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KEFSDGSSGVARVPVIDASVHIFCQSNKDLRKNFLREPFRSRGFPDYEMDWYGAPGGEYAPRTEGPDGQY PGSDPELVAKHLFTDRGVDLAILHPMTRGIMPDRHLGTAIASAHNEMMVTRWLDHPEFGERFRGTLRVNP DDIAGALREIDKYRDHPRIVQLGIPLQSREVYGKPQFWPLWEAAVDAGWPVAVHFEVGSGVALPPTPNGL TRTYEQYVGFTALNFLYHLMNMIAEGVFERMPDLKFVWADGAADLLTPFMWRMDCFGRPHLEQTPWAPRM PSDYLPGHVFFVQGALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQLNELTVPGSYDPEQRDKLCWRN AAQLYGIQSPAISVPAAAQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2490 | - | - | 100% (370) | amidohydrolase 2 |
| M. gilvum PYR-GCK | Mflv_2489 | - | 2e-34 | 29.23% (349) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4724 | - | 1e-169 | 74.04% (366) | metal-dependent hydrolase |
| M. avium 104 | MAV_0930 | - | 1e-172 | 75.68% (370) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_4807 | - | 0.0 | 80.86% (350) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_4618 | - | 0.0 | 82.16% (370) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4164 | - | 0.0 | 87.00% (377) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2490|M.gilvum_PYR-GCK -MKEFSDGSSG----VARVPVIDASVHIFCQSNKDLRKNFLREPFRSRGF
Mvan_4164|M.vanbaalenii_PYR-1 -MKVLSDGSAGALEAQVKVPVIDASVHIFCQSNKDLRRNFLQEPFRSRGF
MSMEG_4807|M.smegmatis_MC2_155 -------------------------MHIFFGSNKDLRQNFLREPFASRGF
TH_4618|M.thermoresistible__bu -VIELSDG--------TRTPVIDASVHIFCKSNKDLRGTFLREPFKSRGF
MMAR_4724|M.marinum_M MVIEHADG--------TRMPVIDASVHIFFPSNKDLR-SFLREPFKSRGF
MAV_0930|M.avium_104 -MIEHADG--------TRTPVIDASVHIFFPSNKDLR-SFLREPFKSRGF
:*** ****** .**:*** ****
Mflv_2490|M.gilvum_PYR-GCK PDYEMDWYGAPGGEYAPRTEGPDGQYPGSDPELVAKHLFTDRGVDLAILH
Mvan_4164|M.vanbaalenii_PYR-1 PDYEMDWYGAPGGEYAERTTGPDDQYPGSDPEVVAKHLFTDRGVDIAVLH
MSMEG_4807|M.smegmatis_MC2_155 PDYEMNWYGAPGGEYAKNTKGPDRQYPGSDPDVAAQHLFTERGVDIAILH
TH_4618|M.thermoresistible__bu PDYEMDWYGAPGGEYAKGTEGPDRQYPGSDPDVVAQHLFEQRGVDIAVLH
MMAR_4724|M.marinum_M PDYEMDWYGAPGSEYAPNTEGPDRQYPGSDPKFVADELFSRRGVDVAVLH
MAV_0930|M.avium_104 PDYEMDWYGAPGSEYAPNTDGPDGQYPGSDPEFVAQELFSKRGVDVAVLH
*****:******.*** * *** *******...*..** ****:*:**
Mflv_2490|M.gilvum_PYR-GCK PMTRGIMPDRHLGTAIASAHNEMMVTRWLDHPEFGERFRGTLRVNPDDIA
Mvan_4164|M.vanbaalenii_PYR-1 PMTRGIMPDRHLGTALAAAHNEMMVTRWLDHPQLGEKFRGTLRVNPDDIA
MSMEG_4807|M.smegmatis_MC2_155 PMTRGIMPDRHLGTALANAHNEMMVTRWLDHERYGERFRGTIRVNPDDIA
TH_4618|M.thermoresistible__bu PMTRGIMPDRHLGTALAAAHNEMLVTRWLDHPEFGDRFRGTIRVNPDDIA
MMAR_4724|M.marinum_M PMGRGIMPDRHLGSALHAAHNEMMVSRWLEHDEFGDRFRGTIRVNPDDIA
MAV_0930|M.avium_104 PMGRGIMPDRHLGSALHAAHNEMMVSRWLDSPEFGEKFRGTIRVNPDDIA
** **********:*: *****:*:***: . *::****:********
Mflv_2490|M.gilvum_PYR-GCK GALREIDKYRDHPRIVQLGIPLQSREVYGKPQFWPLWEAAVDAGWPVAVH
Mvan_4164|M.vanbaalenii_PYR-1 GALREIDKYKSHPRIVQLGIPLQSRELYGKPQYWPLWEAAVDAGWPVAVH
MSMEG_4807|M.smegmatis_MC2_155 GALREIERFKDHPRVVQIGVPLQSRELYGKPQYWPLWEAASDAGLPVAVH
TH_4618|M.thermoresistible__bu GSLREIEKYKDHPRVVQLGIPLQSRELYGKPQFWPLWEAAVAANLPVAVH
MMAR_4724|M.marinum_M GAVREVAKWRAHPRVVQIGVPLQSRELYGKPQFWPLWEAAVEAGLPVAVH
MAV_0930|M.avium_104 GALRELERWRSHPRVVQLGIPLQSRELYGKPQFWPLWEAAADANLPVAVH
*::**: ::: ***:**:*:******:*****:******* *. *****
Mflv_2490|M.gilvum_PYR-GCK FEVGSGVALPPTPNGLTRTYEQYVGFTALNFLYHLMNMIAEGVFERMPDL
Mvan_4164|M.vanbaalenii_PYR-1 FEVGSGVQLPPTPSGLTRTYEQFVGFTALNFLYHLMNMIAEGVFERMPAL
MSMEG_4807|M.smegmatis_MC2_155 IEVGAGVQFAPTPSGKTRTYEQYLGFMALNYLYHLMNMIAEGVFERMPAL
TH_4618|M.thermoresistible__bu IEVGAGIAASPTPSGNTRTYEQYVGFMALNYLYHLMNMIAEGVFERMPTL
MMAR_4724|M.marinum_M IESGEGIGFPPTPSGHTRTYEQYVSFMALNYLYHLMNMIAEGVFERFAEL
MAV_0930|M.avium_104 IETGEGIGFPPTPSGHTQTYEQYVSFMALNYLYHLMNMIAEGVFERFPAL
:* * *: .***.* *:****::.* ***:***************:. *
Mflv_2490|M.gilvum_PYR-GCK KFVWADGAADLLTPFMWRMDCFGRPHLEQTPWAPRMPSDYLPGHVFFVQG
Mvan_4164|M.vanbaalenii_PYR-1 KFVWADGAADMLTPFIWRMDCFGRPHLEQTPWAPRIPSDYLPDHVYFVQG
MSMEG_4807|M.smegmatis_MC2_155 KFVWADGAADLLTPFIWRMDCFGRPHLEQTPWAPKMPSDYLPGHVYFVQG
TH_4618|M.thermoresistible__bu KFVWADGAADLLTPFIWRMDCFGRPHLEQTPWAPRMPSDYLPGHVYFVQG
MMAR_4724|M.marinum_M KFIWADGAADFVTPFIWRMDTFGRPHLEQTPWAPRIPSDYLPGHVYFIQG
MAV_0930|M.avium_104 KFVWADGAADFLTPFIWRMDTFGRPHLEQTPWAPRIPSDYIPGHVYFVQG
**:*******::***:**** *************::****:*.**:*:**
Mflv_2490|M.gilvum_PYR-GCK ALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQL----NELTVPGSYDP
Mvan_4164|M.vanbaalenii_PYR-1 ALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQL----NELSVPTAYTP
MSMEG_4807|M.smegmatis_MC2_155 ALDGPGDVEFAGEWFGFTGKENMVMFGSSYPHWQL----NEPEVPTAFTP
TH_4618|M.thermoresistible__bu FLDGPGDVDFAGEWFGFTGKENMVMFGSSYPHWQL----NELTIPGTFSA
MMAR_4724|M.marinum_M GLDGPGDVEFADEWLSFTGKEDMVMFGSSYPHWQCYDLRDVRNLPTALTA
MAV_0930|M.avium_104 SLDGPGDADFAAEWFGFTGKEDMVMFGSSYPHWQC---ADVHKLPPALSA
******.:** ** .****::***:******** : :* : .
Mflv_2490|M.gilvum_PYR-GCK EQRDKLCWRNAAQLYGIQS---PAISVPAAAQ
Mvan_4164|M.vanbaalenii_PYR-1 DQRDKLCWRNAAALYGIESPVIPAVSTTAAAQ
MSMEG_4807|M.smegmatis_MC2_155 EQRDKLLWRNAAELYGLQS---ALTSTAGAAR
TH_4618|M.thermoresistible__bu EQRDKLCWRNAAELYNIES---SAIPSAALAK
MMAR_4724|M.marinum_M DQREKLCWRNAAELYGIDI------SAELTSG
MAV_0930|M.avium_104 EQREKLCWRTAADLYGIDI------SVDLAAS
:**:** **.** **.:: . :