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TSPPRTGGVVEELLQRSGRFFTPGDFSEDLRTVTRRGGRDGDVFYRDRWSHDKVVRSTHGVNCTGSCSWK VYVKDGIITWETQETDYPSVGPDRPEYEPRGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLGD PVLAWADIQADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTIKTYGPDRVAGFSPIPAMSMVSHA AGSRFVELVGGAMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDASYLMMWGSNVPVTRTPDAHWMAEV RYRGTKVVSVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILTENFVRRRVPFFVDYVRTYTDLPFLV KLEERDGVLVPGKMLTAADLGPGYDGQENAAFKPVLLDGATDSVVVPPGSLGFRYGDEGVGKWNLDLGDV VPALTVAPPDGQSGETTSISLTRFDTVDGRGATLQRGVPVRRVGEHRVCTVFDLMLAQYGVARPGLPGDW PAGYDDPDQPYTPAWQESITGVSASQAIRVAREFARNAEESGGRSMIIMGAGICQWFHGDTTYRAVLAML LLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAMATDWTRPPRQMPGTSYWYAHTGQWRYDGYRADALASP TARGRFAGKHTMDVVAAAAAMGWMPFYPQFDRNSLDVADEARAAGQDIGKYVCEKLASGELKMAVTDPDN PANWPRVLNVWRANLLGSSSKGNEYFLRHLLGADSNLQATPTEEALRPKDVTWPDDIPEGKLDLLMSVDF RMTSTTLLSDVVLPAATWYEKADLSSTDMHPYVHAFSPAIDPPWETRSDFEAFGAIARTFSTLARSHLGT RTDVVLGALQHDTPGAMAYPAGTQRDWRETGETPVPGKTIGPITVVERDYAAIADKWSTLGPLVERLGVT TKGVTTWPVQETAELAQKFGVLDSGPAAGQPAITTAERMADVILALSGTSNGRLAVEGFRELERRTGRPL AHLAEGSEERRITYADTQARPVPVITSPEWSGSETGGRRYAPFTVNIEALKPFHTLTGRMHFYLDHDWLE ELGEQLPVYRPPLDMARLFGEPAIGARGELGLTVRYLTPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSPA DAAKIQVRDNDWVEAVNRNGVLVCRAIVSHRMPEGVVYVYHAQERTIDVPLTETTGRRGGIHNSLTRLLV KPSHLAGGYAQTAFAFNYLGPTGNQRDEVTIVRRRSQEVVYQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4546 | - | - | 100% (1233) | nitrate reductase, alpha subunit |
M. vanbaalenii PYR-1 | Mvan_2438 | - | 9e-08 | 27.36% (201) | molybdopterin guanine dinucleotide-containing S/N-oxide |
M. vanbaalenii PYR-1 | Mvan_4442 | - | 6e-05 | 35.21% (71) | molydopterin dinucleotide-binding region |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1193 | narG | 0.0 | 80.16% (1235) | respiratory nitrate reductase subunit alpha NarG |
M. gilvum PYR-GCK | Mflv_2156 | - | 0.0 | 91.73% (1234) | nitrate reductase, alpha subunit |
M. tuberculosis H37Rv | Rv1161 | narG | 0.0 | 80.24% (1235) | respiratory nitrate reductase subunit alpha NarG |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3041 | - | 4e-07 | 27.87% (183) | putative biotin sulfoxide reductase BisC |
M. marinum M | MMAR_5195 | - | 2e-06 | 30.33% (122) | formate dehydrogenase, beta subunit, selenocysteine-containing |
M. avium 104 | MAV_1303 | - | 0.0 | 80.86% (1233) | nitrate reductase, alpha subunit |
M. smegmatis MC2 155 | MSMEG_5140 | - | 0.0 | 85.52% (1229) | nitrate reductase, alpha subunit |
M. thermoresistible (build 8) | TH_1885 | narX | 0.0 | 86.93% (1232) | PROBABLE NITRATE REDUCTASE NARX |
M. ulcerans Agy99 | MUL_3154 | - | 1e-05 | 25.00% (188) | dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1193|M.bovis_AF2122/97 MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW Rv1161|M.tuberculosis_H37Rv MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW MAV_1303|M.avium_104 MTATPHVGGVLEELLERSGRFFTPGEFSADLRTVTRQGGREADVFYRDRW Mvan_4546|M.vanbaalenii_PYR-1 MTSPPRTGGVVEELLQRSGRFFTPGDFSEDLRTVTRRGGRDGDVFYRDRW Mflv_2156|M.gilvum_PYR-GCK MSTPPRTGGVVEDLLARSGRFFTPGEFSDDLRTVTRRGGRDGDIFYRDRW TH_1885|M.thermoresistible__bu VTSPPRVGGPIEDLLQRSGRFFTPGDVSDDGRIVHRRGGREGDVFYRDRW MSMEG_5140|M.smegmatis_MC2_155 ----------MEELLQRSGRFFTPGTFSSDLRTVSRQGGREGDVFYRDRW MAB_3041|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M -------------------------------------------------- Mb1193|M.bovis_AF2122/97 SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP Rv1161|M.tuberculosis_H37Rv SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP MAV_1303|M.avium_104 SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP Mvan_4546|M.vanbaalenii_PYR-1 SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP Mflv_2156|M.gilvum_PYR-GCK SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP TH_1885|M.thermoresistible__bu SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP MSMEG_5140|M.smegmatis_MC2_155 SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQETDYPSVGPDRPEYEP MAB_3041|M.abscessus_ATCC_1997 ----MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDP MUL_3154|M.ulcerans_Agy99 ----------------MCGLEIRVADGLSGGRVVS--------------- MMAR_5195|M.marinum_M -----MGSNMAEAHPVGFQWVIEAKTRGAQVIHIDPRFTRTSAVADRHVP . . Mb1193|M.bovis_AF2122/97 RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWADIQ Rv1161|M.tuberculosis_H37Rv RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWADIQ MAV_1303|M.avium_104 RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWADIQ Mvan_4546|M.vanbaalenii_PYR-1 RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWADIQ Mflv_2156|M.gilvum_PYR-GCK RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARIGDPVLAWADIQ TH_1885|M.thermoresistible__bu RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLTDPVLAWADIQ MSMEG_5140|M.smegmatis_MC2_155 RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREARARLGDPVLAWADIQ MAB_3041|M.abscessus_ATCC_1997 S--------------------PLLQNIPGSIRHQARVTAPAVRSGWLREG MUL_3154|M.ulcerans_Agy99 -----------------------IRGNRDDVWSRGHICPKGASLGALHDD MMAR_5195|M.marinum_M ----------------------LRAGSDIAFLGGVINYILSNDLDFREYV . . Mb1193|M.bovis_AF2122/97 ADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAGFS Rv1161|M.tuberculosis_H37Rv ADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAGFS MAV_1303|M.avium_104 ADPERRRRYQRARGKGGLVRITWAEATELIAAAHVHTIKTYGPDRVAGFS Mvan_4546|M.vanbaalenii_PYR-1 ADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTIKTYGPDRVAGFS Mflv_2156|M.gilvum_PYR-GCK ADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTVKTYGPDRVAGFS TH_1885|M.thermoresistible__bu ADPQRRRRYQQARGKGGLVRISWAEATEMIAAAHVHTIKTHGPDRVAGFS MSMEG_5140|M.smegmatis_MC2_155 ADPERRRRYQSARGKGGLVRVSWAEATEMIAAAHVHTIKTYGPDRIAGFS MAB_3041|M.abscessus_ATCC_1997 PGPSDKR------GADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGS MUL_3154|M.ulcerans_Agy99 PD---RIRHPMIRIDGQWHEVSWDAAFRRCTELLAPVIDTYGIGAVTAYT MMAR_5195|M.marinum_M TAYTNAPFLVGEDYCDAEDLDGLFSGYDHASASYDPTTWRYQPGDHADPT . . : . : : Mb1193|M.bovis_AF2122/97 PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT Rv1161|M.tuberculosis_H37Rv PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT MAV_1303|M.avium_104 PIPAMSMVSYTAG---SRFFELIGAPMTSFYDWYADLP-VASPQVFGDQT Mvan_4546|M.vanbaalenii_PYR-1 PIPAMSMVSHAAG---SRFVELVGGAMTSFYDWYADLP-VASPQVFGDQT Mflv_2156|M.gilvum_PYR-GCK PIPAMSMVSHAAG---ARFVSLIGGAMTSFYDWYADLP-VASPQVFGDQT TH_1885|M.thermoresistible__bu PIPAMSMVSFAAG---SRFIELLGGVMTSFYDWYADLP-VASPQVFGDQT MSMEG_5140|M.smegmatis_MC2_155 PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT MAB_3041|M.abscessus_ATCC_1997 YGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIGTHD MUL_3154|M.ulcerans_Agy99 GNPLAHSFSLARY----------AGVLLGMSGMPVTYSPGTVDQWPKNLS MMAR_5195|M.marinum_M LQHPRCVYQILKRHYARYTPEMVERVCGVPAQSFLQVARAWTENSGRERT . : Mb1193|M.bovis_AF2122/97 DVPESGDWWDASYLVMWGSNVPITRTPDAHWMAEARYRGAKVVVVSPDYA Rv1161|M.tuberculosis_H37Rv DVPESGDWWDASYLVMWGSNVPITRTPDAHWMAEARYRGAKVVVVSPDYA MAV_1303|M.avium_104 DVPESGDWWDAAYLMMWGSNVPITRTPDAHWMAEARYRGTKVVTVSPDYA Mvan_4546|M.vanbaalenii_PYR-1 DVPESGDWWDASYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA Mflv_2156|M.gilvum_PYR-GCK DVPESGDWWDATYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA TH_1885|M.thermoresistible__bu DVPESGDWWDAAYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVAVSPDYA MSMEG_5140|M.smegmatis_MC2_155 DVPESGDWWDAAYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA MAB_3041|M.abscessus_ATCC_1997 GLFKRSTSWD---------------------------------------- MUL_3154|M.ulcerans_Agy99 SHLMYGGWWT---------------------------------------- MMAR_5195|M.marinum_M TALVYSVGWTQHS------------------------------------- . * Mb1193|M.bovis_AF2122/97 DNTKFADEWVRCAAGTDTALAMAMGHVILSECYVRNQVPFFVDYVRRYTD Rv1161|M.tuberculosis_H37Rv DNTKFADEWVRCAAGTDTALAMAMGHVILSECYVRNQVPFFVDYVRRYTD MAV_1303|M.avium_104 DNTKFADEWMPCAAGTDGALAMAMGHVILSECYVQKQVPFFTDYARRYTD Mvan_4546|M.vanbaalenii_PYR-1 DNTKFADEWMPCAAGTDGALAMAMGHVILTENFVRRRVPFFVDYVRTYTD Mflv_2156|M.gilvum_PYR-GCK DNTKFADEWMPCAAGTDGALAMAMGHVILTENYVRQRVPFFDEYVRTYTD TH_1885|M.thermoresistible__bu DNTKFADEWMPCAAGTDGAMAMAMGHVILSEFFVRKQVPFFTDYVRRYTD MSMEG_5140|M.smegmatis_MC2_155 DNTKFADEWMPCAAGTDGALAMAMGHVILSECFVQNEVPYFTDFARRFTD MAB_3041|M.abscessus_ATCC_1997 ------------VIVENTDLLIAFGGIALKNTGVNHGG------TTAHPA MUL_3154|M.ulcerans_Agy99 ---------FPEPDIERTGLLVIMDANPAASQGS---------LLAAPDV MMAR_5195|M.marinum_M ---------MGAQFIRAGSIIQLLLGNIGRPGGGIFALRGHASIQGSTDV : : Mb1193|M.bovis_AF2122/97 LPFLIKLEKRGDLLVPGKFLTAADIG---EESENAAFKPALLDELTNTVV Rv1161|M.tuberculosis_H37Rv LPFLIKLEKRGDLLVPGKFLTAADIG---EESENAAFKPALLDELTNTVV MAV_1303|M.avium_104 LPFLIKLEERGDMLVPGKNLTAADLG---EAVENAALKPALLDETTNSVA Mvan_4546|M.vanbaalenii_PYR-1 LPFLVKLEERDGVLVPGKMLTAADLGPGYDGQENAAFKPVLLDGATDSVV Mflv_2156|M.gilvum_PYR-GCK LPFLVKLEERGGVTVPGKMLTAADLGPAYGG-ENAEFKPALLNLATDSVT TH_1885|M.thermoresistible__bu LPFLVKLEERDGALVPGKMLTVADLGEVFGQHENAAFKPMLLDEATDTVT MSMEG_5140|M.smegmatis_MC2_155 LPFLAKLEERDGALVPGKNLTAADLTPDVAAQENAAFKPALLDSASDSIA MAB_3041|M.abscessus_ATCC_1997 RDALNRFRDRGGRIVSFS-------------------------------- MUL_3154|M.ulcerans_Agy99 MGLIDAIRQRGKVIVIDPVR------------------------------ MMAR_5195|M.marinum_M PTLFNLLPGYLDMPHAGQATLSDYLDN----------------------- : : Mb1193|M.bovis_AF2122/97 VPQGSLGFRFGEDGVGKWNLDLGSVVPALSVEMDKAVNGDRSAELVTLPS Rv1161|M.tuberculosis_H37Rv VPQGSLGFRFGEDGVGKWNLDLGSVVPALSVEMDKAVNGDRSAELVTLPS MAV_1303|M.avium_104 VPHGSLGFRYGESGVGKWNLDLGDLVPALSVRAAPTEDGE--TALVHLPS Mvan_4546|M.vanbaalenii_PYR-1 VPPGSLGFRYGDEGVGKWNLDLGDVVPALTVAPPDG--QSGETTSISLTR Mflv_2156|M.gilvum_PYR-GCK VPPGSLGFRYGDEGVGRWNLDLGDVVPALTVATGDV--HDGGSAAVTLSR TH_1885|M.thermoresistible__bu VPHGSLGFRYGTDGAGKWNLDLGPVVPALTVRTGD-----GPVTEVRLPC MSMEG_5140|M.smegmatis_MC2_155 IPQGSLGFRFGESGLGNWNLDLENLAPALTVAADT-----GETAEVTLPR MAB_3041|M.abscessus_ATCC_1997 ------PLHDDIDGECEWHAPIPGTDVAVMLALAHV-------------- MUL_3154|M.ulcerans_Agy99 --------TVTAARADEWLPIVPGTDAALLLAVAHT-------------- MMAR_5195|M.marinum_M --------IKSRNQKGFWHNADAYMVSLLKEYWGEH-------------- * : Mb1193|M.bovis_AF2122/97 FDTIDGHGETVSRGLPVRRAGKHLVCTVFDLMLAHYGVARAGLPGEWPTG Rv1161|M.tuberculosis_H37Rv FDTIDGHGETVSRGVPVRRAGKHLVCTVFDLMLAHYGVARAGLPGEWPTG MAV_1303|M.avium_104 FDTVDGEGTTVARGVPVRRVGKHLVCTVFDLMLAQYGVARPGLPGEWPTG Mvan_4546|M.vanbaalenii_PYR-1 FDTVDGRGATLQRGVPVRRVGEHRVCTVFDLMLAQYGVARPGLPGDWPAG Mflv_2156|M.gilvum_PYR-GCK FDTVDGHGATMLRGVPVRQVGAHRVCTVFDLMLAQYGVARPGLPGDWPTG TH_1885|M.thermoresistible__bu FDSVDGHGTTVTRGVPVRHVGDHRVCTVFDLMLAQYGVSRPGLPGDWPTG MSMEG_5140|M.smegmatis_MC2_155 FDTLDGHGDTMVRGVPVRRVGEHLVCTVFDLMLAQYGVARPGLPGDWPTG MAB_3041|M.abscessus_ATCC_1997 --------------LAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPK- MUL_3154|M.ulcerans_Agy99 ---------------------------LFDEDLVNPGQHVDGVD------ MMAR_5195|M.marinum_M -----------------ATADNDYCFDYLPRINGDHSTYRTVMDMIDGKV : Mb1193|M.bovis_AF2122/97 YHDRTQQNTPAWQESITGVPAAQAIRFAKEFARNATESGGRSMIIMGGGI Rv1161|M.tuberculosis_H37Rv YHDRTQQNTPAWQESITGVPAAQAIRFAKEFARNATESGGRSMIIMGGGI MAV_1303|M.avium_104 YDDATQQNTPAWQEAITGVSAAQATRVAREFARSAEESGGRSMIIMGGGI Mvan_4546|M.vanbaalenii_PYR-1 YDDPDQPYTPAWQESITGVSASQAIRVAREFARNAEESGGRSMIIMGAGI Mflv_2156|M.gilvum_PYR-GCK YDDPRSPYTPAWQEPITGVSAGQAIRVAREFARNAEESGGRSMIIMGAGI TH_1885|M.thermoresistible__bu YDDATRPYTPAWQEPITGVSAAQVIRIATEFARNAEESGGRSMIIMGAGI MSMEG_5140|M.smegmatis_MC2_155 FDDATRPYTPAWQEPITGVAAAQAIRVAREFARNAEETRGRSMIIMGAGI MAB_3041|M.abscessus_ATCC_1997 --------SPEWAAPISGLDAAELRTLARRMAA------GRTLVTVSWSL MUL_3154|M.ulcerans_Agy99 --------------------------TMRRVAGSSRDKTARKVFSLGR-- MMAR_5195|M.marinum_M FGYFLLGQNPAVGSAHGRMQRLGMANLDWLVVRDLVMIESATFWKEAPEV .. . .. . Mb1193|M.bovis_AF2122/97 CHWFHSDVMYRSVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGWQTMAM Rv1161|M.tuberculosis_H37Rv CHWFHSDVMYRSVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGWQTMAM MAV_1303|M.avium_104 CHWFHSDAIYRAVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGFQTMAM Mvan_4546|M.vanbaalenii_PYR-1 CQWFHGDTTYRAVLAMLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAM Mflv_2156|M.gilvum_PYR-GCK CQWFHGDTTYRAVLAMLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMGS TH_1885|M.thermoresistible__bu CQWFHGDATYRAVLALLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAM MSMEG_5140|M.smegmatis_MC2_155 CQWFHGDATYRAVLALLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAM MAB_3041|M.abscessus_ATCC_1997 QRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYG--------------S MUL_3154|M.ulcerans_Agy99 ----RNRTPNWANTSSEAVAAHVAKPA----------------------- MMAR_5195|M.marinum_M ETGEISPQTCRTEVFFFPAASHVEKAG--------------------TFT . . : . Mb1193|M.bovis_AF2122/97 ATDWSRPPRQVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFAGKHTMD Rv1161|M.tuberculosis_H37Rv ATDWSRPPRQVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFAGKHTMD MAV_1303|M.avium_104 ATDWVRPPRQVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFAGRHTMD Mvan_4546|M.vanbaalenii_PYR-1 ATDWTRPPRQMPGTSYWYAHTGQWRYDGYRADALASPTARGRFAGKHTMD Mflv_2156|M.gilvum_PYR-GCK ALDWSRPPRQMPGTSYWYAHTDQWRYDGYRADTLASPTARGRFTGKHTMD TH_1885|M.thermoresistible__bu ATDWSRPPRQMPGTSYWYVHTDQWNYDGYRADALASPIGRGRFRGKHTMD MSMEG_5140|M.smegmatis_MC2_155 ATDWSRPPRQMAGTSYWYAHTDQWRYDGYQADALSSPVGRGRFRGRHTMD MAB_3041|M.abscessus_ATCC_1997 MNEPGLAPVSCPLPTFP--------------------------QGPNPVE MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M QTQRMLQWREKAVDPPGDARSELWFFYHLGRKLREKLSGSTDERDRPLLQ Mb1193|M.bovis_AF2122/97 LLTSATAMGWSPFYPQFDRSSLDVADEARAAGRDVGDYVAEQLAQHKLKL Rv1161|M.tuberculosis_H37Rv LLTSATAMGWSPFYPQFDRSSLDVADEARAAGRDVGDYVAEQLAQHKLKL MAV_1303|M.avium_104 LLASAVAMGWSPYYPQFDRSSLDVADEARAAGRDVADYVAEQLGRRNLKL Mvan_4546|M.vanbaalenii_PYR-1 VVAAAAAMGWMPFYPQFDRNSLDVADEARAAGQDIGKYVCEKLASGELKM Mflv_2156|M.gilvum_PYR-GCK VVAAAAAMGWMPFYPQFDRNSLDIADEALAAGRDIPQYLCEKLASGELKM TH_1885|M.thermoresistible__bu VLASATAMGWSPFYPQFDRSSLDIADEARAAGKEIGAYVCEQLASGGLKL MSMEG_5140|M.smegmatis_MC2_155 VLASAAAMGWSPFFPQFDRSSLDVADEARAADQEIPAYVTAKLADGSLKL MAB_3041|M.abscessus_ATCC_1997 TFIPVAAISELLLRPGQ-----------------TLAYNGQTLTLPDIRC MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M LAWDYATEGDEPSGEDVLRHMNGIDLGTGRTIDGYPSLKADGSTACGCWI Mb1193|M.bovis_AF2122/97 SITDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNVQSDPPT Rv1161|M.tuberculosis_H37Rv SITDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNVQSDPPT MAV_1303|M.avium_104 AVTDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNASAVPPE Mvan_4546|M.vanbaalenii_PYR-1 AVTDPDNPANWPRVLNVWRANLLGSSSKGNEYFLRHLLGADSNLQATPTE Mflv_2156|M.gilvum_PYR-GCK AVTDPDNPANWPRVLNVWRANLLGSSSKGNEYFLRHLLGTDSNLQASPTP TH_1885|M.thermoresistible__bu AVTDPDDPRNWPRVLSVWRSNLLGSSSKGNEYFLRHLLGTDSNLRATRTP MSMEG_5140|M.smegmatis_MC2_155 AVTDPDNPANWPRVLDVWRANLLGSSSKGNEYFLRHLLGTTSNLQAAPN- MAB_3041|M.abscessus_ATCC_1997 VYWAGGNPFHHHQNLPRLRRALS--------------------------- MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M YSGVYADEVNQAARRKPR-------------------------------- Mb1193|M.bovis_AF2122/97 DGVHPRDVVWDSDIPEGKLDLIMSIDFRMTSTTLVSDVVLPAATWYEKSD Rv1161|M.tuberculosis_H37Rv DGVHPRDVVWDSDIPEGKLDLIMSIDFRMTSTTLVSDVVLPAATWYEKSD MAV_1303|M.avium_104 DGVRPVDVTCGADIPEGKLDLMMSIDFRMTSTTLVSDVVLPAATWYEKAD Mvan_4546|M.vanbaalenii_PYR-1 EALRPKDVTWPDDIPEGKLDLLMSVDFRMTSTTLLSDVVLPAATWYEKAD Mflv_2156|M.gilvum_PYR-GCK EALRPADVVWPDDIPEGKLDLLMSIDFRMTSTTLLSDVVLPAATWYEKAD TH_1885|M.thermoresistible__bu EALRPNDVRSPDEIPEGKLDLLMSIDFRMTSTTLLSDIVLPAATWYEKHD MSMEG_5140|M.smegmatis_MC2_155 -GVRPSSVTCTDDIPEGKLDLLMSIDFRMTSTTLLSDVVLPAATWYEKAD MAB_3041|M.abscessus_ATCC_1997 -----------------RVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M -------------------DEQRPYENEWGWTWPLNRRVLYNRASADPQG Mb1193|M.bovis_AF2122/97 LSSTDMHPYVHSFSPAIDPPWETRSDFGAFAAIARAFSALAKRHLGTRTD Rv1161|M.tuberculosis_H37Rv LSSTDMHPYVHSFSPAIDPPWETRSDFDAFAAIARAFSALAKRHLGTRTD MAV_1303|M.avium_104 ISSTDMHPYVHAFSAATDPPWETRSDFDAFGAIARAFSTMAKEHLGTRTD Mvan_4546|M.vanbaalenii_PYR-1 LSSTDMHPYVHAFSPAIDPPWETRSDFEAFGAIARTFSTLARSHLGTRTD Mflv_2156|M.gilvum_PYR-GCK LSSTDMHPYVHAFSPAIDPPWETRSDFDAFGAVASAFSALARTHLGTRTD TH_1885|M.thermoresistible__bu LSSTDMHPYVHAFSPAIDPPWETRSDYDAFGAIARAFSALARKHLGTRTD MSMEG_5140|M.smegmatis_MC2_155 LSSTDMHPYVHAFSPAVDPPWETRSDFEAFGAIARAFSTLAARHLGVRTD MAB_3041|M.abscessus_ATCC_1997 FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAA MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M RPWSERKKLVWWDAELGEWTGHDVPDFEKHKAPDYRPPAGAVGVEALRGD Mb1193|M.bovis_AF2122/97 VVLTALQHDTPDEMAYPDGTERDWLATGEVPVPGRTMSKLTVVERDYTAI Rv1161|M.tuberculosis_H37Rv VVLTALQHDTPDEMAYPDGTERDWLATGEVPVPGRTMSKLTVVERDYTAI MAV_1303|M.avium_104 VVLTALQHDTPDAMAYPDGAEHDWLRSGATPVPGRTMGKLTVVERDYAAV Mvan_4546|M.vanbaalenii_PYR-1 VVLGALQHDTPGAMAYPAGTQRDWRETGETPVPGKTIGPITVVERDYAAI Mflv_2156|M.gilvum_PYR-GCK VVLGALQHDTPGAMAYPAGTQRDWRETGEVPVPGATIGPIAVVERDYTAI TH_1885|M.thermoresistible__bu VVLGALQHDTPGAMAYAGGTERDWRVTGEVPVPGKTIGPLAVVERDYTAI MSMEG_5140|M.smegmatis_MC2_155 VVLGTLQHDTLGAMAYPSGTEHDWRVTGETPVPGRTMGPLAVVERDYGAI MAB_3041|M.abscessus_ATCC_1997 QWLRHIYTEWAGALNFSVPSFDEFWDRGYLELP----------------- MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M DAF-VMQADGKGWLFAPSGLADGPLPTHYEPHESPVRNALYAQ------- Mb1193|M.bovis_AF2122/97 YDKWLTLGPLIDQFGMTTKGYTVHPFREVSELAANFGVMNSGVAVGRPAI Rv1161|M.tuberculosis_H37Rv YDKWLTLGPLIDQFGMTTKGYTVHPFREVSELAANFGVMNSGVAVGRPAI MAV_1303|M.avium_104 YDKWRTLGPLVDKFGLTTKGVTVHPFREVEELAARFGVLKSGVAAGRPAI Mvan_4546|M.vanbaalenii_PYR-1 ADKWSTLGPLVERLGVTTKGVTTWPVQETAELAQKFGVLDSGPAAGQPAI Mflv_2156|M.gilvum_PYR-GCK ADKWSTLGPLVEKLGLTTKGVTTHPDREADELARKFGVFDSGPAAGRPAI TH_1885|M.thermoresistible__bu ADKWAALGPLVEELGVTTKGVTTWPVQEVAELAKAFGVMDSGPAAGRPAI MSMEG_5140|M.smegmatis_MC2_155 AQKWAALGPLVEGLGVTTKGLTTHPTREVAELGAKFGVMDSGAAQGRPAI MAB_3041|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M -------------------------------------------------- Mb1193|M.bovis_AF2122/97 TTAKRMADVILALSGTCNGRLAVEGFLELEKRTGQRLAHLAEGSEERRIT Rv1161|M.tuberculosis_H37Rv TTAKRMADVILALSGTCNGRLAVEGFLELEKRTGQRLAHLAEGSEERRIT MAV_1303|M.avium_104 TTAARMADVLLLLSGTTNGRLAVEGFHELEKRTGQRLVHLAEGSEDKRIS Mvan_4546|M.vanbaalenii_PYR-1 TTAERMADVILALSGTSNGRLAVEGFRELERRTGRPLAHLAEGSEERRIT Mflv_2156|M.gilvum_PYR-GCK TTAERMADVILALSGTSNGRLAVEGFRELQRRTGTPLAHLAEGSEERRIT TH_1885|M.thermoresistible__bu TTAARMAEVILALSGTSNGRLAVEGFRELEKRTGQRLAQLAEGSEERRIT MSMEG_5140|M.smegmatis_MC2_155 TTGERMADVILALSGTSNGRLAVEGFAELERRTGRKLVHLALGSEERRIT MAB_3041|M.abscessus_ATCC_1997 ---------------TDAGLTLLSDFRE---------------------- MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M ---------------QGNPTRIVFGRKD---------------------- Mb1193|M.bovis_AF2122/97 YADTQARPVPVITSPEWSGSESGGRRYAPFTINIEHLKPFHTLTGRMHFY Rv1161|M.tuberculosis_H37Rv YADTQARPVPVITSPEWSGSESGGRRYAPFTINIEHLKPFHTLTGRMHFY MAV_1303|M.avium_104 YADTQARPVPVVTSPEWSGSETGGRRYAPFTINIENLKPFHTLTGRMHFY Mvan_4546|M.vanbaalenii_PYR-1 YADTQARPVPVITSPEWSGSETGGRRYAPFTVNIEALKPFHTLTGRMHFY Mflv_2156|M.gilvum_PYR-GCK YADTQARPVPVITSPEWSGSETGGRRYAPFTVNIEQLKPFHTLTGRMHFY TH_1885|M.thermoresistible__bu FADTQARPVPVITSPEWSGSETAGRRYAPFTVNIEHLKPFHTLTGRMHFY MSMEG_5140|M.smegmatis_MC2_155 YADAQARPVPVITSPEWSGSETGGRRYAPFTVNIEELKPFHTLTGRMHFY MAB_3041|M.abscessus_ATCC_1997 -------------NPAAHPLHTPSGRIEIFSETIDGFG-YSDCGGHPQWY MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M -------------NPSNPSPPEAHGEVFPFVFTAARLTEHHTAGG----- Mb1193|M.bovis_AF2122/97 LAHDWVEELGEQLPVYRPPLDMARLFNQPELG-----PTDDGLGLTVRYL Rv1161|M.tuberculosis_H37Rv LAHDWVEELGEQLPVYRPPLDMARLFNQPELG-----PTDDGLGLTVRYL MAV_1303|M.avium_104 LAHDWVEELGEHLPVFRPPLDMARLFGQPRLG-----ACEDGIGLTVRYL Mvan_4546|M.vanbaalenii_PYR-1 LDHDWLEELGEQLPVYRPPLDMARLFGEPAIG----ARG--ELGLTVRYL Mflv_2156|M.gilvum_PYR-GCK LDHDWLEELGEQLPVYRPPLDLGRLFGEPAIG----APGATGVGLTVRYL TH_1885|M.thermoresistible__bu LDHDWLEELGEQLPVYRPPLDMARLFGAQQIG----HSD--GVGLTVRYL MSMEG_5140|M.smegmatis_MC2_155 VDHDWLEELGEQLPVYRPPLDMARLFGESRLGAGPGADGAGGVGLTVRYL MAB_3041|M.abscessus_ATCC_1997 EPTEWLGGERAQR------FPLHLIANQPRTR------------------ MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M --------MSRQLPYLTELQPALFMEVSPELAR----------------- Mb1193|M.bovis_AF2122/97 TPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSPGDAAKINVRDNDWVEAVN Rv1161|M.tuberculosis_H37Rv TPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSPGDAAKINVRDNDWVEAVN MAV_1303|M.avium_104 TPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSPGDAAKIQVRDNDWVEAVN Mvan_4546|M.vanbaalenii_PYR-1 TPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSPADAAKIQVRDNDWVEAVN Mflv_2156|M.gilvum_PYR-GCK TPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSPADAEKIEVRDNDWVEAVN TH_1885|M.thermoresistible__bu TPHSKWSIHSEYQDNLLMLSLSRGGPTMWMSPADAAKIGVADNDWVEAVN MSMEG_5140|M.smegmatis_MC2_155 TPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSPGDADKIAVRDNDWVEAVN MAB_3041|M.abscessus_ATCC_1997 -LHSQLDFGGTSQG-----SKVRGREPLRIHPQDAATRGIADGDVVRVFN MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M -------MRGLTHMDWAHVITSRTAVDARVFVTDRMRPLRIEDHVVQQVW Mb1193|M.bovis_AF2122/97 ANGIYVCRAIVSHRMPEGVVFVYHVQERTVDTPRTETNGKRGGNHNALTR Rv1161|M.tuberculosis_H37Rv ANGIYVCRAIVSHRMPEGVVFVYHVQERTVDTPRTETNGKRGGNHNALTR MAV_1303|M.avium_104 ANGIYVCRAIVSHRMPDGVVYVYHVQERTVDTPRTETNDKRGGNHNALTR Mvan_4546|M.vanbaalenii_PYR-1 RNGVLVCRAIVSHRMPEGVVYVYHAQERTIDVPLTETTGRRGGIHNSLTR Mflv_2156|M.gilvum_PYR-GCK RNGVLVCRAIVSHRMPEGVVYVYHAQERTIDVPLTETTGRRGGIHNSLTR TH_1885|M.thermoresistible__bu PNGVLVCRAIVSHRMPEGVVYVYHVQERTIDVPIAETTGKRGGIHNSLTR MSMEG_5140|M.smegmatis_MC2_155 RNGVLVCRAIVSHRMPDGVVYVYHAQERTIDVPLTETTGTRGGIHNSLTR MAB_3041|M.abscessus_ATCC_1997 DRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNSACAHGNPNVLTD MUL_3154|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5195|M.marinum_M MPYHWGYTGLVEGDVVNDLLGVVLDPNVFIQESKVATCDVQPGRRPRGPA Mb1193|M.bovis_AF2122/97 VRIKPSHLAGGYGQHAFAFNYLGPTGNQRDEVTVVRRRSQEVRY- Rv1161|M.tuberculosis_H37Rv VRIKPSHLAGGYGQHAFAFNYLGPTGNQRDEVTVVRRRSQEVRY- MAV_1303|M.avium_104 VRIKPSHLAGGYAQHAFAFNYLGPTGNQRDEVTIVRRRSQEVVY- Mvan_4546|M.vanbaalenii_PYR-1 LLVKPSHLAGGYAQTAFAFNYLGPTGNQRDEVTIVRRRSQEVVYQ Mflv_2156|M.gilvum_PYR-GCK LLVKPSHLAGGYAQTAFAFNYLGPTGNQRDEVTVVRRRSQEVVY- TH_1885|M.thermoresistible__bu LLIKPSHLAGGYAQNAFAFNYLGPTGNQRDEVTVVRRRSQRVVF- MSMEG_5140|M.smegmatis_MC2_155 LLIKPSHLAGGYAQHSYAFNYLGPTGNQRDEVTVVRRRSQEVTYR MAB_3041|M.abscessus_ATCC_1997 DSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD--- MUL_3154|M.ulcerans_Agy99 --------------------------------------------- MMAR_5195|M.marinum_M LLDYIAEYRRRAGITTETGTHLDTTRDDGIAHPDPEESP------