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M. vanbaalenii PYR-1 Mvan_3504 (-)

annotation: response regulator receiver/unknown domain-containing protein
coordinates: 3723301 - 3723966
length: 221

MRDVLVVDDDFMVADIHRRFVDRVDGFRAVGVARTGEEALTATKELRPQLILLDVYLPDMTGLDVLQRLR
AEGDRVDVIMITAARELDTVRGALDGGAADYLIKPFEFAQLQAKLQAFAARADALQSASGVDQTLIDTLF
GGPAVTPAKVLPKGLGAETGELVLAAVRGAGEVSAAECADAVGISRVSARRYLEHYLSVGALELRLQYGV
GRPERRYRIAG

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_3504 - - 100% (221) response regulator receiver/unknown domain-containing protein
M. vanbaalenii PYR-1 Mvan_4698 - 4e-31 34.80% (227) response regulator receiver/unknown domain-containing protein
M. vanbaalenii PYR-1 Mvan_1752 - 7e-17 43.86% (114) two component transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3274c mtrA 7e-18 43.33% (120) two component sensory transduction transcriptional
M. gilvum PYR-GCK Mflv_3002 - 1e-105 85.97% (221) response regulator receiver/unknown domain-containing protein
M. tuberculosis H37Rv Rv3246c mtrA 8e-18 43.33% (120) two component sensory transduction transcriptional
M. leprae Br4923 MLBr_00773 mtrA 3e-18 43.33% (120) putative two-component response regulator
M. abscessus ATCC 19977 MAB_3591c - 3e-18 40.60% (133) DNA-binding response regulator MtrA
M. marinum M MMAR_1299 mtrA 1e-17 43.33% (120) two-component sensory transduction transcriptional
M. avium 104 MAV_4209 - 9e-18 43.33% (120) DNA-binding response regulator MtrA
M. smegmatis MC2 155 MSMEG_4212 - 8e-96 80.82% (219) transcriptional regulatory protein CitT
M. thermoresistible (build 8) TH_4129 - 2e-17 43.86% (114) PUTATIVE DNA-binding response regulator MtrA
M. ulcerans Agy99 MUL_2582 mtrA 8e-18 43.33% (120) two component sensory transduction transcriptional

CLUSTAL 2.0.9 multiple sequence alignment


Mb3274c|M.bovis_AF2122/97           -------MDTMRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
Rv3246c|M.tuberculosis_H37Rv        -------MDTMRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
MAV_4209|M.avium_104                -------MDSMRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
MLBr_00773|M.leprae_Br4923          -------MDIMRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
MMAR_1299|M.marinum_M               ----------MRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
MUL_2582|M.ulcerans_Agy99           -------MDTMRQRILVVDDDASLAEMLT-IVLRGEGFDTAVIG-DGTQA
TH_4129|M.thermoresistible__bu      LSRFGDNMDTMRQRILVVDDDPSLAEMLT-IVLRGEGFDTAVIG-DGSQA
MAB_3591c|M.abscessus_ATCC_199      ----------MRQRILVVDDDASLAEMLT-IVLRGEGFETAVVS-DGTQA
Mvan_3504|M.vanbaalenii_PYR-1       -----------MRDVLVVDDDFMVADIHRRFVDRVDGFRAVGVARTGEEA
Mflv_3002|M.gilvum_PYR-GCK          -----------MRDVLVVDDDFMVAEIHRRFVDRIDGFRVVGVARTGAEA
MSMEG_4212|M.smegmatis_MC2_155      -----------MRDVLVVDDDFMVAEIHRRFVDRVDGFRAVGVARTGAEA
                                                : :******  :*::   :* * :** .. :.  * :*

Mb3274c|M.bovis_AF2122/97           LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
Rv3246c|M.tuberculosis_H37Rv        LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
MAV_4209|M.avium_104                LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
MLBr_00773|M.leprae_Br4923          LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
MMAR_1299|M.marinum_M               LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
MUL_2582|M.ulcerans_Agy99           LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKTDTVD
TH_4129|M.thermoresistible__bu      LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSG-VPIVMLTAKSDTVD
MAB_3591c|M.abscessus_ATCC_199      LTAVRELRPDLVLLDLMLPGMNGIDVCRVLRSDSG-VPIVMLTAKTDTVD
Mvan_3504|M.vanbaalenii_PYR-1       LTATKELRPQLILLDVYLPDMTGLDVLQRLRAEGDRVDVIMITAARELDT
Mflv_3002|M.gilvum_PYR-GCK          LEATRQLRPQLILLDVYLPDMTGLEVLQQLRSGGDRVDVIVITAARELDT
MSMEG_4212|M.smegmatis_MC2_155      MASADALRPDLILLDVYLPDMTGLEVLKRLRADGNLVGVIMITAARELDT
                                    : :.  ***:*:***: **.*.*::* : **: .. * ::::**  :   

Mb3274c|M.bovis_AF2122/97           VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVEID
Rv3246c|M.tuberculosis_H37Rv        VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVEID
MAV_4209|M.avium_104                VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVEID
MLBr_00773|M.leprae_Br4923          VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVDID
MMAR_1299|M.marinum_M               VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVDID
MUL_2582|M.ulcerans_Agy99           VVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-EPAEMLSIADVDID
TH_4129|M.thermoresistible__bu      VVLGLESGADDYVVKPFKPKELVARVRARLRRNED-EPAEMLSIGDIDID
MAB_3591c|M.abscessus_ATCC_199      VVLGLESGADDYIMKPFKPKELVARIRARLRRNDD-EPAELLNIAGIDID
Mvan_3504|M.vanbaalenii_PYR-1       VRGALDGGAADYLIKPFEFAQLQAKLQAFAARADALQSASGVDQTLIDTL
Mflv_3002|M.gilvum_PYR-GCK          VRGALDGGAADYLIKPFEFSQLETKLTAYAARADALQSARGADQDLIDAL
MSMEG_4212|M.smegmatis_MC2_155      VRGALDGGAADYLIKPFEFDQLRAKLVAFAARADALAADGGADQSMIDAL
                                    *  .*:.** **::***:  :* ::: *   * :   .    .   ::  

Mb3274c|M.bovis_AF2122/97           VPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
Rv3246c|M.tuberculosis_H37Rv        VPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MAV_4209|M.avium_104                VPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MLBr_00773|M.leprae_Br4923          VPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MMAR_1299|M.marinum_M               VPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MUL_2582|M.ulcerans_Agy99           VPAHKATRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
TH_4129|M.thermoresistible__bu      VPAHKVTRNGEQIQLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
MAB_3591c|M.abscessus_ATCC_199      VPAHKVTREGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPA
Mvan_3504|M.vanbaalenii_PYR-1       FGGPAVTPAKVLPKGLGAETGELVLAAVRGAGEVSAAECADAVGISRVSA
Mflv_3002|M.gilvum_PYR-GCK          FGGPSVAPAKTMPKGLGAETGELVLDAVRTAGEVSAAECADLVGISRVSA
MSMEG_4212|M.smegmatis_MC2_155      FGGSAPTATAALPKGLGAETGRLVMDAVRNAGEVSAAQCAELVGISRVSA
                                    . .   :      .    * . **  * :    .:     : *   * .*

Mb3274c|M.bovis_AF2122/97           DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Rv3246c|M.tuberculosis_H37Rv        DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
MAV_4209|M.avium_104                DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
MLBr_00773|M.leprae_Br4923          DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
MMAR_1299|M.marinum_M               DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
MUL_2582|M.ulcerans_Agy99           DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
TH_4129|M.thermoresistible__bu      DTRLVN-VHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
MAB_3591c|M.abscessus_ATCC_199      DTRLVN-VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Mvan_3504|M.vanbaalenii_PYR-1       RRYLEHYLSVGALELRLQYGVGRPERRYRIAG--------
Mflv_3002|M.gilvum_PYR-GCK          RRYLEHYLGTGTLELRLQYGVGRPERRYRIAG--------
MSMEG_4212|M.smegmatis_MC2_155      RRYLEHFLSTGALELRLQYGTGRPERRYRIP---------
                                       * : : .  *. ::: .  .*     :

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_3504	-	-	100% (221)	response regulator receiver/unknown domain-containing protein
M. vanbaalenii PYR-1	Mvan_4698	-	4e-31	34.80% (227)	response regulator receiver/unknown domain-containing protein
M. vanbaalenii PYR-1	Mvan_1752	-	7e-17	43.86% (114)	two component transcriptional regulator