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MDAGCYAVHMAHTFGGATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSDLLNVSARVVGD RGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASGQDDAQGRGREHERDPRDLSGRRAPIAQPELN MVAASGSAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1752 | - | - | 100% (149) | hypothetical protein Rv1752 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1781 | - | 2e-83 | 100.00% (149) | hypothetical protein Mb1781 |
| M. gilvum PYR-GCK | Mflv_2611 | - | 2e-10 | 40.91% (88) | oxidoreductase domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2628 | - | 4e-39 | 71.68% (113) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_2987 | - | 1e-36 | 64.10% (117) | NAD binding oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4652 | - | 2e-07 | 33.68% (95) | D-oliose 4-ketoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3103 | - | 5e-37 | 76.29% (97) | hypothetical protein MUL_3103 |
| M. vanbaalenii PYR-1 | Mvan_3970 | - | 4e-10 | 42.05% (88) | oxidoreductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2628|M.marinum_M ----MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARA
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 MSAMAEVHAPKLRIGILGAARIAPLALIKPSAENPDVVVAAVAARDASRA
Mflv_2611|M.gilvum_PYR-GCK --------MT-LRIGVLGASRIAEAAIVEP-ARELGFRLVAVAARDPQRA
Mvan_3970|M.vanbaalenii_PYR-1 --------MS-LRIGILGASRIAASAIVEP-ARELGHRLIAVAARDPLRT
MSMEG_4652|M.smegmatis_MC2_155 --------MTGLRIGILGASRIAEKAIVGP-AEDLGHRLVAVAARDRRRA
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2628|M.marinum_M QAFAAKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKH
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 RAFATRHGIATVHDHYEALIADPDIDAIYNPLPNGLHGRWTRAALAAGKH
Mflv_2611|M.gilvum_PYR-GCK NIFADTYGVERVVPTYQDVVTDPEVDVVYNPLANSLHAPWNLAAVAAGKP
Mvan_3970|M.vanbaalenii_PYR-1 QAFADKYGVERVLASYQDVVTDPQVDIVYNPLANALHAPWNLAAVAAGKP
MSMEG_4652|M.smegmatis_MC2_155 EAFAEKYGVQRVLDSYRDVVEDPDVDMVYNPLANGLHAPWNLAAIAAGKP
Rv1752|M.tuberculosis_H37Rv --------------------------------------------------
Mb1781|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2628|M.marinum_M VLCEKPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASG
MUL_3103|M.ulcerans_Agy99 --------------------------------------------------
MAV_2987|M.avium_104 VLCEKPFTANAAEAREIADLAEHSDRVVMEAFHYRYHPLTLRAEEIIASG
Mflv_2611|M.gilvum_PYR-GCK VLSEKPFARNRAEAARVASAADAAGVTVMEGFHYLFHPVTQRALALAGDG
Mvan_3970|M.vanbaalenii_PYR-1 VLTEKPYARDRGEAARVAAAADAAGVTVMEGFHYLFHPVTQRALSLAGDG
MSMEG_4652|M.smegmatis_MC2_155 VLSEKPFARNESEAATVAQAARDAGVPVLEGFHYHFHPVTQRAFAVAAGG
Rv1752|M.tuberculosis_H37Rv ---------------------------------MDAGCYAVHMAHTFG--
Mb1781|M.bovis_AF2122/97 ---------------------------------MDAGCYAVHMAHTFG--
MMAR_2628|M.marinum_M ELGTLQRVETSMCFPLPKFSDIRYNYALAGGATMDAGCYAVHMARTFG--
MUL_3103|M.ulcerans_Agy99 -----------MRFPLPKFSDIRYNYALAGGATMDAGCYAVHMARTFG--
MAV_2987|M.avium_104 ELGTLQHVEAALCFPLPKFSDIRYDYALAGGATMDAGCYAVHMARTFG--
Mflv_2611|M.gilvum_PYR-GCK TLGELRRVEVRMGMPEPKPDDPRWSLELAGGALMDLGCYGVHVLRRFG--
Mvan_3970|M.vanbaalenii_PYR-1 TLGELTRIEVRMGMPAPQSDDPRWSLELAGGALMDLGCYGLHVMRRFG--
MSMEG_4652|M.smegmatis_MC2_155 ELGEITRVEVRMAMPSPADDDPRWSLDLAGGAVMDLGCYGIHVMRALGAM
** ***.:*: : :*
Rv1752|M.tuberculosis_H37Rv -----GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSDL
Mb1781|M.bovis_AF2122/97 -----GATPEVVSAQAKLRDPAVDRAMTAELKFPGGHTGGIRCSMRSSDL
MMAR_2628|M.marinum_M -----GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIQCSMWSSHL
MUL_3103|M.ulcerans_Agy99 -----GGTPEVVSAQAKRRDSEVDRAMTAELRFPAGHSGRIEFSMWSSHL
MAV_2987|M.avium_104 -----GRSPEVVSAQAKLRGPKVDRAMTAELRFPAGHTGRVRCSMWSTRL
Mflv_2611|M.gilvum_PYR-GCK -------VPSILSATAVQRSAGVDATLDAEVVFPSGLTGLTANSMVQDDF
Mvan_3970|M.vanbaalenii_PYR-1 -------TPSVLAATAVQRTPGVDERFDAELVFPSGLTGLTTNSMVDDEY
MSMEG_4652|M.smegmatis_MC2_155 RVDGLGGEPKVLGARAEERTPGVDAWCEVDFVFPEGGTGVSTNSMVADDY
*.::.* * * . ** .:. ** * :* **
Rv1752|M.tuberculosis_H37Rv LNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASGQ
Mb1781|M.bovis_AF2122/97 LNVSARVVGDRGELRVLNPVVPQLFHRLPPLACVSARRFRCRSAARASGQ
MMAR_2628|M.marinum_M LNMSARVVGDRGELRVLNPVVPQLFHRLTVQSAIGRRVERFPRRASYAYQ
MUL_3103|M.ulcerans_Agy99 LNMSARVVGDRGELRVLNPVVPHLFHRLTVQSAIGRRVERFPRRASYVYQ
MAV_2987|M.avium_104 LQISARVVGEHGELRIVNPVLPQAFHRLTVRSRDGRRTERFERRASYAYQ
Mflv_2611|M.gilvum_PYR-GCK S-FTLRLIGSRGEAFVHNFIKPRDDDRLTVQTDDGTRVERFGTRASYTYQ
Mvan_3970|M.vanbaalenii_PYR-1 S-FTLRLIGTRGEAFVHDFIKPHDDDRLTLHTEDGTTVERHGTRTSYTYQ
MSMEG_4652|M.smegmatis_MC2_155 S-FTITITGSDGEAVVHDFIRPNLDDRLTVMTGSGVRVEHLGTRPSYTYQ
.: : * ** : : : *. .**. : . : . *
Rv1752|M.tuberculosis_H37Rv DDAQG----RGREHERDPRDLSGRRAPIAQPELNMVAASGSAA
Mb1781|M.bovis_AF2122/97 DDAQG----RGREHERDPRDLSGRRAPIAQPELNMVAASGSAA
MMAR_2628|M.marinum_M LDAFTGAILRGEAVKTTPQDAVQNMTVIDAIYRAAGLPLRNPS
MUL_3103|M.ulcerans_Agy99 LDAFTGAILRGEAVKTTPQDAVQNMTVIDAIYRAAGLPLRNPS
MAV_2987|M.avium_104 LDAFAAGVLRGEPVKTSARDAVDNMTVIDAIYRAAGLPLRYPT
Mflv_2611|M.gilvum_PYR-GCK LEFFARHVLHGAPLPLDTTDAVENMAVIDEIYRAAGLPVR---
Mvan_3970|M.vanbaalenii_PYR-1 LEAFTDHVERGTPIPLDTADAVANMALIDEAYRAAGMSPR---
MSMEG_4652|M.smegmatis_MC2_155 LEAFAAHVRDGAPLPFGVDDAVTNMAFVDKAYRAAGLAPR---
: * * . : : .