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MTGSPLTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGSRWNAAAISGEYLSAASFLGVAGLIAK YGADALWYPVGFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSPRLRKVAMLVVVVICIFYLVPQYQG AGLALKTLLGVPVWLGPLAVGAIVIMNVVAGGMRSITFVQAFQYWLKLTAVAIPALALAGLFLTDRGGEL GGPLPPTVQQITTVEIETDVVVQVAEPAGITVTGTLDDRQVDGAKIGPAGDHTLGAGSTLTLSAGAATPV VAGTPSAGRDWISSGGGLGGRHPLYQVLSIMVATFLGTMGLPHVLVRFYTNPDGRAARRTALAVIALLSL FYLFPTLLGVFSRLYVPQLLITGTADAAVLLAPGSVIAGVAGQLLAALVAAGAIAAFLATSSGLLVSFAG ALATDVLPGRVRDFRVAAVIGGLIPIPLALAASGELELSRSVGLAFAVAASTLCPLLVLGIWWRGLTATG AMAGLAVGGVLSGGAVTVAVAGGIDENVLGGWPTVLVGYPAAVSVPLAFATMLAVSRLTRATAPPDVAQT FARMHLPEHLGMGIERMPRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4562 | - | - | 100% (580) | Na+/solute symporter |
| M. vanbaalenii PYR-1 | Mvan_4564 | - | 6e-54 | 29.92% (595) | SSS family solute/sodium (Na+) symporter |
| M. vanbaalenii PYR-1 | Mvan_0815 | - | 2e-15 | 25.31% (557) | Na+/solute symporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2141 | - | 0.0 | 92.41% (580) | Na+/solute symporter |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4639 | - | 8e-07 | 22.58% (217) | putative Na+/solute symporter |
| M. marinum M | MMAR_4287 | - | 0.0001 | 26.04% (338) | PE-PGRS family protein |
| M. avium 104 | MAV_4700 | - | 2e-06 | 27.95% (347) | DipZ protein |
| M. smegmatis MC2 155 | MSMEG_5161 | - | 0.0 | 84.85% (581) | transmembrane transport protein |
| M. thermoresistible (build 8) | TH_3825 | - | 4e-12 | 23.58% (530) | PUTATIVE putative Na+/solute symporter |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4562|M.vanbaalenii_PYR-1 ------MTGSPLTAAALLAAAVATIAIGAYGVRFSRTTSDFLVA-----S
Mflv_2141|M.gilvum_PYR-GCK ------MTGSPLTAVALLAAAVATVAIGAYGVRFSRTTSDFLVA-----S
MSMEG_5161|M.smegmatis_MC2_155 ------MTGSPLTAAALLFAAVATIAIGAYGVKFSRTTSDFLVA-----S
TH_3825|M.thermoresistible__bu ----------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVA-----G
MAB_4639|M.abscessus_ATCC_1997 MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVSSSIDFFLS-----G
MMAR_4287|M.marinum_M --MSFVFAEPQYLSAAATDLASIGSTIDTAGSAAALATTGVIPAGLDEVS
MAV_4700|M.avium_104 ---MQTIALIGFLGGLITGISPCILPVLPVILLSGMDGDRRGVG------
.
Mvan_4562|M.vanbaalenii_PYR-1 RTVGSRWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLG
Mflv_2141|M.gilvum_PYR-GCK RTVGSRWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLG
MSMEG_5161|M.smegmatis_MC2_155 RSVGSRWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLG
TH_3825|M.thermoresistible__bu RALPAVLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLL
MAB_4639|M.abscessus_ATCC_1997 RSLPAWVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILF
MMAR_4287|M.marinum_M AGIAALFGAHGQAYQELSARAALFHDEFVRVLSAGADAYASSEVANAQAV
MAV_4700|M.avium_104 -SAARPYLVIAGLVCSFSVATLIGSALLTALHLPQDAIRWTALVVLTAIG
.. : .
Mvan_4562|M.vanbaalenii_PYR-1 LLLFV---AAPLRRSGAYTVPDFAEFRLGSPRLRKVAMLVVVVICIFYLV
Mflv_2141|M.gilvum_PYR-GCK LLLFV---AAPLRRSGAYTVPDFAEFRLGSTRLRKVAMLVVVVICIFYLV
MSMEG_5161|M.smegmatis_MC2_155 LLLFV---AAPLRRSGAYTVPDFAEFRLGSVWLRKVAMLVVVVICVFYLA
TH_3825|M.thermoresistible__bu MGLFF---ARRLRAAQVVTLPEYFGNRFGRG-VEVASSALTVGSFAILLA
MAB_4639|M.abscessus_ATCC_1997 LGIVM---MPFFYGSQVRSVPEYMLHRFGVG-AHLVNATGFAVAQVLIAG
MMAR_4287|M.marinum_M LAAGP---GGLFEQVGRVQAGFTANLVSGELAFNQALVANEAAVIDAVGG
MAV_4700|M.avium_104 LGLIFPPLQQLIERPFAYLPQRQSRPGADGFGLGLTLGALYVPCAGPVLA
: : . . .
Mvan_4562|M.vanbaalenii_PYR-1 PQYQGAGLALKTLLGVPVWLG---------------PLAVGAIVIMNVVA
Mflv_2141|M.gilvum_PYR-GCK PQYQGAGLALKTLLGTPVWLG---------------PLAVGAIVIMNVVA
MSMEG_5161|M.smegmatis_MC2_155 PQYQGAGLALKTLLGAPVWIG---------------PLLVGAIVITNVVA
TH_3825|M.thermoresistible__bu GNLVAIGFLLERFLGVSYTIG---------------ILVTVPLALLYTIT
MAB_4639|M.abscessus_ATCC_1997 VNLYLLGTIVNVLLGWPLWVS---------------VIAAAAIVLCYITL
MMAR_4287|M.marinum_M ANSLVGGVIYGGFNATNLVVGTGQQFVNTLVGAQIPASLSTSLLLGGQVP
MAV_4700|M.avium_104 AIVVAGGTSSIGPGALVLTAT---------------FAAGNALPLLAFAL
* . .: :
Mvan_4562|M.vanbaalenii_PYR-1 GGMRSITFVQAFQYWLKLTAVAIPALALAGLFLTDRGGELGGPLPPTVQQ
Mflv_2141|M.gilvum_PYR-GCK GGMRSITFVQAFQYWLKLTAVAIPALALAGLFLSDRGGDLGGPLPPTVHQ
MSMEG_5161|M.smegmatis_MC2_155 GGMRSITFVQAFQYWLKLTAIAIPALALLGLFINDRG-ELGGPLPPSVEE
TH_3825|M.thermoresistible__bu GGMFASVYTGVAQVVVNIVGVFA---------------------------
MAB_4639|M.abscessus_ATCC_1997 GGLSAAIYNEVLQFFVIVAALLP---------------------------
MMAR_4287|M.marinum_M GAQIGAGLSGVVQTGQSLAGSFNAALSGMG---TQLSAALSGSLSAGLPD
MAV_4700|M.avium_104 AGRRVAQRVAAFRRRQRAIQVAGG--------------------IAMIVL
.. . :
Mvan_4562|M.vanbaalenii_PYR-1 ITTVEIETDVVVQVAEPAGITVTGTLDDRQVDGAKIGPAGDHTLGAGSTL
Mflv_2141|M.gilvum_PYR-GCK ETTVQIETDVVVQVAEPAGITVTGTLDNRDVEGVPIGSAGRHTLGAGSSL
MSMEG_5161|M.smegmatis_MC2_155 QTTVAIDTDVVVRVVEPAGITVTGTLDGQEVADAPIGAPGDHTLDAGTTL
TH_3825|M.thermoresistible__bu ---------LVVWVAATHGFTAP------------------DGMGAGALS
MAB_4639|M.abscessus_ATCC_1997 --------LTIVGLHQVGGWQGLQ-----------------DKVSAGQMS
MMAR_4287|M.marinum_M LSSLGVQLGAGLSGDLSAGLPSVSGLVQTGQVLAGSFNDAVGGLGSRVAG
MAV_4700|M.avium_104 AVALVFNLPAMLQRAVPDYTTAMQNRLGANDLQRSLSPPGPPPTQGGALQ
: .
Mvan_4562|M.vanbaalenii_PYR-1 TLSAGAATPVVAGTPSAGRDWISSGGGLGGRHPLYQVLSIMVATFLGTMG
Mflv_2141|M.gilvum_PYR-GCK TLAAGAATPVVDGTPSAGADWISSGGGLGGQHPLYQVLSIMVATFLGTMG
MSMEG_5161|M.smegmatis_MC2_155 TLDAGAATPVVAGTPSTGSQWLASGGGLGGGHPLYQVVSIIVATFLGTMG
TH_3825|M.thermoresistible__bu QLTSSESGAVIN-------------------------WATIIALGLGNLV
MAB_4639|M.abscessus_ATCC_1997 SWPGNELSGFSDNLLSVIG--------------IVFGLGFVLSFGYWTTN
MMAR_4287|M.marinum_M VLSGAVGGELPDLSGLVQAGAVLMGGVGTALSGLGAQLSAALSGSLG-TA
MAV_4700|M.avium_104 LSPGDVTGGGALSDCSDGLAELQRCGPAPALTGITGWLNTPDGKPLDPAA
. .
Mvan_4562|M.vanbaalenii_PYR-1 LPHVLVRFYTNPDGRAARRTALAVIALLS--------------LFYLFPT
Mflv_2141|M.gilvum_PYR-GCK LPHVLVRFYTNPDGRAARRTALAVIALLS--------------LFYLFPT
MSMEG_5161|M.smegmatis_MC2_155 LPHVLVRFYTNPDGRAARRTALAVIALLS--------------LFYLFPT
TH_3825|M.thermoresistible__bu AIDLMQRVFSARDPGAAQRACFAAAGGIL--------------LLCLPLS
MAB_4639|M.abscessus_ATCC_1997 FVEVQRALASESLSAARRTPIIGAFPKMF--------------IPFIVVI
MMAR_4287|M.marinum_M VPGLSALIQTGESLAGGFNAALGTLGTQVSGMLSGGLGGGLPGLAALIQT
MAV_4700|M.avium_104 VRGKVILIDFWAYSCINCQRAIPHVIDWY---------------DRYHDS
. :
Mvan_4562|M.vanbaalenii_PYR-1 ---LLGVFSR---------LYVPQLLITGTADAAVLLAP--GSVIAGVAG
Mflv_2141|M.gilvum_PYR-GCK ---LLGVFSR---------WYVPQLLITGTADAAVLLAP--GSAIGGAAG
MSMEG_5161|M.smegmatis_MC2_155 ---LLGVFSR---------LYVPQLLITGTADAAVLLAP--GAAIGGALG
TH_3825|M.thermoresistible__bu ---FVALAAV---------GIVG----DSAGDGPILYA-----LLGEYAP
MAB_4639|M.abscessus_ATCC_1997 PGMICAVLVP---------QMVAYKAGQPTSDPNLTYSNSLLYLMKEVLP
MMAR_4287|M.marinum_M GESLAGGFGTGLTGFMGGVDVLGNLGGELSAVGAQFNAAVAAGLTGDFSG
MAV_4700|M.avium_104 GFLVIGVHTP--------EYAFERVPGNVASGAADLHIGYPIALDNDYAT
. . . :.
Mvan_4562|M.vanbaalenii_PYR-1 QLLAALVAAGAIAAFLATS----SGLLVSFAG---ALATDVLPGRV----
Mflv_2141|M.gilvum_PYR-GCK QLLAALVAAGAIAAFLATS----SGLLVSFAG---ALATDVLPGRV----
MSMEG_5161|M.smegmatis_MC2_155 QLLAALVAAGAIAAFLATS----SGLLVSIAG---ALATDVLRGRV----
TH_3825|M.thermoresistible__bu AWLAIIVISGLLAATLTTV----SGILLSTAS---VLVRNVLR-------
MAB_4639|M.abscessus_ATCC_1997 NGVLGVAITGLLASFMAGM----AANVSAFNT---VFSYDLWQRYIRKDR
MMAR_4287|M.marinum_M FPVLVDTVSGLPGAVLAQLGQAQNGVLAGFVDGQLAFNQSLVANEVALQQ
MAV_4700|M.avium_104 WNNYQNLYWPAEYLIDATG----QVRHTKFGEGDYDGTERLIR-------
: :
Mvan_4562|M.vanbaalenii_PYR-1 --------------------------RDFRVAAVIGGLIPIPLA--LAAS
Mflv_2141|M.gilvum_PYR-GCK --------------------------RDFRVAAVVGGLIPIPLA--LAAS
MSMEG_5161|M.smegmatis_MC2_155 --------------------------RDFRVAAVIGGIIPIPLS--LFVS
TH_3825|M.thermoresistible__bu --------------------------IDTGVLAPPAAMTPRMLR--ATRW
MAB_4639|M.abscessus_ATCC_1997 PDG---------------------YYLRIGRIATVGATVIAIGT--AFIA
MMAR_4287|M.marinum_M ALFGTDAALNGAVNHGFNAVNLLVGTGEQAVNAVLGAPTPASFTGSLLVG
MAV_4700|M.avium_104 ---------------------------ELLAAAHPGARLPAPAN---TAD
* ..
Mvan_4562|M.vanbaalenii_PYR-1 GELELSRSVG-LAFAVAASTLCPLLVLGIWWRGLTATGAMAGLAVGGVLS
Mflv_2141|M.gilvum_PYR-GCK GDLELSRSVG-LAFAVAASTLCPLLVLGIWWRGLTARGAMSGLAVGGLLS
MSMEG_5161|M.smegmatis_MC2_155 G-LELSRSVG-LAFAVAASTLCPLLVLGIWWRRLTVVGAASGLVVGGVVC
TH_3825|M.thermoresistible__bu ATLPMAALAAVVALRVPQTGILLTLAFDLLLASLVVPFILGLYWSRGGAA
MAB_4639|M.abscessus_ATCC_1997 ANYNNVMNYLQTLFAFFNAPLFATFILGMFWRRMTATAGWAGLVSGTFAA
MMAR_4287|M.marinum_M GSLEGDIPTGGLPGVAHQLLLLNAALGGPALVDASWLSQFGQAQAAFNAD
MAV_4700|M.avium_104 TTPQSRLTPETYLGVGKAGNYGGTGDYRSGTATLSYPATLGEDRFALRGR
.
Mvan_4562|M.vanbaalenii_PYR-1 G-------GAVTVAVAGGIDENVLGGWPTVLVGYPAAVSVP---------
Mflv_2141|M.gilvum_PYR-GCK G-------GAVTVAVAGGIDENALGGWPAVLIGYPAALSVP---------
MSMEG_5161|M.smegmatis_MC2_155 G-------SAVIIAIAGGVDENVLGGWPAVMIGYPAAVSVP---------
TH_3825|M.thermoresistible__bu A-------AAAAVVVGIGVRLTYFVLAPTIYGVDNTLLYLP---------
MAB_4639|M.abscessus_ATCC_1997 VGIWSLFETGVYTLAGQGSNFIEAGVAFTVDIVVSVAVSWT---------
MMAR_4287|M.marinum_M VLSGQLAFNESLVTNEMALQQAIFGTDSALNGAVNHAFNMVNFTLGAGQQ
MAV_4700|M.avium_104 WTLDD--QGATAAGDDCAVRLNYTAKDVYAVVGGTGTLTVTR--------
. .
Mvan_4562|M.vanbaalenii_PYR-1 -LAFATMLAVSRLTRATAP-PDVAQTFARMHLPEHLGMGIERMPRA----
Mflv_2141|M.gilvum_PYR-GCK -LAFATMILVSRFTRDEVP-PDVAQTFARMHVPENLGMGIERLPRA----
MSMEG_5161|M.smegmatis_MC2_155 -LAFLTMIVVSLATRTTLSGPTVAQIFARMHVPERLGMGVERLPQSR---
TH_3825|M.thermoresistible__bu -NDWVSAXXRGGGPSGVRD--TPSDTPREMHPRNALA-------------
MAB_4639|M.abscessus_ATCC_1997 -TEPKPAAELAGLVYSETPHAFSSDEPASGWFRQPVKLAMTALILVVALN
MMAR_4287|M.marinum_M TVDALLGVPVPADFTGSLLASGSADAFGGVTTGGLLGAVEQKFLMDGAFL
MAV_4700|M.avium_104 -DGTTTTTPIGGAPTLHRIVADDSAHRDQLDMRVSPGLQVFSFTFG----
:
Mvan_4562|M.vanbaalenii_PYR-1 ------------------------------------------
Mflv_2141|M.gilvum_PYR-GCK ------------------------------------------
MSMEG_5161|M.smegmatis_MC2_155 ------------------------------------------
TH_3825|M.thermoresistible__bu ------------------------------------------
MAB_4639|M.abscessus_ATCC_1997 LIFH--------------------------------------
MMAR_4287|M.marinum_M SVFGVPIQVTLDGRLPELIGQLTGSASGGVEVGTEVGGEIPE
MAV_4700|M.avium_104 ------------------------------------------