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MDGALLVLIVLVVAAIGLAVYATSKSSQKRNAASLADAKADARRTIERLGGQVFALTGIDDASKQALADA SERYTAASSQIDQATTARQAELAKESAMEGLYYVRAARLALGMDPGPELETLAGQRTAGTVTEDRRVQFE GREIEASPTPSQRTPNYYPGGRVAGRPVPAGWYSEPWWKPALVAGAWGLGSALLFSSLFSGMAGVGYDAQ AFESGYGDGFQDGLDQGQLEGGDAGGGDWGGGDAGGGDWGGGWDSGGGGDWGGGDFGGFEF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4049 | - | - | 100% (271) | hypothetical protein Mvan_4049 |
M. vanbaalenii PYR-1 | Mvan_1569 | - | 6e-06 | 39.56% (91) | hypothetical protein Mvan_1569 |
M. vanbaalenii PYR-1 | Mvan_2459 | - | 4e-05 | 36.36% (77) | PE_PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1116 | PE_PGRS21 | 4e-08 | 41.76% (91) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_2584 | - | 1e-133 | 87.08% (271) | hypothetical protein Mflv_2584 |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 2e-07 | 38.37% (86) | PE-PGRS family protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1577c | - | 1e-102 | 69.20% (276) | hypothetical protein MAB_1577c |
M. marinum M | MMAR_0601 | - | 3e-09 | 40.00% (130) | hypothetical protein MMAR_0601 |
M. avium 104 | MAV_3950 | - | 2e-13 | 27.44% (277) | hypothetical protein MAV_3950 |
M. smegmatis MC2 155 | MSMEG_4681 | - | 1e-116 | 75.55% (274) | hypothetical protein MSMEG_4681 |
M. thermoresistible (build 8) | TH_0349 | - | 1e-102 | 71.10% (263) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_3672 | - | 3e-08 | 40.45% (89) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_4049|M.vanbaalenii_PYR-1 -----------MDGALLVLIVLVVAAIGLAVYATSKSSQKRNAASLADAK Mflv_2584|M.gilvum_PYR-GCK -----------MNGVLLVLIVLVVAAIGIAVYASSKASGNRAAASLADAK MSMEG_4681|M.smegmatis_MC2_155 -----------MNGVLLLLIVLVIGAIAFAVYSSSRATGRRTAESLADAK TH_0349|M.thermoresistible__bu LGRRVVGRLVGMNGVLLLLVVLVLAAIVFAVYTASKSAGERNAMALADAK MAB_1577c|M.abscessus_ATCC_199 --------------MEIILGLLLLGVIVGGAIIYTQGSTRRRGEQLEDAK Rv3508|M.tuberculosis_H37Rv ------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGA MUL_3672|M.ulcerans_Agy99 ------MAYVIADLEAMAAAAADLAGVNSAIAAANGIAAVPTTAVQACAG Mb1116|M.bovis_AF2122/97 ------MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVLAAGA MMAR_0601|M.marinum_M ----------MFSSAATVVGCKTLGGVLDVVLGVSMAAADVRMALVEGED MAV_3950|M.avium_104 -----------MTSRFAGLALAPVAIALAMLFAPFAGADDYTDQLVARFD : : Mvan_4049|M.vanbaalenii_PYR-1 ADARRTIERLGG--------QVFALTGIDDASKQALADASERYTAASSQ- Mflv_2584|M.gilvum_PYR-GCK ADARRVIERLGG--------QVFALTGSDDASKQALADASERYTAASSQ- MSMEG_4681|M.smegmatis_MC2_155 ADARRVIERLGG--------QVLNLSGTDDASKQALADASERYTAAASQ- TH_0349|M.thermoresistible__bu AEARRLIERLGG--------QVLNLTGTDDASRQALADASERYTAAASQ- MAB_1577c|M.abscessus_ATCC_199 AEARRLTERLGG--------QVLGLSGTDDASRQALADASERYTAASSA- Rv3508|M.tuberculosis_H37Rv DEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA- MUL_3672|M.ulcerans_Agy99 DQVSAAVAALFAAHAQGYQSISTQMSAMHDQLVQTLSASSASYAGAEAS- Mb1116|M.bovis_AF2122/97 DEVSAAIASLFGAHGQAYQAVSAQMSAFHAQFMQALTGAGGAYAAAEAVN MMAR_0601|M.marinum_M GDGVIVEEDSFDLD------RNPVTSSASDQVVAAILGTREGAADAGLR- MAV_3950|M.avium_104 SQTHVVADPGARPPLQNPDGLNRQILAGPWRWSSGPPIWVAAVAPAQSG- : . : * Mvan_4049|M.vanbaalenii_PYR-1 -----------IDQATTARQAELAKESAMEGLYYVRAARLA--------- Mflv_2584|M.gilvum_PYR-GCK -----------IDQATTARQAELAKESAMEGLYYVRAARTA--------- MSMEG_4681|M.smegmatis_MC2_155 -----------IDQATTVKQAALAKESAIEGLYYVRAARTA--------- TH_0349|M.thermoresistible__bu -----------IEQATSVKQAMLAKESALEGLYYVRAARLA--------- MAB_1577c|M.abscessus_ATCC_199 -----------IEQARTPSQAALAKESAIEGLYYVRAARLA--------- Rv3508|M.tuberculosis_H37Rv -----AAEQIVLGVINAPTQALLGRPLIGDGANATTPGGAGGAGGLLFGN MUL_3672|M.ulcerans_Agy99 -----NAAQASLDLINAPTQALLGRPLIGNGADGATVGRIG--------- Mb1116|M.bovis_AF2122/97 VSAAQSVEQDLLAAINARFERIFGRPLIGDGANGG-PGQDG--------- MMAR_0601|M.marinum_M -----------LSSIGVTWTDPVQAAALRDALAWHKVENVM--------- MAV_3950|M.avium_104 -----------VTTADSIHEAMLRRDAQFSGVILVIDSRGYHVR------ : . .. Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGAGAAGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGV MUL_3672|M.ulcerans_Agy99 -------------------------TPGGAGG------------------ Mb1116|M.bovis_AF2122/97 ----------------------------GPGG------------------ MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLF MUL_3672|M.ulcerans_Agy99 -----------------------------------------------LLY Mb1116|M.bovis_AF2122/97 -----------------------------------------------LLY MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGA MUL_3672|M.ulcerans_Agy99 GNGGRG-------------------------------------------- Mb1116|M.bovis_AF2122/97 GNGGNG-------------------------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGA MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 ------LGMDPGPE------------------------------------ Mflv_2584|M.gilvum_PYR-GCK ------MGMDPGPE------------------------------------ MSMEG_4681|M.smegmatis_MC2_155 ------MGMDPGPE------------------------------------ TH_0349|M.thermoresistible__bu ------MGMDPGPE------------------------------------ MAB_1577c|M.abscessus_ATCC_199 ------MGMDPGPE------------------------------------ Rv3508|M.tuberculosis_H37Rv GGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGTG MUL_3672|M.ulcerans_Agy99 -GDSTLAGVSGGGG------------------------------------ Mb1116|M.bovis_AF2122/97 -GTSTTVGMAGGNG------------------------------------ MMAR_0601|M.marinum_M --------LVSGFL------------------------------------ MAV_3950|M.avium_104 ---AYHVPKVVADN------------------------------------ Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GQGGAGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQGGNAIAGGINGSG MUL_3672|M.ulcerans_Agy99 -------------------------GYAG----------------LIGNG Mb1116|M.bovis_AF2122/97 -------------------------GAAG----------------LIGNG MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -LETLAGQRTAGTVTEDR-------------------------------- Mflv_2584|M.gilvum_PYR-GCK -LESLTGQKSAGTVTEDR-------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -LETLAGQKSAGAVTEDR-------------------------------- TH_0349|M.thermoresistible__bu -LEPLAGQRVAGAVTEER-------------------------------- MAB_1577c|M.abscessus_ATCC_199 -LPSTAGQSRAGAVSEER-------------------------------- Rv3508|M.tuberculosis_H37Rv GAGGTGGQGGAGGMGGSGADNASGIGADGGAGGTGGNAGAGGAGGAAGTG MUL_3672|M.ulcerans_Agy99 GAGGTGGNGGSGGLGGN--------------------------------- Mb1116|M.bovis_AF2122/97 GFGGGGGPGAAGGNGGAG-------------------------------- MMAR_0601|M.marinum_M -AAAALGQAVGGALSYAR-------------------------------- MAV_3950|M.avium_104 -VDEFMNQSAQDHRNDPYG------------------------------- . . Mvan_4049|M.vanbaalenii_PYR-1 ----------RVQFEGREIEASPTPSQRTPN------------------- Mflv_2584|M.gilvum_PYR-GCK ----------RVNFEGREIEASPAPSPRTPN------------------- MSMEG_4681|M.smegmatis_MC2_155 ----------RINFEGREIEASPAPSPRTPN------------------- TH_0349|M.thermoresistible__bu ----------RIEFEGREIAASPTPSERTPN------------------- MAB_1577c|M.abscessus_ATCC_199 ----------RINFEGREIEASPQPSGRTPN------------------- Rv3508|M.tuberculosis_H37Rv GTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATATGATGGTGFSGGAGG MUL_3672|M.ulcerans_Agy99 -----------AWLLGSGGTGGTGGAGVS--------------------- Mb1116|M.bovis_AF2122/97 -----------GWLFGNGGAGGAGGLGVAPG------------------- MMAR_0601|M.marinum_M ----------TAVLFIEPDTATLAVVDTADG------------------- MAV_3950|M.avium_104 ---------AASEFVGKLSGVSVPTRAPVSTSPLVQHQ------------ : Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGG MUL_3672|M.ulcerans_Agy99 ---------------------------------------SGFGGTGGNGG Mb1116|M.bovis_AF2122/97 -------------------------------------VPGGAGGAGGAGG MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 ------------------YYPGGRVAGRPVP--AG--------------- Mflv_2584|M.gilvum_PYR-GCK ------------------YYPGGRVAGRPVP--AG--------------- MSMEG_4681|M.smegmatis_MC2_155 ------------------YYPGGRVAGRPVP--AG--------------- TH_0349|M.thermoresistible__bu ------------------YFPGGQVAGRPVP--AG--------------- MAB_1577c|M.abscessus_ATCC_199 ------------------YYPGGTVAGRPVP--AG--------------- Rv3508|M.tuberculosis_H37Rv KGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGG MUL_3672|M.ulcerans_Agy99 LG--------------GLLYGSGGAGGTGGAGAAG--------------- Mb1116|M.bovis_AF2122/97 VGG------------PAGLWGHGGAGGAGGAGVAG--------------- MMAR_0601|M.marinum_M ------------SVSEVCQQLLAEDDDAAVAEVVA--------------- MAV_3950|M.avium_104 -------------RDDWAWLKAAFVIAGITLATAG--------------- . .. Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAG MUL_3672|M.ulcerans_Agy99 ----------------------------------AVLGGMGGLG------ Mb1116|M.bovis_AF2122/97 ---------------------------------AGGFEGTIGAG------ MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKG MUL_3672|M.ulcerans_Agy99 -------------GDARLFG------------------------------ Mb1116|M.bovis_AF2122/97 -------------GAGGVGG------------------------------ MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 ---WYSEPWWKP-------------------------------------- Mflv_2584|M.gilvum_PYR-GCK ---WYSEPWWKP-------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 ---WYSEPWWKP-------------------------------------- TH_0349|M.thermoresistible__bu ---WYSEPWWKP-------------------------------------- MAB_1577c|M.abscessus_ATCC_199 ---WYSEPWWKP-------------------------------------- Rv3508|M.tuberculosis_H37Rv GTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGAT MUL_3672|M.ulcerans_Agy99 -TGGAGGTGGDN-------------------------------------- Mb1116|M.bovis_AF2122/97 -AGGVGGAGGAG-------------------------------------- MMAR_0601|M.marinum_M ---MVAAAESLP-------------------------------------- MAV_3950|M.avium_104 -LIWFAVSRNRK-------------------------------------- . . Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGING MUL_3672|M.ulcerans_Agy99 ----------------------SLGLT----GQGGQG------------- Mb1116|M.bovis_AF2122/97 ------------------------GWLY---GDAGAG------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 ------------------------------ALVAGAWGLG---------- Mflv_2584|M.gilvum_PYR-GCK ------------------------------ALVAGAWGLG---------- MSMEG_4681|M.smegmatis_MC2_155 ------------------------------ALVAGAWGLG---------- TH_0349|M.thermoresistible__bu ------------------------------ALVAGAWGLG---------- MAB_1577c|M.abscessus_ATCC_199 ------------------------------ALVAGAWGVG---------- Rv3508|M.tuberculosis_H37Rv AGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAK MUL_3672|M.ulcerans_Agy99 ----------------------------GDAGAGGASGYG---------- Mb1116|M.bovis_AF2122/97 ----------------------------GDGGVGGAGGTG---------- MMAR_0601|M.marinum_M ------------------------------ARPDGVYVVG---------- MAV_3950|M.avium_104 -----------------HRKDIENREQIKQELITAASNVG---------- .. * Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSI MUL_3672|M.ulcerans_Agy99 ---------IGNGGAGGAAGDG---------------------------- Mb1116|M.bovis_AF2122/97 ----------GLGNRGGAGGAG---------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------S Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------S MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------S TH_0349|M.thermoresistible__bu -------------------------------------------------S MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------S Rv3508|M.tuberculosis_H37Rv NANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGA MUL_3672|M.ulcerans_Agy99 ------------------GGAGSLGTGGNGGSGG--------------RA Mb1116|M.bovis_AF2122/97 ------------------------GAGGVGGAGG---------------A MMAR_0601|M.marinum_M ----------------------------------------------TGVD MAV_3950|M.avium_104 -----------------------------------------------DLD Mvan_4049|M.vanbaalenii_PYR-1 ALLFSSLFSGMAG---------------------VGYDAQAFESGYG--- Mflv_2584|M.gilvum_PYR-GCK ALLFSTMFSGMAG---------------------VGYDAQAFENGYG--- MSMEG_4681|M.smegmatis_MC2_155 VLLFDALFSGMHG---------------------VDYGAQGFEAGYG--- TH_0349|M.thermoresistible__bu MMLFNMMFAGMAG---------------------TAY-EQGFDAGLA--- MAB_1577c|M.abscessus_ATCC_199 ALLFNSLFSGMHG---------------------VGYGAQGFESGFG--- Rv3508|M.tuberculosis_H37Rv AGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN MUL_3672|M.ulcerans_Agy99 ALLYGVGRDGGAGGAGGD-----------------GVGSAGGSGGLG--- Mb1116|M.bovis_AF2122/97 AGLWGGGGAGGVGGTGGG----------------AGLGAQSVTFSSS--- MMAR_0601|M.marinum_M VAMIKPALDAATS--------------------LTVSVSEEQEMALAR-- MAV_3950|M.avium_104 NEVLTDGNTDVSAES-------------------LKANASLHDARKAYE- . . Mvan_4049|M.vanbaalenii_PYR-1 -------------------------DGFQDGLDQGQ---LEGGDAGG--- Mflv_2584|M.gilvum_PYR-GCK -------------------------DGFQDGLDQGQ---LDGG------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------DGYADGLAAGQDGGFDGGADAG--- TH_0349|M.thermoresistible__bu -------------------------QGMAG----------DTG------- MAB_1577c|M.abscessus_ATCC_199 -------------------------QGYSDGYDAGLNAGQDSGADQGGWD Rv3508|M.tuberculosis_H37Rv GAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTA MUL_3672|M.ulcerans_Agy99 -----------------GAAGLVDVGGDGGAGGAGGGAGGDGGAGAYLIG Mb1116|M.bovis_AF2122/97 ------------------LSGLS--GGDGGAGGAGG-AGGAGGTGGWLYG MMAR_0601|M.marinum_M -------------------------GAALACGNAPLFAATTAALAYAQDL MAV_3950|M.avium_104 -------------------------KGDYGAARAHLRVVESTVAKANRKL . Mvan_4049|M.vanbaalenii_PYR-1 -----------GDWGGGDAGGGDWGG------------------------ Mflv_2584|M.gilvum_PYR-GCK -----------GDWGG-DAGGGDWDS------------------------ MSMEG_4681|M.smegmatis_MC2_155 -----------GDWGG-DTAG-DWG------------------------- TH_0349|M.thermoresistible__bu -----------GDFGGSDFGG----------------------------- MAB_1577c|M.abscessus_ATCC_199 QGSGADQGGGWDQGGGWDSGGSGWD------------------------- Rv3508|M.tuberculosis_H37Rv KAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTS MUL_3672|M.ulcerans_Agy99 DGGDGGAGGHGGDGGAGGDGNAG--------------------------- Mb1116|M.bovis_AF2122/97 GGGAAGSGGDGGTGGQGGAGGAG--------------------------- MMAR_0601|M.marinum_M NDPDPLGESDLGDELSPDQEPAGRRS------------------------ MAV_3950|M.avium_104 HPGQREPEGAAADSSVPAPERKQASVR----------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------GWDSGGGG-DWGG------ Mflv_2584|M.gilvum_PYR-GCK -------------------------------GGDWGGG--DFGG------ MSMEG_4681|M.smegmatis_MC2_155 -------------------------------GMDTGGGWGDFGGD----- TH_0349|M.thermoresistible__bu -----------------------------------DGGGLDFGG------ MAB_1577c|M.abscessus_ATCC_199 -------------------------------GGGWDGGGGDFGG------ Rv3508|M.tuberculosis_H37Rv INANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGG MUL_3672|M.ulcerans_Agy99 ---------------------------SLAGGTGGNGGDAKVIG------ Mb1116|M.bovis_AF2122/97 -------------------------VFSLFGSGGGPGGNGGVGG------ MMAR_0601|M.marinum_M -------------------------------GLLIGSGLAVVAT------ MAV_3950|M.avium_104 ------------------------------TTDPETGQTVTISN------ . Mvan_4049|M.vanbaalenii_PYR-1 ----------GDFGGFEF-------------------------------- Mflv_2584|M.gilvum_PYR-GCK ----------GDFGGFDF-------------------------------- MSMEG_4681|M.smegmatis_MC2_155 ---------FGDFGGF---------------------------------- TH_0349|M.thermoresistible__bu ---------FGDFGGF---------------------------------- MAB_1577c|M.abscessus_ATCC_199 -----------DFGDF---------------------------------- Rv3508|M.tuberculosis_H37Rv AAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGI MUL_3672|M.ulcerans_Agy99 ---------NGGNGGDGG----------VRFGGG---------------- Mb1116|M.bovis_AF2122/97 ---------VGGVGGAGG--------RAGLFGVG---------------- MMAR_0601|M.marinum_M ----------AAVVALEVALAIDIRPTVALQPRP---------------- MAV_3950|M.avium_104 ----------ADYRTTAQP------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv NGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPG MUL_3672|M.ulcerans_Agy99 --ANGSGGTGGAAG------LLGSP----------GSDGTTV-------- Mb1116|M.bovis_AF2122/97 -GLGGAGGDAGDSGEGG----FGGP----------GLAGGLFGN------ MMAR_0601|M.marinum_M ----NENHLVAPPPQAAPPPQVAAPEPKIELARPRVAPRAAS-------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv DGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGH MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 --------------PGNGGVGGIG-------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGT MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -------------------GDAAAGGAGGAGGNGG--------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQ MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 ---------------------------------------WLFGNGGAGGS MMAR_0601|M.marinum_M ----------------------------------------------PQLP MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGD MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 GGDGGAAGRGGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGLFGD MMAR_0601|M.marinum_M APAAPVQRAPEVPVLPAPAVPEPVVAVPPLVPIVVPPVRVPSGTDTFLRP MAV_3950|M.avium_104 ----------GYPHYFGGGYHNGIFFQPGFYPYPFWGPGWGWALGDVLLM Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 GGAGGAGAAGGFGGISAATPSAGSEGAMGGAG------------------ MMAR_0601|M.marinum_M SVPKVQAPVPRQQPKAPAPRVEVPASPP---------------------- MAV_3950|M.avium_104 DALLDDHWGGGFERGFEAGRDAAFADAG---------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv FAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 ---------GVGGNARLLGTGGAGGVGGGGGAGGDGGRG--GVATPGGQG MMAR_0601|M.marinum_M ------------PVVSPNPRGRGGLRLPGLGRIPNPGRGPAGGSLGPGRR MAV_3950|M.avium_104 ----------------------SHNAAANYEAANYDGGYDAGGDIGFDGG Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSI MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 GDAGDGGAGGAGGNGGGGASGAG----GWLLGTGGAG------------- MMAR_0601|M.marinum_M GHFGGGAPGRSGPSGGGHG------------------------------- MAV_3950|M.avium_104 WDSGAGWDSGGSDSGGDIGF------------------------------ Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv DGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGAGGLG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -----GAGGNGGNGGKAGFSPG---PTNFGLNGAGGGGGVGGNGATG--- MMAR_0601|M.marinum_M -----GQFGGGGHGGRFG-------------GGGHGGGFGGGRGGGGHGG MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGN MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 -----PWLFGDGGAGGGGGAGGIGGDGGPTPGS--------TGAGAAGGH MMAR_0601|M.marinum_M GFGGFGGGHGGGGHGGGFGGGHGGGFGGGHGGR----------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2584|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4681|M.smegmatis_MC2_155 -------------------------------------------------- TH_0349|M.thermoresistible__bu -------------------------------------------------- MAB_1577c|M.abscessus_ATCC_199 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGGGTDG MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mb1116|M.bovis_AF2122/97 GGDAQLIGNGGHGGAGGTGVPNGSGGAGGLSG----LLFGEPGANG---- MMAR_0601|M.marinum_M -------------------------------------------------- MAV_3950|M.avium_104 -------------------------------------------------- Mvan_4049|M.vanbaalenii_PYR-1 ------------- Mflv_2584|M.gilvum_PYR-GCK ------------- MSMEG_4681|M.smegmatis_MC2_155 ------------- TH_0349|M.thermoresistible__bu ------------- MAB_1577c|M.abscessus_ATCC_199 ------------- Rv3508|M.tuberculosis_H37Rv DDGNGGSPGTDGS MUL_3672|M.ulcerans_Agy99 ------------- Mb1116|M.bovis_AF2122/97 ------------- MMAR_0601|M.marinum_M ------------- MAV_3950|M.avium_104 -------------