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VMLDWSDVDVAVRDAVREFVDKEIRPHLDELESGDMEPYPIIRKLFSTFGIDTMAKEALDKRLARLRAGE DKPGKSSGGGMFGGGSPGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLVTYEK IGAWAITEPDSGSDAFGGMKSYVVRDGDDYILNGQKTFITNGPDADVVVVYAKLDEGDGVDKRDRKVLTF VLDKGMEGFVQSKPFRKMGIHSSRTGELFFNNVRLGRDRLLGETEDHGAGDGRDSARSSFSAERIGVAAM ALGVIEECLRLSVDYAKSRKLWGQEIGQFQLIQLKLANMEVARMNVRNMLFRVIESSQEGKPISLAEASA IKWYCSQAATDVAMDAVQLFGGNGYMTEYRVEQLARDAKSLMIYAGSNEVQITHVARGLLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3783 | - | - | 100% (411) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-48 | 32.36% (411) | long-chain specific acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0108 | - | 7e-47 | 32.06% (393) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2812c | fadE21 | 1e-150 | 66.83% (410) | acyl-CoA dehydrogenase FADE21 |
| M. gilvum PYR-GCK | Mflv_3537 | - | 0.0 | 92.98% (413) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2789c | fadE21 | 1e-150 | 66.83% (410) | acyl-CoA dehydrogenase FADE21 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 2e-42 | 30.27% (403) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2395 | - | 0.0 | 79.01% (424) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_1919 | fadE21 | 1e-155 | 67.31% (413) | acyl-CoA dehydrogenase FadE21 |
| M. avium 104 | MAV_3680 | - | 1e-166 | 72.66% (417) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4655 | - | 0.0 | 91.95% (410) | PUTATIVE acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2144 | fadE21 | 1e-155 | 66.67% (411) | acyl-CoA dehydrogenase FadE21 |
| M. vanbaalenii PYR-1 | Mvan_3323 | - | 0.0 | 89.08% (412) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2812c|M.bovis_AF2122/97 -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
Rv2789c|M.tuberculosis_H37Rv -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
MMAR_1919|M.marinum_M -MIEWSDTDLMMRDAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MUL_2144|M.ulcerans_Agy99 -MIEWSDTDLMMRGAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MAV_3680|M.avium_104 -MIEWSDTDLMVRDAVRQFVDKEIRPHLDELESGAMSPYPIARKLFSQFG
MSMEG_3783|M.smegmatis_MC2_155 MMLDWSDVDVAVRDAVREFVDKEIRPHLDELESGDMEPYPIIRKLFSTFG
Mflv_3537|M.gilvum_PYR-GCK -MLDWSDVDIAVRDAVREFVDKEIRPHLDELESGDMEPYPIVRKLFATFG
TH_4655|M.thermoresistible__bu -MLDWSDVDLAVRDAVREFIDKEIRPHLDELESGDMEPYPIVRKLFATFG
Mvan_3323|M.vanbaalenii_PYR-1 -MLEWSDVDIAVRDAVREFVDKEVRPHLDALESGEMEPYPIIRKLFATFG
MAB_2395|M.abscessus_ATCC_1997 -MLDWSPIDLAVRDAVRQFIDKEVRPHVDALESGEMEPYPIIRKMFATFG
MLBr_00737|M.leprae_Br4923 -MVGWSGNPLFDLFKLPEEHN-ELRATIRALAEKEIAPHAADVDQRARFP
*. ** : : : : *:*. * : *:. . : *
Mb2812c|M.bovis_AF2122/97 LDVLLAESVNQMLDGERA------KR-EKRD-----SSGSF----GLADQ
Rv2789c|M.tuberculosis_H37Rv LDVLLAESVNQMLDGERA------KR-EKRD-----SSGSF----GLADQ
MMAR_1919|M.marinum_M LDVLAAESVKSILDAERA------DQGEKRHR----TSGSG----GLGPQ
MUL_2144|M.ulcerans_Agy99 LDVLAAESVKSILDAERA------NQDEKRHR----TSGSG----GLGPQ
MAV_3680|M.avium_104 LDTMAAEAVKKMLDRERS------GADENGD-----SSGAANEFSGGGAQ
MSMEG_3783|M.smegmatis_MC2_155 IDTMAKEALDKRLARLRA------GEDKPGKS----SGGGMF---GGG-S
Mflv_3537|M.gilvum_PYR-GCK IDAMAKEALDKRLARMRE------GGEKPSKS----GGGGMF---GGG-S
TH_4655|M.thermoresistible__bu IDKMAKEALDKRLARLRE------GGEAKTAG----SRGGMF---GGG-S
Mvan_3323|M.vanbaalenii_PYR-1 IADMARESLNKRLDRLRD------GTESPGKS----AGGGMF---GGGGS
MAB_2395|M.abscessus_ATCC_1997 IDALAKEGLQKQIEKKKAREAALAAGEQPAESKKSDGGGAMG---LAGGS
MLBr_00737|M.leprae_Br4923 EEALAALNASGFNAIHVP----------EEYG-------------GQGAD
: . . .
Mb2812c|M.bovis_AF2122/97 ASMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLV
Rv2789c|M.tuberculosis_H37Rv ASMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLV
MMAR_1919|M.marinum_M ASMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELM
MUL_2144|M.ulcerans_Agy99 ASMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELM
MAV_3680|M.avium_104 GSMIAVLVSEIARVSIGLLSTASVSLGLGAATIASRGTLAQKERWLPELM
MSMEG_3783|M.smegmatis_MC2_155 PGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLV
Mflv_3537|M.gilvum_PYR-GCK AGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQGRGTLAQQERWLPGLV
TH_4655|M.thermoresistible__bu PGMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLV
Mvan_3323|M.vanbaalenii_PYR-1 PGMGFVVISELCRVSMGVVTGMGVSLGLTVPTIMSRGTLAQQERWLPDLV
MAB_2395|M.abscessus_ATCC_1997 AGMGFVLTSEISRVCMGLVTGMGVSMGLTVPTIASRGTAAQMECWLPELV
MLBr_00737|M.leprae_Br4923 SVAACIVIEEVARVDASASLIPAVNK-LGTMGLILRGSEELKKQVLPSLA
:: .*:. * . .*. * . : **: : :* *
Mb2812c|M.bovis_AF2122/97 TLEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGP
Rv2789c|M.tuberculosis_H37Rv TLEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGP
MMAR_1919|M.marinum_M TLEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGP
MUL_2144|M.ulcerans_Agy99 TLEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGP
MAV_3680|M.avium_104 TLEKIAAWAITEPDSGSDAFGGMKTSVRRSGDGDGAYILNGQKTFITNGP
MSMEG_3783|M.smegmatis_MC2_155 TYEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGP
Mflv_3537|M.gilvum_PYR-GCK TYEKIGAWAITEPDSGSDAFGGMKSWVARAADGSGDYILNGQKTFITNGP
TH_4655|M.thermoresistible__bu TYEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGP
Mvan_3323|M.vanbaalenii_PYR-1 TYDKIGAWAITEPDSGSDAFGGMKSYVTRDGD---DYILNGQKTFITNGP
MAB_2395|M.abscessus_ATCC_1997 TYEKVGAWAITEPDSGSDAFGGMKTYVTRDGE---DYILNGQKTFITNGP
MLBr_00737|M.leprae_Br4923 AEGAMASYALSEREAGSDAAS-MRTRAKADGDD---WILNGFKCWITNGG
: :.::*::* ::**** . *:: . . :**** * :****
Mb2812c|M.bovis_AF2122/97 YADVLVVYAKLAD--GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGM
Rv2789c|M.tuberculosis_H37Rv YADVLVVYAKLAD--GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGM
MMAR_1919|M.marinum_M YADVLLVYAKLDEA-GATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGM
MUL_2144|M.ulcerans_Agy99 YADVLLVYAKLDEA-GATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGM
MAV_3680|M.avium_104 YADVLVVYAKLDE--GDPSVDKRNRSVLVFVLDAGMPGLTQGKPFKKMGM
MSMEG_3783|M.smegmatis_MC2_155 DADVVVVYAKLDEG---DGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGI
Mflv_3537|M.gilvum_PYR-GCK DADVVVVYAKLDE----PGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGI
TH_4655|M.thermoresistible__bu DADVVVVYAKLDE----PGVAPRDRKVLTFVLDKGMEGFVQSRPFRKMGI
Mvan_3323|M.vanbaalenii_PYR-1 DADVVVVYAKLDEGD--PSIDKRDRKVLTFVLDKGMDGFVQSKPFRKMGI
MAB_2395|M.abscessus_ATCC_1997 DADVIVVYAKLNEGAGKDSVDPRDRKVLTFVLDKGMEGFTQSKPFRKMGI
MLBr_00737|M.leprae_Br4923 KSTWYTVMAVTDP-------DKGANGISAFIVHKDDEGFSIGPKEKKLGI
: * * . : *::. . *: . :*:*:
Mb2812c|M.bovis_AF2122/97 MSSPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALM
Rv2789c|M.tuberculosis_H37Rv MSSPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALM
MMAR_1919|M.marinum_M MSSPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALM
MUL_2144|M.ulcerans_Agy99 MSSPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALM
MAV_3680|M.avium_104 MSSPTGELFFDNVRLTPDRLLGESEQHTEGDGRDSARANFAAERIGIAMM
MSMEG_3783|M.smegmatis_MC2_155 HSSRTGELFFNNVRLGRDRLLGETEDHGAGDGRDSARSSFSAERIGVAAM
Mflv_3537|M.gilvum_PYR-GCK HSSRTGELFFNNVRLGRDRLLGETENNEAGDGRDSARSSFSAERIGVAAM
TH_4655|M.thermoresistible__bu HSSRTGELFFNNVRLGRDRLLGESEDQ-AGDGRDSARSSFSAERIGVAAM
Mvan_3323|M.vanbaalenii_PYR-1 HSSRTGELFFNDVRLGRDRLLGETEDNSGGDGRDSARSNFSAERIGVAAM
MAB_2395|M.abscessus_ATCC_1997 HSSRTGQLFFENVRLGKDRLLGETETNDQGDGRDSARANFSMERIGVAAL
MLBr_00737|M.leprae_Br4923 KGSPTTELYFDKCRIPGDRIIGEP-----GTGFKTALATLDHTRPTIGAQ
.* * :*:*:. *: **:: * * .:* :.: * :.
Mb2812c|M.bovis_AF2122/97 SLGIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMV
Rv2789c|M.tuberculosis_H37Rv SLGIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMV
MMAR_1919|M.marinum_M ALGIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMV
MUL_2144|M.ulcerans_Agy99 ALGIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMV
MAV_3680|M.avium_104 ALGIIDECHRLCVDYAKSRTLWGKNIGQFQLIQLKLAKMEIARMNVQNMV
MSMEG_3783|M.smegmatis_MC2_155 ALGVIEECLRLSVDYAKSRKLWGQEIGQFQLIQLKLANMEVARMNVRNML
Mflv_3537|M.gilvum_PYR-GCK ALGVIEECLRLSVDYAKTRKLWGQEIGQFQLIQLKLATMEVARMNVRNML
TH_4655|M.thermoresistible__bu ALGVIEECLRLCVDYAKNRKLWGQEIAQFQLIQLKLAKMEVARMNVRNML
Mvan_3323|M.vanbaalenii_PYR-1 SLGVIEECLRLCVDYAKSRTLWGKEIAQFQLIQLKLATMEVARMNVRNML
MAB_2395|M.abscessus_ATCC_1997 ALGVIEECLRLSLDYAKSRTLWGKEIAQFQLIQLKLAKMEVARLNVRNML
MLBr_00737|M.leprae_Br4923 AVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIV
::*: : . .: *:* *. :*..*. ** **: ** * : .. ::
Mb2812c|M.bovis_AF2122/97 FQAIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
Rv2789c|M.tuberculosis_H37Rv FQAIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MMAR_1919|M.marinum_M FQTLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MUL_2144|M.ulcerans_Agy99 FQTLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYR
MAV_3680|M.avium_104 FHTIERQQAGKPLTLAEASAIKLYSSEAATEVAMEAVQLFGGNGYMAEYR
MSMEG_3783|M.smegmatis_MC2_155 FRVIESSQEGKPISLAEASAIKWYCSQAATDVAMDAVQLFGGNGYMTEYR
Mflv_3537|M.gilvum_PYR-GCK FRVIESSQSGAPISLAEASAIKWYCSQAATDVAMDAIQLFGGNGYMTEYR
TH_4655|M.thermoresistible__bu FRVIEAAEKGVPISLAEASAIKWYCSEAATDVAMDAVQLFGGNGYMTEYR
Mvan_3323|M.vanbaalenii_PYR-1 FRVIEAAQTGTPISLAEASAIKWYCSQAATDVAMEAVQVFGGNGYMTEYR
MAB_2395|M.abscessus_ATCC_1997 FHAIESLSENKTPSLAEASAIKLYCSEAATDVAMDAVQLFGGNGYMTEYR
MLBr_00737|M.leprae_Br4923 YAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFP
: . . . ::* * :.*: * :*: :*:*:*** ** :::
Mb2812c|M.bovis_AF2122/97 VEQLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
Rv2789c|M.tuberculosis_H37Rv VEQLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
MMAR_1919|M.marinum_M VEQLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MUL_2144|M.ulcerans_Agy99 VEQLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MAV_3680|M.avium_104 VEQLARDAKSLMIYAGSNEVQVTHIAKGLLSS-----
MSMEG_3783|M.smegmatis_MC2_155 VEQLARDAKSLMIYAGSNEVQITHVARGLLS------
Mflv_3537|M.gilvum_PYR-GCK VEQLARDAKSLMIYAGSNEVQITHVARGLLSS-----
TH_4655|M.thermoresistible__bu VEQLARDAKSLMIYAGSNEVQITHVARGLLNA-----
Mvan_3323|M.vanbaalenii_PYR-1 VEQLARDAKSLMIYAGSNEVQITHVARGLLSQP----
MAB_2395|M.abscessus_ATCC_1997 VEQLARDAKSLMIYAGSNEVQITHIAKGLLADKAR--
MLBr_00737|M.leprae_Br4923 VERFMRDAKITQIYEGTNQIQRVVMSRALLR------
**:: **** ** *:*::* . :::.**