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MLVESEDSEQIIARVAALDIGKAELVCCVRVPGRGTRRLQEVSTHSTMARSLTELANHLVESGVQRVVME ATSDYWKPVFYLLEAHGLDPWLVNARDVKHLPGRPKTDVLDAVWLAKLAERQMLRPSFVPPPPIRQLRDL TRYRIDLVATRTAERNRVEKLLEDACIKLSVVASDIFGVSGRAMMAALIAGERDPKVLAQLARSRMRTKI GRLEEAFNGHFNAHHGFLLTRMLARLDGIDADIAVLDEQIEVYLAPFAAAAARLDEIPGIGAVAAAIILA EIGTDMSVFPTAGHLCSWAKFSPGIQSSAGKTKGTASTGHGNRYLAQILGEAAIAASRTDTFLGQRYRRI ARRRGNKRALVAVGRSILVIIWHLLTDPDATFIDLGPDHYTKHLNPETKRRNHIRQLEALGYTVTLTPAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3921 | - | - | 100% (420) | transposase IS116/IS110/IS902 family protein |
| M. vanbaalenii PYR-1 | Mvan_4882 | - | 0.0 | 100.00% (420) | transposase IS116/IS110/IS902 family protein |
| M. vanbaalenii PYR-1 | Mvan_4655 | - | 0.0 | 100.00% (420) | transposase IS116/IS110/IS902 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2447c | - | 3e-45 | 43.97% (232) | transposase |
| M. gilvum PYR-GCK | Mflv_4200 | - | 7e-11 | 24.94% (397) | transposase IS116/IS110/IS902 family protein |
| M. tuberculosis H37Rv | Rv2424c | - | 7e-67 | 44.64% (336) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3782 | - | 2e-13 | 25.96% (389) | transposase |
| M. avium 104 | MAV_0496 | - | 8e-09 | 26.72% (247) | transposase IS116/IS110/IS902 |
| M. smegmatis MC2 155 | MSMEG_4550 | - | 3e-10 | 24.87% (398) | transposase |
| M. thermoresistible (build 8) | TH_3017 | - | 2e-11 | 26.44% (295) | PUTATIVE transposase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3782|M.marinum_M ----------MPTVWAGVDTGKRTHHCVVLDRNGGVLLSRPVDNDETALL
TH_3017|M.thermoresistible__bu ---------------------------VVIDAQGKRLLSQRVANDEATLL
Mflv_4200|M.gilvum_PYR-GCK --------MTTGQVWAGVDVGKEHHWVCAVDDSGKVVLSRRLVNDEQPIR
MSMEG_4550|M.smegmatis_MC2_155 --------MAAGQVWAGVDVGKEHHWVCVVDDSGKVVLSRRLVNDEQPIR
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3921|M.vanbaalenii_PYR-1 MLVESEDSEQIIARVAALDIGKAELVCCVRVPGRGTRRLQEVSTHSTMAR
MAV_0496|M.avium_104 -----------------------------------MVARGRVSNDAAGFA
MMAR_3782|M.marinum_M ELIEAVVGVAAGREVCWATDLNAGGAAMLITLLAAHDQQLLYIPGRIVHH
TH_3017|M.thermoresistible__bu KLISTVATMADGGEVTWAIDLNAGGAALLITLLIAADQRLLYIPGRTVHH
Mflv_4200|M.gilvum_PYR-GCK ELVAEIDELAER--VSWTVDLTTVYAALVLTVLADAGKTVRYLAGRAVWQ
MSMEG_4550|M.smegmatis_MC2_155 ELVAEIDELAER--VLWAVDLTTVYAALLLTVLADAGKTVRYLAGRAVWQ
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv ------------------------------------------MQCRAREE
Mvan_3921|M.vanbaalenii_PYR-1 SLTELANHLVESGVQRVVMEATSDYWKPVFYLLEAHGLDPWLVNARDVKH
MAV_0496|M.avium_104 ALLTLLAEAGDSAAHPIPVGIETDRG-LWVAALRETGRVIYPINPLAASR
MMAR_3782|M.marinum_M AAATYRG-DGKTDAKNARIIADQARMR-TDLQPVRRADPIATDLRLLTSR
TH_3017|M.thermoresistible__bu ASGSYRG-EGKTDAKDAAVIADQARMR-RDLQPLRPGDDITVELRILTSR
Mflv_4200|M.gilvum_PYR-GCK ASATYRGGEAKTDAKDARVIADQARMRGQDLPVLHPDDDLISELRMLTGH
MSMEG_4550|M.smegmatis_MC2_155 ASATYRGGEAKTDAKDARVIADQSRMRGQDLPVLHPNDDLISELRMLTGH
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv R-----PGR-KTDLLDAEWLVHLLECG--LLRGWLIPPADIKAARDVIRY
Mvan_3921|M.vanbaalenii_PYR-1 L-----PGRPKTDVLDAVWLAKLAERQ--MLRPSFVPPPPIRQLRDLTRY
MAV_0496|M.avium_104 YRARHAVSGAKSDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARA
MMAR_3782|M.marinum_M RTDVVCDRVRAINRLRQTLLEYFPPLERAFD-----YSKSKAALTLLSRY
TH_3017|M.thermoresistible__bu RTDLVADRTRTINRLRAQLLEYFPALERAFD-----YSTSKAALLLLTGY
Mflv_4200|M.gilvum_PYR-GCK RADLVADRTRTINRLRQQLVAVCPALERAAQ-----PSQDRGWVILLARY
MSMEG_4550|M.smegmatis_MC2_155 RADLVADRTRTINRLRQQLVAVCPALERAAQ-----LSQDRGWVVLLARY
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv RRKLVEHRTSKLQRLGNVLQDAGIKADSVAS-----SVTPKSVRAMVEAL
Mvan_3921|M.vanbaalenii_PYR-1 RIDLVATRTAERNRVEKLLEDACIKLSVVAS-----DIFGVSGRAMMAAL
MAV_0496|M.avium_104 QQDAVWARQQIGNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTILAAA
MMAR_3782|M.marinum_M QTPDSLRRIGPTRLATWLKARGCRNSATVAQTAVQAAQTQHTTLPTQTVG
TH_3017|M.thermoresistible__bu QTPDGLRRAGAARLAVWLGKRKARNADAVAAKALQAAHAQHTVIPGQQLA
Mflv_4200|M.gilvum_PYR-GCK QRPKAIRQSGVSRLTKVLTDAGVRNAASIAAAAVAAVKTQTMRLPGEEVA
MSMEG_4550|M.smegmatis_MC2_155 QRPKAIRQSGVSRLTKVLTDAGVRNAASIAGAAVAAVKTQTVRLPGEEVA
Mb2447c|M.bovis_AF2122/97 -------------MLADLARGSMRSKIPDLQRALEGRFDDHHAL------
Rv2424c|M.tuberculosis_H37Rv -----IDGERRPAVLADLARGSMRSKIPDLQRALEGRFDDHHAL------
Mvan_3921|M.vanbaalenii_PYR-1 -----IAGERDPKVLAQLARSRMRTKIGRLEEAFNGHFNAHHGF------
MAV_0496|M.avium_104 PTPTQAATLTPARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQPPAVE
: * * . .
MMAR_3782|M.marinum_M AQLVPRLAAEITTIDAELAHVDNEITARFA---DHDSAEILTSMPGFGPV
TH_3017|M.thermoresistible__bu AAMVARLAKEVMALDTEIGDTDAMIEERFH---RHRHAEIIVSMSGFGVT
Mflv_4200|M.gilvum_PYR-GCK AGLIADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGIGFR
MSMEG_4550|M.smegmatis_MC2_155 AGLVADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGMGFR
Mb2447c|M.bovis_AF2122/97 --MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGIGVG
Rv2424c|M.tuberculosis_H37Rv --MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGIGVG
Mvan_3921|M.vanbaalenii_PYR-1 --LLTRMLARLDGIDADIAVLDEQIEVYLAP--FAAAAARLDEIPGIGAV
MAV_0496|M.avium_104 NAMGIQLAALLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGML
: : :: * : : .:.*:*
MMAR_3782|M.marinum_M LAATFLAQIGGNLDGFD-TVDRLACVAGLAPVPRDSGRISGNLHRPRRFN
TH_3017|M.thermoresistible__bu LGAEFLAATGGDMSAFD-SVDRLAGVAGLAPVPRDSGRISGNLQRPRRYN
Mflv_4200|M.gilvum_PYR-GCK LGAEFLAAVG-DPALIG-SADQLAAWAGLAPVSRDSGKRTGRLHTPKRYS
MSMEG_4550|M.smegmatis_MC2_155 LGAELLAAVG-DPALIG-SADQLAAWAGLAPVSRDSRKRTGRLHTPKRYS
Mb2447c|M.bovis_AF2122/97 ASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-TGN
Rv2424c|M.tuberculosis_H37Rv ASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-TGN
Mvan_3921|M.vanbaalenii_PYR-1 AAAIILAEIGTD-MSVFPTAGHLCSWAKFSPGIQSSAGKTKGTASTGHGN
MAV_0496|M.avium_104 AGARVLAEIGDDRTRFA-DARGLKAFAGSAPITRASGKKTVVLHRH-IKN
.* .:: * : . * . .* : * .
MMAR_3782|M.marinum_M RRLLRPCYLAALSSLKNSPASRTFYDRKRAEGK------SHKQALIALAR
TH_3017|M.thermoresistible__bu RRLLRVCYLSALSSIRSDPASRTYYNRKRAEGK------RHSQAVLALAR
Mflv_4200|M.gilvum_PYR-GCK RRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATICLAR
MSMEG_4550|M.smegmatis_MC2_155 RRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATICLAR
Mb2447c|M.bovis_AF2122/97 QHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIAVAH
Rv2424c|M.tuberculosis_H37Rv QHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAITTVAH
Mvan_3921|M.vanbaalenii_PYR-1 RYLAQILGEAAIAASRTDTFLGQRYRRIARRRG-------NKRALVAVGR
MAV_0496|M.avium_104 RRLAAVGPIWALGSLRASPGARRHYDARRAAGD------WNHQAQRHLFN
: * * : : . * * : .
MMAR_3782|M.marinum_M RRINVIWAMLRD-------------HTHYHEPDLVNTPLAA---------
TH_3017|M.thermoresistible__bu RRLNVLWAMLRD-------------HTTYQPTTPTAAAAA----------
Mflv_4200|M.gilvum_PYR-GCK RRTNVLYALIRD-------------NRTWQPDSPPVTAAA----------
MSMEG_4550|M.smegmatis_MC2_155 RRTNVLYALIRD-------------NRTWQPESPPNIAAA----------
Mb2447c|M.bovis_AF2122/97 KLIVIIWHVLAT-GRPYQDLGADYFTTRMDPDKERRRLVAKLEAQGLGVT
Rv2424c|M.tuberculosis_H37Rv KLIVIIWHVLAT-GRPHQDLGADYFTTRMDPDKERRRLVAKLEAQGLGVT
Mvan_3921|M.vanbaalenii_PYR-1 SILVIIWHLLTDPDATFIDLGPDHYTKHLNPETKRRNHIRQLEALGYTVT
MAV_0496|M.avium_104 KFLGQLHHCLQTGRLYNEHLAFPLNRPGFDGGSCYWISTSGWSVRFVA--
: : .
MMAR_3782|M.marinum_M -----
TH_3017|M.thermoresistible__bu -----
Mflv_4200|M.gilvum_PYR-GCK -----
MSMEG_4550|M.smegmatis_MC2_155 -----
Mb2447c|M.bovis_AF2122/97 LEPAA
Rv2424c|M.tuberculosis_H37Rv LEPAA
Mvan_3921|M.vanbaalenii_PYR-1 LTPAA
MAV_0496|M.avium_104 -----