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M. smegmatis MC2 155 MSMEG_5161 (-)

MTGSPLTAAALLFAAVATIAIGAYGVKFSRTTSDFLVASRSVGSRWNAAAISGEYLSAASFLGVAGLIAK
YGADALWYPVGFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSVWLRKVAMLVVVVICVFYLAPQYQG
AGLALKTLLGAPVWIGPLLVGAIVITNVVAGGMRSITFVQAFQYWLKLTAIAIPALALLGLFINDRGELG
GPLPPSVEEQTTVAIDTDVVVRVVEPAGITVTGTLDGQEVADAPIGAPGDHTLDAGTTLTLDAGAATPVV
AGTPSTGSQWLASGGGLGGGHPLYQVVSIIVATFLGTMGLPHVLVRFYTNPDGRAARRTALAVIALLSLF
YLFPTLLGVFSRLYVPQLLITGTADAAVLLAPGAAIGGALGQLLAALVAAGAIAAFLATSSGLLVSIAGA
LATDVLRGRVRDFRVAAVIGGIIPIPLSLFVSGLELSRSVGLAFAVAASTLCPLLVLGIWWRRLTVVGAA
SGLVVGGVVCGSAVIIAIAGGVDENVLGGWPAVMIGYPAAVSVPLAFLTMIVVSLATRTTLSGPTVAQIF
ARMHVPERLGMGVERLPQSR

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_5161	-	-	100% (580)	transmembrane transport protein
M. smegmatis MC2 155	MSMEG_5166	-	5e-55	30.58% (582)	Na+/solute symporter
M. smegmatis MC2 155	MSMEG_5303	putP	2e-21	24.14% (526)	sodium/proline symporter

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_2141	-	0.0	84.17% (581)	Na+/solute symporter
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_4639	-	8e-07	22.75% (211)	putative Na+/solute symporter
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. thermoresistible (build 8)	TH_3825	-	2e-12	22.87% (529)	PUTATIVE putative Na+/solute symporter
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4562	-	0.0	84.85% (581)	Na+/solute symporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2141|M.gilvum_PYR-GCK          ------MTGSPLTAVALLAAAVATVAIGAYGVRFSRTTSDFLVASRTVGS
Mvan_4562|M.vanbaalenii_PYR-1       ------MTGSPLTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGS
MSMEG_5161|M.smegmatis_MC2_155      ------MTGSPLTAAALLFAAVATIAIGAYGVKFSRTTSDFLVASRSVGS
TH_3825|M.thermoresistible__bu      ----------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGRALPA
MAB_4639|M.abscessus_ATCC_1997      MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVSSSIDFFLSGRSLPA
                                               :         * .:.    . :      :::::.*:: :

Mflv_2141|M.gilvum_PYR-GCK          RWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLGLLLFV
Mvan_4562|M.vanbaalenii_PYR-1       RWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLGLLLFV
MSMEG_5161|M.smegmatis_MC2_155      RWNAAAISGEYLSAASFLGVAGLIAKYGADA-LWYPVGFTAGYLGLLLFV
TH_3825|M.thermoresistible__bu      VLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLMGLFF
MAB_4639|M.abscessus_ATCC_1997      WVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILFLGIVM
                                       . .: .  :.:   :* :   * :*  .     :* .   * : :..

Mflv_2141|M.gilvum_PYR-GCK          AAPLRRSGAYTVPDFAEFRLGSTRLRKVAMLVVVVICIFYLVPQYQGAGL
Mvan_4562|M.vanbaalenii_PYR-1       AAPLRRSGAYTVPDFAEFRLGSPRLRKVAMLVVVVICIFYLVPQYQGAGL
MSMEG_5161|M.smegmatis_MC2_155      AAPLRRSGAYTVPDFAEFRLGSVWLRKVAMLVVVVICVFYLAPQYQGAGL
TH_3825|M.thermoresistible__bu      ARRLRAAQVVTLPEYFGNRFGRG-VEVASSALTVGSFAILLAGNLVAIGF
MAB_4639|M.abscessus_ATCC_1997      MPFFYGSQVRSVPEYMLHRFGVG-AHLVNATGFAVAQVLIAGVNLYLLGT
                                       :  : . ::*::   *:*    . .     .    :    :    * 

Mflv_2141|M.gilvum_PYR-GCK          ALKTLLGTPVWLGPLAVGAIVIMNVVAGGMRSITFVQAFQYWLKLTAVAI
Mvan_4562|M.vanbaalenii_PYR-1       ALKTLLGVPVWLGPLAVGAIVIMNVVAGGMRSITFVQAFQYWLKLTAVAI
MSMEG_5161|M.smegmatis_MC2_155      ALKTLLGAPVWIGPLLVGAIVITNVVAGGMRSITFVQAFQYWLKLTAIAI
TH_3825|M.thermoresistible__bu      LLERFLGVSYTIGILVTVPLALLYTITGGMFASVYTGVAQVVVNIVGVFA
MAB_4639|M.abscessus_ATCC_1997      IVNVLLGWPLWVSVIAAAAIVLCYITLGGLSAAIYNEVLQFFVIVAALLP
                                     :: :** .  :. : . .:.:     **: :  :  . *  : :..:  

Mflv_2141|M.gilvum_PYR-GCK          PALALAGLFLSDRGGDLGGPLPPTVHQETTVQIETDVVVQVAEPAGITVT
Mvan_4562|M.vanbaalenii_PYR-1       PALALAGLFLTDRGGELGGPLPPTVQQITTVEIETDVVVQVAEPAGITVT
MSMEG_5161|M.smegmatis_MC2_155      PALALLGLFINDRG-ELGGPLPPSVEEQTTVAIDTDVVVRVVEPAGITVT
TH_3825|M.thermoresistible__bu      ------------------------------------LVVWVAATHGFTAP
MAB_4639|M.abscessus_ATCC_1997      -----------------------------------LTIVGLHQVGGWQGL
                                                                         :* :    *    

Mflv_2141|M.gilvum_PYR-GCK          GTLDNRDVEGVPIGSAGRHTLGAGSSLTLAAGAATPVVDGTPSAGADWIS
Mvan_4562|M.vanbaalenii_PYR-1       GTLDDRQVDGAKIGPAGDHTLGAGSTLTLSAGAATPVVAGTPSAGRDWIS
MSMEG_5161|M.smegmatis_MC2_155      GTLDGQEVADAPIGAPGDHTLDAGTTLTLDAGAATPVVAGTPSTGSQWLA
TH_3825|M.thermoresistible__bu      ------------------DGMGAGALSQLTSSESGAVIN-----------
MAB_4639|M.abscessus_ATCC_1997      Q-----------------DKVSAGQMSSWPGNELSGFSDNLLSVIG----
                                                      . :.**      ..    .             

Mflv_2141|M.gilvum_PYR-GCK          SGGGLGGQHPLYQVLSIMVATFLGTMGLPHVLVRFYTNPDGRAARRTALA
Mvan_4562|M.vanbaalenii_PYR-1       SGGGLGGRHPLYQVLSIMVATFLGTMGLPHVLVRFYTNPDGRAARRTALA
MSMEG_5161|M.smegmatis_MC2_155      SGGGLGGGHPLYQVVSIIVATFLGTMGLPHVLVRFYTNPDGRAARRTALA
TH_3825|M.thermoresistible__bu      --------------WATIIALGLGNLVAIDLMQRVFSARDPGAAQRACFA
MAB_4639|M.abscessus_ATCC_1997      ----------IVFGLGFVLSFGYWTTNFVEVQRALASESLSAARRTPIIG
                                                   . :::    .    .:   . :     * : . :.

Mflv_2141|M.gilvum_PYR-GCK          VIALLSLFYLFPT---LLGVFSRWYVPQLLITGTADAAVLLAP--GSAIG
Mvan_4562|M.vanbaalenii_PYR-1       VIALLSLFYLFPT---LLGVFSRLYVPQLLITGTADAAVLLAP--GSVIA
MSMEG_5161|M.smegmatis_MC2_155      VIALLSLFYLFPT---LLGVFSRLYVPQLLITGTADAAVLLAP--GAAIG
TH_3825|M.thermoresistible__bu      AAGGILLLCLPLS---FVALAAVGIVG----DSAGDGPILYA-----LLG
MAB_4639|M.abscessus_ATCC_1997      AFPKMFIPFIVVIPGMICAVLVPQMVAYKAGQPTSDPNLTYSNSLLYLMK
                                    .   : :  :      : .:     *       :.*  :  :      : 

Mflv_2141|M.gilvum_PYR-GCK          GAAGQLLAALVAAGAIAAFLATSSGLLVSFAGALATDVLPGRV-------
Mvan_4562|M.vanbaalenii_PYR-1       GVAGQLLAALVAAGAIAAFLATSSGLLVSFAGALATDVLPGRV-------
MSMEG_5161|M.smegmatis_MC2_155      GALGQLLAALVAAGAIAAFLATSSGLLVSIAGALATDVLRGRV-------
TH_3825|M.thermoresistible__bu      EYAPAWLAIIVISGLLAATLTTVSGILLSTASVLVRNVLR----------
MAB_4639|M.abscessus_ATCC_1997      EVLPNGVLGVAITGLLASFMAGMAANVSAFNTVFSYDLWQRYIRKDRPDG
                                          :  :. :* :*: ::  :. : :   .:  ::            

Mflv_2141|M.gilvum_PYR-GCK          --RDFRVAAVVGGLIPIPLALAASGDLELSRSVG-LAFAVAASTLCPLLV
Mvan_4562|M.vanbaalenii_PYR-1       --RDFRVAAVIGGLIPIPLALAASGELELSRSVG-LAFAVAASTLCPLLV
MSMEG_5161|M.smegmatis_MC2_155      --RDFRVAAVIGGIIPIPLSLFVSG-LELSRSVG-LAFAVAASTLCPLLV
TH_3825|M.thermoresistible__bu      --IDTGVLAPPAAMTPRMLRATRWATLPMAALAAVVALRVPQTGILLTLA
MAB_4639|M.abscessus_ATCC_1997      YYLRIGRIATVGATVIAIGTAFIAANYNNVMNYLQTLFAFFNAPLFATFI
                                            *  ..           .            : .  : :   : 

Mflv_2141|M.gilvum_PYR-GCK          LGIWWRGLTARGAMSGLAVGGLLSG-------GAVTVAVAGGIDENALGG
Mvan_4562|M.vanbaalenii_PYR-1       LGIWWRGLTATGAMAGLAVGGVLSG-------GAVTVAVAGGIDENVLGG
MSMEG_5161|M.smegmatis_MC2_155      LGIWWRRLTVVGAASGLVVGGVVCG-------SAVIIAIAGGVDENVLGG
TH_3825|M.thermoresistible__bu      FDLLLASLVVPFILGLYWSRGGAAA-------AAAAVVVGIGVRLTYFVL
MAB_4639|M.abscessus_ATCC_1997      LGMFWRRMTATAGWAGLVSGTFAAVGIWSLFETGVYTLAGQGSNFIEAGV
                                    :.:    :..    .        .         ..    . *        

Mflv_2141|M.gilvum_PYR-GCK          WPAVLIGYPAALSVPLAFATMILVSRFTRDEVP-PDVAQTFARMHVPENL
Mvan_4562|M.vanbaalenii_PYR-1       WPTVLVGYPAAVSVPLAFATMLAVSRLTRATAP-PDVAQTFARMHLPEHL
MSMEG_5161|M.smegmatis_MC2_155      WPAVMIGYPAAVSVPLAFLTMIVVSLATRTTLSGPTVAQIFARMHVPERL
TH_3825|M.thermoresistible__bu      APTIYGVDNTLLYLPNDWVSAXXRGGGPSGVRD--TPSDTPREMHPRNAL
MAB_4639|M.abscessus_ATCC_1997      AFTVDIVVSVAVSWTTEPKPAAELAGLVYSETPHAFSSDEPASGWFRQPV
                                      ::     . :  .    .    .            ::        : :

Mflv_2141|M.gilvum_PYR-GCK          GMGIERLPRA--------
Mvan_4562|M.vanbaalenii_PYR-1       GMGIERMPRA--------
MSMEG_5161|M.smegmatis_MC2_155      GMGVERLPQSR-------
TH_3825|M.thermoresistible__bu      A-----------------
MAB_4639|M.abscessus_ATCC_1997      KLAMTALILVVALNLIFH