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VSLRIGILGASRIAASAIVEPARELGHRLIAVAARDPLRTQAFADKYGVERVLASYQDVVTDPQVDIVYN PLANALHAPWNLAAVAAGKPVLTEKPYARDRGEAARVAAAADAAGVTVMEGFHYLFHPVTQRALSLAGDG TLGELTRIEVRMGMPAPQSDDPRWSLELAGGALMDLGCYGLHVMRRFGTPSVLAATAVQRTPGVDERFDA ELVFPSGLTGLTTNSMVDDEYSFTLRLIGTRGEAFVHDFIKPHDDDRLTLHTEDGTTVERHGTRTSYTYQ LEAFTDHVERGTPIPLDTADAVANMALIDEAYRAAGMSPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3970 | - | - | 100% (320) | oxidoreductase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0541 | - | 2e-10 | 25.27% (186) | oxidoreductase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 2e-09 | 28.43% (204) | inositol 2-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1781 | - | 9e-10 | 42.05% (88) | hypothetical protein Mb1781 |
| M. gilvum PYR-GCK | Mflv_2611 | - | 1e-149 | 79.38% (320) | oxidoreductase domain-containing protein |
| M. tuberculosis H37Rv | Rv1752 | - | 1e-09 | 42.05% (88) | hypothetical protein Rv1752 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2306c | - | 5e-26 | 28.40% (324) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 2e-69 | 45.65% (322) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_2987 | - | 2e-69 | 44.10% (322) | NAD binding oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4652 | - | 1e-122 | 66.06% (327) | D-oliose 4-ketoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3103 | - | 1e-30 | 43.60% (172) | hypothetical protein MUL_3103 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3970|M.vanbaalenii_PYR-1 --------MS-LRIGILGASRIAASAIVEP-ARELGHRLIAVAARDPLRT
Mflv_2611|M.gilvum_PYR-GCK --------MT-LRIGVLGASRIAEAAIVEP-ARELGFRLVAVAARDPQRA
MSMEG_4652|M.smegmatis_MC2_155 --------MTGLRIGILGASRIAEKAIVGP-AEDLGHRLVAVAARDRRRA
MMAR_2628|M.marinum_M ----MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARA
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 MSAMAEVHAPKLRIGILGAARIAPLALIKPSAENPDVVVAAVAARDASRA
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2306c|M.abscessus_ATCC_199 -------MPESIRWGIVGPGRIAG-NVARDFPLTPRAELAAVASRSLPRA
Mvan_3970|M.vanbaalenii_PYR-1 QAFADKYGVERVLASYQDVVTDPQVDIVYNPLANALHAPWNLAAVAAGKP
Mflv_2611|M.gilvum_PYR-GCK NIFADTYGVERVVPTYQDVVTDPEVDVVYNPLANSLHAPWNLAAVAAGKP
MSMEG_4652|M.smegmatis_MC2_155 EAFAEKYGVQRVLDSYRDVVEDPDVDMVYNPLANGLHAPWNLAAIAAGKP
MMAR_2628|M.marinum_M QAFAAKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKH
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 RAFATRHGIATVHDHYEALIADPDIDAIYNPLPNGLHGRWTRAALAAGKH
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2306c|M.abscessus_ATCC_199 QDFAGAHQIPRAYGSYRELLADPDIDAVYIATPHPQHRQTAIAALTAGKA
Mvan_3970|M.vanbaalenii_PYR-1 VLTEKPYARDRGEAARVAAAADAAGVTVMEGFHYLFHPVTQRALSLAGDG
Mflv_2611|M.gilvum_PYR-GCK VLSEKPFARNRAEAARVASAADAAGVTVMEGFHYLFHPVTQRALALAGDG
MSMEG_4652|M.smegmatis_MC2_155 VLSEKPFARNESEAATVAQAARDAGVPVLEGFHYHFHPVTQRAFAVAAGG
MMAR_2628|M.marinum_M VLCEKPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASG
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 VLCEKPFTANAAEAREIADLAEHSDRVVMEAFHYRYHPLTLRAEEIIASG
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2306c|M.abscessus_ATCC_199 ILVEKTFTATVSGAQEVIDIARARGVFAMEAMWTRFQPAIVAAKDLVDDG
Mvan_3970|M.vanbaalenii_PYR-1 TLGELTRIEVRMGMPAPQS-DDPRWSLELAGGALMDLGCYGLHVMRRFG-
Mflv_2611|M.gilvum_PYR-GCK TLGELRRVEVRMGMPEPKP-DDPRWSLELAGGALMDLGCYGVHVLRRFG-
MSMEG_4652|M.smegmatis_MC2_155 ELGEITRVEVRMAMPSPAD-DDPRWSLDLAGGAVMDLGCYGIHVMRALGA
MMAR_2628|M.marinum_M ELGTLQRVETSMCFPLPKF-SDIRYNYALAGGATMDAGCYAVHMARTFG-
MUL_3103|M.ulcerans_Agy99 -----------MRFPLPKF-SDIRYNYALAGGATMDAGCYAVHMARTFG-
MAV_2987|M.avium_104 ELGTLQHVEAALCFPLPKF-SDIRYDYALAGGATMDAGCYAVHMARTFG-
Mb1781|M.bovis_AF2122/97 ----------------------------------MDAGCYAVHMAHTFG-
Rv1752|M.tuberculosis_H37Rv ----------------------------------MDAGCYAVHMAHTFG-
MAB_2306c|M.abscessus_ATCC_199 AIGEVRQVQADLGVDRPFDREDRLFNPALGGGALLDLGVYVVSLAQYFLG
:* * * : : : :
Mvan_3970|M.vanbaalenii_PYR-1 --------TPSVLAATAVQRTPGVDERFDAELVFPSGLTGLTTNSMVDDE
Mflv_2611|M.gilvum_PYR-GCK --------VPSILSATAVQRSAGVDATLDAEVVFPSGLTGLTANSMVQDD
MSMEG_4652|M.smegmatis_MC2_155 MRVDGLGGEPKVLGARAEERTPGVDAWCEVDFVFPEGGTGVSTNSMVADD
MMAR_2628|M.marinum_M ------GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIQCSMWSSH
MUL_3103|M.ulcerans_Agy99 ------GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIEFSMWSSH
MAV_2987|M.avium_104 ------GRSPEVVSAQAKLRGPKVDRAMTAELRFPAGHTGRVRCSMWSTR
Mb1781|M.bovis_AF2122/97 ------GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSD
Rv1752|M.tuberculosis_H37Rv ------GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSD
MAB_2306c|M.abscessus_ATCC_199 --------DPAAVVAHGSLFPTGVDAEAGLLLRYDDGRTATLLCSLLHHT
* : * . . ** . : * :. *:
Mvan_3970|M.vanbaalenii_PYR-1 YS-FTLRLIGTRGEAFVHDFIKPHDDDRLTLHTEDGTTVERHGTRTSYTY
Mflv_2611|M.gilvum_PYR-GCK FS-FTLRLIGSRGEAFVHNFIKPRDDDRLTVQTDDGTRVERFGTRASYTY
MSMEG_4652|M.smegmatis_MC2_155 YS-FTITITGSDGEAVVHDFIRPNLDDRLTVMTGSGVRVEHLGTRPSYTY
MMAR_2628|M.marinum_M LLNMSARVVGDRGELRVLNPVVPQLFHRLTVQSAIGRRVERFPRRASYAY
MUL_3103|M.ulcerans_Agy99 LLNMSARVVGDRGELRVLNPVVPHLFHRLTVQSAIGRRVERFPRRASYVY
MAV_2987|M.avium_104 LLQISARVVGEHGELRIVNPVLPQAFHRLTVRSRDGRRTERFERRASYAY
Mb1781|M.bovis_AF2122/97 LLNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASG
Rv1752|M.tuberculosis_H37Rv LLNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASG
MAB_2306c|M.abscessus_ATCC_199 PG--QARIFGTEGWIDILPRFHHPREIVLHRKGAAPEPMVRPPVGGGYSH
: * * : . * :
Mvan_3970|M.vanbaalenii_PYR-1 QLEAFTDHVERGTPIP--LDTADAVANMALIDEAYRAAGMSPR-------
Mflv_2611|M.gilvum_PYR-GCK QLEFFARHVLHGAPLP--LDTTDAVENMAVIDEIYRAAGLPVR-------
MSMEG_4652|M.smegmatis_MC2_155 QLEAFAAHVRDGAPLP--FGVDDAVTNMAFVDKAYRAAGLAPR-------
MMAR_2628|M.marinum_M QLDAFTGAILRGEAVK--TTPQDAVQNMTVIDAIYRAAGLPLRNPS----
MUL_3103|M.ulcerans_Agy99 QLDAFTGAILRGEAVK--TTPQDAVQNMTVIDAIYRAAGLPLRNPS----
MAV_2987|M.avium_104 QLDAFAAGVLRGEPVK--TSARDAVDNMTVIDAIYRAAGLPLRYPT----
Mb1781|M.bovis_AF2122/97 QDDAQG----RGREHE--RDPRDLSGRRAPIAQPELNMVAASGSAA----
Rv1752|M.tuberculosis_H37Rv QDDAQG----RGREHE--RDPRDLSGRRAPIAQPELNMVAASGSAA----
MAB_2306c|M.abscessus_ATCC_199 ELAEVTECLLNGRAQSSVMPLADTLAVQRVLNTACEQLGVDHTEDPADLD
: * * :