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TAALLVDSVTVHYGPVLALDRATLSLQAGRVCGLVGMNGSGKSTLFKTIIGLVRPDTGRVLINGGTPAQA RRAGHVGYLPQSEDIDWTFPLSVRDVVLTGRYGHMGPARRARKSDHEAVDTALSRVELDGYQHRQIGQLS GGQRKRAFLARCITQGADLLLLDEPFAGVDKRSEATISRVLRDLAAAGATILIATHDLHALPDLADEAIL LMRTVLMHDRPATVLQPQNLARAFGFDVAGES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3370 | - | - | 100% (243) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_5326 | - | 3e-31 | 38.03% (213) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_5319 | - | 2e-30 | 34.60% (237) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-26 | 35.91% (220) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3167 | - | 1e-102 | 77.97% (236) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-26 | 35.91% (220) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01892 | - | 7e-22 | 31.47% (232) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1655 | - | 7e-24 | 33.62% (235) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 1e-24 | 35.02% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-23 | 36.24% (218) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_6046 | - | 4e-30 | 34.60% (237) | cation ABC transporter, ATP-binding protein, putative |
| M. thermoresistible (build 8) | TH_4530 | - | 1e-81 | 63.60% (239) | PUTATIVE ABC transporter-related protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-24 | 35.02% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3370|M.vanbaalenii_PYR-1 ------MT--------AALLVDSVTVHYGPVLALDRATLSLQAGRVCGLV
Mflv_3167|M.gilvum_PYR-GCK ------MTTAA-----PALQVESLTVRYGPVLALDDASFTLHPGRVCGLV
TH_4530|M.thermoresistible__bu ------MT--------FAIEVADVTVRYGEVVALRDISARVRRGTVCGLI
MSMEG_6046|M.smegmatis_MC2_155 --MSSHNAETE-----PALVFDDVSVVRGGRLIWSEGTFTIPSGGIVALI
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTALL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTALL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYGDFVALDHVDFVVPTGSLTALL
MMAR_3715|M.marinum_M MKKETSLTGPG--TGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MUL_3658|M.ulcerans_Agy99 ------MTGPG--TGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MAB_1655|M.abscessus_ATCC_1997 ------MTAEN------TITVRGANKHYGDFAALDNIDFDVPSGSLTALL
MLBr_01892|M.leprae_Br4923 ------MPMG------VAIEVKGLTKSFGSSRIWEDVTLDIPAGEVSVLL
. :: . . * : * : *:
Mvan_3370|M.vanbaalenii_PYR-1 GMNGSGKSTLFKTIIGLVRPDTGRVLING-GTPAQARRAGHVGYLPQSED
Mflv_3167|M.gilvum_PYR-GCK GMNGSGKSTLFKAIMGLVRSDTGDVRIHD-SSPARARRAGVVGYMPQSEA
TH_4530|M.thermoresistible__bu GMNGSGKSTLFKTIVGLVRPDTGRVLLDG-DPPAVARKRGAISYVPQSEQ
MSMEG_6046|M.smegmatis_MC2_155 GSNGSGKSTMLQVILGLLPVASGSVRVLD-GRPGEHN--DQIGYVPQDYV
Mb2419c|M.bovis_AF2122/97 GPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY-
Rv2397c|M.tuberculosis_H37Rv GPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY-
MAV_1785|M.avium_104 GPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHY-
MMAR_3715|M.marinum_M GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY-
MUL_3658|M.ulcerans_Agy99 GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY-
MAB_1655|M.abscessus_ATCC_1997 GPSGSGKSTLLRSIAGLDNPDSGTITINGRDVTGVPPQRRDIGFVFQHY-
MLBr_01892|M.leprae_Br4923 GPSGTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFGVL
* .*:***.::: : ** * : : . .
Mvan_3370|M.vanbaalenii_PYR-1 IDWTFPLSVRDVVLTGRYGHMGPARRARKSDHEAVDTALSRVELDGYQHR
Mflv_3167|M.gilvum_PYR-GCK IDWTFPLSVRDVVMTGRYGHMGPARRARHVDRRAVDDALARVELSDFRHR
TH_4530|M.thermoresistible__bu IDWSFPLSIHDVVMTGRYGHQGFTRRPRAADRAAVAAALDRVGLTDLARR
MSMEG_6046|M.smegmatis_MC2_155 AGAGEAIRARDAVTLGLTGHRWGMRRVTAEEKARVDQALAAVEATEFADR
Mb2419c|M.bovis_AF2122/97 -AAFKHLTVRDNVAFG----LKIRKRPKAEIKAKVDNLLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv -AAFKHLTVRDNVAFG----LKIRKRPKAEIKAKVDNLLQVVGLSGFQSR
MAV_1785|M.avium_104 -AAFKHLTVRDNVAYG----LKVRKRPKAEIKAKVDNLLEVVGLSGFQGR
MMAR_3715|M.marinum_M -AAFKHLTVRDNVAYG----LKIRKRPKAEIRDKVDNLLEVVGLSGFHGR
MUL_3658|M.ulcerans_Agy99 -AAFKHLTVRDNVAYG----LKIRKRPKAEIRDKVDNLLEVVGLSGFHGR
MAB_1655|M.abscessus_ATCC_1997 -AAFKHLTVWENVAFG----LKIRKKPKAEIKKKVDDLLEVVGLSGFHTR
MLBr_01892|M.leprae_Br4923 FQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLQLVGLGGDEKK
: : :: : * * * :
Mvan_3370|M.vanbaalenii_PYR-1 QIGQLSGGQRKRAFLARCITQGADLLLLDEPFAGVDKRSEATISRVLRDL
Mflv_3167|M.gilvum_PYR-GCK QIGRLSGGQRKRAFLARCLAQGAELLLLDEPFAGVDKRSEATICRLLRDL
TH_4530|M.thermoresistible__bu QIGQASGGQRKRAFVARAIAQEADILLLDEPFAGVDTRTETALIALLRQL
MSMEG_6046|M.smegmatis_MC2_155 RVSQLSGGQRQRIALANALVAHPRMLILDEPLAALDLRSQHEIVQLLARV
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MAV_1785|M.avium_104 YPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MAB_1655|M.abscessus_ATCC_1997 YPAQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRL
MLBr_01892|M.leprae_Br4923 FPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDI
. *** *:* :*..:. . ::: *** ..:* : : :
Mvan_3370|M.vanbaalenii_PYR-1 AAAG-ATILIATHDLHALPDLADEAILLMRTVLMHDR-PATVLQPQN---
Mflv_3167|M.gilvum_PYR-GCK ADSG-ATVLIATHDLNALPELADEAILLMRTVLLHDH-PDTVLDPRN---
TH_4530|M.thermoresistible__bu AADG-KTVLVSTHDLRSLPTLADEVILLMRRVLAQGD-PETVLAPDN---
MSMEG_6046|M.smegmatis_MC2_155 NSEYQVTIIVVAHDLNPLLSVLDSAIYLLDG-HAHHA-PMDVVNADL---
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MAV_1785|M.avium_104 HDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
MAB_1655|M.abscessus_ATCC_1997 HDEVHVTTVLVTHDQAEALDVADRIAVLNKGRIEQVGSPEDLYDRPANSF
MLBr_01892|M.leprae_Br4923 NAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFG-PREVLLTSDEPV
* :: :*: : * * * :
Mvan_3370|M.vanbaalenii_PYR-1 --------------LARAFGFDVAGES-----------------------
Mflv_3167|M.gilvum_PYR-GCK --------------LARAFGLDLPRSRGGQ--------------------
TH_4530|M.thermoresistible__bu --------------LARAFGQDVLSRR-----------------------
MSMEG_6046|M.smegmatis_MC2_155 --------------LTHLYGTKVQVANTLQGQMYMRSE------------
Mb2419c|M.bovis_AF2122/97 VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
Rv2397c|M.tuberculosis_H37Rv VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
MAV_1785|M.avium_104 VMSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDR
MMAR_3715|M.marinum_M VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
MUL_3658|M.ulcerans_Agy99 VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
MAB_1655|M.abscessus_ATCC_1997 VMSFLGPVAKLNGILVRPHDIRVGRNADLARAAAEGTGETTGVTKATVDR
MLBr_01892|M.leprae_Br4923 VRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAEEVEGVPPQI
: . .
Mvan_3370|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3167|M.gilvum_PYR-GCK --------------------------------------------------
TH_4530|M.thermoresistible__bu --------------------------------------------------
MSMEG_6046|M.smegmatis_MC2_155 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
Rv2397c|M.tuberculosis_H37Rv VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
MAV_1785|M.avium_104 VVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDTVYVRATRVPP
MMAR_3715|M.marinum_M IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPP
MUL_3658|M.ulcerans_Agy99 IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPP
MAB_1655|M.abscessus_ATCC_1997 VVYLGFEVRVELTSAATGEQFTAQITRGDAEALGLREGDPVYVRVTRVP-
MLBr_01892|M.leprae_Br4923 TVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGAHNYQAHEFG
Mvan_3370|M.vanbaalenii_PYR-1 ------------------------------
Mflv_3167|M.gilvum_PYR-GCK ------------------------------
TH_4530|M.thermoresistible__bu ------------------------------
MSMEG_6046|M.smegmatis_MC2_155 ------------------------------
Mb2419c|M.bovis_AF2122/97 IAGG---VSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv IAGG---VSGVDDAGVERVKVTST------
MAV_1785|M.avium_104 ITAGATTVPAVSRDGADEATLTSA------
MMAR_3715|M.marinum_M IAGA---APAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 IAGA---APAVPDDGAGSTPRAAQIGVGGQ
MAB_1655|M.abscessus_ATCC_1997 -------------DVGELAEVAS-------
MLBr_01892|M.leprae_Br4923 D-----------------------------