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RRDLFTEDHEAFRELARDFVDKEVVPHYPQWEKGGRMPREVFERMGGLGILGVAIPEEYGGGGQPDYRYN VVLQEEAARALVTLSTVRTQLEVILPYFLHYANDEQRDRWFPGLASGTVLTAIAMTEPGTGSDLAGMRTT AVRDGDDYIVNGAKTFITGGMQADLVIVVARTSTDPDNRRKGLTLLVVEDGMDGFTRGRELEKMGCKVQD TAELSFVDVRVPAANVLGEVDEAFGYLGHNLAQERLTVAVGSVAQARSAIAAAIEYTQSRKAFGTPVASF QNTKFELAACSTEVEAAQAMLDRAVSLHVEGELSGADAARTKLFCTEMQQRVVDRCLQLFGGYGYMMEYP IARLYTDARVARIYAGTSEVMKVMIAKSLGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4205 | - | - | 100% (382) | acyl-CoA dehydrogenase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2439 | - | e-110 | 50.79% (380) | long-chain-acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4587 | - | e-108 | 47.91% (382) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-105 | 49.34% (381) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2446 | - | 0.0 | 95.60% (386) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-107 | 49.61% (381) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 8e-56 | 32.89% (380) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3040c | - | 1e-108 | 51.45% (379) | acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1989 | fadE20 | 1e-107 | 49.08% (381) | acyl-CoA dehydrogenase FadE20 |
| M. avium 104 | MAV_1883 | - | 1e-111 | 50.00% (382) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4832 | - | 0.0 | 88.22% (382) | acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3610 | - | 0.0 | 86.91% (382) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-106 | 48.82% (381) | acyl-CoA dehydrogenase FadE20 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4205|M.vanbaalenii_PYR-1 ---------MRRDLFTEDHEAFRELARDFVDKEVVPHYPQWEKGGRMPRE
Mflv_2446|M.gilvum_PYR-GCK ---------MRRDLFTEDHEAFRELARDFVEKEVVPHYPDWEKGGRMPRP
MSMEG_4832|M.smegmatis_MC2_155 ---------MQRNLFTEDHEAFRTLARDFIEKEVVSAYPEWEKAGRMPRD
TH_3610|M.thermoresistible__bu ---------VRREVFTDDHEAFRELARDFIEKEVVPNYPDWEKAGRMPRE
MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MAB_3040c|M.abscessus_ATCC_199 ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA
MAV_1883|M.avium_104 ---------MKRLVLESEHEAFRETVRQFIDQELVPNAEKWETNRLVDRS
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
: :*: :* : : ::. . : . .
Mvan_4205|M.vanbaalenii_PYR-1 VFERMGGLGILGVAIPEEYGGGGQPDYRYNVVLQEEAARALVTLSTVRTQ
Mflv_2446|M.gilvum_PYR-GCK VFEQMGSLGILGVAIPEEYGGGGQPDYRYNVVLQEEAARALVTLSTVRTQ
MSMEG_4832|M.smegmatis_MC2_155 VFKQMGELGMLGMAIPEEYGGAGIPDYRYNVVLQEEAARALVTLSTVRTQ
TH_3610|M.thermoresistible__bu AFELMGSLGMLGMAIPEQYGGAGIVDYRYNVVLQEEAARALVTLSTVRTQ
MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
MAB_3040c|M.abscessus_ATCC_199 LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLH
MAV_1883|M.avium_104 AWVAAGKYGLIGFNMPEQYGGSGVDDFRFNAVIDEEIARYGGPAPALSLQ
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIPAV
. *: . :**::** * * :: ** . .
Mvan_4205|M.vanbaalenii_PYR-1 LEVILPYFLHYANDEQRDRWFPGLASGTVLTAIAMTEPGTGSDLAGMRTT
Mflv_2446|M.gilvum_PYR-GCK LEVILPYFLHYANAEQRERWFPGLASGTLLTAIAMTEPGTGSDLAGMRTT
MSMEG_4832|M.smegmatis_MC2_155 LEVILPYFLHYADTEQRQRWFPGLAAGTLLTAIAMTEPGTGSDLAGVRTT
TH_3610|M.thermoresistible__bu LDVILPYFLHYADEEQRARWFPGLAAGKLLTAIAMTEPGTGSDLAGVRTT
MMAR_1989|M.marinum_M NDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
MUL_3367|M.ulcerans_Agy99 NEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
Mb2743c|M.bovis_AF2122/97 NDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTR
Rv2724c|M.tuberculosis_H37Rv NDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITTR
MAB_3040c|M.abscessus_ATCC_199 NDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTR
MAV_1883|M.avium_104 NDVVGPYFSSLSNDEQKERWLPGITTGELIVAVAMTEPGAGSDLAGIRTS
MLBr_00737|M.leprae_Br4923 NKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTR
.: : . * : : :* : : : *::* :*** .: *
Mvan_4205|M.vanbaalenii_PYR-1 AVRDGD----DYIVNGAKTFITGGMQADLVIVVARTSTDPDNRRKGLTLL
Mflv_2446|M.gilvum_PYR-GCK AVRDGSGPDADYIVNGAKTFITGGMQADLVIVVARTSTDPDNRRKGLTLL
MSMEG_4832|M.smegmatis_MC2_155 AVRDGD----HYVVNGAKTFITGGIQADLVVVVARTSTDPDNRRKGLTLL
TH_3610|M.thermoresistible__bu AVRDGD----DYILNGAKTFITGGIQADLVIVVARTSTDPDNRRRGLTLL
MMAR_1989|M.marinum_M AVKQGD----HYLLNGSKTFITNGINADLVIVVAQT--DPEKGAQGFSLL
MUL_3367|M.ulcerans_Agy99 AVKQGD----HYLLNGSKTFITNGINADLVIVVAQT--DPEKGAQGFSLL
Mb2743c|M.bovis_AF2122/97 AVKHGD----HYVLNGSKTFITNGINSDLVIVVAQT--DPEKGAQGFSLL
Rv2724c|M.tuberculosis_H37Rv AVKHGD----HYVLNGSKTFITNGINSDLVIVVAQT--DPEKGAQGFSLL
MAB_3040c|M.abscessus_ATCC_199 AVKDGD----HYILNGAKTFITNGINADLVIVVAQT--DPEKGALGFSLI
MAV_1883|M.avium_104 AVRDGD----DWIINGAKTFISSGINCDLVVVVCRT--DPDAGHKGFTLF
MLBr_00737|M.leprae_Br4923 AKADGD----DWILNGFKCWITNGGKSTWYTVMAVT--DPDKGANGISAF
* .*. .:::** * :*:.* :. *:. * **: *:: :
Mvan_4205|M.vanbaalenii_PYR-1 VVEDGMDGFTRGRELEKMGCKVQDTAELSFVDVRVPAANVLGEVDEAFGY
Mflv_2446|M.gilvum_PYR-GCK VVEDGMEGFTRGRELEKMGCKVQDTAELSFVDVRVPAANVLGEVDEAFGY
MSMEG_4832|M.smegmatis_MC2_155 VVEDGMAGFSRGRELEKMGCKVQDTAELSFTDVRVPVANVLGEEGEAFSY
TH_3610|M.thermoresistible__bu VVEDGMPGFTRGRELEKMGCKVQDTAELSFTDVRVPVANRLGEEGEAFSY
MMAR_1989|M.marinum_M VVERGMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIY
MUL_3367|M.ulcerans_Agy99 VVERGMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIY
Mb2743c|M.bovis_AF2122/97 VVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIY
Rv2724c|M.tuberculosis_H37Rv VVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIY
MAB_3040c|M.abscessus_ATCC_199 VVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIY
MAV_1883|M.avium_104 VVEAGMDGFTRGRKLDKMGLHYQDTAELNFDNVRVPSANLLGKEGRGFYH
MLBr_00737|M.leprae_Br4923 IVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKT
:*. . ** * . .*:* . . *:** * . :* . :*: . .*
Mvan_4205|M.vanbaalenii_PYR-1 LGHNLAQERLTVAVGSVAQARSAIAAAIEYTQSRKAFGTPVASFQNTKFE
Mflv_2446|M.gilvum_PYR-GCK LGHNLAQERLTVAVGSVAQARSAIAAAIDYTRNRKAFGTPVASFQNTKFE
MSMEG_4832|M.smegmatis_MC2_155 LGHNLAQERLTVAVGSVAQARSAIDAAIDYTKTRKAFGTPVASFQNTKFE
TH_3610|M.thermoresistible__bu LGHNLAQERMTVAVGSVAQARSAIDTTIEYVKSRKAFGTPVASFQNTKFE
MMAR_1989|M.marinum_M LMQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFV
MUL_3367|M.ulcerans_Agy99 LMQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFV
Mb2743c|M.bovis_AF2122/97 LMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFL
Rv2724c|M.tuberculosis_H37Rv LMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFL
MAB_3040c|M.abscessus_ATCC_199 LMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFL
MAV_1883|M.avium_104 LMHNLPSERLSIAISAIAGARETWRQTLQYAKDRKAFGQPIGSFQHNRFM
MLBr_00737|M.leprae_Br4923 ALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFM
.* * ::. : . . . :: *. ** ** .: .** :*
Mvan_4205|M.vanbaalenii_PYR-1 LAACSTEVEAAQAMLDRAVSLHVEGE-LSGADAARTKLFCTEMQQRVVDR
Mflv_2446|M.gilvum_PYR-GCK LAACSTEVEAAQAMLDRAVSLHVEGE-LSGADAARTKLFCTEMQQRVVDR
MSMEG_4832|M.smegmatis_MC2_155 LAACSAEVEAAQAMLDRAVALHVDGE-LSGADAARVKLFCTEMQARVVDR
TH_3610|M.thermoresistible__bu LAACSAEVEAAQAMLDRAVLDLVDGQ-LSGADAARVKLFCTEMQARVVDR
MMAR_1989|M.marinum_M LAELATEATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDR
MUL_3367|M.ulcerans_Agy99 LAELATEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDR
Mb2743c|M.bovis_AF2122/97 LAELATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDR
Rv2724c|M.tuberculosis_H37Rv LAELATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDR
MAB_3040c|M.abscessus_ATCC_199 LAELATDATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDR
MAV_1883|M.avium_104 LAEMDTELEIGEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTETAKKVIDG
MLBr_00737|M.leprae_Br4923 LADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTD
** . . : : :* * :.:: :
Mvan_4205|M.vanbaalenii_PYR-1 CLQLFGGYGYMMEYPIARLYTDARVARIYAGTSEVMKVMIAKSLGL
Mflv_2446|M.gilvum_PYR-GCK CLQLFGGYGYMMEYPIARLYTDARVARIYAGTSEVMKVMIAKSLGL
MSMEG_4832|M.smegmatis_MC2_155 CLQLFGGYGYMMEYPIARLYTDARVARIYAGTSEVMKVIIAKSLGL
TH_3610|M.thermoresistible__bu CLQLFGGYGYMMEYPIARLYTDARVARIYAGTSEVMKVIIAKSLGL
MMAR_1989|M.marinum_M CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MUL_3367|M.ulcerans_Agy99 CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
Mb2743c|M.bovis_AF2122/97 CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv CLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MAB_3040c|M.abscessus_ATCC_199 CLQLHGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL--
MAV_1883|M.avium_104 CVQLHGGYGYMTEYRVARDYMDNRIMTIFGGTTEIMKDIIGRDLGL
MLBr_00737|M.leprae_Br4923 AVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
.:**.** *: :: : * * :: *: **.:: : ::.: *