For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0510 (-)

annotation: SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA ANTIGEN)
coordinates: 1090673 - 1091578
length: 302

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0510--100% (302)SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA ANTIGEN)
M. thermoresistible (build 8)TH_0908lpqT2e-1531.55% (168) PROBABLE CONSERVED LIPOPROTEIN LPQT
M. thermoresistible (build 8)TH_3241-1e-0525.73% (307) PUTATIVE putative FHA domain containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0041cmtc282e-8255.78% (303) secreted proline rich protein MTC28 (proline rich 28 kDa
M. gilvum PYR-GCKMflv_0852-1e-8357.00% (300) hypothetical protein Mflv_0852
M. tuberculosis H37RvRv0040cmtc282e-8255.78% (303) secreted proline rich protein MTC28 (proline rich 28 kDa
M. leprae Br4923MLBr_00031-6e-7253.17% (284) hypothetical protein MLBr_00031
M. abscessus ATCC 19977MAB_4924-1e-5540.59% (303) hypothetical protein MAB_4924
M. marinum MMMAR_0056mtc288e-8456.33% (316) secreted proline rich protein Mtc28
M. avium 104MAV_0054-3e-8154.13% (303) proline-rich 28 kDa antigen
M. smegmatis MC2 155MSMEG_6919-2e-8859.93% (297) proline-rich 28 kDa antigen
M. ulcerans Agy99MUL_0055mtc281e-8253.71% (337) secreted proline rich protein Mtc28
M. vanbaalenii PYR-1Mvan_6055-9e-9363.04% (303) hypothetical protein Mvan_6055

CLUSTAL 2.0.9 multiple sequence alignment


Mb0041c|M.bovis_AF2122/97           ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
Rv0040c|M.tuberculosis_H37Rv        ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
MMAR_0056|M.marinum_M               ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
MUL_0055|M.ulcerans_Agy99           ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
MLBr_00031|M.leprae_Br4923          ------------------MIQSTQTWRVLAG---GLAATAMGVTVFAGGT
MAV_0054|M.avium_104                ------------------MIEIVPGHRAVLG---GMVAGLIGLAVAAGGT
TH_0510|M.thermoresistible__bu      -----------------------------------VAAGLTGILGFAGST
MSMEG_6919|M.smegmatis_MC2_155      ------------------MTESARRWRVLS---AGVAAGLAGFVSLAGNT
Mflv_0852|M.gilvum_PYR-GCK          MDTFVAYRLTTWERTAPKMSESARHWRILAGGIGALAG-IAGVLGVTS-T
Mvan_6055|M.vanbaalenii_PYR-1       ------------------MSEIARHWRVLAGGIGACAAGVAGVLGVAAST
MAB_4924|M.abscessus_ATCC_1997      ------------------MTTTRYSVRFAAA-----TASVAALLAGTAAV
                                                                        .    ..   :.  

Mb0041c|M.bovis_AF2122/97           ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
Rv0040c|M.tuberculosis_H37Rv        ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
MMAR_0056|M.marinum_M               ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPVPA
MUL_0055|M.ulcerans_Agy99           ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPAPA
MLBr_00031|M.leprae_Br4923          AAADPSPPAP---PPAIPGVLPPASLPPIQSVTAVPGGITTNNRFVATPQ
MAV_0054|M.avium_104                ASADPLPPAPAPVPAPAPANLGPELVPPSRYLAAPQATTAATQITPATPG
TH_0510|M.thermoresistible__bu      ASAQPLVPQPPPPPAPATVTQTVTVAAAPVAPVAPVTPVGPVNRTPPVAV
MSMEG_6919|M.smegmatis_MC2_155      ASAEPVLPMPPAPVPSPVVQQAAPLAPAAAPAAAAVPGTSSLGVTNQTPG
Mflv_0852|M.gilvum_PYR-GCK          ASAQPAVPQPTVP-QPVIPQASIPQVSVPAPAAV-------------ASA
Mvan_6055|M.vanbaalenii_PYR-1       ASAQPMIPQPALP-APATVTQTVIVTPDTAPAALGQPGVTPA--TTGAAA
MAB_4924|M.abscessus_ATCC_1997      AMADPQ-PAPVPPVPAATANAAVAPAPNAAPAPAVAPTTS----------
                                    * *:*  * *     .          .                       

Mb0041c|M.bovis_AF2122/97           --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
Rv0040c|M.tuberculosis_H37Rv        --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
MMAR_0056|M.marinum_M               QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
MUL_0055|M.ulcerans_Agy99           QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
MLBr_00031|M.leprae_Br4923          -------------APGPAALG---------------------QPPLAVAA
MAV_0054|M.avium_104                -------TPGPAPAPAPAQAP---------------------APAPAPAP
TH_0510|M.thermoresistible__bu      DPATGVAIGTAPAAGTTPALP-------------------VAVPRETIVP
MSMEG_6919|M.smegmatis_MC2_155      VPAATVPTGTVP-TGAVPAAP-------------------AAVPQPAIVP
Mflv_0852|M.gilvum_PYR-GCK          VPAA--ANALPAAAPVAPAVP-------------------PAPRPPTIVP
Mvan_6055|M.vanbaalenii_PYR-1       VPAG--VSAG-VGAPAAPALP-------------------TRP-VSTIAP
MAB_4924|M.abscessus_ATCC_1997      ---------ANPLQPAAP--------------------------IAGVAP
                                                     .                              ..

Mb0041c|M.bovis_AF2122/97           AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
Rv0040c|M.tuberculosis_H37Rv        AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
MMAR_0056|M.marinum_M               AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
MUL_0055|M.ulcerans_Agy99           AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
MLBr_00031|M.leprae_Br4923          PVSESLHDYFKAKNIKLVAQKPHGFKALDITLPVPTRWTQVPDPNVPDAF
MAV_0054|M.avium_104                ATSGTIREFLQSKGVKFEAQKPQGFKALDITLPMPARWTQVPDPNVPDAF
TH_0510|M.thermoresistible__bu      ARSGTLRDFFTERGVKMEPQAADGFTALNIVLPMPRGWAHVPDPNVPDAF
MSMEG_6919|M.smegmatis_MC2_155      ATSGTLSEFLAEHGVKMEPQVADNFTALNIVLPMPTNWTKVPDPNVPNAF
Mflv_0852|M.gilvum_PYR-GCK          ATSGTLAEFFAAKGVTLEPQNSRDFRALNIVLPMPRGWELIPDPNVPNAF
Mvan_6055|M.vanbaalenii_PYR-1       ATSGTLAEFFAAKGVAMEPQSSRDFRALNIVLPKPRGWEHIPDPNVPDAF
MAB_4924|M.abscessus_ATCC_1997      AADGTLSEFFASKNVKVEPLTKSSHGVPRISIPIPNNWANVPDPNVPNAY
                                    .   :: :.:  :.: . .    .. .  * :* *  *  :******:*:

Mb0041c|M.bovis_AF2122/97           VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
Rv0040c|M.tuberculosis_H37Rv        VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
MMAR_0056|M.marinum_M               AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
MUL_0055|M.ulcerans_Agy99           AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
MLBr_00031|M.leprae_Br4923          AVIADRLG-NSLYTSNAQLVVYNLVGNFDPKEAITHGFVDTQQLSAWQTT
MAV_0054|M.avium_104                AVIADRHG-SSIYSSNAQVVVYKLVGNFDPREAITHGYVDSQKLPAWQPT
TH_0510|M.thermoresistible__bu      AVIADRVGG-GFYTSNAQVVVYKLIGDFDPKEAISHGYIDSLQLPAWRTT
MSMEG_6919|M.smegmatis_MC2_155      AVIADRTSK-DLYTPNAQVVVYKLIGDFDPRAAISHGYVDSQKLLGWRTT
Mflv_0852|M.gilvum_PYR-GCK          AVLADRVGGNGLYSSNAQVIVYKLIGQFDPREAISHGFVESQKLPAWRTT
Mvan_6055|M.vanbaalenii_PYR-1       AVLADRVGGNGLYSSNAQVVVYKLVGAFDPKEAISHGFIDSQKLPAWRST
MAB_4924|M.abscessus_ATCC_1997      QVIVSKANGTGIYQSNAQLTMSKLIGEFDTNEAVSHGPVEVKALQGWQPT
                                     *:..: .  ..* .***: : .*:* :*.  *::** ::   * .*:.*

Mb0041c|M.bovis_AF2122/97           NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
Rv0040c|M.tuberculosis_H37Rv        NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
MMAR_0056|M.marinum_M               NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
MUL_0055|M.ulcerans_Agy99           NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
MLBr_00031|M.leprae_Br4923          NASKADFDGFPSSIIEGTYRENGMTLNTSRRHVIASSGPDKYLVSLSVT-
MAV_0054|M.avium_104                NASMADFGGFPSSIVEGTYRDGDLTLNTSRRHVIATSGPDKYLVSLAVT-
TH_0510|M.thermoresistible__bu      AQSMADHHGWPSSLIEGTYRDNSVTLNTSRRHVIATSGSDRYLVSLSVT-
MSMEG_6919|M.smegmatis_MC2_155      DMAMGDFYGFPSSFIEGSYTEGSQVLNTSRRHVIATSGDDRYLVSLSVNW
Mflv_0852|M.gilvum_PYR-GCK          DASLAEFGGMPSSVIEGTYRENNMTLNTSRRNVIATVGPDNYLVSLAVT-
Mvan_6055|M.vanbaalenii_PYR-1       DASLADFGGMPSSLIEGTYRENNLTLNTSRRHVIATVGPDSYLVSLSVT-
MAB_4924|M.abscessus_ATCC_1997      DASLVTYQGFPSSIVEGTFRQDGETLNTSRRAVIITQGKDRFLVQLAVT-
                                      :   . * ***.:**:: :.. .****** ** : * : :**.*:*. 

Mb0041c|M.bovis_AF2122/97           TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
Rv0040c|M.tuberculosis_H37Rv        TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
MMAR_0056|M.marinum_M               TAQSQAV-ADAPATDAIINGFR------VAAPTAAGHTPARAGAPAAVAP
MUL_0055|M.ulcerans_Agy99           TAQSQAV-ADAPATDAIINGFR------VATPTAAGHTPARAGAATAVAP
MLBr_00031|M.leprae_Br4923          TALSQAV-ADAPATNAIVNGFR------VSSPTVSAPVPP----------
MAV_0054|M.avium_104                TDRAVAV-ADAPATDAIVNGFR------VTVPGASAPAPTAAP------V
TH_0510|M.thermoresistible__bu      TEVDQAV-AAAEATDAIVNGFK------VTSPTRP---------------
MSMEG_6919|M.smegmatis_MC2_155      SAANQGISAAADATDAIVSGFR------VSAPAPA---------------
Mflv_0852|M.gilvum_PYR-GCK          TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVMPLPGA-------
Mvan_6055|M.vanbaalenii_PYR-1       TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVAPLPGT-------
MAB_4924|M.abscessus_ATCC_1997      TTVGNAI-AEAPATDLIVNGLRFGDAAPVTAPVADPNALADPDAVPG---
                                    :     : : . **: *:.*::      *                     

Mb0041c|M.bovis_AF2122/97           ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
Rv0040c|M.tuberculosis_H37Rv        ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
MMAR_0056|M.marinum_M               QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPVPNLTPALQAVPGQVAA
MUL_0055|M.ulcerans_Agy99           QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPAPNLTPALQAVPGQVAA
MLBr_00031|M.leprae_Br4923          ----------QLGTR-----------------------------------
MAV_0054|M.avium_104                ALPAQAPAVAPVAPAPAPVAPAAPTAPAPAAAPLVPLAQTAPAAPAGLPA
TH_0510|M.thermoresistible__bu      ----------SAPPAPVRAPSAAPVSLPASGAGLPAAQP-----------
MSMEG_6919|M.smegmatis_MC2_155      ----------PAAPPAAPAP-VAPPALPALPQ-LPGLPG-----------
Mflv_0852|M.gilvum_PYR-GCK          ----------PALPLPAAAPQAPGAPAVAPPPQLLGLQG-----------
Mvan_6055|M.vanbaalenii_PYR-1       ----------PALPLASAPPPAPAVPTVAPAPQLLGLQG-----------
MAB_4924|M.abscessus_ATCC_1997      ------APATPAAGAPAAADPNAPASPAPGVPGLPPLPTLPALVPPAPPA
                                                                                      

Mb0041c|M.bovis_AF2122/97           -------PVPPR------------------
Rv0040c|M.tuberculosis_H37Rv        -------PVPPR------------------
MMAR_0056|M.marinum_M               APPVAAAPAPSR------------------
MUL_0055|M.ulcerans_Agy99           APPVAAAPAPSR------------------
MLBr_00031|M.leprae_Br4923          ------------------------------
MAV_0054|M.avium_104                QPLPNQQHTPSLLAMVPGLPPLPNFSFLQH
TH_0510|M.thermoresistible__bu      ------------------------------
MSMEG_6919|M.smegmatis_MC2_155      ------------------------------
Mflv_0852|M.gilvum_PYR-GCK          ------------------------------
Mvan_6055|M.vanbaalenii_PYR-1       ------------------------------
MAB_4924|M.abscessus_ATCC_1997      A-----------------------------