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M. vanbaalenii PYR-1 Mvan_2342 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 2500466 - 2501722
length: 418

VYEWSDTDIIMRDTVREFIATEIRPHLDDLESGALSPYPIARKLFSEFGLDAVAADAVKSMLDKERARHE
SGSTGEKHEKKAGGGLGDIGAQASMAAVLVSEIAGVSIGLLSTIGVSLGLGAATIMSRGTLAQKERWLPE
LMTLEKIAAWAITEPDAGSDAFGGMKTYVKRDGADYILNGQKTFITNGPDADVLVVYAKLADDPATDPRQ
RPVLTFVLDSGMAGLTQGRPFKKMGMMSSPTGELFFDNVRLSPDRLLGETEQHGAGDGRDSARANFAAER
LGIALMSLGIINECHRLCLDYAKTRTLWGRNIGQFQLIQLKLARIEVARMNVQNMVFQTLERLGAGRMPS
LAEASAIKLYSSEAATEAAMEAVQLFGGNGYMAEYRVEQLARDAKSLMIYAGSNEIQVTHIAKGLLSG

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_2342 - - 100% (418) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_3323 - e-157 66.59% (416) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4205 - 3e-46 31.68% (404) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2812c fadE21 0.0 78.66% (417) acyl-CoA dehydrogenase FADE21
M. gilvum PYR-GCK Mflv_3537 - 1e-155 67.70% (418) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv2789c fadE21 0.0 78.66% (417) acyl-CoA dehydrogenase FADE21
M. leprae Br4923 MLBr_00737 fadE25 1e-42 32.20% (410) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_2947c - 0.0 81.19% (420) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_1919 fadE21 0.0 81.97% (416) acyl-CoA dehydrogenase FadE21
M. avium 104 MAV_3680 - 0.0 79.05% (420) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_3783 - 1e-158 67.71% (415) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4655 - 1e-154 67.15% (417) PUTATIVE acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2144 fadE21 0.0 81.49% (416) acyl-CoA dehydrogenase FadE21

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3537|M.gilvum_PYR-GCK          -MLDWSDVDIAVRDAVREFVDKEIRPHLDELESGDMEPYPIVRKLFATFG
MSMEG_3783|M.smegmatis_MC2_155      MMLDWSDVDVAVRDAVREFVDKEIRPHLDELESGDMEPYPIIRKLFSTFG
TH_4655|M.thermoresistible__bu      -MLDWSDVDLAVRDAVREFIDKEIRPHLDELESGDMEPYPIVRKLFATFG
Mb2812c|M.bovis_AF2122/97           -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
Rv2789c|M.tuberculosis_H37Rv        -MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFG
MMAR_1919|M.marinum_M               -MIEWSDTDLMMRDAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MUL_2144|M.ulcerans_Agy99           -MIEWSDTDLMMRGAVRQFIDREIRPNLDELETGALSPYPIMRKLFSQFG
MAV_3680|M.avium_104                -MIEWSDTDLMVRDAVRQFVDKEIRPHLDELESGAMSPYPIARKLFSQFG
Mvan_2342|M.vanbaalenii_PYR-1       -MYEWSDTDIIMRDTVREFIATEIRPHLDDLESGALSPYPIARKLFSEFG
MAB_2947c|M.abscessus_ATCC_199      -MIEWSESDELIRESVREFIDKEVEPHRDGLESGELSPYPIARTLFSEFG
MLBr_00737|M.leprae_Br4923          -MVGWSGNPLFDLFKLPEEHN-ELRATIRALAEKEIAPHAADVDQRARFP
                                     *  **         : :    *:..    *    : *:.      : * 

Mflv_3537|M.gilvum_PYR-GCK          IDAMAKEALDKRLARMREGGE---------KPSKSGGGGMFG----GGSA
MSMEG_3783|M.smegmatis_MC2_155      IDTMAKEALDKRLARLRAGED---------KPGKSSGGGMFG----GGSP
TH_4655|M.thermoresistible__bu      IDKMAKEALDKRLARLREGGE---------AKTAGSRGGMFG----GGSP
Mb2812c|M.bovis_AF2122/97           LDVLLAESVNQMLDGERAKR----------EKRD-SSGSF----GLADQA
Rv2789c|M.tuberculosis_H37Rv        LDVLLAESVNQMLDGERAKR----------EKRD-SSGSF----GLADQA
MMAR_1919|M.marinum_M               LDVLAAESVKSILDAERADQG---------EKRHRTSGSG----GLGPQA
MUL_2144|M.ulcerans_Agy99           LDVLAAESVKSILDAERANQD---------EKRHRTSGSG----GLGPQA
MAV_3680|M.avium_104                LDTMAAEAVKKMLDRERSGAD---------ENGD-SSGAANEFSGGGAQG
Mvan_2342|M.vanbaalenii_PYR-1       LDAVAADAVKSMLDKERARHESGSTGEKHEKKAG---GGLG---DIGAQA
MAB_2947c|M.abscessus_ATCC_199      LDVVAAEAIKTILDKERLKAAAIAAGEPKPEKRGGASGGLG---DLAGQV
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYG----------------------GQGADS
                                     : :     .                                    . . 

Mflv_3537|M.gilvum_PYR-GCK          GMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQGRGTLAQQERWLPGLVT
MSMEG_3783|M.smegmatis_MC2_155      GMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLVT
TH_4655|M.thermoresistible__bu      GMGFVLISELCRVSMGLVTGMGVSLGLTVPTIQSRGTLAQQERWLPGLVT
Mb2812c|M.bovis_AF2122/97           SMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLVT
Rv2789c|M.tuberculosis_H37Rv        SMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLVT
MMAR_1919|M.marinum_M               SMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELMT
MUL_2144|M.ulcerans_Agy99           SMAAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQKQRWLPELMT
MAV_3680|M.avium_104                SMIAVLVSEIARVSIGLLSTASVSLGLGAATIASRGTLAQKERWLPELMT
Mvan_2342|M.vanbaalenii_PYR-1       SMAAVLVSEIAGVSIGLLSTIGVSLGLGAATIMSRGTLAQKERWLPELMT
MAB_2947c|M.abscessus_ATCC_199      SMAAVLVSELAGVSIGLLSTIGVSIGLGAATIMSRGTLAQKERWLPELVT
MLBr_00737|M.leprae_Br4923          VAACIVIEEVARVDASASLIPAVNK-LGTMGLILRGSEELKKQVLPSLAA
                                        :::.*:. *. .     .*.  * .  :  **:   ::: :* * :

Mflv_3537|M.gilvum_PYR-GCK          YEKIGAWAITEPDSGSDAFGGMKSWVARAADGSGDYILNGQKTFITNGPD
MSMEG_3783|M.smegmatis_MC2_155      YEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGPD
TH_4655|M.thermoresistible__bu      YEKIGAWAITEPDSGSDAFGGMKSYVVRDGD---DYILNGQKTFITNGPD
Mb2812c|M.bovis_AF2122/97           LEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGPY
Rv2789c|M.tuberculosis_H37Rv        LEKIAAWAITEPDSGSDAFGGMKTHVTRDGED---YILNGHKTFITNGPY
MMAR_1919|M.marinum_M               LEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGPY
MUL_2144|M.ulcerans_Agy99           LEKIAAWAITEPDSGSDAFGGMKTHVKRDGAD---YILNGQKTFITNGPY
MAV_3680|M.avium_104                LEKIAAWAITEPDSGSDAFGGMKTSVRRSGDGDGAYILNGQKTFITNGPY
Mvan_2342|M.vanbaalenii_PYR-1       LEKIAAWAITEPDAGSDAFGGMKTYVKRDGAD---YILNGQKTFITNGPD
MAB_2947c|M.abscessus_ATCC_199      LEKIACWAITEPDAGSDAFGGMKTYVKRDGAD---YILNGQKTFITNGPD
MLBr_00737|M.leprae_Br4923          EGAMASYALSEREAGSDAAS-MRTRAKADGDD---WILNGFKCWITNGGK
                                       :..:*::* ::**** . *:: .   .     :**** * :****  

Mflv_3537|M.gilvum_PYR-GCK          ADVVVVYAKLDE---PGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGIHS
MSMEG_3783|M.smegmatis_MC2_155      ADVVVVYAKLDE--GDGVDKRDRKVLTFVLDKGMEGFVQSKPFRKMGIHS
TH_4655|M.thermoresistible__bu      ADVVVVYAKLDE---PGVAPRDRKVLTFVLDKGMEGFVQSRPFRKMGIHS
Mb2812c|M.bovis_AF2122/97           ADVLVVYAKLAD-GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGMMS
Rv2789c|M.tuberculosis_H37Rv        ADVLVVYAKLAD-GEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGMMS
MMAR_1919|M.marinum_M               ADVLLVYAKLDEAGATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGMMS
MUL_2144|M.ulcerans_Agy99           ADVLLVYAKLDEAGATSSDRRDRPVLIFVLESGMAGLTQGKPFKKMGMMS
MAV_3680|M.avium_104                ADVLVVYAKLDE-GDPSVDKRNRSVLVFVLDAGMPGLTQGKPFKKMGMMS
Mvan_2342|M.vanbaalenii_PYR-1       ADVLVVYAKL-A-DDPATDPRQRPVLTFVLDSGMAGLTQGRPFKKMGMMS
MAB_2947c|M.abscessus_ATCC_199      ADVLIVYAKLDE-DDPTMDRRNRKVLTFVLDSGMPGLTQGKAFKKMGMMS
MLBr_00737|M.leprae_Br4923          STWYTVMAVTDP------DKGANGISAFIVHKDDEGFSIGPKEKKLGIKG
                                    :    * *              . :  *::. .  *:  .   :*:*: .

Mflv_3537|M.gilvum_PYR-GCK          SRTGELFFNNVRLGRDRLLGETENNEAGDGRDSARSSFSAERIGVAAMAL
MSMEG_3783|M.smegmatis_MC2_155      SRTGELFFNNVRLGRDRLLGETEDHGAGDGRDSARSSFSAERIGVAAMAL
TH_4655|M.thermoresistible__bu      SRTGELFFNNVRLGRDRLLGESEDQ-AGDGRDSARSSFSAERIGVAAMAL
Mb2812c|M.bovis_AF2122/97           SPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALMSL
Rv2789c|M.tuberculosis_H37Rv        SPTGELFFDNVRLTPDRLLCAE-----GDGRDSARANFAVERLGVALMSL
MMAR_1919|M.marinum_M               SPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALMAL
MUL_2144|M.ulcerans_Agy99           SPTGELFFDNVRLTPDRLLGESEHHGDGDGRESARANFAVERLGVALMAL
MAV_3680|M.avium_104                SPTGELFFDNVRLTPDRLLGESEQHTEGDGRDSARANFAAERIGIAMMAL
Mvan_2342|M.vanbaalenii_PYR-1       SPTGELFFDNVRLSPDRLLGETEQHGAGDGRDSARANFAAERLGIALMSL
MAB_2947c|M.abscessus_ATCC_199      SPTGELFFDNVRITADRLLGETEEHGGGDGRESARANFAAERVGVSLMAL
MLBr_00737|M.leprae_Br4923          SPTTELYFDKCRIPGDRIIGEP-----GTGFKTALATLDHTRPTIGAQAV
                                    * * **:*:: *:  **::        * * .:* :.:   *  :.  ::

Mflv_3537|M.gilvum_PYR-GCK          GVIEECLRLSVDYAKTRKLWGQEIGQFQLIQLKLATMEVARMNVRNMLFR
MSMEG_3783|M.smegmatis_MC2_155      GVIEECLRLSVDYAKSRKLWGQEIGQFQLIQLKLANMEVARMNVRNMLFR
TH_4655|M.thermoresistible__bu      GVIEECLRLCVDYAKNRKLWGQEIAQFQLIQLKLAKMEVARMNVRNMLFR
Mb2812c|M.bovis_AF2122/97           GIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMVFQ
Rv2789c|M.tuberculosis_H37Rv        GIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMVFQ
MMAR_1919|M.marinum_M               GIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMVFQ
MUL_2144|M.ulcerans_Agy99           GIINECHRLCVDYAKTRTLWGKNIGQFQLIQLKLAKMEVARINVENMVFQ
MAV_3680|M.avium_104                GIIDECHRLCVDYAKSRTLWGKNIGQFQLIQLKLAKMEIARMNVQNMVFH
Mvan_2342|M.vanbaalenii_PYR-1       GIINECHRLCLDYAKTRTLWGRNIGQFQLIQLKLARIEVARMNVQNMVFQ
MAB_2947c|M.abscessus_ATCC_199      GIINECHRRCLDYAKMRTLWGQNIGQFQLIQLKLAKMEVARINVQNMVFQ
MLBr_00737|M.leprae_Br4923          GIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYA
                                    *: : .   .: *:* *. :*..*. ** **: ** : :    .. ::: 

Mflv_3537|M.gilvum_PYR-GCK          VIESSQSGAPISLAEASAIKWYCSQAATDVAMDAIQLFGGNGYMTEYRVE
MSMEG_3783|M.smegmatis_MC2_155      VIESSQEGKPISLAEASAIKWYCSQAATDVAMDAVQLFGGNGYMTEYRVE
TH_4655|M.thermoresistible__bu      VIEAAEKGVPISLAEASAIKWYCSEAATDVAMDAVQLFGGNGYMTEYRVE
Mb2812c|M.bovis_AF2122/97           AIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYRVE
Rv2789c|M.tuberculosis_H37Rv        AIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYRVE
MMAR_1919|M.marinum_M               TLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYRVE
MUL_2144|M.ulcerans_Agy99           TLEKLKAGREPTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYRVE
MAV_3680|M.avium_104                TIERQQAGKPLTLAEASAIKLYSSEAATEVAMEAVQLFGGNGYMAEYRVE
Mvan_2342|M.vanbaalenii_PYR-1       TLERLGAGRMPSLAEASAIKLYSSEAATEAAMEAVQLFGGNGYMAEYRVE
MAB_2947c|M.abscessus_ATCC_199      TLEKLQHGKMPSLAEASAIKLYSSETATDVAMDAVQLFGGNGYMAEYRVE
MLBr_00737|M.leprae_Br4923          AAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVE
                                    .      *       ::* * :.*: * :.: :*:***** ** ::: **

Mflv_3537|M.gilvum_PYR-GCK          QLARDAKSLMIYAGSNEVQITHVARGLLSS-----
MSMEG_3783|M.smegmatis_MC2_155      QLARDAKSLMIYAGSNEVQITHVARGLLS------
TH_4655|M.thermoresistible__bu      QLARDAKSLMIYAGSNEVQITHVARGLLNA-----
Mb2812c|M.bovis_AF2122/97           QLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
Rv2789c|M.tuberculosis_H37Rv        QLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
MMAR_1919|M.marinum_M               QLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MUL_2144|M.ulcerans_Agy99           QLARDAKSLMIYAGSNEVQVTHIAKGLLG------
MAV_3680|M.avium_104                QLARDAKSLMIYAGSNEVQVTHIAKGLLSS-----
Mvan_2342|M.vanbaalenii_PYR-1       QLARDAKSLMIYAGSNEIQVTHIAKGLLSG-----
MAB_2947c|M.abscessus_ATCC_199      QLARDAKSLMIYAGSNEVQVTHIAKGLLAG-----
MLBr_00737|M.leprae_Br4923          RFMRDAKITQIYEGTNQIQRVVMSRALLR------
                                    :: ****   ** *:*::* . :::.**

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_2342	-	-	100% (418)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_3323	-	e-157	66.59% (416)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4205	-	3e-46	31.68% (404)	acyl-CoA dehydrogenase domain-containing protein