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TTAAPALQVESLTVRYGPVLALDDASFTLHPGRVCGLVGMNGSGKSTLFKAIMGLVRSDTGDVRIHDSSP ARARRAGVVGYMPQSEAIDWTFPLSVRDVVMTGRYGHMGPARRARHVDRRAVDDALARVELSDFRHRQIG RLSGGQRKRAFLARCLAQGAELLLLDEPFAGVDKRSEATICRLLRDLADSGATVLIATHDLNALPELADE AILLMRTVLLHDHPDTVLDPRNLARAFGLDLPRSRGGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3167 | - | - | 100% (249) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_1455 | - | 8e-30 | 33.89% (239) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2681 | - | 6e-25 | 35.29% (221) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 4e-25 | 36.41% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 4e-25 | 36.41% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00590 | - | 2e-20 | 29.77% (215) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_0548c | - | 7e-24 | 31.84% (223) | putative iron compound ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 7e-24 | 35.29% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 3e-24 | 35.94% (217) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_6046 | - | 1e-33 | 37.05% (224) | cation ABC transporter, ATP-binding protein, putative |
| M. thermoresistible (build 8) | TH_4530 | - | 2e-79 | 63.14% (236) | PUTATIVE ABC transporter-related protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-24 | 35.29% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3370 | - | 1e-102 | 77.97% (236) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3167|M.gilvum_PYR-GCK -----------MTTAAPALQVESLTVRYGPVLALDDASFTLHPGRVCGLV
Mvan_3370|M.vanbaalenii_PYR-1 -----------MT---AALLVDSVTVHYGPVLALDRATLSLQAGRVCGLV
TH_4530|M.thermoresistible__bu -----------MT---FAIEVADVTVRYGEVVALRDISARVRRGTVCGLI
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTALL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTALL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYGDFVALDHVDFVVPTGSLTALL
MSMEG_6046|M.smegmatis_MC2_155 -------MSSHNAETEPALVFDDVSVVRGGRLIWSEGTFTIPSGGIVALI
MAB_0548c|M.abscessus_ATCC_199 ----------------MDVTFRNVSVSIAGAQIISDIHLNVAAGGFVGIV
MLBr_00590|M.leprae_Br4923 ----MSSACTVPETPEVVIRLRGVCKHYGSILAVSNLDLDIHSAEVLALL
: . . . : . . .::
Mflv_3167|M.gilvum_PYR-GCK GMNGSGKSTLFKAIMGLVRSDTGDVRIHDSSPARARR-AGVVGYMPQSEA
Mvan_3370|M.vanbaalenii_PYR-1 GMNGSGKSTLFKTIIGLVRPDTGRVLINGGTPAQARR-AGHVGYLPQSED
TH_4530|M.thermoresistible__bu GMNGSGKSTLFKTIVGLVRPDTGRVLLDGDPPAVARK-RGAISYVPQSEQ
Mb2419c|M.bovis_AF2122/97 GPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYA
Rv2397c|M.tuberculosis_H37Rv GPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYA
MMAR_3715|M.marinum_M GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYA
MUL_3658|M.ulcerans_Agy99 GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYA
MAV_1785|M.avium_104 GPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHYA
MSMEG_6046|M.smegmatis_MC2_155 GSNGSGKSTMLQVILGLLPVASGSVRVLDG---RPGEHNDQIGYVPQDYV
MAB_0548c|M.abscessus_ATCC_199 GPNGSGKSTTLRCLYRALTPASGDVAVNGVSVRAISMRENARQVAALTQD
MLBr_00590|M.leprae_Br4923 GPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQGG
* .*:**:* .. :* : : .
Mflv_3167|M.gilvum_PYR-GCK IDWTFPLSVRDVVMTGRYGHMGPARRARHVDRRAVDDALARVELSDFRHR
Mvan_3370|M.vanbaalenii_PYR-1 IDWTFPLSVRDVVLTGRYGHMGPARRARKSDHEAVDTALSRVELDGYQHR
TH_4530|M.thermoresistible__bu IDWSFPLSIHDVVMTGRYGHQGFTRRPRAADRAAVAAALDRVGLTDLARR
Mb2419c|M.bovis_AF2122/97 AFKHLTVRDNVAFGLKIR------KRPKAEIKAKVDNLLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv AFKHLTVRDNVAFGLKIR------KRPKAEIKAKVDNLLQVVGLSGFQSR
MMAR_3715|M.marinum_M AFKHLTVRDNVAYGLKIR------KRPKAEIRDKVDNLLEVVGLSGFHGR
MUL_3658|M.ulcerans_Agy99 AFKHLTVRDNVAYGLKIR------KRPKAEIRDKVDNLLEVVGLSGFHGR
MAV_1785|M.avium_104 AFKHLTVRDNVAYGLKVR------KRPKAEIKAKVDNLLEVVGLSGFQGR
MSMEG_6046|M.smegmatis_MC2_155 AGAGEAIRARDAVTLGLTGHRWGMRRVTAEEKARVDQALAAVEATEFADR
MAB_0548c|M.abscessus_ATCC_199 MSLDFDFTAAEVIATGRLPHGASLRGTSQLDRQICARATETADVTALSGR
MLBr_00590|M.leprae_Br4923 GGYPAARAGEMLNLVASY----------AADPLDPEWLLETLGLTDVART
Mflv_3167|M.gilvum_PYR-GCK QIGRLSGGQRKRAFLARCLAQGAELLLLDEPFAGVDKRSEATICRLLRDL
Mvan_3370|M.vanbaalenii_PYR-1 QIGQLSGGQRKRAFLARCITQGADLLLLDEPFAGVDKRSEATISRVLRDL
TH_4530|M.thermoresistible__bu QIGQASGGQRKRAFVARAIAQEADILLLDEPFAGVDTRTETALIALLRQL
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MAV_1785|M.avium_104 YPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRL
MSMEG_6046|M.smegmatis_MC2_155 RVSQLSGGQRQRIALANALVAHPRMLILDEPLAALDLRSQHEIVQLLARV
MAB_0548c|M.abscessus_ATCC_199 TFGSLSGGERQRVLIARALAQQPHVLVLDEPTNHLDVRHQYSILNSAR--
MLBr_00590|M.leprae_Br4923 TYRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTL
***:::* :* :. . ::.**** :* : . :
Mflv_3167|M.gilvum_PYR-GCK ADSG-ATVLIATHDLNALPELADEAILLMRT-------------------
Mvan_3370|M.vanbaalenii_PYR-1 AAAG-ATILIATHDLHALPDLADEAILLMRT-------------------
TH_4530|M.thermoresistible__bu AADG-KTVLVSTHDLRSLPTLADEVILLMRR-------------------
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
MAV_1785|M.avium_104 HDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAF
MSMEG_6046|M.smegmatis_MC2_155 NSEYQVTIIVVAHDLNPLLSVLDSAIYLLDG-------------------
MAB_0548c|M.abscessus_ATCC_199 --ALGITVIAALHDLNLAAQYCDTIHVMADGN------------------
MLBr_00590|M.leprae_Br4923 RRDG-VTVVLTTHQLKEAEELADRLVIIDHGR------------------
* : *: * :
Mflv_3167|M.gilvum_PYR-GCK ---------------------VLLHDHPDTVLDPRN--------------
Mvan_3370|M.vanbaalenii_PYR-1 ---------------------VLMHDRPATVLQPQN--------------
TH_4530|M.thermoresistible__bu ---------------------VLAQGDPETVLAPDN--------------
Mb2419c|M.bovis_AF2122/97 VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
Rv2397c|M.tuberculosis_H37Rv VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
MMAR_3715|M.marinum_M VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
MUL_3658|M.ulcerans_Agy99 VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
MAV_1785|M.avium_104 VMSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDR
MSMEG_6046|M.smegmatis_MC2_155 ----------------------HAHHAPMDVVNAD---------------
MAB_0548c|M.abscessus_ATCC_199 ---------------------VVLSGSPHEVLTAES--------------
MLBr_00590|M.leprae_Br4923 ---------------------MIAAGTPTELMHTGAKDQLRFSAPPRLDL
:
Mflv_3167|M.gilvum_PYR-GCK --LARAFGLDLPRSRGGQ--------------------------------
Mvan_3370|M.vanbaalenii_PYR-1 --LARAFGFDVAGES-----------------------------------
TH_4530|M.thermoresistible__bu --LARAFGQDVLSRR-----------------------------------
Mb2419c|M.bovis_AF2122/97 -VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
Rv2397c|M.tuberculosis_H37Rv -VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
MMAR_3715|M.marinum_M -IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVP
MUL_3658|M.ulcerans_Agy99 -IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVP
MAV_1785|M.avium_104 -VVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDTVYVRATRVP
MSMEG_6046|M.smegmatis_MC2_155 -LLTHLYGTKVQVANTLQG---------------------QMYMRSE---
MAB_0548c|M.abscessus_ATCC_199 --VGRWFGIDCHVITHPRSGVPQVIFYAEPERQEKQ--------------
MLBr_00590|M.leprae_Br4923 SLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINVLTTNMR
:
Mflv_3167|M.gilvum_PYR-GCK -------------------------------
Mvan_3370|M.vanbaalenii_PYR-1 -------------------------------
TH_4530|M.thermoresistible__bu -------------------------------
Mb2419c|M.bovis_AF2122/97 PIAG---GVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv PIAG---GVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M PIAG---AAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 PIAG---AAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 PITAGATTVPAVSRDGADEATLTSA------
MSMEG_6046|M.smegmatis_MC2_155 -------------------------------
MAB_0548c|M.abscessus_ATCC_199 -------------------------------
MLBr_00590|M.leprae_Br4923 VEQHSLEDVFLDLTGRKLR------------