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ADLDELYGEIPTRQIAARLGADEAEVSSAVKTLLPVLVGGLQQNALDPGTASTIASAANSHAGLLDGGVD VDQVDEVDGSKAVAKIFGGNDTGQVASALSGGGAGNSDLINRLLPILAPIVLAYIGRKLSGGQAQPQGQS GGGLGDILGGILGGGGQRGAGADNPLGSILGSVLGGDKGGPLGDILGGLLGGKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3952 | - | - | 100% (195) | hypothetical protein Mvan_3952 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0285c | PE_PGRS3a | 1e-07 | 33.73% (169) | hypothetical protein Mb0285c |
| M. gilvum PYR-GCK | Mflv_2629 | - | 2e-78 | 77.44% (195) | hypothetical protein Mflv_2629 |
| M. tuberculosis H37Rv | Rv1067c | PE_PGRS19 | 2e-07 | 31.91% (141) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1602 | - | 2e-55 | 58.05% (205) | hypothetical protein MAB_1602 |
| M. marinum M | MMAR_3774 | - | 8e-57 | 60.78% (204) | hypothetical protein MMAR_3774 |
| M. avium 104 | MAV_2780 | - | 1e-06 | 33.04% (112) | hypothetical protein MAV_2780 |
| M. smegmatis MC2 155 | MSMEG_4631 | - | 2e-59 | 61.76% (204) | hypothetical protein MSMEG_4631 |
| M. thermoresistible (build 8) | TH_3772 | - | 2e-06 | 52.83% (53) | PUTATIVE putative AAA ATPase containing von Willebrand factor |
| M. ulcerans Agy99 | MUL_3721 | - | 1e-54 | 59.61% (203) | hypothetical protein MUL_3721 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 ----------MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALL
Rv1067c|M.tuberculosis_H37Rv ----------MSFVLVSPSQLMAAAADVAGIGSAISAANAAALAPTSVLA
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu MAKHTKTTRRSKKLATLGVATATATATALTVGAAPPEVETSALRNADVDL
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 AAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFTQALTSGGGAYAAA
Rv1067c|M.tuberculosis_H37Rv AAGADEVSAAVAALFSAHAGQYQQLGARAALFHEQFVQALTGAASAYASA
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu LAGIQFYPEPEHIPDLTFGLGAVGYGLSQDFAEMAIRGLVDNISFAALAE
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 EAA-ATSPLLAPINEFFLANTGRPLIGNGANGAPGTGADGAPGGWLIGNG
Rv1067c|M.tuberculosis_H37Rv EATNVEQQVLGLINAPTQALLGRPLIGNGADGTAAN-PNGGAGGLLYGN-
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu ALGLDLQSQLENVLNNALAMLLGPVFGTLGQIPLDLDLVGLVGGLLDQKI
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 GAGGSGAANNAVGGTGGTGGAGGASGLLGSGGAGGAGG----------VA
Rv1067c|M.tuberculosis_H37Rv --GGNGFSQTTAGLTGGTG---GSAGLIGNGGNGGAGG----------AG
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu TAELADTLRPVLEGLEDLPFLGSILGDILGPILGGNGNNGLVDMVLGELL
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 TNTGGIGGAGGTGGNAVLFGAGGAGGASTNTTGGAGGAGGDGGNAGLLFG
Rv1067c|M.tuberculosis_H37Rv AN----GGAGGNGG--WLYGSGGNG--------GAGGAGPAG--------
MAV_2780|M.avium_104 -----------------MFG------------------------------
TH_3772|M.thermoresistible__bu GDIIGGILPGAELDLDSLGGLLGLLGLDLSQPLNLSNLNLGLNLVTTGPL
Mvan_3952|M.vanbaalenii_PYR-1 ----------------------MADLDELYGEIPTRQIAARLGADEAEVS
Mflv_2629|M.gilvum_PYR-GCK ----------------------MTDLDDLYSEIPTQQIAQRLGADEREVG
MMAR_3774|M.marinum_M ----------------------MAGLDDLYARIPTSEIASRLGVDQGEVD
MUL_3721|M.ulcerans_Agy99 -------------------MASMAGLDDLYARIPTSEIASRLGVDQGEVD
MAB_1602|M.abscessus_ATCC_1997 ----------------------MATLDELLNEIPTDQIAAKLGVDNETAD
MSMEG_4631|M.smegmatis_MC2_155 ----------------------MAGLDELFAQIPVADIANKVGADEGEVT
Mb0285c|M.bovis_AF2122/97 AAGVGGAGGFALATTASGGAGGAGGAGGMFTDGGVGGVGGKGGFGGAG-G
Rv1067c|M.tuberculosis_H37Rv --AIGAPG-------VAGGAGGAGGTAGLFGNGGVGGVGGDGGQGGNGAG
MAV_2780|M.avium_104 ------------------------GAAMLVLAVGCG--GGHKG------G
TH_3772|M.thermoresistible__bu FTALKLFGADLGWEPALPNAVAREINETEYLNVGLLSLLNTLGLEDLSAA
*
Mvan_3952|M.vanbaalenii_PYR-1 SAVKTLLPVLVGGLQQN-----------------------ALDPGTASTI
Mflv_2629|M.gilvum_PYR-GCK DAVKTLLPVLVGGLQHN-----------------------AADPGTASAI
MMAR_3774|M.marinum_M SAVHTLVPVLVSGLHQT-----------------------SQDPDHASRI
MUL_3721|M.ulcerans_Agy99 SAVHVPVPVLVSGLHQT-----------------------SQDPDHASRI
MAB_1602|M.abscessus_ATCC_1997 KAIKSVVPLLVGGLQAN-----------------------ADDPDKAADL
MSMEG_4631|M.smegmatis_MC2_155 AAIKTLVPALVGGLQQNV---------------------AADDIDSAPLE
Mb0285c|M.bovis_AF2122/97 AGGNGGLFGAGGTGGAGGTIGAGVAGMGGAGGAGGAGGLFGAGGTGGSGG
Rv1067c|M.tuberculosis_H37Rv AGASGTKGGDAGAGGAGG-AGGWIHGHGGAGGDGGAG---GAGGQASPGA
MAV_2780|M.avium_104 PSTTST-----------------------------------TTPTTTPST
TH_3772|M.thermoresistible__bu LGDLPIVGDLPDLIALRVPIVIGVG--------------LGAFAAGAAYN
. .
Mvan_3952|M.vanbaalenii_PYR-1 ASAANSHAG--LLDGG-----------------VDVDQVDEVDGSKAVAK
Mflv_2629|M.gilvum_PYR-GCK ASAANNHAG--LLDGG-----------------VDVEQVDEADGSKAVAK
MMAR_3774|M.marinum_M ESAANRQAARGLLDAGGGLD-------------HNLDAADRGDGHQTIAT
MUL_3721|M.ulcerans_Agy99 ESAANRQAARGLLDAGGGLD-------------HNLDAADRGDGHQTIAT
MAB_1602|M.abscessus_ATCC_1997 QANVNSAPS-TLLDGG-----------------VNVDDVDQQAGNAVVAS
MSMEG_4631|M.smegmatis_MC2_155 SAVTEQAAS-GLLDGG-----------------VNVDDVDEKQGDNLVAH
Mb0285c|M.bovis_AF2122/97 GGATTGGDGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITG
Rv1067c|M.tuberculosis_H37Rv PGPPSQ-PGGAGGAGGAG----GRGGDGGSAGWLSGNGGDAGNGG----G
MAV_2780|M.avium_104 SVVPSTTPGGGG----------------------TVPGGPTGGGG-----
TH_3772|M.thermoresistible__bu QVVADLANQPGGVNGAESLLGSYTILPMILLRNPGRANGGLFARMYPLAG
Mvan_3952|M.vanbaalenii_PYR-1 IFGGNDTGQVASALSGGG----------AGNSDLIN--------------
Mflv_2629|M.gilvum_PYR-GCK IFGGNDTGQVAAALSGGG----------AGNSDLIN--------------
MMAR_3774|M.marinum_M LFGGNDAEQVASALAKGG----------AGNRDLLR--------------
MUL_3721|M.ulcerans_Agy99 LFGGNDAEQVASALAKGG----------AGNRDLLK--------------
MAB_1602|M.abscessus_ATCC_1997 LFGDNNADDVAAKLAGAG----------AGNSDLIK--------------
MSMEG_4631|M.smegmatis_MC2_155 LFGGNDSNAVASALAGTG----------AGNGDLIK--------------
Mb0285c|M.bovis_AF2122/97 PGGTGGAGGIPGLIGNGG----------NGGDGGASVTGTGGNGGAGGNG
Rv1067c|M.tuberculosis_H37Rv GGTAGGAGNGGQFGGDGG----------TGGTGGT--AGAGGNGGRG--A
MAV_2780|M.avium_104 PGGGGGS-IPGGPTGGGG----------PGGGGGS---------------
TH_3772|M.thermoresistible__bu LFGIDTVTPETSAQSSGGTVPVLGTGLTVGGANLIPVKIDATAEYDFLSD
. . * *. .
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 VQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVSTSVHTLQQA
Rv1067c|M.tuberculosis_H37Rv VLFGHGGNAGHGGAGGNGAAAGAG--------------------------
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu FAAWPNPFSMANNVAALLFPTYLLRGLSALDLVDSLG-------------
Mvan_3952|M.vanbaalenii_PYR-1 ------------RLLPILAPIVLAYIGRKLSGG---QAQPQG--------
Mflv_2629|M.gilvum_PYR-GCK ------------KLLPILAPIVLAYLGRKLSGG---QSTP----------
MMAR_3774|M.marinum_M ------------QLLPIVLPIVLAYIGNQLGSGEGSQQNSES--------
MUL_3721|M.ulcerans_Agy99 ------------QLLPIVLPIVLAYIGNQLGSGEGSQQNSES--------
MAB_1602|M.abscessus_ATCC_1997 ------------QLLPILTPIVLAFVAKKLTGGGAAAAPAEAP-------
MSMEG_4631|M.smegmatis_MC2_155 ------------KLLPILAPIVLAYIGKQFS---QQNAPAQQ--------
Mb0285c|M.bovis_AF2122/97 ALNVVNEPFQTLTGRPLIGNGANGTPGTGAAGGAGGWLFGNGGNGGHGA-
Rv1067c|M.tuberculosis_H37Rv ------------------GEHVVATAGKGGTGGVG----GDGGGG-----
MAV_2780|M.avium_104 ------------------------IPG-GPTGGGG---------------
TH_3772|M.thermoresistible__bu -----------EQLTPQLAQILDNVLQLDEALAINLYLTLPMNTLPLLEP
Mvan_3952|M.vanbaalenii_PYR-1 -------------------QSGGGLGDILGGILG-----------GGGQR
Mflv_2629|M.gilvum_PYR-GCK ---------------------------------------------GGG--
MMAR_3774|M.marinum_M -------------------SSRGGLGEVLGSILG-----------GGS--
MUL_3721|M.ulcerans_Agy99 -------------------ASRGGLGEVLGCILG-----------GGS--
MAB_1602|M.abscessus_ATCC_1997 ------------------AASGGGIGDILGNILGS-------AVGGGAAA
MSMEG_4631|M.smegmatis_MC2_155 ------------------QASGGGLADILGSILGG-------MASGGQQA
Mb0285c|M.bovis_AF2122/97 -----------TNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGG
Rv1067c|M.tuberculosis_H37Rv --------------------GAGGGGGLLYGNGG----------AGGAGN
MAV_2780|M.avium_104 ---------------------PGGGGGSIPGVGG----------------
TH_3772|M.thermoresistible__bu LYLATDFINLFTPGFDVNNPIATALNPVLTSLVNLG-YTDVYWDDAKGQY
Mvan_3952|M.vanbaalenii_PYR-1 GA-GADNPLGSILGSVLGGDKGG-PLGDILGGLLGGKK------------
Mflv_2629|M.gilvum_PYR-GCK -----DNPLGSILGSVLGGDKGG-PLGNILGGLLGGRK------------
MMAR_3774|M.marinum_M ----GDKTLGSILGSVLGG-KGG-ALGDILGGLLGGKK------------
MUL_3721|M.ulcerans_Agy99 ----VDKSLGSILGSVLGG-KGG-ALGDILGGLLGGKT------------
MAB_1602|M.abscessus_ATCC_1997 GG---NNPLGSILGSVLGSKGGSDALGSILGGLLGGKK------------
MSMEG_4631|M.smegmatis_MC2_155 NQSANNNPLGSILGSVLGG-GQGNAIGEILGGLLGGKK------------
Mb0285c|M.bovis_AF2122/97 AGGAGGVSLLIGSGGTGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGG
Rv1067c|M.tuberculosis_H37Rv SGGDGGTGLNAALGGNGGGGG----VGGNAGAGGTGGSAGWLSGNGGAGG
MAV_2780|M.avium_104 -GG----------GGPGGGGG---CVGNVCGAYP----------------
TH_3772|M.thermoresistible__bu DRTLLEADIPTGFGTLPADVNWLEVPGNLFASLMRGVQDAFEEGLIGPEG
* .. . ..
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 HGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFNAAGGNGGNGGLFGTGGT
Rv1067c|M.tuberculosis_H37Rv SGGS----AGAGGAGGKGGDTPNGLAINPG----IGGNGGDTGNAGNGGN
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu SNVLRTLLGLIG--LDLGGLGAGAAGLSMDGLPELLRDAVEDAVGGLGEL
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 GGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGITTGGGGHGGNAGLLS
Rv1067c|M.tuberculosis_H37Rv GGS-----------AARLFGGGGAG---GAGGTGSTAGSGGSGGTNPPTG
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu GGVSPLSSSQPEAAAVPDLGADTLTLKTGQRAAALNESDGAGLKENSEQP
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 LGASGGAGGSGGASSLAGGAGGTGGNGALLFGFGGAGGAGGHGGAALTSI
Rv1067c|M.tuberculosis_H37Rv LQAAGGNGGSG----HAGGHGGNGG-GAGLLGGGGTGGNGGGGG------
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu QDAAGEKTVIDTSTGDESPQPTPDAPREDAIKPPSSKLRTGSNGRGEVRT
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 QQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFG
Rv1067c|M.tuberculosis_H37Rv -QGGLG------------AAAGGVDGNG------GNGGNGGKGGDAQLVG
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu GLGAPGKHLQQSTERLGQRLQDRADKINDGLRNAGAGLRNGLTAGPSSKS
Mvan_3952|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2629|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3774|M.marinum_M --------------------------------------------------
MUL_3721|M.ulcerans_Agy99 --------------------------------------------------
MAB_1602|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4631|M.smegmatis_MC2_155 --------------------------------------------------
Mb0285c|M.bovis_AF2122/97 NGGDGGAGGFGAGTGGSGGVGGNAVLIGNGGNGGNAGKAGATPGAGGTGG
Rv1067c|M.tuberculosis_H37Rv DGGNGGNG----GKGGAGLIAG---LDGAGG-------------AGGTRG
MAV_2780|M.avium_104 --------------------------------------------------
TH_3772|M.thermoresistible__bu QPKSQPKTAAKVGAGVGATSDSESGGDE----------------------
Mvan_3952|M.vanbaalenii_PYR-1 ------------
Mflv_2629|M.gilvum_PYR-GCK ------------
MMAR_3774|M.marinum_M ------------
MUL_3721|M.ulcerans_Agy99 ------------
MAB_1602|M.abscessus_ATCC_1997 ------------
MSMEG_4631|M.smegmatis_MC2_155 ------------
Mb0285c|M.bovis_AF2122/97 LLLGENGLNGLP
Rv1067c|M.tuberculosis_H37Rv LIFGNAGTPGQ-
MAV_2780|M.avium_104 ------------
TH_3772|M.thermoresistible__bu ------------