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MRFPLPKFSDIRYNYALAGGATMDAGCYAVHMARTFGGGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHS GRIEFSMWSSHLLNMSARVVGDRGELRVLNPVVPHLFHRLTVQSAIGRRVERFPRRASYVYQLDAFTGAI LRGEAVKTTPQDAVQNMTVIDAIYRAAGLPLRNPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3103 | - | - | 100% (175) | hypothetical protein MUL_3103 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1781 | - | 6e-37 | 76.29% (97) | hypothetical protein Mb1781 |
| M. gilvum PYR-GCK | Mflv_2611 | - | 4e-35 | 47.67% (172) | oxidoreductase domain-containing protein |
| M. tuberculosis H37Rv | Rv1752 | - | 7e-37 | 76.29% (97) | hypothetical protein Rv1752 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2306c | - | 2e-05 | 30.00% (140) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 8e-95 | 97.14% (175) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_2987 | - | 4e-75 | 77.46% (173) | NAD binding oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4652 | - | 8e-26 | 38.55% (179) | D-oliose 4-ketoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3970 | - | 8e-31 | 43.60% (172) | oxidoreductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2611|M.gilvum_PYR-GCK --------MT-LRIGVLGASRIAEAAIVEP-ARELGFRLVAVAARDPQRA
Mvan_3970|M.vanbaalenii_PYR-1 --------MS-LRIGILGASRIAASAIVEP-ARELGHRLIAVAARDPLRT
MSMEG_4652|M.smegmatis_MC2_155 --------MTGLRIGILGASRIAEKAIVGP-AEDLGHRLVAVAARDRRRA
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2628|M.marinum_M ----MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARA
MAV_2987|M.avium_104 MSAMAEVHAPKLRIGILGAARIAPLALIKPSAENPDVVVAAVAARDASRA
MAB_2306c|M.abscessus_ATCC_199 -------MPESIRWGIVGPGRIAG-NVARDFPLTPRAELAAVASRSLPRA
Mflv_2611|M.gilvum_PYR-GCK NIFADTYGVERVVPTYQDVVTDPEVDVVYNPLANSLHAPWNLAAVAAGKP
Mvan_3970|M.vanbaalenii_PYR-1 QAFADKYGVERVLASYQDVVTDPQVDIVYNPLANALHAPWNLAAVAAGKP
MSMEG_4652|M.smegmatis_MC2_155 EAFAEKYGVQRVLDSYRDVVEDPDVDMVYNPLANGLHAPWNLAAIAAGKP
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2628|M.marinum_M QAFAAKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKH
MAV_2987|M.avium_104 RAFATRHGIATVHDHYEALIADPDIDAIYNPLPNGLHGRWTRAALAAGKH
MAB_2306c|M.abscessus_ATCC_199 QDFAGAHQIPRAYGSYRELLADPDIDAVYIATPHPQHRQTAIAALTAGKA
Mflv_2611|M.gilvum_PYR-GCK VLSEKPFARNRAEAARVASAADAAGVTVMEGFHYLFHPVTQRALALAGDG
Mvan_3970|M.vanbaalenii_PYR-1 VLTEKPYARDRGEAARVAAAADAAGVTVMEGFHYLFHPVTQRALSLAGDG
MSMEG_4652|M.smegmatis_MC2_155 VLSEKPFARNESEAATVAQAARDAGVPVLEGFHYHFHPVTQRAFAVAAGG
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2628|M.marinum_M VLCEKPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASG
MAV_2987|M.avium_104 VLCEKPFTANAAEAREIADLAEHSDRVVMEAFHYRYHPLTLRAEEIIASG
MAB_2306c|M.abscessus_ATCC_199 ILVEKTFTATVSGAQEVIDIARARGVFAMEAMWTRFQPAIVAAKDLVDDG
Mflv_2611|M.gilvum_PYR-GCK TLGELRRVEVRMGMPEPKP-DDPRWSLELAGGALMDLGCYGVHVLRRFG-
Mvan_3970|M.vanbaalenii_PYR-1 TLGELTRIEVRMGMPAPQS-DDPRWSLELAGGALMDLGCYGLHVMRRFG-
MSMEG_4652|M.smegmatis_MC2_155 ELGEITRVEVRMAMPSPAD-DDPRWSLDLAGGAVMDLGCYGIHVMRALGA
Mb1781|M.bovis_AF2122/97 ----------------------------------MDAGCYAVHMAHTFG-
Rv1752|M.tuberculosis_H37Rv ----------------------------------MDAGCYAVHMAHTFG-
MUL_3103|M.ulcerans_Agy99 -----------MRFPLPKF-SDIRYNYALAGGATMDAGCYAVHMARTFG-
MMAR_2628|M.marinum_M ELGTLQRVETSMCFPLPKF-SDIRYNYALAGGATMDAGCYAVHMARTFG-
MAV_2987|M.avium_104 ELGTLQHVEAALCFPLPKF-SDIRYDYALAGGATMDAGCYAVHMARTFG-
MAB_2306c|M.abscessus_ATCC_199 AIGEVRQVQADLGVDRPFDREDRLFNPALGGGALLDLGVYVVSLAQYFLG
:* * * : : : :
Mflv_2611|M.gilvum_PYR-GCK --------VPSILSATAVQRSAGVDATLDAEVVFPSGLTGLTANSMVQDD
Mvan_3970|M.vanbaalenii_PYR-1 --------TPSVLAATAVQRTPGVDERFDAELVFPSGLTGLTTNSMVDDE
MSMEG_4652|M.smegmatis_MC2_155 MRVDGLGGEPKVLGARAEERTPGVDAWCEVDFVFPEGGTGVSTNSMVADD
Mb1781|M.bovis_AF2122/97 ------GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSD
Rv1752|M.tuberculosis_H37Rv ------GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSD
MUL_3103|M.ulcerans_Agy99 ------GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIEFSMWSSH
MMAR_2628|M.marinum_M ------GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIQCSMWSSH
MAV_2987|M.avium_104 ------GRSPEVVSAQAKLRGPKVDRAMTAELRFPAGHTGRVRCSMWSTR
MAB_2306c|M.abscessus_ATCC_199 --------DPAAVVAHGSLFPTGVDAEAGLLLRYDDGRTATLLCSLLHHT
* : * . . ** . : * :. *:
Mflv_2611|M.gilvum_PYR-GCK FS-FTLRLIGSRGEAFVHNFIKPRDDDRLTVQTDDGTRVERFGTRASYTY
Mvan_3970|M.vanbaalenii_PYR-1 YS-FTLRLIGTRGEAFVHDFIKPHDDDRLTLHTEDGTTVERHGTRTSYTY
MSMEG_4652|M.smegmatis_MC2_155 YS-FTITITGSDGEAVVHDFIRPNLDDRLTVMTGSGVRVEHLGTRPSYTY
Mb1781|M.bovis_AF2122/97 LLNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASG
Rv1752|M.tuberculosis_H37Rv LLNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASG
MUL_3103|M.ulcerans_Agy99 LLNMSARVVGDRGELRVLNPVVPHLFHRLTVQSAIGRRVERFPRRASYVY
MMAR_2628|M.marinum_M LLNMSARVVGDRGELRVLNPVVPQLFHRLTVQSAIGRRVERFPRRASYAY
MAV_2987|M.avium_104 LLQISARVVGEHGELRIVNPVLPQAFHRLTVRSRDGRRTERFERRASYAY
MAB_2306c|M.abscessus_ATCC_199 PG--QARIFGTEGWIDILPRFHHPREIVLHRKGAAPEPMVRPPVGGGYSH
: * * : . * :
Mflv_2611|M.gilvum_PYR-GCK QLEFFARHVLHGAPLP--LDTTDAVENMAVIDEIYRAAGLPVR-------
Mvan_3970|M.vanbaalenii_PYR-1 QLEAFTDHVERGTPIP--LDTADAVANMALIDEAYRAAGMSPR-------
MSMEG_4652|M.smegmatis_MC2_155 QLEAFAAHVRDGAPLP--FGVDDAVTNMAFVDKAYRAAGLAPR-------
Mb1781|M.bovis_AF2122/97 QDDAQG----RGREHE--RDPRDLSGRRAPIAQPELNMVAASGSAA----
Rv1752|M.tuberculosis_H37Rv QDDAQG----RGREHE--RDPRDLSGRRAPIAQPELNMVAASGSAA----
MUL_3103|M.ulcerans_Agy99 QLDAFTGAILRGEAVK--TTPQDAVQNMTVIDAIYRAAGLPLRNPS----
MMAR_2628|M.marinum_M QLDAFTGAILRGEAVK--TTPQDAVQNMTVIDAIYRAAGLPLRNPS----
MAV_2987|M.avium_104 QLDAFAAGVLRGEPVK--TSARDAVDNMTVIDAIYRAAGLPLRYPT----
MAB_2306c|M.abscessus_ATCC_199 ELAEVTECLLNGRAQSSVMPLADTLAVQRVLNTACEQLGVDHTEDPADLD
: * * :