSHVRFVGPVSPLPGSDFVAPPWWG MSMEG_4670|M.smegmatis_MC2_155 FDGAVLSERVIAPTVPQFDYHRSDLPKNVRYVGAVHPMPNQGFRRPMWWR TH_3465|M.thermoresistible__bu SDWPALADRLIQLGVPGFEYHRGDLPSTVDFAGPVLPTGLDGVTLPAWWD MAV_3631|M.avium_104 PARDPGPLRRLIATLPALEVPRPDWPDEAVLVGPLHFEPTDRVLD----- MUL_3383|M.ulcerans_Agy99 AEHDPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFEPTDQLLK----- MAB_3062c|M.abscessus_ATCC_199 PARDPGPMRRLIATLPALEVPRPDWPAEAVVVGPLHWEPTDVVLQ----- Mb2986c|M.bovis_AF2122/97 CRIFTDGDHTLYADVPELMP-TYDLPANHEYLGPVLWSPAGKPPT--WWD Rv2962c|M.tuberculosis_H37Rv CRIFTDGDHTLYADVPELMP-TYDLPANHEYLGPVLWSPAGKPPT--WWD MMAR_1755|M.marinum_M CRIFTDGDQTLYADIPELQP-TYNRPDNHQYLGPVLWSPSGETPD--WWD MLBr_00125|M.leprae_Br4923 CRIFTDGDYTLYADVPELVP-TYDLPANHQYLGPVLWSPAGELPR--WWD : :* : : * *.: Mflv_2592|M.gilvum_PYR-GCK ELYRGRPVVHVTQGTVDNADLTRLIEPTIEALAG-EDVTVVVSTGGRPVS Mvan_4034|M.vanbaalenii_PYR-1 ELNAGRPVVHVTQGTIDNADLTRLIEPTIEALAD-EDVTVVATTGGRPIS MSMEG_4670|M.smegmatis_MC2_155 LLDGDRPVVHVTQGTVDNTDLTRLLEPTLEALAD-EDVVVIASTGGRDLD TH_3465|M.thermoresistible__bu DIRSAATVVHVTQGTFDNTDLDQLVVPTLEALTDRPDVLVVATTGGRPGQ MAV_3631|M.avium_104 -IPAGSGPVVVVAPSTAQTGARGLAEVALSCLTPGETLPAGARLVVSRLA MUL_3383|M.ulcerans_Agy99 -VPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGGTLSSGSRLVVSRLG MAB_3062c|M.abscessus_ATCC_199 -PPSGSGPVVVIAPSTAFTGAEGMTELAVQALES-----AGARVVISALE Mb2986c|M.bovis_AF2122/97 SLPTDRPIVYATLG---TSGGRNLLQLVLNALAELPVTVIAATAGRSDLK Rv2962c|M.tuberculosis_H37Rv SLPTDRPIVYATLG---TSGGRNLLQLVLNALAELPVTVIAATAGRSDLK MMAR_1755|M.marinum_M SLPADRPIVYATLG---TSGGRNLLQVVLNGLADLPVTVIAATADRSDLD MLBr_00125|M.leprae_Br4923 SLPTDRPIVYATLG---TSGGKNLLQVVLDALADLPVTVIAATAGRSELQ * . :. : .:. * Mflv_2592|M.gilvum_PYR-GCK QIRTPLPANTFVAEFLPHDVLLPLVDVLVTNGGYGAVQRALAEGVPLVVA Mvan_4034|M.vanbaalenii_PYR-1 QIRIPLPANTFVAKYVPHDVLLPMVDVMVTNGGYGAVQRALSDGVPVVVA MSMEG_4670|M.smegmatis_MC2_155 VLRTPVPANTYVAKYIPHDLLMPKVDVLVTNGGYGTVQRALSCGVPLVVA TH_3465|M.thermoresistible__bu RSGFRVPGNARVTGWLPYRMLMPHVDVMITNGGYGGVQYALSHGVPLIVA MAV_3631|M.avium_104 GPELAAPP-WAVVGLGSQAELLRHADVVVCGGGHGMVAKTLLAGVPLVAV MUL_3383|M.ulcerans_Agy99 GDDLVTPS-WAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVVV MAB_3062c|M.abscessus_ATCC_199 PPSSGLPS-WAIAGLARQDLLLSGADLAVCGGGHGFLSKALLAGVPTVVV Mb2986c|M.bovis_AF2122/97 T----VPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGV Rv2962c|M.tuberculosis_H37Rv T----VPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGV MMAR_1755|M.marinum_M D----IPANAYVADYLPGEAAAARSDVVICNGGSLTTQQALVAGVPVLGI MLBr_00125|M.leprae_Br4923 N----VPANAFVADYLPGEAAAARSAVVICNGGSLTTQQAFVAGVPVVGI * . : : .** :: *** : Mflv_2592|M.gilvum_PYR-GCK GDTEDKPEVAARVEYFGVGVNLRTGTPAPQDLRDAVNAVLSDAGYRTRAG Mvan_4034|M.vanbaalenii_PYR-1 GHTEDKPEVAARVRHFGVGIDLRTGTPTPTQVRRAVRKVLHEPGFRTKAG MSMEG_4670|M.smegmatis_MC2_155 GKTEDKPEVAARVAWSGAGIDLRTGTPTPAAIRDAVREVLTDKRYLSRAR TH_3465|M.thermoresistible__bu GETSDKAEIAARVEFCGAGIDLGTATPTVRALRAGFDRIRDQDRYRTAAR MAV_3631|M.avium_104 PGGGDQWEIANRVVRQGSARLIRP--LSADALVAAVNEVLSSPGYRAAAQ MUL_3383|M.ulcerans_Agy99 PGGGDQWEIANRVVRQGSARLIRP--LGADALAAAVNEVLSSPGYREAAQ MAB_3062c|M.abscessus_ATCC_199 PGGGDQWELANRVVRQGSAELVRP--LSRDSLASAIGRVLGEPRYREAAR Mb2986c|M.bovis_AF2122/97 AGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAA Rv2962c|M.tuberculosis_H37Rv AGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAA MMAR_1755|M.marinum_M ASNLDQHLNMQAIEAAGAGLLLRTERLKARSVSAAVCQLLDRPGYRQSAE MLBr_00125|M.leprae_Br4923 AGNLDQHLNMEAVEAAGAGILLRSERLKVRRVADAVNRVLGQSEYRQAAQ *: : * . : . : .. : : * Mflv_2592|M.gilvum_PYR-GCK RLQAAYASRDSVTAIAALLDEVIPEQAAAR-------------------- Mvan_4034|M.vanbaalenii_PYR-1 WLRSAYAAYDSVAEIAKLVDEAVAQRTQPLQSA----------------- MSMEG_4670|M.smegmatis_MC2_155 TLEAAFAQRDGVAEIIALVDEVIAERRAEVGGELACEVTHEQR------- TH_3465|M.thermoresistible__bu RLAREIRSAAPLDSIAATLERIVAADALNRSARTGSAGAPDPDSTDDRPA MAV_3631|M.avium_104 RAAAGIAD---VADPVRVCREALAG------------------------- MUL_3383|M.ulcerans_Agy99 RAAASIAD---VADPVQVCHEALALAG----------------------- MAB_3062c|M.abscessus_ATCC_199 RAAAGAIA---VEDPVRVCQDVLAALR----------------------- Mb2986c|M.bovis_AF2122/97 RLADAFGRD--RVGFPQHVENALRLMPENRPRTWLAS------------- Rv2962c|M.tuberculosis_H37Rv RLADAFGRD--RVGFPQHVENALRLMPENRPRTWLAS------------- MMAR_1755|M.marinum_M ELAEVFGRE--LARFPQHVESALRRVSEGAVAKSAAG------------- MLBr_00125|M.leprae_Br4923 RLAEVLERH--VAGLPQHMENVLHTVSQNPPPTSLARQKRPLRFG----- : Mflv_2592|M.gilvum_PYR-GCK --------- Mvan_4034|M.vanbaalenii_PYR-1 --------- MSMEG_4670|M.smegmatis_MC2_155 --------- TH_3465|M.thermoresistible__bu PRPARPRVH MAV_3631|M.avium_104 --------- MUL_3383|M.ulcerans_Agy99 --------- MAB_3062c|M.abscessus_ATCC_199 --------- Mb2986c|M.bovis_AF2122/97 --------- Rv2962c|M.tuberculosis_H37Rv --------- MMAR_1755|M.marinum_M --------- MLBr_00125|M.leprae_Br4923 ---------