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M. gilvum PYR-GCK Mflv_2548 (-)

annotation: peptidase S9 prolyl oligopeptidase
coordinates: 2659327 - 2661261
length: 644

VRALSASATGPPVTTGADRAQSGTVAEQVRRIYGASMSPDATAFAHLVDDGGYPRAVQRFLRGWRASSSR
DVELPVEGPVTRVLHSADGHWLACQVAPEGGTRSQIWVVTTDPDDRAARRIDHWPSGVDGTAELIGWDGT
WVAAILTGEDGVGSSCLIDPSGGTTTVLDRRSGGRLVDSWAGASLVRVGPRGYRDLIMLRGLTETGLLPY
DPGSTTDTGVILDDHHPRRLRTGPDGELSELYHPAKIYGVNSTEGYVRALIRSENGAEHARLLEVTVSAE
GVTYQVVAERPGCELDEFTVSDDLSTVAILWNIHGASELQILEYADGTLYDPIPLPGMVAGELSISAGGS
MLALTVEGPSKPPTVELVDPRTREWELVDREPSSGPVSADPTLETVTARDGLTFTGWLFRPREGVETIGA
MLFLHGGPEGQGRPGYNEFFPALLDEGICVFLPNVRGSGGFGRSFMHADDRERRFAAIDDVADCVRFLVG
NGHAPAGKVACCGWSYGGYLTQAALAFHPDEFAAGISICGMSDLNSWYRSTEQWIAAAAYPKYGHPVSDQ
SLLEQLSPLPRADAISAPLLLVHGLNDTNVPPGESEQMWEALTALGREVELLTFEDDGHEIDKRENRAVL
RKTMCEWLTAAFAE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2548--100% (644)peptidase S9 prolyl oligopeptidase
M. gilvum PYR-GCKMflv_4393-1e-3032.77% (296) peptidase S9 prolyl oligopeptidase
M. gilvum PYR-GCKMflv_2627-1e-1326.83% (246) peptidase S9 prolyl oligopeptidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0466c-2e-1026.52% (230) peptidase
M. tuberculosis H37RvRv0457c-2e-1026.52% (230) peptidase
M. leprae Br4923MLBr_02226ptrB2e-0623.43% (175) protease II
M. abscessus ATCC 19977MAB_4725-3e-3232.89% (301) peptidase
M. marinum MMMAR_0779-1e-1326.96% (230) peptidase
M. avium 104MAV_0727-1e-0722.35% (358) protease 2
M. smegmatis MC2 155MSMEG_4719-0.077.18% (618) peptidase S9, prolyl oligopeptidase
M. thermoresistible (build 8)TH_4519-0.076.01% (621) PUTATIVE peptidase S9, prolyl oligopeptidase active site domain
M. ulcerans Agy99MUL_0498ptrB2e-0725.65% (230) protease II (oligopeptidase B), PtrB
M. vanbaalenii PYR-1Mvan_4095-0.089.19% (620) peptidase S9 prolyl oligopeptidase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2548|M.gilvum_PYR-GCK          ----------------MRALSASATGPPVTTGADRAQSGTVAEQVRRIYG
Mvan_4095|M.vanbaalenii_PYR-1       ----------------------------------------MAEQVRRIYG
MSMEG_4719|M.smegmatis_MC2_155      ----------------------------------------------MNYG
TH_4519|M.thermoresistible__bu      ----------------------------------------VAEQVRATYG
Mb0466c|M.bovis_AF2122/97           -----------MASMTFEP---APDGAD----PYLWLEDVTGAEALDWVR
Rv0457c|M.tuberculosis_H37Rv        --------------MTFEP---APDGAD----PYLWLEDVTGAEALDWVR
MMAR_0779|M.marinum_M               -----------MAPKAPEAPQ-APDAADTTTDPYLWLEDVTGEEALDWVR
MAV_0727|M.avium_104                MTETHLATS--VPPVAKRVDTRREHHGDVFVDPYEWLREKTDPDVIAHLE
MUL_0498|M.ulcerans_Agy99           MDRAGRMTDRTLPPVAKRVEIRREHHGDVFVDPYEWLRDKDSVEVIAHLE
MLBr_02226|M.leprae_Br4923          MTKTSRGTP--VPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLD
MAB_4725|M.abscessus_ATCC_1997      ------------------------------MGLPKLITVEEFFEPPVRTS
                                                                                      

Mflv_2548|M.gilvum_PYR-GCK          ASMSPDATAFAH-----------------LVDDGGYPRAVQR--FLRGWR
Mvan_4095|M.vanbaalenii_PYR-1       ASMSPDATAFAH-----------------LVDDGGYPRAVQR--FLRGWR
MSMEG_4719|M.smegmatis_MC2_155      ASLSPDATAFAH-----------------LVDDGGFPRAVQR--FLRGWR
TH_4519|M.thermoresistible__bu      ASLSPDATAFAH-----------------LVDDGGFPRAVQR--FLRGWR
Mb0466c|M.bovis_AF2122/97           ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW
Rv0457c|M.tuberculosis_H37Rv        ARNKPTTAAFC----DAEFERMRVEALEVLDTDARIPYVNRRGNYLYNFW
MMAR_0779|M.marinum_M               ARNEPTKAQFCGGESEDEFERMRTEALEVLDTDARIPYVRRRGDYLYDFW
MAV_0727|M.avium_104                AESDYADRMTAH---LAPLRQQIFDEIKARTKETDLSVPTRQGRWWYYAR
MUL_0498|M.ulcerans_Agy99           AENTYTDQTTAH---LEPLRQKIFDEIKARTKETDLSVPTRRGNWWYYAR
MLBr_02226|M.leprae_Br4923          AENDYVNQMTAH---LEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSR
MAB_4725|M.abscessus_ATCC_1997      ASISPDGTMIAY----------------------LAPRKNRLNVWVQGIG
                                    *         .                         .   :   :     

Mflv_2548|M.gilvum_PYR-GCK          ASSSRDVELPVEGPVTR----------VLHSADGHWLACQVAPEGGTRSQ
Mvan_4095|M.vanbaalenii_PYR-1       ASSSRDVELPVEGPVTR----------VMHSADGHWLACQVAPEGGSRSQ
MSMEG_4719|M.smegmatis_MC2_155      ASSSRDVELPVVGPVLR----------VLHSADGHWLACEVAPEGATRSQ
TH_4519|M.thermoresistible__bu      ASSSRDVELPVVGPVRR----------VLHSPDGGWLACEVAPDGSDRSQ
Mb0466c|M.bovis_AF2122/97           RDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRADDQ
Rv0457c|M.tuberculosis_H37Rv        RDAANPRGLWRRTTLDS----------YRTDSPGWDVLIDVDELGRADDQ
MMAR_0779|M.marinum_M               RDANNPRGLWRRTTLES----------YRTDAPEWDVLIDVDELGRTDNK
MAV_0727|M.avium_104                TYEGKQYRVQCRCPVADPDDWNPPNLDEDTDIPGEQIMLDSNVE--AEGH
MUL_0498|M.ulcerans_Agy99           TFEGRQYGVHCRCPAADPDDWNPPQFDEHTEIPGEQVLLDENEE--AEGH
MLBr_02226|M.leprae_Br4923          TFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAE--AEGH
MAB_4725|M.abscessus_ATCC_1997      STEARCVTHDETRSVTG----------FFWVDDPRWLLYVQDSGGDENWH
                                        .        .                      :            :

Mflv_2548|M.gilvum_PYR-GCK          IWVVTTDPDDRAARRIDHWP-SGVDGTAELIGWDGTWVAAILTG---EDG
Mvan_4095|M.vanbaalenii_PYR-1       IWVVTTDPDDRDARRIDRWP-SGVEGTAELISWDGTLVAAILTG---EDG
MSMEG_4719|M.smegmatis_MC2_155      IWVVTTDPDDRDARRIDSWP-DGTEGTAELIGWDGTKVAAILTG---DDG
TH_4519|M.thermoresistible__bu      IWVVTTDPDDRGAHRIDSWPPDAPEGAAELIAWDGNRIAAILTG---QDG
Mb0466c|M.bovis_AF2122/97           KWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPP
Rv0457c|M.tuberculosis_H37Rv        KWVWGGAGVIEPDYTRALIGLSPGGSDASIVREFDMLTREFVEDGFQLPP
MMAR_0779|M.marinum_M               KWVWAGADVIEPEFTRALISLSPGGSDAVIVREFDMVTREFVADGFELPE
MAV_0727|M.avium_104                EFFALGAATVSLDGNLLAYSVDTVGDERYTLRFKDLRTGELYPD--EIAD
MUL_0498|M.ulcerans_Agy99           DFFALGAASVSLDDNVLAYSVDVVGDERYTLRFKDLRTGQRYPD--EIAD
MLBr_02226|M.leprae_Br4923          AFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD--EIVG
MAB_4725|M.abscessus_ATCC_1997      LYRVDLSTPDATAVDLTPFPGARLLGLERPYGRSGKVYIQLNHR--RIDQ
                                     :                       .        .               

Mflv_2548|M.gilvum_PYR-GCK          VGSSCLIDPSGGTTTVLDRRSGGRLVDSWAG-ASLVRVGPRGYRDLIMLR
Mvan_4095|M.vanbaalenii_PYR-1       VGTSCLLDPSGTTVIVLDRRSGGRLVDAWGG-ASLVRVGPRGYRDLIMLR
MSMEG_4719|M.smegmatis_MC2_155      VGSSCLIDPGTGETTVLDRRSSGRLVDSWQG-ASLIRVGPRGYRELIMLW
TH_4519|M.thermoresistible__bu      VGSSCLIDPADGSTVVLDRRSGGRLVDAWAG-AALIRVGPRGYRELIMLH
Mb0466c|M.bovis_AF2122/97           AKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFE
Rv0457c|M.tuberculosis_H37Rv        AKSQITWEDPDTVLLGTDFGGDSLTTSGYPRVIKRWRRGKPLADAETIFE
MMAR_0779|M.marinum_M               AKSQVGWDDPDTILVGTDFGPDSMTESGYPRIVKRWRRGTPLSDAEMIFQ
MAV_0727|M.avium_104                IAAGATWAADNRTVYYLTLD-----AAHRPDKVWRYRAGSGEA-PELVYH
MUL_0498|M.ulcerans_Agy99           IGAGATWAADHRTVYYITVD-----AAWRPDTVWRYRLGSPGS-SERVYH
MLBr_02226|M.leprae_Br4923          IGAGATWAADNRTVYYLTLD-----ESRRPDTVWRCRLGSGQP-SEQVYH
MAB_4725|M.abscessus_ATCC_1997      IDLYELDIASGELTMLAENPGGVMAWFCGPNHEVFAQSLTPGGDIEFSRY
                                                                        :             

Mflv_2548|M.gilvum_PYR-GCK          GLTETGLLPYDPGSTTDTGVILDDHHP----RRLRTGPDGELSELYHPAK
Mvan_4095|M.vanbaalenii_PYR-1       ALTETALLPYDPGSTTDTGIILDDHSP----RRLRSGPEGETTDLYYPVK
MSMEG_4719|M.smegmatis_MC2_155      GQREIALLPYDPGSTTDYGVILDDHSP----RRVRSGLDGETVTLMEPHK
TH_4519|M.thermoresistible__bu      GNTEMALLPSDPGSTTDFGVILDDHSA----RRLRRGPDGELTKLYQPAK
Mb0466c|M.bovis_AF2122/97           GAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTD
Rv0457c|M.tuberculosis_H37Rv        GAGTDVRVNASADRTPGFERTLLGRALDFWNEEVYELRGSELIRIEAPTD
MMAR_0779|M.marinum_M               GAHTDVSAGGSTDRTPGFERTFVSRSLDFWNRQRYELRGTELIPLDVPTD
MAV_0727|M.avium_104                EADEKFWLGVGLTRSEAYVMIASGSSITSEFRYADAADPHAQFTVVLPRR
MUL_0498|M.ulcerans_Agy99           EPDERFWLGVGRTRSNKYIFIAAGSSVTSEMRYADSADPSAQFTIVLPRR
MLBr_02226|M.leprae_Br4923          EADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRR
MAB_4725|M.abscessus_ATCC_1997      ESGALRPLCVYDGADYPVGMNPTQMTPDGSGMWLGSSRDTDRTRLVR---
                                                                                :     

Mflv_2548|M.gilvum_PYR-GCK          IYGVN--------STEGYVR-------ALIRSENGAEHARLLEVTVSAEG
Mvan_4095|M.vanbaalenii_PYR-1       DYGLD--------STEGYVR-------ALIRSENGAQHARLLEVTVTADG
MSMEG_4719|M.smegmatis_MC2_155      YFQADGESHTTEGTTEGYVR-------ALIRSENGASHARLLEVTVTADG
TH_4519|M.thermoresistible__bu      RYPRE--------STEGYVR-------ALIRSDNGAGYARLLEVTTTADG
Mb0466c|M.bovis_AF2122/97           AS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSA
Rv0457c|M.tuberculosis_H37Rv        AS-VSIHRDWLLIELRTDWT------VATTRYTAGSLLAAEYDEFLAGSA
MMAR_0779|M.marinum_M               ASSMSVHREWLLIELRTDWSPKAGADDAAKTYRAGSLLAANYDDFLSGTS
MAV_0727|M.avium_104                DG-VEYSVEHA---VVGGQD------RFLILHNDGAVNFTLTEAPVSDPT
MUL_0498|M.ulcerans_Agy99           EG-VEYSVEHA---VIGGQD------RFLILHNDGAVNFTLVEAPVDDPT
MLBr_02226|M.leprae_Br4923          DG-IEYSVEHAPSGLVGGQD------RFLILHNDGAVNFTLVESPVSNPE
MAB_4725|M.abscessus_ATCC_1997      --------------------------LDLATGAESTIDSHPAYDLAAALG
                                                                      .:              

Mflv_2548|M.gilvum_PYR-GCK          VTYQVVAERPGCELDEFTVSDDLSTVAILWNIHGASELQILEYADGTLYD
Mvan_4095|M.vanbaalenii_PYR-1       VSYQVVAERPGYELDEFTVSDDLSTVAMLWNLHGASELQILEYADQTLHD
MSMEG_4719|M.smegmatis_MC2_155      VSYHVVAERPGYELDEFVVSDDLSTVAMLWNVDGRSELQILEYADETLSE
TH_4519|M.thermoresistible__bu      VAYQVVAERPGHDLDEFVVSDDLSTVALLWNIDGASELQILQYADNTLSE
Mb0466c|M.bovis_AF2122/97           ELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRRE
Rv0457c|M.tuberculosis_H37Rv        ELQVVFEPDEHTALYQYAWTRDRLLIVTLADVASRVEIATP---GSWRRE
MMAR_0779|M.marinum_M               DLHVVFEPDEHTCLYHYAWVRDRLLMVSLADVASQVEIVTP---GSWRRE
MAV_0727|M.avium_104                RQRTLIPHRDDVRLDAVDAFEGHLVISYRRAALPRLQLWRIDADGTYARP
MUL_0498|M.ulcerans_Agy99           RQRTLIPHREDVRLDGVDAFAAHLVVSYRIEALPRIQLWPLTADGDYGEV
MLBr_02226|M.leprae_Br4923          QQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEP
MAB_4725|M.abscessus_ATCC_1997      LPPTLIRHRKSGELLAARYLGARQEIRVLDPDFG-----------PVLEK
                                        :.       *           :                        

Mflv_2548|M.gilvum_PYR-GCK          PIPLPGMVAGELSISAGG----SMLALTVEGPSKPPTVELVDPRTREWEL
Mvan_4095|M.vanbaalenii_PYR-1       PIPLPGMVAGELSISAGG----TMLAMTVEGPSKPPTVELVDPRTREWEL
MSMEG_4719|M.smegmatis_MC2_155      PIPLPGMVASQLSISAGG----SMVAMTVQGPSLPPTVELVDPRTREWER
TH_4519|M.thermoresistible__bu      PIPLPGMVAGELSISAGG----SMVAMTVESPWLPPTVELVDPRTRQWEL
Mb0466c|M.bovis_AF2122/97           PLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRL
Rv0457c|M.tuberculosis_H37Rv        PLSGIPAATNTVIVSADS--HGDEFFLDSSGFDTPSRLMRGTD---DGRL
MMAR_0779|M.marinum_M               PIAGIPASTNTVIVAADD--TGDEFFVDSSGFDAPSRLLRGTAGSATTQL
MAV_0727|M.avium_104                EEISFDSELMSAGLAGNPNWSAPRLRIRAGSLVIPARVYDIDFVTGERTL
MUL_0498|M.ulcerans_Agy99           EDVVFDSELMSAGLGANPNWDCPKLRVGAGSFITPVRIYDIDFCTGERTL
MLBr_02226|M.leprae_Br4923          EEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTL
MAB_4725|M.abscessus_ATCC_1997      LQELSDGDLAEVSSDEDG----RRWVVSFTHDRDPGVTYFYDHATGESHQ
                                                    .         :       *               

Mflv_2548|M.gilvum_PYR-GCK          VDREPSSGPVSAD---PTLETVTARDGLTFTGWLFRPREGV-ETIGAMLF
Mvan_4095|M.vanbaalenii_PYR-1       VDREPSCGPVSDD---PTLETIIARDGLTFSGWLFRPPEGV-ETIGAMLF
MSMEG_4719|M.smegmatis_MC2_155      IDREPSGGPVTGT---PTLEMITARDGLELNSWLYWPHT---EPIGAMLF
TH_4519|M.thermoresistible__bu      IDREPSTGPVTGT---PTLERLTARDGLELTGWLYRPPTGV-QPVGAMIF
Mb0466c|M.bovis_AF2122/97           AEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDAD-NPGPTLLN
Rv0457c|M.tuberculosis_H37Rv        AEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDAD-NPGPTLLN
MMAR_0779|M.marinum_M               EQIKSAPTFFDAQNISVSQHFATSEDGTSIPYFLVRPTGSD-GPGPTLLY
MAV_0727|M.avium_104                LREQPVLGDYRPADYVERRDWAVADDGTRVPVSIVHRADIE-FPAPALIY
MUL_0498|M.ulcerans_Agy99           LREQPVLGGYRREDYVERRDWAHAEDGTRIPISIVYRGGIQ-LPAPAMIY
MLBr_02226|M.leprae_Br4923          LREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIR-FPAPAVLY
MAB_4725|M.abscessus_ATCC_1997      LFR-PYPHLDPADLAPVVPVTITARDGLTLNSYLTLPVGTEPEGLPLVLV
                                        .                  : **  .   :             :: 

Mflv_2548|M.gilvum_PYR-GCK          LHGGPEGQGRPGYN-EFFPALLDEGICVFLPNVRGSGGFGRSFMHADDRE
Mvan_4095|M.vanbaalenii_PYR-1       LHGGPEGQGRPGYN-EFFPALLDEGICVFLPNVRGSGGFGRAFMHADDRE
MSMEG_4719|M.smegmatis_MC2_155      LHGGPEGQARPEYN-EFYPQLLEAGIAVLTPNVRGSGGFGRAFMHADDKE
TH_4519|M.thermoresistible__bu      LHGGPEGQSRPGYN-EYFPPLLDRGITVFTPNVRGSGGFGRSFVHADDKE
Mb0466c|M.bovis_AF2122/97           GYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMRE
Rv0457c|M.tuberculosis_H37Rv        GYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMRE
MMAR_0779|M.marinum_M               GYGGFETSNTPGYSGVMGRLWLARGGTYVLANIRGGGEYGPGWHTQAMRE
MAV_0727|M.avium_104                GYGAYEICIDPSFS-IARLSLLDRGMVFAIAHVRGGGEMGRLWYEHGKLL
MUL_0498|M.ulcerans_Agy99           AYGAYEICEDPRFS-IARLSLLDRGMVFVIAHVRGGGEMGRLWYEHGKLL
MLBr_02226|M.leprae_Br4923          GYGAYEICVDPSFS-IPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLL
MAB_4725|M.abscessus_ATCC_1997      VHGGPWHRDSWGFD-PTVQLLANRGYAVLQVNFRGSTGYGKAFTKAAIGE
                                     :*.        :.          *      :.**.   *  :       

Mflv_2548|M.gilvum_PYR-GCK          RRFAAIDDVADCVRFLVGNGHAPAGKVACCGWSYGGYLTQAALAFHPDEF
Mvan_4095|M.vanbaalenii_PYR-1       RRFAAIDDVADAARFLVGNGHAPAGRVACCGWSYGGYLTQAALTFHPDEF
MSMEG_4719|M.smegmatis_MC2_155      RRFAAIDDVADCVQYLVDKGLAPADKIACTGWSYGGYLTLAALTFHPELF
TH_4519|M.thermoresistible__bu      NRFRAIDDVADCVHYLVRNGLAPADRIACAGWSYGGYLTQAALAFHPDLF
Mb0466c|M.bovis_AF2122/97           GRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKF
Rv0457c|M.tuberculosis_H37Rv        GRDKVAQDFAAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKF
MMAR_0779|M.marinum_M               GRHKVAEDFVAVADDLVRRGITTVDQLGAQGGSNGGLLMGIMVTKYPEKF
MAV_0727|M.avium_104                EKKNTFTDFVSAARHLVESNVTRPDRLVALGGSAGGLLVGAVANLAPELF
MUL_0498|M.ulcerans_Agy99           QKKNTFTDFIAVAEHLVESGLTQPERLVALGGSAGGLLMGAVANMAPELF
MLBr_02226|M.leprae_Br4923          EKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLF
MAB_4725|M.abscessus_ATCC_1997      FAGKMHDDLIDAVDWAVEQGYADPGRIAIFGGSYGGYSALVGVTFTPDVF
                                           *.   .   *  . :   .:   * * **          *: *

Mflv_2548|M.gilvum_PYR-GCK          AAGISICGMSDLNSWYRSTEQWIAAAAYPKYGHPVSD----QSLLEQLSP
Mvan_4095|M.vanbaalenii_PYR-1       AAGISICGMSDLNSWYRNTEQWIAAAAYPKYGHPVSD----QDLLERLSP
MSMEG_4719|M.smegmatis_MC2_155      AAGISICGMSDLNTFYRNTEPWIAAAAYPKYGHPVAD----RDLLEKLSP
TH_4519|M.thermoresistible__bu      AAGISVCGMSDLTTWYQTTEPWIAQSSYTEYGHPVAD----RDLLERLSP
Mb0466c|M.bovis_AF2122/97           GALVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD-----WKFISEYSP
Rv0457c|M.tuberculosis_H37Rv        GALVCDVPLLDMKRYHLLLAGASWMAEYGDPDNPDD-----WKFISEYSP
MMAR_0779|M.marinum_M               GALVCNVPLLDMKRYHLLLAGASWVAEYGDPDNPDD-----WAFISEYSP
MAV_0727|M.avium_104                AGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLADKDV-YFYMKSYSP
MUL_0498|M.ulcerans_Agy99           AGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLSDSEV-YAYMKSYSP
MLBr_02226|M.leprae_Br4923          TGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDF-YSYIKSYSP
MAB_4725|M.abscessus_ATCC_1997      AAAVDYVGISNLANFMRTLPPFVRPNLANNWYRYVGDPAVPEQEADMLAR
                                     . :    : :                  .  .            .  : 

Mflv_2548|M.gilvum_PYR-GCK          LP--RADAISAPLLLVHGLNDTNVPPGESEQMWEALTAL---GREVELLT
Mvan_4095|M.vanbaalenii_PYR-1       LP--RADKVTAPLLLVHGLNDTNVPPGESQQMYDALTEL---GRRVELLT
MSMEG_4719|M.smegmatis_MC2_155      LP--RAHALTAPLLLVHGANDTNVPPSESLQMYDALHDL---GRPVELLM
TH_4519|M.thermoresistible__bu      LT--HAAAVTAPLLLVHGASDTNVPPSESIQMHTALERL---GRPVKLLM
Mb0466c|M.bovis_AF2122/97           YQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYE
Rv0457c|M.tuberculosis_H37Rv        YQNISANRKYPPVLMTTSTRDDRVHPGHARKMTAALQAA---GHPVWYYE
MMAR_0779|M.marinum_M               YQNISADRTYPPILITTSTRDDRVHPGHARKMTAALQAS---GHRVWYYE
MAV_0727|M.avium_104                YENVDA-RRYPAIMAMTSLNDTRVYYVEPAKWVAALRHANPAGGPFLLKT
MUL_0498|M.ulcerans_Agy99           YENVAD-RRYPAILAMTSLNDTRVYFVEPAKWVAALRHANGDGNQVLLKT
MLBr_02226|M.leprae_Br4923          YENVEA-KQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKT
MAB_4725|M.abscessus_ATCC_1997      SPISRVDRIRTPLLVAQGANDVRVVQAESDNIVAALRAR---GVEVEYMV
                                              ..::   .  * .*   .. :   **      *  .    

Mflv_2548|M.gilvum_PYR-GCK          FEDDGHEIDKRENRAVLRKTMCEWLTAAFAE-------------------
Mvan_4095|M.vanbaalenii_PYR-1       FEDDGHEIDKRENRAVLRKAMTAWLVEAFAD-------------------
MSMEG_4719|M.smegmatis_MC2_155      FADDGHEIIKRENRAVLVDAMERWLVKAFTA-------------------
TH_4519|M.thermoresistible__bu      FDDDGHEIVRRENRATLVEAMSHWLMSAFAERRREAS-------------
Mb0466c|M.bovis_AF2122/97           NIEGGHAGAADNAQIAFKSALSFAFLWRMLAG------------------
Rv0457c|M.tuberculosis_H37Rv        NIEGGHAGAADNAQIAFKSALSFAFLWRMLAG------------------
MMAR_0779|M.marinum_M               NIEGGHGGAADNEQLAFKSALSYSFLWRMLGSRK----------------
MAV_0727|M.avium_104                QMNAGHGGVSGRYKAWEETAYQYAWLLAAAEGDRYGGG-QKDDLHPDPQG
MUL_0498|M.ulcerans_Agy99           QMNAGHGGISGRYERWKETAFQSAWLLAAAGCDDSGGG------------
MLBr_02226|M.leprae_Br4923          QMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG
MAB_4725|M.abscessus_ATCC_1997      KADEGHGFLNPENQIDLHRATERFLAQHVGGRQVS---------------
                                        **     . .     :