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MLVGMSIAGPIVTLGAVAALATGILLADLTLNPNPQPPAPPSPAAVAAPAPAAPVPPPPVPPPPVPFGPQ QDFVADISTKTGTLPLQIRVVGDTADAYACDNAGIETWLSGSAVGGVLKLTSTDRTARLDGRHRDGTVVG TLWIGDRHWDFTAVPGATDAF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3862 | - | - | 100% (161) | hypothetical protein Mvan_3862 |
| M. vanbaalenii PYR-1 | Mvan_0309 | - | 2e-06 | 41.33% (75) | hypothetical protein Mvan_0309 |
| M. vanbaalenii PYR-1 | Mvan_3414 | - | 3e-06 | 27.56% (156) | hypothetical protein Mvan_3414 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0262c | PPE2 | 2e-06 | 42.47% (73) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_4819 | - | 1e-06 | 33.71% (89) | hypothetical protein Mflv_4819 |
| M. tuberculosis H37Rv | Rv0256c | PPE2 | 2e-06 | 42.47% (73) | PPE family protein |
| M. leprae Br4923 | MLBr_01828 | PPE | 7e-05 | 34.04% (94) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_2436 | - | 2e-06 | 60.00% (40) | hypothetical protein MAB_2436 |
| M. marinum M | MMAR_3242 | mmpS3 | 3e-06 | 32.52% (123) | membrane protein MmpS3 |
| M. avium 104 | MAV_1722 | - | 9e-08 | 60.53% (38) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_6551 | - | 1e-44 | 53.80% (171) | hypothetical protein MSMEG_6551 |
| M. thermoresistible (build 8) | TH_0510 | - | 6e-07 | 32.30% (161) | SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA |
| M. ulcerans Agy99 | MUL_3555 | mmpS3 | 2e-06 | 32.52% (123) | membrane protein MmpS3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0262c|M.bovis_AF2122/97 MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAA
Rv0256c|M.tuberculosis_H37Rv MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAA
MLBr_01828|M.leprae_Br4923 MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVA
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0510|M.thermoresistible__bu --------------------------------------------------
Mb0262c|M.bovis_AF2122/97 LLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMATRQETAATAY
Rv0256c|M.tuberculosis_H37Rv LLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMATRQETAATAY
MLBr_01828|M.leprae_Br4923 LLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAY
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M ------------------------------MSGPNPPGWEPDEPDPAGDS
MUL_3555|M.ulcerans_Agy99 ------------------------------MSGPNPPGWEPDEPDPAGDS
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 -----------------------------MQQPRATSAAKRTHRARVIAA
TH_0510|M.thermoresistible__bu -------------------------------VAAGLTGILGFAGSTASAQ
Mb0262c|M.bovis_AF2122/97 GTALAAMPTLAELGANHALHGVLMATNFFG-INTIPIALNESDYARMWIQ
Rv0256c|M.tuberculosis_H37Rv GTALAAMPTLAELGANHALHGVLMATNFFG-INTIPIALNESDYARMWIQ
MLBr_01828|M.leprae_Br4923 ITTLAMMPTLAELAANRTAHTVLVTTNFFG-INTIPIARNEIDYVRMWVE
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M SAELEPFGDTDDEPDDALAGGELEPVSESGQIEPVDPAQESEAYSRAYSA
MUL_3555|M.ulcerans_Agy99 SAELEPFGDTGDEPDDALAGGELEPVSESGQIEPVDPAQESEAYSRAYSA
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 TIAVTSLSGAGAYTLAATPVDQAPATVRTANIHLVTTDAPPPPAPPATPA
TH_0510|M.thermoresistible__bu PLVPQPPPPPAPATVTQTVTVAAAPVAPVAPVTPVGPVNRTP--------
Mb0262c|M.bovis_AF2122/97 AATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAASDEPN--------
Rv0256c|M.tuberculosis_H37Rv AATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAASDEPN--------
MLBr_01828|M.leprae_Br4923 AAIAMGTYQEVSTVVVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSP
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M PESEQ---------------------------------------------
MUL_3555|M.ulcerans_Agy99 PESEQ---------------------------------------------
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 P-------------------------------------------------
TH_0510|M.thermoresistible__bu --------------------------------------------------
Mb0262c|M.bovis_AF2122/97 QVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAMFSGFDPWLPSLG
Rv0256c|M.tuberculosis_H37Rv QVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAMFSGFDPWLPSLG
MLBr_01828|M.leprae_Br4923 QVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSGFDPWLPSLG
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M ---------------------------------FISGAYLPADLSLYDYD
MUL_3555|M.ulcerans_Agy99 ---------------------------------FISGAYLPADLSLYDYD
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 ----------------------------------GQPAPNPETPTTVTTP
TH_0510|M.thermoresistible__bu -------------------------------------------PVAVDPA
Mb0262c|M.bovis_AF2122/97 NPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFIGADLAAAFASGNPAT
Rv0256c|M.tuberculosis_H37Rv NPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFIGADLAAAFASGNPAT
MLBr_01828|M.leprae_Br4923 NPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFASGNPVT
Mvan_3862|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6551|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3242|M.marinum_M GYDDSLDEEDEPSTPRWPWVVG------------------VAAIMAAIAL
MUL_3555|M.ulcerans_Agy99 GYDDSLDEEDEPSTPRWPWVVG------------------VAAIMAAIAL
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2436|M.abscessus_ATCC_1997 PPAPAPGQPAPPTPPPAPGAPADGGRVNNDQGGFSFVVPQGWVQSDARRL
TH_0510|M.thermoresistible__bu TGVAIGTAPAAGTTPALPVAVPRETIVPARSGTLRDFFTERGVKMEPQAA
Mb0262c|M.bovis_AF2122/97 IAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPLLAAPLAPLT
Rv0256c|M.tuberculosis_H37Rv IAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPLLAAPLAPLT
MLBr_01828|M.leprae_Br4923 IGFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPLLTAPLA---
Mvan_3862|M.vanbaalenii_PYR-1 -----MLVGMSIAGPIVT--------------------------------
MSMEG_6551|M.smegmatis_MC2_155 -----MLVGMNIKGPIAT--------------------------------
MMAR_3242|M.marinum_M VASVSLLVTRTDSTKLAN--------------------------------
MUL_3555|M.ulcerans_Agy99 VASVSLLVTRTDSTKLAN--------------------------------
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --MRWLRILPAKAHCLLR--------------------------------
MAB_2436|M.abscessus_ATCC_1997 TYGSALLTNPAAPNGSIL--------------------------------
TH_0510|M.thermoresistible__bu DGFTALNIVLPMPRGWAHVP------------------------------
Mb0262c|M.bovis_AF2122/97 LAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVAAIAPSIP------TPT
Rv0256c|M.tuberculosis_H37Rv LAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVAAIAPSIP------TPT
MLBr_01828|M.leprae_Br4923 VATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASI
Mvan_3862|M.vanbaalenii_PYR-1 ------LGAVAALATGILLADLTLNPNPQP----PAPPS-----------
MSMEG_6551|M.smegmatis_MC2_155 ------IGAVAVVGTGLFLLNVSRQPEPTASGNTPAATSTA-------TA
MMAR_3242|M.marinum_M ------PATTSSVPPVQDEITTTKPPPPPPPPPPPPSTEIP------TAT
MUL_3555|M.ulcerans_Agy99 ------PATTSSVPPVQDEITTTKPPPPPPPPPPPPSTEIP------TAT
MAV_1722|M.avium_104 ------MGFDPNVPAAGPAPDAPPPPAPDAPP--APAPDAP-------PA
Mflv_4819|M.gilvum_PYR-GCK ------PDAVQMSRGPASRALYSKSACRCAGTYWAVGPRAVRVGCHNHHS
MAB_2436|M.abscessus_ATCC_1997 ------LGRLDLKLFAGAEPDNQKAARRLASDMGEFFMPYPGNRVNQEDQ
TH_0510|M.thermoresistible__bu -----DPNVPDAFAVIADRVGGGFYTSNAQVVVYKLIGDFD-------PK
Mb0262c|M.bovis_AF2122/97 PTPAPAPAPTAVTAPTPPPGPPPPPVTAPPPVTGAGIQSFGYLVGDLNSA
Rv0256c|M.tuberculosis_H37Rv PTPAPAPAPTAVTAPTPPPGPPPPPVTAPPPVTGAGIQSFGYLVGDLNSA
MLBr_01828|M.leprae_Br4923 PTPTPMPAPAASTAPVVTP-PGPPPVTAPPSVTGAGVESFGYLVGRLPST
Mvan_3862|M.vanbaalenii_PYR-1 PAAVAAPAPAAPVPPP-PVPPPPVPFGPQQDFVADISTKTGTLPLQIR--
MSMEG_6551|M.smegmatis_MC2_155 PTGTAAVSPAPAAPPATPTTPAPRPFADREDFVADIPTKTGNIALEIR--
MMAR_3242|M.marinum_M ETQTVTVTPPPPPPPPPETSAAPPPAATTPTTPAAAPPPTTTTPAGPRQV
MUL_3555|M.ulcerans_Agy99 ETQTVTVTPPPPPPPPPETSAAPPPAATTPTTPAAAPPPTTTTPAGPRQV
MAV_1722|M.avium_104 PDAPPPPAPDAPPPPAPDAPPAPGPDVPPPPAPKAYSVNWDAIAQCESGG
Mflv_4819|M.gilvum_PYR-GCK CLRISGVALRGSVIVASAAMFVAGALGVAPAGHAAVCGSVGGVHVDVSGC
MAB_2436|M.abscessus_ATCC_1997 SFDVAGMSAASSYYEVKFDDAAKEPGQIWAAAVGKGKDRWFIVWLGTAAS
TH_0510|M.thermoresistible__bu EAISHGYIDSLQLPAWRTTAQSMADHHGWPSSLIEGTYRDNSVTLNTSRR
Mb0262c|M.bovis_AF2122/97 AQARKAVGTGVRKKTPEPDSAEAPAAAAAPEEQVQPQRRRRPKIKQLGRG
Rv0256c|M.tuberculosis_H37Rv AQARKAVGTGVRKKTPEPDSAEAPAAAAAPEEQVQPQRRRRPKIKQLGRG
MLBr_01828|M.leprae_Br4923 ARG--VVGTSVRQQSSAPDRIEAPDAAATPQEQARSRWRRRAKVTPFDS-
Mvan_3862|M.vanbaalenii_PYR-1 -----VVGDTADAYACDNAGIETWLSGSAVGGVLKLTSTDRT--------
MSMEG_6551|M.smegmatis_MC2_155 -----VDGAKARAYACDNKGIETWMWGTAENGVLKLADQAKT--------
MMAR_3242|M.marinum_M TYS--VTGTKAPGDIISVTYVDASGRRRTQHNVYIPWSMTVT--------
MUL_3555|M.ulcerans_Agy99 TYS--VTGTKAPGDIISVTYVDASGRRRTQHNVYIPWSMTVT--------
MAV_1722|M.avium_104 NWGINTGNGYAGGLQFTSSTWHANGGSGSPAG------------------
Mflv_4819|M.gilvum_PYR-GCK ADPLYELNDALAPPPPPPPPPPPPPGAPPPPP------------------
MAB_2436|M.abscessus_ATCC_1997 PVDKGVAKALTESIRPWTPPTPPTPSAAPPADPNQPAPPPADPNQP----
TH_0510|M.thermoresistible__bu HVIATSGSDRYLVSLSVTTEVDQAVAAAEATDAIVNGFKVTS--------
Mb0262c|M.bovis_AF2122/97 YEYLDLDPETGHDPTGSPQGAGTLGFAGTTHKASPGQVAGLITLPNDAFG
Rv0256c|M.tuberculosis_H37Rv YEYLDLDPETGHDPTGSPQGAGTLGFAGTTHKASPGQVAGLITLPNDAFG
MLBr_01828|M.leprae_Br4923 ----SGSPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFS
Mvan_3862|M.vanbaalenii_PYR-1 ------ARLDGRHRDGTVVGTLWIGDRHWDFTAVPGATDAF---------
MSMEG_6551|M.smegmatis_MC2_155 ------SELNGTHQGNTVVGNLRINDKNWDFTAVPGATSVF---------
MMAR_3242|M.marinum_M --------PISQSDVGSVEASSLFRVSRLNCSITTSDGTVLSSNSNDAPQ
MUL_3555|M.ulcerans_Agy99 --------PISQSDVGSVEASSLFRVSRLNCSITTSDGTVLSSNSNDAPQ
MAV_1722|M.avium_104 ----------ASREEQIRVAENVLHSQGIGAWPVCGRRG-----------
Mflv_4819|M.gilvum_PYR-GCK ----------PPPPPPPPPVYIPPPLPNVNVCADVGRRINVSGCI-----
MAB_2436|M.abscessus_ATCC_1997 ------PPPPADPNQPPAPPAPTAPAAPAAEPAAPGQPAPPTPPAAPPAP
TH_0510|M.thermoresistible__bu ----------PTRPSAPPAPVRAPSAAPVSLPASGAGLPAAQP-------
.
Mb0262c|M.bovis_AF2122/97 GSPRTPMMPGTWDTDSATRVE-------------
Rv0256c|M.tuberculosis_H37Rv GSPRTPMMPGTWDTDSATRVE-------------
MLBr_01828|M.leprae_Br4923 DSPRAPMLPRTWGADPTFCYNAADIGPAGGWDDE
Mvan_3862|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_6551|M.smegmatis_MC2_155 ----------------------------------
MMAR_3242|M.marinum_M TSC-------------------------------
MUL_3555|M.ulcerans_Agy99 TSC-------------------------------
MAV_1722|M.avium_104 ----------------------------------
Mflv_4819|M.gilvum_PYR-GCK ----------------------------------
MAB_2436|M.abscessus_ATCC_1997 GVPV------------------------------
TH_0510|M.thermoresistible__bu ----------------------------------