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M. vanbaalenii PYR-1 Mvan_3323 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 3536940 - 3538184
length: 414

MLEWSDVDIAVRDAVREFVDKEVRPHLDALESGEMEPYPIIRKLFATFGIADMARESLNKRLDRLRDGTE
SPGKSAGGGMFGGGGSPGMGFVVISELCRVSMGVVTGMGVSLGLTVPTIMSRGTLAQQERWLPDLVTYDK
IGAWAITEPDSGSDAFGGMKSYVTRDGDDYILNGQKTFITNGPDADVVVVYAKLDEGDPSIDKRDRKVLT
FVLDKGMDGFVQSKPFRKMGIHSSRTGELFFNDVRLGRDRLLGETEDNSGGDGRDSARSNFSAERIGVAA
MSLGVIEECLRLCVDYAKSRTLWGKEIAQFQLIQLKLATMEVARMNVRNMLFRVIEAAQTGTPISLAEAS
AIKWYCSQAATDVAMEAVQVFGGNGYMTEYRVEQLARDAKSLMIYAGSNEVQITHVARGLLSQP

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_3323 - - 100% (414) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_2342 - e-157 66.59% (416) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4205 - 3e-51 32.84% (402) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2812c fadE21 1e-156 67.39% (414) acyl-CoA dehydrogenase FADE21
M. gilvum PYR-GCK Mflv_3537 - 0.0 86.75% (415) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv2789c fadE21 1e-156 67.39% (414) acyl-CoA dehydrogenase FADE21
M. leprae Br4923 MLBr_00737 fadE25 8e-41 29.53% (403) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_2395 - 0.0 76.89% (424) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_1919 fadE21 1e-154 66.59% (413) acyl-CoA dehydrogenase FadE21
M. avium 104 MAV_3680 - 1e-167 70.74% (417) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_3783 - 0.0 89.08% (412) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4655 - 0.0 86.65% (412) PUTATIVE acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2144 fadE21 1e-153 66.10% (413) acyl-CoA dehydrogenase FadE21

CLUSTAL 2.0.9 multiple sequence alignment


Mb2812c|M.bovis_AF2122/97           -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
Rv2789c|M.tuberculosis_H37Rv        -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
MMAR_1919|M.marinum_M               -MIEWSDTDLMMRDAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MUL_2144|M.ulcerans_Agy99           -MIEWSDTDLMMRGAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MAV_3680|M.avium_104                -MIEWSDTDLMVRDAVRQFVDKEIRPHLDELESGAMSPYPIARKLFSQFG
Mflv_3537|M.gilvum_PYR-GCK          -MLDWSDVDIAVRDAVREFVDKEIRPHLDELESGDMEPYPIVRKLFATFG
MSMEG_3783|M.smegmatis_MC2_155      MMLDWSDVDVAVRDAVREFVDKEIRPHLDELESGDMEPYPIIRKLFSTFG
TH_4655|M.thermoresistible__bu      -MLDWSDVDLAVRDAVREFIDKEIRPHLDELESGDMEPYPIVRKLFATFG
Mvan_3323|M.vanbaalenii_PYR-1       -MLEWSDVDIAVRDAVREFVDKEVRPHLDALESGEMEPYPIIRKLFATFG
MAB_2395|M.abscessus_ATCC_1997      -MLDWSPIDLAVRDAVRQFIDKEVRPHVDALESGEMEPYPIIRKMFATFG
MLBr_00737|M.leprae_Br4923          -MVGWSGNPLFDLFKLPEEHN-ELRATIRALAEKEIAPHAADVDQRARFP
                                     *. **   :     : :  : *:*.    *    : *:.   .  : * 

Mb2812c|M.bovis_AF2122/97           LDVLLAESVNQMLDGERA------KR-EKRD-----SSGSF----GLADQ
Rv2789c|M.tuberculosis_H37Rv        LDVLLAESVNQMLDGERA------KR-EKRD-----SSGSF----GLADQ
MMAR_1919|M.marinum_M               LDVLAAESVKSILDAERA------DQGEKRHR----TSGSG----GLGPQ
MUL_2144|M.ulcerans_Agy99           LDVLAAESVKSILDAERA------NQDEKRHR----TSGSG----GLGPQ
MAV_3680|M.avium_104                LDTMAAEAVKKMLDRERS------GADENGD-----SSGAANEFSGGGAQ
Mflv_3537|M.gilvum_PYR-GCK          IDAMAKEALDKRLARMRE------GGEKPSKS----GGGGMF---GGG-S
MSMEG_3783|M.smegmatis_MC2_155      IDTMAKEALDKRLARLRA------GEDKPGKS----SGGGMF---GGG-S
TH_4655|M.thermoresistible__bu      IDKMAKEALDKRLARLRE------GGEAKTAG----SRGGMF---GGG-S
Mvan_3323|M.vanbaalenii_PYR-1       IADMARESLNKRLDRLRD------GTESPGKS----AGGGMF---GGGGS
MAB_2395|M.abscessus_ATCC_1997      IDALAKEGLQKQIEKKKAREAALAAGEQPAESKKSDGGGAMG---LAGGS
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVP----------EEYG-------------GQGAD
                                       :     .                                     . .

Mb2812c|M.bovis_AF2122/97           ASMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLV
Rv2789c|M.tuberculosis_H37Rv        ASMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLV
MMAR_1919|M.marinum_M               ASMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELM
MUL_2144|M.ulcerans_Agy99           ASMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELM
MAV_3680|M.avium_104                GSMIAVLVSEIARVSIGLLSTASVSLGLGAATIASRGTLAQKERWLPELM
Mflv_3537|M.gilvum_PYR-GCK          AGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQGRGTLAQQERWLPGLV
MSMEG_3783|M.smegmatis_MC2_155      PGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLV
TH_4655|M.thermoresistible__bu      PGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLV
Mvan_3323|M.vanbaalenii_PYR-1       PGMGFVVISELCRVSMGVVTGMGVSLGLTVPTIMSRGTLAQQERWLPDLV
MAB_2395|M.abscessus_ATCC_1997      AGMGFVLTSEISRVCMGLVTGMGVSMGLTVPTIASRGTAAQMECWLPELV
MLBr_00737|M.leprae_Br4923          SVAACIVIEEVARVDASASLIPAVNK-LGTMGLILRGSEELKKQVLPSLA
                                         :: .*:. *  .     .*.  * .  :  **:    :  :* * 

Mb2812c|M.bovis_AF2122/97           TLEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGP
Rv2789c|M.tuberculosis_H37Rv        TLEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGP
MMAR_1919|M.marinum_M               TLEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGP
MUL_2144|M.ulcerans_Agy99           TLEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGP
MAV_3680|M.avium_104                TLEKIAAWAITEPDSGSDAFGGMKTSVRRSGDGDGAYILNGQKTFITNGP
Mflv_3537|M.gilvum_PYR-GCK          TYEKIGAWAITEPDSGSDAFGGMKSWVARAADGSGDYILNGQKTFITNGP
MSMEG_3783|M.smegmatis_MC2_155      TYEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGP
TH_4655|M.thermoresistible__bu      TYEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGP
Mvan_3323|M.vanbaalenii_PYR-1       TYDKIGAWAITEPDSGSDAFGGMKSYVTRDGD---DYILNGQKTFITNGP
MAB_2395|M.abscessus_ATCC_1997      TYEKVGAWAITEPDSGSDAFGGMKTYVTRDGE---DYILNGQKTFITNGP
MLBr_00737|M.leprae_Br4923          AEGAMASYALSEREAGSDAAS-MRTRAKADGDD---WILNGFKCWITNGG
                                    :   :.::*::* ::**** . *:: .   .     :**** * :**** 

Mb2812c|M.bovis_AF2122/97           YADVLVVYAKLAD--GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGM
Rv2789c|M.tuberculosis_H37Rv        YADVLVVYAKLAD--GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGM
MMAR_1919|M.marinum_M               YADVLLVYAKLDEA-GATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGM
MUL_2144|M.ulcerans_Agy99           YADVLLVYAKLDEA-GATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGM
MAV_3680|M.avium_104                YADVLVVYAKLDE--GDPSVDKRNRSVLVFVLDAGMPGLTQGKPFKKMGM
Mflv_3537|M.gilvum_PYR-GCK          DADVVVVYAKLDE----PGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGI
MSMEG_3783|M.smegmatis_MC2_155      DADVVVVYAKLDEG---DGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGI
TH_4655|M.thermoresistible__bu      DADVVVVYAKLDE----PGVAPRDRKVLTFVLDKGMEGFVQSRPFRKMGI
Mvan_3323|M.vanbaalenii_PYR-1       DADVVVVYAKLDEGD--PSIDKRDRKVLTFVLDKGMDGFVQSKPFRKMGI
MAB_2395|M.abscessus_ATCC_1997      DADVIVVYAKLNEGAGKDSVDPRDRKVLTFVLDKGMEGFTQSKPFRKMGI
MLBr_00737|M.leprae_Br4923          KSTWYTVMAVTDP-------DKGANGISAFIVHKDDEGFSIGPKEKKLGI
                                     :    * *               . :  *::. .  *:  .   :*:*:

Mb2812c|M.bovis_AF2122/97           MSSPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALM
Rv2789c|M.tuberculosis_H37Rv        MSSPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALM
MMAR_1919|M.marinum_M               MSSPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALM
MUL_2144|M.ulcerans_Agy99           MSSPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALM
MAV_3680|M.avium_104                MSSPTGELFFDNVRLTPDRLLGESEQHTEGDGRDSARANFAAERIGIAMM
Mflv_3537|M.gilvum_PYR-GCK          HSSRTGELFFNNVRLGRDRLLGETENNEAGDGRDSARSSFSAERIGVAAM
MSMEG_3783|M.smegmatis_MC2_155      HSSRTGELFFNNVRLGRDRLLGETEDHGAGDGRDSARSSFSAERIGVAAM
TH_4655|M.thermoresistible__bu      HSSRTGELFFNNVRLGRDRLLGESEDQ-AGDGRDSARSSFSAERIGVAAM
Mvan_3323|M.vanbaalenii_PYR-1       HSSRTGELFFNDVRLGRDRLLGETEDNSGGDGRDSARSNFSAERIGVAAM
MAB_2395|M.abscessus_ATCC_1997      HSSRTGQLFFENVRLGKDRLLGETETNDQGDGRDSARANFSMERIGVAAL
MLBr_00737|M.leprae_Br4923          KGSPTTELYFDKCRIPGDRIIGEP-----GTGFKTALATLDHTRPTIGAQ
                                     .* * :*:*:. *:  **::        * * .:* :.:   *  :.  

Mb2812c|M.bovis_AF2122/97           SLGIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMV
Rv2789c|M.tuberculosis_H37Rv        SLGIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMV
MMAR_1919|M.marinum_M               ALGIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMV
MUL_2144|M.ulcerans_Agy99           ALGIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMV
MAV_3680|M.avium_104                ALGIIDECHRLCVDYAKSRTLWGKNIGQFQLIQLKLAKMEIARMNVQNMV
Mflv_3537|M.gilvum_PYR-GCK          ALGVIEECLRLSVDYAKTRKLWGQEIGQFQLIQLKLATMEVARMNVRNML
MSMEG_3783|M.smegmatis_MC2_155      ALGVIEECLRLSVDYAKSRKLWGQEIGQFQLIQLKLANMEVARMNVRNML
TH_4655|M.thermoresistible__bu      ALGVIEECLRLCVDYAKNRKLWGQEIAQFQLIQLKLAKMEVARMNVRNML
Mvan_3323|M.vanbaalenii_PYR-1       SLGVIEECLRLCVDYAKSRTLWGKEIAQFQLIQLKLATMEVARMNVRNML
MAB_2395|M.abscessus_ATCC_1997      ALGVIEECLRLSLDYAKSRTLWGKEIAQFQLIQLKLAKMEVARLNVRNML
MLBr_00737|M.leprae_Br4923          AVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIV
                                    ::*: : .   .: *:* *. :*..*. ** **: ** * :    .. ::

Mb2812c|M.bovis_AF2122/97           FQAIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
Rv2789c|M.tuberculosis_H37Rv        FQAIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MMAR_1919|M.marinum_M               FQTLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MUL_2144|M.ulcerans_Agy99           FQTLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MAV_3680|M.avium_104                FHTIERQQAGKPLTLAEASAIKLYSSEAATEVAMEAVQLFGGNGYMAEYR
Mflv_3537|M.gilvum_PYR-GCK          FRVIESSQSGAPISLAEASAIKWYCSQAATDVAMDAIQLFGGNGYMTEYR
MSMEG_3783|M.smegmatis_MC2_155      FRVIESSQEGKPISLAEASAIKWYCSQAATDVAMDAVQLFGGNGYMTEYR
TH_4655|M.thermoresistible__bu      FRVIEAAEKGVPISLAEASAIKWYCSEAATDVAMDAVQLFGGNGYMTEYR
Mvan_3323|M.vanbaalenii_PYR-1       FRVIEAAQTGTPISLAEASAIKWYCSQAATDVAMEAVQVFGGNGYMTEYR
MAB_2395|M.abscessus_ATCC_1997      FHAIESLSENKTPSLAEASAIKLYCSEAATDVAMDAVQLFGGNGYMTEYR
MLBr_00737|M.leprae_Br4923          YAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFP
                                    : .    . .       ::* * :.*: * :*: :*:*:*** ** ::: 

Mb2812c|M.bovis_AF2122/97           VEQLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
Rv2789c|M.tuberculosis_H37Rv        VEQLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
MMAR_1919|M.marinum_M               VEQLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MUL_2144|M.ulcerans_Agy99           VEQLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MAV_3680|M.avium_104                VEQLARDAKSLMIYAGSNEVQVTHIAKGLLSS-----
Mflv_3537|M.gilvum_PYR-GCK          VEQLARDAKSLMIYAGSNEVQITHVARGLLSS-----
MSMEG_3783|M.smegmatis_MC2_155      VEQLARDAKSLMIYAGSNEVQITHVARGLLS------
TH_4655|M.thermoresistible__bu      VEQLARDAKSLMIYAGSNEVQITHVARGLLNA-----
Mvan_3323|M.vanbaalenii_PYR-1       VEQLARDAKSLMIYAGSNEVQITHVARGLLSQP----
MAB_2395|M.abscessus_ATCC_1997      VEQLARDAKSLMIYAGSNEVQITHIAKGLLADKAR--
MLBr_00737|M.leprae_Br4923          VERFMRDAKITQIYEGTNQIQRVVMSRALLR------
                                    **:: ****   ** *:*::* . :::.**

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_3323	-	-	100% (414)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_2342	-	e-157	66.59% (416)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4205	-	3e-51	32.84% (402)	acyl-CoA dehydrogenase domain-containing protein